2019/3/13
Recombinant Human Hyaluronidase PH20
www.creative-enzymes.com
Description Recombinant Human Hyaluronidase PH20 belongs to a family of enzymes that catalyze the degradation of hyaluronic acid (HA). The enzyme is effective to hyaluronic acid in the extracellular matrix (ECM) and promote the diffusion of extracellular substances.
Product Information
Cat No. NATE-1923
Endotoxin: ≤10 EU/ml
EC No. EC 3.2.1.35
Storage: -20 °C
CAS No. 37326-33-3
Control Tests: Laboratory of QC
Species: Human
Appearance: Sterile lyophilized powder,
Source: CHO
dissolved in pure water to form a clear, colorless to pale yellow solution. Must not
Purity: ≥99%
contain visible insoluble matter.
Activity: ≥12,000 IU/vial
Highlights Creative Enzymes® Hyaluronidase PH20 shows several advantages over similar products on the market: Creative Enzymes® HAase PH20
Similar Products on the Market
Species
Human
Animal
Source
CHO cell
Testis
Technology
Recombinant DNA
Extraction
Purity
≥99%
Low
Applications Oncology
Pharmacokinetics
PH20 degrades HA in tumor cells
PH20 hydrolyzes hyaluronic acid and
coating, which may result in the
increases diffusion of injected drugs, thus
inhibition of tumor cell growth.
facilitating their absorption.
Enzymatic degradation of ECM HA with
PH20 can be used as an adjunct in
PH20 is associated with remodeling of
subcutaneous urography to improve
the tumor stroma, reduction of tumor
resorption of radiopaque agents.
interstitial fluid pressure, and expansion of tumor blood vessels, resulting in facilitated delivery of anti-cancer
Scientific Research
agents. ELISA; SDS-PAGE; Western blot.
Note: Our products are not intended for private therapeutic use!
Tel: 1-631-562-8517 Fax: 1-631-938-8127
Contact Information
E-mail: info@creative-enzymes.com
Address: 45-1 Ramsey Road, Shirley, NY 11967, USA
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