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HEROIC HUBS

Industry Therapeutic Update from Amneal Pharmaceuticals:

INNOVATION AND OUTCOMES:

A case-based discussion about CREXONT® (carbidopa and levodopa) extended-release capsules

Join us for an insightful discussion led by Drs Espay, Farmer, and Thakkar, who will provide an overview of CREXONT and share their clinical experiences.

This symposium will explore key topics, including the clinical efficacy and safety profile of CREXONT, guidance on initiating dosing, and insights from the speakers’ experiences in clinical practice. This session aims to deepen our understanding of this innovative treatment option.

Saturday, April 5

11:45 am–12:45 pm (PT) I Lunch to be served Room 6DE, Convention Center

Alberto Espay, MD, MSc, FAAN

Movement Disorder Neurologist

Professor of Neurology

Director and Endowed Chair of the Gardner Family Center for Parkinson’s Disease and Movement Disorders

University of Cincinnati Academic Health Center in Cincinnati, OH

Jill Farmer, DO, MPH, FCPP, DipABLM

Movement Disorder Neurologist

Founder, Boro Neurology

Assistant Professor of Neurology

Drexel University College of Medicine in Philadelphia, PA

Sandeep Thakkar, DO

Movement Disorder Neurologist

CEO, Director at Movement Disorder Parkinson’s Disease Specialists

Movement Disorder Sub-Specialist/Neurologist

Hoag Physician Partners in Irvine, CA

Learn more about CREXONT at booth 1707

This program is NOT accredited for continuing education by any organization. Additionally, Industry Therapeutic Updates program content and the views expressed herein are those of the presenting corporate entity and not of the AAN. These programs are not an official part of the 2025 AAN Annual Meeting education or scientific programs, nor are they endorsed by the AAN. The AAN cannot affirm claims pertaining to FDA off-label medication, research use of pre-FDA drugs, or other research information that might be discussed. Industry Therapeutic Updates are industry events.

Education Courses

7:00 a.m.–4:30 p.m.

8:00 a.m.–9:00 a.m.

Controversies in Neurology Plenary Session

9:15 a.m.–11:15 a.m.

Neuroscience in the Clinic Session

12:00 p.m.–2:00 p.m.

Futures in Neurological Research Boot Camp

12:00 p.m.–4:00 p.m.

Society Spotlight

2:30 p.m.–4:30 p.m.

3:30 p.m.–4:30 p.m. Poster Session 1 11:45 a.m.–12:45 p.m.

Industry Therapeutic Updates 11:45 a.m.–12:45 p.m. AAN Business

p.m.–4:30 p.m.

AAN Vision

To be indispensable to our members AAN Mission

To enhance member career fulfillment and promote brain health for all

American Academy of Neurology 201 Chicago Avenue Minneapolis, MN 55415 USA

Phone: (800) 879-1960 (Toll Free) or (612) 928-6000 (International)

Fax: (612) 454-2746

Email: memberservices@aan.com

Website: AAN.com

AAN Chief Executive Officer: Mary E. Post, MBA, CAE

Managing Editor: Angela M. Babb, MS, CAE, APR

Editor: Val Lick

Writers: Ryan Knoke, Sarah Parsons

Designer: Andrew Imholte

Photography: Will Evans

Hot Topics Plenary Session

4:45 p.m.–5:45 p.m.

Commitment to Cures

6:00 p.m.–9:00 p.m.

Pre-registration required

Education Courses

5:00 p.m.–7:00 p.m.

p.m.–5:30 p.m.

Annual Meeting Daily is published by the American Academy of Neurology. The American Academy of Neurology’s registered trademarks and service marks are registered in the United States and various other countries around the world.

CONTROVERSIES IN NEUROLOGY

Experts debate latest controversial issues in this morning’s plenary session

Some of the most current and controversial issues in neurology will be debated during today’s lively Controversies in Neurology Plenary Session, which runs this morning from 9:15 a.m. to 11:15 a.m. in Ballroom 20. The session will showcase six experts engaged in a debate-style format that will see two speakers arguing one side of a single topic, followed by a rebuttal. The session will be moderated by Rashmi B. Halker Singh, MD, FAAN, and Roneil Malkani, MD.

Biomarker-based Diagnosis of Parkinson’s Disease: Are We Ready to Adopt a Biological Definition in Research?

Kathleen Poston, MD, FAAN

Stanford University No

Paolo Calabresi, MD

Blood Pressure Targets in ICH: Should We Go Low?

Policlinico Gemelli Yes

Chitra Venkatasubramanian, MD, MBBS, MSc, FNCS

Stanford University

Kara R. Melmed, MD NYU Langone Health

Should CGRP Antagonists Be First Line for Migraine Treatment?

Andrew Charles, MD

Elizabeth Loder, MD, MPH

Brigham and Women’s Hospital

Continue the conversation at the follow-up popcorn talk!

11:45 a.m.–12:30 p.m.

Trainee Hub (Sails Pavilion: Cityside)

Want to delve deeper into the topics discussed during the Controversies in Neurology Plenary? Trainees are invited to join the plenary moderators for this 45-minute interactive session as they break down the key points from the plenary and explain how they can use and/or relate to the content presented.

Welcome to San Diego!

Your super ideas helped shape the power-packed week ahead

Welcome, neurology superheroes! We’re thrilled you’re here and can’t wait to experience a power-packed week of super science, learning, and connections.

In an ongoing effort to make each AAN Annual Meeting even better than the next, we’ve been listening closely to your feedback and implementing the kind of changes you’ve been asking for. Keep an eye out for these and other exciting improvements throughout the week:

Real-time translation technology

Look for easy-to-use, live AI translation for 60+ languages to make the meeting more accessible and engaging than ever.

Enhanced sustainability efforts

We reduced single-use materials—like signs—on-site and are using compostable or environmentally friendly materials and inks wherever possible. Remember to recycle this issue of Annual Meeting Daily!

Moments of mindfulness + new ways to connect

There are more opportunities than ever to take the wellness breaks your brain needs. Whether you’re into puppy snuggles, yoga, fashion, or showing off your dance moves, you’ll find fun and relaxing ways to kick back, relax, connect, and bring a little levity to your day— every day of the week.

Meet Neurology® Open Access, the newest AAN journal

There’s a new member of the AAN publications family! Neurology® Open Access is a new online journal publishing high-quality, peer-reviewed clinical manuscripts—available for free to readers anywhere. By providing decisionmaking resources for clinicians, clinical researchers, and policymakers, it aims to improve patient care and promote brain health for all.

Other members of the “family” include the AAN’s flagship journal Neurology® ,

its official CME journal Continuum®, its official news source Neurology Today® , and specialty Neurology® journals on topics like clinical practice, education, genetics, and neuroimmunology & neuroinflammation. For your patients and anyone interested in brain health, the AAN offers Brain & Life®, a free magazine, website, and podcast.

Visit the Publications booth in the Sails Pavilion to learn more and browse issues of Continuum!

Speaking up for you and your patients

Did you know that the AAN has the only federal political action committee in Washington, DC, that represents all of neurology? BrainPAC provides bipartisan support for US congressional candidates who stand up for important causes like access to care, reducing regulatory and administrative burden, strengthening the neurology workforce, and supporting neuroscience research and brain health. BrainPAC collects funds only from AAN members who are US citizens or permanent residents—and it uses 100% of those contributions to give you and your patients a greater voice on Capitol Hill. Want to learn more?

• Go to AAN.com/advocacy/BrainPAC.

• Visit us at the BrainPAC booth in the Sails Pavilion.

• Join us tomorrow at 3:30 p.m. at the Practice and Policy Hub in 20D Lobby to hear more about the superpower behind every advocate!

Celebrate BrainPAC’s wins at the Donor Reception!

2025 BrainPAC donors are invited to an exclusive reception on Sunday from 6:00 p.m. to 7:30 p.m. at the San Diego Wine & Culinary Center. The celebration is open to all BrainPAC donors who contributed $500 or more in 2025, and $1,000+ donors will be offered a plus one. Pick up your tickets by Sunday at noon or learn more at the BrainPAC booth.

Even neurology heroes need a brain break!

There’s no Fortress of Solitude at the Annual Meeting, but there are still plenty of ways to unwind and take a break from the hustle and bustle between sessions. Visit Brain Breaks stations located throughout the convention center to make your own unique sculpture from modeling clay, send a note back home to loved ones, or simply stop and reflect.

Just looking for a quieter retreat? Private meeting pods are available in the Sails Pavilion on a first-come, first-served basis, or there are relaxing hammocks in the Wellness Hub.

AAN Business Meeting: Hear from leaders and cast your vote!

When: Saturday, April 5, 3:30 p.m.

Where: 26AB

Eligible* AAN members, please attend the annual Business Meeting to cast your vote on the proposed 2025–2027 Board of Directors slate, plus important bylaws amendments meant to support our organization’s strategic goals! Go to AAN.com/about-the-AAN/Board-of-Directors-slate to view the slate.

This is also a chance for all AAN members to learn about the AAN’s 2024 activities and finances, including progress on the

ACROSS

1 Trace of trauma in CSF

*Voting AAN members are Fellows (FAAN), Neurologist members, and Honorary and Senior members who had voting privileges in their most recent previous category of membership.

3 Very cool tool for assessing spinothalamic function

5 This cervical vertebra has the weight of the world on its shoulders

important goals detailed in the AAN’s five-year strategic plan. Hear presentations from President Carlayne E. Jackson, MD, FAAN; CEO Mary E. Post, MBA, CAE; Treasurer Charles C. Flippen II, MD, FAAN; and others.

Do you have a way with words? Puzzle out today’s crossword!

7 Hippocampal STM-to-LTM strengthener

Take a break to follow these clues and solve today’s crossword puzzle, created by neurologist Sarah Levy, PhD. Find her crosswords in each issue of Annual Meeting Daily! Solutions are on page 19.

8 Organ with the fastest-moving muscle in the human body

ACROSS 1 Trace of trauma in CSF

1 Trace of trauma in CSF

3 Very cool tool for assessing spinothalamic function

5 This cervical vertebra has the weight of the world on its shoulders

7 Hippocampal STM-to-LTM strengthener

8 Organ with the fastest-moving muscle in the human body

1 This exp. design may keep participants and researchers in the dark 2 Latin for

1 This exp. design may keep participants and researchers in the dark

2 Latin for ventricle, “little ____”

3 MRI that might reveal the source of the vertigo

4 Tauopathy with downgaze difficulty, abbr.

6 Tail ending of caud-

1 This exp. design may keep participants and researchers in the dark 2 Latin for

Sarah Levy, PhD

Helpful Hints for Heroes Helpful Hints for Heroes

To reach these links in a flash, go to AAN.com/QuickLinks.

Attendee lunch and happy hour

Attendee lunch is included in your registration fee and served from 11:30 a.m.–1:30 p.m. daily in Exhibit Hall A. Lunches are served in compostable boxes to help with sustainability efforts. Happy hour is time for superheroes to assemble! Grab a drink and join forces with colleagues from 4:30 p.m.–5:30 p.m. in the Sails Pavilion before saving the world at your case studies educational courses. Beverages provided.

Program slides available online

Slides are available online only at AAN.com/Materials or through the AAN Conferences mobile app. You can access program materials through March 1, 2026. (Please note that availability of materials is at the discretion of the specific speaker. Not all sessions will have materials.)

Want more time to review programs?

Add Annual Meeting On Demand to your registration now to save up to 55% and to extend your access to session recordings through March 1, 2026. Check the back of your badge to see if you already have Annual Meeting On Demand. If not, head to registration or email aanamsupport@cmrus.com by May 7, 2025, to add it to your registration.

AANTV Studio

Stop by the AANTV Studio at the top of the escalators by Ballroom 20 (the Plenary Session room) to witness live interviews being recorded for later broadcast on the desktop platform, TV monitors around the convention center, AAN.com/AANTV, and YouTube.

Shuttle information

Scan the QR code to download route-specific shuttle schedules, access a 360-degree street view of the boarding location for each shuttle stop, and download a link to real-time shuttle wait times. Have questions? Call (877) 899-0986.

Access past content

Conference attendees have access to content on the online platform through May 7, 2025. Visit AAN.com/AMOnline and use your 6-digit ID and password to log in. It may take up to 48 hours after course completion for content to become available online.

HOT TOPICS

Cutting-edge translational research showcased at today’s Hot Topics Plenary

Make your way to Ballroom 20 between 4:45 p.m. and 5:45 p.m. this afternoon to hear three outstanding speakers provide summaries of their recent cutting-edge translational research findings related to clinical issues of importance. This session will be moderated by Reena P. Thomas, MD, PhD, FAAN.

Speakers and topics include:

AI and Biomarkers for Early Disease Detection

GLP1 Receptor Agonists: A Panacea or Too Good to Be True?

Implantable BrainComputer Interfaces for the Restoration of Communication and Mobility

Stephanie R. Miller, PhD Gladstone Institutes

Paul Edison, MBBS, PhD, FRCPI Imperial College London

Leigh R. Hochberg, MD, PhD, FAAN Massachusetts General Hospital

Focus on what matters to you with targeted interests

With hundreds of sessions to choose from, narrowing down your Annual Meeting schedule can be challenging. Check out our targeted interest lineups of focused topic-based programming, ranging from educational courses and scientific presentations to networking opportunities and hub talks.

Targeted interests include:

Advanced Practice Providers

If you’re a physician assistant or nurse practitioner looking for the latest information to help you excel in your career, this lineup’s for you.

Artificial Intelligence

Get up to speed on one of today’s hottest—and most controversial—topics.

Brain Health

Explore all things brain health, from combatting burnout to improving wellness and more.

Brain health around the world!

Understand the current international landscape of brain health with “Brain Health: A Global Priority,” Sunday, 3:30 p.m.–5:30 p.m. in room 28D. If you’re curious about neurological associations and exemplary brain health initiatives around the world, this course is a must-attend!

Diversity, Equity, and Inclusion

Delve deep into important and timely issues like health care disparities, women’s health, and more.

Neurohospitalists

Discover tools, tips, and resources to help with the entire spectrum of inpatient care.

Neurology Education

Elevate your students’ learning experience—and your satisfaction as an educator!

Quality and Safety

Unlock the tools to drive meaningful change and improve outcomes.

Spanish Language

Hablas español? These five programs are delivered entirely in Spanish.

Browse interest lineups in the AAN Conferences mobile app or desktop platform by going to “Conference Information” and selecting “Find Session by Targeted Interest.”

Trainees: Check out today’s Research Boot Camp!

Are you a trainee interested in research? Then head to the Hilton San Diego Bayfront, Sapphire ABEF, at noon for the Futures in Neurological Research Boot Camp to see if space is still available for you to garner the connections, information, and tips for success. RSVPs were requested in advance, but organizers said spots may still be available for the half-day event, which concludes at 4:00 p.m.

Topics include how to find mentors and sponsors, trial design, resilience in research, and time management and work-life balance, with lots of time for small group discussion with leading researchers.

Kerstin Bettermann, MD, PhD, FANA, FAAN, member of the AAN Clinical Research Subcommittee, is leading the event. H.E. Hinson, MD, MCR, FAAN, chair of the subcommittee, will review different funding opportunities while highlighting key strategies for your applications.

Speakers include Adrienne Boire, MD, PhD, FAAN; Carolina B. Maciel, MD, MSCR, FAAN; Oluwole O. Awosika, MD, MSCR, FAAN; and Deborah Hall, MD, PhD, FAAN, all members of the subcommittee.

H. E. Hinson, MD, MCR, FAAN, chair of the AAN Clinical Research Subcommittee, speaks with a trainee at the 2024 event.

Deborah Hall, MD, PhD, FAAN, will speak at the boot camp.

TODAY’S HUB HEROICS

Unleash your inner hero at Annual Meeting Hubs!

Prepare to step out of the traditional classroom into the dynamic world of Annual Meeting Hubs. These extraordinary learning opportunities are your chance to connect, collaborate, and learn through unconventional methods. Hubs will empower you to bring fresh perspectives and innovative approaches back to your career, patients, and community. Get ready to soar to new heights and make a heroic impact! Here are today’s highlights:

Academic Hub 27 Lobby

How to Integrate APPs into an Academic Neurology Practice

3:15 p.m.–4:00 p.m.

Advanced practice providers (APPs) contribute significantly to academic neurology to enhance patient care through comprehensive assessments, management of chronic neurological conditions, and contributions to research and educational initiatives. Explore opportunities and challenges for APP integration into academic neurology teams to improve access to care and support the academic mission through their participation in teaching and scholarly activities.

Practice and Policy Hub 20D Lobby

Choosing the Right Artificial Intelligence Tools for My Practice

11:30 a.m.–12:30 p.m.

Gain insights into the practical applications of artificial intelligence (AI) technologies and their impact on patient care, operations, and decision-making.

Neurology of Laughter

3:45 p.m.–4:30 p.m.

Along with an exploration neurological basis of laughter and its role in disorders like stroke, and epilepsy, you’ll be treated to a stand-up comedy performance comedian and juvenile survivor Haley Warren.

Leadership University

Working with the Media and Making Your Messages Resonate: Effective Strategies for Neurologists

1:30 p.m.–2:30 p.m.

Learn how to engage with the media to advance a project or cause by honing your interview skills, delivering effective messages, and responding to tough questions with the experts who help train advocates at the Palatucci Advocacy Leadership Forum.

Wellness Hub

Sails Pavilion: Bayside Introduction to Well-being for Trainees

11:15 a.m.–12:00 p.m.

Discover resources to reduce stress and build resilience from a program director, wellness champion, and neurology resident.

Brazilian Jiu-jitsu

3:30 p.m.–4:15 p.m.

Soak up the basics of Brazilian jiu-jitsu and then try your hand with the experts!

Trainee Hub

Research Hub 11B

The Road Less Travelled: Fulfilling Career Trajectories of IMG Researchers in the US

3:00 p.m.–3:30 p.m.

Hear from non-US researchers on their research journeys in this panel discussion.

Sails Pavilion: Cityside

Bridging Synaptic Gaps: Networking as a Trainee

12:00 p.m.–12:45 p.m.

Demystify the art of networking and learn how to make connections in neurology as a trainee!

Office Hours and Walking Tours

3:30 p.m.–4:30 p.m.

Trainees can drop by to get questions about the Annual Meeting answered, find resources, go over your CV, or connect with neurologists. Look for office hours each day of the meeting. Today, you can join a walking tour and learn about trainee highlights during the week.

Latest technologies and therapies highlighted at Exhibit Hall Presentation Stage, booths

Stop by the Exhibit Hall Presentation Stage located in Hall C, 2200 Aisle, for engaging short-form presentations on emerging technologies and therapies available to help improve overall patient care.

Recognizing the Signs and Symptoms of Friedreich Ataxia

Sunday, April 6

2:00 p.m.–2:20 p.m.

Presented by Biogen

This program will cover the pathophysiology of Friedreich ataxia (FA), key signs and symptoms, differential diagnoses, and genetic testing to confirm FA diagnosis, and is intended for neurologists and health care providers who are interested in learning more about FA.

How do I treat CIDP?

Monday, April 7

12:30 p.m.–12:50 p.m.

Presented by Grifols Shared Services North America

A case presentation of a 45-year-old man who reported progressive arm and leg weakness. The presenter will walk through his decision-making process for diagnosis and treatment including consideration of new modalities for the treatment of chronic inflammatory demyelinating polyneuropathy (CIDP).

Transforming Alzheimer’s Disease Diagnosis with The PrecivityAD2

Blood Test: Seeking to Establish a New Clinical Care Standard for Patients with Memory Impairment

Monday, April 7

3:00 p.m.–3:20 p.m.

Presented by C2N Diagnostics

The PrecivityAD2™ blood test is a breakthrough in Alzheimer’s disease diagnosis, offering high concordance with amyloid PET scan and CSF biomarkers to identify brain amyloid pathology. This test uses highresolution mass spectrometry and multiple proteomic analysis to facilitate an early and accurate diagnosis for patients with cognitive impairment. The discussion will revolve around how the PrecivityAD2 test and other emerging molecular tools are redefining clinical care pathways in neurological medicine.

Innovative Insights: Clinical and Analytical Performance of the Plasma p-Tau217

Quanterix SP-X Chemiluminescent Assay

Monday, April 7

3:30 p.m.–3:50 p.m.

Presented by ARUP Laboratories

ARUP Labs presents about the Quanterix SP-X Human p-Tau217 assay. Topics covered include: Clinical comparison to Aß positron emission tomography (PET) using Fluorbetapir (FBP) in 524 patient samples derived from a cohort with disease prevalence of 65%; assay performance characteristics including method comparison, analyte recovery, precision, analytical sensitivity, analyte stability, and interference/cross-reactivity.

Unmatched Outcomes: Results of the RNS System Post-approval Study for Drug Resistant Focal Epilepsy

Tuesday, April 8

12:00 p.m.–12:20 p.m.

Presented by NeuroPace, Inc.

The RNS System Post-Approval Study is an FDA-requested and reviewed 32-center trial to collect prospective data on the effectiveness and safety of brain-responsive stimulation in 324 adults with drug-resistant focal epilepsy. This presentation will provide study results for seizure reduction at 6 months and 3 years of treatment; a period of seizure freedom of 6 months or more; and, discuss the reasons why outcomes are improved from earlier studies.

Exploring the Clinical Efficacy and Safety or SKYCLARYS (omaveloxolone)

Tuesday, April 8

2:00 p.m.–2:20 p.m.

Presented by Biogen

Join us for a presentation to learn more about the clinical efficacy and safety of SKYCLARYS.

Additionally, the following companies will be offering exciting presentations in their respective booth spaces within the exhibit hall. Stop by these booths for a full list of their scheduled presentations:

• argenx, booth 719

• IPSEN Biopharmaceuticals, booth 713

• Praxis Precision Medicines Inc., booth 2113

• UCB, Inc., booth 1621

Among the variety of Annual Meeting learning opportunities, this week’s lineup of popular Industry Therapeutic Updates (ITUs) offer a unique chance for the Academy’s industry partners to highlight progress within their respective pipelines and current therapies for patients with neurological disease. Check out these opportunities throughout the week designed to arm attendees with useful knowledge and tools to improve patient care.

When can I attend ITUs?

Evening ITUs

Catch these programs Monday and Tuesday evenings from 6:00 p.m. to 8:00 p.m. at the Marriott Marquis or Hilton San Diego Bayfront.

Lunchtime ITUs

Look for lunchtime ITUs taking place every day of the meeting in Ballrooms 6B-E of the San Diego Convention Center between 11:45 a.m. and 12:45 p.m.

How can I find ITUs?

• Use the AAN Conferences mobile app to quickly search schedules; sessions are clearly delineated as being industry related and include the hosting company’s name

• Find the schedule in the Room Locator

• Connect with hosting companies prior to the meeting or on-site in their exhibit space

Regional Injection Training and Education program

Participate in an interactive, hands-on cadaver workshop, presented by AbbVie Medical Institute. The program will occur in a mobile lab located directly in the exhibit hall and will provide injection training and discussions about real-world challenges in Adult Spasticity, Cervical Dystonia, and Chronic Migraine management. Registration for these sessions must be done in person. Registration opens at 8:00 a.m. on Sunday. Visit the cadaver workshop registration booth located in Exhibit Hall D.

Today’s Neuroscience in the Clinic session to explore repeat expansion disorders in neurological disease

Those looking for the latest information on repeat expansion disorders in neurological disease will want to make their way to 31C today between 12:00 p.m. and 2:00 p.m. for Neuroscience in the Clinic. Directors Brent L. Fogel, MD, PhD, FAAN, and David Pellerin, MD, will be joined by expert faculty Christel Depienne, PhD, and Andrea Cortese, MD, PhD, and abstract presenters Yi-Chung Lee, MD, FAAN, and Richard Albertson, MD, PhD, to discuss these disorders’ molecular basis, pathogenesis, clinical presentation, differential diagnosis, diagnostic evaluation, and management, including genetic testing strategies and updates on newly identified disorders and other breakthroughs in the field. Particular attention will be given to hereditary cerebellar ataxias, neuromuscular disorders, and familial adult myoclonic epilepsy.

“Attendees will gain insights into the rapidly evolving field of repeat expansions in neurological disorders,” said Pellerin.

“By exploring breakthroughs in diagnosis, hereditary ataxias, neuromuscular disorders, and familial adult myoclonic epilepsy, this session aims to equip attendees with the knowledge and tools to bridge gaps and advance patient care in this important area of neurology.”

The session will end with a panel discussion along with opportunity for questions. Attendees may claim two CME credits.

Fogel

Pellerin

Depienne

Cortese

Lee

Albertson

Harness the power of the Annual Meeting through the mobile app and desktop platform

Seamlessly tap into this week’s super offerings in whatever way works best for you—in person or online! When you download the AAN Conferences app or log in through your web browser, you harness the power of seamless synchronization to get the biggest bang from your meeting experience.

With this powerful technology you can:

• View live session broadcasts and recordings

• Build your personalized agenda and sync it to your calendar

• Access program materials* and claim CME

• View maps for easy navigation throughout the San Diego Convention Center

• Turn on push notifications for helpful conference reminders and tips

Need help? Stop by Meeting Information and Tech Support in B Lobby and near Ballroom 20. For additional information—and to access the meeting virtually through a web browser— visit AAN.com/AMOnline.

* Availability of program materials is at the discretion of the specific speaker. Not all sessions will have materials.

How can you access the meeting’s real-time translation technology?

To take advantage of the Annual Meeting’s live AI translation feature, simply scan the QR code on your program’s walk-in slide or click the link in the session listing within the mobile app. You’ll go straight to the Wordly site, where you can choose from 60+ transcription languages, switch between languages at any time, or select audio translation.

Super speed or not, you can raise money for

brain health!

Want to join in on an exciting Annual Meeting tradition—and take in some San Diego sights along the way? Sign up for the 5K Run/ Walk for Brain Health, taking place bright and early Tuesday from 6:30 a.m. to 8:00 a.m. at the Embarcadero Marina Park North.

Registration costs $50, with proceeds going to support the AAN Brain Health Initiative. Register by noon Monday in D Lobby near registration, where you’ll also pick up your t-shirt and other race materials. Thank you for helping support brain health for all!

The Run/Walk for Brain Health is sponsored by Sanofi, argenx, Xenon Pharmaceuticals, and ARUP Laboratories.

Today’s Society Spotlight focuses on hot topics in cerebrovascular disease

The AAN is partnering with the American Heart Association and American Stroke Association for today’s Society Spotlight session from 2:30 p.m. to 4:30 p.m. in room 25A. Participants will hear updates on the cutting-edge science of hot topics in cerebrovascular disease from speakers giving encore presentations of top research presented at the partnering societies’ meetings. Select talks will emphasize basic, clinical, and translational science as they evolve toward a more complete understanding of cerebrovascular disease with the overall goal of developing more effective prevention and treatment.

Attendees should become familiar with the principles from the sciences of behavioral economics and decision neuroscience to provide insight into opportunities for achieving healthy lifestyle, and learn how risk assessment, decision making, and stress response can be optimized to maximize overall health and brain health.

Presentations and speakers include:

Healthy Heart/Healthy Brain: Cardiac Contributions to Neurodegenerative Disease

Fernando D. Testai, MD, PhD, FAAN

2:30 p.m.–2:50 p.m.

Healthy Lifestyles Through the Lifecourse: The Key to Cardiovascular and Brain Health

Norrina Allen, PhD

2:50 p.m.–3:10 p.m.

Measuring Brain Health: The State of the Art

Sandi Chapman, PhD

3:10 p.m.–3:30 p.m.

Neuroscience of Healthy Decision Making

Michael Platt, PhD

3:30 p.m.–3:50 p.m.

AHA/ASA 2024 Guideline on Primary Prevention of Ischemic Stroke: Importance of Lifestyle Factors

Amy T. Towfighi, MD

3:50 p.m.–4:10 p.m.

A Behavioral Economics Approach to Making Healthy Decisions

Kevin Volpp, MD, PhD

4:10 p.m.–4:30 p.m.

Join Robert Hauser, MD, MBA, FAAN and Stuart Isaacson, MD, FAAN as they discuss a NEW treatment for Parkinson’s.

Stuart Isaacson, MD, FAAN

Robert Hauser, MD, MBA, FAAN

VOICES OF THE ANNUAL MEETING

What are you looking forward to the most at the Annual Meeting?

I’m looking forward the most to Advocacy Day on Sunday. It’ll be a great opportunity to learn about advocacy in real practice from all the leaders in our organization, engage with members, and really serve our patients best.

Garrett Conyers, MD, MPP

What are you looking forward to the most at the Annual Meeting?

Catching up with friends and collaborators, spending time in the Neurology Education Room, and just getting to see everyone and enjoy California. What is your neurology superpower?

Writing #ContinuumCase questions on X, which you can follow if you follow the @ContinuumAAN account!

Casey Albin, MD

What are you looking forward to the most at the Annual Meeting?

Sharing time with trainees and helping them enjoy the meeting—the same way I enjoyed the meeting when I was in the early years of my career.

What is your neurology superpower?

Delivering compassionate care to patients with neurological diseases.

Victor Del Brutto, MD

Powerful research packs a punch at Poster Hall opening today

The latest research will be on display starting at 11:45 a.m. in Exhibit Hall A for this year’s always popular Annual Meeting Poster Hall. It’s here you’ll find all-digital displays showcasing powerful research results with 12 author standby opportunities for questions taking place today through Wednesday at 12:45 p.m. Topic-related “neighborhood” groupings will help you easily navigate your way to the research of most interest to you!

Solutions to today’s crossword puzzle

Did you solve today’s neurology-themed crossword puzzle, located on page 7? Check your answers here!

Sunny San Diego’s super sights, sounds, and tastes!

Welcome to San Diego! Don’t forget to make time this week to take in some of San Diego’s spectacular surroundings. The Annual Meeting is the perfect spot from which to launch your adventure, too, with the San Diego Convention Center offering incredible panoramic views of San Diego Bay. From there, it’s just minutes to some of the best this sunny city has to offer:

Historic Gaslamp Quarter

Explore 16 blocks of historic Victorian-era buildings and modern skyscrapers, home to 100 of the city’s finest restaurants, pubs, nightclubs, boutiques, and more. It’s also the location of the Annual Meeting Party on Sunday, April 6!

Seaport Village

Meander four miles of cobblestone pathways bordered by ponds, lakes, fountains, and colorful landscaping while shopping, eating, and taking in the cool coastal breezes and stunning views of the Coronado Bridge.

Horton Plaza

Located in the heart of Downtown San Diego, this world-class, open-air urban plaza and central community gathering space is an innovation hub for science, technology, arts, entertainment, and education.

USS Midway Museum

One of San Diego’s most popular family attractions! Don’t miss this once-in-a-lifetime opportunity to explore a historic aircraft carrier and more than 30 restored aircraft. Activities for all ages include self-guided audio tours, theater, flight simulators, climb-in aircraft, ejection seats and cockpits, guided tours of the bridge, and more.

Petco Park

Baseball fan or not, Petco Park is spectacular in every way. Its magnificent architecture celebrates the sea, sky, natural beauty, cultural diversity, and unique spirit of the region.

World-famous San Diego Zoo

Get an up-close experience with thousands of rare and endangered animals representing hundreds of species and subspecies. At 100 acres, this is one of the country’s largest and most impressive zoos.

From practice efficiencies to puppies, treat yourself to wellness!

The Annual Meeting is the world’s largest gathering of neurology professionals, with unmatched science, education, and networking—but even in the rush of the conference, there are opportunities to focus on you.

Visit the Wellness Hub (Sails Pavilion: Bayside) throughout the meeting for educational sessions on improving wellness in your career, as well as ways to rejuvenate and connect. You can stop by to rest on a hammock, check out the sensory area, or enjoy some yoga or pickleball. (Not sure what that is? Pickleball lessons take place each day in the Sails Pavilion from 12:30 p.m. to 1:00 p.m.!)

Looking for a break to chat and have fun? Visit 2:00 p.m.–3:00 p.m. Monday for the Wellness Hub Social Hour, followed by a salsa dancing session open to all.

Annual Meeting sessions for well-being

From practice efficiencies that give you more time for joy in your career to simple ways to unwind, these sessions were designed with wellness in mind.

How to Love Your Job Again: Discover Your Values, Establish Practice Efficiencies, and Be Done by Dinner Sunday, 1:00 p.m.–3:00 p.m. in 28E.

Run/Walk for Brain Health Tuesday, 6:30 a.m.–8:00 a.m. Register by noon Monday to participate.

Puppy Park in the Exhibit Hall Sunday through Wednesday, 11:30 a.m.–4:00 p.m.

Brain Breaks

Find Brain Break stations across the convention center to make a modeling clay sculpture or send a note home.

Charcot’d Breakers puzzle series part deux starts today!

Embark on a magnifique journey into the world of neuroscience with “Charcot’d Breakers,” a super puzzle series and nod to the French father of neurology, Jean-Martin Charcot. Designed exclusively for neurologists and brain enthusiasts, this series offers a unique blend of cerebral challenges, each crafted to stimulate your cognitive prowess and test the depths of your neurological knowledge. Look for the “Charcot’d Breakers” signs on the upper level of the San Diego Convention Center. Complete 10 puzzles (order irrelevant) to receive 10 clues to help solve the final puzzle located near Meeting Information outside Ballroom 20.

Successfully crack the codes, and you’ll join the esteemed group of Charcot’d Breakers, with all the bragging rights—and a small prize—that come with the designation! Allez, les héros du cerveau!

Celebrate these education heroes! 2025 AAN Education Award recipients

These education heroes soared to new heights—empowering minds and inspiring greatness. Join us in recognizing the 2025 AAN education award recipients.

A.B. BAKER AWARD FOR LIFETIME ACHIEVEMENT IN NEUROLOGIC EDUCATION

Funded by an endowment created by matching funds from the A.B. Baker Family Trust and Novartis Pharmaceuticals.

Rana R. Said, MD, FAAN University of Texas Southwestern Medical Center, Dallas, TX

A. B. BAKER TEACHER RECOGNITION AWARD

Nada G. Abou Fayssal, MD, FAAN

New York University, Brooklyn, NY

Margaret Adler, MD Harbor-UCLA Medical Center, Torrance, CA

Pria Anand, MD

Boston University Medical Center, Boston, MA

Erika J. Axeen, MD

University of Virginia, Charlottesville, VA

Jennifer Bain, MD, PhD Columbia University, New York, NY

Grayson B. Beecher, MD

University of Alberta, Edmonton, AB, Canada

Maria Bruzzone Giraldez, MD, MSc, FAAN

University of Florida, Gainesville, FL

Esther Bui, MD

Toronto Western Hospital, Toronto, ON, Canada

Katie L. Bullinger, MD, PhD Emory University, Atlanta, GA

Ivan D. Carabenciov, MD

Mayo Clinic Rochester, Rochester, MN

Olimpia Carbunar, MD

University of Miami, Miami, FL

Courtney S. Casserly, MD, FAAN

London Health Sciences Center, London, ON, Canada

Pablo R. Castillo, MD, FAAN

Mayo Clinic Florida, Jacksonville, FL

Krishna Nalleballe, MD, FAAN

UAMS Medical School, Little Rock, AR

Shivika Chandra, MD, FAAN

University of Texas Health Science Center at Houston, Houston, TX

Hamza Coban, MD

UConn Health, Farmington, CT

Sarah Conway, MD

Brigham and Women’s Hospital, Boston, MA

Sudhir V. Datar, MD

Wake Forest Baptist Medical Center, Winston-Salem, NC

Jeffrey Dewey, MD

Yale University, New Haven, CT

Ahmed M. Kamal Bayoumy, MBBCh, FEBN

King Saud Medical City, Riyadh, Saudi Arabia

Yasir El-Sherif, MD

Northwell Health, Staten Island, NY

Danison Emmerson, MD

University of Massachusetts Medical School/UMass Memorial Medical Group, Marlborough, MA

Sarah E. Fredrich, MD

University of Maryland, Baltimore, MD

Jessica Frey, MD

West Virginia University, Morgantown, WV

Alfred T. Frontera, Jr., MD

University of South Florida College of Medicine, Tampa, FL

Tanu Garg, MD

Houston Methodist Hospital, Houston, TX

Jessica Gautreaux, MD, FAAN

Louisiana State University Health Sciences Center New Orleans, New Orleans, LA

Raghav Govindarajan, MD, FAAN

HSHS St. Elizabeth Medical Group, O’Fallon, IL

Saad Hasan, MD

University of Louisville, Louisville, KY

Thomas C. Head, MD

University of Alabama at Birmingham, Birmingham, AL

Lauryn Hemminger

University of Rochester, Rochester, NY

Christopher Hollen, MD

Oregon Health & Science University, Portland, OR

Nicholas Janocko, MD

Weill Medical College of Cornell University, New York, NY

Emily C. Johnson, MD

Trinity Health Hauenstein Neurosciences, Grand Rapids, MI

Mohammed Kananeh, MD

Hackensack University Medical Center, Hackensack, NJ

Peter Kang, MD, MSCI

Washington University School of Medicine, Saint Louis, MO

Akshat Katyayan, MD

Baylor College of Medicine/Texas Children’s Hospital, Houston, TX

Yasmin Khakoo, MD, PhD, FAAN, FCNS, FAAP

Memorial Sloan Kettering Cancer Center, New York, NY

William A. Kilgo, MD University of South Alabama, Mobile, AL

Eric H. Kossoff, MD

Johns Hopkins University, Baltimore, MD

Shivakrishna Kovi, MD, MBBS Unity Point Health, Des Moines, IA

Jeremy Kulacz, MD

SIU Neuroscience Center, Springfield, IL

Achal K. Srivastava, MD, DM

All India Institute of Medical Sciences in New Delhi, New Delhi, India

Vishakhadatta Mathur Kumaraswamy, MD University of Kentucky, Lexington, KY

Sushil S. Lakhani, MD

The Ohio State University Wexner Medical Center, Columbus, OH

David P. Lerner, MD

One Brooklyn Health, Brooklyn, NY

Ali Mahta, MD

Brown University, Providence, RI

Camille Malatt, MD

Cedars-Sinai Medical Center, Los Angeles, CA

Soe S. Mar, MD, FAAN

Washington University School of Medicine, Saint Louis, MO

Rohit A. Marawar, MD, FAAN

Wayne State University - Detroit Medical Center, Detroit, MI

Heather R. McKee, MD University of Cincinnati Medical Center, Cincinnati, OH

Nancy A. Mcnamara, MD

C.S. Mott Children’s Hospital, Ann Arbor, MI

Mayra Montalvo Perero, MD University of Florida, Gainesville, FL

Debra Moore-Hill, MD, FAAN

Augusta University, Medical College of Georgia, Augusta, GA

Seniha N. Ozudogru, MD University of Pennsylvania, Philadelphia, PA

Michael L. Palm, MD, FAAN UT Health San Antonio, San Antonio, TX

Elizabeth M. Perelstein, MD

Brown University, Providence, RI

Sharoon Qaiser, MD, MBBS University of Kentucky, Lexington, KY

Jeffrey Rosenfeld, MD, PhD, FAAN

Loma Linda University Medical School, Loma Linda, CA

Kasser Saba, MD

Atrium Health, Charlotte, NC

Sarada Sakamuri, MD

Stanford University, Stanford, CA

Devorah Segal, MD, PhD

NYU Langone Health, New York, NY

Suma Shah, MD

Duke University Medical Center, Durham, NC

Helen Shi, MD

Emory University Hospital, Atlanta, GA

Susan Shin, MD

Mount Sinai Hospital, New York, NY

Emily Singer, MD

University of Louisville, Louisville, KY

Sara J. Stern-Nezer, MD University of California, Irvine, Orange, CA

Charlotte J. Sumner, MD, FAAN

Johns Hopkins University, Baltimore, MD

Evan Templeton, MD

Indiana University School of Medicine, Indianapolis, IN

Mark A. Terrelonge, Jr., MD

University of California, San Francisco, San Francisco, CA

Jigisha Thakkar, MD

Loyola University, Maywood, IL

Sreenath Thati Ganganna, MD

University of Iowa Hospitals and Clinics, Iowa City, IA

Neeharika Thottempudi, MD University of Nevada, Reno, NV

Dana L. Vanino, DO Geisinger Medical Center, Danville, PA

Uttam Verma, MBBS

University of Oklahoma, Oklahoma City, Oklahoma

Tuhin Virmani, MD, PhD, FAAN

University of Arkansas for Medical Sciences, Little Rock, AR

Ericka S. Wong, MD

Jefferson Health, Philadelphia, PA

Kara J. Wyant, MD

University of Michigan, Ann Arbor, MI

Derek Yuan, MD

UHS Wilson Medical Center, Johnson City, NY

CLERKSHIP DIRECTOR INNOVATION AWARD

Alexandra E. Hovaguimian, MD

Beth Israel Deaconess Medical Center, Boston, MA

CLERKSHIP DIRECTOR TEACHING AWARD

Joanne M. Wojcieszek, MD

Indiana University Health Neuroscience Center, Indianapolis, IN

CLERKSHIP EDUCATION COORDINATOR RECOGNITION AWARD

Ana Juarez

Rush University, Chicago, IL

DIRECTOR

MENTORSHIP LEADERSHIP PROGRAM

Supported in part by LivaNova.

Joy Chan, MD

University of California, Los Angeles, Los Angeles, CA

Meeryo Choe, MD, FAAN

UCLA, David Geffen School of Medicine, Los Angeles, CA

Veronica K. Penyak Cipriani, MD

University of Chicago, Chicago, IL

Tanu Garg, MD

Houston Methodist Hospital, Houston, TX

Douglas J. Gelb, MD, PhD, FAAN

University of Michigan, Ann Arbor, MI

Holli A. Horak, MD, FAAN

University of Arizona, Tucson, AZ

Alexandra E. Hovaguimian, MD

Beth Israel Deaconess Medical Center, Boston, MA

Bing Liao, MD

Houston Methodist Hospital, Houston, TX

Marissa C. Natelson Love, MD, FAAN

University of Alabama at Birmingham, Birmingham, AL

Max R. Lowden, MD, FAAN

Penn State Hershey Medical Center, Hershey, PA

Marisa McGhee, MD

Atrium Wake Forest Baptist Hospital, Winston-Salem, NC

Michael L. Palm, MD, FAAN

University of Texas Health San Antonio, San Antonio, TX

Claudia A. Perez, MD

Neurocritical Care Associates of Ft Worth, Fort Worth, TX

Tania Reyna, MD, FAAN

University of Texas San Antonio, San Antonio, TX

Igor Rybinnik, MD

Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ

Courtney Seebadri-White, MD

Thomas Jefferson University, Philadelphia, PA

Colleen Bevevino Tomcik, MD, FAAN

University of Rochester, Rochester, NY

Ann Van De Walle Jones, MD

Indiana University, Bloomington, IN

ENHANCED RESIDENT LEADERSHIP PROGRAM

Supported in part by Alexion Pharmaceuticals, Inc., and LivaNova USA, Inc.

Sarah Bou Reslan, MD

New York University, Langone Medical Center, New York, NY

Emily R. Fisher, MD

University of Virginia Hospital, Charlottesville, VA

Tanner Hoke, MD

St. Louis Children’s Hospital, St. Louis, MO

Lachelle V. Hood, MD

University of Cincinnati Medical Center, Cincinnati, OH

Riley Kessler, MD

Children’s Hospital of Philadelphia, Philadelphia, PA

Clare M. Lambert, MD

Yale-New Haven Medical Center, New Haven, CT

Christina Law, MD, MEd Mount Sinai West, New York, NY

Emily G. Lubas, MD

Thomas Jefferson University, Philadelphia, PA

Jorge E. Patino Murillas, MD

The University of Texas Health Science Center at Houston McGovern Medical School, Houston, TX

Michael A. Perez, MD University of Pennsylvania, Philadelphia, PA

Rajapillai Pillai, MD, PhD

Massachusetts General Hospital, Boston, MA

Luis G. Rueda Carrillo, MD

Wellstar MCG Health, Augusta, GA

Marinos G. Sotiropoulos, MD

Massachusetts General Hospital, Boston, MA

Nicholas J. Wasko, MD, PhD University of Iowa, Iowa City, IA

Sanam Zarei, MD

Children’s National Medical Center, Washington, DC

FELLOWSHIP DIRECTOR

RECOGNITION AWARD

Chilvana V. Patel, MBBS, FAAN University of Texas Medical Branch Hospitals, Galveston, TX

Sara M. Schaefer, MD, FAAN Yale University, New Haven, CT

FRANK A. RUBINO AWARD FOR EXCELLENCE IN CLINICAL NEUROLOGY TEACHING

Funded by Mayo Clinic Frank A. Rubino, MD Development Fund.

Gary S. Gronseth, MD, FAAN University of Kansas, Kansas City, KS

NEUROSCIENCE

COURSE DIRECTOR EXCELLENCE AWARD

Thomas Thesen, PhD Geisel School of Medicine at Dartmouth, Hanover, NH RESIDENCY EDUCATION COORDINATOR RECOGNITION AWARD

Kelly E. Parm

Trinity Health Grand Rapids, Grand Rapids, MI

Cassaundra Tucker, CTAGME Medical University of South Carolina, Charleston, SC RESIDENCY PROGRAM DIRECTOR RECOGNITION AWARD

Alexandra O. Duffy, MD, FAAN University of California, Davis Health, Sacramento, CA

Jeffrey B. Ratliff, MD, FAAN Thomas Jefferson University, Philadelphia, PA

RESIDENT

& FELLOW WRITING AWARD

Sponsored by Neurology® Resident & Fellow Section.

Hillary Mullan, MD

NYU Langone Neurology and NYU Grossman School of Medicine, New York, NY

Industry Therapeutic Update from The Global CEO Initiative on Alzheimer’s Disease

Blood-Based Biomarkers for Alzheimer’s Disease: A New Era in Diagnosis and Clinical Care

This session will highlight the latest advancements in biomarker research, focusing on how high-performing blood tests are enabling earlier and more accurate detection of Alzheimer’s pathology. Attendees will gain insights into the practical application of these biomarkers in clinical settings, including their role in diagnosing cognitive impairment, guiding the use of treatments, and improving ongoing patient care and management.

11:45AM – 12:45PM | San Diego Convention Center 6CF | AAN Annual Meeting

Doors will open at 11:15AM. Lunch will be provided.

And meet CEOi in the Exhibit Hall at Booth 1432!

Check out this QR code to learn more about CEOi

Drew Holzapfel The Global CEO Initiative on Alzheimer’s Disease

Kavita Nair University of Colorado