1-Phenyl-2-(piperidin-1-yl)ethane-1,2-dione [C13H15NO2]

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2018-08-10 16h:34m:32s (UTC)

O

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Search as: As drawn ) AND (IDE.XRN=1284457))

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Reaxys ID 1284457 View in Reaxys

1/1 CAS Registry Number: 14377-63-0 Chemical Name: 1-(phenylglyoxylyl)piperidine; 1-phenyl-2-(piperidin-1-yl)ethanone-1,2-dione; 1-phenyl-2-(piperidin-1-yl) ethane-1,2dione; 1-phenyl-2-(piperidin-1-yl)ethane-1, 2-dione; 1-phenyl-2-(piperidin-1-yl)ethane-1,2-dione; 1-phenyl-2-piperidin-1-yl-ethane-1,2dione; phenyl-2-(piperidin-1-yl)ethane-1,2-dione Linear Structure Formula: C13H15NO2 Molecular Formula: C13H15NO2 Molecular Weight: 217.268 Type of Substance: heterocyclic InChI Key: BWSCMJUJHSJAEV-UHFFFAOYSA-N Note:

O

N

O

Substance Label (59) Label References 9ac

Urbán, Béla; Szabó, Péter; Srankó, Dávid; Sáfrán, György; Kollár, László; Skoda-Földes, Rita; Molecular Catalysis; vol. 445; (2018); p. 195 - 205, View in Reaxys

8va

Kataoka, Kengo; Wachi, Keiju; Jin, Xiongjie; Suzuki, Kosuke; Sasano, Yusuke; Iwabuchi, Yoshiharu; Hasegawa, Jun-Ya; Mizuno, Noritaka; Yamaguchi, Kazuya; Chemical Science; vol. 9; nb. 21; (2018); p. 4756 - 4768, View in Reaxys

compound of formula 3

Patent; UNIVERSITÉ DE LIÈGE; MONBALIU, Jean-Christophe; GERARDY, Romaric; (30 pag.); WO2018/50546; (2018); (A1) English, View in Reaxys

1b

Dutta, Pratip Kumar; Dhar, Basabbijayi; Sen, Subhabrata; New Journal of Chemistry; vol. 42; nb. 14; (2018); p.

12062 - 12071, View in Reaxys

7

Wasserman, Harry H.; Lee, Kieseung; Xia, Mingde; Tetrahedron Letters; vol. 41; nb. 15; (2000); p. 2511 - 2514, View in Reaxys; Papp; Szabó; Srankó; Sáfrán; Kollár; Skoda-Földes; RSC Advances; vol. 7; nb. 70; (2017); p.

44587 - 44597, View in Reaxys

3ac

Du, Bingnan; Jin, Bo; Sun, Peipei; Organic and Biomolecular Chemistry; vol. 12; nb. 26; (2014); p. 4586 - 4589, View in Reaxys; Liu, Fuyan; Zhang, Kuan; Liu, Yanfeng; Chen, Shan; Chen, Yiping; Zhang, Dela; Lin, Chunfu; Wang, Bo; RSC Advances; vol. 7; nb. 12; (2017); p. 7158 - 7162, View in Reaxys

4ca

Wang, Dan; Zhang, Kuan; Jia, Luhan; Zhang, Danting; Zhang, Yue; Cheng, Yujia; Lin, Chang; Wang, Bo; Organic and Biomolecular Chemistry; vol. 15; nb. 16; (2017); p. 3427 - 3434, View in Reaxys

IBt

Patent; COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH; SUDALAI, Arumugam; PRASAD, Pragati Kishore; REDDI, Rambabu; (31 pag.); WO2017/77550; (2017); (A1) English, View in Reaxys

Intermediate 1

Patent; Hefei Lifeon Pharmaceutical Co., Ltd.; Pei, Lin; Li, Bing; Hu, Dejin; Chen, Jun; Gao, Meihua; Ji, Junqiu; (11 pag.); CN106349151; (2017); (A) Chinese, View in Reaxys

1c

Singh; Kirchmeier; Shreeve; Journal of Organic Chemistry; vol. 64; nb. 7; (1999); p. 2579 - 2581, View in Reaxys; Shen, Guodong; Zhao, Lingyu; Wang, Yichen; Zhang, Tongxin; RSC Advances; vol. 6; nb. 82; (2016); p. 78307 78310, View in Reaxys

3b

Zhang, Juan; Wei, Ying; Lin, Shaoxia; Liang, Fushun; Liu, Pengjun; Organic and Biomolecular Chemistry; vol. 10; nb. 46; (2012); p. 9237 - 9242, View in Reaxys; Nekkanti, Shalini; Veeramani, Karuna; Praveen Kumar, Niggula; Shankaraiah, Nagula; Green Chemistry; vol. 18; nb. 11; (2016); p. 3439 - 3447, View in Reaxys; Ramanathan, Mani; Kuo, Chun-Kai; Liu, Shiuh-Tzung; Organic and Biomolecular Chemistry; vol. 14; nb. 48; (2016); p. 11446 - 11453, View in Reaxys

3p

Zhao, Qiong; Miao, Tao; Zhang, Xiaobin; Zhou, Wei; Wang, Lei; Organic and Biomolecular Chemistry; vol. 11; nb.

11; (2013); p. 1867 - 1873, View in Reaxys; Liu, Chengkou; Yang, Zhao; Guo, Shiyu; Zeng, Yu; Zhu, Ning; Li, Xin; Fang, Zheng; Guo, Kai; Organic and Biomolecular Chemistry; vol. 14; nb. 36; (2016); p. 8570 - 8575, View in Reaxys

3m

Guo, Shiyu; Fang, Zheng; Yang, Zhao; Liu, Chengkou; Dai, Zhongxue; Zhao, Lihuan; Guo, Kai; RSC Advances; vol. 6; nb. 2; (2016); p. 1503 - 1507, View in Reaxys

5a

Sun, Zhao; Liu, Hui; Zeng, Yong-Ming; Lu, Chong-Dao; Xu, Yan-Jun; Organic Letters; vol. 18; nb. 3; (2016); p.

620 - 623, View in Reaxys

2t

Prasad, Pragati K.; Reddi, Rambabu N.; Sudalai, Arumugam; Organic Letters; vol. 18; nb. 3; (2016); p. 500 - 503, View in Reaxys

3aa

Zhang, Xueyao; Yang, Honglei; Huo, Yong; Li, Jing; Ma, Jianxin; Ma, Jiantai; Dalton Transactions; vol. 45; nb. 21; (2016); p. 8972 - 8983, View in Reaxys

6a

Meena, Samdarshi; Singh, Rohit; Vishwakarma, Ram A.; Aga, Mushtaq A.; Jain, Shreyans K.; Tetrahedron Letters; vol. 57; nb. 33; (2016); p. 3715 - 3717, View in Reaxys

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4ab

Liu, Xing-Xing; Wu, Zhao-Yang; He, Yong-Qin; Zhou, Xiao-Qiang; Hu, Ting; Ma, Chao-Wei; Huang, GuoSheng; Advanced Synthesis and Catalysis; vol. 358; nb. 15; (2016); p. 2385 - 2391, View in Reaxys

4

Dhara, Kalyan; Kapat, Ajoy; Ghosh, Tridev; Dash, Jyotirmayee; Synthesis (Germany); vol. 48; nb. 23; (2016); p.

4226 - 4268; Art.No: SS-2016-N0175-OP, View in Reaxys

2d

Yu, Lu; Somfai, Peter; Synlett; vol. 27; nb. 18; (2016); p. 2587 - 2590; Art.No: ST-2016-B0315-L, View in Reaxys

2a

Song, Bingrui; Wang, Siyuan; Sun, Caiyun; Deng, Hongmei; Xu, Bin; Tetrahedron Letters; vol. 48; nb. 51; (2007); p.

8982 - 8986, View in Reaxys; Dutta, Sayan; Kotha, Surya Srinivas; Sekar, Govindasamy; RSC Advances; vol. 5; nb.

58; (2015); p. 47265 - 47269, View in Reaxys

3a

Lamani, Manjunath; Prabhu, Kandikere Ramaiah; Chemistry - A European Journal; vol. 18; nb. 46; (2012); p.

14638 - 14642, View in Reaxys; Shao, Ying; Wu, Zhuhong; Miao, Chunbao; Liu, Li; Journal of Organometallic Chemistry; vol. 767; (2014); p. 60 - 64, View in Reaxys; Sharma, Nidhi; Kotha, Surya Srinivas; Lahiri, Nabajit; Sekar, Govindasamy; Synthesis (Germany); vol. 47; nb. 5; (2015); p. 726 - 736; Art.No: SS-2014-T0695-OP, View in Reaxys; Kotha, Surya Srinivas; Sekar, Govindasamy; Tetrahedron Letters; vol. 56; nb. 46; (2015); p. 6323 6326, View in Reaxys

BFA-PD

He, Ming-Hui; Su, Mei-Lin; Yu, Zhao-Hui; Chen, Guang-Xue; Zeng, Zhao-Hua; Yang, Jian-Wen; Chinese Chemical Letters; vol. 26; nb. 1; (2015); p. 21 - 25, View in Reaxys

13c

Mupparapu, Nagaraju; Battini, Narsaiah; Battula, Satyanarayana; Khan, Shahnawaz; Vishwakarma, Ram A.; Ahmed, Qazi Naveed; Chemistry - A European Journal; vol. 21; nb. 7; (2015); p. 2954 - 2960, View in Reaxys

3h

Deshidi, Ramesh; Devari, Shekaraiah; Shah, Bhahwal Ali; European Journal of Organic Chemistry; vol. 2015; nb. 7; (2015); p. 1428 - 1432, View in Reaxys

3r

Fan, Weizheng; Shi, Dongyang; Feng, Bainian; Tetrahedron Letters; vol. 56; nb. 31; (2015); p. 4638 - 4641, View in Reaxys

1j

Mamillapalli, N. Chary; Sekar, Govindasamy; Advanced Synthesis and Catalysis; vol. 357; nb. 14-15; (2015); p. 3273 - 3283, View in Reaxys

12

Wedler, Henry B.; Palazzo, Teresa A.; Pemberton, Ryan P.; Hamann, Christian S.; Kurth, Mark J.; Tantillo, Dean J.; Bioorganic and Medicinal Chemistry Letters; vol. 25; nb. 19; (2015); p. 4153 - 4157, View in Reaxys

1

Johansson et al.; Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry; vol. 30; (1976); p.

383,387, View in Reaxys; Chen, Bingfeng; Li, Fengbo; Huang, Zhijun; Lu, Tao; Yuan, Guoqing; Applied Catalysis A: General; vol. 481; (2014); p. 54 - 63, View in Reaxys

3v

Zhang, Zhenlei; Su, Jihu; Zha, Zhenggen; Wang, Zhiyong; Chemical Communications; vol. 49; nb. 79; (2013); p.

8982 - 8984, View in Reaxys; Zhou, Mingxin; Song, Qiuling; Synthesis (Germany); vol. 46; nb. 14; (2014); p. 1853 1858; Art.No: SS-2014-C0127-ST, View in Reaxys

3k

Mupparapu, Nagaraju; Khan, Shahnawaz; Battula, Satyanarayana; Kushwaha, Manoj; Gupta, Ajai Prakash; Ahmed, Qazi Naveed; Vishwakarma, Ram A.; Organic Letters; vol. 16; nb. 4; (2014); p. 1152 - 1155, View in Reaxys

3ba

Deshidi, Ramesh; Kumar, Manjeet; Devari, Shekaraiah; Shah, Bhahwal Ali; Chemical Communications; vol. 50; nb. 67; (2014); p. 9533 - 9535, View in Reaxys

1i

Mamillapalli, N. Chary; Sekar, Govindasamy; RSC Advances; vol. 4; nb. 105; (2014); p. 61077 - 61085, View in Reaxys

3f;2f

Kotha, Surya Srinivas; Chandrasekar, Selvaraj; Sahu, Samrat; Sekar, Govindasamy; European Journal of Organic Chemistry; vol. 2014; nb. 33; (2014); p. 7451 - 7457, View in Reaxys

2c

Liu, Le; Du, Liang; Zhang-Negrerie, Daisy; Du, Yunfei; Zhao, Kang; Organic Letters; vol. 16; nb. 21; (2014); p.

5772 - 5775, View in Reaxys

3ag

Zhang, Chunyan; Liu, Jianhua; Xia, Chungu; Organic and Biomolecular Chemistry; vol. 12; nb. 47; (2014); p. 9702 9706, View in Reaxys

6b

Chen, Wen-Lin; Li, Ji-Hui; Meng, Xu; Tang, Dong; Guo, Shuai-Bo; Chen, Bao-Hua; Tetrahedron Letters; vol. 54; nb. 4; (2013); p. 295 - 299, View in Reaxys

3l

Zhang, Xiaobin; Wang, Min; Zhang, Yicheng; Wang, Lei; RSC Advances; vol. 3; nb. 5; (2013); p. 1311 - 1316, View in Reaxys

3ad

Li, Dengke; Wang, Min; Liu, Jie; Zhao, Qiong; Wang, Lei; Chemical Communications; vol. 49; nb. 35; (2013); p.

3640 - 3642, View in Reaxys

4d

Zhang, Xiaobin; Yang, Wenchao; Wang, Lei; Organic and Biomolecular Chemistry; vol. 11; nb. 22; (2013); p. 3649 3654, View in Reaxys

4b

Wang, Hua; Guo, Li-Na; Duan, Xin-Hua; Organic and Biomolecular Chemistry; vol. 11; nb. 28; (2013); p. 4573 4576, View in Reaxys

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5aa

Zhang, Jian; Liu, Yu; Chiba, Shunsuke; Loh, Teck-Peng; Chemical Communications; vol. 49; nb. 97; (2013); p.

11439 - 11441, View in Reaxys

3bc

Mai, Wen-Peng; Wang, Hui-Hui; Li, Zhi-Cheng; Yuan, Jin-Wei; Xiao, Yong-Mei; Yang, Liang-Ru; Mao, Pu; Qu, Ling-Bo; Chemical Communications; vol. 48; nb. 81; (2012); p. 10117 - 10119, View in Reaxys

7c

Wei, Wei; Shao, Ying; Hu, Huayou; Zhang, Feng; Zhang, Chao; Xu, Yuan; Wan, Xiaobing; Journal of Organic Chemistry; vol. 77; nb. 17; (2012); p. 7157 - 7165, View in Reaxys

19

Moehrle; Rohn; Westle; Pharmazie; vol. 61; nb. 5; (2006); p. 391 - 399, View in Reaxys

XXI

Khlebnikov; Novikov; Kusei; Kopf; Kostikov; Russian Journal of Organic Chemistry; vol. 39; nb. 4; (2003); p. 559 573, View in Reaxys

Tab.5; entry 5

Tsukada, Naofumi; Ohba, Yoichi; Inoue, Yoshio; Journal of Organometallic Chemistry; vol. 687; nb. 2; (2003); p. 436 - 443, View in Reaxys

3f

Zhou, Tao; Chen, Zhen-Chu; Journal of Chemical Research - Part S; nb. 3; (2001); p. 116 - 117, View in Reaxys

α-ketoamide from 4

Axten, Jeffrey M.; Krim, Lori; Kung, Hank F.; Winkler, Jeffrey D.; Journal of Organic Chemistry; vol. 63; nb. 26; (1998); p. 9628 - 9629, View in Reaxys

13a

Toda, Fumio; Miyamoto, Hisakazu; Matsukawa, Rikiya; Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999); nb. 12; (1992); p. 1461 - 1462, View in Reaxys

2a;R1=Ph,R2,R3=(CH2)5-

Murata, Satoru; Suzuki, Kaoru; Miura, Masahiro; Nomura, Masakatsu; Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999); nb. 2; (1990); p. 361 - 365, View in Reaxys

8b

Toda, Fumio; Tanaka, Koichi; Tange, Hiroshi; Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999); (1989); p. 1555 - 1556, View in Reaxys

5a X=CH2 / i (VIII) Kaftory, Menahem; Tetrahedron; vol. 43; nb. 7; (1987); p. 1503 - 1512, View in Reaxys 17

Imai, Nobuyuki; Achiwa, Kazuo; Chemical and Pharmaceutical Bulletin; vol. 35; nb. 7; (1987); p. 2646 - 2655, View in Reaxys

PhCOCON(CH2)5

Ozawa, Fumiyuki; Soyama, Hidehiko; Yanagihara, Hisayoshi; Aoyama, Issei; Takino, Hiroaki; et al.; Journal of the American Chemical Society; vol. 107; nb. 11; (1985); p. 3235 - 3245, View in Reaxys

Table 1 Entry 4 Col. 5

Ozawa, Fumiyuki; Soyama, Hidehiko; Yamamoto, Takakazu; Yamamoto, Akio; Tetrahedron Letters; vol. 23; nb.

33; (1982); p. 3383 - 3386, View in Reaxys

1d

Aoyama et al.; Journal of the American Chemical Society; vol. 101; (1979); p. 5343,5344, View in Reaxys

Id

Glushkov et al.; Zhurnal Organicheskoi Khimii; vol. 10; (1974); p. 304,304,306, View in Reaxys

V

Earle et al.; Journal of the Chemical Society [Section] C: Organic; (1969); p. 2093,2096, View in Reaxys

Druglikeness (1) 1 of 1

LogP

2.047

H Bond Donors

0

H Bond Acceptors

3

Rotatable Bonds

3

TPSA

37.38

Lipinski Number

4

Veber Number

2

Derivative (1) Comment (Derivative) 2,4-Dinitrophenylhydrazon: F= 217.5-218.5grad

References Glushkov et al.; Zhurnal Organicheskoi Khimii; vol. 10; (1974); p. 304,304,306, View in Reaxys

Melting Point (20) 1 of 20

Melting Point [°C]

104.7 - 106.3

Location

Paragraph 0048

Patent; UNIVERSITÉ DE LIÈGE; MONBALIU, Jean-Christophe; GERARDY, Romaric; (30 pag.); WO2018/50546; (2018); (A1) English, View in Reaxys 2 of 20

Melting Point [°C]

104 - 105

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Nekkanti, Shalini; Veeramani, Karuna; Praveen Kumar, Niggula; Shankaraiah, Nagula; Green Chemistry; vol. 18; nb. 11; (2016); p. 3439 - 3447, View in Reaxys 3 of 20

Melting Point [°C]

94 - 96

Location

supporting information

Liu, Chengkou; Yang, Zhao; Guo, Shiyu; Zeng, Yu; Zhu, Ning; Li, Xin; Fang, Zheng; Guo, Kai; Organic and Biomolecular Chemistry; vol. 14; nb. 36; (2016); p. 8570 - 8575, View in Reaxys 4 of 20

Melting Point [°C]

94 - 95

Ramanathan, Mani; Kuo, Chun-Kai; Liu, Shiuh-Tzung; Organic and Biomolecular Chemistry; vol. 14; nb. 48; (2016); p.

11446 - 11453, View in Reaxys 5 of 20

Melting Point [°C]

90 - 92

Sharma, Nidhi; Kotha, Surya Srinivas; Lahiri, Nabajit; Sekar, Govindasamy; Synthesis (Germany); vol. 47; nb. 5; (2015); p. 726 - 736; Art.No: SS-2014-T0695-OP, View in Reaxys 6 of 20

Melting Point [°C]

101.1 - 101.6

Location

supporting information

Wedler, Henry B.; Palazzo, Teresa A.; Pemberton, Ryan P.; Hamann, Christian S.; Kurth, Mark J.; Tantillo, Dean J.; Bioorganic and Medicinal Chemistry Letters; vol. 25; nb. 19; (2015); p. 4153 - 4157, View in Reaxys 7 of 20

Melting Point [°C]

95 - 97

Location

supporting information

Kotha, Surya Srinivas; Sekar, Govindasamy; Tetrahedron Letters; vol. 56; nb. 46; (2015); p. 6323 - 6326, View in Reaxys 8 of 20

Melting Point [°C]

94 - 96

Kotha, Surya Srinivas; Chandrasekar, Selvaraj; Sahu, Samrat; Sekar, Govindasamy; European Journal of Organic Chemistry; vol. 2014; nb. 33; (2014); p. 7451 - 7457, View in Reaxys 9 of 20

Melting Point [°C]

56 - 58

Location

supporting information

Chen, Wen-Lin; Li, Ji-Hui; Meng, Xu; Tang, Dong; Guo, Shuai-Bo; Chen, Bao-Hua; Tetrahedron Letters; vol. 54; nb. 4; (2013); p. 295 - 299, View in Reaxys 10 of 20

Melting Point [°C]

102 - 104

Location

supporting information

Wang, Hua; Guo, Li-Na; Duan, Xin-Hua; Organic and Biomolecular Chemistry; vol. 11; nb. 28; (2013); p. 4573 - 4576, View in Reaxys 11 of 20

Melting Point [°C]

106 - 108

Location

supporting information

Lamani, Manjunath; Prabhu, Kandikere Ramaiah; Chemistry - A European Journal; vol. 18; nb. 46; (2012); p. 14638 14642, View in Reaxys 12 of 20

Melting Point [°C]

109 - 111

Zhang, Juan; Wei, Ying; Lin, Shaoxia; Liang, Fushun; Liu, Pengjun; Organic and Biomolecular Chemistry; vol. 10; nb. 46; (2012); p. 9237 - 9242, View in Reaxys 13 of 20

Melting Point [°C]

104 - 106

Shanmugapriya; Shankar; Satyanarayana; Dahanukar, Vilas H.; Kumar, U. K. Syam; Vembu; Synlett; nb. 19; (2008); p.

2945 - 2950, View in Reaxys 14 of 20

Melting Point [°C]

104 - 105

Song, Bingrui; Wang, Siyuan; Sun, Caiyun; Deng, Hongmei; Xu, Bin; Tetrahedron Letters; vol. 48; nb. 51; (2007); p. 8982 8986, View in Reaxys 15 of 20

Melting Point [°C]

99 - 101

Solvent (Melting Point)

diethyl ether

Khlebnikov; Novikov; Kusei; Kopf; Kostikov; Russian Journal of Organic Chemistry; vol. 39; nb. 4; (2003); p. 559 - 573, View in Reaxys

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16 of 20

Melting Point [°C]

107 - 108

Solvent (Melting Point)

hexane

Earle et al.; Journal of the Chemical Society [Section] C: Organic; (1969); p. 2093,2096, View in Reaxys; Imai, Nobuyuki; Achiwa, Kazuo; Chemical and Pharmaceutical Bulletin; vol. 35; nb. 7; (1987); p. 2646 - 2655, View in Reaxys 17 of 20

Melting Point [°C]

106

Aoyama et al.; Journal of the American Chemical Society; vol. 101; (1979); p. 5343,5344, View in Reaxys 18 of 20

Melting Point [°C]

107 - 108

Johansson et al.; Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry; vol. 30; (1976); p. 383,387, View in Reaxys 19 of 20

Melting Point [°C]

104 - 106

Glushkov et al.; Zhurnal Organicheskoi Khimii; vol. 10; (1974); p. 304,304,306, View in Reaxys 20 of 20

Melting Point [°C]

104.5 - 105.5

Muchowski,J.M.; Tetrahedron Letters; (1966); p. 1773 - 1778, View in Reaxys Density (1) 1 of 1

Density [g·cm-3]

1.234

Type (Density)

crystallographic

Kaftory, Menahem; Tetrahedron; vol. 43; nb. 7; (1987); p. 1503 - 1512, View in Reaxys Chromatographic Data (2) Chromatographic Location data TLC (Thin layer chromatography)

supporting informa- Lamani, Manjunath; Prabhu, Kandikere Ramaiah; Chemistry - A European Journal; vol. 18; tion nb. 46; (2012); p. 14638 - 14642, View in Reaxys; Wang, Hua; Guo, Li-Na; Duan, Xin-Hua; Organic and Biomolecular Chemistry; vol. 11; nb. 28; (2013); p. 4573 - 4576, View in Reaxys; Kotha, Surya Srinivas; Sekar, Govindasamy; Tetrahedron Letters; vol. 56; nb. 46; (2015); p.

6323 - 6326, View in Reaxys

TLC (Thin layer chromatography)

Crystal Phase (1) Description (Crystal Phase) Crystal structure determination

Sharma, Nidhi; Kotha, Surya Srinivas; Lahiri, Nabajit; Sekar, Govindasamy; Synthesis (Germany); vol. 47; nb. 5; (2015); p. 726 - 736; Art.No: SS-2014-T0695-OP, View in Reaxys; Kotha, Surya Srinivas; Chandrasekar, Selvaraj; Sahu, Samrat; Sekar, Govindasamy; European Journal of Organic Chemistry; vol. 2014; nb. 33; (2014); p. 7451 - 7457, View in Reaxys Comment (Crystal Phase)

References

α=103.1 grad, Kaftory, Menahem; Tetrahedron; vol. 43; nb. 7; (1987); p. 1503 - 1512, View in Reaxys a=9.58 Angstroem, b=11.4 Angstroem, c=10.99 Angstroem, n=4.; Method of determination: X-ray Diffraction

Crystal Property Description (10) Colour & Other Location Properties yellow

References

References Wei, Wei; Shao, Ying; Hu, Huayou; Zhang, Feng; Zhang, Chao; Xu, Yuan; Wan, Xiaobing; Journal of Organic Chemistry; vol. 77; nb. 17; (2012); p. 7157 - 7165, View in Reaxys; Zhao, Qiong; Miao, Tao; Zhang, Xiaobin; Zhou, Wei; Wang, Lei; Organic and Biomolecular Chemistry; vol. 11; nb. 11; (2013); p. 1867 - 1873, View in Reaxys; Zhang, Xiaobin; Yang, Wenchao; Wang, Lei; Organic and Biomolecular Chemistry; vol. 11; nb. 22; (2013); p. 3649 - 3654, View in Reaxys; Zhou, Mingxin; Song, Qiuling; Synthesis (Germany); vol. 46; nb. 14; (2014); p.

1853 - 1858; Art.No: SS-2014-C0127-ST, View in Reaxys; Sharma, Nidhi; Kotha, Surya Srinivas; Lahiri, Nabajit; Sekar, Govindasamy; Synthesis (Germany); vol. 47; nb. 5; (2015); p. 726 736; Art.No: SS-2014-T0695-OP, View in Reaxys; Kotha, Surya Srinivas; Chandrasekar, Selvaraj; Sahu, Samrat; Sekar, Govindasamy; European Journal of Organic Chemistry; vol. 2014; nb. 33; (2014); p. 7451 - 7457, View in Reaxys; Zhang, Xueyao; Yang, Honglei; Huo, Yong; Li, Jing; Ma, Jianxin; Ma, Jiantai; Dalton Transactions; vol. 45; nb. 21; (2016); p. 8972 - 8983, View in Reaxys; Nekkanti, Shalini; Veeramani, Karuna; Praveen Kumar, Niggula; Shankaraiah, Nagula; Green Chemistry; vol. 18; nb. 11; (2016); p. 3439 - 3447, View in Reaxys; Wang,

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2018-08-10 16:34:57

Dan; Zhang, Kuan; Jia, Luhan; Zhang, Danting; Zhang, Yue; Cheng, Yujia; Lin, Chang; Wang, Bo; Organic and Biomolecular Chemistry; vol. 15; nb. 16; (2017); p. 3427 - 3434, View in Reaxys; Dutta, Pratip Kumar; Dhar, Basabbijayi; Sen, Subhabrata; New Journal of Chemistry; vol. 42; nb. 14; (2018); p. 12062 - 12071, View in Reaxys white

Paragraph 0047

Patent; UNIVERSITÉ DE LIÈGE; MONBALIU, Jean-Christophe; GERARDY, Romaric; (30 pag.); WO2018/50546; (2018); (A1) English, View in Reaxys

colourless

Page/Page column 22

Patent; COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH; SUDALAI, Arumugam; PRASAD, Pragati Kishore; REDDI, Rambabu; (31 pag.); WO2017/77550; (2017); (A1) English, View in Reaxys

white

Paragraph 0065

Patent; Hefei Lifeon Pharmaceutical Co., Ltd.; Pei, Lin; Li, Bing; Hu, Dejin; Chen, Jun; Gao, Meihua; Ji, Junqiu; (11 pag.); CN106349151; (2017); (A) Chinese, View in Reaxys

colourless

supporting informa- Mai, Wen-Peng; Wang, Hui-Hui; Li, Zhi-Cheng; Yuan, Jin-Wei; Xiao, Yong-Mei; Yang, tion Liang-Ru; Mao, Pu; Qu, Ling-Bo; Chemical Communications; vol. 48; nb. 81; (2012); p. 10117 - 10119, View in Reaxys; Prasad, Pragati K.; Reddi, Rambabu N.; Sudalai, Arumugam; Organic Letters; vol. 18; nb. 3; (2016); p. 500 - 503, View in Reaxys

yellow

supporting informa- Lamani, Manjunath; Prabhu, Kandikere Ramaiah; Chemistry - A European Journal; vol. 18; tion nb. 46; (2012); p. 14638 - 14642, View in Reaxys; Chen, Wen-Lin; Li, Ji-Hui; Meng, Xu; Tang, Dong; Guo, Shuai-Bo; Chen, Bao-Hua; Tetrahedron Letters; vol. 54; nb. 4; (2013); p. 295 - 299, View in Reaxys; Li, Dengke; Wang, Min; Liu, Jie; Zhao, Qiong; Wang, Lei; Chemical Communications; vol. 49; nb. 35; (2013); p. 3640 - 3642, View in Reaxys; Wang, Hua; Guo, Li-Na; Duan, Xin-Hua; Organic and Biomolecular Chemistry; vol. 11; nb. 28; (2013); p. 4573 - 4576, View in Reaxys; Mupparapu, Nagaraju; Khan, Shahnawaz; Battula, Satyanarayana; Kushwaha, Manoj; Gupta, Ajai Prakash; Ahmed, Qazi Naveed; Vishwakarma, Ram A.; Organic Letters; vol. 16; nb. 4; (2014); p. 1152 - 1155, View in Reaxys; Du, Bingnan; Jin, Bo; Sun, Peipei; Organic and Biomolecular Chemistry; vol. 12; nb. 26; (2014); p. 4586 - 4589, View in Reaxys; Mupparapu, Nagaraju; Battini, Narsaiah; Battula, Satyanarayana; Khan, Shahnawaz; Vishwakarma, Ram A.; Ahmed, Qazi Naveed; Chemistry - A European Journal; vol. 21; nb. 7; (2015); p. 2954 - 2960, View in Reaxys; Zhang, Chunyan; Liu, Jianhua; Xia, Chungu; Organic and Biomolecular Chemistry; vol. 12; nb. 47; (2014); p. 9702 - 9706, View in Reaxys; Liu, Le; Du, Liang; Zhang-Negrerie, Daisy; Du, Yunfei; Zhao, Kang; Organic Letters; vol. 16; nb. 21; (2014); p. 5772 - 5775, View in Reaxys; Kotha, Surya Srinivas; Sekar, Govindasamy; Tetrahedron Letters; vol. 56; nb. 46; (2015); p. 6323 - 6326, View in Reaxys; Liu, Chengkou; Yang, Zhao; Guo, Shiyu; Zeng, Yu; Zhu, Ning; Li, Xin; Fang, Zheng; Guo, Kai; Organic and Biomolecular Chemistry; vol. 14; nb. 36; (2016); p. 8570 - 8575, View in Reaxys; Yu, Lu; Somfai, Peter; Synlett; vol. 27; nb. 18; (2016); p. 2587 - 2590; Art.No: ST-2016-B0315L, View in Reaxys

white

Zhang, Juan; Wei, Ying; Lin, Shaoxia; Liang, Fushun; Liu, Pengjun; Organic and Biomolecular Chemistry; vol. 10; nb. 46; (2012); p. 9237 - 9242, View in Reaxys; Ramanathan, Mani; Kuo, Chun-Kai; Liu, Shiuh-Tzung; Organic and Biomolecular Chemistry; vol. 14; nb. 48; (2016); p. 11446 - 11453, View in Reaxys

beige

supporting informa- Wedler, Henry B.; Palazzo, Teresa A.; Pemberton, Ryan P.; Hamann, Christian S.; Kurth, tion Mark J.; Tantillo, Dean J.; Bioorganic and Medicinal Chemistry Letters; vol. 25; nb. 19; (2015); p. 4153 - 4157, View in Reaxys

yellow

supporting informa- Zhang, Chun; Zong, Xiaolin; Zhang, Liangren; Jiao, Ning; Organic Letters; vol. 14; nb. 13; tion (2012); p. 3280 - 3283, View in Reaxys; Zhang, Xiaobin; Wang, Lei; Green Chemistry; vol. 14; nb. 8; (2012); p. 2141 - 2145, View in Reaxys

light-yellow

Song, Bingrui; Wang, Siyuan; Sun, Caiyun; Deng, Hongmei; Xu, Bin; Tetrahedron Letters; vol. 48; nb. 51; (2007); p. 8982 - 8986, View in Reaxys

Crystal System (1) Crystal System References monoclinic

Kaftory, Menahem; Tetrahedron; vol. 43; nb. 7; (1987); p. 1503 - 1512, View in Reaxys

Space Group (1) Space Group

References

14

Kaftory, Menahem; Tetrahedron; vol. 43; nb. 7; (1987); p. 1503 - 1512, View in Reaxys

NMR Spectroscopy (49) 1 of 49

Description (NMR Spectroscopy)

Chemical shifts; Spectrum

Nucleus (NMR Spectroscopy)

1H

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Solvents (NMR Spectroscopy)

chloroform-d1

Frequency (NMR Spectro- 400 scopy) [MHz] Location

supporting information

Zhang, Xiaobin; Wang, Lei; Green Chemistry; vol. 14; nb. 8; (2012); p. 2141 - 2145, View in Reaxys; Mai, Wen-Peng; Wang, Hui-Hui; Li, Zhi-Cheng; Yuan, Jin-Wei; Xiao, Yong-Mei; Yang, Liang-Ru; Mao, Pu; Qu, Ling-Bo; Chemical Communications; vol. 48; nb. 81; (2012); p. 10117 - 10119, View in Reaxys; Lamani, Manjunath; Prabhu, Kandikere Ramaiah; Chemistry - A European Journal; vol. 18; nb. 46; (2012); p. 14638 - 14642, View in Reaxys; Zhao, Qiong; Miao, Tao; Zhang, Xiaobin; Zhou, Wei; Wang, Lei; Organic and Biomolecular Chemistry; vol. 11; nb. 11; (2013); p. 1867 - 1873, View in Reaxys; Li, Dengke; Wang, Min; Liu, Jie; Zhao, Qiong; Wang, Lei; Chemical Communications; vol. 49; nb. 35; (2013); p. 3640 - 3642, View in Reaxys; Zhang, Xiaobin; Yang, Wenchao; Wang, Lei; Organic and Biomolecular Chemistry; vol. 11; nb. 22; (2013); p. 3649 - 3654, View in Reaxys; Zhang, Zhenlei; Su, Jihu; Zha, Zhenggen; Wang, Zhiyong; Chemical Communications; vol.

49; nb. 79; (2013); p. 8982 - 8984, View in Reaxys; Mupparapu, Nagaraju; Khan, Shahnawaz; Battula, Satyanarayana; Kushwaha, Manoj; Gupta, Ajai Prakash; Ahmed, Qazi Naveed; Vishwakarma, Ram A.; Organic Letters; vol. 16; nb. 4; (2014); p. 1152 - 1155, View in Reaxys; Du, Bingnan; Jin, Bo; Sun, Peipei; Organic and Biomolecular Chemistry; vol. 12; nb.

26; (2014); p. 4586 - 4589, View in Reaxys; Zhou, Mingxin; Song, Qiuling; Synthesis (Germany); vol. 46; nb. 14; (2014); p.

1853 - 1858; Art.No: SS-2014-C0127-ST, View in Reaxys; Mupparapu, Nagaraju; Battini, Narsaiah; Battula, Satyanarayana; Khan, Shahnawaz; Vishwakarma, Ram A.; Ahmed, Qazi Naveed; Chemistry - A European Journal; vol. 21; nb. 7; (2015); p. 2954 - 2960, View in Reaxys; Zhang, Chunyan; Liu, Jianhua; Xia, Chungu; Organic and Biomolecular Chemistry; vol. 12; nb. 47; (2014); p. 9702 - 9706, View in Reaxys; Deshidi, Ramesh; Devari, Shekaraiah; Shah, Bhahwal Ali; European Journal of Organic Chemistry; vol. 2015; nb. 7; (2015); p. 1428 - 1432, View in Reaxys; Sharma, Nidhi; Kotha, Surya Srinivas; Lahiri, Nabajit; Sekar, Govindasamy; Synthesis (Germany); vol. 47; nb. 5; (2015); p. 726 - 736; Art.No: SS-2014T0695-OP, View in Reaxys; Kotha, Surya Srinivas; Sekar, Govindasamy; Tetrahedron Letters; vol. 56; nb. 46; (2015); p. 6323 - 6326, View in Reaxys; Meena, Samdarshi; Singh, Rohit; Vishwakarma, Ram A.; Aga, Mushtaq A.; Jain, Shreyans K.; Tetrahedron Letters; vol. 57; nb. 33; (2016); p. 3715 - 3717, View in Reaxys; Liu, Chengkou; Yang, Zhao; Guo, Shiyu; Zeng, Yu; Zhu, Ning; Li, Xin; Fang, Zheng; Guo, Kai; Organic and Biomolecular Chemistry; vol. 14; nb. 36; (2016); p. 8570 8575, View in Reaxys; Yu, Lu; Somfai, Peter; Synlett; vol. 27; nb. 18; (2016); p. 2587 - 2590; Art.No: ST-2016-B0315-L, View in Reaxys; Ramanathan, Mani; Kuo, Chun-Kai; Liu, Shiuh-Tzung; Organic and Biomolecular Chemistry; vol. 14; nb.

48; (2016); p. 11446 - 11453, View in Reaxys; Wang, Dan; Zhang, Kuan; Jia, Luhan; Zhang, Danting; Zhang, Yue; Cheng, Yujia; Lin, Chang; Wang, Bo; Organic and Biomolecular Chemistry; vol. 15; nb. 16; (2017); p. 3427 - 3434, View in Reaxys; Dutta, Pratip Kumar; Dhar, Basabbijayi; Sen, Subhabrata; New Journal of Chemistry; vol. 42; nb. 14; (2018); p. 12062 12071, View in Reaxys 2 of 49

Description (NMR Spectroscopy)

Chemical shifts; Spectrum

Nucleus (NMR Spectroscopy)

13C

Solvents (NMR Spectroscopy)

chloroform-d1

Frequency (NMR Spectro- 100 scopy) [MHz] Location

supporting information

Zhang, Xiaobin; Wang, Lei; Green Chemistry; vol. 14; nb. 8; (2012); p. 2141 - 2145, View in Reaxys; Mai, Wen-Peng; Wang, Hui-Hui; Li, Zhi-Cheng; Yuan, Jin-Wei; Xiao, Yong-Mei; Yang, Liang-Ru; Mao, Pu; Qu, Ling-Bo; Chemical Communications; vol. 48; nb. 81; (2012); p. 10117 - 10119, View in Reaxys; Lamani, Manjunath; Prabhu, Kandikere Ramaiah; Chemistry - A European Journal; vol. 18; nb. 46; (2012); p. 14638 - 14642, View in Reaxys; Zhao, Qiong; Miao, Tao; Zhang, Xiaobin; Zhou, Wei; Wang, Lei; Organic and Biomolecular Chemistry; vol. 11; nb. 11; (2013); p. 1867 - 1873, View in Reaxys; Li, Dengke; Wang, Min; Liu, Jie; Zhao, Qiong; Wang, Lei; Chemical Communications; vol. 49; nb. 35; (2013); p. 3640 - 3642, View in Reaxys; Zhang, Xiaobin; Yang, Wenchao; Wang, Lei; Organic and Biomolecular Chemistry; vol. 11; nb. 22; (2013); p. 3649 - 3654, View in Reaxys; Wang, Hua; Guo, Li-Na; Duan, Xin-Hua; Organic and Biomolecular Chemistry; vol. 11; nb.

28; (2013); p. 4573 - 4576, View in Reaxys; Zhang, Zhenlei; Su, Jihu; Zha, Zhenggen; Wang, Zhiyong; Chemical Communications; vol. 49; nb. 79; (2013); p. 8982 - 8984, View in Reaxys; Du, Bingnan; Jin, Bo; Sun, Peipei; Organic and Biomolecular Chemistry; vol. 12; nb. 26; (2014); p. 4586 - 4589, View in Reaxys; Deshidi, Ramesh; Kumar, Manjeet; Devari, Shekaraiah; Shah, Bhahwal Ali; Chemical Communications; vol. 50; nb. 67; (2014); p. 9533 - 9535, View in Reaxys; Zhang, Chunyan; Liu, Jianhua; Xia, Chungu; Organic and Biomolecular Chemistry; vol. 12; nb. 47; (2014); p. 9702 - 9706, View in Reaxys; Sharma, Nidhi; Kotha, Surya Srinivas; Lahiri, Nabajit; Sekar, Govindasamy; Synthesis (Germany); vol. 47; nb. 5; (2015); p. 726 - 736; Art.No: SS-2014-T0695-OP, View in Reaxys; Kotha, Surya Srinivas; Sekar, Govindasamy; Tetrahedron Letters; vol. 56; nb. 46; (2015); p. 6323 - 6326, View in Reaxys; Meena, Samdarshi; Singh, Rohit; Vishwakarma, Ram A.; Aga, Mushtaq A.; Jain, Shreyans K.; Tetrahedron Letters; vol. 57; nb. 33; (2016); p. 3715 - 3717, View in Reaxys; Yu, Lu; Somfai, Peter; Synlett; vol. 27; nb. 18; (2016); p. 2587 - 2590; Art.No: ST-2016-B0315-L, View in Reaxys; Ramanathan, Mani; Kuo, Chun-Kai; Liu, Shiuh-Tzung; Organic and Biomolecular Chemistry; vol. 14; nb. 48; (2016); p. 11446 - 11453, View in Reaxys; Wang, Dan; Zhang, Kuan; Jia, Luhan; Zhang, Danting; Zhang, Yue; Cheng, Yujia; Lin, Chang; Wang,

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Bo; Organic and Biomolecular Chemistry; vol. 15; nb. 16; (2017); p. 3427 - 3434, View in Reaxys; Dutta, Pratip Kumar; Dhar, Basabbijayi; Sen, Subhabrata; New Journal of Chemistry; vol. 42; nb. 14; (2018); p. 12062 - 12071, View in Reaxys 3 of 49

Description (NMR Spectroscopy)

Chemical shifts

Nucleus (NMR Spectroscopy)

1H

Solvents (NMR Spectroscopy)

chloroform-d1

Original Text (NMR Spec- 1H NMR (α, CDCl3): 7.90-7.93 (, 2H); 7.59-7.63 (m, 1H); 7.44-7.51 (m, 2H); 3.66-3.70 (m, 2H); troscopy) 3.24-3.28 (m, 2H); 1.64-1.69 (m, 4H); 1.48-1.55 (m, 2H) Signals [ppm]

7.9 - 7.93; 7.59 - 7.63; 7.44 - 7.51; 3.66 - 3.7; 3.24 - 3.28; 1.64 - 1.69; 1.48 - 1.55

Kind of signal

2H; m, 1H; m, 2H; m, 2H; m, 2H; m, 4H; m, 2H

Urbán, Béla; Szabó, Péter; Srankó, Dávid; Sáfrán, György; Kollár, László; Skoda-Földes, Rita; Molecular Catalysis; vol.

445; (2018); p. 195 - 205, View in Reaxys 4 of 49

Description (NMR Spectroscopy)

Chemical shifts

Nucleus (NMR Spectroscopy)

13C

Solvents (NMR Spectroscopy)

chloroform-d1

Original Text (NMR Spectroscopy)

13C

Signals [ppm]

191.9; 165.4; 134.5; 133.2; 129.4; 128.9; 46.9; 42; 26.1; 25.4; 24.3

NMR (α, CDCl3): 191.9; 165.4; 134.5; 133.2; 129.4; 128.9; 46.9; 42.0; 26.1; 25.4; 24.3

Urbán, Béla; Szabó, Péter; Srankó, Dávid; Sáfrán, György; Kollár, László; Skoda-Földes, Rita; Molecular Catalysis; vol.

445; (2018); p. 195 - 205, View in Reaxys 5 of 49

Description (NMR Spectroscopy)

Chemical shifts

Nucleus (NMR Spectroscopy)

1H

Solvents (NMR Spectroscopy)

chloroform-d1

Frequency (NMR Spectro- 400 scopy) [MHz] Original Text (NMR Spec- 1H NMR (CDCI3, 400 MHz): 6 = 7.92-7.98 (m, 2H), 7.61-7.67 (m, 1H), 7.51 3, 2H, i = 7.7 Hz), troscopy) 3.66-3.75 (m, 2H),3.25-3.33 (m, 2H), 1.66-1.74 (m, 4H), 1.52-1.56 (m, 2H) ppm; “C NMR (CDCI3, 100.6 MHz): 6 = 191.9, 165.4, 134.6,133.2, 129.5, 129.0, 47.0, 42.1, 26.1, 25.4, 24.3 ppm Location

Paragraph 0048

Patent; UNIVERSITÉ DE LIÈGE; MONBALIU, Jean-Christophe; GERARDY, Romaric; (30 pag.); WO2018/50546; (2018); (A1) English, View in Reaxys 6 of 49

Description (NMR Spectroscopy)

Chemical shifts

Nucleus (NMR Spectroscopy)

13C

Solvents (NMR Spectroscopy)

chloroform-d1

Frequency (NMR Spectro- 100.6 scopy) [MHz] Original Text (NMR Spec- 1C NMR (CDCI3, 100.6 MHz): 6 = 191.9, 165.4, 134.6,133.2, 129.5, 129.0, 47.0, 42.1, 26.1, 25.4, troscopy) 24.3 ppm Location

Paragraph 0048

Patent; UNIVERSITÉ DE LIÈGE; MONBALIU, Jean-Christophe; GERARDY, Romaric; (30 pag.); WO2018/50546; (2018); (A1) English, View in Reaxys

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7 of 49

Description (NMR Spectroscopy)

Chemical shifts

Nucleus (NMR Spectroscopy)

1H

Solvents (NMR Spectroscopy)

chloroform-d1

Frequency (NMR Spectro- 200 scopy) [MHz] Original Text (NMR Spec- IH NMR (200 MHz, CDC13): α 1.47-1.62 (m, 2H) 1.65- 1.74 (m, 5H) 3.25-3.35 (m, 2H) 3.65-3.78 troscopy) (m, 2H) 7.45- 7.57 (m, 2H) 7.60-7.70 (m, IH) 7.89-8.01 (m, 2H); Location

Page/Page column 22

Patent; COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH; SUDALAI, Arumugam; PRASAD, Pragati Kishore; REDDI, Rambabu; (31 pag.); WO2017/77550; (2017); (A1) English, View in Reaxys 8 of 49

Description (NMR Spectroscopy)

Chemical shifts

Nucleus (NMR Spectroscopy)

13C

Solvents (NMR Spectroscopy)

chloroform-d1

Frequency (NMR Spectro- 50 scopy) [MHz] Original Text (NMR Spec- 13C NMR (50 MHz, CDC13): α 24.2, 25.3, 26.1, 42.0, 46.9, 128.9, 129.4, 133.1, 134.5, 165.3, troscopy) 191.8; Location

Page/Page column 22

Patent; COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH; SUDALAI, Arumugam; PRASAD, Pragati Kishore; REDDI, Rambabu; (31 pag.); WO2017/77550; (2017); (A1) English, View in Reaxys 9 of 49

Description (NMR Spectroscopy)

Chemical shifts

Nucleus (NMR Spectroscopy)

1H

Solvents (NMR Spectroscopy)

chloroform-d1

Frequency (NMR Spectro- 400 scopy) [MHz] Location

supporting information

Zhang, Jian; Liu, Yu; Chiba, Shunsuke; Loh, Teck-Peng; Chemical Communications; vol. 49; nb. 97; (2013); p. 11439 11441, View in Reaxys; Liu, Xing-Xing; Wu, Zhao-Yang; He, Yong-Qin; Zhou, Xiao-Qiang; Hu, Ting; Ma, Chao-Wei; Huang, Guo-Sheng; Advanced Synthesis and Catalysis; vol. 358; nb. 15; (2016); p. 2385 - 2391, View in Reaxys 10 of 49

Description (NMR Spectroscopy)

Chemical shifts

Nucleus (NMR Spectroscopy)

13C

Solvents (NMR Spectroscopy)

chloroform-d1

Frequency (NMR Spectro- 100 scopy) [MHz] Location

supporting information

Zhang, Jian; Liu, Yu; Chiba, Shunsuke; Loh, Teck-Peng; Chemical Communications; vol. 49; nb. 97; (2013); p. 11439 11441, View in Reaxys; Liu, Xing-Xing; Wu, Zhao-Yang; He, Yong-Qin; Zhou, Xiao-Qiang; Hu, Ting; Ma, Chao-Wei; Huang, Guo-Sheng; Advanced Synthesis and Catalysis; vol. 358; nb. 15; (2016); p. 2385 - 2391, View in Reaxys 11 of 49

Description (NMR Spectroscopy)

Chemical shifts; Spectrum

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Nucleus (NMR Spectroscopy)

1H

Solvents (NMR Spectroscopy)

chloroform-d1

Frequency (NMR Spectro- 200 scopy) [MHz] Location

supporting information

Prasad, Pragati K.; Reddi, Rambabu N.; Sudalai, Arumugam; Organic Letters; vol. 18; nb. 3; (2016); p. 500 - 503, View in Reaxys 12 of 49

Description (NMR Spectroscopy)

Chemical shifts; Spectrum

Nucleus (NMR Spectroscopy)

13C

Solvents (NMR Spectroscopy)

chloroform-d1

Frequency (NMR Spectro- 50 scopy) [MHz] Location

supporting information

Prasad, Pragati K.; Reddi, Rambabu N.; Sudalai, Arumugam; Organic Letters; vol. 18; nb. 3; (2016); p. 500 - 503, View in Reaxys 13 of 49

Description (NMR Spectroscopy)

Chemical shifts; Spectrum

Nucleus (NMR Spectroscopy)

1H

Coupling Nuclei

1H

Solvents (NMR Spectroscopy)

chloroform-d1

Frequency (NMR Spectro- 500 scopy) [MHz] Location

supporting information

Nekkanti, Shalini; Veeramani, Karuna; Praveen Kumar, Niggula; Shankaraiah, Nagula; Green Chemistry; vol. 18; nb. 11; (2016); p. 3439 - 3447, View in Reaxys 14 of 49

Description (NMR Spectroscopy)

Chemical shifts; Spectrum

Nucleus (NMR Spectroscopy)

13C

Solvents (NMR Spectroscopy)

chloroform-d1

Frequency (NMR Spectro- 125 scopy) [MHz] Location

supporting information

Nekkanti, Shalini; Veeramani, Karuna; Praveen Kumar, Niggula; Shankaraiah, Nagula; Green Chemistry; vol. 18; nb. 11; (2016); p. 3439 - 3447, View in Reaxys 15 of 49

Description (NMR Spectroscopy)

Chemical shifts

Nucleus (NMR Spectroscopy)

1H

Solvents (NMR Spectroscopy)

chloroform-d1

Frequency (NMR Spectro- 400 scopy) [MHz]

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Zhang, Xueyao; Yang, Honglei; Huo, Yong; Li, Jing; Ma, Jianxin; Ma, Jiantai; Dalton Transactions; vol. 45; nb. 21; (2016); p. 8972 - 8983, View in Reaxys 16 of 49

Description (NMR Spectroscopy)

Chemical shifts; Spectrum

Nucleus (NMR Spectroscopy)

13C

Solvents (NMR Spectroscopy)

chloroform-d1

Frequency (NMR Spectro- 101 scopy) [MHz] Location

supporting information

Liu, Chengkou; Yang, Zhao; Guo, Shiyu; Zeng, Yu; Zhu, Ning; Li, Xin; Fang, Zheng; Guo, Kai; Organic and Biomolecular Chemistry; vol. 14; nb. 36; (2016); p. 8570 - 8575, View in Reaxys 17 of 49

Description (NMR Spectroscopy)

Chemical shifts

Nucleus (NMR Spectroscopy)

1H

Solvents (NMR Spectroscopy)

chloroform-d1

Frequency (NMR Spectro- 300 scopy) [MHz] Original Text (NMR Spec- NMR (300 MHz, CDCl3): α 1.54-1.58 (m, 2H), 1.69-1.73 (m, 4H), 3.28-3.32 (t, 2H, J = 6.0 Hz), troscopy) 3.70-3.72 (m, 2H), 7.48-7.53 (t, 2H, J = 6.0 Hz), 7.61-7.66 (t, 1H, J = 6.0 Hz), 7.93-7.96 (d, 2H, J = 9.0 Hz) Signals [ppm]

1.54 - 1.58; 1.69 - 1.73; 3.28 - 3.32; 3.7 - 3.72; 7.48 - 7.53; 7.61 - 7.66; 7.93 - 7.96

He, Ming-Hui; Su, Mei-Lin; Yu, Zhao-Hui; Chen, Guang-Xue; Zeng, Zhao-Hua; Yang, Jian-Wen; Chinese Chemical Letters; vol. 26; nb. 1; (2015); p. 21 - 25, View in Reaxys 18 of 49

Description (NMR Spectroscopy)

Chemical shifts

Nucleus (NMR Spectroscopy)

13C

Solvents (NMR Spectroscopy)

chloroform-d1

Original Text (NMR Spectroscopy)

13C

Signals [ppm]

24.7; 25.8; 26.6; 42.5; 47.4; 129.2; 129.7; 133.4; 134.9; 165.5; 192

NMR (300 MHz, CDCl3): α 24.7, 25.8, 26.6, 42.5, 47.4, 129.2, 129.7, 133.4, 134.9, 165.5, 192.0

He, Ming-Hui; Su, Mei-Lin; Yu, Zhao-Hui; Chen, Guang-Xue; Zeng, Zhao-Hua; Yang, Jian-Wen; Chinese Chemical Letters; vol. 26; nb. 1; (2015); p. 21 - 25, View in Reaxys 19 of 49

Description (NMR Spectroscopy)

Chemical shifts; Spectrum

Nucleus (NMR Spectroscopy)

1H

Solvents (NMR Spectroscopy)

[(2)H6]acetone

Frequency (NMR Spectro- 600 scopy) [MHz] Location

supporting information

Wedler, Henry B.; Palazzo, Teresa A.; Pemberton, Ryan P.; Hamann, Christian S.; Kurth, Mark J.; Tantillo, Dean J.; Bioorganic and Medicinal Chemistry Letters; vol. 25; nb. 19; (2015); p. 4153 - 4157, View in Reaxys 20 of 49

Description (NMR Spectroscopy)

Chemical shifts; Spectrum

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Nucleus (NMR Spectroscopy)

13C

Solvents (NMR Spectroscopy)

[(2)H6]acetone

Frequency (NMR Spectro- 150 scopy) [MHz] Location

supporting information

Wedler, Henry B.; Palazzo, Teresa A.; Pemberton, Ryan P.; Hamann, Christian S.; Kurth, Mark J.; Tantillo, Dean J.; Bioorganic and Medicinal Chemistry Letters; vol. 25; nb. 19; (2015); p. 4153 - 4157, View in Reaxys 21 of 49

Description (NMR Spectroscopy)

Chemical shifts; Spectrum

Nucleus (NMR Spectroscopy)

1H

Solvents (NMR Spectroscopy)

chloroform-d1

Frequency (NMR Spectro- 400 scopy) [MHz] Original Text (NMR Spec- 1H NMR (400 MHz, CDCl3) α 7.95 (d, J = 7.3 Hz, 2H), 7.64 (t, J = 7.3 Hz, 1H), 7.52 (t, J = 7.6 Hz, troscopy) 2H), 3.72-3.70 (m, 2H), 3.30 (t, J = 5.5 Hz, 2H), 1.71-1.70 (m, 4H), 1.56-1.54 (m, 2H) Location

supporting information

Signals [ppm]

7.95; 7.64; 7.52; 3.7 - 3.72; 3.3; 1.7 - 1.71; 1.54 - 1.56

Kind of signal

d, J = 7.3 Hz, 2H; t, J = 7.3 Hz, 1H; t, J = 7.6 Hz, 2H; m, 2H; t, J = 5.5 Hz, 2H; m, 4H; m, 2H

Shao, Ying; Wu, Zhuhong; Miao, Chunbao; Liu, Li; Journal of Organometallic Chemistry; vol. 767; (2014); p. 60 - 64, View in Reaxys 22 of 49

Description (NMR Spectroscopy)

Chemical shifts; Spectrum

Nucleus (NMR Spectroscopy)

13C

Solvents (NMR Spectroscopy)

chloroform-d1

Frequency (NMR Spectro- 125 scopy) [MHz] Original Text (NMR Spectroscopy)

13C

Location

supporting information

Signals [ppm]

191.9; 165.5; 134.7; 133.3; 129.6; 129; 47.1; 42.2; 26.2; 25.5; 24.4

NMR (125 MHz, CDCl3) 191.9, 165.5, 134.7, 133.3, 129.6, 129.0, 47.1, 42.2, 26.2, 25.5, 24.4

Shao, Ying; Wu, Zhuhong; Miao, Chunbao; Liu, Li; Journal of Organometallic Chemistry; vol. 767; (2014); p. 60 - 64, View in Reaxys 23 of 49

Description (NMR Spectroscopy)

Chemical shifts; Spectrum

Nucleus (NMR Spectroscopy)

1H

Coupling Nuclei

1H

Solvents (NMR Spectroscopy)

chloroform-d1

Frequency (NMR Spectro- 400 scopy) [MHz] Location

supporting information

Deshidi, Ramesh; Kumar, Manjeet; Devari, Shekaraiah; Shah, Bhahwal Ali; Chemical Communications; vol. 50; nb. 67; (2014); p. 9533 - 9535, View in Reaxys

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24 of 49

Description (NMR Spectroscopy)

Chemical shifts; Spectrum

Nucleus (NMR Spectroscopy)

1H

Solvents (NMR Spectroscopy)

chloroform-d1

Frequency (NMR Spectro- 500 scopy) [MHz] Kotha, Surya Srinivas; Chandrasekar, Selvaraj; Sahu, Samrat; Sekar, Govindasamy; European Journal of Organic Chemistry; vol. 2014; nb. 33; (2014); p. 7451 - 7457, View in Reaxys 25 of 49

Description (NMR Spectroscopy)

Chemical shifts; Spectrum

Nucleus (NMR Spectroscopy)

13C

Solvents (NMR Spectroscopy)

chloroform-d1

Frequency (NMR Spectro- 125 scopy) [MHz] Kotha, Surya Srinivas; Chandrasekar, Selvaraj; Sahu, Samrat; Sekar, Govindasamy; European Journal of Organic Chemistry; vol. 2014; nb. 33; (2014); p. 7451 - 7457, View in Reaxys 26 of 49

Description (NMR Spectroscopy)

Chemical shifts; Spectrum

Nucleus (NMR Spectroscopy)

1H

Solvents (NMR Spectroscopy)

chloroform-d1

Temperature (NMR Spectroscopy) [°C]

25

Frequency (NMR Spectro- 600 scopy) [MHz] Location

supporting information

Liu, Le; Du, Liang; Zhang-Negrerie, Daisy; Du, Yunfei; Zhao, Kang; Organic Letters; vol. 16; nb. 21; (2014); p. 5772 5775, View in Reaxys 27 of 49

Description (NMR Spectroscopy)

Chemical shifts; Spectrum

Nucleus (NMR Spectroscopy)

13C

Solvents (NMR Spectroscopy)

chloroform-d1

Temperature (NMR Spectroscopy) [°C]

25

Frequency (NMR Spectro- 150 scopy) [MHz] Location

supporting information

Liu, Le; Du, Liang; Zhang-Negrerie, Daisy; Du, Yunfei; Zhao, Kang; Organic Letters; vol. 16; nb. 21; (2014); p. 5772 5775, View in Reaxys 28 of 49

Description (NMR Spectroscopy)

Chemical shifts; Spectrum

Nucleus (NMR Spectroscopy)

13C

Solvents (NMR Spectroscopy)

chloroform-d1

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Frequency (NMR Spectro- 75 scopy) [MHz] Location

supporting information

Wei, Wei; Shao, Ying; Hu, Huayou; Zhang, Feng; Zhang, Chao; Xu, Yuan; Wan, Xiaobing; Journal of Organic Chemistry; vol. 77; nb. 17; (2012); p. 7157 - 7165, View in Reaxys; Chen, Wen-Lin; Li, Ji-Hui; Meng, Xu; Tang, Dong; Guo, Shuai-Bo; Chen, Bao-Hua; Tetrahedron Letters; vol. 54; nb. 4; (2013); p. 295 - 299, View in Reaxys 29 of 49

Description (NMR Spectroscopy)

Chemical shifts; Spectrum

Nucleus (NMR Spectroscopy)

1H

Solvents (NMR Spectroscopy)

chloroform-d1

Frequency (NMR Spectro- 300 scopy) [MHz] Location

supporting information

Chen, Wen-Lin; Li, Ji-Hui; Meng, Xu; Tang, Dong; Guo, Shuai-Bo; Chen, Bao-Hua; Tetrahedron Letters; vol. 54; nb. 4; (2013); p. 295 - 299, View in Reaxys 30 of 49

Description (NMR Spectroscopy)

Chemical shifts; Spectrum

Nucleus (NMR Spectroscopy)

1H

Solvents (NMR Spectroscopy)

chloroform-d1

Temperature (NMR Spectroscopy) [°C]

19.04

Frequency (NMR Spectro- 400 scopy) [MHz] Location

supporting information

Wang, Hua; Guo, Li-Na; Duan, Xin-Hua; Organic and Biomolecular Chemistry; vol. 11; nb. 28; (2013); p. 4573 - 4576, View in Reaxys 31 of 49

Description (NMR Spectroscopy)

Chemical shifts; Spectrum

Nucleus (NMR Spectroscopy)

1H

Solvents (NMR Spectroscopy)

chloroform-d1

Frequency (NMR Spectro- 400 scopy) [MHz] Location

supporting information

Liu, Jianming; Zhang, Rongzhao; Wang, Shoufeng; Sun, Wei; Xia, Chungu; Organic Letters; vol. 11; nb. 6; (2009); p. 1321 - 1324, View in Reaxys; Zhang, Chun; Zong, Xiaolin; Zhang, Liangren; Jiao, Ning; Organic Letters; vol. 14; nb. 13; (2012); p. 3280 - 3283, View in Reaxys 32 of 49

Description (NMR Spectroscopy)

Chemical shifts; Spectrum

Nucleus (NMR Spectroscopy)

13C

Solvents (NMR Spectroscopy)

chloroform-d1

Frequency (NMR Spectro- 100 scopy) [MHz] Location

supporting information

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Liu, Jianming; Zhang, Rongzhao; Wang, Shoufeng; Sun, Wei; Xia, Chungu; Organic Letters; vol. 11; nb. 6; (2009); p. 1321 - 1324, View in Reaxys; Zhang, Chun; Zong, Xiaolin; Zhang, Liangren; Jiao, Ning; Organic Letters; vol. 14; nb. 13; (2012); p. 3280 - 3283, View in Reaxys 33 of 49

Description (NMR Spectroscopy)

Chemical shifts; Spectrum

Nucleus (NMR Spectroscopy)

1H

Coupling Nuclei

1H

Solvents (NMR Spectroscopy)

chloroform-d1

Frequency (NMR Spectro- 300 scopy) [MHz] Location

supporting information

Wei, Wei; Shao, Ying; Hu, Huayou; Zhang, Feng; Zhang, Chao; Xu, Yuan; Wan, Xiaobing; Journal of Organic Chemistry; vol. 77; nb. 17; (2012); p. 7157 - 7165, View in Reaxys 34 of 49

Description (NMR Spectroscopy)

Chemical shifts; Spectrum

Nucleus (NMR Spectroscopy)

1H

Coupling Nuclei

1H

Solvents (NMR Spectroscopy)

chloroform-d1

Temperature (NMR Spectroscopy) [°C]

25

Frequency (NMR Spectro- 500 scopy) [MHz] Location

supporting information

Zhang, Juan; Wei, Ying; Lin, Shaoxia; Liang, Fushun; Liu, Pengjun; Organic and Biomolecular Chemistry; vol. 10; nb. 46; (2012); p. 9237 - 9242, View in Reaxys 35 of 49

Description (NMR Spectroscopy)

Chemical shifts; Spectrum

Nucleus (NMR Spectroscopy)

13C

Solvents (NMR Spectroscopy)

chloroform-d1

Temperature (NMR Spectroscopy) [°C]

25

Frequency (NMR Spectro- 125 scopy) [MHz] Location

supporting information

Zhang, Juan; Wei, Ying; Lin, Shaoxia; Liang, Fushun; Liu, Pengjun; Organic and Biomolecular Chemistry; vol. 10; nb. 46; (2012); p. 9237 - 9242, View in Reaxys 36 of 49

Description (NMR Spectroscopy)

Chemical shifts

Nucleus (NMR Spectroscopy)

1H

Solvents (NMR Spectroscopy)

chloroform-d1

Frequency (NMR Spectro- 200 scopy) [MHz] Shanmugapriya; Shankar; Satyanarayana; Dahanukar, Vilas H.; Kumar, U. K. Syam; Vembu; Synlett; nb. 19; (2008); p.

2945 - 2950, View in Reaxys

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Description (NMR Spectroscopy)

Chemical shifts

Nucleus (NMR Spectroscopy)

13C

Solvents (NMR Spectroscopy)

chloroform-d1

Frequency (NMR Spectro- 50 scopy) [MHz] Shanmugapriya; Shankar; Satyanarayana; Dahanukar, Vilas H.; Kumar, U. K. Syam; Vembu; Synlett; nb. 19; (2008); p.

2945 - 2950, View in Reaxys 38 of 49

Description (NMR Spectroscopy)

Chemical shifts

Nucleus (NMR Spectroscopy)

1H

Solvents (NMR Spectroscopy)

CDCl3

Frequency (NMR Spectro- 500 scopy) [MHz] Song, Bingrui; Wang, Siyuan; Sun, Caiyun; Deng, Hongmei; Xu, Bin; Tetrahedron Letters; vol. 48; nb. 51; (2007); p. 8982 8986, View in Reaxys 39 of 49

Description (NMR Spectroscopy)

Spectrum

Nucleus (NMR Spectroscopy)

1H

Solvents (NMR Spectroscopy)

CDCl3

Frequency (NMR Spectro- 500 scopy) [MHz] Song, Bingrui; Wang, Siyuan; Sun, Caiyun; Deng, Hongmei; Xu, Bin; Tetrahedron Letters; vol. 48; nb. 51; (2007); p. 8982 8986, View in Reaxys 40 of 49

Description (NMR Spectroscopy)

Spectrum

Nucleus (NMR Spectroscopy)

13C

Solvents (NMR Spectroscopy)

CDCl3

Frequency (NMR Spectro- 125 scopy) [MHz] Song, Bingrui; Wang, Siyuan; Sun, Caiyun; Deng, Hongmei; Xu, Bin; Tetrahedron Letters; vol. 48; nb. 51; (2007); p. 8982 8986, View in Reaxys 41 of 49

Description (NMR Spectroscopy)

Chemical shifts

Nucleus (NMR Spectroscopy)

13C

Solvents (NMR Spectroscopy)

CDCl3

Frequency (NMR Spectro- 125 scopy) [MHz] Song, Bingrui; Wang, Siyuan; Sun, Caiyun; Deng, Hongmei; Xu, Bin; Tetrahedron Letters; vol. 48; nb. 51; (2007); p. 8982 8986, View in Reaxys 42 of 49

Description (NMR Spectroscopy)

Chemical shifts

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Nucleus (NMR Spectroscopy)

1H

Solvents (NMR Spectroscopy)

CDCl3

Frequency (NMR Spectro- 80 scopy) [MHz] Moehrle; Rohn; Westle; Pharmazie; vol. 61; nb. 5; (2006); p. 391 - 399, View in Reaxys 43 of 49

Description (NMR Spectroscopy)

Chemical shifts

Nucleus (NMR Spectroscopy)

13C

Solvents (NMR Spectroscopy)

CDCl3

Frequency (NMR Spectro- 20 scopy) [MHz] Moehrle; Rohn; Westle; Pharmazie; vol. 61; nb. 5; (2006); p. 391 - 399, View in Reaxys 44 of 49

Description (NMR Spectroscopy)

Chemical shifts

Nucleus (NMR Spectroscopy)

13C

Solvents (NMR Spectroscopy)

CDCl3

Frequency (NMR Spectro- 75 scopy) [MHz] Khlebnikov; Novikov; Kusei; Kopf; Kostikov; Russian Journal of Organic Chemistry; vol. 39; nb. 4; (2003); p. 559 - 573, View in Reaxys 45 of 49

Description (NMR Spectroscopy)

Chemical shifts

Nucleus (NMR Spectroscopy)

1H

Solvents (NMR Spectroscopy)

CDCl3

Frequency (NMR Spectro- 300 scopy) [MHz] Khlebnikov; Novikov; Kusei; Kopf; Kostikov; Russian Journal of Organic Chemistry; vol. 39; nb. 4; (2003); p. 559 - 573, View in Reaxys 46 of 49

Description (NMR Spectroscopy)

Chemical shifts

Nucleus (NMR Spectroscopy)

1H

Solvents (NMR Spectroscopy)

CCl4

Frequency (NMR Spectro- 60 scopy) [MHz] Zhou, Tao; Chen, Zhen-Chu; Journal of Chemical Research - Part S; nb. 3; (2001); p. 116 - 117, View in Reaxys 47 of 49

Description (NMR Spectroscopy)

Chemical shifts

Nucleus (NMR Spectroscopy)

1H

Solvents (NMR Spectroscopy)

CDCl3

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Murata, Satoru; Suzuki, Kaoru; Miura, Masahiro; Nomura, Masakatsu; Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999); nb. 2; (1990); p. 361 - 365, View in Reaxys; Imai, Nobuyuki; Achiwa, Kazuo; Chemical and Pharmaceutical Bulletin; vol. 35; nb. 7; (1987); p. 2646 - 2655, View in Reaxys 48 of 49

Description (NMR Spectroscopy)

Chemical shifts

Nucleus (NMR Spectroscopy)

1H

Solvents (NMR Spectroscopy)

CCl4

Ozawa, Fumiyuki; Soyama, Hidehiko; Yanagihara, Hisayoshi; Aoyama, Issei; Takino, Hiroaki; et al.; Journal of the American Chemical Society; vol. 107; nb. 11; (1985); p. 3235 - 3245, View in Reaxys 49 of 49

Description (NMR Spectroscopy)

NMR

Comment (NMR Spectroscopy)

1H

Johansson et al.; Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry; vol. 30; (1976); p. 383,387, View in Reaxys IR Spectroscopy (11) 1 of 11

Description (IR Spectroscopy)

Bands

Solvent (IR Spectroscopy)

potassium bromide

Original Text (IR Spectroscopy)

IR(KBr, cm-1): v 786, 1052, 1286, 1391, 1644, 1745, 2889, 2976, 2964;

Location

Page/Page column 22

Patent; COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH; SUDALAI, Arumugam; PRASAD, Pragati Kishore; REDDI, Rambabu; (31 pag.); WO2017/77550; (2017); (A1) English, View in Reaxys 2 of 11

Description (IR Spectroscopy)

Bands

Solvent (IR Spectroscopy)

potassium bromide

Sharma, Nidhi; Kotha, Surya Srinivas; Lahiri, Nabajit; Sekar, Govindasamy; Synthesis (Germany); vol. 47; nb. 5; (2015); p. 726 - 736; Art.No: SS-2014-T0695-OP, View in Reaxys; Ramanathan, Mani; Kuo, Chun-Kai; Liu, Shiuh-Tzung; Organic and Biomolecular Chemistry; vol. 14; nb. 48; (2016); p. 11446 - 11453, View in Reaxys 3 of 11

Description (IR Spectroscopy)

Bands

Solvent (IR Spectroscopy)

potassium bromide

Location

supporting information

Mai, Wen-Peng; Wang, Hui-Hui; Li, Zhi-Cheng; Yuan, Jin-Wei; Xiao, Yong-Mei; Yang, Liang-Ru; Mao, Pu; Qu, LingBo; Chemical Communications; vol. 48; nb. 81; (2012); p. 10117 - 10119, View in Reaxys; Wang, Hua; Guo, Li-Na; Duan, Xin-Hua; Organic and Biomolecular Chemistry; vol. 11; nb. 28; (2013); p. 4573 - 4576, View in Reaxys; Zhang, Chunyan; Liu, Jianhua; Xia, Chungu; Organic and Biomolecular Chemistry; vol. 12; nb. 47; (2014); p. 9702 - 9706, View in Reaxys; Prasad, Pragati K.; Reddi, Rambabu N.; Sudalai, Arumugam; Organic Letters; vol. 18; nb. 3; (2016); p. 500 - 503, View in Reaxys 4 of 11

Description (IR Spectroscopy)

Bands

Solvent (IR Spectroscopy)

neat (no solvent)

Location

supporting information

Lamani, Manjunath; Prabhu, Kandikere Ramaiah; Chemistry - A European Journal; vol. 18; nb. 46; (2012); p. 14638 14642, View in Reaxys; Wedler, Henry B.; Palazzo, Teresa A.; Pemberton, Ryan P.; Hamann, Christian S.; Kurth, Mark J.; Tantillo, Dean J.; Bioorganic and Medicinal Chemistry Letters; vol. 25; nb. 19; (2015); p. 4153 - 4157, View in Reaxys 5 of 11

Description (IR Spectroscopy)

Bands

Location

supporting information

Copyright © 2018 Elsevier Life Sciences IP Limited except certain content provided by third parties. Reaxys is a trademark of Elsevier Life Sciences IP Limited.

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Chen, Wen-Lin; Li, Ji-Hui; Meng, Xu; Tang, Dong; Guo, Shuai-Bo; Chen, Bao-Hua; Tetrahedron Letters; vol. 54; nb. 4; (2013); p. 295 - 299, View in Reaxys; Kotha, Surya Srinivas; Sekar, Govindasamy; Tetrahedron Letters; vol. 56; nb. 46; (2015); p. 6323 - 6326, View in Reaxys 6 of 11

Description (IR Spectroscopy)

Bands

Location

supporting information

Comment (IR Spectroscopy)

neat liquid

Zhang, Chun; Zong, Xiaolin; Zhang, Liangren; Jiao, Ning; Organic Letters; vol. 14; nb. 13; (2012); p. 3280 - 3283, View in Reaxys 7 of 11

Description (IR Spectroscopy)

Bands

Solvent (IR Spectroscopy)

KBr

Moehrle; Rohn; Westle; Pharmazie; vol. 61; nb. 5; (2006); p. 391 - 399, View in Reaxys; Song, Bingrui; Wang, Siyuan; Sun, Caiyun; Deng, Hongmei; Xu, Bin; Tetrahedron Letters; vol. 48; nb. 51; (2007); p. 8982 - 8986, View in Reaxys 8 of 11

Description (IR Spectroscopy)

Bands

Solvent (IR Spectroscopy)

CHCl3

Khlebnikov; Novikov; Kusei; Kopf; Kostikov; Russian Journal of Organic Chemistry; vol. 39; nb. 4; (2003); p. 559 - 573, View in Reaxys 9 of 11

Description (IR Spectroscopy)

Bands

Solvent (IR Spectroscopy)

KBr

Comment (IR Spectroscopy)

1674 - 1642 cm**(-1)

Imai, Nobuyuki; Achiwa, Kazuo; Chemical and Pharmaceutical Bulletin; vol. 35; nb. 7; (1987); p. 2646 - 2655, View in Reaxys 10 of 11

Description (IR Spectroscopy)

Bands

Solvent (IR Spectroscopy)

KBr

Comment (IR Spectroscopy)

1685 - 1640 cm**(-1)

Ozawa, Fumiyuki; Soyama, Hidehiko; Yanagihara, Hisayoshi; Aoyama, Issei; Takino, Hiroaki; et al.; Journal of the American Chemical Society; vol. 107; nb. 11; (1985); p. 3235 - 3245, View in Reaxys 11 of 11

Description (IR Spectroscopy)

IR

Johansson et al.; Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry; vol. 30; (1976); p. 383,387, View in Reaxys; Glushkov et al.; Zhurnal Organicheskoi Khimii; vol. 10; (1974); p. 304,304,306, View in Reaxys Mass Spectrometry (21) Description (Mass Location Spectrometry)

Comment (Mass Spectrometry)

spectrum

Peak

References

217 m/z; 5 m/z; 112 m/z; 100 m/z; 105 m/z; 54 m/z; 84 m/z; 10 m/z; 77 m/z; 33 m/z; 69 m/z; 61 m/z; 51 m/z; 11 m/z; 41 m/z; 29 m/z

Urbán, Béla; Szabó, Péter; Srankó, Dávid; Sáfrán, György; Kollár, László; Skoda-Földes, Rita; Molecular Catalysis; vol. 445; (2018); p. 195 - 205, View in Reaxys

electrospray ionisa- Paragraph 0048 tion (ESI); high resolution mass spectrometry (HRMS); spectrum

Copyright © 2018 Elsevier Life Sciences IP Limited except certain content provided by third parties. Reaxys is a trademark of Elsevier Life Sciences IP Limited.

Patent; UNIVERSITÉ DE LIÈGE; MONBALIU, Jean-Christophe; GERARDY, Romaric; (30 pag.); WO2018/50546; (2018); (A1) English, View in Reaxys

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high resolution mass spectrometry (HRMS); electron impact (EI); spectrum

Dutta, Pratip Kumar; Dhar, Basabbijayi; Sen, Subhabrata; New Journal of Chemistry; vol. 42; nb.

14; (2018); p. 12062 - 12071, View in Reaxys

high resolution mass spectrometry (HRMS); spectrum

Page/Page column 22

Patent; COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH; SUDALAI, Arumugam; PRASAD, Pragati Kishore; REDDI, Rambabu; (31 pag.); WO2017/77550; (2017); (A1) English, View in Reaxys

high resolution mass spectrometry (HRMS); time-offlight mass spectra (TOFMS); spectrum

supporting information

Mupparapu, Nagaraju; Khan, Shahnawaz; Battula, Satyanarayana; Kushwaha, Manoj; Gupta, Ajai Prakash; Ahmed, Qazi Naveed; Vishwakarma, Ram A.; Organic Letters; vol. 16; nb. 4; (2014); p.

1152 - 1155, View in Reaxys; Kotha, Surya Srinivas; Sekar, Govindasamy; Tetrahedron Letters; vol.

56; nb. 46; (2015); p. 6323 - 6326, View in Reaxys; Liu, Chengkou; Yang, Zhao; Guo, Shiyu; Zeng, Yu; Zhu, Ning; Li, Xin; Fang, Zheng; Guo, Kai; Organic and Biomolecular Chemistry; vol. 14; nb. 36; (2016); p. 8570 - 8575, View in Reaxys

high resolution mass spectrometry (HRMS); spectrum

supporting information

Wedler, Henry B.; Palazzo, Teresa A.; Pemberton, Ryan P.; Hamann, Christian S.; Kurth, Mark J.; Tantillo, Dean J.; Bioorganic and Medicinal Chemistry Letters; vol. 25; nb. 19; (2015); p. 4153 - 4157, View in Reaxys; Prasad, Pragati K.; Reddi, Rambabu N.; Sudalai, Arumugam; Organic Letters; vol.

18; nb. 3; (2016); p. 500 - 503, View in Reaxys

high resolution mass spectrometry (HRMS); electrospray ionisation (ESI); time-offlight mass spectra (TOFMS); spectrum

Nekkanti, Shalini; Veeramani, Karuna; Praveen Kumar, Niggula; Shankaraiah, Nagula; Green Chemistry; vol. 18; nb. 11; (2016); p. 3439 - 3447, View in Reaxys

electrospray ionisa- supporting information (ESI); spection trum

Meena, Samdarshi; Singh, Rohit; Vishwakarma, Ram A.; Aga, Mushtaq A.; Jain, Shreyans K.; Tetrahedron Letters; vol. 57; nb. 33; (2016); p. 3715 3717, View in Reaxys

high resolution mass spectrometry (HRMS); electrospray ionisation (ESI); spectrum

Ramanathan, Mani; Kuo, Chun-Kai; Liu, ShiuhTzung; Organic and Biomolecular Chemistry; vol. 14; nb. 48; (2016); p. 11446 - 11453, View in Reaxys

high resolution mass spectrometry (HRMS); time-offlight mass spectra (TOFMS); liquid chromatography mass spectrometry (LCMS); spectrum

supporting information

Mupparapu, Nagaraju; Battini, Narsaiah; Battula, Satyanarayana; Khan, Shahnawaz; Vishwakarma, Ram A.; Ahmed, Qazi Naveed; Chemistry - A European Journal; vol. 21; nb. 7; (2015); p. 2954 - 2960, View in Reaxys

high resolution mass spectrometry (HRMS); time-offlight mass spectra (TOFMS); spectrum

high resolution mass spectrometry (HRMS); electro-

Sharma, Nidhi; Kotha, Surya Srinivas; Lahiri, Nabajit; Sekar, Govindasamy; Synthesis (Germany); vol. 47; nb. 5; (2015); p. 726 - 736; Art.No: SS-2014T0695-OP, View in Reaxys; Kotha, Surya Srinivas; Chandrasekar, Selvaraj; Sahu, Samrat; Sekar, Govindasamy; European Journal of Organic Chemistry; vol. 2014; nb. 33; (2014); p. 7451 - 7457, View in Reaxys supporting information

Copyright Š 2018 Elsevier Life Sciences IP Limited except certain content provided by third parties. Reaxys is a trademark of Elsevier Life Sciences IP Limited.

Zhang, Chunyan; Liu, Jianhua; Xia, Chungu; Organic and Biomolecular Chemistry; vol. 12; nb. 47; (2014); p. 9702 - 9706, View in Reaxys; Liu, Le; Du,

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spray ionisation (ESI); time-offlight mass spectra (TOFMS); spectrum

Liang; Zhang-Negrerie, Daisy; Du, Yunfei; Zhao, Kang; Organic Letters; vol. 16; nb. 21; (2014); p.

5772 - 5775, View in Reaxys

high resolution mass spectrometry (HRMS); electrospray ionisation (ESI); spectrum

supporting information

Lamani, Manjunath; Prabhu, Kandikere Ramaiah; Chemistry - A European Journal; vol. 18; nb.

46; (2012); p. 14638 - 14642, View in Reaxys; Chen, Wen-Lin; Li, Ji-Hui; Meng, Xu; Tang, Dong; Guo, Shuai-Bo; Chen, Bao-Hua; Tetrahedron Letters; vol.

54; nb. 4; (2013); p. 295 - 299, View in Reaxys

Spectrum

supporting information

Zhang, Chun; Zong, Xiaolin; Zhang, Liangren; Jiao, Ning; Organic Letters; vol. 14; nb. 13; (2012); p.

3280 - 3283, View in Reaxys

electrospray ionisation (ESI); time-offlight mass spectra (TOFMS); spectrum

Wei, Wei; Shao, Ying; Hu, Huayou; Zhang, Feng; Zhang, Chao; Xu, Yuan; Wan, Xiaobing; Journal of Organic Chemistry; vol. 77; nb. 17; (2012); p. 7157 7165, View in Reaxys

liquid chromatography mass spectrometry (LCMS); spectrum

Zhang, Juan; Wei, Ying; Lin, Shaoxia; Liang, Fushun; Liu, Pengjun; Organic and Biomolecular Chemistry; vol. 10; nb. 46; (2012); p. 9237 - 9242, View in Reaxys

EI (Electron impact)

supporting informa- mol peak tion

Liu, Jianming; Zhang, Rongzhao; Wang, Shoufeng; Sun, Wei; Xia, Chungu; Organic Letters; vol.

11; nb. 6; (2009); p. 1321 - 1324, View in Reaxys

mol peak

Shanmugapriya; Shankar; Satyanarayana; Dahanukar, Vilas H.; Kumar, U. K. Syam; Vembu; Synlett; nb. 19; (2008); p. 2945 - 2950, View in Reaxys

Spectrum

electron impact (EI); spectrum

Song, Bingrui; Wang, Siyuan; Sun, Caiyun; Deng, Hongmei; Xu, Bin; Tetrahedron Letters; vol. 48; nb.

51; (2007); p. 8982 - 8986, View in Reaxys

spectrum

Ozawa, Fumiyuki; Soyama, Hidehiko; Yanagihara, Hisayoshi; Aoyama, Issei; Takino, Hiroaki; et al.; Journal of the American Chemical Society; vol. 107; nb. 11; (1985); p. 3235 - 3245, View in Reaxys; Moehrle; Rohn; Westle; Pharmazie; vol. 61; nb. 5; (2006); p. 391 - 399, View in Reaxys Johansson et al.; Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry; vol. 30; (1976); p. 383,387, View in Reaxys

UV/VIS Spectroscopy (1) 1 of 1

Description (UV/VIS Spectroscopy)

Spectrum

Solvent (UV/VIS Spectroscopy)

chloroform

He, Ming-Hui; Su, Mei-Lin; Yu, Zhao-Hui; Chen, Guang-Xue; Zeng, Zhao-Hua; Yang, Jian-Wen; Chinese Chemical Letters; vol. 26; nb. 1; (2015); p. 21 - 25, View in Reaxys

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