5-(Aminomethyl)-1,2-oxazol-3-one hydrate (Muscimol hydrate) [C4H8N2O3]
Query Query
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Date
1 reactions in Reaxys
2018-08-03 20h:55m:46s (UTC)
H 2O HN O
1. Query
O NH 2
Search as: Product, As drawn, No mixtures ) AND (IDE.RN='305808-13-3') AND (IDE.INCHI='QYGRQAWQDLPUDKUHFFFAOYSA-N') NOT (RX.RXRN=14819161))
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2018-08-03 21:04:06
5-(Aminomethyl)-1,2-oxazol-3-one hydrate (Muscimol hydrate) [C4H8N2O3]
O O
N
HN
HN O O
HN
O
H 2O
N
NH 2 NH O
S
O
O
Rx-ID: 24338252 View in Reaxys 1/1 Yield 32%
Conditions & References 17 : 2-{2-Ethoxy-5-[(5-isoxazolin-3-onylmethyl)sulphamoyl]-phenyl}pyrido[3,2-d]pyrimidin-4(3H)-one EXAMPLE 17 2-{2-Ethoxy-5-[(5-isoxazolin-3-onylmethyl)sulphamoyl]-phenyl}pyrido[3,2-d]pyrimidin-4(3H)-one Obtained using muscimol hydrate in 32percent yield, m.p. indeterminate (amorphous solid). Rf 0.40 (dichloromethane:methanol:glacial acetic acid, 90:10:1). Patent; Cell Pathways, Inc.; US6060477; (2000); (A) English View in Reaxys
32%
17 : 2-{2-Ethoxy-5-[(5-isoxazolin-3-onylmethyl)sulphamoyl]-phenyl}pyrido [3,2-d]pyrimidin-4(3H)-one EXAMPLE 17 2-{2-Ethoxy-5-[(5-isoxazolin-3-onylmethyl)sulphamoyl]-phenyl}pyrido [3,2-d]pyrimidin-4(3H)-one Obtained using muscimol hydrate in 32percent yield, m.p. indeterminate (amorphous solid). Rf 0.40 (dichloromethane: methanol: glacial acetic acid, 90:10:1). Found: C,51.01; H,3.86; N,15.49. C19 H17 N5 O6 S requires C,51.46; H,3.86; N,15.79percent. Patent; Pfizer Inc.; US5591742; (1997); (A) English View in Reaxys
Copyright Š 2018 Elsevier Life Sciences IP Limited except certain content provided by third parties. Reaxys is a trademark of Elsevier Life Sciences IP Limited.
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2018-08-03 21:04:06