2017 AAN Annual Meeting Science Program

Page 80

Poster Sessions

Poster Session I

PARKINSON’S DISEASE: BIOMARKERS AND GENETICS

Patients —Mahsa Dolatshahi, Seyyed

P1.001 Genome-wide Association for

P1.012 Lewy Body and Tau pathology

the Park10 Locus in Iopathic, Autopsyproven, Lewy Body Parkinson Disease and Autopsy-Proven Controls —Jeffery

Vance, Karen Nuytemans, Lissette Gomez, William Scott, Gary Beecham, Djordje Gveric, Eden Martin, APDGC Consortium

P1.002 Genetic analysis of the

Glucocerebrosidase gene in Indian patients with Parkinson’s disease —Ravi YADAV, Saketh Kapoor, Mayank Madhukar, Rajini Manja, Pramod Pal, Arun Kumar

P1.003 Interplay Between LRRK2 Action in Neurons and Macrophages in Mediating α-Synuclein linked Neurodegeneration —Hisham

Abdelmotilib, Andrew West, Laura VolpicelliDaly, Ashley Harms

Shayan PourMirbabaei, Mehdi Yaseri, Aida Kamalian, Mohammad Hadi Aarabi

in a patient with parkinsonism, cognitive decline, rapid progression and the GBA1 T369M variant —Hannah Walters, Rachel Saunders-Pullman, John Crary, Deborah Raymond, Susan Bressman

Thomas Beach, Tatiana Foroud, Charles Adler, Holly Riss, Dixie Ecklund, Chelsea CaspellGarcia, Kuldip Dave, Sampada Deshpande, Shirley Lasch, Vanessa Arnedo, Lindsey Riley, Danna Jennings, Brit Mollenhauer, Lama Chahine

Houghton

P1.005 Baseline Cerebrospinal Fluid

P1.015 Neurons with oscillatory

Biomarkers Associated with Longitudinal Cognitive and Functional Decline in Early Parkinson’s Disease —Olga Kofman, David

activity in the basal ganglia and the ventral thalamus in patients with Parkinson’s disease —Ping Zhuang, Mark

Wolk, Corey McMillan

Hallett, Gang Du, Yuqing Zhang, Yongjie Li

P1.006 Elevated GM3 Plasma

P1.016 Objective gait parameters as

Chan, Adler Perotte, Bowen Zhou, Christopher Liong, Evan Shorr, Karen Marder, Un Kang, Cheryl Waters, Oren Levy, Yimeng Xu, Hong Bin Shim, Itsik Pe’er, Gilbert Di Paolo

Tuhin Virmani

SUNDAY

and Plasma-Based miRNA Levels in Parkinson’s disease Patients —Dominic

Facciponte, Jackson Storm, Haley Grigel, Jacob Rauh, Patricia Henegan, Angeline Andrew, Mary Feldman, Stephen Lee, Elijah Stommel

P1.008 Functional MAOB gene

intron 13 polymorphism predicts putaminal dopamine turnover in de novo Parkinson’s disease —Matthias Lohle, Graziella Mangone, Martin Wolz, Bettina Beuthien-Baumann, Liane Oehme, Jorg Van Den Hoff, Jorg Kotzerke, Heinz Reichmann, Jean Christophe Corvol, Alexander Storch

P1.009 Serum Oxidant and

Antioxidant Status of Patients with Parkinson’s Disease —Mustafa Yurtdas,

Tahir Kurtulus Yoldas, Burcu Gokce Cokal, Nalan Gunes, Zahide Esra Durak, Selda Keskin Guler, Bilal Aytac, Ilker Durak, Mehmet Ilker Yon, Aysegul Akyuz, Ufuk Atak Donger

P1.010 Enteric neurons reveal

substantial ex vivo mitochondrial changes in Parkinson’s disease —

Paul Antony, Aidos Baumuratov, Marek Ostaszewski, Feng He, Luis Salamanca, Laurent Antunes, Jos Weber, Laura Longhino, Pascal Derkinderen, Rudi Balling, Werner Koopman, Nico Diederich

P1.011 An Exploratory Study of

Associations Between longitudinal Changes of different CSF Biomarkers in Early, Drug-naïve Parkinson’s Disease

P1.145–222

G

P1.223–250

D

P1.101–110

Poster Discussion

C

P1.081–100

P1.014 Comparison of quantitative

Theresa Bartels, Susan Lindquist

P1.007 Environmental Risk Factors

F

E

P1.111–144

Multisite Tissue and Biofluid Sampling for Synuclein in Parkinson’s Disease: The Systemic Synuclein Sampling Study (S4) —Carly Linder, Christopher Coffey,

measures of Pupil Light Reflex measured using Automated Pupillometer in patients with Parkinson’s disease and controls —Robin Ulep, Fawad Khan, David

Concentration in Parkinson’s Disease: a Lipidomics Analysis —Roy Alcalay, Robin

Poster Session I Neighborhoods

P1.013 Feasibility and Safety of

Networks Mechanistically Link Alphasynuclein to Diverse Genetic Risk Factors for Parkinsonism —Vikram Khurana,

P1.004 Proteome-scale Molecular

Sunday, April 23  8:30 a.m.—5:30 p.m.

H

B

P1.251–328

P1.031–070 ePosters

P1.071–080

I

P1.329–412

a noninvasive biomarker for freezing of gait in Parkinson disease —Jesal Shah,

PARKINSON’S DISEASE: THERAPEUTICS AND TELEHEALTH I

P1.017 Efficacy of sublingual

apomorphine film (APL-130277) for the treatment of OFF episodes in patients with Parkinson’s disease: results from the Phase 3 study dose-titration phase —Robert Hauser, Stuart Isaacson,

Alberto Espay, Rajesh Pahwa, Daniel Truong, Eric Pappert, Peter Gardzinski, Bruce Dzyngel, Albert Agro, Hubert Fernandez

P1.018 Topiramate as an Adjunct to Amantadine in the Treatment of Dyskinesia in Parkinson’s Disease —

Christopher Goetz, Glenn Stebbins, Kathryn Chung, Anthony Nicholas, Robert Hauser, Mark Stacy, Kathleen Shannon

A

P1.001–030 A: Movement Disorders B: Research Methodology and Education; Practice, Policy, and Ethics; Movement Disorders ePosters C: Aging and Dementia D: Movement Disorders Poster Discussion E: Neuromuscular and Clinical Neurophysiology (EMG) F: General Neurology; Neuro-oncology; Headache; Pain and Palliative Care G: Epilepsy/Clinical Neurophysiology (EEG) H: Cerebrovascular Disease and Interventional Neurology; Infectious Disease I: MS and CNS Inflammatory Disease

P1.019 Identification of the Carbidopa Concentration in Subcutaneously Administered ND0612 (Levodopa/ Carbidopa) that Provides Optimal Levodopa Bioavailability —Liat Adar, Tami Rachmilewitz, Sheila Oren

P1.020 Duration of “on” periods after treatment with extended-release vs. immediate-release carbidopa-levodopa in patients with advanced Parkinson’s disease —William Ondo, Margery Mark, Nishit Modi, Sarita Khanna, Suneel Gupta

P1.021 Pooled Analysis of Phase

3 studies of ADS-5102 (amantadine hydrochloride) extended release capsules for Levodopa-Induced Dyskinesia: A detailed review of PD Home Diary Results —Caroline Tanner,

78 2017 AAN Annual Meeting Scientific Program

Rajesh Pahwa, Robert Hauser, Stuart Isaacson, Reed Johnson, Larissa Felt, Mary Jean Stempien

Isaacson, Alberto Espay, Rajesh Pahwa, Daniel Truong, Eric Pappert, Peter Gardzinski, Bruce Dzyngel, Albert Agro, Robert Hauser

P1.022 Rotigotine transdermal

P1.024 Effect of levodopa-carbidopa

Kawabe, Takanori Takazawa, Takehisa Hirayama, Masaru Yanagihashi, Ken Miura, Yuichi Ishikawa, Junya Ebina, Maya Kyuzen, Tetsuro Nagaoka, Masahiro Sawada, Sayori Hanashiro, Harumi Morioka, Yasuo Iwasaki

Poewe, David Standaert, Cindy Zadikoff, Stephanie Dubow, Lars Bergmann, Ashley Yegin, Coleen Hall, Vanessa Felipe, Weining Robieson, Luigi Barbato

patch attenuates freezing of gait during wearing off in patients with Parkinson’s disease —Ken Ikeda, Osamu Kano, Kiyokazu

P1.023 Disease severity does not predict effective ON-turning dose of apomorphine sublingual film (APL130277) in patient with Parkinson’s disease —Hubert Fernandez, Stuart

intestinal gel on dyskinesia: design of an open-label, randomized multicenter 12-week study in advanced Parkinson’s disease patients —Angelo Antonini, Werner

P1.025 ND0612—a Newly

Developed Liquid Levodopa/Carbidopa Formulation Administered Continuously Subcutaneously by a Mini-pump—


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