Pomyelo 2mg capsule - Pomalidomide | Myapplepharma

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POMALIDOMIDE POMYELO 2MG

DESCRIPTION Pomyelo 2mg is a Natco pharma product which is endorsed by FDA, containing an active anti-cancer drug called Pomalidomide. Pomyelo 2mg is available as orally bioavailable thalidomide derivative with various therapeutic activities such as; Immuno modulatory Anti-angiogenesis Anti-neoplastic Pomyelo 2mg is similar to thalidomide & Lenalidomide with related to decreased rate of serum aminotransferase elevations during treatment. This may leads to severe liver injury. Pomyelo 2mg is involved in the treatment for regression & unmanageable multiple myeloma. Pomyelo 2mg is used in the patients who are failing to response for Lenalidomide treatment. Pomyelo 2mg is used in combination with dexamethasone.

INDICATION The major therapeutic indication of Pomyelo 2mg is involved in the treatment of multiple myeloma.

This treatment is occurred by combining with dexamethasone for reducing the side effect associated with Pomyelo 2mg. Pomyelo 2mg is majorly indicated in patients who are not reacts for prior two therapies like Lenalidomide & proteasome inhibitor.

POMALID WORKS Pomyelo 2mg exhibits various activities like;

Anti-neoplastic activity Prohibits proliferation Promote apoptosis of hematopoietic cancer cells Co adjuvant with dexamethasone in both Lenalidomide sensitive & resistant myeloma cells to activate the tumor cell apoptosis

Immuno modulatory Boosted the T-cells & natural killer cell mediate immunity. The drug is prohibited the formation of proinflammatory cytokines by monocytes.

Anti-angiogenesis Interfere with formation of new vessels and leads to inhibit the cell division.

DRUG INTERACTION Pomalidomide metabolism is mediated by CYP1A2 & CYP3A4. The concomitant use of Pomyelo 2mg with CYP1A2 drugs like Fluoxamine causes elevation of Cmax & AUC of Pomalidomide and concludes as increased concentration of Pomyelo leads to higher extent of adverse effects associated with Pomyelo In this condition, reduce the dose of Pomyelo 2mg and recommended.

STORAGE Pomyelo 2mg should be stored at room temperature of 20° to 25° Protect from light Kept in dry & cool place

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