Action of Cardioselective beta blockers naturevitaminsa.blogspot.com/2019/10/action-of-cardioselective-beta-blockers.html
What is the Cardioselective beta-blockers Cardioselective beta-blockers are selective beta-adrenergic blocking agents that preferential block the beta-1 receptors only and prevent their stimulation.Beta-1 androgenic receptors are located on the nerve ending of the sympathetic nervous system and in the kidney, eye. Beta-adrenergic blocking agent blocks the stimulation of the heart by inhibiting the binding of epinephrine (adrenaline) and nor-epinephrine (non-adrenaline) hormone to the Beta-1 receptors located on the nerves.
adrenaline hormones are released by the adrenal gland and some neurons. its main function is to increase heartbeat, blood pressure, enlarge the pupil of the eye and expanding the air passage of the lungs. Cardio selective beta-blockers will always block beta 1 receptors or prevent stimulation by inhibiting the Cardioselective beta-blockers: Anxiety(fear) binding of hormones with the beta 1 receptor. By inhibiting stimulation, they reduce blood pressure, heart rate, cardiac output, forces of constriction, and cardiac work, which in turn reduce oxygen consumption by the heart and increase the tolerance of exercise. If they are present in excess amount then they can also block the beta-2 adrenergic receptor located in the bronchial smooth muscles of the airways, which results in an increase of bronchial resistance. cardioselective beta-blockers are more efficient in blocking beta-1 receptors than beta-2 receptors, but they are less cause bronchial constriction compared with non-selective beta-blockers.
List of cardioselective beta-blockers 1/3