Thermella™ relieves hot flashes and night sweats at the source by blocking the neurokinin B (NKB) pathway
Relieve your patients' hot flashes with NKBblocking Thermella
Thermella is a patented neurokinin 3 receptor (NK3R) antagonist that blocks NKB to deliver non-hormonal relief from hot flashes and night sweats.1,2
97% experienced improved quality of life.6
NKB LEVELS IN A PRECLINICAL STUDY
“POSTMENOPAUSAL”
The ingredients in Thermella's patented formula synergistically block NKB while also reducing NKB to premenopausal levels.1,2
A POOLED ANALYSIS OF TWO RANDOMIZED, DOUBLE-BLIND,
Thermella™ works as early as two weeks and over 95% of patients see VMS improvement by week 12.
Thermella™ is safe and non-hormonal
No significant changes in kidney and liver function observed in a double-blind, placebo-controlled trial and a preclinical study. This includes no changes in levels of ALT, AST, and bilirubin.5,6
In an in vitro study...
Thermella produced no proliferationof MCF7 breast cancer cells, which are dependent on interaction with estrogen receptors.4
Thermella showed no impact on measurements of estrogen or progesterone, and did not increase uterine weight.5 In a preclinical study...
Thermella demonstrated no significant difference in estradiol levels.6 In a randomized, double-blind, placebocontrolled trial...