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TableTheWHOclassicationofneuroendocrineneoplasmsoftheheadandneck[17]Well-dierentiatedNeuroendocrineCarcinoma(CarcinoidTumor)
Moderately-dierentiatedneuroendocrinecarcinoma(atypicalcarcinoid)Poorly-dierentiatedneuroendocrineSDCisaclinicallyaggressivecancerwithhighriskof localrecurrenceanddistantmetastases,however,withachanceofcuringofaround%,andaradicalsurgicaltreatmentisnecessaryduetothehighclinicalstageof ThepublicationofthenewWHOclassificationofheadandnecktumoursinbroughtmajormodificationsAccesstheWHOClassificationofTumoursonline,also knownastheBlueBooks,forauthoritativeandupdatedinformationonhumantumourssomadetoadoptsimilarnomenclatureandclassificationofentities commonlyincludedinotherWHOtumorclassifica-tionsofdifferentorgansEspecially,anewchapterisdedicatedtotheoropharynx,focusingonthedescription ofsquamouscellcarcinomainducedbythevirusHumanPapillomaVirus(HPV),andnewentitiesoftumorsarTheWorldHealthOrganization(WHO) ClassificationofHeadandNeckTumors(“BlueBook”)willnowincludeanewchapterontumorsandtumor-likelesionsoftheneckandlymphnodes,which SimilartotheWHO,thecodificationofhematopoieticandlymphoidneoplasmsoftheheadandneckisincludedwithinchapterspertainingtothenasalcavityand paranasalsinuses,thenasopharynx,thelarynx,theoralcavityandoropharynx,theinthenewWHOClassicationofHeadandNeckTumours(Table2)[21]This isparticularlynotableintheThenewWHOclassificationfollowstheIARC/WHOnomenclatureframeworkandrestrictsthediagnostictermofneuroendocrine carcinomatopoorlydiferentiatedepithelialTheWorldHealthOrganization(WHO)ClassificationofHeadandNeckTumors("BlueBook")willnowincludea newchapterontumorsandtumor-likelesionsoftheIn,thelatestrevisiontotheWHOClassificationofHeadandNeckTumourswillbereleased