Antimicrobial Drugs - Treatment of Bacterial Infection

1 Antimicrobial Drugs - Treatment of Bacterial Infection Treatment of Bacterial Infection Bacterial infections are treated using antibiotics. An example of a common bacterial infection treated with antibiotics is gonorrhea. However, different strains of Neisseria gonorrhoeae, the bacteria responsible for gonorrhea, have emerged. These strains are treated with a combination of stronger antibiotics. Treatment of uncomplicated gonorrhea is usually done with a combination of ceftriaxone and azithromycin. Monotherapy is not recommended since the bacteria can easily develop resistance towards the drug. Ceftriaxone is usually given as an intramuscular or intravenous injection.

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The symptoms of gonorrhea cease after a few days of treatment. The failure to stop is an indication of a complex condition that requires stronger antibiotics (CDC, 2020). For a better outcome of care, all sexual partners of a person diagnosed with gonorrhea must be treated.

Treatment of sexual partners should be done even if they do not present with symptoms to prevent reinfection once through with treatment (Stanhope & Lancaster, 2019).

Ceftriaxone is effective in the treatment of gonorrhea since it targets and selectively inhibits the synthesis of the cell wall (Rosenthal & Burchum, 2017). Azithromycin, on the other hand, stops the bacterial growth by decreasing the bacterial cell production of proteins. Although no drug interactions have been reported due to the use of ceftriaxone and azithromycin in the treatment of gonorrhea this does not mean that an individual is free of side effects (Rosenthal & Burchum, 2017). Oral antibiotics can cause changes in the normal flora in the gastrointestinal system. Some individuals may, subsequently, suffer from yeast infections or gastrointestinal symptoms such as diarrhea, nausea, and vomiting. Stomach upset, allergic reactions and rashes may also be reported by some people (Rosenthal & Burchum, 2017). Since antibiotics for gonorrhea are usually taken for a maximum of 14 days, the side effects are mild and cease once treatment is terminated.

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References CDC (2020). Gonorrhea Treatment and Care. https://www.cdc.gov/std/gonorrhea/treatment.htm Jamieson (2018). Azithromycin: The Ultimate Treatment, Uses, Side Effects, and Herbal Remedy of Bacterial Infection Using Azithromycin Tablet. CreateSpace Independent Publishing Platform.

4 Rosenthal, L., & Burchum, J. (2017). Lehne’s Pharmacotherapeutics for Advanced Practice Nurses and Physician Assistants-E-Book. Elsevier Health Sciences.

Stanhope, M., & Lancaster, J. (2019). Public health nursing e-book: Population-centered health care in the community. Elsevier Health Sciences