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Laboratory Equipment Guide us.panasonic-healthcare.com

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Discovery starts with a dream. A dream to know who we are. A dream to better our lives...

Behind every great discovery, there’s the technology that made it all possible.

Working as a scientist is challenging. No easy solutions, no guarantees.

That is why we believe having reliable technology is so important.

Spend less time worrying about your equipment. More time getting results.

Your life’s work is important so why settle for less. Here at Panasonic, we value reliability, efficiency, and innovation, so that every product we design ‘ is engineered to deliver precision.

Make your next discovery.

Ultra-low and Cryogenic Freezers Find the right freezer for your needs Twin Guard Series Freezers (-86ºC) ®

VIP® Series Freezers (-86ºC) PRO Series Freezers (-86ºC) Cryogenic Freezers (-150ºC) Chest Freezers (-86ºC /-80ºC)

8 13 18 27 30 32

Refrigerators & Freezers Ideal equipment for your refrigeration needs Feature Matrix Feature Overview Biomedical Freezers Biomedical Refrigerators with Freezers Laboratory Refrigerators Pharmaceutical Refrigerators Blood Bank Refrigerators Undercounter Refrigerators and Freezers

36 38 40 42 44 46 49 52 54

Table of Contents

Incubators Which incubator is best for you?

Features Overview CellIQ CO2 Incubator (5.8 cu.ft.)

TM

CellIQ Multigas (6.0 cu.ft.)

TM

CytoGROW Optimal CO2 Incubators (6.0 & 7.6 cu.ft.)

CytoGROW Compact CO2 & Multigas Incubator (1.7 cu.ft.)

CytoGROW ReachIn CO2 Incubators (30.1 cu.ft.)

Heated & Refrigerated Incubators Plant Growth Chamber CPWS (Cell Processing Work Station)

58 60 68 77 83 87 89 93 97 99

Autoclaves Top-Loading Portable Autoclaves

105

Monitoring LabAlertTM

107

Additional Services Service and Technical support Validation Service

109 110

INCUBATION TIMELINE

INNOVATION TIMELINE For over forty years Panasonic Healthcare has established a reputation as a premier manufacturer of precision biomedical and laboratory equipment.

REFRIGERATION TIMELINE

1969

1966

The first incubator launched.

Pharmaceutical refrigerators

1975

1984 Water jacketed CO2 incubator, MCO-165

1979 Blood Bank Refrigerator, MBR-390

2000 Introduction of inCu-saFe Active Background contamination control in CO2 incubators

®

2002 1977 -86°C ULT freezer, MDF-230 -30°C medical freezer, MDF-390

1980 -86°C upright ULT Freezer, MDF-380 Prefab refrigerator, MCU-1000 Cooling unit, MCU-5020

Introduction of SafeCell revolutionary UV decontamination in CO2 incubators

1981 Compact blood bank refrigerator, MBR-510/1010

1982 Large pharmaceutical refrigerators, MPR-510/1010

1993 2009 Introduction of CellIQ Series CO2 incubator, with H2O2 decontamination TM

1983 Compact -86°C ULT freezer, MDF-190

Pharmaceutical refrigerators, MPR 110/210 Cooled incubator, MIR-150/250/550

Four-door pharmaceutical refrigerator with -30°C freezer, MPR-411F/411FR

1998 Pharmaceutical refrigerator, MPR-512/1012 ISO 14001 (environmental recognition)

2014 Introduction of the CellIQ CO2 Incubator with Touch screen TM

1989 -86°C double-door upright ULT freezer, MDF-U581 Establishment of bio-soft laboratory, Tokyo plant

1997 -135°C ULT freezer, MDF-2135

Vertical Component Integration

2003

As a leader in consumer electronics, refrigeration, energy, and environmental products, Panasonic offers a robust source of proven technologies through a range of biomedical and medical research products.

-86°C VIP® freezers, MDF-U32V/U54VC

2010 A

B

Introduction of Twin Guard® Series -86°C ULT Freezer, MDF-U500VXC

2011 PRO Series Twin Guard® Series MDF-700VXC

Pioneering developments are applied to all Panasonic products through the precise model of Vertical Component Integration. Because many of our key component parts are designed and built by Panasonic, we offer the best and accurately matched components in each Panasonic product.

Panasonic draws on vast corporate resources to develop laboratory products that meet the needs of contemporary medical and scientific research.

The Panasonic philosophy of Vertical Component Integration is therefore, embodied through more human-oriented and easy-to-use ergonomic products.

Feature Matrix

SAVE

Core Technologies Panasonic core technologies, patents, and intellectual properties are represented in every product line. Core technologies apply to critical components and processes such as refrigeration compressors, microprocessor electronics, and patented VIP速 vacuum insulation panels. These are engineered to exact specifications for important applications in the life science, pharmaceutical, biotechnology, clinical, and industrial laboratories.

As a result, Panasonic products operate with dependability, safety, energy efficiency, and ergonomic sensitivity. Look for these with other proprietary technologies and patents on Panasonic laboratory products.

Cascade Cooling System

Precise Uniformity

Quiet, Reliable Compressors

Temperature Stability

Air Filter

Alarms & Monitoring

Rechargeable Battery

Condensation Management System

Service

Touch Screen

Energy Savings

IR

IR2 CO 2 Sensor

CFC-Free

InCu-saFe速 Technology

Optimum Footprint

H2O 2 Decontamination

Dual Compressor System

SafeCell UV

Filter-less Design

Active Background Control

Power Failure Alarm

Zirconia O 2 Sensors

Automatic Alarm System

Direct Heat & Air Jacket System

Remote Alarm

LCD Digital Display CPU and Touch Pad Insulated Inner Doors VIP 速 Vacuum Insulation Panel Cycle Defrost

Ergonomic Design

30%

2x protection

Ultra-low and Cryogenic Freezers

6

Filter-less Design

Cascade Cooling System

LCD Digital Display

Dual Compressor System

Quiet, Reliable Compressors

CPU and Touch Pad

Automatic Alarm System

Air Filter

Insulated Inner Doors

CFC-Free

Remote Alarm

Rechargeable Battery

VIP 速 Vacuum Insulation Panel

Optimum Footprint

Service

SAVE

Energy Savings

The Industry’s Most Complete Ultra-Low Storage Solution Table of Contents Find the right freezer for your needs.

What to look for in an ULT freezer?

8

11

Panasonic Ultra-low and Cryogenic Freezers Find the right freezer for your needs

8

Twin Guard® Series (-86ºC)

13

VIP® Series Freezers (-86ºC)

18

PRO Series Freezers (-86ºC)

27

Cryogenic Freezers (-150ºC)

30

Chest Freezers (-86ºC /-80ºC)

32

7

Find the right freezer

Twin Guard Series

VIP Series

-86ºC Ultra-low Freezers

-86ºC Ultra-low Freezers

®

MDF-U700VXC-PA, MDF-U500VXC-PA

SAVE

Two independent systems offering double security for your samples.

8

®

MDF-U76VA-PA, MDF-U76VC-PA, MDF-56VC-PA MDF-U53VA-PA, MDF-U33V-PA

SAVE

Most reliable freezer with best performance and maximum energy savings.

Panasonic Healthcare Corporation of North America | Ultra-Low and Cryogenic Freezers

for your needs.

PRO Series

Chest Freezers

Cryogenic Freezer

-86ยบC Ultra-low Freezers

-86ยบC /-80ยบC Ultra-low Freezers

-150ยบC Ultra-low Freezers

MDF-U5486SC-PA, MDF-U7486SC-PA

Optimum performance under optimum budget.

MDF-594C-PA, MDF-794C-PA MDF-C8V1-PA

Energy efficiency and high performance cooling with space saving design.

MDF-C2156VANC-PA

Reliable mechanical refrigeration with maximum storage capacity.

9

Surpasses the customer preference of +/- 5°C*

+/-5 UNIFORMITY

0°C

Uniformity & Reliability

Panasonic products incorporate the latest applied theories and ideas, refrigeration compressors, electronic components, robotic manufacturing, and economies-ofscale that directly benefit the customer. Furthermore, Panasonic products are extensively tested to meet the toughest quality standards in the world for performance, ergonomics, and cost of ownership. Through the vigorous application of our unique Vertical Component Integration, Panasonic products offer tangible benefits from performance and reliability to ergonomics and convenience -that no other manufacturer can provide. * Based on internal validation data tested at -80°C setpoint,in an empty chamber with 23°C ambient temperature.

+/-5

Performance

Panasonic Ultra-low freezers offer the following advantages: Rapid “pull down” – the time needed for your freezer to return to set point after door openings and maintain sample integrity.

Best temperature uniformity that ensures all samples are well protected.

Brand B Brand A Panasonic

MORE EFFICIENT

30%

10

Pull down speed from room temp to -80°C .

HRs

Panasonic Healthcare Corporation of North America | Ultra-Low and Cryogenic Freezers

What to look for in an ULT Freezer?

Panasonic products are extensively tested to meet the toughest quality standards in the world for performance, ergonomics, and cost of ownership. $

Energy Efficiency

Panasonic ultra-low freezers are insulated with highperformance CFC-free insulation, and new composite techniques to minimize energy consumption and lower operating costs. Beyond highly competitive first costs, Panasonic ultra-low freezers demonstrate the lowest operating costs per cu.ft. (liter) in the worldwide market.

Consumed Power (kWh/day)

Brand A

30%

30% Faster

faster

Panasonic

Brand B 9

6

10 15 20 25

3

0

(Hours) 0 5

Superior Footprint Stainless steel shelf and insulated inner door combinations create choices of interior compartments that can be arranged for long-term, low access biologicals or short-term, frequently accessed material.

11

Twin Guard® Series (-86ºC ) MODEL

TEMPERATURE RANGE

INTERIOR VOLUME

MDF-U500VXC-PA

-50ºC to -86ºC

MDF-U700VXC-PA

-50ºC to -86ºC

AREA FOOTPRINT (NOMINAL)

INSULATION TYPE

STORAGE (2"/ 51 MM BOXES)

STORAGE (3"/76 MM BOXES)

STORAGE (2ML VIALS IN BOXES)

ELECTRICAL, 60HZ

18.3 cu.ft.

519 L

8.37 sq.ft.

0.67 m2

VIP® PLUS

352

224

35,200

208/230V NEMA 6-15

25.7 cu.ft.

728 L

9.51 sq.ft.

0.88 m2

VIP® PLUS

576

384

57,600

208/230V NEMA 6-15

VIP® Series (-86ºC ) MODEL

INTERIOR VOLUME

EXTERIOR DIMENSIONS (W X F-B X H)

AREA FOOTPRINT, NOMINAL

INSULATION TYPE

FIBERBOARD BOXES, 2” HIGH (2ML) IN PANASONIC RACKS

SAMPLE VIALS, 2ML (2” BOX), 100-CELL DIVIDERS

ELECTRICAL, 60HZ

MDF-U33V-PA

11.8 cu.ft.

333 L

26.4” x 34.1” x 73.2” 670 x 870 x 1860 mm

6.25 sq.ft.

0.58 m2

VIP®

216

21,600

115V, AC, 15 amp

MDF-U53VA-PA

18.3 cu.ft.

519 L

30.3” x 34.4” x 78.3” 770 x 870 x 1990 mm

7.24 sq.ft.

0.67 m2

VIP®

352

35,200

115V, AC, 20 amp

MDF-U56VC-PA

18.6 cu.ft.

526 L

30.3” x 34.4” x 78.3” 770 x 870 x 1990 mm

7.24 sq.ft.

0.67 m2

VIP® PLUS

384

38,400

208/230V, AC, 15 amp

MDF-U76VC-PA

25.7 cu.ft.

728 L

39.8” x 34.4” x 78.3” 1010 x 870 x 1990 mm

9.51 sq.ft.

0.88 m2

VIP® PLUS

576

57,600

208/230V, AC, 15 amp

MDF-U76VA-PA

25.7 cu.ft.

728 L

39.8” x 34.4” x 78.3” 1010 x 870 x 1990 mm

9.51 sq.ft.

0.88 m2

VIP® PLUS

576

57,600

115V, AC, 20 amp

PRO Series (-86ºC ) VOLUME (CU.FT.)

EXTERIOR DIMENSIONS (W X F-B X H)

INSULATION TYPE

STORAGE (2"/ 51 MM BOXES)

STORAGE (3"/76 MM BOXES)

STORAGE (2ML VIALS IN BOXES)

VOLTAGE, POWER CONNECTION

MDF-U5486SC-PA

17.1 483 L

35.0" x 34.4" x 78.3" 890 x 840 x 1990 mm

Conventional

320

192

32,000

208/230V NEMA 6-15

MDF-U7486SC-PA

23.5 668 L

44.5" x 34.4" x 78.3" 1130 x 870 x 1990 mm

Conventional

480

288

48,660

208/230V NEMA 6-15

MODEL

Cryogenic Freezer ( -150ºC ) MODEL

MDF-C2156VANC-PA

VOLUME

EXTERIOR DIMENSIONS

(CU.FT.)

(W X F-B X H)

8.2 231 L

68.1" x 30.1" x 39.8" 1730 x 765 x 1010 mm

INSULATION TYPE

STORAGE

STORAGE

STORAGE

(2"/ 51 MM BOXES)

(3" / 76 MM BOXES)

(2ML VIALS IN BOXES)

VIP® PLUS

150

105

15,000

VOLTAGE, POWER CONNECTION 208/230V NEMA 6-15

Chest Freezers (-86ºC / -80ºC )

12

INSULATION TYPE

TEMPERATURE

STORAGE

STORAGE

STORAGE

(°C)

(2"/51 MM BOXES)

(3"/76 MM BOXES)

(2ML VIALS IN BOXES)

21.6" x 27.0" x 37.2" 550 x 685 x 945 mm

VIP® PLUS

-80°C

42

30

4,200

115V NEMA 5-15

17.2 487 L

79.1" x 30.3" x 42.1" 2010 x 770 x 1070 mm

Conventional

-86°C

351

243

35,100

208/230V NEMA 6-15

24.8 701 L

101.2" x 30.3" x 42.1" 2570 x 770 x 1070 mm

Conventional

-86°C

507

351

50,700

208/230V NEMA 6-15

VOLUME

EXTERIOR DIMENSIONS

(CU.FT.)

(W X F-B X H)

MDF-C8V1-PA

3.0 84 L

MDF-594C-PA MDF-794C-PA

MODEL

VOLTAGE, POWER CONNECTION

TwinGuard

®

EXPERIENCE TWICE THE SECURITY

30% more

2x Protection

VIP® Insulation

Simply secure.

Give your samples the ultimate protection of patented Twin Guard® technology – two independent systems can individually sustain ultra-low temperatures in the event of a failure, so you can rest easy knowing your valuable work is in good hands.

Learn more at us.panasonic-healthcare.com/twinguard

The Panasonic Twin Guard® Series satisfies the industry demand for safe, long-term storage for the most high-valued materials. Two independent refrigeration systems, combined with optional liquid nitrogen or liquid CO2 back-up systems, offer a circle of protection unmatched in the marketplace.

Developed for use with conventional inventory racks and boxes, the Twin Guard® Series is ideal for storage of sensitive stem cells, embryos, cell lines, and other rare specimens.

CRITICAL

-65ºC

B

-86ºC A

Ultimate Protection Temperature

Give your samples the ultimate protection of patented Twin Guard® technology – two independent systems can individually sustain ultra-low temperatures in the event of a failure, so you can rest easy knowing your valuable work is in good hands.

23ºC TRADITIONAL A

CRITICAL

LOST

Time

ULTRA-LOW

TWIN GUARD® SERIES

ULTRA-LOW

Temperature

LOST

The Most Reliable Ultra-Low Freezers for Long-Term Storage

-86ºC

Freezer Failure A Time

The efficient ultra-low cooling is achieved through two independent evaporator circuits surrounding the interior chamber.

Performance & Recovery 40 20

0

Pull-up while a power failure

-20 -40

Single compressor operation (kept at approx. -65°C or lower depending on load)

-60 -80 -100

Normal cycle operation (-80°C setting)

0

1

2

3 4

5

6

7

8 9 10 11 12

Chamber temp. (°C)

Chamber temp. (°C)

20

Central air temp. in cabinet Ambient temp. 30°C, No-Load

0 -20 -40 -60 -80 -100

0

1

2

3 4

5

6

7

8 9 10 11 12

(hour)

(hour) Pull-up characteristics during power failure Pull-down charateristics

14

Panasonic Healthcare Corporation of North America | Ultra-Low and Cryogenic Freezers

Twin Guard® Technology The Panasonic MDF-U500VXC-PA and MDF-U700VXC-PA Twin Guard® Series ultra-low freezers are designed for -86°C storage of high-value biological samples. Ideal for critical material storage in repositories, highly secure BSL 3/4 labs, GMP facilities, hospitals, clinics, and medical research facilities. The Twin Guard® Series introduces the concept of two independent auto-cascade refrigeration systems within a single cabinet.

Barrier Film VIP® PLUS Interior Rigid foamed polyurethane

4

1

11 9 A vacuum relief valve is mounted in the left wall.

2

The Panasonic ergonomic design features a high-security Easy-In / Easy-Out door latch designed for simplicity and safety. Also allows for one handed operation.

3

12 7 10 5

8

6

1.

Panasonic patented VIP® PLUS vacuum insulation panel cabinet construction for high insulating value and increased interior volume in the same footprint.

2.

Easy-In/Easy-Out door latch for smooth, onehanded operation, positive seal against gasket.

3.

Integrated, microprocessor-based control system and LCD display information center includes comprehensive set-point, alarm, monitoring, diagnostic and communications functions.

4.

Insulated, sealed, and gasketed inner doors seal inside to offer additional protection, improve uniformity.

5.

New air-cooled super condenser energy transfer technology maintains optimum condenser air flow and eliminates the need for an air filter or reducing the requirement for periodic maintenance.

9.

6.

High impact, recessed casters and leveling feet simplify installation.

11. A vacuum relief valve is mounted in the left wall

7.

Cool Safe compressors are specifically designed for one-compressor, autocascade applications.

8.

Twin Guard® Series redundant refrigeration -86° Dual Cool circuits offer two systems in one, each providing back-up for the other, or working together for fast recovery or energy savings

Multiple access ports permit insertion of independent probes, instrumentation or liquid nitrogen or liquid CO2 back-up injectors.

10. HFC-refrigerants are highly efficient,

environmentally safe, non-ozone depleting. to ensure easy access to chamber following door closure.

12. Standard remote alarm contacts and optional communication port available.

15

Optimal Capacity & Footprint Panasonic Twin Guard® series freezers offer a large storage capacity of 576 2” boxes, while maintaining a small footprint with reduced energy usage. This leads to a lower energy requirement per box stored, saving you money in ongoing operational costs.

TEMPERATURE RANGE

MODEL NUMBER

INTERIOR VOLUME

AREA FOOTPRINT (NOMINAL)

STORAGE

STORAGE

STORAGE

(2"/ 51 MM BOXES)

(3"/76 MM BOXES)

(2ML VIALS IN BOXES)

ELECTRICAL, 60HZ

MDF-U500VXC-PA

-50ºC to -86ºC

18.3 cu.ft.

519 L

8.37 sq.ft.

0.67 m2

352

224

35,200

208/230V NEMA 6-15

MDF-U700VXC-PA

-50ºC to -86ºC

25.7 cu.ft.

728 L

9.51 sq.ft.

0.88 m2

576

384

57,600

208/230V NEMA 6-15

Technical Specifications MODEL NUMBER

MDF-U500VXC-PA

MDF-U700VXC-PA -50°C to -86°C

TEMPERATURE SET-POINT RANGE DESIGN COOLING PERFORMANCE -86 DUAL°COOL (BOTH COMPRESSORS)

-86°C (ambient temperature 30°C)

SINGLE SYSTEM COOLING PERFORMANCE (INDEFINITE)

-65°C (ambient temperature 30°C)

CABINET DESIGN AND CONSTRUCTION

Patented VIP® PLUS composite wall

CABINET INSULATION EXTERIOR DIMENSIONS (W X F-B X H)

35.5” x 40” x 78.3” 770 x 870 x 1990 mm

42.5” x 40” x 79.1” 1010 x 870 x 2010 mm

INTERIOR DIMENSIONS (W X F-B X H)

25.6” x 23.6” x 54.3” 630 x 600 x 1380 mm

34.3” x 23.6” x 55.1” 870 x 600 x 1400 mm

18.3 cu.ft.

519 liters

25.7 cu.ft.

728 liters

VOLUME SHELVES ACCESS PORT VACUUM RELEASE PORT

3, adjustable, stainless steel (4 compartments) Diameter = 0.5”/17mm; 3 locations Standard, Manual

REFRIGERATION SYSTEM REFRIGERATION TECHNIQUE COMPRESSORS

Panasonic -86 Dual°Cool independent, redundant cooling systems with automatic switchover Per system: Single, hermetically-sealed 1100W Panasonic Cool Safe compressor, air-cooled

REFRIGERANT

Environmentally safe HFC refrigerant

AIR EXCHANGE

Dual condenser fans with particulate trap; no filters are required

CYCLE OPTIONS

Standard or energy-saving EcoMode operation

CONTROLS, ALARM, MONITORING CONTROLLER DATA MANAGEMENT COMMUNICATIONS ALARMS REMOTE ALARM CONTACTS ELECTRICAL

16

Panasonic microprocessor-based, door-mounted control with graphical LCD information center Internal data log with log file memory Data can be transmitted via RS485, optional 4-20 mA High/Low temperature, door ajar, power failure, remote alarm contact, part replacement notification, fan motor lock, individual cooling circuit check Standard; normally open or normally closed, dry contacts 208V-230V, AC, 60Hz, 1 phase, NEMA 6-15, 15 amp separate breaker recommended

Security, Control & Monitoring Pop-up menu

Positive feedback tactile entry and function keys

Visual alarm indicator

Digital LCD display with alphanumeric information Message display

Menu call button Buzzer silence

Display contrast adjustment

Audible alarm

Positive feedback tactile input buttons

All performance attributes

Out-of-compliance events are announced by visual and audible warnings. Error codes quickly identify problem sources and permit fast diagnosis and remediation.

are displayed on a large, visually intuitive alphanumeric display.

Internal temperature log files are expressed in graphical form over time.

ECO MODE operation image Pull down

Stable temperature

NORMAL

Eco Mode vs. Normal Mode

Temp.

Chamber temp

T12 on

T12 off

Comp A Comp B

2 compressors are turned ON/OFF at same time

NORMAL mode operation image Pull down

Stable temperature

Temp.

Comp A Comp B

This chart shows the repeatable cycling wave form of normal mode vs. eco mode.

Normal mode is for strict GMP applications.

ECO MODE

Comp A Comp B

Chamber temp T on

T1 off

T12 on

T2 off

T1 2 on

Comp A Comp B

Chamber temp T12 on

Comp A Comp B

T12 off T2 on

T2 off

2 compressors and fan motor for each are independently controlled by SV and read AT.

17

VIP PLUS Freezers ®

ULTIMATE SAMPLE STORAGE

up to 31% more ENERGY EFFICIENT

+

/- 5°C

UNIFORMITY

Innovative Design HIGH EFFICIENCY HEAT EXCHANGER

Reliability at its finest.

With >99% reliability rate, VIP freezers provide your samples with energy efficient and high performance ultra low storage. The patented VIP® PLUS insulation panel ensures superior temperature uniformity for the ultimate protection your samples deserve.

Panasonic Healthcare Corporation of North America | Ultra-Low and Cryogenic Freezers

What makes VIP Freezers so Reliable? ®

Panasonic VIP® ultra-low freezers represent the industry’s most complete combination of refrigeration, control, alarm, monitoring, and accessibility for product safety at -86°C. Ideal for material storage in repositories, hospitals, clinics, and medical research facilities, the VIP® Series freezers are designed to reduce energy consumption and offer optimal performance.

+5°C

Up to 31% more efficient

Panasonic

* Based on internal validation data tested at -80°C setpoint, in an empty chamber with 23°C ambient temperature.

30%

Panasonic

Faster

Brand A

Brand B

0

3

6

25 20 15 10 5 0

Brand B

Validated Temperature Recovery Increased reserve cooling capacity improves temperature recovery after door openings.

Uniformity

-5°C

Panasonic compressors employs a unique orientation of components that increases compressor longevity and refrigeration capacity while reducing operating pressure and discharge temperatures – a key component that yields better reliability.

Brand A

Surpasses the customer preference of +/- 5°C*

Energy Savings

Panasonic

Combination of patented VIP® plus vacuum insulation panel with Panasonic designed compressors specific to ultralow applications, result in unmatched uniformity, that surpasses the strictest protocols, no matter where your samples are stored within the unit.

Performance

Consumed Power (kWh/day)

Uniformity you can trust

Energy Efficient Cascade Cooling Panasonic cascade refrigeration system and the new improvements in the heat exchanger design drastically increase the efficiency of the entire system. The end result is less energy consumption, while improving the overall efficiency and reliability of the freezer.

9

(HRs) * The data may vary depending on the use, circumstances and optional accessories.

Validation documents can be provided for each serial number with an additional fee.

19

VIP® Series -86°C Freezer Energy Efficient Cascade Cooling System NEW! High Efficiency Heat Exchanger

Main Condenser and Motor/Fan Assembly

Low stage capillary tube heat exchanger provides optimum heat transfer between high and low temperature points in the low stage leading to greater energy efficiency.

Panasonic’s exclusive triple pass forced air condenser increases overall system efficiency by providing maximum surface area for heat rejection.

Low Stage Refrigerant Commonly available worldwide, R508. Industry Standard.

High Stage Refrigerant Commonly available worldwide.

Selected for optimum cooling performance in compliance with international environmental protection laws.

Low Stage Compressor Compresses and pumps refrigerant through the low stage circuit.

Oil Heat Exchanger Panasonic exclusive high stage refrigerant passes through both compressor oil sumps to cool lubricating oil resulting in high-stage refrigerant being used to increase the durability of the compressors.

20

Instrumentation (Not Shown) Temperature and pressure sensors throughout the high and low stage circuits transmit information to the Panasonic ‘Status Alert’ central controller for operation, monitoring, interpretation and component protection.

Panasonic Healthcare Corporation of North America | Ultra-Low and Cryogenic Freezers

VIPÂŽ Features 1.

asy-In/Easy-Out door latch for smooth, oneE handed operation, positive seal against gasket.

Padlock provision standard.

2.

Integrated, microprocessor-based control system and LED display includes comprehensive set-point, alarm, monitoring, diagnostic and communications functions.

3.

Insulated and gasketed inner doors seal inside to offer additional protection and improve uniformity. Inner door latches are standard.

Doors can be easily removed for defrosting.

4.

ront access to washable, electrostatic F condenser filter for routine condenser air filter cleaning.

5.

igh impact, recessed casters and leveling feet H simplify installation.

6.

New generation Panasonic designed Cool Safe compressors are specifically designed for low temperature applications.

7.

ultiple access ports permit insertion of M independent probes, instrumentation or liquid N2 or liquid CO2 back-up injectors.

8.

ommercially available HFC-refrigerants are C highly efficient, environmentally safe and nonozone depleting.

9.

emote alarm contacts and optional R communication port available; see Accessories.

10. Vacuum relief valve (Available on the MDF-U56VC-PA, MDF-U76VC-PA, and MDF-U76VA-PA)

2

10

3

7

1

4 9 5

8

6

Optional Accessories

The Panasonic ergonomic design features a high-security Easy-In/ Easy-Out door latch designed for simplicity and safety. Also allows for one handed operation.

Inventory Rack Systems

LabAlertTM Monitoring System

The Digital Temperature Recorder

Panasonic freezers are available with a variety of inventory racks to meet specific applications. Freezers can be ordered with full-load inventory systems by selecting one catalog number.

Complete your preservation requirements with Panasonic LabAlertTM Monitoring solution.

LabAlertTM makes the monitoring of your freezer easier than ever. You can keep a constant check on the temperature, pressure, door status, and refrigerant leaks that your samples are exposed to– anytime, anywhere. Easy set up, affordable pricing, infinite scalability, and intuitive user interface.

The recorder mounts on the cabinet door and is programmable to capture and store non-corrutible data points for downloading to an independent data management system to meet criteria outlined in U.S. FDA 21CFR Part II directives. An independent probe is placed in the interior chamber.

Circular Recorder, Strip Chart Recorder and Recorder Mounting Bracket

CO2 Backup System and LN2 Backup System

21

Operating Analysis The superior energy efficiency of Panasonic VIP® Series Ultra-Low Freezers leads to significant annual cost savings.

Lower kW usage combined with lower heat rejection leads to savings on freezer operation costs plus associated HVAC costs to remove the heat generated by the freezer. With an industry-leading capacity of up to 576 2” boxes, the energysaving advantages of this efficient Panasonic system extend to lower per-unit storage costs regardless of the preferred inventory configuration.

The concept of High Density Storage is enabled by advances in Panasonic Cool Safe compressor design. The cost per 2” box of interior storage space is significantly lower in a Panasonic ultra-low freezer, generating immediate return on investment based on initial costs, operating costs, and maintenance costs over time.

$ Savings - Per Unit

2500

31.1%

30 25 20 15 10 5 0

Operating Cost Savings per Unit - 1/5/10 Years Panasonic MDF-U76VC vs. Brand A and B

21%

% Savings –Panasonic MDF-U76VC

Operating Cost Savings Percentage

2000

YEAR 1

YEAR 2 $1241

1500 1000 500

$730 $146

Panasonic

MDF-U76VC-PA

Brand A Brand B

$248

0

Up to 31% less cost annually

Total Operating Cost of 1 Unit

YEAR 1

YEAR 2

YEAR 3

YEAR 4

YEAR 5

Dollars

4000 $2737

2000 1000 0

22

$3467

3000

$547 $693

$795

$3978

Panasonic Healthcare Corporation of North America | Ultra-Low and Cryogenic Freezers

Optional Accessories WATER COOLED CONDENSER

DESCRIPTION

WATER PRESSURE & TEMPERATURE

Maximum Water Pressure: 150psig, Minimum Water Pressure Differential: 15psig, Maximum Water Temperature: 30°C

CONNECTIONS

Typically ½” compression fittings on inlet and outlet but can be customized for customer needs

REQUIRED WATER FLOW RATE (MAXIMUM)

Tower Water: 11.4 liters per minute Qualified technician required at time of installation to balance water flow requirements.

Efficiencies can be easily obtained regarding water usage by balancing the water flow to optimum usage and freezer efficiency dependent upon the specific site installation

INSTALLATION

DESCRIPTION

ACCESSORY

Set of two; Field Installed; replaces half inner door; for a four-door configuration order two sets

HALF INNER DOOR DIGITAL TEMPERATURE RECORDER

MDF-5ID-PW (MDF-U53VA), MDF-5ID1-PW (MDFU-56VC), MDF-7ID1-PW (MDF-U76VC / MDF-U76VA)

Auxiliary Data Logger

HAMSTERDT2

LIQUID CO2 BACK-UP SYSTEM

Auxiliary back-up in event of power failure

CVK-UB2(I)-PW

LIQUID N2 BACK-UP SYSTEM

Auxiliary back-up in event of power failure

CVK-UBN2-PW

CHART RECORDER

Circular Chart Temperature Recorder, 7 Day

MTR-C954

CHART PAPER

6” Diameter, 7 Day Chart

C7100386REV

REPLACEMENT PEN, RED / BLUE

Felt tip pens, 6 per pack

R252 / R253

DIGITAL TOUCH PANEL RECORDER

Programmable digital temperature recorder

FT560SN

DATA LOGGING SOFTWARE

For use with touch panel recorder

A016

21 CFR PART 11 COMPLIANT SOFTWARE

For use with touch panel recorder

A026

Energy Performace Panasonic VIP® freezers provide reduced operational cost for highly efficient sample storage.

Panasonic freezers emit less heat into the laboratory, minimizing air conditioning costs.

VIP® freezers help the environment by reducing carbon footprint.

Power Consumption By Capacity (KW/day/box capacity)

Total annual operating cost for operation and cooling by capacity

Annual CO2 Emissions

by Box Capacity

0$

Up to 39% more efficient

Up to 40% less cost

Panasonic freezers provide reduced operational cost for highly efficient sample storage.*

Cost is an average for operating freezer including cost to remove heat from the room generated by the freezer.

Panasonic

Brand A

3 2 1 0

4.33

$1

4

4.97

$2

5

2.99

$3

3.04

.043

0

.038

.01

.026

.02

$4

2.64

.03

$5

1.83

.04

Pounds / Box Capacity

Less Emission

Dollars / Box Capacity

Operating Cost

KW / day / box capacity

More Efficient

Up to 40% lower emissions

Brand B

23

Sample Security, Alarms & Monitoring The Panasonic microprocessor control system is secure, easy-to-use, and comprehensive. Set-point, alarm parameters, and selfdiagnostic functions are accessed through a tamper-resistant keypad protocol. Control inputs are managed with convenient push buttons on a unitized, sealed control overlay. The panel is door-mounted and angled for easy access.

Panasonic exclusive NiMH battery powers control memory and alarm functions during power failure.

Status alert function uses predictive intelligence to determine if freezer is operating within specifications under existing environmental conditions.

Digital display defaults to actual chamber temperature.

Display mode changes when set-point, alarm parameters, programming, and diagnostic functions are performed.

Alarm indicator lamp glows when freezer is in alarm condition. Alarm ringback is factory set for 30 minutes, adjustable in 10 minute increments from 10 to 60 minutes.

Filter indicator lamp glows, when electrostatic filter requires removal for cleaning.

Door alarm indicator has 2 minute delay until audible alarm activates. Delay time is adjustable.

Set-point entry advances digital to next value from 0 to 9.

Buzzer silence temporarily mutes audible alarm.

Alarm test verifies readiness of alarm function and Ni-MH battery charge.

Adjustable alarm set-points are factory set 10ยบC above and below set-point.

Alarm parameters are adjustable by pressing up or down arrow keys and following the prompt.

24

Set-point entry advances digital display to next position.

Press to set temperature; set button is also used for other diagnostic functions.

Panasonic Healthcare Corporation of North America | Ultra-Low and Cryogenic Freezers

Optimal Capacity & Footprint The concept of High Density Storage is enabled by advances in Panasonic Cool Safe compressor design. The cost per 2” box of interior storage space is significantly lower in a Panasonic VIP® ultra-low freezer, generating immediate return on investment based on initial costs, operating costs, and maintenance costs over time.

MODEL NUMBER

MDF-U33V-PA

MDF-U53VA-PA

MDF-U56VC-PA

MDF-U76VC-PA

MDF-U76VA-PA

3 Columns 4 Rows

4 Columns 4 Rows

4 Columns 4 Rows

6 Columns 4 Rows

6 Columns 4 Rows

RACK POSITIONS, STANDARD CONFIGURATION

FIBERBOARD BOXES, 2” HIGH (2ML) IN RACKS SAMPLE VIALS, 2ML (2” BOX), 100-CELL DIVIDERS FIBERBOARD BOXES, 3” HIGH (4ML) IN RACKS SAMPLE VIALS, 4ML (3” BOX), 100-CELL DIVIDERS

216

352

384

576

576

21,600

35,200

38,400

57,600

57,600

144

224

256

360

384

14,400

22,400

25,600

38,400

38,400

STANDARD MICROPLATE WITH FOIL TAPE, IN RACKS

1,298

2,112

2,112

3,456

3,456

STANDARD MICROPLATE WITH COVER LID, IN RACKS

1,008

1,632

1,632

2,596

2,596

MAXIMUM VIAL CAPACITY INCLUDES FULL QUANTITY OF STORAGE RACKS, BOXES AND DIVIDERS

FULLY LOADED INVENTORY SYSTEMS SLIDING DRAWER INVENTORY RACKS 2” HIGH BOXES (2ML SAMPLE) 100-CELL DIVIDER

(6) GRD442A (6) GRD452SS

(8) GRD462SS (8) GRD452SS

(8) GRD443A (8) GRD452SS

(24) GRD462SS

(24) GRD462SS

SLIDING DRAWER INVENTORY RACKS, 3” HIGH BOXES (4ML SAMPLE) 100-CELL DIVIDER

(12) GRD433A

(8) GRD443A (8) GRD433A

(8) GRD443A (8) GRD452SS

(18) GRD443A (6) GRD433A

(24) GRD443A

SLIDING DRAWER SAMPLE RACKS FOR FIBERBOARD STORAGE BOXES (BOXES NOT INCLUDED)

INDIVIDUAL STORAGE RACK SYSTEM SLIDING DRAWER RACK, FOR 2” HIGH (2ML SAMPLE) BOXES; HOLDS 6 BOXES HIGH X 4 BOXES DEEP

GRF462SS Capacity 8

SLIDING DRAWER RACK, FOR 2” HIGH (2ML SAMPLE) BOXES; HOLDS 5 BOXES HIGH X 4 BOXES DEEP

GRD452SS Capacity 6

SLIDING DRAWER RACK, FOR 2” HIGH (2ML SAMPLE) BOXES; HOLDS 4 BOXES HIGH X 4 BOXES DEEP

GRD442A Capacity 6

SLIDING DRAWER RACK, FOR 3” HIGH (4ML SAMPLE) BOXES; HOLDS 4 BOXES HIGH X 4 BOXES DEEP SLIDING DRAWER RACK, FOR 3” HIGH (4ML SAMPLE) BOXES; HOLDS 3 BOXES HIGH X 4 BOXES DEEP INDIVIDUAL STORAGE RACK SYSTEM

GRD433A Capacity 12

GRF462SS Capacity 24

GRF462SS Capacity 24

GRD443A Capacity 8

GRD443A Capacity 8

GRD443A Capacity 24

GRD443A Capacity 24

GRD433A Capacity 8

GRD433A Capacity 8

GRD452SS Capacity 8

STANDARD CELLULAR INVENTORY RACKS FOR FIBERBOARD STORAGE BOXES (BOXES NOT INCLUDED))

INVENTORY RACK FOR 2” (2ML SAMPLE) BOXES; 6 BOXES HIGH X 4 BOXES DEEP

GRF462SS Capacity 8

INVENTORY RACK FOR 2” (2ML SAMPLE) BOXES; 5 BOXES HIGH X 4 BOXES DEEP

GRF452SS Capacity 6

INVENTORY RACK FOR 2” (2ML SAMPLE) BOXES; 4 BOXES HIGH X 4 BOXES DEEP

GRF442A Capacity 6

INVENTORY RACK FOR 3” (4ML SAMPLE) BOXES; 4 BOXES HIGH X 4 BOXES DEEP INVENTORY RACK FOR 3” (4ML SAMPLE) BOXES; 3 BOXES HIGH X 4 BOXES DEEP

GRF462SS Capacity 16

GRF433A Capacity 12

GRF462SS Capacity 16

GRF462SS Capacity 24

GRF462SS Capacity 24

GRF443A Capacity 8

GRF443A Capacity 8

GRF443A Capacity 24

GRF443A Capacity 24

GRF433A Capacity 8

GRF433A Capacity 8

GRF452SS Capacity 8

25

Technical Specifications MODEL NUMBER

MDF-U33V-PA

MDF-U53VA-PA

MDF-U56VC-PA

MDF-U76VC-PA

MDF-U76VA-PA

INTERIOR VOLUME

11.8 cu.ft.

333 L

18.3 cu.ft.

519 L

18.6 cu.ft.

526 L

25.7 cu.ft.

728 L

25.7 cu.ft.

728 L

AREA FOOTPRINT, NOMINAL

6.25 sq.ft.

0.58 m2

7.24 sq.ft.

0.67 m2

7.24 sq.ft.

0.67 m2

9.51 sq.ft.

0.88 m2

9.51 sq.ft.

0.88 m2

115V, AC, 15 amp

115V, AC, 20 amp

208/230V, AC, 15 amp

208/230V, AC, 15 amp

115V, AC, 20 amp

ELECTRICAL, 60 HZ PATENTED VIP® CONSTRUCTION INSULATED INNER DOOR INNER DOOR CONFIGURATION

Steel-framed, high impact plastic with foam-in place insulation 2

2 (4 optional)

DOOR GASKETS

2 (4 optional)

2 (4 optional)

2 (4 optional)

Multi-point compression gaskets

CONDENSER FILTER, EASY CLEANING

Electrostatic filter standard, front accessible for easy access, no tools required

ROUNDED INTERIOR CORNERS

Simplify Cleaning

SHELF BRACKETS

Incrementally adjustable

CASTERS

High-impact 4 with leveling feet

SEISMIC RESTRAINTS

Standard; hard connection to facility wall

ACCESS PORTS

Multiple ports allow use of injection tubes, probes, leads, instrumentation

DIMENSIONS & WEIGHT INTERIOR (W X F-B X H)

19.3” x 23.6” x 44.9” 490 x 600 x 1140 mm

24.8” x 23.6” x 54.3” 630 x 600 x 1380 mm

24.8” x 23.6” x 55.1” 630 x 600 x 1400 mm

34.2” x 23.6” x 55.1” 870 x 600 x 1400 mm

34.2” x 23.6” x 55.1” 870 x 600 x 1400 mm

EXTERIOR (W X F-B X H)

26.4” x 34.1” x 73.2” 670 x 870 x 1860 mm

30.3” x 34.4” x 78.3” 770 x 870 x 1990 mm

30.3” x 34.4” x 78.3” 770 x 870 x 1990 mm

39.8” x 34.4” x 78.3” 1010 x 870 x 1990 mm

39.8” x 34.4” x 78.3” 1010 x 870 x 1990 mm

562 lbs 255 kg

660 lbs 290 kg

672 lbs 305 kg

805 lbs 365 kg

820 lbs 373 kg

NET WEIGHT, EMPTY

REFRIGERATION SYSTEM, HFC REFRIGERANTS, PANASONIC COOL SAFE HIGH PERFORMANCE COMPRESSORS HIGH STAGE

1 HP

½ HP

1 HP

1 HP

1 HP

LOW STAGE

¾ HP

1 HP

1½ HP

1½ HP

1½ HP

Not Available

Not Available

Standard

Standard

Not Applicable

Standard

Standard

Standard

Standard

Standard

VOLTAGE BOOSTER, BUILT-IN SOUND ABATEMENT

REFRIGERATION SYSTEM, HFC REFRIGERANTS, PANASONIC COOL SAFE HIGH PERFORMANCE COMPRESSORS POWER, AC, 1 PHASE RECOMMENDED BREAKER, DEDICATED NEMA PLUG / RECEPTACLE

26

115V

115V

208-230V

208-230V

115V

15 amp

20 amp

15 amp

15 amp

20 amp

5-15P/5-15R

5-20P/5-20R

6-15P/6-15R

6-15P/6-15R

5-20P/5-20R

PRO Series Insulated for Reduced Carbon Footprint.

What makes PRO Series freezers so efficient?

Models: MDF-U7486SC-PA, MDF-U5486SC-PA

SAVE

Think Green: Environmentally friendly refrigerants, RoHS compliant and low-noise operation.

PRO Series -86°C Freezer Performance Advantages Panasonic’s conventionally insulated PRO Series ultra-low freezers provide energy savings while minimizing carbon footprint throughout the laboratory without compromising performance. It also maintains the internal temperatures as low as -86°C. All models use Panasonic-designed compressors for ultra-low temperature applications. Manufactured with foam-in-place insulation to maximize interior temperature uniformity, they are ideally suited for use in hospitals and laboratories for long-term preservation and storage of specimens and components, as well as material testing.

The Panasonic ergonomic design features a high-security Easy-In/Easy-Out door latch designed for simplicity and safety. The outer door latch closes smoothly with a single-hand action over a cam action bearing. The outer door can be secured with an independent padlock provided by customer.

1 2

11

Inner Door Latches provide single-hand access.

6

5

4

Panasonic microprocessor-based controller includes comprehensive set-point, alarm, monitoring and diagnostic functions.

10 7

8

3

9

1.

The insulation used in Panasonic’s PRO Series

4.

ultra-low temperature freezers is high density rigid, foamed-in-place polyurethane. This

5.

design prevents the insulation layers from

2.

Ergonomic one handed Easy-In / Easy Out outer door latch will accept a padlock.

3.

28

Microprocessor-based controller.

8.

Insulated sealing inner doors help maintain

9.

“Eagle Beak” inner door latches.

maximum reliability.

10.

filter cleaning.

Multiple access ports permit independent probes, instrumentation or liquid CO2

Easy front access to washable, electrostatic condenser filter for routine condenser air

Panasonic designed compressors specifically designed for low temperature use offer

openings. Two inner doors are standard.

6.

7.

High impact recessed casters simplify installation.

interior temperature during routine

distortion and cracking that might occur due to temperature differences inside and out.

Remote alarm contacts can be connected to independent monitoring system.

back-up system injection.

11.

Vacuum release port.

Panasonic Healthcare Corporation of North America | Ultra-Low and Cryogenic Freezers

PRO Series Comparative Energy Performance Less Emission

Panasonic freezers provide reduced operational cost for highly efficient sample storage*.

Panasonic freezers emit less heat into the laboratory, minimizing air conditioning costs*.

Panasonic freezers help the environment by reducing carbon footprint.

Power Consumption By Capacity (KW/day/box capacity)

Total annual operating cost for operation and cooling by capacity

Annual CO2 Emissions

by Box Capacity

2.5

10

2

*Based on internal performance data. Tested in 25째C ambient environment.

Freezer cycling at -80째C. Cabinet volume, 25 cu. ft. Average cabinet temperature based on temperature mapping (15 thermocouples).

MODEL NUMBER

10.93

4

Dollars

6

11.11

2.21

0.5

2.25

1.0

1.73

Watts

1.5

8

10.27

2.0

1.0 0.9 0.8 0.7 0.6 0.5 0.4 0.3 0.2 0.1 0

0.82

12

Dollars / Cubic Foot

3.0

Panasonic

Brand A

MDF-U7486SC-PA

MDF-U5486SC-PA

0.88

Operating Cost

0.89

Power Consumption

Brand B

MDF-U7486SC-PA

REFRIGERATION SYSTEM, HFC REFRIGERANTS, COOL SAFE HIGH PERFORMANCE COMPRESSORS HIGH STAGE

1100 W

1100 W

LOW STAGE

1100 W

1100 W

Standard

Standard

Standard (< 51dB(A))

Standard (< 51dB(A))

VOLTAGE BOOSTER, BUILT-IN SOUND ABATEMENT CONSTRUCTION SHELF ACCESS PORT REFRIGERANTS ALARM REMOTE ALARM CONTACT

Stainless steel, adjustable 3 shelves .066" (17 mm) diameter, HFC refrigerants High/low temp, Power failure, Filter check, Battery check N.O. and N.C., allowable contact capacity: DC30V, 2A

29

Cryogenic Freezer Temperature Uniformity for Long-term Storage.

Models: MDF-C2156VANC-PA

SAVE

What keeps our Cryogenic freezer so stable?

Panasonic Cryogenic freezer maintains uniform temperature of -150°C for stable, long-term preservation of cells and tissue. Panasonic VIP® PLUS Cryogenic Series -150°C ultra-low temperature freezer achieves more storage capacity than a conventionally insulated freezer without increasing footprint.

Liquid Nitrogen freezer ( Vapor Phase )

Panasonic MDF-C215VANC-PA mechanically refrigerated cryogenic freezer

Uniform Cryogenic Temperatures ±5ºC uniformity* in a mechanically refrigerated design promotes better top-to-bottom uniformity than liquid nitrogen vapor-phase storage, without the concern of cross-contamination often associated with liquid nitrogen (liquid phase storage). *Based on internal validation data tested at -150°C setpoint, in an empty chamber with 23°C ambient temperature.

Comparison of temperature distribution in a liquid nitrogen freezer (vapor phase) and Panasonic’s MDF-C2156VANC-PA mechanically refrigerated cryogenic freezer. Graph shows temperatures at different locations within the chamber. This data demonstrates that 100% of the MDF-C2156VANC-PA storage space maintains uniform storage temperatures safely below -130ºC, while temperature in LN2 vapor system is dependent on storage location. * The data may vary depending on the use, circumstances and optional accessories.

Validation documents can be provided for each serial number with an additional fee.

30

Panasonic Healthcare Corporation of North America | Ultra-Low and Cryogenic Freezers

Product Features Warning indicator (Lit even during power outage)

Setting input

Graphic Display (LCD)

Warning information Status display

Buzzer silence: Hold for alarm test

Door display

Patented revolutionary vacuum insulation cabinet construction reduces wall thickness and achieves more storage capacity than a conventionally insulated freezer without increasing the footprint.

VIP® PLUS offers superior performance in insulating properties providing unsurpassed uniformity in the chamber- top to bottom, side to side, front to back.

The temperature inside the freezer can be set and monitored easily by means of precise microprocessor temperature control with an LCD graphic display. The controller utilizes a platinum RTD sensor which is extremely precise and durable.

The MDF-C2156VANC-PA is equipped with LN2 backup system as standard to prepare for any contingency. The built-in LN2 back-up system is self activated if a power outage occurs. This feature helps ensure that the contents will be protected in the event of any power failure.

Status Alert monitors ambient and system conditions continuously and notifies of any abnormalities before a problem can occur. In case of power failure or an irregular rise in temperature, a rechargeable, high capacity battery-operated indicator lamp and alarm will be activated.

Graphic LCD panel with pop-up menu function on control panel provides a precise visual display and allows intuitive operation.

MODEL NUMBER TEMPERATURE RANGE MAX COOLING PERFORMANCE UNIFORMITY CAPACITY

Achieves 50% higher energy conservation than conventionally insulated model.

The newly developed refrigeration system and the freezer structure offer a quiet environment.

MDF-C2156VANC-PA -125°C to -150°C (1°C increments) -150°C (ambient temp 30°C) ±7°C at -150°C (empty chamber, ambient temp 24°C) 8.2 cu.ft.

231 liters

EXTERIOR DIMENSIONS (W X F-B X H)

68.1” x 30.1” x 39.8” 1730 x 765 x 1010 mm

INTERIOR DIMENSIONS (W X F-B X H)

29.9” x 19.5” x 24.2” 760 x 495 x 615 mm

NET WEIGHT

Approx.715lbs (325kg)

ACCESS PORT

40mm diameter, 1 location

COMPRESSOR

Hermetic type, 1100W (high stage side) 1100W (low stage side)

REFRIGERANTS ALARM REMOTE ALARM CONTACT POWER REQUIREMENTS

CFC Free High/Low temperature, power failure, filter check, self diagnosis, lid check Allowable contact capacity DC 30V, 2A 208V-230V, 1 phase, 60Hz NEMA 6-15R (15 Amp) Receptacle

31

Chest Freezers Space-Saving stability.

Models: MDF-594C-PA, MDF-794C-PA

MDF-C8V1-PA

SAVE

What makes Chest freezers compact yet equally effective?

All ultra-low chest models use Panasonic-designed compressors for ultra-low temperature applications.

Manufactured with foamed-in-place insulation, they are ideally suited for use in hospitals and laboratories for long-term preservation and storage of specimens and components, as well as materials testing.

Microprocessor Controls Comprehensive set-point, alarm, monitoring, and diagnostic functions based on Panasonic-built microprocessor controller with digital display of all input/output functions.

Panasonic-Designed Refrigeration and Compressors Designed by Panasonic specifically for rugged ultra-low temperature applications in a laboratory environment.

CFC-free refrigerants only.

High-performance refrigeration system with foam-in-place cabinet insulation maximizes interior temperature uniformity and protects against fluctuating ambient temperatures.

High Density Blown-In Foam Insulation and Heated Gasket Seal In ultra-low temperature freezers, effective insulation is critical.

The insulation used in Panasonic ultra-low freezers is two layers of rigid, foamed-in-place polyurethane, placed together to form a double-insulation wall

32

This design prevents the insulation layers from distortion and cracking that might occur due to temperature differences inside and out.

Frost and icing on the top edges and gaskets are prevented by utilization of a heated mullion, which recycles heat from the refrigeration system without affecting chamber uniformity.

Built-In Temperature & Power Failure Alarms (Lamp/Buzzer) In case of power failure or an irregular rise in temperature, a high capacity, rechargeable battery-operated indicator lamp and alarm will be activated.

Optional CO2 and LN2 back-up systems are available and are self-activated when a power outage occurs. This equipment helps ensure that the contents will be protected in the event of any power failure or mechanical trouble.

Panasonic Healthcare Corporation of North America | Ultra-Low and Cryogenic Freezers

Optional Accessories MODEL NUMBER TEMPERATURE RANGE MAX COOLING PERFORMANCE EFFECTIVE CAPACITY

MDF-C8V1-PA -60°C to -80°C (-1°C increments) -80°C (Ambient Temp 30°C) 3.0 cu.ft. (85 liters)

EXTERIOR DIMENSIONS (W X F-B X H)

21.6” x 27.0” x 37.2” / 550 x 685 x 945 mm

INTERIOR DIMENSIONS (W X F-B X H)

15.9” x 19.3” x 16.9” / 405 x 490 x 425 mm

NET WEIGHT STORAGE CAPACITY OUTER DOOR / INNER DOOR INSULATION COOLING SYSTEM

Approx. 148lbs (67kg) 2" Box: 42 pcs. (SCR-072 x 6 racks) 3" Box: 30 pcs Outer Lid: 1 piece; Inner Lid: 1 piece VIP® PLUS rigid polyurethane foam (HC) 115V / 60Hz / 1 Phase NEMA 5-15P Plug

COMPRESSOR

Rotary Type

REFRIGERANT

HFC

EVAPORATOR ALARM SYSTEM

MODEL NUMBER

Tube on Sheet Type High / Low Temp. Alarm (±5°C to ±20°C); Power Failure Alarm; Remote Alarm Contact: DC30C, 2A (N.O./N.C.)

MDF-594C-PA

MDF-794C-PA

TEMPERATURE RANGE

-20°C to -86°C

CABINET INSULATION

Rigid polyurethane foamed-in place

EXTERIOR DIMENSIONS (W X F-B X H)

79.1” x 30.3” x 42.1” / 2010 x 770 x 1070 mm

101.2” x 30.3” x 42.1” / 2570 x 770 x 1070 mm

INTERIOR DIMENSIONS (W X F-B X H)

50.3” x 19.7” x 30” / 1280 x 500 x 762 mm

72.4” x 19.7” x 30” / 1840 x 500 x 762 mm

19.2 cu.ft. (487 Liters)

24.8 cu.ft. (701 Liters)

EFFECTIVE CAPACITY EXTERIOR CABINET

Painted Steel

INTERIOR CABINET

Stainless Steel

INNER SUB-LID NET WEIGHT (APPROX.)

3

4

672lbs (303kg)

827lbs (347kg)

COMPRESSOR (HIGH STAGE)

Hermetic type 750W

Hermetic type 1100W

COMPRESSOR (LOW STAGE)

Hermetic type 750W

Hermetic type 1100W

EVAPORATOR (HIGH STAGE)

Cascade condenser

EVAPORATOR (LOW STAGE)

Tube on sheet (shared with interior)

CONDENSER (HIGH STAGE)

Fine and tube type

CONDENSER (LOW STAGE)

Shell and tube type

TEMPERATURE CONTROL

Microprocessor: Keypad input; Temp. input range: -20°C to -86°C (1C increment); Set value memory: nonvolatile memory

TEMPERATURE DISPLAY

Digital Display

SENSOR ALARM SYSTEM POWER REQUIREMENT

Platinum Resistance (Pt. 100) Selectable high temp. alarm (+10°C & +15°C from set point), Power Failure alarm, Filter check lamp, Remote alarm contact 208 / 220V / 60hz built-in voltage booster

33

Precise Uniformity Temperature Stability Micro-processor based controller

LED Display

Quiet, Reliable Compressors Cycle Defrost

SAVE

Energy Savings Alarms & Monitoring

CFC-Free

Service

Ergonomic Design

Stable 5ยบC

The Industryâ&#x20AC;&#x2122;s Most Complete Refrigeration Solutions Table of Contents Ideal equipment for your refrigeration needs.

Feature Matrix

36

38

Panasonic Refrigerators & Freezers Ideal equipment for your refrigeration needs

36

Feature Overview

40

Biomedical Freezers

42

Biomedical Refrigerators with Freezers

44

Laboratory Refrigerators

48

Pharmaceutical Refrigerators

49

Blood Bank Refrigerators

52

Undercounter Refrigerators and Freezers

54

Ideal equipment for your refrigeration needs.

Biomedical Freezers

Refrigerators & Freezer Combo

Laboratory Refrigerators

-20°C to -30°C

2°C to 23°C

MDF-U731-PA, MDF-U731M-PA,

-20°C to -30°C (Freezer) 2°C to 14°C (Refrigerator)

MDF-U5312-PA, MDF-U334-PA

MDF-215F-PA, MDF-414F-PA,

MPR-721-PA, MPR-721R-PA MPR-1411-PA, MPR-1411R-PA

MPR-715F-PA

SAVE

SAVE

SAVE

Ideal for long or intermediate-term storage and constructed with high-performance laboratory and clinical-grade refrigeration systems. These freezers are used in medical, biotechnology and industrial labs for storage of blood components, enzymes, culture media, reagents, specimens and vaccines.

The biomedical refrigerators with freezer combine high performance refrigeration, control and alarm/monitoring systems with energy efficient, cost-effective cabinet design. One unit with dual temperature zone needs only minimal space.

Ideal temperature environment for clinical research, pharmaceutical and industrial use. Adjustable shelves and wide range setpoint for varying laboratory applications including chromatography and pharmaceutical storage.

36

Panasonic Healthcare Corporation of North America | Refrigerators and Freezers

Blood Bank Refrigerators

Undercounter Refrigerators & Freezers

Pharmaceutical Refrigerators

4°C

10°C to -20°C

2°C to 14°C

MBR-107D(H)-PA, MBR-304GR-PA,

SR-L6111W-PA, SR-L4110W-PA,

MPR-514-PA, MPR-514R-PA,

MBR-704GR-PA, MBR-1405GR-PA

SR-L4110WSEC-PA , SF-L6111W-PA,

MPR-1014-PA, MPR-1014R-PA,

HF-5017W-PA, HF-5017WSEC-PA

MPR-S313-PA

SAVE

SAVE

SAVE

Panasonic blood bank refrigerators are designed to create stable, reliable temperature control pre-set to 4°C with precise top-to-bottom temperature uniformity making them ideal for the storage of whole blood.

Panasonic undercounters represent stringent quality control processes making them the highest quality laboratory appliance available for demanding standards of clinical, life science, pharmaceutical, biotechnology, and industrial laboratories.

The slim design and optional sliding shelves give Pharmaceutical refrigerators an ergonomic advantage - these refrigerators offer a complete, integrated solution for the growing requirements of strict and exact storage temperatures to store pharmaceuticals, medicines and temperature-sensitive biologicals.

37

Feature Matrix BIOMEDICAL FREEZERS

BIOMEDICAL REFRIGERATORS WITH FREEZERS

LABORATORY REFRIGERATORS

PHARMACEUTICAL REFRIGERATORS

BLOOD BANK REFRIGERATORS

UNDERCOUNTER REFRIGERATORS AND FREEZERS

-30°C to -20°C

-30°C to 20°C

2°C to 23°C

2°C to 14°C

2°C to 14°C

-20°C to 10°C

9.7 Cu.Ft

6.2 Cu.Ft

24 Cu.Ft

12 Cu.Ft

2.8 Cu.Ft / 10.6 Cu.Ft

6 Cu.Ft

17 Cu.Ft.

12 Cu.Ft.

48 Cu.Ft.

17 Cu.Ft.

21.8 Cu.Ft.

4.9 Cu.Ft.

23 Cu. Ft.

14.7 Cu. Ft.

36 Cu. Ft.

45.9 Cu. Ft.

5.4 Cu. Ft.

OPERATING MODE (AUTOMATIC)













OPERATING MODE (MANUAL)





GENERAL STORAGE









REAGENTS AND KITS









CULTURE MEDIA

























OPERATING RANGE

SIZE RANGE

MAJOR APPLICATIONS

BIOLOGICALS ENZYMES





VACCINES



 

PATIENT MEDICATION



WHOLE BLOOD PLASMA





SHELF LIFE TESTING



















CHROMATOGRAPH APPARATUS TEST SAMPLES

38







Panasonic Healthcare Corporation of North America | Refrigerators and Freezers

Vaccine Specific Preservation Panasonic offers a selection of Biomedical Refrigerators and Freezers that include significant design and performance properties, which differentiate them from conventional household refrigerators. These are designed for specific vaccine storage applications, making them ideally suited for use in clinics, hospitals, retail pharmacies, and laboratories to store vaccines.

Comparison with Domestic Refrigerators MPR SERIES

DOMESTIC REFRIGERATOR

CFC-FREE, RELIABLE TEMPERATURE CONTROL NOT AFFECTED

BY AMBIENT TEMPERATURE



X

DIGITAL DISPLAY OF CHAMBER TEMPERATURE



X

PRECISE TEMPERATURE SETTING OF CHAMBER WITH MICROPROCESSOR CONTROL



X

DIGITAL VARIABLE TEMPERATURE CONTROL OF REFRIGERATOR (2°C TO 14°C)



X

VARIABLE TEMPERATURE CONTROL OF FREEZER (-20°C TO -30°C)



Max/Mid/Min

UNIFORM TEMPERATURE AT ALL SHELF LEVELS



X

SEPARATE OPERATION OF REFRIGERATOR AND FREEZER



X

WINDOW FOR VIEWING



X

OPTIMIZED SPACE DEDICATED TO STORAGE



X

ACCESS PORT



Some Models Yes

TEMPERATURE RECORDER (OPTIONAL)



X

DOOR AJAR TRIGGERS INDICATOR LIGHT AND AUDIBLE ALARM (OPTIONAL)



Some Models Yes

IRREGULAR TEMPERATURE TRIGGERS ALARM (OPTIONAL)

     

X X X X X 

PRODUCT CHARACTERISTICS

REMOTE ALARM TERMINAL SET TEMPERATURE DEVIATION SELF DIAGNOSTIC FUNCTION UNIQUE CYCLE DEFROST / AUTOMATIC DEFROST SYSTEM CONDENSATE EVAPORATOR

39

Features - Overview Panasonic offers a selection of Refrigerators and Freezers that include significant design and performance properties. These units are more suitable for pharmacy and biomedical use than conventional household refrigerators & freezers.

Precise Uniformity with Panasonic Design

Alarms & Monitoring

Compressors are specifically designed for demanding scientific and laboratory storage, offering precise uniformity throughout the chamber.

Comprehensive setpoint, alarm, monitoring and diagnostic functions supervised by Panasonic-built microprocessor controller with digital display of all input/output function.

Temperature Stability

Energy Savings

Forced Air Circulation technology quickly restores temperature uniformity following routine door openings. In addition, Panasonic cycle defrost (in most units) initiates only as required, maintaining internal temperature uniformity during the process.

SAVE

Always a leader in environmentally friendly technology, Panasonic refrigerators use commercially available HFC refrigerants and CFC-free insulation.

Panasonic is committed to developing green technologies that provide energy efficiency, resulting in lower operational costs with less impact on the environment.

Panasonic Cycle Defrost

Cycle Defrost Function for Auto Defrost Units

40 35 30

Ambient Temp.

20 10 5

Temp (0C)

Panasonicâ&#x20AC;&#x2122;s Cycle Defrost system design ensures that defrost occurs only when necessary and not based on time, like other competitive units. This system runs automatically so there is no need to turn off power for defrosting. Temperature increase during defrost is minimal with no temperature spikes. The evaporation heater also adds additional protection against decrease in cabinet temperature, which can be caused by low ambient temperature.

0

Inside Temp.

8

Cycle Defrost Function Data 40 35 30

4°C 0°C surface of evaporator Compressor-ON (Time)

Heater-ON

Compressor-ON

Temp (0C)

20

Heater-ON

Ambient Temp.

Temp. Rise During Defrost Cycle

10 5 0

8

16 (Time)

40

24

Others Auto Defrost Refrigerator

chamber air

Compressor-ON

16 (Time)

24

Panasonic Healthcare Corporation of North America | Refrigerators and Freezers

Micro-processor based controller Panasonic Micro-processor based controller manages set-points and actual conditions to provide the highest level of security for the stored products.

Door check indicator: The red LED lamp is lit when the outer door is opened.

Interior Light Switch Alarm lamp: This lamp is flashed when the audible alarm is activated

Enables interior lightening system (on applicable models).

Buzzer stop key: To silence the audible alarm, press this key.

The remote alarm is also silenced by pressing this key.

Digital temperature indicator: This indicator shows the present chamber temperature or set.

Set key: Defaults to previously set temperature when required.

41

Biomedical Freezers Panasonic MDF series biomedical freezers are designed for long or intermediate-term storage at temperatures as low as -30°C. Constructed with high-performance laboratory and clinical-grade refrigeration systems, these freezers are used in medical, biotechnology, and industrial labs for storage of blood components, enzymes, culture media, specimens, vaccines etc.

40

Temperature (˚C)

Models: MDF-U334-PA, MDF-U5312-PA, MDF-U731/731M-PA SAVE

20 0 –20 –40

Performance Data -MDF-U731-PA 40 20 0 –20 –40

1

0

2

3

4

1

0

2

3

4

5

Time (hr.)

Pull-up characteristics during power failure Pull-up characteristics

under no-load condition

Temperature (˚C)

Temperature (˚C)

Pull-down characteristics under no-load condition Pull-down characteristics

Pull-down characteristics under no-load condition

20 0 –20

40–40

5

30 Temperature (°C)

Time (hr.)

during power failure

40

1

0

2

3

4

5

Time (hr.)

20

Pull-up characteristics General Purpose Storage, Maintenance-Free (Auto-Defrost Models) 10 during power failure Temperature (˚C)

0 40 at -30°C with auto-defrost and consistent temperature Storage control below -20°C during -10 defrost cycle. Maintenance-free storage with no end user intervention to defrost unit and 20 -20 clean up condensate. Precision temperature uniformity throughout chamber due to forced air 0

-30

–20

-40

circulation with dual fans.

Performance Data -MDF-U334-PA &1 MDF-5312-PA 2 3 4 5 6 –40

1 0 characteristics 2 under no-load 3 4 5 Pull-down condition

Pull-down characteristics during power failure

Time (hr.)

40

40

30

30

MDF-U334-PA

20

Temperature (°C)

Temperature (°C)

7

Time (Hr)

10 0 -10 -20 -30

MDF-U5312-PA

20 10 0 -10 -20 -30

-40

-40

1

2

3

4

5

6

7

1

Time (Hr)

2

3

4

5

6

7

Time (Hr)

Enzyme and Biologics Preservation (Manual Defrost Models) 40

Temperature (°C)

30 Uniform temperatures are maintained throughout the chamber using shelf freezing construction.

Since there is no defrost cycle, the inner chamber temperature offers outstanding 20 uniformity and stability without temperature spikes. Standard door lock for an independent 10

padlock ensure extra safety.

0

42

-10 -20

Panasonic Healthcare Corporation of North America | Refrigerators and Freezers

Microprocessor Controls: Comprehensive setpoint, alarm, monitoring, and diagnostic functions supervised by the MDF Series microprocessor controller with digital display of all input / output function.

Enzyme Storage Freezer Bins (MDF-U731M-PA Only):

Temperature °C

The optional full storage system, Model #: 730MFB creates a flexible and convenient inventory system for enzymes and many other types of samples. The total system includes 14 storage bins and additional wire shelving.

Freezer Temp: Bins vs. No Bins

Without Bins With Bins

Time Since Opening Door (min)

Door open to 90° angle for 30 seconds

Sample Storage Security: Keyed door lock and integrated padlock hasp are standard features.

Quiet Operation: The MDF Series’ energy-efficient refrigeration design requires no noisy condenser fan. In combination with low dB level compressor, this unit is uniquely quiet and perfect for in-lab installations.

Adjustable Shelving System: Four adjustable wire shelves with over 100 pound capacity each allows for flexible material storage configurations.

Specifications MDF-U5312-PA

MDF-U334-PA

MDF-U731-PA

MDF-U731M-PA

EXTERIOR DIMENSIONS (W X F-B X H)

MODEL NUMBER

31.5” x 30.4” x 70.9” 804 x 772 x 1802 mm

24.2” x 27.9” x 63.8” 614 x 709 x 1620 mm

30.3” x 32.7” x 77.0” 770 x 830 x 1955 mm

30.3” x 32.7” x 77.0” 770 x 830 x 1955 mm

INTERIOR DIMENSIONS (W X F-B X H)

25.9” x 23.9” x 50.1” 658 x 607 x 1272 mm

19.3” x 19.1” x 50.8” 490 x 485 x 1290 mm

25.6” x 28.0” x 53.9” 650 x 700 x 1370 mm

25.6” x 27.5” x 59.8” 650 x 700 x 1520 mm

17.0 cu.ft.

482 L

9.7 cu.ft.

274 L

22.0 cu.ft.

623 L

24.4 cu.ft 690 L

CAPACITY CONTROL RANGE

-20ºC to -30ºC, with memory backup

DEFROST SYSTEM

Manual, defrost button on display

STORAGE

ACCESS PORT COOLING SYSTEM REFRIGERANT VISUAL AND AUDIBLE ALARM SYSTEM CALIBRATION ELECTRICAL REQUIREMENTS WEIGHT

SECURITY

-20°C to -35°C Automatic Defrost

-18°C to -30°C Manual Defrost

Top: 6 small baskets (3 fixed evaporator shelves)

Top: 4 large baskets (446 x 369 x 220 mm)

Bottom: 4 large baskets (1 evaporator shelf and bottom)

Bottom: 1 small basket (487 x 221 x 155 mm)

30 mm diameter, rear

30 mm mid left wall

Diameter 30 mm (left) / Diameter 20 mm (top)

Hermetic rotary compressor, ½ HP

Hermetic rotary compressor 1/4 HP

½ HP (400W), Hermetic Rotary Type

R-404A (HFC)

R-134a (HFC)

Environmentally friendly, HFC refrigerant (R-404A)

High/low temperature alarm (SV ±5ºC to ±15ºC adjustable with ring-back function); Power Failure; Remote alarm contacts (N.O./N.C.)

High/Low temperature alarm, door ajar alarm, power failure, remote alarm contacts, memory backup

Zero adjustment via control panel 115V, 60 Hz, 1 phase, 2.1 amps running, NEMA 5-15P plug

115V, 60 Hz, 15 Amp breaker, NEMA 5-15P Plug

Net Unit Weight: 295 lbs / 134 kg

Net Unit Weight: 178 lbs / 81 kg

Net Unit Weight: 335 lbs / 152 kg

Display Keylock, Keyed outer doors, Standard paddlock hasp per door

Display Keylock, Keyed outer doors, Standard paddlock hasp

Display Keylock, Keyed outer doors, Standard paddlock hasp

43

Refrigerator & Freezers Combo The MPR Series biomedical refrigerators with freezer combine high performance refrigeration, alarm monitoring systems with energy efficient cabinet design. One unit with dual temperature zone needs only minimal space. The two door design reduces air loss during door openings.

Models: MPR-215F-PA, MPR-414F-PA, MPR-715F-PA SAVE

Energy Savings

Temperature Uniformity

Energy-saving storage solutions for uniformity and reliability with dual temperature zones.

Refrigeration systems designed for precise and stable vaccine and biological storage.

MPR-215F-PA MODEL EFFECTIVE CAPACITY

MPR-414F-PA

Refrigerator

Freezer

Refrigerator

Freezer

Refrigerator

Freezer

6.2 cu. ft.

176 L

1.4 cu. ft.

39 L

12.0 cu. ft.

340 L

2.9 cu. ft.

82 L

14.7 415 L

6.2 176 L

EXTERNAL DIMENSIONS (W X F-B X H)

21.3” x 21.9” x 70.6” 540 x 557 x 1794 mm

WEIGHT

Styrene resin

Colored aluminum plate

2oC to 14oC Ambient temperature: (-5oC to 30oC, no load)

-20oC to -30oC Ambient temperature: (-5oC to 30oC, no load)

COMPRESSOR

ACCESS PORT

44

Colored aluminum plate

PCM Painted Steel

2oC to 14oC Ambient temperature: (-5oC to 35oC, no load)

-20oC to -30oC Ambient temperature: (-5oC to 35oC, no load)

2°C to 14°C Ambient temperature: (-5oC to 30oC, no load)

-20°C to -30°C Ambient temperature: (-5oC to 30oC, no load)

Direct Cooling (manual defrost)

Fan-Forced air circulation

Direct Cooling (manual defrost)

Fan-Forced air circulation

Direct Cooling (manual defrost)

55W

55W

160W

160W

150W

200W

Large: 2 (55 lbs / shelf) Small: 3 (33 lbs / shelf)

1 (22 lbs / shelf)

3 (55 lbs / shelf)

2 (33 lbs / shelf)

30 mm (rear)

30 mm (rear)

30 mm (rear)

30 mm (rear)

R-134A (HFC) 5 (44 lbs / shelf)

1 (22 lbs / shelf)

30 mm (left)

30 mm (left)

4 casters with 2 adjustable leveling feet High/low temperature alarm, Door ajar alarm, Memory back up during power failure Self-diagnostics, remote alarm contacts (N.O./N.C., DC30V, 2A). Door key lock. Critical component lifespan alarm)

VOLTAGE

OPTIONS

Stainless steel

Fan-Forced air circulation

CASTERS ALARM AND SAFETY

371 lbs 168 kg

Microprocessor LED Display

REFRIGERANT SHELVES

277 lbs. 126 kg

CFC-Free rigid polyurethane foamed in place

TEMPERATURE CONTROL COOLING METHOD

35.4” x 28.1” x 75.2” 900 x 715 x 1910 mm

Polyester resin finish baked on zinc galvanized steel

INSULATION TEMPERATURE RANGE

31.5” x 23.6” x 71.0” 800 x 600 x 1805 mm

189 lbs. 86 kg

EXTERIOR INTERIOR

MPR-715F-PA

115V / NEMA 5-15 • 2-pen type circular temperature recorder (MTR-C955) • LabAlert Wireless Monitoring

•2 -pen type circular temperature recorder (MTR-C955) •D rawers for the bottom left compartment (MPR-41R) • LabAlertTM Wireless Monitoring

•2 -pen type circular temperature recorder (MTR-C955) •P ower failure alarm (MPR-48B) • LabAlert Wireless Monitoring

Panasonic Healthcare Corporation of North America | Refrigerators and Freezers

Microprocessor Controls: • NEW energy saving LED lighting.

MPR-715-PA

• Microprocessor controller and interior forced air circulation

• Integrated alarm functions

Cycle Defrost: Unique cycle defrost (refrigerator only) initiates only as required and maintains internal temperature uniformity, without fluctuation due to a defrost cycle.

Refrigeration Systems Separate refrigeration systems and compressors allow differential control of individual refrigerator and freezer compartments, allowing freezer section to maintain temperatures as low as -30°C.

The MPR series combo units have two separate specially designed compressors and offers quiet operation.

Cabinet Construction: • Double-pane windows with heat reflection film reduces the condensation

• Calibration adjustment through the control panel is available.

45

Laboratory Refrigerators Panasonic Laboratory refrigerators provide stable and reliable refrigerated environment for carrying laboratory requirements, making them ideal for clinical research, pharmaceutical, and industrial use.

Adjustable shelves and wide range setpoint for varying laboratory applications, including chromatography and pharmaceutical storage.

Chamber temperature (°C)

Models: MPR-721-PA, MPR-721R-PA, MPR-1411-PA, MPR-1411R-PA MPR-1411-PA: Set at 5°C 100mm (3.9 inches) inside of shelves MPR-1411R-PA: Set at 5°C 100mm (3.9 inches) inside of drawers Standard domestic refrigerator

Relationship between chamber temperature 2 Domestic and ambient temperature Lowest

Easy-to-Manage Layout with Large Capacity

(Comparison with 0standard domestic 5 10 15 refrigerators) 20 25 30

The interior layout flexibility of the MPR series refrigerators due to adjustable shelves makeDomestic them ideal Highest 8 for runningHighest experiments that require 6changeable shelf configurations.

The spacious interiors with multiple 4capacity refrigerators allow Lowest for accommodation of column 2 Domestic chromatography apparatus or large Lowest volumes of reagents, test samples, 0 5 10 15 20 25 30 35 and biologicals.

Ambient temperature (°C)

35

Highest 6 4 Lowest 2

0

35

Domestic Lowest 5

10

15

20

25

30

35

Domestic Highest

8

Chamber temperature (°C)

stic t

Domestic Highest

8

Chamber temperature (°C)

Chamber temperature (°C)

Ambient temperature (°C)

west

0

Domestic Highest 8 MPR-1411-PA: Set at 5°C SAVE 100mm (3.9 inches) inside of shelves 6 MPR-1411R-PA: Set at 5°C 100mm (3.9 inches) inside of drawers Standard domestic refrigerator 4

Highest 6

Lowest

4 2

Domestic Lowest

0

5

Ambient temperature (°C)

10

15

20

25

30

Ambient temperature (°C)

MPR-1411R-PA: Set at 5°C 100mm (3.9 inches) inside of drawers

MPR-1411-PA: Set at 5°C 100mm (3.9 inches) inside of shelves

Standard domestic refrigerator

Standard domestic refrigerator

35

Alarms & Safety Features FEATURE

TRIGGER

TYPE OF ALARM/RESPONSE

HIGH TEMPERATURE ALARM

2°C to 14°C (selectable) above setpoint

Flashing LED & audible alarm after 15 minutes

LOW TEMPERATURE ALARM

2°C to 14°C (selectable) below setpoint & 0°C or lower

Flashing LED & audible alarm

Lock ON

Set temperature and alarm points cannot be altered

Power failure

Memory of settings

Door not closed

Door ajar lamp ON, adjustable audible alarm from 1 to 15 minutes

Sensor failure and fan or compressor abnormality

Error code shown

REMOTE ALARM CONTACTS

N.O. and N.C. contact available for hook up to an auxiliary alarm system

—

TEMPERATURE RECORDER

Optional, Model #MTR-C954, 7-day 6” circular chart or touch panel digital temperature recorder

—

TEMPERATURE LOCK MEMORY BACKUP DOOR AJAR SELF DIAGNOSTICS

46

Panasonic Healthcare Corporation of North America | Refrigerators and Freezers

Performance Data

Performance Performance datadata (Reference (Reference Data) Data)

20

20

10 0 –10

10 0

–10 0 0

60

60 120 120 180 Time (min.)

Time (min.)

180 240

240

35

35

30

30

25

25

20

20

15

15

10

10

5

5

0

0

500 500 With a temperature range of 2°C to 23°C, 450 450 400 MPR 400 Series refrigerators are Panasonic’s 350 350 ideally suited for tests that require a stable, 300 300 250 250 or general cold storage.

Air temp.

Airattemp. center atof center chamber of chamber cool temperature (Ambient (Ambient temp. 35°C) temp. 35°C)

Initial conditions: Initial conditions: chamber chamber stable atstable 2°C at 2°C

50

50 100 100 150 150 200 200 250 Time (min.)

Time (min.)

250 300

300

Inside thermal load (W)

30

Temp.(°C)

30

Air temp.

Airattemp. center atof center chamber of chamber (Ambient (Ambient temp. 35°C) temp. 35°C)

Wide Settable MPR-1411-PA MPR-1411-PA Test of Test permissible of permissible Temperature Range insideinside thermal thermal load load Inside thermal load (W)

40

Temp. in chamber (°C)

Temp. in chamber (°C)

40

MPR-1411-PA MPR-1411-PA Power-off, Power-off, Warm-up Warm-up characteristics characteristics (no-load) (no-load)

Temp.(°C)

MPR-1411-PA MPR-1411-PA Pull-down Pull-down characteristics (no-load) characteristics (no-load)

200 150 100 50 0

0

200 150 100 50 0

05

10 5 10 15 15 20 20 25 25 30 Ambient Ambient temp. temp.

(C) (C) 23C 10C 5C 2C

Large Fans:

35 30

35

23C 10C 5C 2C

The quiet 4.7”-diameter fan ensures an even temperature throughout the cabinet (MPR-1411R-PA models have a double flow system with two fans). Because of this heat spots from powered test apparatus are minimized and recovery characteristics after door openings are outstanding.

Easy Access Front Control Panel: Large LED display of actual temperature with intuitive touch pad setting makes operation simple.

MPR-721-PA MPR-1411-PA

Drawer Type Shelves: The “R” models are fitted with steel pull-out drawers. With a profile of 3.9 inches (100mm) and 20.8 inches (530mm). Front-to-back, these drawers are deep enough to hold large bottles or reagent kits.

They also allow convenient, spaceefficient storage and management of patient medications.

User Friendly Design & Double Door/Single Door Function: The broad, solid frames with effective gaskets ensure excellent temperature stability, while double-pane glass windows offer an excellent view of the interior. Optional panels are available to block out light.

Adjustable shelves: The shelves can be arranged to accommodate a tall apparatus, such as fraction collectors.

These shelves are deep by 24.4 inches (620mm) front-to-back.and strong enough to withstand a load of 110lbs.

47

EXTERIOR DIMENSIONS (W X F-B X H) VOLUME (CU.FT.)

MPR-1411-PA

MPR-1411R-PA

MPR-721-PA

MPR-721R-PA

56.7” x 32.67” x 76.8”

56.7” x 32.67” x 76.8”

30.3” x 32.67” x 77.0”

30.3” x 32.67” x 77.0”

48.2

48.0

24.2

23.7

EXTERIOR FINISH

Acrylic finish baked on zinc galvanized steel

INTERIOR FINISH DOORS

Acrylic finish baked on zinc galvanized steel 2x double pane glass doors, self closing

INSULATION

CFC-free rigid foamed-in-place polyurethane

ACCESS PORT LOCKS

1x double pane glass doors, self closing

3 x 30 mm (2 in sides, 1 in cabinet top) 2x cylinder type (each door)

1x cylinder type

SHELVES

8 (565w x 604d mm)

—

4 (565w x 604d mm)

—

DRAWERS

—

10 (550w x 530d mm)

—

5 (550w x 530dmm)

COOLING METHOD COMPRESSOR

Forced air circulation with double fan

Forced air circulation with single fan

250W hermetic rotary

200W hermetic rotary

EVAPORATOR

Forced air

CONDENSER

Fin tube type

Wire tube type, Filter-less design

REFRIGERANT

R-404a(HFC)

R-134a(HFC)

DEFROST METHOD TEMPERATURE CONTROL

Intelligent forced type (cycle defrost system), full automatic hot pipe for automatic condensate evaporation for condensate water Microprocessor controlled. 2°C to 23°C temperature range can be configured to 1°C increments

TEMPERATURE DISPLAY SAFETY FEATURES HIGH TEMPERATURE ALARM LOW TEMPERATURE ALARM

Digital type (1°C resolution) High temperature protection circuit, low temperature protection circuit, temperature lock, self diagnostics, memory backup (nonvolatile memory) When temperature 5°C or more above set level, flashing LED & buzzer after adjustable delay

When interior temperature drops to 0°C or lower, flashing LED & buzzer

DOOR AJAR ALARM INTERIOR LAMP

Flashing lamp when temperature 5°C or more above set point, buzzer after adjustable delay

Flashing lamp, adjustable delay (1-15min) 40W x 1, fluorescent lamp

20W x 1, fluorescent lamp

POWER SOURCE VOLTAGE NOMINAL BTU OUTPUT

115v 60Hz NEMA 5-15P (15 A) 1298btu

1159btu

Circular Chart Temperature Recorder, 7 Days

MTRC954

OPTIONAL ACCESSORIES CHART RECORDER WIRELESS MONITORING TOUCH-SCREEN TEMPERATURE 4-20MA OUTPUT RS-485 OUTPUT BATTERY KIT

48

LabAlert Cloud / App-based monitoring system Full Color Touch-Screen Digital Display

FT-560SN

Independent Analogue Output

MTR-420MAC

Independent Digital Output

MTR-480-PW

Batter Kit for power failure audible alarm

MPR-48B-PW

Panasonic Healthcare Corporation of North America | Refrigerators and Freezers

Pharmaceutical Refrigerators Panasonic Pharmaceutical Refrigerators offer a complete and integrated solution for the increased requirements of strict and exact storage temperatures for pharmaceuticals, medicines, vaccines, and other temperature sensitive biologicals. The slim front-to-back design and optional sliding shelve allows for an easy retrieval of your product.

Models: MPR-514-PA, MPR-514R-PA, MPR-1014-PA, MPR-1014R-PA, MPR-S313-PA SAVE

Uniform Storage Temperature − Ambient Temperature 10

Inside Temperature (˚C)

Inside Temperature (˚C)

SANYO MPR Effective 10 Temperature Control

A thermistor sensor monitors temperature inside the chamber.

Microprocessor and electronic temperature controls ensure 5 5 that the set temperature is maintained. Even with frequent door openings, the circulation fan provides rapid temperature adjustment0 for a highly reliable, stable preservation environment0 that is unaffected by ambient temperature.

Upper Limit of Cycle

-5

Center of Cabinet Lower Limit of Cycle

Ergonomic Design

Conventional RegulatoryRefrigerator Guidelines Panasonic MPR refrigerators are designed with regulatory compliance in mind. Exceptional uniformity is paired with easy calibration access to meet critical validated storage regulations.

Upper Limit of Cycle Center of Cabinet Lower Limit of Cycle

-5

The ergonomic a clear view of stored items through the large -10 design of the MPR series refrigerators provides-10 -5 0 10 20 30 -10 0 10 20 30 framed windows. The slim profile allows for easy retrieval of your products, without the concern for swinging Ambient Temperature (˚C) Ambient Temperature (˚C) door clearances. Users can choose from two types of interior shelving to suit their needs.

Uniform Storage Temperature − Cycle Defrost Defrosting is performed automatically during compressor “off” cycles by sensing frost levels. This way defrosting is performed only when required, further protecting the contents against unnecessary temperature rise.

Uniform Storage Temperature − Cycle Defrost

Panasonic

Conventional Refrigerator 40

35

Temperature (˚C)

Temperature (˚C)

40 Ambient Temp

30 20 10

Inside Temp

5 0

35 30

Ambient Temp

20

Temp. Rise During Defrost Cycle

10 5

8

16

24(hr)

0

8

16

24(hr)

49

Visual LED Alarm Alerts

Easy to read digital display

Audible and flashing LED visual alarms alert you to the unlikely event of either a high or low temperature condition. An overshooting prevention circuit automatically switches off the fan motor or heater, if the inside temperature rises abnormally..

Temperature readings are displayed in gradients of 1°C for configurable temperatures ranging from 2° to 14°C..

2ϒC to14ϒC (

Uniform Storage Temperature –Ambient Temperature (17.2 cu.

10 ft.)

ambient temp.

–5ϒC to35 ϒC

nt to assure the samples and temperature, traviolet light and important is temperature is occur which als. If the re is a risk of about by freezing. ure control onditions is very ur results!

10

Conventional Refrigerator

5 0

Upper Limit of Cycle Center of Cabinet -5 Lower Limit of Cycle

-5 10

0

Ambient Temperature( ϒC)

Upper Limit of Cycle Center of Cabinet Lower Limit of Cycle

-10 20 -10

1030 0

Ambient Temperature( ϒC)

20

Uniform Storage Temperature –Cycle Defrost

Temperature( ϒC)

35

Ambient Temp.

30 20 10

Inside Temp.

5 0

)

40 35

Temperature( ϒC)

SANYO MPR

40

th sliding racks. apacity: 1,034 (36.5 cu. ft.) ambient temp.

–5ϒC to35 ϒC

SANYO MPR

0

-10 -5

1013R

4ϒC (

5

)

Inside Temperature( ϒC)

Effective capacity: 489

Inside Temperature( ϒC)

d reliable environment — control o high-precision performanceMPR-513 for storage or research requirements

Conventional Refrigerator

30

Ambient Temp.

20

Temp. Rise During Defrost Cycle

10 5

8

16

0 24(hr)

8

16

24(hr)

and MPR-1013(R) User-friendly design: easy-viewing, easy-opening, and energy-saving

ted Plenums by

Sanyo’s plenum design features uniform cold air flow distribution throughout the chamber to ensure temperature monitors uniformity — essential for validated he storage requirements. or for rature. ion to emperar openings. ble and easier.

ciency

pressor, d by owerful and r

50

Ergonomic design

Safety is a Sanyo standard Worry free cycle defrosting system

The ergonomic design of the MPR series Even the best designed refrigerator With must Sanyo ’s cycle defrost system, refrigerators provides a clear view be of prepared for the unexpected. defrosting is performed automatically stored items through the large framed Cabinet construction during compressor “off ” cycles, and by windows.The slim profile allows for View easy-Window Design with protective film sensing frost levels. This way defrosting is reach retrieval of your products. Users can performed only when required, further to prevent shattered glass from scattering choose from two types to suit their needs; protecting the contents against unnecesonto the floor. Key Locked Doors one with all shelves wire or one with sary temperature rise. The defrosting Control safety devices sliding racks on one side. heater also acts as an emergency heat Audible and Flashing LED Visual alarms source to prevent samples from freezing. alert you to the unlikely event of either a High or Low Temperature condition. An HFC refrigerants & CFC-free over-shooting prevention circuit automatically switches off the fan motor insulation or heater, if the inside temperatureAlways rises a leader in environmentally friendly abnormally. technology, Sanyo refrigerators feature

•

Plenums Direct Airflow:

Panasonic’s plenum design features uniform cold air flow distribution throughout the chamber to ensure temperature uniformity – essential for validated storage requirements.

•

Cabinet Construction:

View window door design with protective film for safety. Key locked doors.

Black out glass design is optional..

•Remote alarm contacts

commonly available HFC refrigerants and CFC-free insulation.

Low/high temperature audible and visual alarms and remote alarm.

Control Panel

Panasonic Healthcare Corporation of North America | Refrigerators and Freezers

Specifications MODEL NUMBER

MPR-S313-PA

MPR-514-PA

MPR-514R-PA

MPR-1014-PA

MPR-1014R-PA

31.5” x 17.7 x 70.9” 800 x 450 x 1800 mm

35.4” x 23.6” x 70.5” 900 x 600 x 1790 mm

35.4” x 23.6” x 70.5” 900 x 600 x 1790 mm

70.9” x 23.9” x 70.5” 1800 x 600 x 1790 mm

70.9” x 23.9” x 70.5” 1800 x 600 x 1790 mm

12.0 cu.ft. / 340 L

17.2 cu.ft. / 489 L

17.2 cu.ft. / 486 L

36.5 cu.ft. / 1037 L

36.5 cu.ft. / 1037 L

adjustable

adjustable

½ adjustable, ½ roll-out

adjustable

½ adjustable, ½ roll-out

EXTERIOR

Baked on acrylic finish galvanized steel

Baked on acrylic finish galvanized steel

Baked on acrylic finish galvanized steel

Baked on acrylic finish galvanized steel

Baked on acrylic finish galvanized steel

INTERIOR

Stainless steel

Stainless steel

Stainless steel

Stainless steel

Stainless steel

4 sliding doors. Double paned glass window

2 sliding doors. Double paned glass window

2 sliding doors. Double paned glass window

2 sliding doors. Double paned glass window

4 sliding doors. Double paned glass window

2 lock, 2 keys

1 lock, 2 keys

1 lock, 2 keys

1 lock, 2 keys

1 lock, 2 keys

Rigid wire with clear coat finish

5 polyester coated wire shelves Load: 110 lbs per shelf

5 polyester shelves + 5 polyester coated sliding shelves Load: 44 lb per shelf

5 polyester coated wire shelves Load: 110 lbs per shelf

5 polyester shelves + 10 polyester coated sliding shelves Load: 110 lbs per shelf

Forced cool air circulation

Forced cool air circulation

Forced cool air circulation

Forced cool air circulation

Forced cool air circulation

L.E.D

Fluorescent

Fluorescent

Fluorescent

Fluorescent

Fully Automatic Cycle Defrost

Fully Automatic Cycle Defrost

Fully Automatic Cycle Defrost

Fully Automatic Cycle Defrost

Fully Automatic Cycle Defrost

115V/60 Hz/3.8 kwH/Day NEMA 5-15P Plug,

115V/60 Hz/6.43 kwH/day, NEMA 5-15P Plug

115V/60 Hz/6.43kwH/day NEMA 5-15P Plug

115V/60 Hz/8.74 kwH/ Day NEMA 5-15P Plug

115V/60 Hz/8.74kwH/ Day NEMA 5-15P Plug

198.4 lbs / 90 kg

310 lbs / 142 kg

324 lbs / 142 kg

555 lbs / 252 kg

555 lbs / 252 kg

EXTERIOR DIMENSIONS W X F-B X H VOLUME WIRE SHELVES

OUTER DOORS OUTER DOOR LOCK

SHELVES & SLIDING RACKS

COOLING METHOD INTERIOR LIGHTING DEMAND DEFROSTING POWER REQUIREMENTS AND POWER CONSUMPTION NET WEIGHT

Accessories MPR-514/R-PA & MPR-1014/R-PA MODEL NUMBER MTR-C954

DESCRIPTION Temperature Recorder | 7 day, 6 inch circular chart

MPR-48B

Alarm battery back-up

LabAlertTM

Wi-Fi or Wireless Monitoring System

MPR-S313-PA MODEL NUMBER MTRC954 KM-RPPO1BB1W LabAlertTM

DESCRIPTION Temperature Recorder 7 day, 6 inch circular chart Remote Alarm Contacts with audible power failure alarm App/Cloud based Wi-Fi or Wireless Monitoring System

51

Blood Bank Refrigerators Panasonic blood bank refrigerators provide the ideal +4째C environment for safe and reliable storage of whole blood. These are designed to create stable, reliable temperature control pre-set to 4째C with precise top-to-bottom temperature uniformity. These refrigerators conform to AABB criteria with a highly efficient compressor that provides superior temperature recovery, rapid cooling, and quiet performance Models: MBR-107D(H)-PA, MBR-304GR-PA, MBR-705GR-PA, MBR-1405GR-PA SAVE

Microprocessor Control

Temperature Uniformity

Microprocessor controlled defrost system designed with thermal sensors and heaters on the evaporator, all under precise microprocessor control.

Multi air-flow plenum system ensures excellent temperature uniformity in larger capacity models. (MBR-705GR-PA, MBR-1405GR-PA).

Audible and flashing LED Visual alarms Audible and flashing LED visual alarms with remote alarm sounds, in case of power failure, high or low temperature condition, or during any thermal sensor abnormality.

Stable Temperature Control Two thermistor sensors constantly monitor the temperature in both the upper and lower part of the chamber. The sensors are located in the liquid loaded monitor bottles, which are in the shape of a blood bag to accurately simulate product temperature.

Insulated windows Insulated window prevents condensation and ensures temperature uniformity.

Interior Lamps Fluorescent interior lamp with ON/OFF switch and a large view window in the outer door provide a clear view of stored items.

52

Panasonic Healthcare Corporation of North America | Refrigerators and Freezers

MODEL NUMBER STORAGE CAPACITY, 450ML BAGS

MBR-107DH-PA

MBR-304GR-PA

MBR-705GR-PA

MBR-1405GR-PA

32

120

360

720

EXTERIOR DIMENSIONS (W X F-B X H)

15.7” x 19.5” x 59.6” 400 x 495 x 1,515mm

23.6” x 26.8” x 72.2” 600 x 680 x 1,835mm

30.3” x 32.7” x 77.0” 770 x 830 x 1,955 mm

56.7” x 32.7” x 76.8” 1,440 x 830 x 1,950mm

INTERIOR DIMENSIONS (W X F-B X H)

12.6” x 13.8” x 28” 320 x 350 x 710mm

20.5” x 19.3” x 45.3” 520 x 490 x 1,150mm

25.6 x 27.4” x 59.1” 650 x 697 x 1,500 mm

52.0” x 27.4” x 59.1” 1,320 x 697 x 1,500mm

154 lbs (70 kg)

308 lbs (140 kg)

462 lbs (210 kg)

638 lbs (290 kg)

2.8 cu. ft. (79 liters)

10.6 cu. ft. (302 liters)

21.8 cu. ft. (617 liters)

45.4 cu. ft. (1,287 liters)

NET WEIGHT EFFECTIVE CAPACITY EXTERIOR FINISH

Baked-on acrylic finish galvanized steel

INTERIOR FINISH

Stainless steel

CABINET INSULATION OUTER DOOR

Painted steel Painted steel CFC-free rigid polyurethane, foamed-in place

Triple layer glass windows

Insulated steel frame with double layer glass windows

DOOR LOCK

1

1

1

2

INNER DOOR, ACRYLIC

2

2

3

6

DRAWERS

—

5 Stainless Steel Roll-out drawers

6 Stainless Steel Roll-out drawers

12 Stainless Steel Roll-out drawers

SHELVES

3 zinc-plated steel wire and 1 stainless steel

—

—

—

110w

175w

220w

300w

HERMETICALLY SEALED COMPRESSOR REFRIGERANT

R-134a (HFC)

AIR TEMPERATURE UNIFORMITY

±1.5°C at 4°C

AIR CIRCULATION

Forced air circulation

DEFROST

Fully automatic, microprocessor controlled

TEMPERATURE CONTROL

Microprocessor control

TEMPERATURE ALARM

Factory preset at 2°C and 8°C. Fully user adjustable Audible and visual alarm (9 hours), automatic rechargeable battery (Ni-MH)

Audible and visual alarm (24 hours), automatic rechargeable battery (Ni-MH)

Visual Alarm

Audible and Visual Alarm

REMOTE ALARM CONTACT

DC30V, 1A, normal open; temperature alarm or power failure alarm

DC30V, 2A, normally open or normally closed; temperature alarm or power failure alarm

TEMPERATURE MONITOR

—

250ml x 2 product simulation probe bottles with thermistor sensor

LIGHTING, FLUORESCENT

6w

15w

1

1

POWER FAILURE ALARM DOOR ALARM

ACCESS PORT RECORDER WIRELESS MONITORING

30 days recorder

20w 2 1/7/30 day circular recorder

LabAlert Wireless App/Cloud based monitoring system

53

Undercounters Refrigerators & Freezers Designed for the demanding standards of clinical, life science, pharmaceutical, biotechnology, and industrial laboratories. The Panasonic freestanding or Under the Counter Scientific Grade Laboratory Refrigerators and Freezers feature Panasonic designed compressors and key components, stringent quality control processes. They maintain the highest quality standard laboratory appliances available today.

Models: SR-L6111W-PA, SR-L4110W-PA, SR-L4110WSEC-PA SF-L6111W-PA, HF-5017W-PA, HF-5017WSEC-PA

SAVE

Temperature Setpoint Comprehensive temperature set point with adjustable range from 1°C to 14°C, pre-set alarm at ±3ºC from temperature setpoint, monitoring based on a sophisticated microprocessor controller with digital display.

Easy Install Allows for easy installation undercounter, counter-top, or within the knee-well of laboratory cabinetry. Door shelves and standard shelving maximize product storage capacity.

Some models are stackable.

LED Display Easy to read, angled LED display and Keypad. Digital input of temperature with setpoint range from 1°C to 14°C allows end user temperature flexibility.

54

Panasonic Healthcare Corporation of North America | Refrigerators and Freezers

Specification MODEL NUMBER INTERNAL CAPACITY & VOLUME EXTERIOR DIMENSIONS (W X F-B X H) CLEARANCE REQUIREMENTS REFRIGERATION SYSTEM

SR-L6111W-PA (REFRIGERATOR)

SF-L6111W-PA (FREEZER)

6.1 cu.ft.

173 L

5.4 cu.ft.

153 L

23.6” x 34.6” x 26.2.6”* 600 x 879 x 660 mm

23.6” x 34.6” x 26.2”* 600 x 652 x 876 mm

Unit depth with hinge: 34.3”, Unit depth with hinge cap: 34.5”

Unit depth with hinge: 34.3”, Unit depth with hinge cap: 34.5”

No clearance required from top, back and sides of cabinet

No clearance required from top, back and sides of cabinet

Panasonic built compressor, R134A HFC “Green” refrigerant, and zero clearance front-breather condenser design

TEMPERATURE CONTROL

Forced air circulation with microprocessor digital input

Evaporator shelf cooling with manual defrost

TEMPERATURE SETPOINT RANGE

1°C to 14°C

-15º to -20ºC

ALARM RANGE

Tracking alarm ±3ºC around setpoint, remote alarm contacts

ACCESS PORT

13/16” (30mm) hole diameter

INTERIOR STORAGE

3 adjustable wire shelves

DOOR SWING SECURITY FEATURES

Keypad lockout feature, keyed door lock, optional padlock hasp (not included)

ELECTRICAL REQUIREMENTS WEIGHT

2 Fixed evaporator shelves Right hand hinged door swing

115V, 60Hz, NEMA 5-15 Receptacle 110 lbs.

50 kg

110 lbs.

50 kg

55

2 min

8X Faster

Condensation Management System

SafeCell UV

Touch Screen

Active Background Control

IR

IR2 Sensor

Zirconia O 2 Sensors

Sterisonic 速 H2O 2 Decontamination

InCu-saFe速 Technology

Direct Heat & Air Jacket System

LabAlertTMMonitoring Systems

Cell Culture Incubators Optimum cell growth World class design

Ideal simulated in vivo conditions Exceptional cell culture conditions

Table of Contents What to look for in an ideal incubator?

60

Panasonic Features

Which Incubator is best for you?

58

Panasonic Incubator Series Which incubator is best for you?

58

Features Overview

60

cellIQ CO2 Incubator ( 5.8 cu.ft.)

68

cellIQ Multigas Incubator ( 6.0 cu.ft.)

77

CytoGROW Optimal ( 6.0 & 7.6 cu.ft.)

83

CytoGROW Compact ( 1.7 cu.ft.)

87

CytoGROW ReachIn ( 30.1 cu.ft.)

89

TM

TM

UNIFORMITY & HUMIDITY

60

EFFICIENT CO2 RECOVERY

60

OPTIMUM 02 LEVELS

62

DECONTAMINATION FEATURES

62

CAPACITY & CUSTOMIZED INTERIORS

67

Which incubator is best for you?

cellIQ CO2 Incubators

cellIQ Multigas Incubators

CO2 Incubators | 5.8 cu.ft.

Multigas Incubators | 6.0 cu.ft.

MCO-170AICUVHL-PA

MCO-19MUVH-PA

TM

TM

IR

MCO-170AICUVL-PA

IR

OPTIONAL

IR

Next Generation CO2 Incubators New CO2 incubator design with touchscreen control panel delivers exceptional ease of use, effortless cleaning, easy maintenance, and outstanding performance with multi-level contamination control.

MCO-19MUV-PA

IR

MCO-19M-PA

IR

High performance solution for all cell culture applications The cellIQ Multigas is the industryâ&#x20AC;&#x2122;s most complete cell culture incubator for highly regulated applications like stem cell research, regenerative medicine, and in vitro fertilization (IVF).

TM

58

With a range of CO2 and multi-gas incubators, Panasonic has the right technology to meet every application, setting, and budget.

CytoGROW Optimal Series

CytoGROW Compact Series

CytoGROW ReachIn

CO2 Incubators | 6.0 & 7.6 cu.ft.

CO2 & Multigas Incubators | 1.7 cu.ft.

CO2 Incubators | 30.1 cu.ft.

MCO-18ACL-PA

MCO-5ACL-PA

MCO-80AIC-PA

OPTIONAL

OPTIONAL

IR

MCO-18ACUVL-PA

MC0-5M-PA

OPTIONAL

IR

MCO-20AIC-PA

IR

Economical with precise controls and contamination resistance CytoGrow Optimal Incubators are ideal for clinical, microbiological, and research applications.

Precise controls with space saving design allows up to 3 models to be stacked CytoGrow Compact incubators are ideal for IVF and hypoxic applications due to accurate in vitro simulation of the in vivo environment.

Greater capacity with consistent environment CytoGROW ReachIn CO2 incubator has the flexibility to grow a wide variety of cells, while providing a precise and repeatable temperature, humidity, and CO2 environment.

59

Consistent & Uniform Environment Direct Heat and Air Jacket System Technology AVAILABLE IN ALL MODELS EXCEPT IN CYTOGROW REACHIN

The patented Direct Heat and Air Jacket heating system surrounds the inner walls with a natural convection airflow. This airflow converts to radiant wall heat through thermal conduction, to achieve accurate, uniform, and highly responsive temperature control within the chamber.

Zone: Insulation

Zone: Main

Location: Side, top and rear walls, door

Location: Side, top and rear walls

Function: Promotes energy efficiency, mitigates effect of ambient temperature fluctuations on air jacket

Function: Dominant heat source Energy: Variable Microprocessor Controller: Energizes any, all or in combination of heating elements as required

Zone: Air Jacket Location: Side, top and rear walls Function: Sealed. Surrounds interior chamber with natural air convection and promotes chamber wall uniformity

Zone: Base Location: Floor Function: Base heater elevates the humidity reservoir to achieve 95% RH at 37째C

Zone: Front

Energy: Variable

Location: Outer door

Microprocessor Controller: Energizes any, all or in combination of heating elements as required

Function: Warms the inner glass in response to ambient conditions; eliminates condensation on glass and around the opening and promotes temperature uniformity Energy: Variable

The patented Direct Heat and Air Jacket heating system distributes proportional energy to the interior chamber through a natural convection air jacket surrounded by a high-density insulation to protect against ambient temperature fluctuations.

Microprocessor Controller: Energizes any, all or in combination of heating elements as required

IR

Fastest CO2 Recovery with Dual Detector IR2 Sensor Technology CELLIQTM CO2 INCUBATOR, CELLIQTM MULTIGAS INCUBATOR

The Panasonic single beam, dual detector infrared (IR2) CO2 sensor offers unprecedented control, accuracy, and stability. The IR2 Sensors provide ultra-fast recovery without overshoot and accurate CO2 averages, during periods of frequent incubator access with multiple door openings.

1

2

3

4

5

CO2 Density (%)

5%

2 min Recovery

0% Door Close

Time (min)

The Panasonic single beam, dual detector infrared CO2 system offers unprecedented control, accuracy, and stability.

60

6

Panasonic Healthcare Corporation of North America | Cell Culture Solutions

Dual detector IR2 sensor – How does it work?

Every IR sensor relies on the principal that gas will absorb light at a specific frequency. In the case of CO2, it will absorb light at 4.3μm, which is in the infra-red band of the light spectrum.

Infrared light source

Chamber Air CO2 Model

Sensor

IR radiation is directed to the sensor after passing through the filter. A filter located in front of the detector prevents wavelengths other than that specific to the measured gas from passing through to the detector. The light intensity is detected and converted into a gas concentration value.

If CO2 levels are high, fewer number of IR rays pass through | If CO2 levels are low, more IR rays pass through.

How is it different from other IR sensors?

All IR sensors need a method to calibrate the sensor periodically because light sources will drift over time and the output of the light at the desired frequency will change. This will affect the readings on the sensor so periodic readjustments are needed.

The dual detector IR2 sensor uses the same principle, but with a faster and easier process for calibration that requires no moving parts.

Single IR Sensor IR light source

The calibration is performed at regular time intervals using a separate pump, which draws in the air for a reference point and a secondary pump to circulate the chamber air through the sensor.

Filter to product light Panasonic Dual Detector IR Sensor only at 4.3μm Difference in CO2 levels do not have any effect on the second (reference) sensor absorbing light at 4.0 μm. Therefore, the calibration of the CO2 sensor can be instantly optimized using the reading from the reference source, giving timely and accurate readings without need of any pumps.

Chamber Air

Contrast wavelength IR sensor Measured wavelength: 4.0μm

CO2 measured wavelength IR sensor Measured wavelength: 4.3μm

61

Optimum O2 Levels for Multigas Incubators with Zirconia O2 Sensors AVAILABLE IN ALL MULTIGAS MODELS

Panasonic Multigas Incubators offer a non-depleting design for precise O2 control with fast response to door openings.

The maintenance-free zirconia solid-state sensor has a high degree of precision, a long service life, and does not require fine adjustment. Through accurate determination of the chamber O2 level the microprocessor injects either nitrogen gas or oxygen as required.

Proactive Contamination Control InCu-saFe® Technology AVAILABLE IN ALL MODELS

The copper-enriched stainless steel alloy interior surface (inCu-saFe®) eliminates contamination sources and mitigates the effect of airborne contaminants introduced through normal use.

Selected to provide natural germicidal protection without rust or corrosion, inCu-saFe® expresses a natural germicidal attribute to inhibit the growth of molds, fungi, mycoplasma and bacteria.

When components are removed, all interior surfaces are exposed for conventional wipe down.

Mycoplasma Survival Results MYCOPLASMA STRAIN

POSITIVE CONTROL

CONVENTIONAL TYPE 304 STAINLESS STEEL

PANASONIC InCu-SaFe®

CONVENTIONAL COPPER C1100

MYCOPLASMA FERMENTANS PG18









MYCOPLASMA ORALE CH19299









copper while maintaining both corrosion-proof and

MYCOPLASMA ARGININI G230









Type 304 stainless steel. Detailed test results are

MYCOPLASMA HOMINIS PG21









Chart summarizes test results with four strains of mycoplasma. Results demonstrate how Panasonic inCu-saFe® copper enriched stainless steel alloy offers germicidal properties of conventional C1100 discoloration-resistant properties of conventional available from Panasonic.

Mycoplasma were chosen for this study because they are the smallest organisms that are most responsible for contamination in a laboratory.

Traditional methods of contamination control, such as heat or HEPA filters, do not prevent mycoplasma growth.

InCu-saFe® INTERIORS InCu-saFe fights off surface contamination and does not corrode like solid copper surfaces ®

Easier visibility with better looking interior Standard feature with Panasonic Incubators at no additional cost

62

PURE COPPER INTERIORS Will corrode over time (humid environment turns it into green cupric oxide, which may prove to be lethal to cells) Contamination difficult to detect due to less visibility More expensive and difficult to maintain

Panasonic Healthcare Corporation of North America | Cell Culture Solutions

SafeCell UV Technology CELLIQTM CO2 INCUBATOR, CELLIQTM MULTIGAS (MCO-19MUV-PA, MCO-19M-UVH-PA), CYTOGROW OPTIMAL (MCO-18ACUVL-PA, MCO-20AIC-PA) CYTOGROW COMPACT (OPTIONAL IN MCO-5ACL-PA, MCO-5M-PA), CYTOGROW REACHIN (OPTIONAL MCO-80IC-PA)

1.0E+06

1.0E+05

1.0E+05

1.0E+05

1.0E+04

1.0E+04 1.0E+03 1.0E+02 1.0E+01 1.0E+00 0

1

2

3

4

5

6

7

8

Survival Number (CFU/ml)

1.0E+06 Survival Number (CFU/ml)

Survival Number (CFU/ml)

Patented SafeCell UV technology uses a programmable ultraviolet lamp that sterilizes air and humidity water pan without affecting the cell cultures. SafeCell UV inhibits the growth of mycoplasma, bacteria, molds, spores, viruses, yeasts and fungi without costly HEPA filter air scrubbers, which accumulate contaminants in the filter media. HEPA filters are also ineffective on particles less than 0.3 microns.

1.0E+04 1.0E+03 1.0E+02 1.0E+01 1.0E+00

9 10

0

1

2

3

4

5

6

7

8

1.0E+03 1.0E+02 1.0E+01 1.0E+00

9 10

0

UV Exposed Time (Min.) (S.Aureus: ATCC 8538P)

UV Exposed Time (Min.) (E.Coli: ATCC 8739)

1

2

3

4

5

6

7

8

9 10

UV Exposed Time (Min.) (B.Stearo: ATCC 7953)

E. coli Survival Graph

S. aureus Survival Graph

B. stearothermophilus Survival Graph

Results, 48 Hours, E. coli

Results, 48 Hours, S. aureus

Results, 24 Hours, B. stearothermophilus

3 x 109 cells, 3 liters = 1 x 106 ml Culture plate array shows 48 hour 37°C cultures of humidity pan water with E. coli bacteria (Source ATCC8739) following exposure to SafeCell UV light for 0, 1, 3 and 5 minutes.

3 x 109 cells, 3 liters = 1 x 106 ml Culture plate array shows 48 hour 37°C cultures of humidity pan water with S. aureus bacteria (Source ATCC6538P) following exposure to SafeCell UV light for 0, 1, 3 and 5 minutes.

5 x 107 cells, 2 liters = 2.5 x 104 ml Culture plate array shows 24 hour 55°C cultures of humidity pan water with B. stearothermophilus bacteria (Source IFO13737, equivalent to ATCC7953) following exposure to SafeCell UV light for 0, 1, 3 and 5 minutes.

SafeCell UV’s anti-germicidal effects in comparison to high heat decontamination process for competitor brands.

UV Panasonic

UV

HIGH HEAT Brand F (140°C)

Brand H (90°C)

TEST RESULTS, MAXIMUM LOG REDUCTION BACTERIA

>4.5

>4.5

>4.5

YEAST

>2.9

>2.9

>2.9

MOLD

>2.7

>2.7

>2.7







VIS

IR

Efficiency %

METHOD

Unlike typical germicidal lamps, the long-life SafeCell UV lamp is designed to deliver straight line performance at 253.7nm for maximum germicidal efficiency and long life span.

DECONTAMINATION OPTIONS OVERNIGHT ACTIVE BACKGROUND CONTAMINATION CONTROL







Wave Length (nm) The SafeCell UV lamp is a highly effective, ozone-free contamination control technique.

Panasonic Lamp

Ozone Release

Germicidal Effect

Eye Sensitivity

Sunlight

63

SafeCell UV – Versatile Program Cycles for Optimum Usability

OFF

After H2O2 Vaporization

After Door Openings

24 Hour UV Decontamination

The UV lamp automatically cycles ON for up to 90 minutes following the ten minute H2O2 vapor cycle, reducing the H2O2 to water droplets. These droplets automatically condense onto the interior floor for easy wipe-up.

The UV lamp automatically turns ON for 5 minutes after the door is closed, which decontaminates incoming external air.

This feature is useful for overnight decontamination, before first use, between patient protocols, or following total chamber cleaning after maintenance or service.

OFF If UV protection is not desired, SafeCell UV lamp can be turned OFF through the touch panel control.

Active Background Contamination Control CELLIQTM CO2 INUBATOR , CELLIQTM MULTIGAS INUBATOR (MCO-19M-UV-PA, MCO-19M-UVH-PA), CYTOGROW OPTIMAL (MCO-18ACUVL-PA, MCO-20AIC-PA) CYTOGROW COMPACT (OPTIONAL IN MCO-5ACL-PA, MCO-5M-PA), CYTOGROW REACHIN (OPTIONAL MCO-80IC-PA)

Together with the passive resistance of InCu-saFe® (copper-enriched stainless steel technology) and SafeCell UV Technology (decontamination control airborne contaminants in situ) forms an effective Active Background Contamination Control unique to the Panasonic incubator. As the cell culture process take place in the incubator chamber, the work of germicidal protection from airborne organisms continues unabated without costly downtime or harm to the cultured cells. This contamination control extends to thermophilic organisms.

Airflow

During normal day-to-day operations, when cells are incubated within the chamber, the UV lamp is visibly isolated from the cell culture chamber by a plenum cover over the humidity pan. Humidified air and surface water, in the humidity pan, is decontaminated without damaging the cells.

UV Light

ACTIVE BACKGROUND CONTAMINATION CONTROL

TRADITIONAL CONTAMINATION CONTROL METHODS

No additional stress on incubator components like that with Heat incubators

Every heat cycle adds to the incubator component stress, takes a long time to complete, requires all of the components to be removed and does not guarantee complete decontamination from organisms like thermophilic bacteria

Continuously provides germicidal protection without any costly downtime The position of the UV lamp, inCu-saFe® interiors and the relationship between the UV lamp, plenum, humidity reservoir and airflow system is integral to the performance of the Panasonic incubator for giving optimum continuous protection

64

HEPA filters will not work on contaminants below 0.3 microns - this includes viral and bacterial contaminants like mycoplasmas HEPA filters used in biological safety cabinets are tested for leaks and certified whereas, the disposable filters used in the incubators are not guaranteed to be leak proof

Panasonic Healthcare Corporation of North America | Cell Culture Solutions

Reactive Contamination Control Sterisonic® H2O2 Decontamination Technology CELLIQTM CO2 INCUBATOR (MCO-170AICUVHL-PA), CELLIQTM MULTIGAS (MCO-19M-UVH-PA)

Unlike conventional incubators, Panasonic incubators permit use of the H2O2 process in situ with complete safety, zero impact on the surrounding lab environment, and shorter downtime.

For GMP and regulated environments, minor contamination can prove to be a major constraint for completing an important research protocol. In such environments, where time and money are extremely imperative to overall success of research projects, contamination leads to significant loss of valuable resources (cells, culture vessels, media and sera etc.) as well as wasted effort spent developing cultures and setting up experiments.

Major contaminants found in Laboratory environment include • easy to detect - bacteria, molds and yeast • difficult to detect – viruses and mycoplasma

Smallest free living organism (0.2-0.3μm).

Approximately 180 different species exist.

Most common form of cell culture contaminant: 15% in US.

Mycoplasma Contamination No Cell wall – cannot be seen under phase contrast microscopy.

Affects virtually every aspect of cell behavior and growth, even gene expression.

(11 - 15% of cell culture samples have been found to be contaminated with mycoplasma according to the studies conducted by FDA)

Increased decontamination efficiency and efficacy An independent study was conducted to evaluate the effectiveness of H2O2 decontamination against high heat decontamination. Five different variety of organisms were chosen for this study:

MICROBE

Mycoplasma orale

Staphylococcus aureus

Acholeplasma laidlawii

Candida albicans

Bacillus subtilis

TYPE

OXYGEN REQUIREMENTS

GRAM REACTION/ CELL MORPHOLOGY

PHYSIO-CHEMICAL RESISTANCE

Bacteria

Facultative anaerobe

Gram Negative/ Micrococcal

High

Can persist without causing cell death, while altering the behavior and metabolism of the host cells.

Facultative anaerobe

Gram Positive/ Cocci

Low

Forms biofilms that may be more difficult to kill.

Bacteria

Facultative anaerobe

Gram Negative/ Micrococcal

Medium

Another member of Class Mollicutes that are very difficult to detect and can affect cell cultures similar to Mycoplasma orale.

Fungi

Facultative anaerobe

Yeast/ Filamentous

Low

Grows as yeast as well as filamentous cells. Can form biofilms and are resistant to disinfectants.

High

Can form endospore that can tolerate extreme environmental conditions such as high heat temperatures, extreme pH, radiation, etc.

Bacteria

Bacteria

Obligate aerobe

Decontamination Time

Gram Positive/ Rod

Brand B

Inoculum Delivered

Brand A Panasonic 3hrs

12hrs

24hrs

CONTAMINATION CHARACTERISTICS

Result An independent study demonstrates that Sterisonic® H2O2 Decontamination technology provides 100% kill rate with at least 6 log reduction of major contaminants within 3 hours, making it more efficient than conventional heat decontamination.

65

Sterisonic® H2O2 Decontamination provided 100% kill rate with at least 6 log reduction of all the tested organisms within 3 hours, making it more efficient than heat decontamination.

HARMLESS

Sa

SafeCell UV

H2O + O2 e feC

Remaining H2O2 and hydroxyl radicals

ll UV

DNA

DAMAGE

AGE AM

AGE AM

C EL L D

CONTAMINANT

DEATH

C EL L D

2•OH

vir en al rn nte le i tab Uns

H2O2 separates in two hydroxyl radicals

on m

•OH + OHH2O2 can obtain an efrom an organic source

en

t

CONTAMINANT

How does it work?

Hydrogen peroxide starts in aqueous form and is converted to vapor using high frequency ultrasonics, which accesses every point of the chamber. During this process, the blower motor remains active while the air flow travels. Following the decontamination period, the H2O2 is irradiated with ultraviolet light (UV). This results in the breakdown of hydrogen peroxide into •OH free radicals, as illustrated in the diagram.

•OH initiates chain reaction of electron stealing

Decontamination Cycle

High Heat Decontamination

Sterisonic H2O2 Decontamination Technology STEP 1

STEP 3

90

MIN

MIN

Prep Time: 5 min

Resolve: 90 min

Empty contents of humidity pan. Then place pan and pan cover on shelves in chamber.

UV lamp glows for 90 minutes reducing H2O2 to harmless water droplets can be easily wiped with a sterile cloth.

STEP 4

STEP 2

30 MIN

H2O2

Start Cycle: 30 min.

Chamber warms to 45˚C (optimum H2O2 vaporization temperature). H2O2 Atomizer creates vapor, which is circulated throughout chamber by interior blower.

66

3

HRS Cycle: Finish Refill the humidity pan and return humidity pan and plenum to operating position.

MIN

Prep Time: 15 min Remove interior components sensitive to high heat.

90 MIN

Start Cycle: 90 min Interior chamber elevates to high heat.

14

HRS

Decontaminate: 14 hours Interior chamber elevates to high heat.

24

HRS

Finish.

Incubator must cool from high heat temperatures to near ambient.

Panasonic Healthcare Corporation of North America | Cell Culture Solutions

Accelerate Your Growth

with increased capacity and customized interiors With reversible inner and outer doors, Panasonic incubator offers the industry’s most flexible installation options available.

Space efficient inventory management is simplified through a system of adjustable and extendable shelves.

Brand A

Brand A

cellIQ

TM

CO2 Incubator Optional 4 inner doors Brand A

Brand A

54

Allows for storing 5 lines of 100mm dishes.

Allows for storing 5 lines of T-75 flasks.

3- Layer Multi-Flasks

Multiple chamber inner doors minimize loss of balanced interior atmosphere during routine door openings. Available on selected models.

ROI on Incubation: CHO-M1

EcoPack 2-293

Total Expected Yield

Total Expected Yield

Total Expected Yield

6

6

9

2 0

Panasonic

4 2 0

Brand A

Brand B

UP TO 50% MORE

4

Panasonic

6 3 0

Brand A

Brand B

• Incubator, filled to capacity with 3-layer BD Falcon™ Multi-Flasks. Based on 1 incubation cycle.

UP TO 50% MORE

12 Cells/cm2 x 109

8 Cells/cm2 x 109

8 UP TO 50% MORE

Cells/cm2 x 109

BHK-21

Panasonic

Expected yield figures based on expected yield per sq.ft. of surface area times the maximum total cell growth surface area able to fit in each incubator.

“Brand A” Capacity: 6.5 cu.ft.; “Brand B” Capacity: 5.3 cu.ft.; Panasonic Sterisonic Capacity: 6.0 cu.ft.

Brand A

Brand B

67

cellIQ

TM

INTELLIGENT CO2 INCUBATOR

Smart TOUCH SCREEN INTERFACE

2min CO2 RECOVERY

8x Faster DECONTAMINATION

Rethink cell growth.

Empower your cell culture through the most advanced user interface and technology. Optimize your environment with a new intelligent touch screen for uniform temperature control, precise CO2 recovery, and rapid decontamination.

Learn more at us.panasonic-healthcare.com/celliqseries

cellIQ

TM

The Next Generation of CO2 Incubators Models: MCO-170AICUVL-PA / MCO-170AICUVHL-PA

Capacity: 5.8 cu.ft.

Panasonic’s cellIQ CO2 incubator with a touchscreen control panel delivers improved usability, rapid cleaning, and effortless maintenance while keeping its tradition of outstanding environmental stability and precision performance.

TM

IR

Applications Stem cell research

Low volume media micro-plate work

Autologous tissue regeneration

Esoteric plant and amphibian cell culture

Genomic and proteomic expression

Hyper-sensitive and transgenic cell culture

cellIQ CO2 Incubator TM

Optimized for high-value samples including hard-to-grow cell lines and contamination-sensitive media/reagents.

Touch Screen

Easy Clean

Condensation Management System

cellIQ offers integrated shelf brack-

A color LCD touch panel delivers full

It uses a unique antibacterial coated

ets with minimal interior component

control over different parameters.

‘dew stick’ cooled by peltier cooling

that makes it easier to clean and

Control can be performed with gloved

technology that acts similar to a glass

maintain.

fingers.

of cold water on a humid day. The con-

TM

densed water droplets then fall back harmlessly into the humidity pan.

No claim is made to the exclusive right to use ‘Cell” apart from mark as shown.

69

cellIQ CO2 Incubator TM

PRECISION METRICS

2min CO2 RECOVERY

IR

Stable pH & cellular conditions

Temperature Uniformity with Direct Heat and Air Jacket System

CO2 Recovery within 2 Minutes with Dual Detector IR2 Sensor 1

2

3

4

5

20%

Stable Internal Environment

6

Full Temperature Recovery Point

38

5% Temperature (°C)

CO2 Density (%)

36 35 34 33 32 0

0%

10

20 Time (min.)

Door Close

Greater yield Shelf channels are now an integral part of the chamber, opening up more space for trays and allowing the incubator to accommodate more culture containers.

37

2 min Recovery

MORE CAPACITY

30

40

Allows for 5 lines of storage of 100mm dishes

Allows for storing 5 lines of T-75 flasks.

Time (min)

Prevent Microbial Contamination Active Background Control with inCu-saFeÂŽ and SafeCell UV Airflow

UV Light

70

Panasonic Healthcare Corporation of North America | Cell Culture Solutions

Panasonic incubators are extensively tested to meet the toughest quality standards in the world for performance, ergonomics, and cost of ownership.

80% TIME SAVINGS

Easy to maintain CellIQTM offers integrated shelf channels with minimal interior components that make it easier to clean and maintain.

cellIQ

TM

Traditional

Easy to use LCD Touch Panel Controller & USB Data Logging A color LCD touch panel delivers full control over different protocols. Touch panel can be controlled with gloved fingers since the touch panel has resistive coating.

8x Faster CONTAMINATION CONTROL With Sterisonic速 H2O2 Decontamination Technology provides 100% contaminant kill rate Decontamination Time Inoculum Delivered

Brand B

Brand A Panasonic 3hrs

12hrs

24hrs

71

Heating indicator

1

Lamp lights when the heater is energized.

5

6

1

9

2

2

Temperature Display

3

Message display field:

4

UV Lamp condition display

5

CO2 gas injection indicator:

Alarms, errors or messages are displayed when the fault occurs.

10

4 3

8 7

The lamp lights when CO2 gas is being injected.

LCD Touch Panel Controller

6

CO2 gas supply indicator and select key

7

USB Log Port

8

H2O2 Decontamination Key

9

The current chamber CO2 level is displayed

A color LCD touch panel delivers full control over different protocols. Control can be performed with gloved fingers.

USB Log Function Standard USB port provided for convenient log data transfer to a USB memory stick and to a PC. Data log period is 1.5 months using 2-minute intervals.

Acquisition Data Parameters Chamber temperature

Alarm

CO2 level

CSV (Excel) file output

Door opening/closing

Time and date stamp

Menu Screen

Temperature Graphing Screen

The Menu Screen allows for alarm settings. Data logs and all other incubator settings.

The system allows for recording the logs of the actual temperature, CO2 levels, and the door openings of the chamber.

10

Outer door (opening / closing display)

Maximum Security Control with Electric Lock* cellIQ CO2 Incubator with Sterisonic H2O2 Decontamination offers a standard feature of automatic door locking with one to six digit password protection that can be set up for releasing the lock.

TM

*(Optional on MCO-170AICUVL-PA Model)

72

80% Less Time Spent Cleaning The cellIQ CO2 Incubator has less removable parts with its new interior design making it easier to clean and maintain.

TM

Easy Clean cellIQ offers integrated shelf channels with minimal interior components that make it easier to clean and maintain.

TM

Decontamination Time Comparison

Traditional

cellIQ

TM

3

HRS

cellIQ with Sterisonic® H2O2 Decontamination

CO2 INCUBATOR

TM

INCUBATOR

The unit is ready to accept cultures 3 hours after decontamination starts.

High Heat Decontamination

24

Maximum time required for decontamination above 150°C.

HRS

Precision Metrics Humidity Recovery characteristic Full Humidity Recovery Point

60 Door opening 30 sec.

40

Door opening 60 sec.

20

37 36

34

Door opening 30 sec.

33

Door opening 60 sec.

20

0%

35

32 0

10

20 Time (min.)

30

0

10

Time (min.)

2

3

4

5

5% CO2 Density (%)

80

CO2 level recovery characteristics 1

Full Temperature Recovery Point

38 Temperature (°C)

100 Humidity (%) RH

Temperature Recovery characteristics

30

2 min Recovery Door Close

Time (min)

73

SafeCell UV Decontamination Decontamination of airborne contaminants following door opening The new 5000 Hour UV Lamp provides long term maintenance-free service without the production of Ozone.

Active Background control is provided by automatically turning on the UV Lamp following door openings effectively destroying airborne contaminants in the air system while not exposing cultures.

UV Lamp also provides easy access to an effective 24 hour chamber decontamination feature through the Touch Panel.

Condensation Management System It uses a unique antibacterial coated â&#x20AC;&#x2DC;dew stickâ&#x20AC;&#x2122; cooled by peltier cooling technology. This acts similar to a glass of cold water on a humid day.

The condensed water droplets then fall back harmlessly into the humidity pan.

The temperature of the dew stick is controlled electronically by monitoring ambient conditions

Integrated Shelf Channels Shelf Channels are now an integral part of the chamber, opening up more space for trays, allowing storage of more cell culture containers.

Allows for storing 5 lines of 100mm dishes.

74

to affect the temperature of the dew stick.

Thus, we can provide a high humidity environment without any unwanted condensation in the chamber and resulting contamination concerns.

Allows for storing 5 lines of T-75 flasks.

Panasonic Healthcare Corporation of North America | Cell Culture Solutions

cellIQ CO2 Incubator

Traditional

TM

TEMPERATURE UNIFORMITY Direct Heat and Air Jacket

Water Jacket

Patented Direct Heat and Air Jacket System for improved uniformity - ±0.25 at 37°C.

Water Jacket Incubator is using an older technology and it can be a source of contamination.

Water Jacket incubators are also difficult to move.

INTERIOR InCu-saFe® - Copper enriched stainless

Stainless Steel does not inhibit contamination

fights off surface contamination and doesn’t corrode like solid copper surfaces. This is a standard feature (surface) with no additional cost.

Copper has similar germicidal properties as inCu-saFe®, but is more expensive and difficult to maintain as well as it is corrosive over time.

CO2 SENSORS 1

CO2 Density (%)

5%

2

3

4

5

6

2 min Recovery

0% Door Close

Panasonic single beam, Dual Detector Infrared (IR2) Sensors offer full CO2 recovery within 2 minutes, without overshoot following the door openings.

Time (min)

!

Inefficient Recovery Unwanted changes

Single Detector IR Sensor Inefficient CO2 recovery within the chamber. This leads to unwanted changes in the pH and consequently undesired changes in the cell culture. Other IR sensors use an incandescent light bulb with shorter life span.

MAJOR CONTAMINATION CONTROL METHODS Sterisonic® H2O2 Decontamination reduces contamination within 3 hours with at least 6 log reduction and 100% kill rate.

SafeCell UV along with inCu-saFe® provides active background contamination control.

HEPA filters typically will not collect all contaminants as many are below 0.3μm in size.

High heat decontamination takes up to 24 hrs and does not guarantee complete sterilization of thermophilic organisms.

High heat decontamination will possibly generate volatile organic compounds which can be detrimental to cell growth.

75

Specifications MODEL

MCO-170AICUVL-PA

MCO-170AICUVHL-PA

UV ACTIVE BACKGROUND CONTAMINATION CONTROL

Standard

Standard

TOUCH PANEL (WVGA FULL COLOR LCD)

Standard

Standard

USB DATA LOGGING

Standard

Standard

H2O2 DECONTAMINATION SYSTEM

Optional

Standard

24 HOUR UV DECONTAMINATION SYSTEM

Standard

Standard

SAFECELL UV SYSTEM

Standard

Standard

INCU-SAFE® COPPER-ENRICHED STAINLESS INTERIOR

Standard

Standard

SINGLE BEAM, DUAL DETECTOR IR CO2 SENSOR

Standard

Standard

DIRECT HEAT & AIR JACKET (DHA) HEATING SYSTEM

Standard

Standard

ENVIRONMENTAL PERFORMANCE TEMPERATURE CONTROL RANGE

+5OC above ambient to 50OC (Ambient temperature: 5OC - 35OC)

TEMPERATURE CONTROL UNIFORMITY

±0.25OC (23OC ambient, setting: 37OC, CO2: 5%, no load)

CO2 CONTROL RANGE AND DEVIATION

0% to 20% / ±0.15% (23OC ambient, setting 37OC, 5% CO2, no load)

CO2 SENSOR PLATFORM CO2 SAMPLING, PATENT PENDING CO2 CALIBRATION AIRFLOW INTERIOR HUMIDITY

Ceramic light source, single beam infrared sensor, with dual wavelength measurement for continuous auto-zero calibration No moving parts/no air pumps. Airflow maintained via pressure difference Automatic, continuous zero reference calibration. Optional semi-automatic one point gas calibration system Gentle vertical airflow, continuous with inner door closed 95% ±5%R.H. at 37OC by natural evaporation with humidifying pan. Adjustable

CONTROL, MONITORING, ALARM TEMPERATURE AND CO2 CONTROL

P.I.D. control system setpoint resolution 0.1OC, 0.1%

DATA ACQUISITION

Automatic log function of temperature, CO2, Door opening/closing, Alarm and CSV (Excel) file output.

USB data collection

COMMUNICATION

Remote alarm contacts standard. Optional LabAlert wireless monitoring system.

CABINET DESIGN AND CONSTRUCTION EXTERIOR CABINET AND DOOR INTERIOR AND SHELVES

Galvanized steel with powder coat finish Copper-enriched stainless steel

INNER DOOR

Tempered glass

INSULATION

Extruded Polystyrene

OUTER DOOR

Heated and field reversible

ACCESS PORT

Diameter 30mm port with non-VOC silicone stoppers

LEVELING FEET

4, Adjustable

ENERGY AND CO2 UTILITIES MAXIMUM POWER CONSUMPTION MAXIMUM HEAT DISCHARGE CO2 GAS CONNECTION CO2 GAS PRESSURE

376W 1014 BTU/hr (1070 KJ/h) 4mm to 6mm inner diameter tubing 0.03 Mpa (G) (0.3kgf/cm2G, 4.3psiG) from two stage CO2 regulator

DIMENSIONS, WEIGHTS, CAPACITIES INTERIOR DIMENSIONS ( W X D X H )

490 x 523 x 665 (mm) /19.3 x 20.6 x 26.2 (inch)

EXTERIOR DIMENSIONS (W X D X H)

620 x 710 x 900 (mm) / 24.4 x 28.0 x 35.4 (inch)

VOLUME

165 liters (5.8 cu.Ft.)

SHELVES

4 supplied as standard (Maximum 10), 470 (W) x 450 (D) x 12 (H) mm, Maximum load 7kg/shelf (15lbs)

NET WEIGHT VOLTAGE

76

80kg (176 lbs) 110-120V, 60Hz

Panasonic Healthcare Corporation of North America | Cell Culture Solutions

cellIQ

TM

Multigas Incubators

The industryâ&#x20AC;&#x2122;s most complete cell culture solution for highly regulated applications or conventional incubation. Now with safe, effective, and documented 3 hour in situ SterisonicÂŽ H2O2 Decontamination for the fastest turn-around and maximum availability.

Models: MCO-19M-PA, MCO-19MUV-PA,

MCO-19MUVH-PA Capacity: 6.0 cu.ft.

IR

Applications Stem cell research Autologous tissue regeneration Regenerative medicine In vitro fertilization research Any sensitive and hard-to-grow cell line culture

MCO-19M-PA MCO-19MUV-PA MCO-19MUVH-PA

Multigas Incubators

The Stanford Study – Growth at Physiological Oxygen provides “in vivo” environment for culturing Mesenchymal Stem Cells.

IMPORTANCE OF PHYSIOLOGICAL O2 FOR MESENCHYMAL STEM CELLS Phase contrast pictures of BM-MSC show typical bipolar morphology

Total BM-MSC recovered per passage is higher at PhysOx (5%O2) as compared to AtmosOx (20%O2)

physOx

atmosOx 0.00E+00

1.00E+06

2.00E+06

3.00E+06

Cells recovered after culture for 3 days

* Growth at Physiological Oxygen provides “in vivo” environment

Precision Metrics

for culturing Mesenchymal Stem Cells

CO2 level recovery characteristics 1

2

3

4

Sterisonic H2O2 Decontamination Metrics 5

6 Decontamination Time

CO2 Density (%)

5%

2 min Recovery

Brand A Panasonic 3hrs

Door Close

12hrs

Time (min)

Increased Efficiency – Time saved in a year

78 hrs

cellIQ Featured Decontamination Technologies TM

SafeCell UV

Sterilization time Panasonic 3hrs

624 hrs

Brand B

Inoculum Delivered

0%

InCu-saFe® Active Background (Preventative)

Other up to 24hrs Assuming that decontamination cycles are run every two weeks as per GMP requirements.

78

A study by Atkuri et al.* involved culturing Bone Marrow derived Mesenchymal stem cells (BMMSC) in a BD Mosaic hMSC Serum free cell culture environment at either physiological (5%) O2 or atmospheric oxygen (20%) O2 levels in tri-gas incubators (Panasonic Healthcare Corporation). One of the major findings was that human BM MSCs grow approximately 30-50% faster at physiological oxygen.

Sterisonic H2O2 Decontamination

24hrs

Control and Monitoring

Panasonic Healthcare Corporation of North America | Cell Culture Solutions

Intelligent interface through integrated LCD control with graphical displayâ&#x20AC;&#x201D; The cellIQ incubator is managed TM

by an integrated micro-processor controller with LCD graphical display to simplify all incubator functions.

Stable temperature and humidity conditions are achieved through a combination of performance systems supervised by the controller complete with alarm, programming, calibration, and diagnostic protocols.

3. UV Resolution:

1 1. Start Cycle: When the H2O2 button is pressed a confirming message prompts the user to proceed with the decontamination cycle or cancel.

2

2. H2O2 Vapor Cycle: Once the door locks automatically, the cycle starts. The flashing H2O2 display confirms the process and counts down remaining H2O2 vaporization time.

3

4

Message display | Digital alphanumeric LCD | Pop-up menu

Visual alarm H2O2 decontamination sequence start key

Menu call button

Positive feedback tactile input buttons

Positive feedback tactile entry and function keys

The H2O2 atomizer automatically completes after a 10 minute cycle. UV lamp comes ON. The flashing UV Resolve display counts down remaining time in the UV cycle as H2O2 is reduced to water and trace oxygen.

4. Cycle Complete: Complete the door lock releases automatically.

The H2O2 atomizer and cable can be disconnected and removed and all interior components restored to their normal position.

cellIQ – CO2 /O2 Incubators TM

MODEL

MCO-19MUVH-PA

MCO-19MUV-PA

MCO-19M-PA

H2 O 2 DECONTAMINATION SYSTEM

Standard

Optional

Optional

SAFECELL UV SYSTEM

Standard

Standard

Optional

SINGLE BEAM, DUAL DETECTOR IR CO 2 SENSOR

Standard

Standard

Standard

INCU-SAFE® COPPER ENRICHED STAINLESS STEEL INTERIOR

Standard

Standard

Standard

LCD GRAPHICAL CONTROLLER/DISPLAY, DOOR MOUNTED

Standard

Standard

Standard

DIRECT HEAT, AIR (DHA) AIR JACKET

Standard

Standard

Standard

MAJOR OPERATING SYSTEMS

DECONTAMINATION Vaporization in situ

Optional

Optional

INTERIOR UV LAMP, PROGRAMMABLE, OZONE FREE

Standard

Standard

Optional

COPPER ENRICHED STAINLESS STEEL INTERIOR WITH GERMICIDAL PROTECTION

Standard

Standard

Standard

H2 O 2 DECONTAMINATION SYSTEM

ENVIRONMENTAL PERFORMANCE TEMPERATURE CONTROL RANGE TEMPERATURE CONTROL UNIFORMITY DEVIATION CO 2 CONTROL RANGE AND DEVIATION CO 2 SENSOR PLATFORM CO 2 CALIBRATION AIRFLOW INTERIOR HUMIDITY

+5ºC above ambient to 50°C ±0.25ºC (in 25ºC ambient, setting 37ºC, 5% CO 2 , no load) 0% to 20%, ±0.15% in 25ºC ambient, setting 37ºC, 5% CO 2 , no load Ceramic based, single beam, dual wavelength measurement of actual vs. contrast, with continuous auto-zero calibration.

Single point zero automatic; semi-automatic one point span (reference optional).

Gentle vertical airflow, continuous with inner door closed.

95%RH at 37°C through evaporation via DHA heating system; reflective optical low water sensor.

CONTROL, MONITORING, ALARM LABALERT MONITORING TEMPERATURE AND CO 2 CONTROL DISPLAY DATA ACQUISITION

Optional P.I.D., setpoint resolution 0.1% and 0.1°C Alphanumeric LCD digital display messaging.

Data Acquisition Automatic log function of temperature and CO 2 .

CABINET DESIGN AND CONSTRUCTION INTERIOR, SHELVES INNER DOOR

Tempered glass / 4 separate, gasketed inner doors, tempered glass

INSULATION

Rigid foam polyurethane.

OUTER DOOR

Reversible, heated.

ACCESS PORT

Single opening with interior and exterior 1.18" (30 mm) silicone stoppers.

LEVELING FEET

80

4, Copper-enriched stainless steel / 3, Copper-enriched stainless steel

4, adjustable.

Panasonic Healthcare Corporation of North America | Cell Culture Solutions

cellIQ –Energy, Electrical and Utilities TM

MCO-19M-PA MCO-19MUV-PA MCO-19MUVH-PA

MODEL MAXIMUM POWER CONSUMPTION

354W

MAXIMUM HEAT DISCHARGE ELECTRICAL CONNECTION

1062 BTU/HR 115V,60Hz, 1 phase, NEMA 5-15P plug provided;

CO 2 GAS CONNECTION CO 2 GAS INPUT PRESSURE

¼" Barb Fitting Nominal 5 psi from two-stage CO 2 regulator

CO 2 GAS CYLINDER SWITCHOVER SYSTEM O2 CONTROL SYSTEM O2 RANGE AND VARIATION N2 /O2 INLET CONNECT/PRESSURE

Optional Microprocessor P.I.D, Zirconia Sensor 1-18%, 22-80%,±0.2% in 25ºC ambient, setting 37ºC, 5% CO 2 , 5% O 2 , no load Nominal 7 psi from two-stage regulator

N2 /O2 SWITCHOVER SYSTEM

Standard

cellIQ –Dimensions, Weights and Capacities TM

MODEL MCO-19M-PA MCO-19MUV-PA MCO-19MUVH-PA

VOLUME (CU.FT.)

EXTERIOR DIMENSIONS (W X F-B X H)

INTERIOR DIMENSIONS (W X F-B X H)

SHELVES

NET WEIGHT (NOMINAL)

5.72

24.4" x 27.9" x 35.4" 620 x 710 x 900 mm

19.3" x 20.6" x 26.2" 490 x 523 x 665 mm

15 max / 4 supplied std.

17.7" x 17.7" (15.4 lbs capacity) 450 x 450 mm (7 kg capacity)

207.2 lbs 94 kg

162 L

cellIQ –Series Energy, Electrical and Utilities TM

MODEL

MAXIMUM POWER CONSUMPTION MAXIMUM HEAT DISCHARGE ELECTRICAL CONNECTION CO 2 GAS CONNECTION CO 2 GAS INPUT PRESSURE CO 2 GAS CYLINDER SWITCHOVER SYSTEM

MCO-19M-PA MCO-19MUV-PA MCO-19MUVH-PA 310W 1062 BTU/HR 115V,60Hz, 1 phase, NEMA 5-15P plug provided; ¼" Barb Fitting Nominal 5 psi from two-stage CO 2 regulator Optional

O2 CONTROL SYSTEM

N/A

O2 RANGE AND VARIATION

N/A

N2 /O2 INLET CONNECT/PRESSURE

N/A

N2 /O2 SWITCHOVER SYSTEM

N/A

81

cellIQ –Series Accessories TM

Panasonic Biomedical products include a broad range of accessories to meet specific application requirements.

For accessories or options not listed herein, contact Panasonic or your authorized Panasonic sales representative.

MODEL

MCO-19M-PA

MCO-19MUV-PA

MCO-19MUVH-PA

Catalog No.

Catalog No.

Catalog No.

H2 O 2 DECONTAMINATION KIT

N/A

MCO-HL-PA

Built-in

H2 O 2 VAPOR ATOMIZER

N/A

N/A

MCO-HP-PW

H2 O 2 REAGENT (FORMULATED FOR PANASONIC CELLIQTM )

N/A

N/A

MCO-H2O2-PV

MCO-21GC-PW

MCO-21GC-PW

MCO-21GC-PW

MCO-SG-PW

MCO-SG-PW

MCO-SG-PW

MCO 100L

MCO-100L

MCO-100L

AUTOMATIC CO 2 CYLINDER SWITCHOVER SYSTEM GAS CALIBRATION SYSTEM, SEMI-AUTOMATIC ONE POINT CALIBRATION FUNCTION CO 2 CYLINDER REGULATOR, CGA FITTING 320 ROLLER BASE. FOR USE IN SINGLE OR STACKED INSTALLATIONS

MCO-18RB-PW

MCO-18RB-PW

MCO-18RB-PW

INCU-SAFE® SHELF AND BRACKETS. INCLUDES TWO SHELF BRACKETS. FULL SHELF

MCO-47ST-PW

MCO-47ST-PW

MCO-47ST-PW

INCU-SAFE® HALF TRAY SYSTEM

MCO-25ST-PW

MCO-25ST-PW

MCO-25ST-PW

MCO-CL

MCO-CL

MCO-CL

COMMUNICATIONS PORT. LOCATED AT REAR OF CHAMBER, ANALOG 4-20MA

MCO-420MA-PW

MCO-420MA-PW

MCO-420MA-PW

SAFECELL UV SYSTEM KIT NARROW-BANDWIDTH 253.7NM LAMP AND ASSEMBLY

MCO-19UVS-PA

Built-In

Built-In

N2 CYLINDER REGULATOR, CGA FITTING 580 (FOR LOW OXYGEN APPLICATIONS)

MCO100N

MCO100N

MCO100N

O2 CYLINDER REGULATOR, CGA FITTING 540 (FOR HIGH OXYGEN APPLICATIONS)

Y12200A540

Y12200A540

Y12200A540

INTEGRATED COOLING OPTION

+50ºC

+50ºC

With Cooling Coil

Without Cooling Coil +5ºC over

+18ºC

H2O2 Reagent (MCO-H2O2-PV) Panasonic H2O2 solution is specially formulated for optimal use with the MCO-HP atomizer.

Each pre-measured bottle is sufficient for a complete H2O2 decontamination sequence.

Unit of issue: six per carton.

H2O2 Vapor Atomizer (MCO-HP-PW) Shown with connecting cable, standard.

No claim is made to the exclusive right to use ‘Cell” apart from mark as shown.

Ambient Temperature +24ºC

Integrated Cooling Coil (MCO-CL) Factory installed; specify when ordering.

Water bath/circulator not included. Permits stable operation at ambient or below ambient temperatures.

Extends performance specifications as follows: • Temperature Range: +18°C to +50°C, distribution ±0.25°C, variation ±0.1°C. • Relative Humidity: +5ºC above ambient to +50ºC, 95% ± 5%RH; 20ºC to 25ºC > 80%RH; 18ºC > 70%RH Includes temperature mapping results for individual unit per serial number.

82

Panasonic Healthcare Corporation of North America | Cell Culture Solutions

CytoGROW Optimal Series

Ideal for research and clinical microbiology, the Panasonic CytoGROW Optimal Series CO2 incubators offer a high performance solution for mainstream cell culture applications, where precise control and contamination resistance is critical.

Models: MCO-18ACL-PA, MCO-18ACUVL-PA, MCO-20AIC-PA Capacity: 6.0 & 7.6 cu.ft.

IR

MCO – 20AIC-PA

CO2 Incubators

Applications Clinical microbiology

MCO-18ACL-PA MCO-18ACUVL-PA

SYSTEM CONTAMINATION RESISTANCE IN SITU

CO2 Incubators

General research Growth studies

FEATURE

COMPETITORS

PANASONIC BENEFIT

Active Background Contamination Control with inCu-saFe® copperenriched stainless nsteel interior

Stainless steel

InCu-saFe® forms integral germicidal barrier against airborne contaminants; stainless steel does not offer a similar latent protection.

SafeCell UV protection located safely below the interior base destroys airborne contaminants as they pass over the humidity reservoir surface.

AIR AND WATER DECONTAMINATION IN SITU

SafeCell UV Protection (Optional)

Not available

CABINET CONSTRUCTION

Ease-of-use Direct Heat and Air Jacket design

Composite direct heat or water jacket

Panasonic design is sensitive to ambient temperatures, which permits the microprocessor-controlled, multi-zone Panasonic Direct Heat and Air Jacket system to work most efficiently. Panasonic maintains maximum temperature control and uniformity from three independent heating zones on all sides.

IR2 Sensor (MCO- 20AIC-PA Only)

TC Sensors

Panasonic proprietary single beam, infrared (IR2) CO2 sensors delivers precise CO2 control, quick recovery following door openings and auto sampling with no moving parts

CO 2 CONTROL

The Panasonic combination of InCu-saFe® and SafeCell UV minimizes downtime for total cleaning when required, with the benefit of continuous, preventive contamination control during normal operation.

Flexible Installation Options: With left-or right-swing outer door, CytoGROW Optimal Series offers the industry’s most flexible installation options available in either single or dual (stacked) cabinet configurations.

Convenient space efficient inventory management is simplified through a system of adjustable, extendable shelves.

Inventory shelves and brackets are formed from copper-enriched germicidal stainless steel, removable without tools.

Shelves are perforated to permit natural vertical air convection through and around labware.

Uniform Environment:

+ Temperature Uniformity

IR

+

CO2 /O2 Recovery

The patented Direct Heat and Air Jacket System eliminates the need for a conventional water jacket system, while achieving temperature stability, uniformity and fast recovery following door openings.

The automatic CO2 control system delivers precise, reliable and repeatable CO2 control MCO-20AIC-PA has an IR sensor, where as MCO-18ACL-PA has Panasonic designed TC sensors.

= Consistent Humidity Humidification is achieved by combined forced-air and natural evaporation method enhanced by the Direct Heat and Air Jacket system – Optical water level indicator warns when the water level reduces in the humidity pan.

Active Background Contamination Control:

+ InCu-saFe Interior ®

InCu-saFe forms an integral germicidal barrier against airborne contaminants and helps eliminate mold, spores and other contaminating spills while providing a noncorrosive environment. ®

+

=

Patented SafeCell UV Protection (optional)

Active Background Contamination Control

Located safely below the interior base destroys airborne contaminants as they pass over the humidity reservoir surface. Pathogens introduced during door openings are ultimately removed.

InCu-saFe® and SafeCell UV eliminates the need for time consuming, disruptive heat decontamination.

Panasonic minimizes downtime for total cleaning when required, with the benefit of continuous, preventive contamination control during normal operation.

(Available only with SafeCell UV option)

84

STABLE AND CONSISTENT ENVIRONMENT IN THE INCUBATOR

Panasonic Healthcare Corporation of North America | Cell Culture Solutions

MCO-18ACL-PA / MCO-18ACUVL-PA & MCO-20AIC-PA Specifications MODEL

MCO-20AIC-PA

MCO-18ACL-PA / MCO-18ACUVL-PA

DIMENSIONS INTERIOR ( W X F-B X H)

EXTERIOR ( W X F-B X H)

VOLUME

NET WEIGHT

24.4” x 20.6” x 26.2”

19.3” x 20.6” x 26.2”

620 x 523 x 665 mm

490 x 523 x 665 mm

30.3” x 27.9” x 35.4”

24.4” x 27.9” x 35.4”

770 x 709 x 899 mm

620 x 710 x 900 mm

7.6 cu.ft.

6 cu.ft.

215 L

170 L

205 lbs 93 kg

205 lbs 93 kg L LED digital display messaging

DISPLAY DATA ACQUISITION

Data Acquisition Automatic log function of temperature and CO 2 .

Data Acquisition Automatic log function of temperature and CO 2 .

COMMUNICATIONS

Catalog #MCO-420MA, remote alarm contacts standard. Optional 4-20mA connection. Optional PC interface, Catalog No. MTR-480 with RS232/RS485 data ports available.

Catalog #MCO-420MA, remote alarm contacts standard. Optional 4-20mA connection. Optional PC interface, Catalog No. MTR-480 with RS232/ RS485 data ports available.

SAFECELL UV SYSTEM

Standard

Optional

CO2 SENSOR

IR Sensor

Thermal Conductivity, Standard

INCU-SAFE® COPPER ENRICHED STAINLESS STEEL INTERIOR

Standard

Standard

Microprocessor Controller Standard

Microprocessor Controller Standard

Standard

Standard

INTERIOR UV LAMP, PROGRAMMABLE, OZONE FREE

Standard

Optional / 253.7 nm wave length, 4W / Standard

COPPER ENRICHED STAINLESS STEEL INTERIOR WITH GERMICIDAL PROTECTION

Standard

Standard, Copper-enriched stainless steel interior

ENERGY, ELECTRICAL & UTILITIES

N/A

N/A

MAXIMUM POWER CONSUMPTION

310W

310W

1062 BTU

1116 KJ/h

115V,60Hz with NEMA 5-15 plug provided; requires NEMA 5-15R grounded receptacle

115V,60Hz, 1 phase, NEMA 5-15P plug

4 to 6mm inner diameter tubing

0.25” barbed fitting

Nominal 4.3 PSI from two-stage CO2 regulator

5 psi from two-stage CO2 regulator

Optional, MCO-21GC, internal

Optional, MCO-21GC, internal

MAJOR OPERATING SYSTEMS

CONTROLLER/DISPLAY, DOOR MOUNTED DIRECT HEAT AND AIR (DHA) JACKET CONSTRUCTION

DECONTAMINATION

MAXIMUM HEAT DISCHARGE

ELECTRICAL CONNECTION

CO2 GAS CONNECTION CO2 GAS INPUT PRESSURE CO2 GAS CYLINDER SWITCH-OVER SYSTEM

85

Design Construction & Optional Accessories MODEL

MCO-18ACL-PA / MCO-18ACUVL-PA

MCO-20AIC-PA

CABINET DESIGN AND CONSTRUCTION SUPERSTRUCTURE, EXTERIOR CABINET AND DOOR

Galvanized steel exterior, baked-on enamel finish

Galvanized steel exterior, baked-on enamel finish

Copper-enriched stainless steel

Copper-enriched stainless steel

INNER DOOR

Tempered glass

Tempered glass

INSULATION

Rigid foam polyurethane

Rigid foam polyurethane

OUTER DOOR

Reversible, heated

Reversible, heated

Single opening with interior and exterior 30mm

Single opening with interior and exterior 30mm

non-VOC silicone stoppers

non-VOC silicone stoppers

4, adjustable

4, adjustable

Optional

Optional

P.I.D, setpoint resolution 0.1% and 0.1°C

Setpoint resolution 0.1% and 0.1°C

LED digital display messaging

LED digital display messaging

INTERIOR AND SHELVES

ACCESS PORT

LEVELING FEET

CONTROL, MONITORING, ALARM TEMPERATURE AND CO2 CONTROL DISPLAY

COMMUNICATIONS

Catalog #MCO-420MA, remote alarm contacts standard.

Optional 4-20mA connection.

Optional PC interface, Catalog No. MTR-480 with RS232/

LABALERT

Optional 4-20mA connection, MCO-420MA; optional PC interface, MTR-480, LabAlertTM Monitoring System

Optional

Optional

MCO-18UVS3-PA

MCO-18UVS3-PA

MCO-21GC-PW

MCO-21GC-PW

MCO-100L

MCO-100L

ROLLER BASE. FOR USE IN SINGLE OR STACKED INSTALLATIONS.

MCO-18RB-PW

MCO-18RB-PW

INCU-SAFE® FULL SHELF AND BRACKETS. INCLUDES TWO SHELF BRACKETS.

MCO-47ST-PW

MCO-47ST-PW

INCU-SAFE® HALF TRAY

MCO-25ST-PW

MCO-25ST-PW

MCO-CL

MCO-CL

MCO-420MA-PW

MCO-420MA-PW

OPTIONAL ACCESSORIES SAFECELL UV SYSTEM KIT* NARROW-BANDWIDTH 253.7NM LAMP AND ASSEMBLY. INCLUDES WATER LEVEL SENSOR AND WATER PAN COVER. AUTOMATIC CO2 CYLINDER SWITCHOVER SYSTEM* (PER CHAMBER) CO2 CYLINDER REGULATOR, CGA FITTING 320

INTEGRATED COOLING OPTION COMMUNICATIONS PORT. LOCATED AT REAR OF CHAMBER. CONNECTOR, CABLE AND SOFTWARE NOT SUPPLIED.*

Factory installed; specify when ordering. Specification subject to change without notice.

86

Panasonic Healthcare Corporation of North America | Cell Culture Solutions

CytoGROW

Compact Series Panasonic CytoGROW Compact Series CO2 and Multigas incubators offer precise CO2 and O2 control in a compact, space saving design, allowing up to 3 models to be stacked. These are ideal for in vitro simulation of the in vivo conditions in a laboratory environment.

Models: MCO-5ACL-PA, MCO-5M-PA Capacity: 1.7 cu.ft.

Applications

P.I.D Control Sophistication Proportional, integral and derivative infrared CO2 control accelerates recovery and prevents overshoot.

Small size makes it ideal for triple stacking in applications in IVF and ART procedures.

Stable and Consistent Environment in the Incubator:

+

+

InCu-saFe速 Interior

Zirconia O2 Control

Superior contamination control with an anti-bacterial copper alloy stainless steel interior offers germicidal protection, while providing a non-corrosive environment.

For Multigas CytoGROW Compact incubator, a solid zirconia oxygen sensor maintains sub-ambient O2 levels with high degree of precision. It has a long service life and has fast response to door openings.

+ Consistent Humidity The patented Direct Heat and Air Jacket System eliminates the need for a conventional water jacket system, while achieving temperature stability, uniformity, and fast recovery following door openings.

SafeCell UV Patented SafeCell UV technology uses a programmable ultraviolet lamp that sterilizes air and humidity water pan without affecting the cell cultures (optional).

• Digital Temperature Display • Heat ON Lamp • Visual alarm indicator

•Positive feedback tactile entry and function keys

High Performance with optimal conditions for in vitro modeling Stable temperature, humidity, and CO2 density are achieved through a combina­tion of performance systems supervised by a centralized microprocessor controller complete with alarm, programming, cali­bration, and diagnostic protocols export­able to remote database.

Technical Specification: MCO-5ACL-PA

UV DOOR RH PAN OVER HEAT

HEAT

INJECT

INJECT

MODEL NUMBER

49L 1.7 cu.ft.

MCO-5M-PA

108lb 49kg

88

HEAT

INJECT

49L 1.7 cu.ft.

INJECT

108lb 49kg

EXTERIOR

INTERIOR

EXTERIOR

INTERIOR

18.9”x 21.6” x 22.4” 480 x 548 x 575mm

18.9”x 14.9” x .14.8” 350 x 378 x 375mm

18.9”x 21.6” x 22.6” 480 x 548 x 575mm

18.9”x 14.9” x .14.8” 350 x 378 x 375mm

VOLUME (CU.FT.)

EXTERIOR DIMENSIONS (W X F-B X H)

CONTAMINATION CONTROL

CO2 CONTROL

1.7 49 L

18.9" x 21.6" x 22.4" 480 x 548 x 568 mm

inCu-saFe® copper-enriched stainless steel interior, Optional SafeCell UV with ultraviolet light,

Thermal conductivity

MCO-5ACL-PA MCO-5M-PA

UV DOOR RH PAN OVER HEAT

O2 CONTROL

VOLTAGE, POWER CONNECTION

---------Zirconia sensor with P.I.D/R recovery

115V NEMA 5-15

Panasonic Healthcare Corporation of North America | Cell Culture Solutions

CytoGROW ReachIn Series The MCO-80IC-PA is ideal for culturing large volumes of biological samples, performing short-term studies, and working with large volume cell culture apparatus. It includes Panasonicâ&#x20AC;&#x2122;s exclusive incubator technologies such as inCu-saFeÂŽ interiors, UV decontamination option, infrared (IR) CO2 sensor with P.I.D control, and features exceptionally low CO2 gas consumption.

Models: MCO-80IC-PA Capacity: 30.1 cu.ft.

IR

Applications Microbiological studies Plant Studies

Usability 30.1 cu.ft. Large capacity cabinet allows flexibility in usage. Cabinet will also accommodate a roller bottle apparatus, 5 bottles wide x 7 bottles high (requires mounting ramp kit).

Superior CO2 and Temperature Control: IR CO2 sensor with P.I.D microprocessor control and forced air circulation system delivers fast CO2 recovery characteristics. Exceptionally low CO2 gas consumption rates, less than half of similar competitive units.

P.I.D temperature control with deviation of ±0.1°C

Temperature Recovery

CO2 Recovery after 60 second door opening for the Panasonic MCO-80IC-PA

CO2 Recovery after 60 second door opening for Competitor

5%

5%

4%

4%

35°C

3%

3%

34°C

2%

2%

33°C

1%

1%

37°C 36°C

Door Close

10min

20min

Door Close

10min

10min

20min

Alarm, Buzzer Silence

Water Reservoir Level Indicator Open Door Indicator UV Decontamination ­– Light Indicator

Secondary Over Temp. Indicator

90

CO2 Display

Scroll Programming Buttons

Setpoint – Set Temperature and CO2

20min

Panasonic Healthcare Corporation of North America | Cell Culture Solutions

Horizontal Laminar Airflow System Panasonic’s CytoGROW ReachIn incubator’s cross shelf directed air flow system promotes optimum temperature uniformity throughout the chamber and contributes to quick temperature recovery after door openings. Utilization of Panasonic’s exclusive inCu-saFe® chamber material in the perforated side plenum, minimizes contamination concerns and direct positive and negative pressure air flow.

Humidified air minimizes potential for cell culture media desiccation.

Perforated sidewall panels right (pressure) and left (negative pressure) assure a positive, gentle airflow from right to left.

Access ports (each side, 40mm).

Optional Shaker shelves with additional support available in 2 or 3 shelf configurations.

Horizontal airflow maintains accurate temperature and CO2 control and uniformity at all shelf levels, top-to-bottom, front-to-back.

Optional SafeCell UV decontamination system provides decontamination of the humidity reservoir.

SafeCell UV protection with Humidity Selection: (optional feature) Panasonic’s patented SafeCell UV decontamination system decontaminates the humidifying water reservoir and helps in eliminating the contamination concerns due to regular door openings.

Humidity reservoir heaters are located on the outside walls of the reservoir and are not as susceptible to corrosion and scaling from water as competitive systems are. The unit can be set to both nominal (above 80% RH) and high humidity setpoints (above 90% RH).

+ InCu-saFe® Interior InCu-saFe forms an integral germicidal barrier against airborne contaminants and helps eliminate mold, spores, and other contaminating spills, while providing a noncorrosive environment. ®

= Patented SafeCell UV Protection (optional) Located safely below the interior base, it destroys airborne contaminants as they pass over the humidity reservoir surface. Pathogens introduced during door openings are ultimately removed.

OPTIMUM PROTECTION FOR LARGE CAPACITY INCUBATOR 91

Accessories & Technical Specification: OPTIONAL ACCESSORIES Built in gas automatic switcher kit

MCO-80GC-PW

Roller bottle apparatus mounting ramp kit

MCO-80RBS-PW

Inner Door Kit 5 partition doors, made with acrylic resin

MCO-80ID-PW MCO-80UVS-PA

UV sterilization of humidifying water reservoir only

MCO-80AS-PW

Automatic water supply system: Includes control box, water tank, water supply hose, 18L (4.8 gallon) tank Additional shelf

MCO-80ST-PW

4 to 20 mA analog output module

MCO-420MA-PW

CO2 tank regulator

MCO-100L

Reinforced shelves for shaker use

MCO-80IC3RSLF

Optional

LABALERT TM

DIMENSIONS OVERALL EXTERIOR DIMENSIONS (W X F-B X H)

33.8” × 33.6” × 80.3” / 986 × 853 × 2040 mm

INTERIOR DIMENSIONS (W X F-B X H)

31.7” × 27.3" × 60.0” / 806 × 693 × 1524 mm

INTERIOR VOLUME SHELVING (W X F-B X H)

30.1 cu.ft / 851 L 30.5” x 25.9” x 0.4” / 776 x 659 x 10 mm Load Capacity: 66 lbs. / 30 kg

CONSTRUCTION EXTERIOR CABINET

Electrogalvanized Steel (Acrylic resin baking painted finish)

INTERIOR CABINET

Copper Alloy Stainless Steel (expect humidifying reservoir)

EXTERNAL DOOR SHELVING NET UNIT WEIGHT ACCESS PORTS

Double Paned Glass Door with out door latch Copper alloy Stainless Steel (5 standard) 605 lbs. / 275 kg.

40 mm(1.57”), 2 locations (right and left sides) with silicone rubber stopper)

ENVIRONMENTAL PERFORMANCE TEMPERATURE CONTROL RANGE

+5°C above ambient to 50°C (in a 20°C to 35°C ambient)

TEMPERATURE UNIFORMITY DEVIATION

±0.5°C (in 25°C ambient, setting 37°C, 5% CO 2 , no load 9 point measurement)

TEMPERATURE FLUCTUATION MARGIN

±0.1% (in 25°C ambient, setting 37°C, 5% CO 2 , no load)

CO 2 CONTROL RANGE

0 to 20% ±0.15%, no load

CHAMBER HUMIDITY

Over 80% RH (High humidity mode: over 90% RH)

ENVIRONMENTAL CONTROLS HUMIDIFYING RESERVOIR

Integrated with an inner chamber (Stainless Steel, SUS304)

HUMIDIFYING METHOD

Heated vaporization with water in humidity pan (High humidity mode available)

HIGH HUMIDITY MODE

Selectable by function mode (for over 90%RH)

HUMIDIFYING WATER RETENTION DAYS (REFERENCE) HEATING METHOD TEMPERATURE CONTROL SYSTEM TEMPERATURE DISPLAY WATER DRAINAGE WATER FILL CO 2 GAS CONTROL CO 2 GAS INLET PRESSURE

15 days (Reference) (Under a condition of 25°C ambient, setting 37°C, 5% CO 2 , no load, no door opening, 80%RH) Heater with fan air circulation, cross shelf laminar air flow Microprocessor P.I.D with thermistor sensor, temperature fluctuation of +0.1°C Digital display (0.1°C increments) Drainage valve (lower side of front frame) Drainage into a tray/bottle (provided) Water fill located at the front side of interior bottom (optional auto-fill) Microprocessor P.I.D with infrared sensor (0.1% increments) 15 psi (0.1 MPa)

ELECTRICAL POWER REQUIREMENTS INTERIOR/EXTERIOR CONVENIENCE RECEPTACLE ALARMS REMOTE ALARM CONTACTS

92

115V, 20 Amps, 60 Hz, NEMA 5-20P Plug Interior Duplex: Vapor Proof. 115V, 3 Amps Max. Rating - Exterior Duplex:115V, 1 Amp. Max Rating High/Low Temperature Alarm. CO2 density alarm.

Upper limit temperature Alarm. Door Ajar Alarm, Self Diagnostics N.O. (normally open) and N.C. (normally closed) contacts included, rating DC 30v, 2A

Panasonic Healthcare Corporation of North America | Cell Culture Solutions

Heated and Refrigerated Incubators

Panasonic MIR series incubators are designed for general laboratory applications requiring fixed setpoint or cycling temperature control. A selection of five cabinet sizes offers programmed operation and integrated alarms for a wide temperature range.

Models: MIR-154-PA, MIR-254-PA, MIR-554-PA

MIR-162-PA, MIR-262-PA

Heated and Refrigerated Incubators VOLUME (CU.FT.)

EXTERIOR DIMENSIONS (W X F-B X H)

HEATED

REFRIGERATED

PROGRAMMABLE TEMPERATURE

MIR-162-PA

3.3 93 L

22.8" x 23.4" x 32.3" 580 x 595 x 820 mm

Yes

—

5ºC above ambient to 80ºC

MIR-262-PA

5.4 153 L

28.7" x 25.4" x 34.3" 730 x 645 x 870 mm

Yes

—

5ºC above ambient to 80ºC

MIR-154-PA

4.3 123 L

27.6" x 22.8" x 40.1" 700 x 580 x 1018 mm

Yes

Yes

- 10ºC to 60ºC

MIR-254-PA

8.4 238 L

27.6" x 22.8" x 63.7" 700 x 580 x 1618 mm

Yes

Yes

- 10ºC to 60ºC

MIR-554-PA

14.3 406 L

31.5" x 32.8" x 71.3" 800 x 832 x 1810 mm

Yes

Yes

- 10ºC to 60ºC

MODEL NUMBER

VOLTAGE, POWER CONNECTION

115V NEMA 5-15

Programmable for multifunction laboratory applications.

Refrigerated Incubators, Environmental Testing Chambers The Panasonic MIR series offers accurate control and uniformity in a wide range of temperatures, making them suitable for various testing applications.

Programmable with 12 step, 10 program capability and wide temperature range that goes from -10°C up to +60°C with excellent temperature uniformity.

Improved usability with modern design, improved gentle air circulation that reduces media drying, and adjustable low vibration.

Wide Range of Applications The MIR-154-PA and MIR-254-PA refrigerated incubators are ideal for testing applications such as: Industrial testing in the electrical, machinery, textiles industries Chemical testing e.g., storage, stability, acid/alkali, durability Food industry for packaging, quality control, and stability Testing for waste water, BOD, soil testing Microorganism culturing Germination experiments

Programmable Numeric direct keyed input MIR-554-PA

Memory of operation start date and hour with delay start timer Either clock mode or count down mode can be used for program setting MIR-262-PA

94

Panasonic Healthcare Corporation of North America | Cell Culture Solutions

Flexibility

LCD Controller

The Panasonic MIR series offers accurate control and uniformity in a wide range of temperatures, making them suitable for various testing applications.

The LCD Controller improves user interface for better programming and control. The controller features a pop up menu that can display:

• The MIR-154-PA and MPR-254-PA are programmable with 12 step, 10 program capability • Wide temperature range from -10°C to +80°C • Excellent temperature uniformity • ON-OFF control of chamber lighting – controlled by programming

• Current conditions (temperature, date, time (12 hour or 24 hour selectable) • Alarm condition • Door Openings • Light status

Improved Usability

• Various settings of each program (12 step, 10 program, clock function and join mode)

• Gentle air circulation that reduces media drying • Adjustable low vibration for sensitive materials testing • Full alarm package

• Optional wireless monitoring via LabAlert

Energy Savings A microprocessor-controlled high efficient heater output and compressor ON/OFF allow for energy efficient operation. In addition, a renewal control program and low heat-emission inner chamber fan are newly adopted that help in high-energy saving operation over a wider range of ambient environments.

Energy Savings: In addition to a microprocessor-controlled high efficient heater output and compressor ON/OFF, a renewal control program and low-heat emission inner chamber fan are newly adopted to allow high-energy saving operation over a wider range of ambient environments.

P.I.D. Controller Microprocessor-based P.I.D. (proportional, integral, derivative) control with digital input, full-function alarm, and monitoring.

• Controls for High & Low Temp. Alarm

• Direct entry keypad

• Menu call button

• Program step buttons • Lighting override button

• Graphic alpha numeric display

• Buzzer silence • Control for LCD Contrast

95

Heated and Refrigerated Incubator Specifications MODEL NUMBER

MIR-154-PA

MIR-254-PA

MIR-554-PA

4.3 cu.ft.

123 L

8.4 cu.ft.

238 L

14.3 cu.ft.

406 L

EXTERIOR DIMENSIONS W X F-B X H

27.6” x 22.8” x 40.1” 700 x 580 x 1018 mm

27.6” x 22.8” x 63.7” 700 x 580 x 1618 mm

31.5” x 32.8” x 71.3” 800 x 832 x 1810 mm

INTERIOR DIMENSIONS W X F-B X H

24.4” x 15.2” x 21.9” 620 x 386 x 555 mm

24.4” x 15.2” x 42.8” 620 x 386 x 1088 mm

25.2” x 21.7” x 45.7” 640 x 550 x 1160 mm

EFFECTIVE CAPACITY

EXTERIOR FINISH

Galvanized Steel with baked on finish

INTERIOR FINISH

Stainless Steel

DOOR SHELVES

Reversible painted steel & triple pane glass with observation window

Reversible painted steel & triple pane glass with observation window

Painted steel & triple pane glass with observation door & key

3, PE coated steel wire, adjustable

5, PE coated steel wire, adjustable

5, PE coated steel wire, adjustable

INSULATION

Foam-in-place rigid polyurethane

CIRCULATION SYSTEM COMPRESSOR

Forced air circulation 150W, Hermetic Type

250W, Hermetic Type

EVAPORATOR

Fin and tube type, forced air circulation

CONDENSER

Wire and tube type natural air cooling system

DEFROSTING SYSTEM HEATER

Selectable manual start or timer defrost, natural vaporisation of drain water 141W, Cord Heater

218W, Cord Heater

TEMPERATURE SETTING INDICATION

332W, Cord Heater

Digital Setting with Digital Display

TEMPERATURE CONTROL

Microprocessor P.I.D system, (when compressor operates, ON/OFF control)

TEMPERATURE SENSOR

Thermistor

AUTOMATION SETTING TEMPERATURE ALARM

When temperature deviates approx. ±2.5°C, visual and audible alarm

OVER TEMPERATURE PROTECTION DEVICE

Visual audible alarm

PROGRAMED OPERATION

12-step repeat from 1-98 times or continuous repeat

TEMPERATURE RANGE TEMPERATURE CONTROLLABILITY

-10°C to 60°C ±0.2°C at heater P.I.D control (Temperature setting 50°C, ambient temperature 20°C, no load) ±1-5°C at compressor ON/OFF control (Temperature setting 5°C, ambient temperature 20°C, no load)

TEMPERATURE UNIFORMITY

±0.5°C (Temperature setting 37°C, ambient temperature 20°C, no load)

POWER SOURCE: VOLTAGE POWER CONSUMPTION

115V / 60Hz / 1 phase 160 W

INTERIOR LAMP NET WEIGHT ACCESSORIES

96

250W, Hermetic Type

240 W

290 W

15 W x 1, fluorescent lamp (setting temperature +5°C to 50°C) 172 lbs 78 kg

238 lbs 108 kg

453 lbs 205 kg

Key 1 set, Light shielding plate 1

Key 1 set, Light shielding plate 1

Key 1 set

Panasonic Healthcare Corporation of North America | Cell Culture Solutions

Plant Growth Chamber

The model MLR series humidified plant growth chamber has a temperature range of 0째C to 50째C, with programmable lighting and humidity control for diurnal protocols in plant and insect experiments.

Models: MLR-352H-PA

Versatile Environmental Test Chamber Graphic LCD provides easier operation Programmable temperature, lighting and humidity function Microprocessor P.I.D. temperature control Data logging function Easy calibration through controller Small lightweight, high molecular membrane-type humidity sensor

Technology

Programmable

The wide variety of temperatures, humidity, and lighting patterns that are essential in research and environmental studies, can now be accurately reproduced and controlled.

Nine user programmable steps allow simulation of environmental conditions. 15 variable intensity fluorescent lamps create uniform lighting.

Microprocessor P.I.D. Control

Gentle Air Circulation

Allows accurate, reproducible, and flexible programming of all performance parameters with optimal energy management.

Comprehensive security monitoring and alarm functions are standard. The temperature and humidity inside the incubator can be set and monitored easily by means of precise microprocessor temperature control with an LCD graphic display. The temperature fluctuations allow precise experiments plus energy.

Maximizes temperature uniformity at all shelf levels.

Ergonomic Design Slim-profile cabinet offers sophisticated performance in minimal space.

Alpha-Numeric Controller The LCD controller improves user interface for easy programming and control.

Dimensions MODEL NUMBER MLR-352H-PA

VOLUME (CU.FT. PER CHAMBER)

EXTERIOR DIMENSIONS (W X F-B X H)

INTERIOR DIMENSIONS (W X F-B X H)

10.4 cu.ft 294 L

29.9” x 27.6” x 72.2” 760 x 700 x 1835 mm

20.5” x 19.3” x 44.7” 520 x 490 x 1135 mm

Environmental Controls

Plant Growth Chamber

ENVIRONMENTAL PERFORMANCE

ENVIRONMENTAL PERFORMANCE

TEMPERATURE PROGRAMMABLE OPERATION

12 steps (10 patterns), 98 cycle or limitless; Clock mode: 00:00 to 23:59, Timer mode 00:01 to 99:59)

TEMPERATURE CONTROL

P.I.D. microprocessor control and refrigeration capacity control

REFRIGERANT

R404A

HEATER

340W

HUMIDITY CONTROL SYSTEM DEFROSTING SYSTEM

Automatic defrost (3 patterns), manual defrost Fin and tube type, forced circulation

AIR CIRCULATION

Fin and tube type, forced circulation Fully hermetic, 325W output

Temperature Distribution (°C) Point

98

TEMPERATURE DISTRIBUTION

±1.0°C (lamp OFF) ±2.5°C (lamp ON)

CONTROLLABLE HUMIDITY RANGE

Ultrasonic P.I.D. Control

The temperature distribution (°C) is determined using ½H and center point (5) as the zero reference.

5°C to 50°C (lamp OFF) 10°C to 50°C (lamp ON)

TEMPERATURE ACCURACY

EVAPORATOR

COMPRESSOR

TEMPERATURE RANGE

1

0

2

+0.2

3

+0.1

4

+0.1

5

0

6

+0.3

7

+0.4

8

+0.2

9

+0.3

±0.3°C 55-86% & 60-90% RH

Panasonic Healthcare Corporation of North America | Cell Culture Solutions

CPWS

Cell Processing Work Station Models: MHE-PF4025C-PA | MHE-UN4025CW-PA

The Essential Work Station for Cell Therapeutics In designing the industryâ&#x20AC;&#x2122;s first viable alternative to a conventional Class 10,000 cleanroom for both Class 100 air quality and barrier isolation, Panasonic has introduced the Cell Processing Work Station (CPWS). It brings the potential of cell therapeutics to more facilities, while decreasing acquisition costs, operation costs and protracted time lines.

Minimizes Cleanroom Expense Self-Contained Space-Saving Easy to Install MP Compliant for Aseptic Process G User Friendly Energy Efficient, Green Design

Technical Attributes The Panasonic CPWS is a component-based design that permits a long-term or quick turnover of self-contained protocols with efficiency and safety. As an integrated system, all functions associated with good laboratory technique, environmental control, and ergonomic comfort are selected for compatibility and complementary functional performance.

The Panasonic CPWS work station is designed to deliver efficient, cost effective, GMP compliant cell therapy, and manufacturing capability without the expense and inconvenience of a class 10,000 cleanroom. The CPWS offers significant advantages over conventional hard wall cleanroom construction.

The CPWS is less expensive than a cleanroom.

It is quicker to acquire and place into operation.

The small footprint increases options for location and orientation.

Fast decontamination and change-over improve productivity, increase throughput and deliver quicker return on investment.

The user-friendly glove box design eliminates gowning and improves operator comfort and convenience.

Recordkeeping and process documentation are easier to manage.

Operating costs are lower than cleanroom costs

Optional centrifuge integrated into the work surface

Central barrier isolator

Optional CO2 incubator with docking collar

Pass box interchange Integrated H2O2 decontamination system Optional cell observation system with microscope and monitor The optional incubator and optional centrifuge operate within a Class 100 environment.

100

Work is easily suspended and resumed without the need to de-gown and re-gown, improving user comfort.

Components and operating systems are configured around a central work station with a HEPA filtration and air management system designed to deliver Class 100 air to the work surface within the glove box.

Panasonic Healthcare Corporation of North America | Cell Culture Solutions

3

1 7

11

4

13

2

5

8

6

9

12

10

1 Hinged front access assembly; front lifts up when total interior access is required.

2

3

Interchange pass box with manually initiated, automatic sequence H2O2, decontamination system

HEPA supply and exhaust filtration blower motor assembly

4

Interior fluorescent lamps

10

Adjustable leveling feet

5

Glove port

11

Optional cell monitor LCD

6

Electrical compartment

12

7

System controller

8

Centrifuge module accessible for the aseptic work area.

9

Centrifuge controller

13

Incubator cart with locking casters; offset casters nest with frame assembly when docked.

Modular CO2 incubator, shown on cart, docked to barrier isolator.

101

Feature Benefit Analysis Aseptic Environment Required for Cell Preparation Usually, human derived cells must be guaranteed that they are prepared and cultured in an aseptic environment because they cannot be treated by heat or pressure.

Orginal Cells

Preparation

Extraction

Culture

CPWS SOLUTION

TYPICAL CLEANROOM

Glove Box

HEPA Filters

Class 10,000

Class 100,000

Pass Box

* Drawing not to scale

CLEANROOM WITH BIOLOGICAL SAFETY CABINETS

Closed system, requires only Class 100,000 air

Open system, requires significant investment and maintenance of background environment, Class 10,000 air

Minimal; Cost of Class 100,000 room plus CPWS

High; Cost of Class 10,000 cleanroom plus Class 100 one or more Class 100 biological safety cabinets

Minimal footprint in existing space

Dedicated new/retrofit facility with significant requirement for HVAC, filtration, air showers

GENERAL

SPACE/FOOTPRINT ALLOWANCE VALIDATION COSTS

Minimal; Requires Class 100,000 only.

High; Requires both Class 100 and Class 100,000.

OPERATION COST

Low

High; Repeated decontamination and maintenance costs. Higher consumables cost

IMPLEMENTATION

Weeks

Months or Years

No second gowning required. Central barrier isolator with ergonomically angled front permits easy access through glove ports. Reduces stress on workforce.

Conventional first and second gowning, external air supply, interlock doors/air showers

FLEXIBILITY

Elimination of hazardous fumes for decontamination permits diverse applications. Elimination of depolymerizing formaldehyde, formalin and other toxic chemicals permits transition between applications seamlessly.

Inflexible

THROUGHPUT

Expanded. Quick changeover extends use, optimizes return on investment. Component integration streamlines workflow while enhancing aseptic processing.

Limited due to product changeover criteria

ERGONOMICS AND USER COMFORT

DECONTAMINATION EQUIPMENT AND INSTRUMENTATION

102

Class 10,0 00

Class 100,000

More Cost

PANASONIC CPWS BARRIER ISOLATOR

COMPARISON

ISO14644-1

Class 100-BSC Class 10,000

Class 100,000

Efficient

Detachable Incubator

PLANNING AND LEAD TIME

Change Room

35%

Class 100

Centrifuge

Prepared Cells

Administration

Two Hours

Up to Two Weeks

Microscopes and other instrumentation can be dedicated to the work station.

Shared instrumentation in an open system exposes processes to cross contamination.

FDA

EU-GMP ANNEX 1

JP

WHO-GMP TRS902 ANNEX 6

CLASS 5

Class 100 In Operation 3,520

Grade A In Operation 3,500

Grade A In Operation 3,520

Grade A In Operation 3,500

CLASS 7

Class 10,000 In Operation 35,200

Grade B In Operation 350,000 At rest 3,500

Grade B In Operation 352,000 At rest 3,520

Grade B In Operation 350,000 At rest 3,500

CLASS 8

Class 100,000 In Operation 3,520,000

Grade C In Operation 3,500,000 At rest 350,000

Grade C In Operation 3,520,000 At rest 352,000

Grade C In Operation 3,500,000 At rest 350,000

CLASS 9

â&#x20AC;&#x201D;

Grade D At rest 3,500,000

Grade D At rest 3,520,000

Grade D At rest 3,500,000

Panasonic Healthcare Corporation of North America | Cell Culture Solutions

Cost Benefit Analysis Approximately 35% Less Expensive to Operate The Panasonic CPWS offers significantly lower operating costs when compared to a conventional cleanroom (open system). Comparison methodology and assumptions are available from Panasonic. Soft-cost benefits related to user convenience, user comfort, flexibility, throughput, and other demonstrated advantages of the CPWS can be established through consultative review. Contact Panasonic for details.

Comparative Operating Costs1 (Nominal), Panasonic CPWS vs. Conventional Cleanroom, Annual PANASONIC CELL PROCESSING WORK STATION (CPWS)

FUNCTION

CONVENTIONAL GMP CLEANROOM

ANNUAL BUDGET (NOMINAL)

FUNCTION

ANNUAL BUDGET (NOMINAL)

H2 O 2 Cartridge, 25g, Total System Decontamination

$9,000

Disinfection, Cleaning

$9,000

H2 O 2 Cartridge, 5g, Pass Box Only Decontamination

$13,320

Routine Sanitation

$12,000

Residual H2 O 2 Detector

$2,664

Particle Sensors

$3,000

Gloves, 3 gloves, 2×

$1,140

Sterilized, Non-Shedding Gowns

$18,000

Sleeves, 3 gloves, 1×

$3,640

HEPA FILTERS

HEPA FILTERS

Biosafety Cabinet, Supply Filter

$343

$907

Biosafety Cabinet, Exhaust Filter

$190

Interchange Pass Box

$294

Certifier Labor, BSC Formalin Decontamination

Room

$833

Cleanroom Air Supply

Labor

$1,330

Work Station

VALIDATION EXPENSES

$956 $2,916

Cleanroom Air Exhaust

$1,516

Certifier Labor, CR Formalin Decontamination

$1,500

$1,440

VALIDATION EXPENSES

Decontamination Performance BI Inspection

$3,230

Biosafety Cabinet and Report

$1,050

Cleanroom and Report

$10,000

Centrifuge and Report

$1,350

H2 O 2 Mist Uniformity Inspection

$720

Centrifuge Module and Report

$1,350

CO 2 Incubator Module and Report

$1,250

POWER CONSUMPTION

$18,057

NOMINAL ANNUAL BUDGET

35% Less

Cleanliness and Air Volume Report

CO 2 Incubator Module and Report

$850

POWER CONSUMPTION

$60,000

NOMINAL ANNUAL BUDGET

$28,972

$91,600

Comparative operating costs listed herein are nominal and based on actual installations in Japan. Total cost of ownership and operation will vary according to type of installation, method of use, geographic location and other factors. Panasonic offers consultative assistance in developing a cost/ benefit analysis specific to your facility and protocol. Contact Panasonic to arrange a report unique to your prospective application

1

Who Benefits from CPWS MARKET

FACILITY

PROTOCOL

CPWS BENEFIT

ACADEMIC

Cancer centers

Cancer treatment, translational medicine

Easy segregation of patient-specific cells

ACADEMIC

Medical research

Regenerative medicine

CLINICAL

Hospitals

PRIVATE INDUSTRY

Biotechnology, Pharmaceutical

Easier transition from animal models to human clinical trials

103

Barrier Isolator DIMENSIONS OVERALL EXTERIOR DIMENSIONS (W X F-B X H) INTERIOR DIMENSIONS (W X F-B X H) INTERIOR WORK SURFACE ELEVATION GLOVE ELEVATION PASS BOX INTERCHANGE (W X F-B X H) NET WEIGHT

115" × 41" × 87.8" / 2920 × 1045 × 2230 mm net of attached optional incubator 70.7" × 28.5" × 34" / 1796 × 726 × 864 mm 31.5" above floor / 800 mm 41.3" above floor / 1050 mm 19.6" × 16.7" × 15.8" / 500 × 425 × 400 mm 2207 lbs / 1000 kg, nominal

CONTROLS, ALARMS PRESSURE MONITOR FAN MOTOR

Red LCD and audible alarm if pressure falls below alarm setpoint.

Audible alarm during motor shutdown

CONSTRUCTION EXTERIOR FINISH

Painted steel

INTERIOR FINISH

Polished stainless steel

FRONT GLOVE PORT PANEL, ANGLE 6°

Polycarbonate with painted steel frame. Hinged for opening to load equipment.

AIR SYSTEM AIR QUALITY AIRFLOW SYSTEM AND VELOCITY

Grade A Class 100 over work surface; installation in a Grade D, Class 100,000 ambient room Vertical downflow over work surface, 0.2~0.3 m/s ± 20% @6" below supply filter screen (150 mm)

FILTRATION SYSTEM

Independent HEPA supply and exhaust filters, efficiency 99.99% (0.3 µm PAO), scan tested and passed

FILTRATION SYSTEM, PASS BOX

Independent HEPA supply and exhaust filters, efficiency 99.99% (0.3 µm PAO), scan tested and passed

INTAKE AND EXHAUST

Electrically switched system. Room air intake through HEPA supply filter; return exhaust to room thru HEPA exhaust filter

RELATIVE AIR PRESSURE WORK STATION PASS BOX INTERCHANGE

Positive pressure after decontamination of work station and pass box; audible notification when ready, 60Pa Positive pressure after decontamination of pass box only; audible notification when ready, 220Pa

INTERIOR WORK AREA LIGHTING ELECTRICAL OUTLET

Fluorescent lamps (3), 30w each, top of panel, top of right, left Duplex, drip-proof receptacle

PASS BOX INTERCHANGE DOOR MATERIAL

Front opening to outside; left side opening to interior work area Polished stainless steel

DECONTAMINATION SYSTEM FUNCTION H2O2 RESOLUTION AND AERATION DECONTAMINATION CYCLE TIME

H2O2 vaporization; simultaneous decontamination of interior barrier isolator work station, pass box interchange, optional centrifuge and optional CO2 incubator Catalytic, external to the work area. Residual H2O2 density at catalytic outlet is at or below 1ppm (by TLV-TWA). Fresh, HEPA filtered air follows resolution Load dependent; typical cycle times range from 1.0 to 2.0 hours from manual initiation of automatic sequence.

UTILITIES ELECTRICAL

104

Main system, 4500w, 220V, AC, 60Hz. Electrical outlet 120V, AC, 60Hz.

Panasonic Healthcare Corporation of North America | Sterilization

Top-Loading

Portable Autoclaves

MLS-3751L-PA

Panasonic MLS series top-loading autoclaves are a popular method of sterilization for today’s research laboratories. Self-contained and easy to use, these reliable energy-saving autoclaves are ideal for a wide range of applications, including liquid culture media preparation, labware, and waste sterilization. Our equipment is designed to meet good laboratory practice criteria in biotechnology, pharmaceutical, and clinical laboratories. Panasonic MLS series portable autoclaves deliver high pressure steam with speed, efficiency, and reliability, for research lab usage only. The MLS autoclave series is designed for individual lab use and can be conveniently moved from one lab to another.

Models: MLS-3751L-PA, MLS-3781L-PA Programmable Allows maximum flexibility in ramp up, dwell, ramp down, and cool-off protocols.

Pre-Set Programs These units offer a total of 12 pre-set programs to choose from on a simple-tooperate control panel with lighten temperature/time indicators. They also allow for independent programming for users to set their own programs Sterilizing: For water, culture media, regents and other fluids.

After completion and cooling to a selected temperature. Air is expelled automatically through exhaust valves.

Sterilizing/Keep Warm: After sterilizing culture media, reagents and other liquids. High temperature prevents solidifying.

Melting/Keep Warm: To melt or keep culture media at a fixed temperature.

Instrument Sterilizing: For flasks, beakers, test tubes, and other lab instruments.

MLS-3781L-PA

Top-Loading Portable Autoclaves EFFECTIVE CAPACITY (CU.FT.)

EXTERIOR DIMENSIONS (W X F-B X H)

MAXIMUM TEMP.

BASKETS (INCLUDED)

FLASK CAPACITY (1L)

CROSS SECTION

VOLTAGE, POWER CONNECTION

MLS-3751L-PA

1.8 50 L

18.8" x 24.9" x 29.4" 478 x 632 x 748 mm

135°C

2

8

14.6" (37cm) 371 mm

115V NEMA L5-20

MLS-3781L-PA

2.6 75 L

18.8" x 24.9" x 38.0" 478 x 632 x 965 mm

135°C

3

12

14.6" (37cm) 371 mm

208/230V NEMA L6-30

MODEL NUMBER

Easy mobility for sterilization on demand.

105

1. Digital display I

4. Setting confirmation button

7. Object temperature button

Indicates the current temperature, sterilization set temperature, melting set temperature, exhaust starting temperature, date, hour/minutes, and voice guide setting.

Indicates change of settings and settings of current operation on the digital displays I and II.

When the optional object temperature sensor is installed and this object temperature button is pressed, the lamp lights up.

2. Selection indicator lamp Indicates the selected sterilization cycle with a lit lamp.

3. Cycle/program selector button Selects any of 3 programs and 4 cycles (total 12 selections).

5. Digital display II Indicates the set time, remaining time, sterilization cycle, exhaustrate, cautionary messages, error messages, date and voice guide setting.

6. Under-pressure lamp Lights up when the chamber is internally under pressure.

8. Process monitor lamp Indicates the status of the current process with a flickering bar.

9. Cooling fan button Used to engage the cooling modeduring exhausting.

1 8

2 5

7

6

3

9

4

Microprocessor Controls

Programmable

Assures correct temperature and is accurately maintained, easily operated with one-touch operation. Sterilizing temperature is controlled by the microprocessor within +2°C of the set temperature in the range of 115°C to 135°C.

Allows maximum flexibility in ramp up, dwell, ramp down and cool-off protocols.

Process Voice Notification

※ボタン表示変更 下記のみ変更

The MLS series includes a voice notification of the system process. Each step of the process is notified via a pre-recorded voice message, allowing the end user to hear the process as it is happening.

Compact Design, Large Chamber変更前

変更後

Maximizes use of available lab floor space, stores easily when not in use. 14.6 inch diameter wide chamber offers large capacity, storing example load of 8 (MLS-3751L-PA) or 12 (MLS-3781L-PA) 1,000 ml flasks.

Swing-Up Lid Opens chamber for 100% access; eliminates side space requirement.

Printer Optional built-in process printer for batch documentation available. The printer prints out the process run results of temperature, pressure, vs. time. Each printout is date and time stamped.

106

Pre-Set Programs These units offer a total of 12 pre-set programs to choose from on a simple-to-operate control panel with lighten temperature/ 2007.6.20付け 【変更箇所あり】 2007.6.20 time indicators. They also allow for independent programming for users to set there own programs ※裏面印刷

※表面ツヤ消し ツヤ消しは国 Sterilizing: For water, culture media, regents and other： fluids.

After completion and cooling to a selected temperature. ソウサヒョウジバン、3781EX Air is expelled automatically through exhaust valves.

機種名 ：ＭＬＳ−3751,3781 Sterilizing/Keep Warm: After sterilizing culture media, reagents and other liquids. High temperature prevents テガ三洋工業 デザイン・開 solidifying.

Melting/Keep Warm: To melt or keep culture media at a fixed temperature.

Instrument Sterilizing: For flasks, beakers, test tubes, and other lab instruments.

Panasonic Healthcare Corporation of North America | Monitoring

24/7

Monitoring Solutions

LabAlert

TM

Monitoring System For iPhone, iPad & Android devices

For Web

Access your LabAlertTM account from anywhere, at any time.

All you need is a computer, smartphone or tablet device.

The web and app-based interfaces let you set up customizable dashboards to centrally monitor your equipment in a single view.

SIMPLE SETUP STEP 1 - Unit • Install Sensor within the equipment chamber • Plug in Probe to Sensor

STEP 2 - Receiver • Open equipment Access Port • Place Probe into the equipment

STEP 3 - Cloud • Position Probe in Chamber • Activate Sensor

STEP 4 - You • Sensor Communicates with Gate • Customer Monitors Data on LabAlertTM

108

ADVANTAGE

LABALERTTM

COMPETITORS

Cost

Economical and versatile choice Cost decreases with the increase in units

Not economical with larger number of units

Compatibility

Compatibility with multiple systems

Not compatible to other units

Compliance

21 CFR Part 11 Compliance, NAFEM data protocol, TJC standard and HACCP

Most of them are 21 CFR Part 11 compliant

Hosting

Web, App, Cloud, Standalone Software

Only web or local

Range

WiFi - 2.4 GHz

Wired or Wireless

Scalability

Ability to expand infinitely for multiple units

Do not have such flexible capabilities

Maintenance

Preventative maintenance reminders and reports with service alerts

Simple summary of real time data + Historical chart data

FEATURE

Panasonic Healthcare Corporation of North America | Service, Technical Support & Validation

Professional Service and Support We provide full product service support to maintain Panasonic standards of product safety, reliability and high performance. The combination of our multi-national network of factory-trained service professionals, detailed documentation of field performance, and high-value on the customer feedback helps us to deliver best-in-class, end-user support for our customers.

Convenience of Panasonic Product Service • Panasonic service specialists are trained to: - Perform remote and on-site diagnostics - Repair and replace worn components - Offer preventative maintenance programs as per your needs and budget • Many Panasonic Healthcare products include self-diagnostics that permit authorized service technicians to determine how and when service calls are required.

• We offer training to selected facility biomedical engineers and service staff for authorized in warranty and post-warranty repairs.

• Because our products are sold and serviced worldwide, products acquired in one country under grant or facility-sharing programs are easily supported if moved to facilities in the next city or around the world.

109

Validation Services Panasonic offers a wide range of highquality services for all our equipment.

These services include on-site validation, customer validation support packages, factory acceptance testing and NIST calibration.

Choosing Panasonic as an equipment supplier and validation consultant can greatly reduce the time and cost involved with getting new equipment compliant and ready for use.

110

Unique Services Panasonic Offers: • On-site consultation • Unit specific authorized protocol documents • Customizable testing procedures to meet customer specific requirements • Free archiving of unexecuted testing protocols • Unbiased testing of competitive equipment

Pre-delivery Services:

On-site Services:

• Validation support

• Installation qualification

• Consultation

• Operational qualification

• Factory Acceptance Testing

• Performance qualification

• Calibration

• Calibration

• Temperature mapping

• Temperature mapping

Panasonic Healthcare Corporation of North America 1300 Michael Drive, Suite A, Wood Dale, IL 60191 Toll Free USA (800) 858-8442, Fax (630) 238-0074 us.panasonic-healthcare.com Š Panasonic Printed in USA | 06/2014 AG