The Bernal Institute Report 2020

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Research Highlights Bernal Institute secured €2.5m in European Research Council funding

‘By making simple changes, we can have a positive impact on climate change’ Professor JJ Leahy JJ Leahy, associate professor in UL’s Department of Chemical Sciences and a member of the Bernal Institute, is the energy and transport expert for the RTE TV Series ‘What Planet Are You On’, which focuses on getting households to take part in the fight against Bernal Chair in Pharmaceutical Powder Engineering, Professor Gavin Walker

climate change by reducing their carbon footprint. Professor Leahy has a strong background in circular bioeconomy and applied biofuels research;

Bernal Chair in Crystal Engineering, Professor Michael Zaworotko

he is associated with MaREI – the SFI Research Bernal Chair of Pharmaceutical Powder Engineering

Centre for Energy, Climate and Marine - and

and Co-Director of SSPC, Professor Gavin Walker,

SFI’s Bioeconomy centre. This collaboration with

In March 2020 Bernal Chair in Crystal Engineering

will receive €1.9m to develop a national advanced

industry and commitment to reducing our carbon

Michael Zaworotko was awarded almost €2.5m in

drug product manufacturing facility to facilitate

footprint has led to two start-up biofuel companies

ERC Advanced Grant funding. University of Limerick

industrial collaboration and support SSPC research

as well as currently leading two EU projects on the

received two awards of €2.5m each, these are the first

projects with industrial and academic partners.

Circular Bioeconomy, REFLOW and BIOWILL.

ERC Advanced Grants to be hosted at the University.

Professor Walker will lead the team helping to bridge

In total €450 million was awarded for long-term

the challenging engineering and scientific gap for

REFLOW involves academic and industrial

frontier research to 185 researchers by the ERC, the

process scale-up from lab to manufacturing.

organisations in seven countries, focusing

premiere European funding organisation, as part of the

on the recycling of phosphorous from the

EU research and innovation programme Horizon 2020.

“The move towards continuous manufacturing

wastewater solids in dairy factories and using

will be the next major innovation for the

it as a CE marked fertilizer components.

Professor Michael Zaworotko, Bernal Chair of

pharmaceutical industry and it’s essential that

Crystal Engineering and Science Foundation Ireland

the Irish pharmaceutical manufacturing industry

The BIOWILL project aims to be a flagship for rural

Research Professor at University of Limerick’s

move towards continuous processing to remain

Ireland through a zero-waste biorefinery utilising all

globally competitive.” said Professor Walker.

parts of willow trees to produce high to medium based

Bernal Institute, was awarded almost €2.5m for

“These processes collectively use around 20%

his project ‘SYNSORB – SYNergistic SORBents’.

of global energy supplies and demand for water

Professor Zaworotko, said his project “will address the

and industrial commodities continues to grow. Our

“The implementation of continuous pharmaceutical

form of biomethane production and natural fertilisers.

high energy footprint of gas and vapour purification by

goal is to discover and develop new sorbents that

processes is an opportunity to substantially

BioWILL was awarded €909,057 from Interreg

single-step purification processes that involve the use

reduce the energy footprint of these processes by

reduce costs, reduce manufacturing times and

North-West Europe Programme, the project consists

of a new generation of solid materials called sorbents.

50-90%, thereby significantly reducing the energy

bring medicines quickly to market, improve

of 10 partners in four countries across Europe.

and, in turn, carbon footprint of these processes.”

product defects, and encourage innovation by

“These sorbents act like sponges for impurities

biochemicals/materials and renewable energy in the

an integrated manufacturing approach.”

by capturing them spontaneously and releasing

ERC Advanced Grants support established,

them upon mild heating.

leading principal investigators that want long-

“This research infrastructure, will build on

term funding to pursue a ground-breaking, high-

the University of Limerick’s reputation of

“The most important vapour is water vapour. Water

risk project. Advanced Grants may be awarded

internationally leading research in pharmaceutical

vapour is everywhere in the atmosphere, even in the

up to €2.5 million for a period of 5 years.

manufacturing at the Bernal Institute.”

Professor JJ Leahy

most arid regions, but harvesting pure water from The new Advanced Drug Product Manufacturing

water vapour using existing desiccants uses so much

Advanced Drug Product Manufacturing Facility to be developed at Bernal Institute

Facility will deliver a suite of next generation process

“Gases such as CO2 and acetylene are impurities in

SSPC, the Science Foundation Ireland (SFI)

environment; an addition to SSPC’s significant

commodity production and must be removed using

Research Centre for Pharmaceuticals, hosted

capability in upstream continuous processing for

processes that typically involve chemical reactions.

at the Bernal Institute, will soon have access

active pharmaceutical ingredient production.

energy that it is not commercially viable despite the water stresses faced by much of humanity.

equipment to foster industrial collaboration on drug product manufacturing within the academic

to a suite expanding the research capabilities at UL through SFI Infrastructure Awards. 42

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