MANUFACTURING
Additive Manufacturing as a Problem-Solving Tool in Pharmaceutical Processing A hybrid raxial mixing impeller is designed and implemented to resolve dispersion mixing issues in a pharmaceutical application While process automation, a core tenet of the transition to Industry 4.0, can minimize or eliminate processing issues associated with a wide range of material variability, some variations require physical alterations to processing equipment to be implemented. In this article segregation issues caused by an API supplier-change are addressed rapidly and efficiently via another pillar of Industry 4.0, additive manufacturing. Chris O’Callaghan*
Patrick Cronin
Innopharma Technology Ltd.
Department of Chemical Sciences and Bernal Institute, University of Limerick
Caroline McCormack Innopharma Technology Ltd.
Sam Solomon
Ian Jones Innopharma College of Applied Sciences Ltd.
Department of Chemical Sciences and Bernal Institute, University of Limerick
A
t the core of the transition to Industry 4.0 is the drive toward robust, reliable and comprehensive process automation. Three of the nine pillars of Industry 4.0 : Internet of Things, System Integration and Autonomous Robotics are particularly well suited to supporting this objective. With effective and democratised automation delivered by a range of available process digitalisation platforms, processing issues such as those caused by raw material variability from supplier or up-stream processing steps can often be addressed with no quality or time penalties.
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P H AR M A F O C U S E U R O PE
ISSUE 01 - 2022
