1 Long-term Effects of Harmful Substances on the Respiratory System Introduction The respiratory system is prone to harm that may result from hazardous substances that may be contained in the air. These harmful substances may come naturally from the environment, out of a polluted environment, due to risky lifestyles as well as in the form of occupational hazards. Exposure to hazardous substances such as asbestos, smoke (from tobacco or marijuana) and automotive exhaust may result into severe long-term effects on the respiratory system. Some of the long term effects include lung cancer, tuberculosis, respiratory failure, asthma and asbestosis. Lifestyle, Environmental and Occupational Hazards According to the National Cancer Institute (2010), smoking predisposes individuals to lung cancer which leads to many deaths. For instance, 90% of deaths resulting from lung cancer in the United States are due to smoking. This is regardless of whether one is exposed to direct or passive smoke. The smoke may be from cigarettes or from marijuana.
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