30. Who should not take resveratrol

nd oxidative stress. Resveratrol’s health benefits have also been shown in ma ny other studies, and even meta-analyses.

When it comes to pterostilbene, the evidence is much sparser. Aside from a safety study published in 2013, there have been very few trials conducted in humans. There was one study, conducted at the University of Mississippi in 8 0 adults, which found that pterostilbene supported healthy blood pressure an d lipid metabolism.

The vast majority of research on pterostilbene is in the experimental and pre clinical phase. Researchers have found that pterostilbene supports many of th e same cellular pathways as resveratrol—including supporting antioxidant defe nses and modulating pathways involved in healthy inflammatory balance, apop tosis, and autophagy. Most experts agree that the molecular mechanisms of p terostilbene should be considered equivalent to those of resveratrol.

Patients who have blood disorders, which can cause bleeding, should be moni tored by a physician while taking this product. People undergoing surgery sho uld stop taking resveratrol two weeks before the surgery and not take it for two weeks after the surgery to reduce the risk of bleeding.

Do not take resveratrol supplements or excessive amounts of natural foods co ntaining resveratrol while pregnant or breast-feeding. There is a lack of resear ch in this area to prove safety. Resveratrol should be avoided in children.

Resveratrol has mild estrogenic activity and until more is known, women with cancers and other conditions that are estrogen sensitive should seek medical advice before taking resveratrol.

Resveratrol reduces the activity of enzymes involved with drug metabolism bu t whether it has a significant effect in humans has not been studied.