Cabrini Institute Annual Report 2015-16

C AB R INI IN STITUTE ANN UAL R EP ORT 2 01 5 -16 C ELEB R ATING 2 0 YE AR S OF ED UC ATION, R E S E ARC H AND HE ALTH PROMOTION

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CLINIC AL TRIAL S

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UNIVER SIT Y PARTNER SHIP S

PROJEC TS REVIEWED

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98

On average, Cabrini opened two new medical oncology trials per month

Cabrini has four major university partnerships across Australia

The Cabrini Human Research Ethics Committee reviewed 98 projects

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SIMUL ATIONS

NUR SE EDUC ATION

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Ten different simulation programs conducted in 2015-16

We have 12 manikins in use for training purposes

M ANIKINS

47k

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Our high-tech manikins cost up to $47,000 each

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ABOUT THE CABRINI INSTITUTE Established in 1996, the Cabrini Institute supports a wide range of education and research activities across Cabrini. Senior medical staff and researchers oversee a diverse research program, as well as developments in clinical education. The research program includes allied health, arthritis, back pain, cancer, care of the elderly, health literacy, medicine, nursing, palliative care, patient safety, psycho-oncology and surgery. The Cabrini Institute plays a significant role in the education of our current and future health professionals.

CONTENTS 8 Chair’s message 10 Executive Director’s message 14 Monash Department of Clinical Epidemiology at Cabrini Hospital 16 Cabrini Monash University Department of Medical Oncology – The Szalmuk Family Department of Medical Oncology 18 Cabrini Monash University Department of Medicine 20 Cabrini Centre for Nursing Research 22 Cabrini Monash University Department of Surgery – The Fröhlich West Chair of Surgery 26 Szalmuk Family Psycho-oncology Research Unit 28 Palliative Care Research Unit 30 Centre for Allied Health Research and Education 32 Intensive Care Unit 34 Clinical education 38 Stewardson Charitable Trusts Simulation Centre 40 Lee & Brian Johnstone Library 42 Grants and scholarships 44 Department staff 50 Ethics reporting 58 Publications 68 Cabrini Institute Council 76 Supporters

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C H A I R ’ S M E S S AG E

Renewal and celebration

By Professor Peter Fuller, Chair of the Cabrini Institute Council

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It is a pleasure to introduce the Cabrini Institute Annual Report 2015-16, which highlights both the scope and the achievements in education, research and health promotion across Cabrini.

At the beginning of 2016, Kellie-Ann Jolly retired after more than three years of service on the Cabrini Institute Council. Her input to a range of issues, particularly those related to health promotion, will be missed. We welcomed our newest member in July 2015: Professor Julian Smith. As Head of Monash University’s Department of Surgery, the Cabrini Institute Council will undoubtedly benefit from the experience and perspectives he brings.

It has been a pleasure to welcome our new Manager of Research Programs, Dr Emma Baker, who has supported the Cabrini Institute Council since joining us in 2015, as well as Sue Parkes, Director of the Cabrini Foundation, who joined us in 2015.

The Cabrini Institute Council noted with sadness the retirement of Dr Sue Burney as Head of the Szalmuk Family Psycho-oncology Unit. Sue had provided exemplary leadership in an area that strongly speaks to the mission of Cabrini. We have taken the opportunity, decided by Executive Director Professor Leanne Boyd and endorsed by the Cabrini Institute Council, to create a new academic department which merges psychooncology research led by Dr Jo Brooker and palliative care research led by Associate Professor Natasha Michael.

Mentorship for this new department is being provided

by Professor David Kissane, an internationally respected academic psychiatrist, psycho-oncology researcher and palliative care physician.

This year has been a year of change, evolution and indeed celebration, 2016 being the twentieth year of the Cabrini Institute. I remember being present at the formal opening of the Cabrini Institute on 26 July 1996 by the then Health Minister Dr Michael Wooldridge, with the blessing given by the late Archbishop Sir Frank Little KBE. We then retired to the Cabrini café to watch the final of the 1500-metre freestyle at the Atlanta Olympics play out, with swimmer Kieren Perkins winning the gold medal from lane eight. Perhaps this was an omen for the Cabrini Institute, which has certainly come out of ‘nowhere’ to achieve great success, albeit in a little more than 14:56.40 minutes.

To mark this twentieth year, a successful forum was held on 16 June, which showcased the Cabrini Institute’s achievements and challenges, past, present and future.

It was an opportunity to acknowledge those who had the vision to establish the Council 20 years ago, when this was most unusual for a private hospital. This vision has been realised not only with the current vibrant research and education programs but the recognition by the Cabrini Board of Directors and the Chief Executive Dr Michael Walsh that the Cabrini Institute is an integral and indeed essential component of the mission of Cabrini Australia.

On behalf of the Cabrini Institute Council, I would like to take this opportunity to acknowledge all those who made our twentieth anniversary such a successful event.

The Cabrini Institute Council continues to be impressed by the diversity, productivity and impact of the work of each of the Cabrini Institute’s departments. Associate Professor Helena Frawley leads the newest of these,

with the Centre for Allied Health Research and Education representing an exciting breadth of activity. Associate Professor Michele Levinson, Head of the Cabrini Monash University Department of Medicine and Clinical Dean, has delivered exciting innovations in medical education.

Professor Rachelle Buchbinder, Head of the Monash Department of Clinical Epidemiology at Cabrini Hospital, has continued to give Cabrini an international profile and we were delighted to recognise her appointment as a Fellow of the Australian Academy of Health and Medical Sciences. Associate Professor Gary Richardson through the Cabrini Monash Department of Medical Oncology, the Szlamuk Family Department of Medical Oncology, leads an active clinical trials program which provides our patients with access to the latest developments in cancer medicine and treatment. The Cabrini Monash University Department of Surgery, the Frölich West Chair of Surgery, led by Associate Professor Paul McMurrick has provided national leadership in the management, awareness and prevention of bowel cancer.

Finally on behalf of the Cabrini Institute Council, I wish to highlight and acknowledge the extraordinary leadership of Professor Leanne Boyd. She not only leads nursing research but is Executive Director of Nursing and the Cabrini Institute. It is both a privilege and pleasure for the Cabrini Institute Council to have the opportunity to interact with an outstanding group of committed researchers and educators. While it has been wonderful to reflect on the achievements of the Cabrini Institute over the past 20 years, it is truly exciting to be a part of the beginning of the next 20 years.

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E X EC U T I V E D I R EC TO R ’ S M E S S AG E

A milestone year

By Professor Leanne Boyd, Executive Director, Nursing and Cabrini Institute

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The role of education, innovation and research within healthcare is more important than ever before.

Healthcare faces immense challenges and opportunities.

Rising costs, an ageing patient population and workforce, declining revenue and a fragmented system are just a few of our challenges. These are complex, multidimensional problems that require innovative solutions.

In June 2016, we celebrated the twentieth anniversary of the Cabrini Institute. Over two decades, we have strengthened our commitment to clinical education and research. Our anniversary provided an opportunity to celebrate our achievements and acknowledge those who had the vision to establish an education and research organisation in a private health organisation. Associate Professor Doug Lording, inaugural Chair of the Cabrini Institute, was integral to its establishment and has had a key role in its development over two decades. After 20 years, Associate Professor Lording stepped down from his position on the Institute Council in July 2016. We expect he will continue to follow Cabrini’s, and the Cabrini Institute’s, future with interest.

The anniversary celebrations were marked with a research forum that showcased the achievements and challenges of the past, present and future. Presentations by internal and external invited speakers were engaging and demonstrated Cabrini’s breadth of education and research activities. Further, they provided insight for our future directions. A special twentieth anniversary project grant of $30,000 was awarded to Clara Officer (Nurse Manager) and Kelly Sherman (Clinical Nurse Specialist and Associate Nurse Manager) for their research project ‘Informing an autism-friendly Children’s Centre at Cabrini’.

A gala evening event at Melbourne’s Park Hyatt Hotel capped off the celebrations. It featured presentations and performances including guest speaker Simon McKeon AO, the recently appointed Chancellor of Monash University, who gave an address on the importance of

science, innovation and research. It was humbling to reflect on the history of the Cabrini Institute and how a strong commitment to research and the development of our future healthcare workforce, by a few key leaders, has resulted in the Cabrini Institute in which we take pride today. We look forward to the next 20 years of research and education achievements at Cabrini.

The past 12 months have produced significant outcomes across research, education and health promotion. Our research teams continue to conduct vital clinical and health services research that supports safe, high quality, evidence based care for our patients, residents and their families. We have developed excellent education curricula for our healthcare professionals that link workplace learning with formal university courses to better prepare our staff for the future.

Key relationships In the area of health promotion, we continued to work with the community through Let’s Beat Bowel Cancer to improve early detection of colorectal cancer. In 2015-16, Foundation 49: Men’s health moved to the Baker IDI Heart and Diabetes Institute. This is an exciting opportunity, which will enable this work to flourish in a high profile environment. In recognition of our longstanding relationship, Cabrini has signed a sponsorship agreement with Foundation 49: Men’s Health.

This year, the Cabrini Foundation with the support of the Cabrini Institute, funded more than $400,000 in grants and scholarships. This was more than double the previous year and attests to the great support for research provided by the Cabrini Foundation and our valued donors.

Our relationship with Monash Partners continues to grow. In 2015, Monash Partners Academic Health Science Centre (Monash Partners) was officially

recognised by the National Health and Medical Research Council as an Advanced Health Research and Translation Centre, acknowledging the collaboration’s capability to improve health outcomes through high impact translational research. Our research teams are collaborating with teams across the Monash Partners group and there have been excellent grant and publication outcomes as a result.

Our partnerships with Monash, La Trobe, Notre Dame and Australian Catholic universities continued to grow.

We celebrated the opening of the Australian Catholic University/Cabrini Clinical School in May 2016 and we look forward to developing enhanced teaching, learning and research opportunities for our students and staff via this collaboration.

Signature events We welcomed past patient Justin McLean, advocate and founder of www.thrivor.com, as guest speaker at the annual Peter Meese Memorial Lecture held in March 2016.

He discussed his personal experiences of being diagnosed with colorectal cancer and his subsequent and evolving view on the ‘the need to shift our thinking from survivors to thrivors’.

Cabrini Research Day was held in October 2015. The event was well received, attracting a large and diverse audience of staff, students and the community. For the first time, the program included concurrent oral sessions enabling more opportunities for novice and early career investigators to present their work. Two excellent keynote presentations were delivered by Associate Professor Andrew Way (CEO of Alfred Health) and Professor Christina Mitchell (Academic Vice-President and Dean, Faculty of Medicine, Nursing and Health Sciences, Monash University) focusing on our theme for the day: translational research.

New directions In November 2015, the Cabrini Board of Directors approved the overarching strategic direction for Cabrini for 2016-2020. Subsequently, it approved the Cabrini Institute’s strategic plan in May 2016. In this strategy, innovation is embedded within education, research and health promotion. Further, the Cabrini Institute will oversee an exciting new initiative, the Cabrini Centre for Innovation, due to open in 2017. Our goal is: “To courageously support and facilitate the broader Cabrini strategy through the delivery of education, research and innovation, aligned to the organisation’s heritage, mission and values.”

I would like to thank our excellent researchers, clinicians, administration team and educators who have worked with such passion and commitment these past 12 months. We are most grateful to the members of the Cabrini Institute Council for their ongoing guidance and to our Cabrini doctors, nurses and allied health staff for their support of our undergraduate and postgraduate students. Also, we acknowledge each and every patient, resident and family member who has contributed to our work by participating in a clinical trial or supporting education for our health professionals. We especially thank our generous donors for their continued support of research and education activities within the Cabrini Institute. Finally, I thank all who have contributed to this year’s report. We look forward to the challenges and opportunities to come over the next 12 months.

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C AB R INI IN STITUTE DEPARTM ENT S

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M O N A S H D E PA R TM E N T O F C LI N I C A L E P I D E M I O LO G Y AT C A B R I N I H O S P I TA L

The focus of our department is to perform high-quality clinical research with an emphasis on answering clinically important questions that can be translated into better quality patient care and outcomes.

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From left: Professor Rachelle Buchbinder (Head of Department), Dr Renae Johnston, Dr Margaret Staples (top), Joan McPhee (bottom) and Dr Allison Macpherson.

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Our department houses one of two international Cochrane Musculoskeletal Group editorial bases tasked with editorial oversight of all Cochrane reviews in this area. We also manage the Australian Rheumatology Association Database, a national longitudinal registry collecting long-term outcome data about people with inflammatory arthritis with a focus on biological therapies.

Our department is a founding member of the Australia and New Zealand Musculoskeletal Clinical Trials Network formed to facilitate the conduct of large-scale clinical trials to answer the most critical questions for common musculoskeletal conditions. In April 2016, we organised our second international summit and now have an agreed structure and governance, as well as a plan for endorsing trials. We are currently forming the Scientific and Consumer Advisory Groups and have shortlisted applicants for our first Executive Officer position.

Our current projects include: • An NHMRC funded, randomised, controlled trial comparing autologous platelet-rich plasma injection to glucocorticoid injection and placebo for tennis elbow • Understanding the health literacy of patients attending Cabrini – the results of this project were presented in a series of patient, clinician and management workshops at the end of August 2016 and will be used to identify strategies that Cabrini may consider for improving the patient experience • Development of a consumer decision tool that provides evidence-based information and the benefits and risks of arthroscopic treatment for knee osteoarthritis • Development of a core set of outcome measures for use in trials of shoulder pain

• The consensus of exercise reporting template: a tool to improve the reporting of exercise interventions in clinical trials Important aims of our department include identifying effective treatments and addressing evidence-practice gaps. For example, our project determining the health literacy profile of patients who have been admitted to hospital at Cabrini Malvern has identified a range of health literacy needs across our patient population.

Consideration of strategies to address them may improve the patient experience. Similarly, we have identified that consumer information about knee arthroscopy that is easily accessible on the Internet does not provide optimal evidence-based information about the potential benefits and risks of arthroscopic treatment for people with knee osteoarthritis. While there is consistent evidence from high quality trials that arthroscopic treatment is ineffective in treating this condition and may be harmful, and guidelines consistently advise against its use, there continues to be overuse of this treatment in Australia.

Development of a decision tool that includes evidencebased information about this procedure may be one valuable approach to reduce its use. We are currently performing focus group discussions with patients and clinicians to inform the tool, which will then be tested in a variety of settings before planning for a high quality trial to evaluate its efficacy.

Research highlights We were part of a team that was awarded a five-year $9.5m NHMRC program grant entitled ‘Using healthcare wisely: reducing inappropriate use of tests and treatments’ that will commence in 2017. Investigators include Professor Rachelle Buchbinder (Cabrini) and Professors Paul Glasziou (Bond University), Chris Maher

(University of Sydney) and Kirsten McCaffery (University of Sydney). Our proposed program will focus on unnecessary tests and treatments that harm patients and divert scarce resources from where they are most needed. We will focus on understanding the problem and identifying and evaluating possible solutions linked with processes for translation and implementation.

Another highlight was the completion and publication of the consensus on exercise reporting template. This work was led by postdoctoral fellow Dr Susan Slade supported by an international panel of exercise experts.

This template aims to improve the description of exercise interventions in clinical trials so that effective programs can be replicated and taken up in practice.

Future plans Professor Buchbinder, together with Dr Joel Gagnier (USA), Arianne Verhagen (Netherlands), and OMERACT Fellows Matthew Page (Australia but currently UK) and Hsiaomin Huang (USA), led the core outcome measurement set for clinical trials in shoulder disorders special interest group at the Outcome Measures in Rheumatology (OMERACT) conference in May 2016, held in Whistler, BC, Canada, with funding from the Patient-Centered Outcomes Research Institute. Based upon systematic reviews of clinical trials investigating treatments for shoulder pain and a Delphi study that elicited expert and patient views, we have identified a core domain set. The next step is to identify potentially suitable tools to measure each domain and perform a systematic review of their psychometric properties. We are currently planning the initial projects for our program grant that will have a focus on understanding the factors that contribute to overuse of tests and treatments in the musculoskeletal field.

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C A B R I N I M O N A S H D E PA R TM E N T O F M E D I C A L O N CO LO G Y T H E S Z A L M U K FA M I LY D E PA R TM E N T O F M E D I C A L O N CO LO G Y

Our department specialises in clinical research using new therapeutic agents in the treatment of many different cancers and haematological malignancies.

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From left: Associate Professor Gary Richardson (Head of Department), Nina Box (top), Dr Ben Brady (bottom), Mary Lane and Associate Professor Ian Haines.

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Currently most of our studies involve either immunotherapeutic drugs or targeted therapies.

Immunotherapies are treatments that restore or enhance the immune system’s ability to fight cancer. Studies have been completed in melanoma, and we are embarking on trials in lung cancer, ovarian cancer and a wide range of other malignancies. Targeted therapies are medicines or other substances that block the growth and spread of cancer by interfering with specific molecules (that is, molecular targets) that are involved in the growth, progression and spread of cancer. These therapies are a cornerstone of precision medicine, a form of medicine that uses information about a person’s genes and proteins to prevent, diagnose and treat disease.

As well as helping to find better treatments, therapies and diagnostic tests, clinical trials can provide direct benefits for our patients that include: • The opportunity to be given a new intervention that may be better for their condition or that has fewer side effects than standard treatment.

• Access to the newest interventions before they are made available to the general public.

• The chance for our patients to play an active role in their own healthcare and gain a greater understanding of their disease or condition.

• Advice, care and support from trained clinical staff who understand their disease or condition.

• Closer monitoring of their condition, care and treatment.

Clinical trials may be valuable for people with rare or difficult-to-treat conditions for which there may be limited evidence about how the condition is best treated or managed.

Research highlights During the past 12 months, we have opened two new clinical trials on average each month, largely using immunotherapeutic and targeted treatments. In January 2016, we were the first centre in the world to open the JAVELIN trial, a randomised study comparing standard chemotherapy with Avelumab, a new anti-PD-L1 agent, which stimulates the body’s immune system to fight ovarian cancer. Since then, we have opened two further studies using anti-PD-L1 agents to treat ovarian cancer (and a range of other cancers).

In June 2016, Associate Professor Gary Richardson was awarded the John Sutherland Hamling Research Grant to initiate a dietary intervention study in women who have breast cancer and are receiving chemotherapy.

Future plans We anticipate a significant increase in trial activity in the next 12 months, largely because of access to many new immunological and targeted therapies. As well as expansion in our clinical activities, we will embark on new areas of research, particularly in partnership with other departments and organisations. We have a large research grant to carry out a study in dietary intervention in women receiving chemotherapy for breast cancer.

There are other opportunities to work with the Centre for Allied Health Research and Education, particularly in the area of exercise intervention in cancer patients. We have exciting projects in partnership with the Cabrini Monash University Department of Surgery, which has an extensive patient database and is now creating tissue microarrays to correlate tumour mutation patterns to patient outcomes.

There is an organoid project, which will be invaluable in helping determine the most effective chemotherapeutic agents for individual projects. Finally, we will partner with the Monash Partners Comprehensive Cancer Consortium in developing new translational research projects.

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C A B R I N I M O N A S H U N I V E R S I T Y D E PA R TM E N T O F M E D I C I N E

Our department provides a focus for research and education in medicine within Cabrini. We emphasise research that can be translated into improvements in medical practice and models of care for our patients.

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From left: Associate Professor Michele Levinson, Gaya Sritharan, Georgina Johnstone (top), Anthea Gellie (bottom), Associate Professor Michele Levinson (second from left) with doctors Justin Cole, Chris Yeo, Michael Rose and Kelvin Kuik.

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We are primarily interested in research as it relates to the care of older patients, particularly on end-of-life care, incorporating issues such as communication, quality of death, the role of cardio-pulmonary resuscitation (CPR) and other treatments at the end-of-life stage, understanding of language and shared decision-making.

We are a multidisciplinary team with backgrounds in medicine, science, psychology, publishing and editing and the arts.

The focus of our work is to ultimately improve patient care at the end of life, by understanding what patients value and how our healthcare system can best meet those needs. This involves an understanding of end-of-life care from the perspectives of patients, doctors, nursing staff, other healthcare professionals and hospital systems.

Research highlights In 2015-16, we published a long-term prospective study that examined the health outcomes of 348 patients aged 80 years and older following an admission to the intensive care unit (ICU). Quality of life and functional status were examined up to two years after discharge from the ICU. Patients were asked whether on reflection they considered the ICU admission to have been of benefit to them; we assessed based on their quality of life and ability to perform activities of daily living such as showering and dressing. The results showed that quality of life and previous lifestyle were maintained, and that most patients valued the admission. The importance of this work is to highlight that consideration of treatment options for older patients should include factors other than age.

In a second publication, we explored the issue of decisionmaking in healthcare for older patients by asking patients aged 75 years and older what they knew and understood about CPR. Most patients indicated a poor understanding of what happens during CPR, and an over-estimation of the likelihood of successful resuscitation in a person of

their age group. These findings are important, as they highlight that shared decision-making in medicine relies on accurate knowledge and understanding. Discussion about CPR is important in consideration of goals of care and end-of-life care planning.

Future plans In the 2016-17 Cabrini Foundation research grant funding round, we secured funding to support a research project on improving recognition and screening of delirium in rehabilitation and acute care settings. This study will examine the effectiveness of a delirium intervention on nurse recognition, screening and documentation of delirium; outcomes and hospital remuneration. Nursing staff at Cabrini Malvern and Cabrini Rehabilitation will participate in an education program designed to increase knowledge of delirium, recognition and management.

Also, nurses will be trained in the use of a combined delirium screening tool to be integrated into patient notes. To support this work, a ward-based delirium awareness campaign will be held, in order to provide information to patients, carers and staff. Information about the scale of the financial burden of undiagnosed delirium will be calculated. The research will inform current practice and process improvement around recognition and screening for delirium symptoms by nursing staff and contribute to existing literature by providing Australian data on the prevalence and cost of delirium in the acute care and rehabilitation settings.

We are participating in a national multi-site audit of the care received by dying patients in acute hospitals, coordinated by the Australian Commission on Safety and Quality in Health Care. This review will evaluate care provided in the 2015 calendar year, and it extends our work examining the role of the medical emergency team in the provision of end-of-life care.

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C A B R I N I C E N T R E FO R N U R S I N G R E S E A RC H

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At Cabrini, we believe that patients, residents and their families have the right to expect that their care will be based on the best available research evidence.

As nurses play a pivotal role in provision of care, research related to nursing practice and key issues is essential to ensure continuous improvement and safe, effective and evidence-based healthcare.

From left: Professor Lee Boyd, Elizabeth LeHunt (top), Patrick Mader (bottom), Will Dunlop and Louise Alexander.

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Improving the patient, family and community experience of healthcare is integral to the research agenda of the Centre for Nursing Research. Nurses’ frontline roles put them in a unique position to understand the needs and concerns of patients, residents and their families. Encouraging nurses to lead and contribute to research keeps research activity focused on patient care and the needs of our healthcare service. Further, this supports meaningful engagement with patients, residents, carers and families. Nursing research can help to make healthcare more efficient and cost-effective.

By encouraging ongoing improvements to practice and investigating new models of care, nursing research can inform new practices that improve the patient experience, prevent waste and improve efficiency.

The acquisition of research knowledge equips nurses with the knowledge and analytical skills they need to make informed decisions and contribute effectively to new developments, from individual improvements in practice to the redesign of services. This culture of enquiry ensures that we constantly strive to improve.

Nursing research and evidence implementation are essential parts of the education and training of existing and future nursing workforce.

Research highlights In 2015-16, three major highlights in the Centre for Nursing Research were as follows: • The online resource for religious and cultural advance care planning nursing research project was awarded funding from the Commonwealth Government Department of Health from March 2015. In carrying out this project, we are working in partnership with government, religious and cultural organisations.

The aim is to develop a comprehensive, national religious and cultural advance care planning website (ACPTalk) for end-of-life decision making in various denominations. This is intended to complement

existing advance care planning by providing guidance to health professionals in engaging people of diverse religions and cultures in advance care planning.

The website will be available to the public.

• The purposeful rounding project has been trialed at four Cabrini campuses with the aims of reducing falls and pressure injuries, as well as increasing patient and staff satisfaction. It has been fully implemented across all wards at Cabrini Brighton based on positive results at this hospital. A final data evaluation is being conducted.

• We are conducting a peripheral intra-venous cannula point prevalence study to quantify and qualify the utilisation of peripheral intravenous cannulas (PIVC) at Cabrini Malvern and Cabrini Brighton in collaboration with St John of God in Subiaco. As a result of the study, we expect to gain a clearer understanding of the utilisation and purpose of PIVC at the participating hospitals, in order to: reduce risk of falls secondary to PIVC; enhance the patient experience; reduce infection risk due to unnecessary cannulation; and reduce costs associated with unnecessary PIVC. As a caring discipline within a Catholic organisation, Cabrini’s Centre for Nursing Research is in a position to explore religious and cultural considerations associated with advance care planning. It is hoped that the new ACPTalk website will create benefits by increasing uptake of advance care planning conversations, supporting health professionals through the process with people of different religions and cultures and increasing community awareness of this important issue.

This is intended to contribute to improving end-of-life care to the wider community.

Quality and patient safety projects within the Centre for Nursing Research are focused on innovative approaches to improving clinical practice and service delivery. As projects are centred on falls and pressure

area prevention, benefits to patients and families would include reduction of these events, greater safety for patients and a reduction in hospital bed days necessitated by harm of falls.

Further, the Centre for Nursing Research has contributed to community care in the following countries: • Ethiopia, Africa – where we conducted a needs analysis at St Mary’s Hospital in Dubbo • Madang, Papua New Guinea – where we assisted the Divine Word University with its Bachelor of Medicine and Bachelor of Surgery curriculum Future plans Partnering effectively is an important element of the Cabrini Institute’s strategic plan 2016-2020. Currently we are exploring opportunities with our university partners to develop an Associate Professor level chair position to oversee the Centre for Nursing Research in 2017. We consider this to be an opportunity to build on excellent work in nursing research at Cabrini and to situate the centre to succeed in the future. We remain invested in supporting our nursing and midwifery workforce by better understanding our past, current and future needs. In 2016-17, Cabrini’s first nursing and midwifery strategic workforce plan will be implemented. The Centre for Nursing Research will continue to evaluate its utility, accuracy and feasibility, as well as monitoring implementation of the plan. An exciting direction is that innovation is being included within our research themes.

We plan to trial new processes, methods, ideas and products that will facilitate a better experience for our patients, residents and their families, as well as increasing the availability of care in our community.

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C A B R I N I M O N A S H U N I V E R S I T Y D E PA R TM E N T O F S U RG E RY T H E FRÖ H LI C H W E S T C H A I R O F S U RG E RY

Established in 1998, the Chair of Surgery at Cabrini is a joint venture between the Cabrini Institute and Monash University. It was the first of its kind in the Victorian private medical sector and one of the first in Australia. The chair was endowed as the Fröhlich West Chair of Surgery in 2004.

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From left: Associate Professor Paul McMurrick, recording the ‘Everyday Health’ program, Emeritus Professor Adrian Polglase (top), Dr Simon Wilkins (bottom) and Mr Stephen Bell (right).

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During 2015-16, the Cabrini Monash University Department of Surgery continued its strong clinical research focus and quality assurance leadership at Cabrini and in the broader Australian medical community.

Through our collaboration with Let’s Beat Bowel Cancer (LBBC), the Cabrini Monash University Department of Surgery continued a number of significant initiatives designed to improve the health of the Australian community, particularly in relation to bowel cancer.

Thanks to the efforts of dedicated committee members that include Geoff Stansen (Chair), Des Jackson, Richard Morgan AM (past chair), Andrew Facey and Sue Parkes (Cabrini Foundation), LBBC has been successful with numerous public engagement initiatives during 2015-16.

AL Polglase Visiting Professor Program In 2015, we hosted Professor Frank Frizelle, head of the department of surgery at the University of Otago, New Zealand. Named in recognition of Emeritus Professor Adrian Polglase for establishing and formalising colorectal surgery and education at Cabrini, Professor Frizelle became involved with a vast range of educational activities during his visit to Australia. These commitments included meeting with trainee surgeons for professional extension, involvement with an instructive operating theatre session, a dinner lecture discussing advanced surgical techniques delivered to the Victorian members of the Colorectal Surgical Society of Australia and New Zealand (CSSANZ) and a public lecture entitled ‘Colorectal surgery – can we do better?’ held at Cabrini.

Beaumaris Football Club LBBC readily welcomes any potential third party event organisers in advancing this important cause. The Beaumaris Football Club staged a successful fundraising event which supported our work in raising bowel cancer awareness and conducting world-leading research initiatives. Associate Professor Paul McMurrick spoke at

this event, explaining the benefits of increasing the public uptake of bowel cancer screening through educating the general public.

Everyday health Associate Professor Paul McMurrick extended the bowel cancer prevention and screening messages to a broad public audience through appearing on Network Ten’s new television program entitled Everyday Health. The program covers a diverse range of topical health subjects such as health and fitness, food and nutrition, family, and relationships, in order to promote greater health awareness. In his segment, Associate Professor McMurrick discussed bowel cancer testing options, curative approaches, and explained the details and implications of the national bowel cancer screening program in a way that was suitable for a general audience.

In 2015-16, leadership of the Monash Partners Cancer Consortium Colorectal Tumour Stream research group was maintained and strengthened, and has led to the successful awarding of several world-leading research grant applications.

Colorectal Fellow Initiative The colorectal fellowship program continued in 2015-16 with the appointment of Dr Angus Lee. Dr Lee has initiated several research projects, including the impact of lymph node collection at the time of surgery and the predictive nature of the blood marker carcinoembryonic antigen (known as CEA) in determining the outcomes of colorectal cancer. Further, Dr Lee has assisted in both colorectal and general surgery while at Cabrini. He has provided extensive support in the teaching and supervision of medical students, as well as his clinical duties on the ward and in theatre.

Professional representation Members of the department continued their important work as clinical representatives of professional bodies including: • Joint Council of Monash Partners Comprehensive Cancer Consortium: Associate Professor Paul McMurrick • Executive Council, Victorian Clinical Oncology Group: Associate Professor Paul McMurrick • Member of the Training Board in Colon and Rectal Surgery: Mr Stephen Bell

Leadership in clinical research In 2015-16, the bi-national colorectal cancer audit of the CSSANZ derived from the Cabrini colorectal neoplasia database continued. It now includes data from more than 13,600 colorectal cancer treatment episodes across Australia and New Zealand, with collaboration from more than 83 centres. Another annual report was published from the updated database. Cabrini continues to lead the extended dataset and now has highly detailed data entry on 2600 cancer treatment episodes.

• Cabrini Director of Surgical Training: Mr Martin Chin

Research highlights

• Members of the Victorian Advisory Panel for the National Bowel Cancer Screening Program: Mr Stephen Bell and Associate Professor Paul McMurrick

Major research highlights included the awarding of several prestigious grants:

• Member of Executive Council, CSSANZ and International Society of Digestive Surgery: Associate Professor Paul McMurrick

• Victorian Cancer Agency $2m Translational Research Project Grant (2016-2018) – awarded for the project ‘Super-enhance template RNAs as predictive biomarkers of BET inhibitor sensitivity in prostate and colorectal cancer’. Applicants included Dr Arun Azad

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C A B R I N I M O N A S H U N I V E R S I T Y D E PA R TM E N T O F S U R G E RY – T H E F R Ö H L I C H W E S T C H A I R O F S U R G E RY

(lead), Dr Ron Firestein, Associate Professor Helen Abud, Associate Professor Paul McMurrick, Professor Gail Risbridger and Dr Simon Wilkins.

• CSSANZ $100,000 grant (2016-17) and Cabrini Foundation grant $50,000 (2015) – awarded for the project ‘ADIPOSe – Australasian decrease in intrapelvic obesity for surgery trial – using VLEDs to reduce weight and improve outcomes in obese individuals undertaking rectal cancer surgery’. Applicants were Mr Steven Bell, Associate Professor Paul McMurrick and Dr Simon Wilkins.

• NHMRC Project Grant $646,698 (2016-18) – awarded for the project ‘The role of snail proteins in mediating intestinal stem cell identity’. Applicants were Professor Helen Abud, Associate Professor Gary Hime, Professor Leanne Jones and Associate Professor Paul McMurrick.

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• Monash University strategic grant $49,810 (2015) – awarded for the project ‘The role of snail proteins in mediating intestinal stem identity’. Applicants were Professor Helen Abud, Associate Professor Dena Lyras, Professor Roger Daly, Associate Professor Paul McMurrick, Associate Professor Marcel Nold and Dr Claudia Nold.

Future plans The department’s research program continues to focus on three key streams: screening and prevention of bowel cancer, improving patient treatment and patient outcomes following treatment for bowel cancer. In 2016, we will begin a new collaborative research project based on cutting edge research techniques.

Organoid culture, a cutting edge technique in researching human diseases, is a method for growing live cells from tumours and normal tissue that more accurately simulates how the tissue is structured in the body than previous methods. Culturing organoids means we can now study the biology and genetics of bowel cancers growing outside of a patient’s body. Shortly after a diagnosis of bowel cancer, tumour and normal tissue specimens can be taken from the patient, grown in a laboratory and then subjected to a number of treatment protocols including chemotherapy and radiation therapy to ascertain which treatment protocols will work best for that patient’s tumour. This ground breaking research has the potential to create personalised medicine, attuning cancer treatment to individual requirements. We are at the forefront of this process. Currently we are looking to create with Monash University and our collaborative research partners a revolutionary personalised medicine program based at Cabrini with great potential benefits to colorectal cancer patients.

In public education, LBBC has commenced developing a new national program designed to provide the community with personalised information in relation to bowel cancer in collaboration with Production Company Burning House. After answering a series of questions via an online portal pertaining to general health, bowel cancer risk factors, family history and potential symptoms, individuals will receive a print-out summary of their screening recommendation which can then be used as a starting point for discussion with their GP.

Forefront of life-changing research After more than 19 years of laboratory research involvement, Dr Simon Wilkins quite simply loves his job.

As Research Fellow for the Cabrini Monash University Department of Surgery, Dr Wilkins is at the forefront of potentially life-changing research.

Currently the department has more than 30 projects on the go, and all are about improving the outcomes for patients.

Dr Wilkins, who joined the department in October 2013, says some of the more exciting projects he is working on include developing a tissue micro array and working with the colorectal database, which records information on more than 2500 patients who have undergone colorectal surgery. Patients are from Cabrini and a number of hospitals across Melbourne. “It gives us a fantastic research resource to use for our own research,” Dr Wilkins said. He says the research had allowed them to look at specific outcomes, for example colorectal cancer in people older than 90 years of age, and in patients who have diabetes.

Dr Wilkins says the team is working on an organoid project, which involves growing live cells from tumours and normal tissue, which can then be tested further against various treatments. “At the time of surgery,

we take a small chunk of the tumour and put it into a special growth medium where it’s taken to the lab so we can test anti-cancer drugs on them and see which patients are susceptible to which drugs,” he said. Dr Wilkins says the samples will be subjected to a number of treatment protocols including chemotherapy and radiation therapy to determine which treatments would work best for that patient’s tumour.

“This could be a significant step towards personalised treatment.”

Within his role, Dr Wilkins is responsible for coordinating these projects, sorting the ethics for all projects, analysing the data, writing reports and submitting the information to scientific journals. He can be watching a surgical robot in surgery one day to assisting with samples the next, no day is the same. “There’s always something new, it’s certainly one of the best jobs I’ve had.”

He said working with “a really good team of people who are all striving for a common goal” is one highlight of his role. “We are all heading in the right direction and we’re really making progress and pushing these projects through. And the potential to change the way colorectal cancer is treated – it’s a fantastic combination.”

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S Z A L M U K FA M I LY P S YC H O - O N CO LO G Y R E S E A RC H U N I T

The Szalmuk Family Psycho-oncology Research Unit was established in 2008. We strive to achieve real clinical research outcomes that can make a difference to people’s lives.

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From left: Dr Sue Burney (Head of Unit until January 2016), John Julian, Professor David Kissane (top), Jane Fletcher (bottom) and Dr Jo Brooker (Research Fellow).

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We work to conduct best practice, evidence-based research, clinical interventions and education with respect, integrity and understanding. Our research interests range from cancer screening in the general population, treatment decision-making, psychological and social factors that influence adjustment to cancer, unmet needs of cancer patients and their families, psychological interventions for people affected by cancer, and psychological and social factors in palliative care settings. After founding the unit in 2008, Dr Sue Burney retired in January 2016. However, she remains actively involved in supervising research students and supporting Dr Jo Brooker in the work of the unit.

In 2015-16, we hosted the clinical placements of four postgraduate psychology students from Deakin, La Trobe, Monash and Australian Catholic universities.

All postgraduate psychology students on placement were registered as provisional psychologists and undertook placements of two days per week. The students contributed to Cabrini by providing counselling to patients and family members; developing and facilitating our psycho-education and mindfulness sessions; and supporting research activities. Professor David Kissane provided students with training in meaning and purpose therapy and the students assumed the role of therapists in a trial for patients who have advanced cancer. With the retirement of Dr Burney, the clinical placement program ceased in January 2016.

Throughout 2015-16, the psycho-oncology team continued to strengthen relationships with members of the Palliative Care Research Unit, as demonstrated by collaborative work on the meaning and purpose therapy trial and a demoralisation scale project. In May 2016, we were delighted that Tanya Osicka, a registered psychologist and former psycho-oncology placement student, joined the unit to continue work on the meaning and purpose therapy trial.

Research highlights With the support of a $30,000 grant from the inaugural Cabrini Foundation Research Grant Round, we undertook a pilot study of the group-based, eight-week mindful self-compassion program for people diagnosed with cancer. Thirty Cabrini patients participated in the program, which was delivered by leading Australian mindfulness trainer John Julian. Participants reported a high level of satisfaction with the program, with most indicating they were highly likely to recommend it to other cancer patients. Participation in the program was associated with reductions in anxiety, depression, fear of cancer recurrence, and loneliness, and an increase in mindfulness.

Internationally, this appears to be the first study of the mindful self-compassion program in cancer patients. Our results provide preliminary evidence that the program is safe, feasible and acceptable to this patient group.

We completed a study to refine the 24-item demoralisation scale originally developed by Professor Kissane and colleagues. Over the past three years, this multi-site study was undertaken by Monash University psychology doctoral student Sophie Robinson, under supervision by Professor Kissane, Dr Brooker and Dr Burney. Recruitment was supported

by Courtney Hempton and Associate Professor Michael.

Demoralisation involves lowered morale, difficulties with coping, and feelings of hopelessness, helplessness, meaninglessness and purposelessness. Responses from 211 palliative care patients were utilised to develop a simpler and briefer scale, the 16-item demoralisation scale II − making it more practical for clinicians and researchers to assess demoralisation in clinical settings.

Our review of the scientific literature revealed that demoralisation is present in 13 to 18 per cent of patients in palliative care settings. Two papers on the development of the demoralisation scale II have been published in the prestigious Cancer journal and the work was presented at the Annual Conference of the European Association of Psychosomatic Medicine. Furthermore, we have

published two review papers on demoralisation in international journals.

Over the past year, Cabrini patients have benefited from participation in the psychological programs offered through the mindful self-compassion pilot study and the meaning and purpose therapy trial, as well as by attending the six-session psycho-education program. Our research on healthcare provision and the unmet needs of patients has yielded important information to assist service providers in improving models of care.

Future plans A key aim is to build on the exciting results from the mindful self-compassion pilot study. Dr Brooker and collaborators will seek funding for a larger trial of the program for cancer patients. We will also explore opportunities to investigate whether the program is of benefit to family care-givers of cancer patients and staff employed in oncology and palliative care services.

In 2016-17, we will build on our earlier work that identified the need to better support parents diagnosed with cancer in communicating about cancer with their children.

Together with colleagues from Monash University, we will undertake a review of the evidence for interventions designed to help families with non-adult children in communicating about cancer throughout their disease, from diagnosis through to palliative care. The purpose of the review is to identify an intervention suitable for implementation at Cabrini.

Professor Kissane and Dr Brooker, in collaboration with a national group of researchers including Cabrini Institute biostatistician Dr Margaret Staples, are seeking funding to undertake a study to establish the prevalence of psychiatric disorders among Australians who have cancer. The findings would inform improved service planning and delivery to such patients, with collaborative and innovative models of care designed to substantially improve outcomes for patients while reducing healthcare costs.

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C A B R I N I PA LLI AT I V E C A R E R E S E A RC H U N I T

Established in April 2014 through generous donations to the Cabrini Foundation, the Cabrini Palliative Care Research Unit collaborates with researchers and clinicians within Cabrini and across partnering organisations to inform holistic care of Cabrini patients with a life-limiting illness and their families.

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From left: Associate Professor Natasha Michael, Associate Professor Clare O’Callaghan, Cabrini Palliative Care, Prahran and Dr Merlina Sulistio.

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In 2015-2016, our research team has focused on the following areas: • Clinical translation research emphasising symptom management • End-of-life and future care planning • Spiritual and religious needs in advanced illness • Quality improvement impacting holistic palliative care • Models of service provision based on best practice to improve palliative care access • Meaning and purpose therapy in advanced cancer • Refinement and revalidation of the demoralisation scale A highlight of many of these research endeavours have been partnerships with Dr Jo Brooker from Cabrini’s Szalmuk Family Psycho-Oncology Research Unit and Professor David Kissane, Professor of Psychiatry, Monash University.

Cabrini Palliative Care is an accredited training site of the Royal Australian College of Physicians. In 2015-16, five advance trainees in palliative medicine and geriatric medicine were supervised on case studies and projects covering areas of quality assurance and systematic reviews on a variety of topics. Our team published five refereed journal articles, four book chapters, four conference proceeding papers, and presented/co-authored papers at eight national and international conferences.

External collaborations included: Health Issues Centre, University of Sydney, Peter MacCallum Cancer Centre, Monash Health, Deakin University, Swinburne University, University of Melbourne, Caroline Chisholm Centre for Bioethics and the Victorian Cancer Council.

In 2015-16, Associate Professor Natasha Michael was appointed Head of Palliative Medicine, University of Notre Dame, Sydney School of Medicine.

Research highlights Our research investigating a change to Cabrini’s model of palliative care – from a service entirely focused on endof-life care to one addressing symptoms and the support care needs of people experiencing life-limiting conditions – was selected as an editor’s choice article in the journal Palliative Medicine. This work inspired an outcome evaluation of patients with advanced cardiorespiratory illnesses under Cabrini’s shared care model, led by Dr Merlina Sulistio. We continue collaborate with the psycho-oncology team to support ongoing research in meaning and purpose therapy led by Professor David Kissane.

A particular strength of the palliative care research team is our skill in qualitative research, evaluation of service delivery and intervention based studies, which enables research findings to uncover what is meaningful and makes the most difference to patients, their families and staff. This was evident in the model of palliative care research which found that the transition placed additional stressors on staff managing broader patient and family needs. Additional training and support needs were identified and addressed, ensuring that Cabrini patients receive world-class, evidence based care.

The research team was honoured by numerous invited speaker invitations, including those in Munich (Germany), Boston (USA) and Beijing (China), as well as local opportunities. At the Fifth Annual Conference on Advance Care Planning and End-of-Life Care in Munich, Associate Professor Michael presented her series of studies promoting a patient- and family-centred approach to advance care planning in people affected by cancer.

This work included the first international research on the vignette (written short story) technique’s utility in promoting advance care planning. Associate Professor Clare O’Callaghan presented the 2015 Annual Lecture in Psycho-oncology at St Vincent’s Hospital, Melbourne, which focused on 25 years of her research examining

music and music therapy interventions designed to improve the lives of cancer patients, families and oncology staff. As a qualitative healthcare researcher, Associate Professor O’Callaghan was invited to design qualitative research approaches and conduct analyses in multiple psycho-oncology, nursing, spirituality and palliative care projects at Cabrini and Peter MacCallum Cancer Centre, and in service quality evaluation at the Cancer Council Victoria.

Our ongoing involvement with the Victorian palliative care and geriatric training program ensures that our patients and their families obtain the best care from the most skilled doctors and ongoing capacity building for the dissemination of palliative care skills across the community.

Future plans In 2016-17, the palliative care research team looks forward to ongoing and new multidisciplinary research collaborations. We aim to secure additional external competitive grants, build on our program of education and training, and align our activities with Cabrini’s strategic vision and the recently published strategic aims of the Victorian Palliative Care Framework.

After securing a Cabrini Foundation Research Grant, Associate Professor O’Callaghan will focus on researching spiritual encounters and requirements of Cabrini patients who have incurable, serious illnesses. This collaboration includes Cabrini pastoral care, psycho-oncology, statistical staff, Cabrini accredited medical practitioners and Catholic Health Australia. We continue to seek external funding to further explore our use of the vignette technique in end-of-life research and to support the ongoing development of research skills in our junior staff.

We aim to develop areas of research in collaboration with our colleagues in geriatric medicine and chronic disease to enhance care provided to this group of patients at Cabrini.

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C A B R I N I C E N T R E FO R A LLI E D H E A LT H R E S E A RC H A N D E D U C AT I O N

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Cabrini’s Centre for Allied Health Research and Education focuses on translational research, implementing evidence-based clinical guidelines, and primary research investigating important gaps in knowledge of allied health clinical care. Our goal is to improve the health of Cabrini patients and our local community through development and implementation of clinically-focused research which translates into best clinical practice.

From left: Associate Professor Helena Frawley, Jason Wallis, Dr Tash Brusco (top and bottom) and Hema Navaratnam.

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Cabrini’s Centre for Allied Health Research and Education has been established just three years. Its activities are led by Associate Professor Helena Frawley, under a joint appointment with La Trobe University. Allied health research encompasses research activity from the 11 allied health disciplines represented at Cabrini, across acute, rehabilitation and community care settings. Some research projects underway include:

Research-active staff generated consistent research output last year demonstrated by:

• A multidisciplinary rehabilitation program for patients following surgery for abdomino-pelvic cancer

• 25 national and international conference presentations

• Implementation of clinical guidelines for stroke management

• 14 publications • four staff receiving internal, competitive funding for research projects • one team have been part of an externally competitive grant award • increase in research higher degree enrolments in the physiotherapy and speech pathology disciplines The centre’s leadership team has:

• The feasibility of increasing inpatient rehabilitation duration by implementing an additional self-directed independent exercise program: My Therapy

• developed terms of reference for its committee

Research highlights

• prioritised research activity for 2016-17

During the past 12 months, our research activity has increased with growing numbers of clinicians engaged in patient-focused research activities. Ethics committee approvals of allied health research submissions has more than tripled in the past year, having grown from three newly-listed projects in 2014-2015 to 11 in 2015-2016.

These include projects with external partners and multi-disciplinary internal projects. The increase in research activity has contributed positively to the research knowledge-base among allied health staff and fostered a culture of critical enquiry. We have established protocols to mentor project-planning and research higher degree student enrolments, shepherd novice researchers through the research pathway, document progress for governance and reporting, and work with researchers to ensure outcomes and translation to improved clinical care are integral to project design.

• planned for sustained growth of the centre and impact on clinical care

• reviewed allied health research project activity • provided guidance where needed

A new Research Assistant position was created in June 2016 to support the centre’s operations, providing much needed administrative support to research functions.

Our work has impacts on patients, communities, carers and families at various phases of our research activity. We engage consumers in the design and recruitment phases and consumers benefit from the translation of findings into practice. For example, we recently completed a dietetics project led by Bek Anderson completed together with students of La Trobe University. In this project, the research lead and students investigated patient satisfaction and nutritional adequacy of the free fluids diet at Cabrini Malvern. The study found the free fluids diet (default meals, meals ordered and meals consumed) did not meet nutritional requirements for energy and protein compared with the referenced

population. Plate wastage (consumption) data revealed that patients met only 13-16 per cent of energy and 10-13 per cent of protein requirements. Sixty per cent of patients reported areas for improvement with food provision (that is, offering more flavours or more savoury options). Eighty per cent of patients were not offered a mid-meal snack. Forty per cent of patients did not receive explanations of their menu choices. These results led to recommendations and changes of services by improving nutritional adequacy and patient satisfaction of the free fluids diet by fortification of soups, offering mid-meal snacks (suitable for free fluids diet), and developing a free fluids menu for patients, in order to increase awareness of available/suitable options. The research team will now consider implementation of best practice guidelines to support early re-introduction of usual diet.

Future plans We plan to continue developing our strategic plan objectives of engagement with clinicians with research interest and develop research collaborations internally and externally. Emphasis will be placed on increased consultation in the research design stage of our projects to ensure the outcomes have maximum value.

Dissemination of knowledge from allied health staff who have completed research projects and attended conferences is a key factor and we will be working to strengthen and formalise strategies to reach more clinical staff. To support this, we aim to develop a higher level of engagement with university partners to maximise research support and collaboration potential. Achieving these objectives will enable us to meet our goals of capacity building, improve clinical outcomes, deliver high quality research output and provide high quality contributions to research culture.

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I N T E N S I V E C A R E U N IT

Our team of dedicated intensive care medical and nursing staff at Cabrini conduct both local and international research.

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From left: Dr Jonathan Barrett, Deb Sage, Dr Vineet Sarode and Shannon Simpson with Dr Deidre Murphy (right).

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Every patient admitted to our intensive care unit (ICU) at Cabrini Malvern (numbering more than 1500 annually), as well as those in other Victorian hospital ICUs, submit de-identified data to the adult patient database held by the Australian and New Zealand Intensive Care Society (ANZICS). This enables benchmarking of performance and research into current critical illness medical conditions and practices. Diligent data collection by our team supports this key activity.

Our involvement with the clinical trials group research at ANZICS has enabled us to participate in large international and multi-centre trials. This is an ongoing activity of our ICU and contributes to the wider intensive care community in working to develop and maintain best clinical practices in our specialty worldwide.

Primarily, research in our unit is designed to help Cabrini patients. We have focused our efforts on research topics that specifically target Cabrini’s intensive care patients (such as care of the cardiac surgery patient and end-of-life practices). Through our relationship with the wider intensive care research network within Australia and internationally, we are able to contribute to larger trials that directly improve the quality of intensive care medicine worldwide. This is helping to improve the overall standard of care within intensive care medicine.

We are extremely proud of this achievement, which will undoubtedly help patients and their families in the years ahead.

Research highlights

Future plans

Highlights of the ICU research program in 2015-16 were as follows:

The TRICS III and ETHICUS II trials will continue in 2016 and the new LabMET study will be starting soon. The LabMET study is a prospective observational study involving three major hospitals in Victoria and will test whether commonly measured laboratory variables can identify hospitalised patients who are at risk of major adverse events (death, unplanned ICU admission or activation of the rapid response team) before they occur. This may enable us to intervene sooner with patients before they become critically unwell.

• TRICS III (Transfusion Requirements in Cardiac Surgery) is an international, multicentre, randomised control trial that began in Canada and involves five major Victorian hospitals. This large, international trial aims to answer the question of when red blood cells should be transfused to patients undergoing open-heart surgery and whether the trigger for transfusion affects mortality and other important outcomes. So far, more than 3500 patients have been included in this trial worldwide. We began enrolling patients in this trial in June 2016, and aim to recruit 80 to 100 patients over the next 12 months.

• ETHICUS II is an international observational study that analyses current practices and attitudes towards endof-life care and associated issues within intensive care units. By June 2016, more than 30 Cabrini patients had been included. It is important to understand current practices for end-of-life care around the world, to document variations in the pattern of practice and to analyse the variables that might explain any observed differences in practice.

• The TRANSFUSE trial will determine whether transfusion of the freshest available blood makes a difference to the outcome of critically ill patients. Fifty Australian ICUs (and three overseas units) aim to enrol 5000 patients by December 2016. We completed our recruitment by late 2015, having recruited 60 patients in total to this trial.

The ANZICS clinical trials group point prevalence program will occur in 2016. This is an annual, voluntary, unfunded audit of ICU practice, to which we have contributed the past three consecutive years.

We are continually reviewing new research opportunities and aim to contribute to any studies that may be beneficial to Cabrini’s patient community.

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C LI N I C A L E D U C AT I O N

Cabrini is a strong supporter of education in healthcare, providing undergraduate and postgraduate education in medicine, nursing and allied health disciplines.

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From left: students E Juen Lee, Shin Hnin Wai, Tom Ponsonby and Eric Park; Dr Sara McKenzie; Dr Katie Walker (top); students Tom Lucarelli, Tina Zhou and Daniel Chan (bottom); and Haikal Abdullah Zain in the Stewardson Charitable Trusts Simulation Centre.

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Education department Nursing workforce In 2015-16, we aligned resources and activities to increase patient safety and support the developing workforce plan.

The primary outcome of our work was development and delivery of learning resources according to the specific needs of each ward across Cabrini’s clinical campuses.

This required the scoping of knowledge and skills for each ward and identification of a suitable form of delivery and assessment.

Integral to the delivery of targeted education has been the deployment of an online learning and assessment platform that enables education to be delivered to any nurse on any shift or even when they are away from a Cabrini site. Compared to the traditional model of clinical education that focuses on attendance at lectures and workshops, this new model allows staff to complete activities and case studies online. Night and weekend staff are now equally supported in clinical education and all staff are required to interact with the learning activities and provide evidence of their knowledge.

Quality and safety We trialled an ‘in-situ, just-in-time’ education model.

In-situ training has been adopted in other high-risk industries but has not been well explored in health. The model involved educators moving between wards to identify high-risk patients and provide the allocated nurse with education on mitigating the risk to the specific patient during that shift. The educators focused on clinical deterioration, medication safety, pressure injuries and falls. This model of teaching takes advantage of the context created by actual patients and provides targeted delivery of knowledge to protect the patient. The program identified common deficits of knowledge and skills that will now be addressed by widespread education.

Undergraduate placements Although Cabrini does not receive funding to support undergraduate places, the education department continued to provide undergraduate placements for nursing, allied health and medical staff. Clinical placements are an essential component of building a future workforce and more than 3000 placement days were provided for undergraduate nurses in 2015-16. To optimise the potential of clinical placements, the Cabrini Institute has formed a Nursing Clinical School with Australian Catholic University to provide extra workplace experiences and support for selected nursing students.

Students who apply to and are successful in gaining a position in the school will receive additional tuition from Cabrini nurses to prepare them for a successful transition into practice at Cabrini.

Cabrini-Monash Clinical School The Cabrini-Monash Clinical School has been an integral part of Cabrini for more than ten years. It is part of the greater Central Clinical School for Monash University.

Cabrini provides much needed clinical placements for students in the third, fourth and fifth years of Monash University’s Bachelor of Medicine and Bachelor of Surgery (MBBS) course. The students are well received across Cabrini hospitals. We have published research to support the informal feedback that we receive from patients and families. The presence of students in Cabrini hospitals supports positive working environments with an increased emphasis on scholarship and evidence-based practice.

Third-year program A total of 23 medical students spent their third year of study on clinical placements in various specialties of medicine and surgery at Cabrini Malvern. Their learning is complemented by integrated problem-based learning and simulation activities to enhance problem solving skills, reflective practice and procedural skills. Our

innovative program uses an e-technology platform to encourage individual engagement and self-directed learning, and students have provided excellent feedback on the program for every year that the program has been offered.

Students receive a weekly bedside teaching session delivered by one of our dedicated bedside tutors, as well as teaching sessions delivered by our specialist trainee program registrars. Supervision, feedback and assessment of students is undertaken by many clinical staff facilitating the achievement of competence and confidence by our students.

Fourth-year program Forty-one fourth-year students experienced a four-week paediatric rotation and were supervised by Dr Simon Costello.

Fifth-year program In the past 12 months, 91 fifth-year students completed a pre-intern experience at one or more of Cabrini’s campuses. The six-week placements occur in many medical specialties and general surgery. They offer students an opportunity to be part of the clinical team and contribute to patient care. This allows the student to understand what to expect of their transition into the workforce as an intern in the following year and to observe the role of the doctor in the healthcare system.

Fifth-year students participate in education and mentoring of the third-year cohort, which enables them to develop additional skills necessary for clinicians in the workplace.

Research The Cabrini-Monash Clinical School has successfully completed and published research on patient receptiveness to students and teaching program

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C LI N I C A L E D U C AT I O N evaluation. One project was completed by a medical student of our school who obtained the inaugural Education Summer Research Scholarship.

Allied health and ambulatory services education Internal activities In the allied health and ambulatory services education program, we have consolidated last year’s initiatives and begun new ones. In our 2015-16 plan, we focused on four goals: • to encourage, enable and support clinical staff professional development

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• to provide high-quality student placements to ensure work ready allied health assistants and allied health professionals • to develop future health service leaders • to host formal AHP professional development activities These goals have guided initiatives across allied health and ambulatory services education including establishment of an education working party, establishment of a process to support staff education and streamlining of mandatory training. Establishment of an education working party enabled greater communication and input from each of our departments, and helped us to identify areas for focus at the department level such as • orientation and mandatory training • information technology • Cabrini’s patient administration system known as PAS and VicPlace (a secure, web-based information system to assist clinical placement providers to plan and administer clinical placements with their education provider partners) • clinical teaching and training • academic teaching and training • staff education

Establishment of a process to support staff education has involved a service-wide system to approve, record and report all supported staff education activity, inclusive of study leave, financial support and capturing participation in higher qualifications.

Streamlining of mandatory training has focused on consistency between allied health and ambulatory services departments and the clinical education department, including staff mandatory training via Cabrini’s learning-management system, as well as recent student and staff access to Cabrini’s clinical eLearning space known as CELS. Consolidation of last year’s initiatives included continuation of the senior allied health and ambulatory services professional development program, which received strong attendance and positive feedback from participants and from leaders who have facilitated the sessions. Our allied health and ambulatory services staff continued to participate in Cabrini-led professional development programs that were previously targeted to nursing staff, now focusing on the multidisciplinary team.

External activities Our allied health department has sustained strong relationships with La Trobe University and Holmesglen Institute of TAFE, currently hosting almost 3000 allied health professional student placement days per year and 150 allied health assistant Certificate IV placements days per year. Allied health professional staff continue to embrace the role of academic clinician, providing teaching to undergraduate physiotherapy and dietetics students at La Trobe University. Similarly, allied health assistant staff continue to embrace the role of adjunct teacher, providing teaching to students at Holmesglen Institute of TAFE.

Specialist trainee program In 2015-16, Cabrini Institute supported 87 specialist trainees across 15 different specialties (anaesthetics, emergency medicine, gastroenterology, general medicine, geriatrics, haematology, intensive care, medical administration, medical oncology, neurology, palliative care, pathology, upper-gastrointestinal surgery and colorectal surgery). The trainees’ experiences at Cabrini give them insights into private medicine, working with health funds and different patient populations. For example, haematology registrars report that they see more non-malignant haematology at Cabrini than in the public sector.

In February 2016, we discontinued our participation in the specialist training program (STP) surgical program due to changes implemented to the surgical training program and our respect for the integrity of the relationship between our patients and their surgeon of choice. We could not provide enough ‘primary cutting’ experience for this group of surgical trainees. Cabrini has been involved in the program since its inception and is grateful to the surgeons who have taught and supported the trainees over many years.

There are approximately 900 trainees in the Federal Government’s STP. Current funding arrangements cease in February 2017 and we await advice on whether the program will be funded after that time.

University of Notre Dame Our second year of regular clinical placements for final year undergraduate medical students from the University of Notre Dame have continued in cardiology; obstetrics and gynaecology; and orthopaedic surgery/ rehabilitation. These students rotate every four weeks. We are grateful to the clinicians who support this education program. Some students have engaged in research with Associate Professor Natasha Michael. We welcome their involvement in the wider activities of Cabrini Institute.

Following in her mother’s footsteps A suggestion from her mum to follow in her footsteps has led to a career Amanda Peat never dreamed of.

Now Cabrini’s Advanced Care Educator and Simulation Educator, it was only 15 years ago that Amanda did not know just what life had in store for her. “I never knew what I wanted to do,” she said. “In high school, I enjoyed biology and all the health subjects and I love people and talking. My mum actually suggested it (nursing); she was a nurse in the army at the time, and I’ve never looked back.

She works at Cabrini too, as a lifestyle coordinator.”

In 2007, Amanda worked as a personal care attendant at Cabrini Residential Aged Care in Ashwood for 12 months while studying. The following year, she started at Cabrini as a registered nurse before moving into the education department in 2013. She took on the role of Advanced Care Educator in October 2014 and loves the challenges and learning involved.

“I’m involved in educating people within the advanced care areas of Cabrini including ICU the catheterisation laboratory and cardiac areas,” she said. “It’s a little bit of everything.”

Amanda, 30, shares the role of Simulation Educator, which she says includes the designing and running of stimulation programs at Cabrini. “We have medical students, nursing

students, medical and nursing staff who come through the Stewardson Charitable Trusts Simulation Centre and we design programs that provide an opportunity for hands-on practice and learning while maintaining and improving patient safety. We use a lot of different technologies and teaching modalities.”

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For Amanda, her passion for education and her love of teaching are highlights of her job. “The most rewarding moment is the ‘a-ha’ moment, when something we’ve been working on with the learners finally clicks – it’s exhilarating and exciting, also it’s the influence we can have on improving patient care and safety,” Amanda said.

She says the most challenging aspect of her role is that of developing new education programs. “It can be quite challenging to come up with new ways of engaging with our learners,” said Amanda. “But I personally find it an exciting challenge.”

Thinking about her future, Amanda says she quite simply loves Cabrini and does not see herself going anywhere else. “I love everything Cabrini stands for,” she said. “I’ve been really lucky to be involved in a lot of research within my role, which positively impacts patient care and safety and that has even reached out into the community. I’m proud to be part of the education department, we are doing some really interesting, new and exciting work.”

S T E WA R D S O N C H A R I TA B LE T R U S T S S I M U L AT I O N C E N T R E

Simulation at Cabrini has four main purposes – education, assessment, research and improving patient safety – providing a bridge between theory and real-life clinical experience.

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From left: Matt Johnston, Dr Katie Walker, Matthew Peck (top), the hand of a manikin (bottom) and Sr Pietrina Raccuglia MSC (left) with Andrew Driver.

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The Stewardson Charitable Trusts Simulation Centre is located at Cabrini’s Patricia Peck Education and Research Precinct in Malvern. Essentially, we use simulation to ‘copy’ one or more aspects of the real clinical environment, so that we can interact in a ‘pretend world’, which mimics the hospital environment. Simulation at Cabrini has four main purposes – education, assessment, research and improving patient safety – providing a bridge between theory and real-life clinical experience.

Simulations may be simple or extremely complex depending on the comfort of the learners, the facilitator’s experience and the skill, behaviour or system being simulated. Every simulation is different. The one thing they all have in common is that every simulation at Cabrini is used as a bridge between theory and real-life clinical experience.

Wide range of programs In 2015-16, we have held various programs in the Stewardson Charitable Trusts Simulation Centre including: • medical management in rural settings • patient care and assessment in graduate nurses and midwives • dementia and delirium training • managing challenging behaviours • interdisciplinary assessment and management of stroke • basic and advanced life support (babies, children and adults) • advanced airway management • response to cardiac and respiratory deterioration • team training and case-based training for medical students.

Importantly, we have used the centre to test new assessment tools and systems before we implement them in the clinical environment.

We use a range of different techniques in simulation.

These may include role plays, fake body parts, full manikins (dummies) that can mimic patients to some degree and occasionally we hire actors to play the role of patient. We are fortunate to have such a diverse range of manikins available for our use in teaching and learning including adults, children and infant models. They are highly versatile in that they may be fully programmed and can display a wide range of physiological signs, including heart and breath sounds. They can be intubated, ventilated, defibrillated and cannulated.

Arrival of SimMom and baby The most recent addition to our set of manikins, SimMom, is a birthing simulator. SimMom was made available by a generous donation and is a full-term pregnant woman. She has the correct anatomy and is able to accurately simulate a wide range of situations that may be encountered during childbirth. This manikin comes with a full-term newborn baby. SimMom is being used to assist midwifery and obstetric staff at Cabrini to practise a range of situations, from normal births to life-threatening situations. Being able to recognise and respond quickly to these situations during childbirth can mean the difference between life and death, for both mothers and babies.

We use a variety of training equipment to simulate various skills. We offer training days in the Stewardson Charitable Trusts Simulation Centre and offer equipment for borrowing and use in training conducted in Cabrini’s hospital wards. Our equipment includes basic life support manikins, intravenous cannulation arms, lumber puncture trainers, pelvic trainers with interchangeable inserts, catheter trainers, difficult airway trainers, suture trainers and a monitor that can be used to display preprogrammed observations, cardiac rhythms or maternity traces. These are all used so that staff can practise and hone their skills safely, without risk to a patient.

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LE E & B R I A N J O H N S TO N E LI B R A RY

The Lee & Brian Johnstone Library is an integral part of education and research at Cabrini.

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From left: Donor Brian Johnstone, librarian Di Horrigan, signage at the library and Jennifer Burden.

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The Lee & Brian Johnstone Library at Cabrini has transformed itself into an e-library providing for the research and study needs of Cabrini now and in the future.

The focus areas of the library are: • Accessibility of evidence-based, high quality resources to all staff, 24 hours • Increased marketing of library resources and services available to all Cabrini sites • Provision of expert searching of information to all research, quality and education staff at the Cabrini’s Patricia Peck Education and Research Precinct In January 2015, we began offering remote electronic access to all subscribed resources through the OpenAthens software (an information portal). This enables Cabrini staff and accredited medical practitioners in any location with 24-hour access to information for research, education, quality and clinical questions, in order to provide better patient care. By May 2016, 500 staff had registered to use this facility. Remote availability of library resources has brought about increased use by accredited medical practitioners at Cabrini. There were 42,151 searches of databases and eBooks in 2015-16, an increase of 76 per cent on the previous year. Cabrini Institute and research staff increased their access to our library’s resources by 62 per cent in 2015. Librarian Di Horrigan has been integral in providing expert literature searching for research activities and was co-author of an article accepted by the Health Inform Journal in 2016 titled ‘More for our dollar – providing value with consortium buying through VHLC’.

Projects • Library Pathways @ Prahran was piloted in 2015, to provide formal face-to-face contact with library staff to discuss projects, information needs and informal learning of literature searching skills. An evaluation of this project demonstrated more engagement and usage of resources and services by staff at Cabrini Palliative Care in Prahran. The project was rolled out to Cabrini Brighton in 2016 and continues at our Prahran hospital.

• The ‘Beginning Research’ LibGuide was launched at Cabrini Research Day in October 2015 to educate the novice researcher on how to start a research project and provide access to resources in statistical analysis, critical appraisal and evaluation of research • Formal teaching of topics in ‘Searching the Medical Literature’ and ‘Critical Appraisal of Journal Articles’ have been provided to Monash University medical students and allied health staff We have been fortunate to have received donated funding from the Lee & Brian Johnstone Fund. This has allowed us to subscribe to the resource Clinical Key over three years. Without such generosity, we would not be able to subscribe to such products, and still maintain a core collection of resources.

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Grants and scholarships During 2015-16, the Cabrini Institute administered more than $430,000 in grant funding. The funding supported staff professional development and education, as well as clinical research and quality improvement projects. The generosity of donors and the support of the Cabrini Foundation has contributed to Cabrini making many improvements and advancements in many areas of healthcare.

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Education Cabrini supports the professional development of its staff through the education grant rounds. In 2015-16, nurses, educators and staff from physiotherapy, pharmacy, speech pathology and Cabrini Pathology departments succeeded in securing funding to support their postgraduate studies and other professional blood bank development learning programs.

Two high performing nurses embarked on once-in-alifetime palliative care tours of Asia. Another attended a palliative care conference in Montreal, Canada, and participated in an observership program at a premier cancer centre in Toronto. These nurses conducted benchmarking, information gathering and knowledge sharing with their international colleagues about improving advance care planning, palliative goals, cultural sensitivity, and the patient/family experience during death and dying. A plan for dissemination of this knowledge is underway.

Travel grants The Medical Staff Committee funds a travel grants scheme for non-medical, clinical Cabrini staff to attend and present at domestic or international conferences.

In 2015-16, the travel fund supported Dr Tash Brusco, Cabrini’s chief physiotherapist, to present at the Health Economics Congress in Italy, and Dr Amber Mills, a research fellow with the Cabrini Monash University Department of Medicine, to present at a conference on advance-care planning and end-of-life care in Munich, Germany. In Australia, allied health clinicians, as well as with emergency, orthopaedic, hospital-in-the-home and urology nurses, promoted their research and quality improvement projects at various national conferences.

Medical student research and outreach In 2016, the Medical Staff Committee funded five medical student projects; a significant increase in funding on previous years. Supported research projects included: • Education Programs – evaluation and recommendations • Patient outcomes following MET attendance that result in do-not-resuscitate • Reported cognition: A novel modification of the Reported Edmonton Frail Scale The Medical Staff Committee sponsored Kellie Hu, a thirdyear medical student, to work alongside orthopaedic surgeon Mr John Griffith in Medang Papua New Guinea.

The support enabled Ms Hu to experience medicine in a developing country, observe local theatre lists and engage with local medical students.

Cabrini Foundation clinical research and quality improvement grant round The annual Cabrini Foundation Grant round was introduced in 2015 to provide a program for Cabrini staff and accredited medical practitioners to apply for funding for research or quality improvement activities. The 2016 round was boosted by $146,000 in special project funding additional to the $150,000 in research grants and quality improvement grants offered annually. The special project funding included a $30,000 grant to commemorate 2016 as the twentieth anniversary of the Cabrini Institute. It was awarded to Clara Officer (Nurse Manager) and Kelly Sherman (Clinical Nurse Specialist and Associate Nurse Manager) for their research project ‘Informing an autismfriendly Children’s Centre at Cabrini’.

The $100,000 John Sutherland Hamling Breast Cancer Research Grant was awarded to Associate Professor Gary Richardson for his project on energy restriction for weight loss in women receiving chemotherapy.

The $16,000 Grace Saunders Rheumatology Research Grant was awarded to Dr Susan Slade for her kneearthroscopy decision tool project. Further, $30,000 clinical research grants were awarded to Associate Professor Michele Levinson, Dr Ryan Hodges, Dr Clare O’Callaghan and Associate Professor Tony Goldschlager.

A $15,000 quality improvement grant was awarded to Mr Troy Keith.

PADDI trial The generosity of donor sponsorship and the support of research by the Cabrini Foundation has made it possible for Cabrini Institute to participate in the perioperative administration of dexamethasone and infection clinical trial, known as PADDI. The funds enabled the Cabrini Institute to recruit trial coordinator Nina Box in February 2016, in order to coordinate the PADDI trial and undertake essential start-up activities. The team of Principal Investigator Dr Antonio Grossi, research manager Dr Emma Baker and Nina Box established the trial and engaged multiple departments.

PADDI is a first for the Cabrini Institute: it is the first anaesthetics trial to be undertaken and the first venture beyond our successful oncology clinical trials program. Partnering with the Alfred Hospital and joining multiple hospitals in Australia and New Zealand, the trial will examine whether the administration of dexamethasone to prevent nausea and vomiting in people undergoing surgery increases the risk of infection, especially in diabetic patients. Surgical infections are a complication in up to 12 per cent of surgeries and result in longer hospital stays and billions of dollars in increased health costs. It is estimated that more than 60 per cent of patients undergoing surgery currently receive dexamethasone, despite not knowing all of its potential effects. The PADDI trial will inform best surgical care of patients. Recruitment for subjects for this trial is scheduled to begin in July 2016.

Gratitude The scholarships and grants program would not be possible without the great generosity and foresight of Cabrini’s donors. We extend our immense gratitude to our long-standing donors and those who have recently joined us to make the following grants and funding available: • Allison Monkhouse Palliative Care Scholarship (Ian Allison) • Brendon Finnegan Professional Development Grant (Caryl Finnegan, Sarah Reilly) • Brian Gillies Palliative Nursing Travel Scholarship (Prue Gillies AM) • Brian J Sutton Nursing Scholarship (Brian J Sutton) • Chan Palliative Education Scholarship • Heartbeat Cabrini Cardiac Nursing Scholarship (Bruce Hocking, Ron Weinmann) • Jean St Leger Nursing Education Awards (Lawry and Pam St Leger) • Jeffrey and Violet Loewenstein Cardiac Grant (Jeffrey and Violet Loewenstein) • Joyce Reed Memorial Grant (Ray Reed) • Lorraine McClymont Oncology Nursing Scholarship (Graeme McClymont) • Peter Meese Study/Travel Grant and Oncology Nursing Research Grant (Dr Darren Lockie) • Ron and Joan Davies Memorial Fund (Sue Davies) • Sarah Jane Merl Miskin Palliative Care Nursing Scholarship (Ben Miskin) • Sasse Scholarship (Dr Jenneth Sasse) • Vena Florence Fryer Medical Nursing Scholarship (Glenn Fryer, Peter Dunn) • Medical Staff Committee (Chair – Dr Antonio Grossi) • Cardiac Conference Fund (Chair – Dr James Shaw) • Grace Saunders Rheumatology Grant • John Sutherland Hamling Breast Cancer Research Grant

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Department staff

MONASH DEPARTMENT OF CLINICAL EPIDEMIOLOGY AT CABRINI HOSPITAL Head of Department Professor Rachelle Buchbinder Managing Editor, Cochrane Musculoskeletal Group Dr Renea Johnston Biostatistician Dr Margaret Staples ARAD State Coordinator Joan McPhee Research Fellow Dr Allison Macpherson

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Postdoctoral Research Fellow Dr Susan Slade Administrative Assistant Cathy Matthews PhD students Megan Blackburn (2010- ), Deakin University Sarah Hosking (2014- ), Deakin University Rebecca Jessup (2014- ), Deakin University Dr Bethan Richards (2011- ), University of Sydney Master student Kelly Joyce (2014- ), Monash University

CABRINI MONASH DEPARTMENT OF MEDICAL ONCOLOGY THE SZALMUK FAMILY DEPARTMENT OF MEDICAL ONCOLOGY Head of Department Associate Professor Gary Richardson Principal Investigators Dr Yoland Antill Dr Ben Brady Dr Andrew Haydon Dr Melita Keneally Associate Professor Lara Lipton Professor Miles Prince Associate Professor Jeremy Shapiro Dr Michelle White Associate Investigators Dr Emma Beadsley Dr Sanjeev Gil Associate Professor Ian Haines Dr Henry Januszewicz Dr Esther Lin Dr Ben Markman Miss Joanna Morgan Dr David Pook Dr Nicole Potasz Dr Tess Schenberg Professor Max Schwarz Dr Robert Stanley Dr Karen Taylor Associate Professor Max Wolff Research Manager Dr Emma Baker Jasmine Kopcewicz (Research Administration)

Study Coordinators Dr Demis Balamatsias Nina Box Julia Carlson Kate Hurford Mary Lane Connie Louizos Alice Newman Helen Smenda Suven Subasinghe Tatiana Woellner Cancer 2015 Jenny MacIndoe Rachel Osborne Cancer Trials Australia Adeeba Aziz Anger Abiel Cabrini Family Cancer Clinic Dr Lynne McKay Brightways Breast Cancer Program Vicky Durston (Manager) Barbara Scher (Data Manager) CABRINI MONASH UNIVERSITY DEPARTMENT OF MEDICINE Head of Department Associate Professor Michele Levinson Research Fellow Dr Amber Mills Research Assistants Anthea Gellie Natalie Heriot Georgina Johnstone Gaya Sritharan

CENTRE FOR ALLIED HEALTH RESEARCH AND EDUCATION Head of Department Associate Professor Helena Frawley Honorary Researchers Dr Tash Brusco Dr Rosemary Higgins Professor Catherine Itsiopoulos Research Assistant Sophie Jennings Research Associates Carolyn Cracknell Anne-Marie Damatopoulos Sarah Foster Lillian Krikheli Helen Kugler Kuan-Yin Lin Matthew Macaulay Douglas McCaskie Hema Navaratnam Jacqueline Raymond Louise Tilley Yvette Vonier Jason Wallis

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SZALMUK FAMILY PSYCHO-ONCOLOGY RESEARCH UNIT Head of Unit Dr Sue Burney (until January 2016) after which Dr Jo Brooker (Research Fellow) provided leadership Research Assistant Tanya Osicka Honorary Researchers Dr Sue Burney Jane Fletcher Courtney Hempton Professor David Kissane

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Research Students Shey Cooper, Postgraduate Diploma of Psychology, Deakin University Parris Davenport, Psychology Honours, Deakin University Lebecca Jelicic, Master of Counselling Psychology, La Trobe University Melissa Maas, Doctor of Psychology (Health), Deakin University Sophie Robinson, Doctor of Psychology (Clinical), Monash University Gemma Stephenson, Master of Clinical Psychology, Victoria University Clinical Placement Students Samantha Finan, Doctor of Psychology (Clinical), Monash University Lebecca Jelicic, Master of Counselling Psychology, La Trobe University Paulina Mech, Doctor of Psychology (Health), Deakin University Sherianne Wong, Master of Clinical Psychology, Australian Catholic University

CENTRE FOR NURSING RESEARCH Head of Department Professor Leanne Boyd

PALLIATIVE CARE RESEARCH UNIT Head of Department Associate Professor Natasha Michael

Research Associate Amanda Pereira-Salgado

Senior Research Associate Associate Professor Clare O’Callaghan

Research Assistant Patrick Mader

Palliative Physician Dr Merlina Sulistio

PhD Students Louise Alexander, Deakin University Janet Curtis, Monash University Grainne Lowe, Monash University Tegwyn McManamny, Monash University Sue Wiley, Monash University Diana Wong, Monash University

CABRINI MONASH UNIVERSITY DEPARTMENT OF SURGERY FRÖHLICH WEST CHAIR OF SURGERY Head of Department Associate Professor Paul McMurrick

INTENSIVE CARE UNIT Director Dr Vineet Sarode Deputy Directors with responsibility for research Dr Jonathan Barrett Dr David Brewster Specialist Physicians Dr Steve Philpot Dr Ben Turner

Consulting Surgeons Mr Stephen Bell Mr Peter Carne Mr Martin Chin Mr Chip Farmer Emeritus Professor Adrian Polglase Mr Pravin Ranchod Mr Paul Simpson Research Fellow Dr Simon Wilkins Database Manager Karen Oliva

Research Coordinators Gabrielle Hanlon Shannon Simpson

LBBC Administration Matthew Holmes

Nurse Unit Manager Deb Sage

ANAESTHETICS RESEARCH PADDI Trial Coordinator Nina Box

INSTITUTE DATA MANAGEMENT Angela Baxter Natalie Heriot Rebecca Khampha Jennifer MacIndoe Mr Gilbert Shardey EDUCATION DEPARTMENT Director Matt Johnson Simulation Centre Amanda Peat Tanya Warren Academic Coordinator Geoff White Placement Facilitators Anna Marie Asa Moya Beattie Helen Fountain Marina Necoski Jodie Patrick Simsy PeterPalackal Ranjana Pokhrel Andrew Talbot Clinical Education Team Anne Carolan Kate Cook Madeleine Cosgrave Scott Dickson Abby Falla Yvette Gomez Claire Hatherley Natalie Horvath Barbara Miles Joanne Miller

Steven Musgrave Emma Patterson Rick Peebles Christine Quinn Jordana Schlieff Elizabeth Smith Louise Suttie Louise Vautin Lauren Williams CABRINI-MONASH CLINICAL SCHOOL Clinical Dean Associate Professor Michele Levinson Clinical Site Administrator Jennie McInerney Tutors Dr Yoland Antill Dr Jonathan Barrett Mr Ash Chehata Dr Chris Yeo Simulation Dr Diane Kelly Dr Krisoula Zahariou Problem Based Learning Dr Christine Jackman Dr Sara Mackenzie

CABRINI INSTITUTE INFRASTRUCTURE TEAM Director of Institute Infrastructure Anne Spence Staff Dr Emma Baker (Manager, Research Programs) Anne-Marie Devine Jasmine Kopcewicz Janine La’Brooy Jan Palich Carrie Robertson Sue Smith Maria Terzoglou Michele Tonkin LEE & BRIAN JOHNSTONE CABRINI LIBRARY Manager of Library Services Di Horrigan CABRINI HUMAN RESEARCH ETHICS COMMITTEE Manager, Committee and Research Governance Jennifer Burden Committee Administrator Grace Wijnen Administrative Assistant Sue Smith

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GOVER NING SAFE AND E THIC AL R E S E ARC H

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Cabrini Human Research Ethics Committee The Cabrini Human Research Ethics Committee helps to protect the interests of patients, researchers and Cabrini by maintaining high ethical research standards across all research projects and all levels of risk.

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The committee reports directly to the Cabrini Board and is responsible for reviewing and approving all research projects conducted at Cabrini that involve human participants. This committee ensures that: • Ethically sound research is promoted and conducted at Cabrini • The research affirms the mission and values of Cabrini and social teachings of the Catholic Church • Ethical standards are maintained in research projects to protect the interests of the research participants, the investigator and the institution.

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The committee approved almost 100 projects during 2015-16, representing a wide range of research areas.

Currently we have more than 1171 projects in our database. The number of projects submitted for low and/or governance review increased while there was a reduction in the number of projects submitted for full review. The number and diversity of the low-risk applications highlights the broad involvement of Cabrini staff in research and quality assurance projects. We are continuing to work on developing our database with a view to moving to electronic submission of applications for all levels of review.

Our committee continues to be led by Dr Margaret Staples. We have had a number of changes to the committee this year: we welcomed Jeffery Gleeson QC, Associate Professor Helena Frawley and Amanda PereiraSalgado. Dr Gordon Donaldson AM and Nir Bruner were appointed on 1 July 2016. The committee farewelled Angela Baird, David Curtain QC, John Robertson and Dr Joanne Brooker as members.

The 2016 Twilight Seminar took place on 6 September 2016.

Simon Windsor from Bellberry Limited (a national, private not-for-profit organisation that provides scientific and ethical review of human research projects) was the guest speaker. He presented on the development and roll-out of the national patient information and consent form.

C A B R I N I H U M A N R E S E A RC H E T H I C S COM M IT T E E NAME

NHMRC CATEGORY

GENDER

STATUS

Angela Baird

Nurse

Female

Finished 01/09/14

Beatrice Bastomsky

Layperson – female

Female

Michelle Britbart QC

Lawyer

Female

Dr Joanne Brooker

Researcher

Female

Jennifer Burden

Invitee

Female

David Curtain QC

Lawyer

Male

Associate Professor Henry Debinski

Researcher

Male

Associate Professor Helena Frawley

Researcher

Female

Started 01/06/16

Jeffrey Gleeson QC

Lawyer

Male

Started 27/11/15

Dr Dane Horsfall

Professional carer

Male

Revd Kevin McGovern

Pastoral carer

Male

Amanda Pereira-Salgado

Researcher

Female

Associate Professor Marilyn Poole

Researcher

Female

John Robertson

Layperson – male

Male

Dr Margaret Staples

Chairperson

Female

Associate Professor Val Usatoff

Researcher

Male

Dr Sharon Woolf

Professional carer

Female

Finished 30/06/16 51

Finished 30/11/15

Started 01/06/16

Finished 31/03/16

C A B R I N I H U M A N R E S E A RC H E T H I C S COM M IT T E E

RESEARCH AREA

PROJECT

PRINCIPAL RESEARCHER

ALLIED HEALTH

The feasibility of increasing inpatient rehabilitation duration by implementing an additional self-directed independent exercise program, My Therapy

Louise Tilley

Implementation of stroke clinical practice guidelines at Cabrini

Dr Tash Brusco

Threshold concepts, ways of thinking and practising and curriculum: a phenomenological heuristic research inquiry in an entry-level physiotherapy context

Jan Tepper

ANAESTHETICS

The perioperative administration of Dexamethasone and infection

Dr Antonio Grossi

CARDIOLOGY

Basic life support training for patients and their family members at cardiac rehabilitation: A feasibility study

Dr Dion Stub

COlchicine in patients who have acute coronary syndromes – the COPS trial

Dr Jonathon Habersberger

Exploring the link between alcohol and atrial fibrillation recurrence: a multicenter, randomised controlled trial (ETOH-AF)

Professor Peter Kistler

Improving success rates of direct cardioversion for atrial fibrillation in patients with an elevated body mass index: a randomised controlled trial of adhesive patches versus hand-held paddles (DCR-BMI)

Professor Peter Kistler

The Dormant-AF study: Determining the optimal dose of adenosine for unmasking dormant pulmonary vein conduction in patients undergoing AF ablation

Professor Peter Kistler

Jejunal versus oral nutrition support for one month after discharge from hospital following oesophagectomy or total gastrectomy – a randomised controlled trial

Dr Mariagrazia De Luca

Finger food menu proposal (patient satisfaction survey)

Rebekah Anderson

Investigating patient satisfaction and nutritional adequacy of the free fluids diet at Cabrini Malvern

Rebekah Anderson

Augmented eXperience Modules (AXM) activity

Associate Professor Michele Levinson

Evaluation of a male catheterisation program

Associate Professor Michele Levinson

Evaluation of the fifth-year mentoring and teaching program

Associate Professor Michele Levinson

Self-perceived readiness to practice of graduate and experienced nurses entering perioperative education

Matthew Johnson

Rapid rule-out of acute coronary syndrome

Dr Dane Horsfall

Volunteer peer telephone support for older people to improve quality of life after discharge from the emergency department – Hospitals and patients working together in unity (How R U?)

Dr Debra O’Brien

Cabrini emergency department scribe project – piloting training Australian scribes

Dr Katie Walker

Patient experiences towards medical scribes in an Australian emergency department

Lachlan Hegarty

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DIETETICS

EDUCATION

EMERGENCY MEDICINE

RESEARCH AREA

PROJECT

PRINCIPAL RESEARCHER

EMERGENCY MEDICINE CONTINUED

Physician attitudes towards, and experiences with, the implementation of a scribe program in an Australian emergency department

Timothy Cowan

Patient tolerance of medical scribes in the Emergency Department: a qualitative approach

William Dunlop

Cabrini analgesia and pain project for the emergency department

Claire Hatherley

The online resource for religious and cultural advance care planning

Associate Professor Leanne Boyd

Comprehension of advance care planning terminology in people with cancer

Dr Natasha Michael

A combined phase two to three, double-blind, randomised, placebo-controlled induction and maintenance study evaluating the safety and efficacy of GS-5745 in subjects with moderately to severely active ulcerative colitis [GS-US-326-1100]

Associate Professor Henry Debinski

A phase three, multicenter, randomised, double-blind, placebo-controlled trial of oral RPC1063 as induction and maintenance therapy for moderate to severe ulcerative colitis (RECEPTOS)

Associate Professor Henry Debinski

A phase three, randomised, double-blind, placebo-controlled, multicentre study to evaluate the efficacy and safety of etrolizumab as an induction and maintenance treatment for patients with moderately to severely active Crohn’s disease [GA29144]

Associate Professor Henry Debinski

A phase three, randomised, double-blind, placebo-controlled, multicentre, parallel group study to assess the efficacy and safety of fixed-dose combination RHB-104 in subjects with moderately to severely active Crohn’s disease [RHB-104-01]

Associate Professor Henry Debinski

A randomised, double-blind, double-dummy, multicentre, active-controlled study to evaluate the efficacy and safety of Vedolizumab IV compared to Adalimumab SC in subjects who have ulcerative colitis [MLN0002-3026]

Associate Professor Henry Debinski

An open-label extension and safety monitoring study of patients with moderately to severely active Crohn’s disease previously enrolled in the Etrolizumab phase three protocol GA29144. [GA29145]

Associate Professor Henry Debinski

Evaluation of person-centred model of dementia care

Dr Constantine Tsingas

A novel modification of the reported edmonton frail scale (REFS)

Dr Michael Rose

Predicting delay in complex discharge: why stay longer?

Dr Michael Rose

HEALTH ECONOMICS

An evaluation of multiple financially driven projects run in parallel across a private health service. The Advisory Board projects.

Dr Tash Brusco

INFECTIOUS DISEASES

Parents’ immunisation needs and attitudes – Antenatal: a survey

Dr Margie Danchin

END OF LIFE

GASTROENTEROLOGY

GERIATRIC MEDICINE

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C A B R I N I H U M A N R E S E A RC H E T H I C S COM M IT T E E

RESEARCH AREA

PROJECT

PRINCIPAL RESEARCHER

INTENSIVE CARE

TRICS III: Transfusion requirements in cardiac surgery – an interventional, multicentre, randomised, controlled trial to assess transfusion thresholds in patients undergoing cardiac surgery

Dr David Brewster

NEUROLOGY

Brain status and recovery: the ocular motor system as a surrogate marker of motor and cognitive recovery post ischaemic stroke

Dr Owen White

Melanopsin projection responses in neurological diseases associated with fatigue and sleep orders

Dr Owen White

Review of concussion and video analysis in Australian football

Mr Gavin Davis

Interdisciplinary heath team’s experience in mobilising postoperative orthopaedic patients who have altered mental status in a private hospital setting: a phenomenological study

Jovie Ann Decoyna

A point prevalence study of peripheral intravenous cannulation and therapy at Cabrini Malvern and Brighton and St John of God Hospital, Subiaco

Associate Professor Leanne Boyd

Alcohol use in pregnancy and the national maternity data development project: What do maternity clinicians think?

Professor Jane Halliday

Alcohol use in pregnancy and the national maternity data development project: What do maternity clinicians think?

Professor Jane Halliday

A phase 1A/1B, open-label, multiple-dose, dose escalation and expansion study to investigate the safety, pharmacokinetics and antitumor activities of the anti-PD-1 monoclonal antibody BGB- A317 in subjects who have advanced tumours

Associate Professor Gary Richardson

A phase 1A/1B, open-label, multi-dose, dose escalation and expansion study to investigate the safety, pharmacokinetics and preliminary antitumor activities of the B-RAF inhibitor BGB-283 in subjects who have solid tumors

Associate Professor Gary Richardson

A phase three, open-label, multicentre, randomised study evaluating the efficacy and safety of MPDL3280A (Anti-PD-L1 Antibody) in combination with Carboplatin + Paclitaxel or MPDL3280A in combination with Carboplatin + Nab-Paclitaxel versus Carboplatin + Nab-Paclitaxel in chemotherapy-naive patients with stage 4 squamous non-small cell lung cancer [GO29437]

Associate Professor Gary Richardson

A phase three, multicenter, randomised, open-label study of avelumab (MSB0010718C) alone or in combination with pegylated Liposomal Doxorubicin versus pegylated Liposomal Doxorubicin alone in patients who have Platinum-resistant/refractory ovarian cancer (Javelin Ovarian 200) [B9991009]

Associate Professor Gary Richardson

A phase three, open-label, randomised study to investigate the efficacy and safety of Atezolizumab (AntiPD-L1 Antibody) compared with best supportive care following adjuvant cisplatin-based chemotherapy in PD-L1 selected patients with completely resected stage IB-IIIA non-small cell lung cancer [GO29527]

Associate Professor Gary Richardson

NURSING

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OBSTETRICS

ONCOLOGY AND HAEMATOLOGY

RESEARCH AREA

PROJECT

PRINCIPAL RESEARCHER

ONCOLOGY AND HAEMATOLOGY CONTINUED

A phase three, open-label, randomised study of MPDL3280A (Anti-PD-L1 Antibody) in combination with carboplatin + paclitaxel with or without bevacizumab compared with carboplatin + paclitaxel + bevacizumab in chemotherapy-naive patients with stage four non-squamous non-small cell lung cancer [GO29436]

Associate Professor Gary Richardson

KEYNOTE 100: A phase two, open-label, single-arm, multicentre study to evaluate efficacy and safety of pembrolizumab monotherapy in subjects who have advanced recurrent ovarian cancer

Associate Professor Gary Richardson

Thrivor – an investigation into the challenges of living with cancer beyond the patient’s clinical care

Associate Professor Gary Richardson

Palliative chemotherapy within the last 30 days of life: experience at a private hospital oncology unit

Associate Professor Ian Haines

Phase three, randomised, open label, multicenter, controlled study of Galeterone compared to Enzalutamide in men expressing androgen receptor splice variant7 mRNA (ARV7) metastatic (M1) castrate resistant prostate cancer (CRPC)

Associate Professor Jeremy Shapiro

Randomised, phase two trial evaluating Pharmacokinetics and safety of four Ramucirumab dosing regimens in second -line gastric or gastroesophageal junction Adenocarcinoma [14T-MC- JVDB]

Associate Professor Lara Lipton

Clinical trial of nivolumab (BMS-936558) combined with ipilimumab followed by nivolumab monotherapy as first-line therapy of subjects who have histologically confirmed stage III (unresectable) or stage four melanoma [CA209401]

Dr Ben Brady

Assessing general practitioner involvement in cancer care from diagnosis to advanced illness

Dr Catherine Rowe

Changing lanes: real-time chemotherapy switching in advanced prostate cancer

Dr David Pook

Retrospective audit of non-surgical heamato-oncology patients admitted to ICU and their outcomes

Dr Hieu Chau

A phase two, randomised, double-blind, placebo-controlled study of Azacitidine with or without Birinapant with a single arm open-label run-in phasein subjects with higher risk Myelodysplastic syndrome or chronic Myelomonocytic leukaemia

Dr Melita Kenealy

To assess the efficacy and safety of dose reduced fludarabine, cyclophosphamide and rituximab in elderly patients with chronic lymphocyte leukaemia

Dr Melita Kenealy

A randomised, double-blind, parallel group, placebo-controlled, multicentre phase three study to assess the efficacy and safety of Olaparib versus placebo as adjuvant treatment in patients with germline BRCA1/2 mutations and high risk HER2 negative primary breast cancer who have completed definitive local treatment and neoadjuvant or adjuvant chemotherapy [BIG 6- 13/NSABP B-55]

Dr Yoland Antill

Phase three study evaluating palbociclib (PD-0332991), a cyclin-dependent kinase (CDK) 4/6 inhibitor in patients with hormone- receptor positive, HER2-normal primary breast cancer with high relapse risk after neoadjuvant chemotherapy [GBG-78-BIG 1-13]

Dr Yoland Antill

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C A B R I N I H U M A N R E S E A RC H E T H I C S COM M IT T E E

56

RESEARCH AREA

PROJECT

PRINCIPAL RESEARCHER

ONCOLOGY AND HAEMATOLOGY CONTINUED

The timeline and quality of life implications of madarosis in patients undergoing cytotoxic chemotherapy for breast malignancy

Dr Yoland Antill

A phase 1b study to assess safety, tolerability and antitumor activity of the combination of BGB-3111 with obinutuzumab in subjects who have B-cell lymphoid malignancies

Professor Miles Prince

OPHTHALMOLOGY

RTA255-P001: Assessment of anatomical and functional outcomes in subjects treated with Ocriplasmin for Vitreomacular traction/symptomatic Vitreomacular adhesion (VMT/sVMA) [TDOC-0050303]

Associate Professor Wilson Heriot

PALLIATIVE CARE

Above and beyond: pastoral carers’ perspectives about using arts-based modalities in palliative care

Dr Clare O’Callaghan

Cabrini cardio-respiratory and palliative homecare shared initiative: description of patient cohort and resource utilisation

Dr Merlina Sulistio

Exploring the staff experience of death in an acute hospital

Dr Natasha Michael

A pharmacist-led intervention to improve administration of oral medications in patients that have oral medications modified

Robert Wojnar

Is adequate information provided for patients discharged with pain management from day procedure centre?

Jennifer Tan

Study of follistatin and activin activity in psoriasis

Dr Graeme Southwick

Study of topical delivery of Follistatin into skin

Dr Graeme Southwick

PSYCHO-ONCOLOGY

A pilot study of the mindful self-compassion program for people who have been diagnosed with cancer or haematological malignancy

Dr Joanne Brooker

QUALITY ASSURANCE

Domestic services review

Nazim Bayrak

Cellulitis in the hospital-in-the-home setting: do we follow the therapeutic guidelines (phase two)

Michelle Horsnell

REHABILITATION

Improving Cabrini health professionals’ capabilities to support self-management in a rehabilitation setting

Camilla Radia-George

RHEUMATOLOGY

A multicentre, randomised, double-blind, placebo-controlled, proof of concept study of ustekinumab in subjects who have active systemic lupus erythematosus [CNTO1275SLE2001]

Associate Professor Stephen Hall

Do bone marrow lesions identified by different MR imaging sequences have different clinical correlates in people with knee osteoarthritis?

Associate Professor Stephen Hall

Development of a core outcome measurement set for clinical trials in shoulder disorders

Professor Rachelle Buchbinder

PHARMACY

PLASTIC SURGERY

RESEARCH AREA

PROJECT

PRINCIPAL RESEARCHER

SURGERY

Placebo surgery for lumbar stenosis: perspectives of patients

Associate Professor Manuela Ferreira

Creation of a colorectal tissue micro array

Associate Professor Paul McMurrick

Does size matter? An Australian perspective of colorectal cancer and lymph nodes

Associate Professor Paul McMurrick

Prognostic significance of preoperative CEA value in node negative (stages one and two) colon cancer

Associate Professor Paul McMurrick

Relationship of patient factors, including comorbidities, to adverse outcome of wound breakdown and infection

Associate Professor Paul McMurrick

Contribution to international Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS) registry

Associate Professor Val Usatoff

Retrospective audit of IV fluid use in robotic urology and gynaecological surgeries at Cabrini

Dr Abhay Umranikar

Surgical outcome of duodenal adenoma and adenocarcinoma: the Alfred and Cabrini experience

Dr Angus Lee Chun Hin

Pathophysiology and treatment of non-alcoholic fatty liver disease: Effects of bariatric surgery

Dr Geraldine Ooi

A post-marketing, prospective, observational study following primary hip arthroplasty utilising the Apex Global Modular Hip Stem and the Global Acetabular Cup

Dr Neil Bergman

Examining the inflammatory profile of adipose tissue in oesophageal cancer

Mr Paul Burton

Outcomes of major bariatric surgical procedures

Mr Paul Burton

The accuracy of MRI staging T2 and T3 rectal cancer; the need for a standardised MRI reporting system

Mr Pravin Ranchod

ADIPOSe: Australasian decrease in intra-pelvic obesity for surgery trial – using VLEDs to reduce weight and improve outcomes in obese patients undertaking laparoscopic rectal cancer surgery

Mr Stephen Bell

Using apps for the management of surgeons’ preference card

Caz Derby

Australian Breast Device Registry (ABDR)

Gillian Farrell

Mini-sling or retropubic sling in women who have intrinsic sphincter deficiency – a RCT study (Mini RISD)

Dr Anna Rosamilia

UROGYNAECOLOGY

57

Publications

>

MONASH DEPARTMENT OF CLINICAL EPIDEMIOLOGY AT CABRINI HOSPITAL Publications Batterham RW, Hawkins M, Collin PA, Buchbinder R and Osborne R. (2016) Health Literacy: Applying current concepts to improve health services and reduce health inequalities. Public Health 132:3-12.

Beauchamp A, Buchbinder R, Dodson S, Batterham R, Elsworth GR, McPhee C, Sparkes L, Hawkins M and Osborne RH. (2015) Distribution of health literacy strengths and weaknesses across socio-demographic groups: a cross-sectional survey using the Health Literacy Questionnaire Health Literacy Questionnaire (HLQ).

BMC Public Health 15:678.

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Buchbinder R, Maher C and Harris I. (2015) Setting the research agenda for improving healthcare for musculoskeletal disorders. Nat Rev Rheumatol 1(10):597-605.

Buchbinder R, van Doornum S, Staples M, Lassere M and March L. (2015) Malignancy risk in Australian rheumatoid arthritis patients treated with anti-tumour necrosis factor therapy: a cohort study from the Australian Rheumatology Association Database. BMC Musculoskel Dis 16:309.

Busija L, Buchbinder R and Osborne RO. (2016) Development and preliminary evaluation of the OsteoArthritis Questionnaire (OA-Quest): A psychometric study. Osteoarthritis Cartilage doi:10.1016/j.joca.2016.03.014.

Clerehan R, Guillemin F and Buchbinder R. (2016) Using the evaluative linguistic framework for questionnaires to assess comprehensibility of self-report health questionnaires.

Value Health 19(4):335-42.

Dickensen E, Wall PDH, Robinson B, Fernandez M, Parsons H, Buchbinder R and Griffin DR. (2016) Prevalence of cam hip shape morphology: A systematic review.

Osteoarthritis Cartilage 24(6):949-61.

Egerton T, Diamond L, Buchbinder R, Bennell K and Slade SC. (2016) Barriers and enablers in primary care clinicians’ management of osteoarthritis: protocol for a systematic review and qualitative evidence synthesis.

BMJ Open 6(5):e011618.

French SD, Green SE, Francis JJ, Buchbinder R, O’Connor DA, Grimshaw JM and Michie S. (2015) Evaluation of the fidelity of an interactive face-to-face educational intervention to improve general practitioner management of back pain. BMJ Open 5(7):e007886.

Froud R, Bjørkli T, Bright P, Rajendran D, Buchbinder R, Underwood M, Evans D and Eldridge S. (2015) The effect of journal impact factor, reporting conflicts, and reporting funding sources, on standardised effect sizes in back pain trials: a systematic review and meta-regression. BMC Musculoskelet Disord 16:370.

GBD 2013 DALYs and HALE Collaborators. (2015) Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990–2013: quantifying the epidemiological transition. Lancet 386(10009):2145-91.

Global Burden of Disease Study 2013 Collaborators. (2015) Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet 386 (9995):743-800.

Kroon F, van der Burg L, Ramiro S, Landewé RB, Buchbinder R and van der Heijde. (2015) Non-steroidal anti-inflammatory drugs (NSAIDs) for axial spondyloarthritis (ankylosing spondylitis and non-radiographic axial spondyloarthritis). Cochrane Database of Systematic Reviews 7: CD010952.

Levinson M, Mills A, Oldroyd J, Gellie A, Barrett J, Staples M and Stephenson G. (2016) The impact of intensive care in a private hospital on patients aged 80 and over: health-related quality of life, functional status and burden versus benefit. Intern Med J 46(6): 694-702.

Page MJ, Green S, McBain B, Surace SJ, Deitch J, Lyttle N, Mrocki MA and Buchbinder R. (2016) Manual therapy and exercise for rotator cuff disease. Cochrane Database of Systematic Reviews 6: CD012224.

Page MJ, Green S, Mrocki MA, Surace SJ, Deitch J, McBain B, Lyttle N and Buchbinder R. (2016) Electrotherapy modalities for rotator cuff disease. Cochrane Database of Systematic Reviews 6: CD012225.

Page MJ, McKenzie JE, Green SE, Beaton DE, Jain NB, Lenza M, Verhagen AP, Surace S, Deitch J and Buchbinder, R. (2015) Core domain and outcome measurement sets for shoulder pain trials are needed: systematic review of physical therapy trials. J Clin Epidemiol 68(11):1270-81.

Petkovic J, Epstein J, Buchbinder R, Welch V, Rader T, Lyddiatt A, Clerehan R, Christensen R, Boonen A, Goel N, Maxwell L, Toupin-April K, De Wit M, Barton J, Flurey C, Jull J, Barnabe C, Pohl C, Duruöz T, Singh JA, Tugwell P and Guillemin F. (2015) Toward ensuring health equity: Readability and cultural equivalence of OMERACT patient-reported outcome measures. J Rheumatol 42(12): 2448-59.

Singh J, Dohm M, Sprowson A, Wall P, Richards B, Gossec L, Hawker G and Buchbinder R. (2015) Outcome domains and measures in total joint replacement clinical trials: Can we harmonise them? An OMERACT Collaborative Initiative. J Rheumatol 42(12): 2496-502.

Slade S, Dionne C, Underwood M, Buchbinder R et al. (2016) Consensus on Exercise Reporting Template (CERT): Modified Delphi study. Phys Ther DOI: 10.2522/ptj.20150668.

Slade SC, Kent P, Patel S, Bucknall T and Buchbinder R. (2015) Barriers to primary care clinician adherence to clinical guidelines for the management of low back pain: a systematic review and meta-synthesis of qualitative studies. Clin J Pain DOI:10.1097/AJP.0000000000000324.

Soon J, Buchbinder R, Close J, Hill C and Allan S. (2016) Identifying low value care - The Royal Australasian College of Physicians’ EVOLVE initiative. Med J Aust 204(5): 180-1.

Staples MP, Howe BM, Ringler M, Mitchell P, Wriedt C, Wark J, Ebeling P, Osborne R, Kallmes D and Buchbinder R. (2015) New vertebral fractures after vertebroplasty: 2-year results from a randomised controlled trial. Arch Osteoporosis 10: 229.

Stevens ML, Lin CW, Hancock MJ, Latimer J, Buchbinder R, Grotle M, van Tulder M, New CH, Wisby-Roth T and Maher CG. (2016) TOPS: Trial Of Prevention Strategies for low back pain in patients recently recovered from low back pain.

Study rationale and protocol BMJ Open 6(5): e011492.

Thoomes-de Graaf M, Scholten-Peeters GGM, Schellingerhout JM, Bourne AM, Buchbinder R, Koehorst M, Terwee CB and Verhagen AP. (2016) Evaluation of measurement properties of self-administered PROMS aimed at patients with non-specific shoulder pain and “activity limitations”: a systematic review. Qual Life Res 2016 DOI 10.1007/s11136-016-1277-7.

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Walker KJ, Dunlop W, Liew D, Staples MP, Johnson M, Ben-Meir M, Rodda HG, Turner I and Phillips, D. (2016) An economic evaluation of the costs of training a medical scribe to work in Emergency Medicine. Emerg Med J. 2016; doi: 10.1136/emermed-2016-205934.

Weller C, Buchbinder R and Johnston RV. (2016) Interventions for helping people adhere to compression treatments for venous leg ulceration. Cochrane Database of Systematic Reviews 3: CD008378.

Wilkins S, Haydon A, Porter I, Oliva K, Staples M, Carne P, McMurrick P and Bell S. (2016) Complete Pathological Response After Neoadjuvant Long-Course Chemoradiotherapy for Rectal Cancer and Its Relationship to the Degree of T3 Mesorectal Invasion. Dis Colon Rectum 59(5): 361-368.

Letters to the editor Buchbinder R, Maher C and Macpherson A. (2015) Letter to the editor in response to Lam J, et al. Australian clinical trial activity and burden of disease: an analysis of registered trials in National Health Priority Areas, Med J Aust 203 (2): 97-101.

Harris I and Buchbinder R. (2015) Letter to the editor in response to Duckett SJ, et al. Identifying and acting on potentially inappropriate care, Med J Aust 203 (4): 183.

Farrell M, Buchbinder R and Hall W. (2015) Response to Letters to the Editor for Should doctors prescribe cannabinoids? BMJ response to quick responses.

Reports Buchbinder R and Bourne A. What consumer information about knee arthroscopy is available in Australia: A review of patient leaflets provided by doctors, information easily accessible via the Internet and decision aids. For the Australian Commission Quality and Safety in Health Care, 17 July 2015.

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Conference abstracts Brennan-Olsen SL, Page RS, Lane SE, Lorimer M, Buchbinder R, Osborne RH, Pasco JA, Wluka AE, Sanders KM, Ebeling PE and Graves SE. Do geographic and socioeconomic variations exist in shoulder joint replacements? Australian Association of Gerontology 48th Annual National Conference “Place, Spirit, Heart: Exploring Experiences of Ageing”, Alice Springs, Nov 2015.

Buchbinder R and Macpherson A. Quality and Content of Consumer Information about Knee Arthroscopy in Australia.

Victorian ARA Annual Scientific Meeting, Aug 2015.

Richards BR, Buchbinder R, Lassere M and March L. Prevalence of pain, its impact and management in a population-based cohort of patients with rheumatoid arthritis: data from the Australian Rheumatology Association Database (ARAD). 2015 ACR/ARHP Annual Meeting, San Francisco, Nov 2015.

Slade SC, Kent P, Patel S, Bucknall T and Buchbinder R. Barriers to healthcare professional adherence to clinical guidelines for the management of low back pain: a systematic review and meta-synthesis of qualitative studies. 2015 ACR/ ARHP Annual Meeting, San Francisco, Nov 2015.

Published conference proceedings

Delir Haghighi P, Kang YB, Huynh T, Buchbinder R, Burstein F and Whittle S. Investigation of Environmental Associations of Fibromyalgia Pain Using Twitter Content Analysis. Cabrini Research Day, Oct 2015.

Staples M, Howe BM, Ringler M, Mitchell P, Wriedt C, Wark J, Ebeling P, Osborne R, Kallmes D and Buchbinder R. New vertebral fractures after vertebroplasty: Two-year results from a randomised, placebo-controlled trial. Cabrini Research Day, Oct, 2015.

Goh TY, Haghighi Pari D, Burstein F and Buchbinder R. Developing a contextual model towards understanding low back pain. 19th Pacific Asia Conference on Information Systems (PACIS 2015), Singapore, July 2015. Paper 64 http:// aisel.aisnet.org/pacis2015/64.

Delir Haghighi P, Kang YB, Huynh T, Buchbinder R, Burstein F and Whittle S. Investigation of Environmental Associations of Fibromyalgia Pain Using Twitter Content Analysis. 2015 ACR/ARHP Annual Meeting, San Francisco, Nov 2015.

Staples M, Howe BM, Ringler M, Mitchell P, Wriedt C, Wark J, Ebeling P, Osborne R, Kallmes D and Buchbinder R. New vertebral fractures after vertebroplasty: Two-year results from a randomised, placebo-controlled trial. 2015 ACR/ARHP Annual Meeting, San Francisco, Nov 2015.

Slade SC, Dionne C, Underwood M and Buchbinder R. Standardised method for reporting exercise programs: a modified Delphi study Physiotherapy 2015; 101(Supplement 1): S1238–eS1642

Dodson S, Mech P, Batterham R, Beauchamp A, Buchbinder R and Osborne RH. Development and application of the Health Literacy Response Framework.

European Health Literacy Conference, Brussels, Nov 2015.

Slade SC, Kent P, Patel S, Bucknall T and Buchbinder R. Barriers to healthcare professional adherence to clinical guidelines for the management of low back pain: a systematic review and meta-synthesis of qualitative studies. Low Back Pain Forum, Buxton, UK, May 2016.

Slade SC, Kent PK, Patel S, Bucknall T and Buchbinder R. Barriers to primary care clinician adherence to clinical guidelines for the management of low back pain: a systematic review and meta-synthesis of qualitative studies.

Physiotherapy 2015; 101(Supplement 1): S1238–eS1642.

Hawkins M, Beauchamp A, Batterham R, Dodson S, McPhee C, Buchbinder R and Osborne RH. Improving equity and chronic disease outcomes by optimising organisational responsiveness to consumer health literacy needs: The Ophelia Victoria project. PHAA conference, Hobart, Sept 2015.

Slade SC, Patel S, Underwood M and Keating JL. What are patient beliefs and perceptions about exercise for non-specific chronic low back pain: a systematic review of qualitative research? Physiotherapy 2015; 101(Supplement 1): eS1238–eS1642.

CABRINI MONASH DEPARTMENT OF MEDICAL ONCOLOGY THE SZALMUK FAMILY DEPARTMENT OF MEDICAL ONCOLOGY Publications

Page M, Green S, McBain B, Surace S, Deitch J, Lyttle N, Mrocki M and Buchbinder R. Manual therapy and exercise for rotator cuff disease: a Cochrane review. Annual European Congress of Rheumatology EULAR, London UK, June 2016.

Antill YC, Dowty JG, Win AK, Thompson T, Walsh MD, Cummings MC, Gallinger S, Lindor NM, Le Marchand L, Hopper JL, Newcomb PA, Haile RW, Church J, Tucker KM, Buchanan DD, Young JP, Winship IM and Jenkins MA. (2015) Lynch syndrome and cervical cancer. Int J Cancer 137(11): 2757-61.

Askmyr M, White KE, Jovic T, King HA, Quach JM, Maluenda AC, Baker EK, Smeets MF, Walkley CR and Purton LE. (2015) Ciliary neurotrophic factor has intrinsic and extrinsic roles in regulating B cell differentiation and bone structure. Sci Rep 5: 15529.

Bhattacharya S, Chalk AM, Ng AJ, Martin TJ, Zannettino AC, Purton LE, Lu J, Baker EK and Walkley CR. (2016) Increased miR-155-5p and reduced miR-148a-3p contribute to the suppression of osteosarcoma cell death. Oncogene doi: 10.1038/onc.2016.68.

Blombery P, Thompson E, Jones K, Mir Arnau G, Lade S, Markham JF, Li J, Deva A, Johnstone RW, Khot A, Prince HM and Westerman D. (2016) Whole exome sequencing reveals activating JAK1 and STAT3 mutations in breast-implant associated anaplastic large cell lymphoma. Haematologica pii: haematol.2016.146118.

Chan KL, Lokan J, Tam CS, Lew TE and Prince HM. (2016) Central nervous system immune reconstitution inflammatory syndrome after ibrutinib therapy for Richter transformation.

Leuk Lymphoma 21: 1-4.

Dumond JB, Francis O, Cottrell M, Trezza C, Prince HM, Mollan K, Sykes C, Torrice C, White N, Malone S, Wang R, Van Dam C, Patterson KB, Hudgens MG, Sharpless NE and Forrest A. (2016) Tenofovir/emtricitabine metabolites and endogenous nucleotide exposures are associated with p16INK4a expression in subjects on combination therapy.

Antivir Ther doi: 10.3851/IMP3017.

Ferraro D, Goldstein D, O’Connell RL, Zalcberg JR, Sjoquist KM, Tebbutt NC, Grimison P, McLachlan S, Lipton L, Vasey P, Gebski VJ, Aiken C, Cronk M, Ng S, Karapetis CS and Shannon J; behalf of the Australasian Gastro-Intestinal Trials Group. (2016) TACTIC: a multicentre, open-label, single-arm phase II trial of panitumumab, cisplatin, and gemcitabine in biliary tract cancer. Cancer Chemother Pharmacol DOI:10.1007/s00280-016-3089-4.

Foss F, Horwitz S, Pro B, Prince HM, Sokol L, Balser B, Wolfson J and Coiffier B. (2016) Romidepsin for the treatment of relapsed/refractory peripheral T cell lymphoma: prolonged stable disease provides clinical benefits for patients in the pivotal trial. J Hematol Oncol 9:22. doi: 10.1186/s13045-016-0243-8.

Gibbs P, Do C, Lipton L, Cade DN, Tapner MJ, Price D, Bower GD, Dowling R, Lichtenstein M and van Hazel GA. (2015) Phase II trial of selective internal radiation therapy and systemic chemotherapy for liver-predominant metastases from pancreatic adenocarcinoma. BMC Cancer 15: 802.

Gupte A, Baker EK, Wan SS, Stewart E, Loh A, Shelat AA, Gould CM, Chalk AM, Taylor S, Lackovic K, Karlström Å, Mutsaers AJ, Desai J, Madhamshettiwar PB, Zannettino AC, Burns C, Huang DC, Dyer MA, Simpson KJ and Walkley CR. (2015) Systematic Screening Identifies Dual PI3K and mTOR Inhibition as a Conserved Therapeutic Vulnerability in Osteosarcoma. Clin Cancer Res 21(14): 3216-29.

Haines IE. (2015) Negotiating the complex maze of claims of dietary cures for cancer. Med J Aust. 203(4): 196-7e.1.

Haines IE, Ablin RJ and Miklos GL. (2016) Screening for prostate cancer: time to put all the data on the table.

BMJ 353: i2574.

Harrison SJ, Quach H, Spencer A and Prince HM. (2015) Comment on “Retrospective matched-pairs analysis of bortezomib plus dexamethasone versus bortezomib monotherapy in relapsed multiple myeloma”. Haematologica 100(9): e379.

Hersh EM, Del Vecchio M, Brown MP, Kefford R, Loquai C, Testori A, Bhatia S, Gutzmer R, Conry R, Haydon A, Robert C, Ernst S, Homsi J, Grob JJ, Kendra K, Agarwala SS, Li M, Clawson A, Brachmann C, Karnoub M, Elias I, Renschler MF and Hauschild A. (2015) A randomised, controlled phase III trial of nab-Paclitaxel versus dacarbazine in chemotherapy-naïve patients with metastatic melanoma.

Ann Oncol 26(11): 2267-74.

Hu H, Johani K, Almatroudi A, Vickery K, Van Natta B, Kadin ME, Brody G, Clemens M, Cheah CY, Lade S, Joshi PA, Prince HM and Deva AK. (2016) Bacterial Biofilm Infection Detected in Breast Implant-Associated Anaplastic Large-Cell Lymphoma. Plast Reconstr Surg 137(6): 1659-69.

Jefford M, Gough K, Drosdowsky A, Russell L, Aranda S, Butow P, Phipps-Nelson J, Young J, Krishnasamy M, Ugalde A, King D, Strickland A, Franco M, Blum R, Johnson C, Ganju V, Shapiro J, Chong G, Charlton J, Haydon A and Schofield P. (2016) A randomised controlled trial of a nurse-led supportive care package (SurvivorCare) for survivors of colorectal cancer. Oncologist DOI:10.1634/ theoncologist.2015-0533.

Jorissen RN, Christie M, Mouradov D, Sakthianandeswaren A, Li S, Love C, Xu ZZ, Molloy PL, Jones IT, McLaughlin S, Ward RL, Hawkins NJ, Ruszkiewicz AR, Moore J, Burgess AW, Busam D, Zhao Q, Strausberg RL, Lipton L, Desai J, Gibbs P and Sieber OM. (2015) Wild-type APC predicts poor prognosis in microsatellite-stable proximal colon cancer. Br J Cancer 113(6): 979-88.

Kenealy M, Patton N, Filshie R, Nicol A, Ho SJ, Hertzberg M, Mills T, Prosser I, Link E, Cowan L, Zannino D and Seymour JF. (2016) Results of a phase II study of thalidomide and azacitidine in patients with clinically advanced myelodysplastic syndromes (MDS), chronic myelomonocytic leukemia (CMML) and low blast count acute myeloid leukaemia (AML). Leuk Lymphoma 7: 1-10.

Lawrence MG, Pook DW, Wang H, Porter LH, Frydenberg M, Kourambas J, Appu S, Poole C, Beardsley EK, Ryan A, Norden S, Papargiris MM, Risbridger GP and Taylor RA. (2015) Establishment of primary patient-derived xenografts of palliative TURP specimens to study castrate-resistant prostate cancer. Prostate 75(13): 1475-83.

Lew TE, Cheah CY, Carney DA, Prince HM, Wolf M, Bazargan A, Januszewicz EH, Filshie R, Westerman D, Seymour JF and Tam CS. (2016) Dose-reduced fludarabine, cyclophosphamide and rituximab is well tolerated in older patients with chronic lymphocytic leukaemia and has preserved therapeutic efficacy. Leuk Lymphoma 57(5): 1044-53.

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Lipton A, Fizazi K, Stopeck AT, Henry DH, Smith MR, Shore N, Martin M, Vadhan-Raj S, Brown JE, Richardson GE, Saad F, Yardley DA, Zhou K, Balakumaran A and Braun A. (2016) Effect of denosumab versus zoledronic acid in preventing skeletal-related events in patients with bone metastases by baseline characteristics. Eur J Cancer 53: 75-83.

Luen S, Wong SW, Mar V, Kelly JW, McLean C, McArthur GA and Haydon A. (2015) Primary tumor thickness is a prognostic factor in stage IV melanoma: a retrospective study of primary tumor characteristics. Am J Clin Oncol DOI:10.1097/COC.0000000000000226.

Malouf P, Gibbs P, Shapiro J, Sockler J and Bell S. (2016) Australian contemporary management of synchronous metastatic colorectal cancer. ANZ J Surg doi: 10.1111/ans.13619.

62

Meani RE, Pan Y, McLean C, Haydon A, Leung M and Kelly JW. (2015) The Victorian Melanoma Service: A 20-year review of an Australian multidisciplinary cancer service.

Australas J Dermatol doi: 10.1111/ajd.12413.

Meiser B, Quinn VF, Gleeson M, Kirk J, Tucker KM, Rahman B, Saunders C, Watts KJ, Peate M, Geelhoed E, Barlow-Stewart K, Field M, Harris M, Antill YC and Mitchell G. (2016) When knowledge of a heritable gene mutation comes out of the blue: treatment-focused genetic testing in women newly diagnosed with breast cancer. Eur J Hum Genet doi: 10.1038/ejhg.2016.69.

Oberoi DV, White V, Jefford M, Giles GG, Bolton D, Davis I, Winship I, Prince HM, Millar J, Harrison S, Kay A and Hill D. (2016) Caregivers’ information needs and their ‘experiences of care’ during treatment are associated with elevated anxiety and depression: a cross-sectional study of the caregivers of renal cancer survivors. Support Care Cancer DOI:10.1007/ s00520-016-3245-8.

Parakh S, Wong HL, Rai R, Ali S, Field K, Shapiro J, Wong R, Nott L, Gibbs P and Yip D. (2015) Patterns of care and outcomes for elderly patients with metastatic colorectal cancer in Australia. J Geriatr Oncol 6(5): 387-94.

Parisot JP, Thorne H, Fellowes A, Doig K, Lucas M, McNeil JJ, Doble B, Dobrovic A, John T, James PA, Lipton L, Ashley D, Hayes T, McMurrick P, Richardson G, Lorgelly P, Fox SB and Thomas DM. (2015) “Cancer 2015”: A Prospective, Population-Based Cancer Cohort-Phase 1: Feasibility of Genomics-Guided Precision Medicine in the Clinic. J Pers Med 5(4): 354-69.

Pavlakis N, Sjoquist KM, Martin AJ, Tsobanis E, Yip S, Kang YK, Bang YJ, Alcindor T, O’Callaghan CJ, Burnell MJ, Tebbutt NC, Rha SY, Lee J, Cho JY, Lipton L, Wong M, Strickland A, Kim JW, Zalcberg JR, Simes J and Goldstein D. (2016) Regorafenib for the treatment of advanced gastric cancer (INTEGRATE): a multinational placebo-controlled phase II trial. J Clin Oncol DOI:10.1200/JCO.2015.65.1901.

Prince HM. (2015) CD30 As a target for the treatment of cutaneous T-Cell lymphoma. J Clin Oncol 33(32): 3691-6.

Scarisbrick JJ, Prince HM, Vermeer MH, Quaglino P, Horwitz S, Porcu P, Stadler R, Wood GS, Beylot-Barry M, Pham-Ledard A, Foss F, Girardi M, Bagot M, Michel L, Battistella M, Guitart J, Kuzel TM, Martinez-Escala ME, Estrach T, Papadavid E, Antoniou C, Rigopoulos D, Nikolaou V, Sugaya M, Miyagaki T, Gniadecki R, Sanches JA, Cury-Martins J, Miyashiro D, Servitje O, Muniesa C, Berti E, Onida F, Corti L, Hodak E, Amitay-Laish I, Ortiz-Romero PL, Rodríguez-Peralto JL, Knobler R, Porkert S, Bauer W, Pimpinelli N, Grandi V, Cowan R, Rook A, Kim E, Pileri A, Patrizi A, Pujol RM, Wong H, Tyler K, Stranzenbach R, Querfeld C, Fava P, Maule M, Willemze R, Evison F, Morris S, Twigger R, Talpur R, Kim J, Ognibene G, Li S, Tavallaee M, Hoppe RT, Duvic M, Whittaker SJ and Kim YH. (2015) Cutaneous Lymphoma International Consortium Study of Outcome in Advanced Stages of Mycosis Fungoides and Sézary Syndrome: Effect of Specific Prognostic Markers on Survival and Development of a Prognostic Model.

J Clin Oncol 33(32): 3766-73.

Schenberg T, Mitchell G, Taylor D and Saunders C. (2015) MRI screening for breast cancer in women at high risk; is the Australian breast MRI screening access program addressing the needs of women at high risk of breast cancer? J Med Radiat Sci 62(3): 212-25.

Segelov E, Waring P, Desai J, Wilson K, Gebski V, Thavaneswaran S, Elez E, Underhill C, Pavlakis N, Chantrill L, Nott L, Jefford M, Khasraw M, Day F, Wasan H, Ciardiello F, Karapetis C, Joubert W, van Hazel G, Haydon A, Price T, Tejpar S, Tebbutt N and Shapiro J. (2016) ICECREAM: randomised phase II study of cetuximab alone or in combination with irinotecan in patients with metastatic colorectal cancer with either KRAS, NRAS, BRAF and PI3KCA wild type, or G13D mutated tumours.

BMC Cancer 16(1): 339.

Thomas DM, Fox S, Lorgelly PK, Ashley D, Richardson G, Lipton L, Parisot JP, Lucas M, McNeil J and Wright M; Cancer 2015 Investigators. (2015) Cancer 2015: a longitudinal whole-of-system study of genomic cancer medicine. Drug Discov Today 20(12): 1429-32.

Toleman MS, Herbert K, McCarthy N and Church DN. (2016) Vaccination of chemotherapy patients-effect of guideline implementation. Support Care Cancer. 24(5): 2317-21.

Whittaker S, Hoppe R and Prince HM. (2016) How I treat mycosis fungoides and Sézary syndrome. Blood 127(25): 3142-53.

Wilkins S, Haydon A, Porter I, Oliva K, Staples M, Carne P, McMurrick P and Bell S. (2016) Complete Pathological Response After Neoadjuvant Long-Course Chemoradiotherapy for Rectal Cancer and Its Relationship to the Degree of T3 Mesorectal Invasion. Dis Colon Rectum 59(5): 361-8.

Wong A, Fullerton S, Spruyt O, Brady B, McArthur G and Sandhu S. (2016) Integration of Immuno-Oncology and Palliative Care. J Clin Oncol 34(13): 1561-2.

Wong HL, Lee B, Field K, Lomax A, Tacey M, Shapiro J, McKendrick J, Zimet A, Yip D, Nott L, Jennens R, Richardson G, Tie J, Kosmider S, Parente P, Lim L, Cooray P, Tran B, Desai J, Wong R and Gibbs P. (2016) Impact of primary tumor site on bevacizumab efficacy in metastatic colorectal cancer. Clin Colorectal Cancer 15(2): e9-e15.

Wong SF, Wong HL, Field KM, Kosmider S, Tie J, Wong R, Tacey M, Shapiro J, Nott L, Richardson G, Cooray P, Jones I, Croxford M and Gibbs P. (2015) Primary tumor resection and overall survival in patients with metastatic colorectal cancer treated with palliative intent. Clin Colorectal Cancer doi: 10.1016/j.clcc.2015.12.010.

Wong Doo N, Makalic E, Joo JE, Vajdic CM, Schmidt DF, Wong EM, Jung CH, Severi G, Park DJ, Chung J, Baglietto L, Prince HM, Seymour JF, Tam C, Hopper JL, English DR, Milne RL, Harrison SJ, Southey MC and Giles GG. (2016) Global measures of peripheral blood-derived DNA methylation as a risk factor in the development of mature B-cell neoplasms. Epigenomics 8(1): 55-66.

Woodward N, White M, Pugliano L, Tsoi D and Ryan C. (2016) Management of patients treated with pertuzumab in the Australian clinical practice setting. Asia Pac J Clin Oncol Suppl 2: 5-15.

CABRINI MONASH UNIVERSITY DEPARTMENT OF MEDICINE Publications Levinson M, Ho S, Mills A, Kelly B, Gellie A and Rouse A. (2016) Language and understanding of cardiopulmonary resuscitation amongst an aged inpatient population. Psychol Health Med doi:10.1080/13548506.2016.1147053.

Levinson M, Mills A, Oldroyd J, Gellie A, Barrett J, Staples M and Stephenson G. (2016) The impact of intensive care in a private hospital on patients aged 80 and over: health related quality of life, functional status and burden versus benefit.

Intern Med J doi:10.1111/imj.13079.

Conference abstracts Levinson M. Why didn’t you write an NFR? Australian Association of Gerontology Conference, Ayers Rock, November 2015.

Levinson M. The incidence and diagnosis of delirium in ≥ 80-year-old intensive care patients. Canadian Critical Care Conference, Whistler, March 2016.

Mills A. Doctors’ attitudes towards Not for Resuscitation Orders. 5th International Society of Advance Care Planning and End of Life Care Conference, Munich, September 2015.

Mills A. Advance care plans and Not for Resuscitation orders: a multi-site audit and review across five Australian hospitals.

5th International Society of Advance Care Planning and End of Life Care Conference, Munich, September 2015.

CENTRE FOR ALLIED HEALTH RESEARCH AND EDUCATION Publications Brusco NK and Watts JJ. (2015) Empirical evidence of recall bias for primary healthcare visits. BMC Health Services Research 15: 381.

Darzins SW, Imms C, Di Stefano M and Radia-George CA. (2016) Personal Care Participation Assessment and Resource Tool: Clinical utility for inpatient rehabilitation: Utilité clinique du Personal Care Participation Assessment and Resource Tool pour la réadaptation en milieu hospitalier. Canadian Journal of Occupational Therapy doi:10.1177/0008417416648446.

Hay-Smith E, McClurg D, Frawley H and Dean S. (2016) Exercise adherence: integrating theory, evidence and behaviour change techniques. Physiotherapy 102(1): 7-9.

Higgins RO, Rogerson M, Murphy BM, Navaratnam H, Butler MV, Barker L, Turner A, Lefkovits J and Jackson AC. (2015) Cardiac rehabilitation online pilot: extending reach of cardiac rehabilitation. The Journal of cardiovascular nursing DOI 10.1097/JCN.0000000000000297.

Jackson AC, Liang RPT, Frydenberg E, Higgins RO and Murphy BM. (2016) Parent education programmes for special healthcare needs children: a systematic review. Journal of Clinical Nursing 25(11-12):1528-47.

Jobling K, Lau P, Kerr D, Higgins RO, Worcester MU, Angus L, Jackson AC and Murphy BM. (2015) Bundap Marram Durn Durn: Engagement with Aboriginal women experiencing comorbid chronic physical and mental health conditions Australian and New Zealand Journal of Public Health Suppl 1: S30-5

Lin K, Frawley H, Denehy L, Feil D and Granger C. (2016) Exercise interventions for patients with gynaecological cancer: a systematic review and meta-analysis. Physiotherapy doi:10.1016/j.physio.2016.02.006.

Murphy BM, Higgins RO, Jackson AC, Edington J, Jackson A and Worcester MU. (2015) Patients want to know about the ‘cardiac blues’. Australian family physician, 44: 826-832.

Murphy BM, Higgins RO, Shand L, Page K, Holloway E, Le Grande MR and Jackson AC. (2016) Improving health professionals’ self-efficacy to support cardiac patients’ emotional recovery: the ‘Cardiac Blues Project’. European Journal of Cardiovascular Nursing 10.1177/1474515116643869.

Book chapters Murphy BM, Higgins RO, Jackson AC, Byrne D and Alvarenga M. (2016) ‘Anxiety, Depression, and Psychological Adjustment After an Acute Cardiac Event’ in Alvarenga, ME and Byrne D. (eds), Handbook of Psychocardiology, pp. 511524, Springer, Heidelberg.

Conference abstracts Bilney B, Mcginley J, Danoudis M, Morris M and Higgins R. Physical activity and exercise information for people with Parkinson’s disease: Expressed preference for source and format. Australian Physiotherapy Association Conference, Queensland, Australia, October 2015.

Brusco NK. Are weekend rehabilitation services value for money? An economic evaluation alongside a randomised controlled trial. 11th World Congress in Health Economics, Milan, Italy, July 2015.

Brusco NK. Are weekend allied health rehabilitation services value for money? An economic evaluation alongside a randomised, controlled trial. Health Service Research Association of Australia and New Zealand 9th Health Service and Policy Research Conference, Melbourne, Australia, December 2015.

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Daly E, Todorovic L, Mcleod J, Barker L, Anthonisz B, Higgins R and Freilich R. Integrated disease management for neuro-oncology patients and their families: Putting patient centred care into practice. International Society for NeuroOncology Annual Scientific Meeting, San Antonio, USA, November 2015.

Davidson MJ, Bryant AL and Frawley HC. Correlation between muscle stiffness and pain in women with vulvodynia.

Australian Physiotherapy Association Conference, Queensland, Australia, October 2015.

Frawley HC. Does pelvic floor muscle training help female sexual function? Australian Physiotherapy Association Conference, Queensland, Australia, October 2015.

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Frawley HC. Implementation of research into practice: tips, tricks and a case study. Victorian Continence Resource Centre Seminar “The Many Faces of Research: Education day for continence professionals”, Melbourne, Australia, February 2016.

Frawley HC. Chronic Pelvic Pain – Physiotherapy Management. Pelvic Floor Clinic, Oslo, Norway, April 2016.

Frawley HC. Continence and Women’s Health Physiotherapy: Clinical Practice, Education and Research in Australia. Pelvic, Obstetric, Gynaecologic Scottish Branch Annual Meeting, Glasgow, Scotland, April 2016.

Frawley HC. A multidisciplinary rehabilitation program for patients following surgery for abdomino-pelvic cancer.

Pelvic, Obstetric, Gynaecologic Scottish Branch Annual Meeting, Glasgow, Scotland, April 2016.

Frawley HC. Pelvic Floor Muscle Pain and Tone – how do we measure them? Pelvic, Obstetric, Gynaecologic Scottish Branch Annual Meeting, Glasgow, Scotland, April 2016.

Frawley HC, Lin KY, Granger C, Denehy L, Higgins R, Butler M and Lees-Trinca I. A multidisciplinary rehabilitation program for patients following surgery for abdomino-pelvic cancer. Australian Physiotherapy Association Conference, Queensland, Australia, October 2015.

Frawley H, Lin KY, Granger C, Denehy L, Higgins R, Butler M and Lees-Trinca I. A multidisciplinary rehabilitation program for patients following surgery for abdomino-pelvic cancer.

Cabrini Research Day, Melbourne, Australia, October 2015.

Vonier C, Luxford C, Barker L and Higgins R. Aligning Chronic Disease Staff goal setting practices with best practice guidelines. Disease Management Association Annual National Conference. Melbourne, Australia, September 2015.

Higgins, R. Psychological impact of chronic disease: Normal adjustment or pathological? Chronic Disease and Mental Health Symposium, Sydney, Australia, February 2016.

Vonier C, Luxford C, Barker L and Higgins R. Aligning chronic disease staff goal-setting practices with best practice guidelines. Cabrini Research Day, Melbourne, Australia, October 2015.

Higgins R, Murphy B, Holloway E, Page K and Jackson A. ONTRACK after the cardiac blues: Translational research in action Disease Management Association Annual National Conference Melbourne, Australia, September 2015 Higgins RM, Navaratnam H and Jackson A. Teleheart: Piloting of telephone delivered cardiac rehabilitation.

Australian Cardiovascular Health and Rehabilitation Association Annual Scientific Conference. Melbourne, Australia, August 2015.

McCaskie D. Challenges of implementing a protocol-led dysphagia screening tool in stroke. Cabrini Research Day, Melbourne, Australia, October 2015.

Mcginley JL, Danoudis M, Bilney B, Morris M and Higgins R. Physical activity of Australians with Parkinson’s disease. Australian Physiotherapy Association Conference, Queensland, Australia, October 2015.

Morris M, Rocha J and McClelland J. Complementary therapies for Parkinson’s Disease. National Allied Health Conference, Melbourne, Australia, November 2015.

Morrison S. Multidisciplinary case panel discussion. Prostate Cancer World Congress, Cairns, Australia, August 2015.

Vonier Y and Ferrier, A. Laying the groundwork for great goal setting in rehabilitation. Cabrini Research Day, Melbourne, Australia, October 2015.

SZALMUK FAMILY PSYCHO-ONCOLOGY UNIT Publications Beasley E, Brooker, J, Warren N, Fletcher J, Boyle C, Ventura A and Burney S. (2015) The lived experience of volunteering in a palliative care biography service. Palliative and Supportive Care 13(5): 1417-1425.

Kearns N, Shawyer F, Brooker J, Graham A, Enticott J, Martin P and Meadows G. (2016) Does rumination mediate the relationship between mindfulness and depressive relapse? Psychology and Psychotherapy: Theory, Research and Practice 89(1): 33-49.

Michael N, O’Callaghan C, Brooker J, Walker H, Hiscock R and Phillips D. (2016) Introducing a model incorporating early integration of specialist palliative care: A qualitative research study of staff’s perspectives. Palliative Medicine 30: 303-12.

Morrison S. The role of the pelvic floor in sexual pain.

ASPOG (Australian Society of Psychosocial Obstetrics and Gynaecology) National conference. Melbourne, Australia, August 2015.

Robinson S, Kissane D, Brooker J, Hempton C, Michael N, Fischer J, Franco M, Sulistio M, Clarke D, Ozmen M and Burney S. (2016) Refinement and revalidation of the demoralization scale: DS-II–external validity.

Cancer 122(14): 2260-7.

Shand LK, Higgins RM, Murphy BM and Jackson AJ. The HRC Network – An online community for health professionals. Australian Cardiovascular Health and Rehabilitation Association Annual Scientific Conference.

Melbourne, Australia, August 2015.

Robinson S, Kissane D, Brooker J, Michael N, Fischer J, Franco M, Hempton C, Sulistio M, Pallant J, Clarke D and Burney S. (2016) Refinement and revalidation of the demoralization scale: the DS-II–internal validity. Cancer 122(14): 2251-9.

Robinson S, Kissane D, Brooker J and Burney S. (2016) A review of the construct of demoralisation: History, definitions, and future directions for palliative care. American Journal of Hospice and Palliative Care 33(1): 93-101.

Warren N, Melrose D, Brooker J and Burney S. (2016) Psychosocial distress in women diagnosed with gynecological cancer. Journal of Health Psychology doi: 10.1177/1359105316640061.

Hinz A. Innovation in Allocations. Victorian Perioperative Nurses Group Annual Conference, Melbourne, August 2015.

Johnson M, Miller J and Boyd L. Improving CPR performance using in-situ simulation. Simulation Users Network Conference, Gold Coast, May 2015.

Johnson M, Miller J and Boyd L. Improving CPR performance using in-situ simulation. 2016 Asia Pacific Healthcare Simulation, Kuala Lumpur, April 2016.

Published conference proceedings Juraskova I, Hyatt A, Frydenberg, M, O’Callaghan C, Brooker J, Murphy D, Wootten A, Burney S and Schofield P. (2015) ASTROID (Active Surveillance and other Treatment Options for Prostate Cancer): A decision aid. 2nd Prostate Cancer World Congress, Aug 17-21, 2015, Cairns, Australia.

British Journal of Urology International 116: 51-51.

Robinson S, Kissane D and Brooker J. (2016) Refinement and revalidation of the demoralization scale: The DS-II. 4th Annual Scientific Conference of the European Association for Psychosomatic Medicine, Jun 16-18, 2016, Luleå, Sweden.

Journal of Psychosomatic Research 85: 78.

CENTRE FOR NURSING RESEARCH Publications Lowe G, Plummer V and Boyd L. (2016) Perceptions of NP roles: nurse practitioners, managers and policy advisers. The Journal for Nurse Practitioners 12: 303-310.

Walker KJ, Dunlop W, Liew D, Staples MP, Johnson M, Ben-Meir M, Rodda HG, Turner I and Phillips D. (2016) An economic evaluation of the costs of training a medical scribe to work in Emergency Medicine. Emergency Medicine Journal doi: 10.1136/emermed-2016-205934.

Johnson M, Peat A, Warren T and Boyd L. Targeted simulation to improve patient safety and organisational learning. 2015 ASCSM Asia Pacific Annual, Melbourne, October 2015.

Morgan M, Pereira-Salgado A, Boyd L and Mader P. Meaningful conversations: a literature review examining cultural and religious considerations in online advance care planning tools. Advance Care Planning and End of Life conference, Melbourne, November 2015.

Morgan M, Pereira-Salgado A, Boyd L, Mader P, Walker H and Islam A. Developing an online resource for religious and cultural advance care planning – a literature review. Cabrini Research Day, October 2015.

Pereira-Salgado A and Boyd L. Process and impact evaluation of online resources for the National Safety and Quality Health Service Standards (NSQHSS). Joint Australasian College of Health Services Management/ Australian Council on Healthcare Standards Annual Congress, Melbourne, October 2015.

Pereira-Salgado A, Morgan M, Boyd L, Johnson M, Mader P and Walker H. An environmental scan for Australian-based advance care planning online resources: cultural and religious considerations. Cabrini Research Day, October 2015.

Seletto K, Lo C, Gomez Y, Wilke A and O’Reilly M. Antimicrobial Stewardship – A Nursing Perspective.

Antimicrobial Stewardship Pharmacist Seminar, Peter Doherty Institute, Melbourne, July 2015.

INTENSIVE CARE UNIT Publications Philpot SJ, Aranha S, Pilcher DV and Bailey M. (2016) Randomised, double blind, controlled trial of the provision of information about the benefits of organ donation during a family donation conversation. PLoS One 11(6):e0155778.

Book chapters Brewster D and Reeves J. (2015) ‘Interpreting haematology investigations’ in Symons J, Myles P, Mehra R and Ball C (eds), Perioperative medicine for the junior clinician, Wiley, USA. 65

Brewster D and Reeves J. (2015) ‘Interpreting biochemistry investigations’ in Symons J, Myles P, Mehra R and Ball C (eds), Perioperative medicine for the junior clinician, Wiley, USA. Brewster D and Reeves J. (2015) ‘Interpreting lung function tests’ in Symons J, Myles P, Mehra R and Ball C (eds), Perioperative medicine for the junior clinician, Wiley, USA. Brewster D and Reeves J. (2015) ‘Interpreting radiological investigations’ in Symons J, Myles P, Mehra R and Ball C (eds), Perioperative medicine for the junior clinician, Wiley, USA. Story D, Brewster D and Reeves J. (2015) Blood gas interpretation in Symons J, Myles P, Mehra R and Ball C (eds), Perioperative medicine for the junior clinician, Wiley, USA.

PALLIATIVE CARE RESEARCH UNIT Publications

Conference abstracts Clarke A. Perioperative Practitioner Pathway. Victorian Perioperative Nurses Group State Conference, Melbourne, July 2015.

Pereira-Salgado A, Morgan M, Boyd L and Mader P. Australian-based advance care planning online resources: What religious and cultural information would the consumer and health professional find? Advance Care Planning and End of Life conference, Melbourne, November 2015.

Michael N, O’Callaghan C and Clayton J. (2016) Exploring the utility of the vignette technique in promoting advance care planning discussions with cancer patients and caregivers. Patient Education and Counseling 99(8): 1406-12.

Michael N, O’Callaghan C, Brooker J, Walker H, Hiscock R and Phillips D. (2016) Introducing a model incorporating early integration of specialist palliative care: A qualitative research study of staff’s perspectives. Palliative Medicine 30:303-12.

O’Callaghan C, Schofield P, Butow P, Nolte L, Price M, Tsintziras S, Sze M, Thein T, Yiu D, Mireskandari S, Goldstein D and Jefford M. (2016) “I might not have cancer if you didn’t mention it”: A qualitative study on information needed by culturally diverse cancer survivors. Supportive Care in Cancer 24: 409-418.

Robinson S, Kissane DW, Brooker J, Hempton C, Michael N, Fischer J et al. (2016) Refinement and revalidation of the demoralisation scale: The DS-II-external validity.

Cancer 122(14): 2260-7.

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Robinson S, Kissane DW, Brooker J, Michael N, Fischer J, Franco M et al. (2016) Refinement and revalidation of the demoralisation scale: The DS-II-internal validity. Cancer 122(14): 2251-9.

Published conference proceedings Juraskova I, Hyatt A, Frydenberg M, O’Callaghan C, Brooker J, Murphy D, Wootten A, Burney S and Schofield P. (2015) ASTROID (Active Surveillance and other Treatment Options for Prostate Cancer): a decision aid. BJU International 116: 51-51.

Michael N. (2015) Getting the wrong end of the stick: Promoting a patient and family centred approach to advance care planning in cancer. BMC Supportive and Palliative Care 5(Suppl 2): A24-25.

O’Callaghan C. (2016) “That song understood how I was feeling”: I completely lost interest in music”: music’s place in psycho-oncology. IAMM 41-42.

O’Callaghan C, A Baird N and Michael N. (2015) “A useful icebreaker” or “jumping the gun”: Examining the usefulness of the vignette technique in cancer specific advance care planning. BMJ Supportive and Palliative Care 5(Suppl. 2): A15.

Conference abstracts

O’Callaghan C. “That song understood how I was feeling”: The contribution of music and music therapy to psychooncology. Annual Lecture in Psycho-oncology, Melbourne, October, 2015.

O’Callaghan C. Music therapists’ objectivist and constructivist research in cancer care: interventions and outcomes. Society for Integrative Oncology’s 12th International Conference. Music Therapy Symposium, Boston, November 2015.

O’Callaghan C. Expanding music’s integration in psychooncology: Reflections on music therapy and music medicine.

Mental Health Professionals’ Network Melbourne Psychooncology Network Meeting (with Margaret Ross), April 2016.

O’Callaghan C. “That song understood”; “I completely lost interest in music”: Music’s place in psycho-oncology.

International Association for Music and Medicine 3rd Annual Conference. Beijing, China, June 2016.

O’Callaghan C. Music therapy in palliative care. Beijing Central Conservatory of Music, China, June 2016.

Book chapters O’Callaghan C and Magill L. (2016) Music therapy in adult oncology in Edwards, J (ed.) Oxford handbook of music therapy, Oxford University Press, London.

O’Callaghan C and Michael N. (2016) Music therapy in mourning in Edwards, J. (ed.) Oxford Handbook of Music Therapy, Oxford University Press, London.

Reports Moloczij N, Krishnasamy M, Butow P, Castle D, Couper J, Dabscheck A, Dwyer J, Gough K, Hack TF, Hocking A, Jefford M, Judd F, Lethborg C, Mileshkin L, O’Callaghan C, Pollard A, Searle G, Snyder R, Stafford L and Schofield P. Advancing consultation recall and understanding: Solving the barriers and facilitators to intervention implementation – Final report for Victorian Comprehensive Cancer Centre. 1-30 (Peter MacCallum Cancer Centre, Melbourne, 2016).

Michael N, O’Callaghan C and Brooker J. Palliative care staff views about a change to a model of early integration of specialist palliative care: Work-life and organisational implications. 13th Australian Palliative Care Conference, Melbourne, September 2015.

O’Callaghan C. Music therapy in cancer and palliative care.

40th Anniversary of the Australian Music Therapy Association Victorian Branch Symposium. Music Therapy in Cancer and Palliative Care. Melbourne, July 2015.

O’Callaghan C. Presentation on Catholic Ethics Awareness at Cabrini. Catholic Health Australia National Conference.

Canberra, August 2015.

O’Callaghan C. 3rd Australian Palliative Care Research Colloquium, Palliative Care Research Network. Recruitment in Qualitative Research in Palliative Care, Melbourne October 2015.

O’Callaghan C. Peter Meese Memorial Lecture, Cabrini Health. Music Therapy in Palliative Care, March 2016.

O’Callaghan C, Baird A and Michael N. “A useful icebreaker” or “jumping the gun”: Examining the usefulness of the vignette technique in cancer specific advance care planning.

5 th International Society of Advance Care Planning, (presenter), Munich September, 2015.

Ross D, Villemagne-Sanchez L, Hall K, Gough K, Kashima Y, O’Callaghan C, Seymour J and Schofield P. (2016) Factors that influence patient willingness to attempt treatmentfree remission in chronic myeloid leukaemia. European Hematology Association Learning Centre, June 2016.

Ross D, Villemange Sanchez L, Schofield P, Gough K, O’Callaghan C, Seymour J, Hall K and Kashima Y. Factors that influence patient willingness to attempt treatment-free remission in chronic myeloid leukemia. 21st Congress of the European Hematology Association, Copenhagen, June 2016.

CABRINI MONASH UNIVERSITY DEPARTMENT OF SURGERY THE FRÖHLICH WEST CHAIR OF SURGERY Publications Bishop DP, Clases D, Fryer F, Williams ED, Wilkins S, Hare DJ, Cole N, Karst U and Doble PA. (2016) Elemental bio-imaging using laser ablation-triple quadrupole-ICP-MS. Journal of Analytical Atomic Spectrometry 31: 197-202.

Dat A, Chin M, Skinner S, Farmer C, Wale R, Carne P, Bell S and Warrier S. (2015) Botulinum toxin therapy for chronic anal fissures: where are we at currently? ANZ Journal of Surgery. DOI 10.1111/ans.13329.

Huang S, Theophilus M, Cui J, Bell SW, Wale R, Chin M, Farmer C and Warrier SK. (2015) Colonic transit: what is the impact of a diverting loop ileostomy? ANZ J Surg. doi: 10.1111/ ans.13376.

Jarde T, Kass L, Staples M, Lescesen H, Carne P, Oliva P, McMurrick P and Abud H. (2015) ERBB3 positively correlates with intestinal stem cell markers but marks a distinct non proliferative cell population in colorectal cancer. PLoS One 10(9):e0138336.

Parsiot JP, Thorne H, Fellowes A, Doig K, Lucas M, McNeil JJ, Doble B, Dobrovic A, John T, James PA, Lipton L, Ashley D, Hayes T, McMurrick P, Richardson G, Lorgelly P, Fox SB and Thomas DM. (2015) “CANCER 2015”: A prospective population-based cancer cohort – Phase I: Feasibility of genomics-guided precision medicine in the clinic. Journal of Personalized Medicine 5: 354-369.

Stevenson AR, Solomon MJ, Lumley JW, Hewett P, Clouston AD, Gebski VJ, Davies L, Wilson K, Hague W, Simes J; ALaCaRT Investigators. Collaborators (93): Stevenson A, Solomon M, Hewett P, Lumley J, Clouston A, Wilson K, Simes J, Hague W, Gebski V, Stevenson A, Lumley J, Stitz R, Coates A, Gurney H, Do V, Marschner I, Clouston A, Stevenson A, Lumley J, Stitz R, Davies L, Gebski V, Hague W, Pike R, Roff K, Silvester S, Simes J, Wilson K, Lumley J, Herron E, Stevenson A, Seeto A, Herron E, Morgan M, Linden S, Richardson A, Mallary S,

McIntyre A, Wong R, Solomon M, Donovan S, Hayes J, Menzies E, White S, Lawless J, Petersen D, Seeto A, Herron E, Meade B, Seeto A, Herron E, Eglinton T, Dixon L, Hulme Moir M, Nisbet S, Clark D, Seeto A, Herron E, Lee P, Donovan S, Taylor D, Seeto A, Von Papen M, Herron E, Bell S, Oliva K, Chow C, Seeto A, Evans J, Gagliano S, Heriot A, Bulger S, Thorp T, Tonkin D, Page S, Leopardi L, Hewett P, Page S, Leopardi L, Draganic B, Carroll R, Merrie A, Menzies E, Karatassas A, Page S, Leopardi L, Smith S, Carroll R, Warrier S, Bulger S, Thorp T, Ellis-Clark J and McCourt J. (2015) Effect of laparoscopic-assisted resection vs open resection on pathological outcomes in Rectal Cancer: The ALaCaRT Randomised Clinical Trial. JAMA. 2015 Oct 6; 314(13):1356-63. doi: 10.1001/jama.2015.12009.

Wilkins S. Suturing in small-group settings: A modification to Peyton’s four-step approach. Cabrini Research Day, October 2015.

Wilkins S, Haydon A, Porter I, Oliva K, Staples M, Carne P, McMurrick P and Bell S. (2016) Complete pathological response after neoadjuvant long course chemoradiotherapy for rectal cancer and its relationship to the degree of T3 mesorectal invasion. Diseases of the Colon and Rectum.

59(5): 361-368.

Wilkins S. Oncologic outcomes after standard abdominoperineal resection – Do we need to change technique? Cabrini Research Day, October 2015 and Cabrini Brighton Research Day, November 2015.

Yap R, Wilkins S, Oliva K and McMurrick P. (2016) Colorectal cancer surgery in the new extremes of age: nonagenarians.

Diseases of the Colon and Rectum. 59(6): 501-507.

Wilkins S. Colorectal Cancer Surgery in the new extremes of age: Nonagenarians. Cabrini Research Day, October 2015.

Wilkins S. Oncologic outcomes after standard abdominoperineal resection – Do we need to change technique? Cabrini Research Day, October 2015 Wilkins S. Complete pathological response after neoadjuvant radiotherapy for rectal cancer and its relationship to the degree of T3 mesorectal invasion. MPCCC Cancer Forum, Melbourne, October 2015.

Wilkins S. Colorectal cancer surgery in the new extremes of age: nonagenarians. MPCCC Cancer Forum, Melbourne, October 2015.

Conference abstracts

Wilkins S. “Oncologic outcomes after standard abdominoperineal resection – Do we need to change technique?” RACS ASC, Brisbane, May 2016.

Bell S. Workshops: “taTME – How to do it” and “For advanced laparoscopic solutions in colorectal resection surgery”. RACS ASC, Brisbane, May 2016.

Yap R. Colorectal Cancer surgery in the new extremes of age: nonagenarians. 15th Congress of the Asia Pacific Federation of Coloproctology, Melbourne, October 2015.

McMurrick P. Launch of the National Bowel Cancer Screening Program GP Education Series. Cabrini Health, October 2015.

Wilkins S. Complete pathological response after neoadjuvant radiotherapy for rectal cancer and its relationship to the degree of T3 mesorectal invasion. Alfred Health Research Week, Melbourne, October 2015.

Wilkins S. Colorectal cancer surgery in the new extremes of age: nonagenarians. Alfred Health Research Week, Melbourne, October 2015.

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Cabrini Institute Council The Cabrini Institute Council is responsible for developing, supporting and promoting the clinical education and research activities of Cabrini. The group brings a broad range of clinical and managerial experience to the Cabrini Institute Council’s governance role.

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Professor Peter Fuller AM Member since June 2005, Chair from May 2014

Dr Emma Baker Invitee since July 2015

Peter is a National Health and Medical Research Council Senior Principal Research Fellow at Prince Henry’s Institute of Medical Research in Melbourne where he is Associate Director and Head of the Steroid Receptor Biology Group. He is Director of the Endocrinology Unit at Monash Health and Adjunct Professor in Medicine and Biochemistry and Molecular Biology at Monash University. Peter’s research interests include understanding the molecular mechanisms of adrenal steroid hormone action and the molecular pathogenesis of endocrine tumours.

Emma joined Cabrini in May 2015 as the Manager of Research Programs. Emma has a research background in epigenetics and pre-clinical testing in cancer models and is a previous recipient of National Health and Medical Research Council and Cure Cancer Australia Fellowships.

Emma’s role includes organising the annual Cabrini Research Day and undertaking activities to strengthen the reputation of the Cabrini Institute and maximise its funding opportunities. Emma works closely with the Cabrini Monash University Department of Medical Oncology, the Szalmuk Family Department of Medical Oncology, in managing the clinical trials research activity.

Professor Leanne Boyd Invitee from September 2014, Member since September 2015 Leanne leads the Cabrini Institute, having joined the Executive Committee in August 2014 as Executive Director of Nursing and Cabrini Institute. She has a clinical background in critical care and began working at Cabrini in 2012 as Director of Education and Staff Development.

Leanne has more than 20 years’ experience in health professional education. Previously, she worked at Monash University as Director of Academic Programs (Middle East) and Head of Department Community Emergency Health and Paramedic Practice. Leanne holds postgraduate qualifications in education and critical care from Monash University and a Master of Tertiary Education Management from the University of Melbourne.

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Sam Low Invitee from May 2015

Kellie-Ann Jolly Member since September 2012, retired March 2016

Associate Professor Doug Lording Member since September 2008, retired July 2016

As Cabrini’s Finance and Treasury Manager, Sam is responsible for Cabrini’s financial accounting, compliance and treasury. He has been a Chartered Accountant for 13 years and has a Graduate Diploma in Applied Finance from the Financial Services Institute of Australasia.

Previously, he was the Corporate Finance Manager at a national logistics company jointly owned by Australia Post and Qantas. Prior to that, he worked at professional services firm Deloitte.

Kellie-Ann has worked in health promotion for almost 20 years. She has held the roles of senior policy advisor with the Victorian Department of Health, tertiary lecturer in health promotion, and Director Physical Activity and Healthy Eating at the Victorian Health Promotion Foundation (VicHealth). Since August 2008, Kellie-Ann has been the Director Cardiovascular Health at the Heart Foundation (Victoria) where she manages the health programs which aim to prevent death and disability from heart disease. She has a Graduate Diploma in Health Promotion and a Master of Health Sciences (Health Promotion).

Doug is an endocrinologist and andrologist in private practice at Cabrini. From 1992-2007, he was Medical Director at Cabrini. His specialities include diabetes, general endocrinology and male reproductive medicine.

Doug has extensive clinical trial experience and is an Honorary Clinical Associate Professor of Medicine at Monash University. He is a Fellow of the Royal Australasian College of Physicians, a Board member of Andrology Australia and a member of the scientific advisory committee for Foundation 49: Men’s Health.

C A B R I N I I N S T IT U T E CO U N C I L

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Jeremy McCarthy Member since February 2007

Professor Meg Morris Member since February 2015

Professor Robyn O’Hehir AO Member since September 2010

Jeremy is a partner at national law firm HWL Ebsworth in its mergers and acquisitions group in Melbourne. He has extensive experience in corporate governance and general commercial matters and has drafted a broad range of commercial contracts. Jeremy advises clients in a range of industries, in particular the health sector.

Professor Meg Morris is a physiotherapist and fellow of the Australian College of Physiotherapists. She is Head of the School of Allied Health at La Trobe University, an Honorary Professor at Cabrini and an Honorary Professor at Melbourne Health. She is an international expert in ageing and neurological conditions such as Parkinson’s disease and is widely published. Professor Morris is known for her work on physical activity, exercise and dancing for people with Parkinson’s disease, as well as physical activities and strength training. She has strong international research collaborations in Italy, Ireland and Singapore.

Robyn is Professor/Director Allergy, Immunology and Respiratory Medicine, Central Clinical School, Monash University and Alfred Hospital, Deputy Head, Central Clinical School, Monash University and Deputy Head Research, Alfred Health. She is a consultant physician, educator and internationally renowned researcher in allergy and anti-inflammatory therapies with substantial grant support from the National Health and Medical Research Council. Robyn was elected a Fellow of the Australian Academy of Health and Medical Sciences and a Fellow of the Thoracic Society of Australia and New Zealand in 2015 and she was made an Officer of the Order of Australia in 2016. Robyn is a Life Governor of Asthma Victoria and a member of Council of the Sir Robert Menzies Memorial Foundation.

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Sue Parkes Invitee since July 2015

Associate Professor John Santamaria Member since August 1996

Professor Julian Smith Member since July 2015

Sue Parkes, Director of the Cabrini Foundation, has more than 20 years’ experience working in not-forprofit organisations including some of Australia’s leading non-government organisations. Sue has held leadership roles at Melbourne City Mission, Sacred Heart Mission, Brotherhood of St Laurence and Eastern Health. She has a strong commitment to social justice and is currently on the Board of the Fitzroy Learning Network.

John is the Director of St Vincent’s Hospital Melbourne’s Intensive Care Unit. He is National and State President of the Australian and New Zealand Intensive Care Society.

John was a member of the Cabrini Board of Directors for many years and served as Vice Chairman from September 2005 until October 2009.

Julian is Head of the Department of Cardiothoracic Surgery at Monash Health, Head of Monash University’s Department of Surgery (School of Clinical Sciences at Monash Health) and Deputy Head of the School of Clinical Sciences at Monash Health. He has served as a Councillor of the Royal Australasian College of Surgeons. Julian is a consultant cardiothoracic surgeon at MonashHeart and has broad basic and clinical research interests in robotic and minimally invasive surgical techniques, acute kidney injury after cardiac surgery, utilising large databases to monitor patient outcomes and in surgical education.

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Natalie Sullivan Member since July 2015, retired July 2016

Dr Michael Walsh Member since December 2008

Professor Neville Yeomans Member since February 2010

Natalie joined Cabrini in 2010 and oversees five clinical campuses including our acute hospital in Brighton, palliative care, two rehabilitation hospitals, residential aged-care and Cabrini’s chronic disease programs. In 2012, Natalie assumed executive leadership for patient experience. Her background is in allied health as a prosthetist/orthotist. She is recognised as a Fellow of the Australasian College of Health Service Management, holds a Master of Health Administration, and is a graduate of the Australian Institute of Company Directors. Prior to joining Cabrini, Natalie worked in public health in executive and general management roles leading groups of hospitals and network-wide health services.

Michael has been Chief Executive of Cabrini Health since 2008. He has a distinguished career in hospital and health administration in Victoria, Western Australia, the UK and the Middle East. He is a medical graduate of Monash University and holds a Master in Public Administration from the Kennedy School of Government, Harvard University. Michael is a Fellow of the Royal Australasian College of Medical Administrators and the Australasian College of Health Service Managers.

Neville is Director of Research at Austin Health and Emeritus Professor of Medicine (previously Foundation Dean) in the School of Medicine, University of Western Sydney. He is a gastroenterologist and a fellow of the Royal Australasian College of Physicians, American College of Gastroenterology and American Gastroenterological Association. Neville’s research has been mainly into the biology and pathology of the gastric mucosa, pharmacology of acid-related diseases and recently, medical education.

CABRINI SUPPORTERS Companions

Lady Patricia Connelly

Mrs Kerrie Hunter & Family

Aventis Pharma Pty Ltd

Construction Engineering (Aust) Pty Ltd

Mrs Dinah Krongold & Family

Mr John Gandel AO & Mrs Pauline Gandel

Equity Trustees Limited

Dr Laurence LeWinn Foundation

Mr Ian & Mrs Linda Gandel

Marc & Bev Fookes

Kylie Minogue OBE

Ms Michelle Gandel

Charles Holckner & Family − In Memory of Lily

Richard & Susan Mizgala

Mr Tony & Mrs Helen Gandel

Harold Johnston OAM & Kay Johnston AM

Frank O’Shea OAM

Heartbeat Cabrini Inc.

Jreissati Foundation

The Family of Duncan Powers

Mr Alan Jackson AO & Mrs Esme Jackson

Susan Kavals Memorial

In Memory of Marlene Regan

Alan Jackson Nursing Research Fellow

Mr David & Mrs Barbara MacDonald

The Sasse Family

Mr John Laidlaw OAM & Mrs Betty Laidlaw

Mr Angus Mackay

Mr & Mrs P Selzer & Family

Mr David Mandie OBE

Mr Louis Managan AO & Cecile Mangan

Signorino Family

Pfizer Australia Pty Ltd

The McMurrick Family

Neville & June F.M. Smith

Merrin Foundation

Peter Meese Cancer Nursing Fund

Victor Smorgon Charitable Fund

Nigel Peck AM & Patricia Peck

Mr & Mrs Mark Newman

Mr Brian J Sutton FCNA

The Moniek Sambor Family Memorial Research Fund

Richard & Dorothea Nossbaum

David & Chasya Tamir

The Sambor Family

Ostomy Association of Melbourne Inc

PF & RA Tomaino

The Simonds Family

Alan, Ada & Eva Selwyn Family

Michael & Donna Tricarico & Family

The Stewardson Charitable Trusts

Richard Smith

Cheryl M Windsor

Fellows

Benefactors

Associated Retailers Limited

Amgen Australia Pty Ltd

The Bachrach Charitable Trust

AMP Foundation

Anthony & May Barry

AON Risk Services Australia

In Memory of Jan Bucknall

Beaconsfield & de Winter Families

Charter Security Group

Bib Stillwell BMW

Maureen Coomber

W & G Bradshaw Trust

The Alfred & Jean Dickson Foundation

Collier Charitable Fund

Partners

The Fryer Family

Bensons Group of Companies

Prue Gillies AM

Commonwealth Bank of Australia – Corporate Financial Services Vic & Tas

The Michael & Andrew Buxton Foundation

Geoff and Helen Handbury Foundation

The De Luca Family

Cabrini Medical Staff

Mr & Mrs Higgins

David & Kristene Deague

Mr George & Mrs Mira Szalmuk Szalmuk Family Department of Medical Oncology Mrs Anne Wollach-Szalmuk Mr Geoff Szalmuk Mrs Simone Szalmuk-Singer Dr David & Mrs Lisa Thurin Mr & Mrs Joseph & Helena Frőhlich West Frőhlich West Chair of Surgery

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CABRINI SUPPORTERS

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Mr Andrew C Facey

Gary Richardson

Ron Bunker & Evelyn Abaya

Mr Geoff & Mrs Lesley Freeman

Roche Products Pty Ltd

Reginald & Audrey Campbell

Brian Goddard

Irvin Rockman CBE

Caravan Industry Australia Victoria Trades Division

Ken Grenda AM & Margaret Grenda

In Memory of Mrs Bella Rogers

Chris Chadwick

Mr John Grossi

Rotary Club of Brighton

John Christophersen

Herschel Asset Management Limited

Rotary Club of Malvern

Estate of Mrs Margaret Cochrane OAM

Mr Russell Hutchinson

The Sanford Partnership

Naja David & Family

IM & SK Families Fund - suggested

Sanofi-Sythelabo Australia Pty Ltd

Dr Bruce & Mrs Pat Davis

Des & Cheri Jackson

The late John Saunders AO

Downie Family

Jack & Sheila Jenner

Margaret Savill

Mary Drenen

Kay & Burton Pty Ltd

Alexander Slade

The Duggan Foundation

Eleanor Keamy & George Tate

The Brian Smith Endowment

Mr & Mrs Wal Edgar & Family

Mrs Judith Lang & The Gideon Lang Foundation

Smith & Nephew Pty Limited

The Marian & E H Flack Trust

Jeff Loewenstein

Margery E Snowball

Fried & Sable Families

Helen Macpherson Smith Trust

Sotheby’s Australia

Gailey − Lazarus Foundation

Mr Colin & Mrs Jannene Madden

Spooner Family

Mr Michael & Mrs Helen Gannon

The Matthey Family

G & K Stansen

Eli & Kerry Goldfinger

Alison McElroy

Tattersall’s, The Estate of The Late George Adams

Grenda Foundation

M McGauran

Mr Stewart & Mrs Ingrid Webster

Dorothy Haines

Ron & Valerie McLaughlan

Dr Charles William (Bill) Edgar Wilson

The Hall Family

MIA Victoria

Windemere Foundation

P & M Harbig (Holdings) Pty Ltd

Doris Mohl OAM

Cheryl M Windsor

The George Hicks Foundation

John Allison Monkhouse

Yarra Valley Travel

Dr & Mrs R A Hurley

Mr Hugh Morgan AC & Mrs Elizabeth Morgan Mr Patrick Nalty The O’Donohue Family Paulusz Family Foundation Pharmacia Australia Pty Ltd Prostate Cancer Foundation of Australia Elinor Rabinov Margaret & Tony Reeves Lady Susan Renouf

Patrons Aquanita Racing Pat & Sheril Aughterson Bagot Gjergja Foundation Eric Ormond Baker Charitable Fund Mr Nick & Miss Angela Baldi Theodore (Ted) & Miriam Berman Besen Family Foundation

The Irvine Club Inc Jacobs Thomas & Associates Dr Sharon Keeling Mr Doug Kefford AO The Valda Klaric Foundation Langton’s Pty Ltd Annie Rose & Andrew Lazar Foundation Lynette & Kevin Lee Mrs Barbara J Lewis

The Lochtenberg Family

In Memory of Suzanne Vass

Mr & Mrs Simon & June Lubansky

Lord Mayor’s Charitable Fund

Peter T. Wain & Family

Ron & Fay Malouf

Joan Loton

The Wallis Family

Allan McNicol

The Lowthian Family

Marie & John Warnock

Desmond W Milner

Men of Malvern

Mr Choo Keng Wee & Mrs Beverley Anne Wee

In Memory of Judith Moir

Andy Lyas

The Werled Foundation

E. Morris

Christopher Marriott In Memory Of Leigh Masel The Mezo Family Gordon Moffatt AM Barry & Beatrice Moignard Charitable Trust Mr Bill Montague OAM & Mrs Elaine Montague Montague Group R M Morgan AM Paul Mullaly QC Mr John & Mrs Pamela Murphy Richard (Frederick) O’Brien Bruce Parncutt & Robin Campbell Proclaim Management Solutions Pty Ltd Ramler Family John Reeves Mr Benedict J Roche Denis Roche Drs Sue & Phil Ronaldson Rotary Club of Brighton Charitable Foundation Rotary Club of Chadstone/East Malvern Peter & Barbara Shearer Mr John Sircom & Mrs Helen Sircom Mr Daryl Somers OAM & Mrs Julie Somers OAM In Memory of Margaret Roff Sutton Mrs Valma Truin Barbara Tucker

Associates John & Ruth Adamson Georgina Barraclough John & Liz Bate Mr & Mrs Jack & Meg Bowen Brighton Grammar School David Brookman The Sir Wilfred Brookes Charitable Foundation Mr & Mrs G & J Brown Carter Family Foundation Stephen Charles Nelson & Julie Cheung celebrating our 50th Anniversary In Memory of Ignatius Paul Cini Cobram Barooga Golf Club Veterans Club Mrs Margaret Coningsby/In Memory of Graham Coningsby In Memory of Ron & Joan Davies Brian Davis Dromana Football & Netball Club Mrs Susie Edwards & Family John Graham Mr & Mrs Geoffrey A Grant Edith Greiman Peter Heffernan Jean & Ern Ireland − Sea Bee Pty Ltd Mr Andrew Lindsay

Mr Vincenzo Paoletta Armando Poli Lyn Punter Mrs Irene Reich Ralph & Ruth Renard Dr John Rogers AM & Mrs Rogers Richard & Ros Rogers The Russell Foundation Pamela Shotton − In Memory of John Shotton Yvonne Spencer The Springwaters Foundation Jean St Leger Educational Scholarship Mr & Mrs Frank & Heather Stewart The Strachan Family Mr Bernard Sweeney Geoffrey H Thomas Leonie Thompson Yvonne Thompson Joan And Roderick Thomson Cornelis Van Ek Alice Vaughan B & A Wain Mr Max Walters Marcia Williams

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CABRINI SUPPORTERS

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Bequests

Estate of Heather Jones

In Memoriam

In Memory of Claire Abrahams

Estate of Valda Irene Keil

Mr Christopher Bedelis

Estate of Gustav G.H. Apituley

Estate of Irene Kozica

Dr Katrina Bottomley

Estate of Ellen M Balderstone

Estate of Robert Mackey

John William Clapham

Estate of Nola Barnes

In Memory of Mrs Katherine Jane Mactier

In Memory of Graham Coningsby

Estate of Carmel Mary Blanton

Rita Anversa Magris

Nereo Dizane

Estate of Doris Elaine Boyd

Estate of Brian Charles Mander

Kevin Elias

Mrs Ann Brewer

Estate of Katherine Mander

Walter Lyle Fish

Estate of Rosina Violet Brown

Estate of June Masson

Margaret Goddard

Estate of Nance Nevasa Buchanan

In Memory of Kiril Miltenov

Peter Royston Gray

Estate of Agnes Ferguson Clark

Estate of Marita Therese Mulcahy

The Tom Hafey Memorial Fund

Estate of Annie Marjorie May Clarke

Estate of Marjorie May Murdoch

Jade Howell

Roger John Cleary

Estate of Rex Oxnam

Kerrie Hunter

Estate of Joyce Mena Coxall

Estate of Leslie Charles Parkinson

Patricia Janes

The Estate of David Roy Cross

Estate of Russell Pitt

Tessa Kagan

Estate of John Lawrence De Yong

Estate AV Powers

George Karpathiou

Rino Della Bosca

Estate of Lindsay G Quinn

Stephen Kelly

Estate of John Robert Edwards

Estate of William Clifford (Peter) Rawlins

Dorothy Keyte

Estate of Dr Betty Elliott

Estate of Alexander Graeme Robertson

Tuen Yee Lucy Lao

Estate of Barbara Feil

Estate of Anthony Carmel Saccasan

Patsy Littlejohn

In Memory of Hubert Frances & Margaret Mary McCarthy

Estate of Grace Saunders

Dr Angela Marks

Estate of Harold Francis

Mrs E C Seccull

Judtih Moir

Estate of U M Frawley

Estate of Alan Selwyn

Mary Nesbitt

Estate of Dorothy Cecelia Garbutt

Estate of Leslie Alfred Shapland

Mr Chor-Kim Ng

Estate of John Sutherland Hamling

Estate of Carl & June Simpson

Mr Brian O’Sullivan

Estate of Pamela Mary Harper

Estate of Maria (Lina) Concetta Sinelli

Maxwell Charles Parsons

Estate of Noel Arthur Hatherly

Bella Taft

Mrs Christine Potts

Estate of Mary Kathleen Hauser

Estate of Hugh L Wallace

Joyce Reed

Estate of Doris Mary Hawkless

Estate of Wilma Elsa White

Elian Rotenberg

The Estate of Rita Mae Hunt

Estate of Betty Geddes Wood

Timothy Russell

Estate of Doreen Johnson

The Estate of Vica Vitea Yavitch

Ann Ryan

In Memory of Richard John Savill

KEY PARTNER S OF TH E C ABRI NI I NSTI T UTE

Marjorie Smith Diane Spielvogel In Memory of George & Mira Szalmuk − The Szalmuk Family Charlotte Tait Mrs Pamela Tan Geoffrey Robin Westacott Education and research Brian H. Gillies Palliative Care Research Fund Brian H. Gillies Travel Scholarship for Palliative Care Nurses Mayer Page Research Fellow Sarah Miskin Palliative Care Nursing Scholarship John Allison Monkhouse Palliative Care Scholarship

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C A BR I NI M I S S I ON

TH E C ABRI NI I NSTI T UTE MI S S I ON

Who we are: We are a Catholic healthcare service inspired by the spirit and vision of Saint Frances Xavier Cabrini and the Missionary Sisters of the Sacred Heart of Jesus.

The Cabrini Institute is committed to improving the clinical outcomes of patients of Cabrini. It embraces the mission, values and vision of Cabrini and works within an ethical framework. The Cabrini Institute has a vital role in helping Cabrini to achieve its vision – that is:

What we believe: We are a community of care, reaching out with compassion, integrity, courage and respect to all we serve.

What we do: We provide excellence in all of our services and work to identify and meet unmet needs.

C A BR I NI VA LUE S

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Our values form the base of our mission, are built around what we believe and drive how we act. They are drawn from Saint Frances Xavier Cabrini’s life and reflect her heart, her spirit, her conviction and her approach.

Compassion: Our drive to care is not just a professional duty to provide excellent quality care but is born of a heartfelt compassion for those in need, motivated by God’s love for all people.

Integrity: We believe in the power of hope to transform people’s lives and remain faithful to the bold healing mission and legacy of Saint Frances Xavier Cabrini.

Courage: We have the strength, determination, vision and conviction to continue the work of Mother Cabrini and the Cabrini Sisters.

Respect: We believe that every person is worthy of the utmost respect and the best possible healthcare.

We know that our resources are entrusted to us to use for the benefit of others.

“By understanding and addressing the needs of our community, we will grow by learning – by researching and continuously improving the quality of our care and by motivating staff committed to our healthcare mission to provide excellence in all of our services . . . we will enhance health and quality of life by working with our patients and their families to anticipate, prevent and ease suffering.”

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Published September 2016.

Designed by Motion Advertising & Design Pty Ltd. Printed by Adams Printers Pty Ltd. Printed on Grange Laser/Offset, which is PEFC certified and manufactured in a facility with ISO 14001 EMS accreditation. Made elemental chlorine free.

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C ABRINI INSTIT UTE 154 Wattletree Road Malvern Victoria 3144 Australia email: cabinstevents@cabrini.com.au www.cabrini.com.au