1 The Opioid Crisis in the United States The opioid crisis in the United States started in the 1990s following the increased prescription of opioid-containing medications to treat chronic pain. The pharmaceutical companies had reassured healthcare professionals that users could not become addicted to pain relievers containing opioids. However, increased prescriptions of these medications contributed to the pervasive misuse of prescription and non-prescription opioids. These drugs trigger endorphin release in the brain, thus, generating feelings of pleasure and a powerful sense of wellbeing. When the effects wear off, a person is overwhelmed by the desire to consume more opioids to maintain the pleasurable feeling. Anyone who takes substances containing opioids is at risk of developing an addiction. The risk is, however, determined by the dose and the duration one uses these substances. Unfortunately, it is impossible to predict the people vulnerable to eventual addiction upon using these drugs.
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