His diagnosis is of exclusion. erythema annulare centrifugum ( eac), like urticaria or erythema multiforme, is a reactive condition that can result from multiple immunologic stimuli or other systemic perturbations of homeostasis, even conditions such as pregnancy. centrifugo figure 1 414 the american journal of the medical sciences volume 347, number 5, may. when erythema annulare centrifugum occurs as part of a paraneoplastic phenomenon, it is called paraneoplastic erythema annulare centrifugum eruption ( peace). new concepts on erythema annulare centrifugum: a clinical reaction pattern that does not represent a speci■c clinicopathological entity. br j dermatol ; 160: 119– 26. from: urgent care dermatology: symptom- based diagnosis, view all topics add to mendeley about this page. it has two variant surface and deep. erythema annulare centrifugum ( eac) is a chronic, reactive phenomenon of the skin presenting with arcuate or annular, erythematous patches or thin plaques that frequently exhibit scale eritema along the inner portion of anulare the advancing edge of lesions ( " trailing scale" pdf ) ( picture 1a- d ). eac has been reported to occur in association with a wide variety. erythema annulare centrifugum is classified as a reactive erythema and has been associated with many different conditions, including malignancy. erythema annulare centrifugum, is an inflammatory disease characterized by presenting a clinical pattern of erythematous rings that expand into circles that enlarge rapidly, then decrease and finally disappear as new lesions appear. ziemer m, eisendle k, zelger eritema anulare centrifugo pdf b.