Twintig jaar Julius Centum

JULIUS CENTER WHAT HAS BECOME OF OUR PHD STUDENTS

UMC Utrecht Julius Center

Index Class of 1996 - 2001

5

Class of 2002

25

Class of 2003

41

Class of 2004

55

Class of 2005

69

Class of 2006

89

Class of 2007

109

Class of 2008

119

Class of 2009

143

Class of 2010

161

Class of 2011

181

Class of 2012

203

Class of 2013

227

Class of 2014

247

Class of 2015

273

Class of 2016

301

Class of 2017

333

Class of

1996 - 2001

6 20 years Julius Center; 1996-2017

1996 Name Margreet Pols PhD defense December 17th, 1996 PhD team Grobbee, Peeters Speciality Senior advisor (quality management) Deputy Director Position Department Knowledge Institute of Medical Specialists (Kennisinstituut van Medisch Specialisten) Dutch Federation Medical Specialists Location City Utrecht The Netherlands Country Quote “Treat others the same way you want them to treat you” MAIN PAPER Pols MA, Peeters PH, Twisk JW, Kemper HC, Grobbee DE. Physical activity and cardiovascular disease risk profile in women. Am J Epidemiol. 1997 Aug 15;146(4):322-8. PubMed PMID: 9270411.

1997 Name Marjon Kallewaard PhD defense October 31st, 1997 PhD team Grobbee, van der Graaf Quality in Health Indicators Speciality Director of Quality Position Department Council of Quality Location Dutch Federation Medical Specialists City Utrecht Country The Netherlands Quote “...”

MAIN PAPER van Gorp MJ, Steyerberg EW, Kallewaard M, van der Graaf Y. Clinical prediction rule for 30-day mortality in Björk-Shiley convexoconcave valve replacement. J Clin Epidemiol. 2003 Oct;56(10): 1006-12. PubMed PMID: 14568633.

20 years Julius Center; 1996-2017 7

1997 Name Mike Liem PhD defense June 6th, 1997 van Vroonhoven, van der Graaf PhD team Speciality Hepato-Pancreato-Biliairy Surgery, Colorectal and Laparoscopic surgery Position Surgeon Department Surgery Location Medisch Spectrum Twente City Enschede Country The Netherlands Quote “...”

MAIN PAPER Liem MS, van der Graaf Y, van Steensel CJ, Boelhouwer RU, Clevers GJ, Meijer WS, et al. Comparison of conventional anterior surgery and laparoscopic surgery for inguinal-hernia repair. N Engl J Med. 1997 May 29;336(22):1541-7. PubMed PMID: 9164809.

1997 Name Eric Tetteroo PhD defense May 20th, 1997 PhD team Grobbee, van der Graaf, Hunink Speciality Radiology Position Radiologist Department Radiology Location Amphia Hospital City Breda Country The Netherlands Quote “...”

MAIN PAPER Tetteroo E, van der Graaf Y, Bosch JL, van Engelen AD, Hunink MG, Eikelboom BC, Mali WP. Randomised comparison of primary stent placement versus primary angioplasty followed by selective stent placement in patients with iliac-artery occlusive disease. Dutch Iliac Stent Trial Study Group. Lancet. 1998 Apr 18;351(9110):1153-9.

PubMed PMID: 9643685.

8 20 years Julius Center; 1996-2017

1998 Name Jan Assink PhD defense February 18th, 1998 PhD team Grobbee, Bilo Speciality Internal Medicine & Diabetology Position Internist Department Internal Medicine Maasstad Hospital Location City Rotterdam Country The Netherlands Quote “...”

MAIN PAPER Hart HE, Bilo HJ, Redekop WK, Stolk RP, Assink JH, Meyboom-de Jong B. Quality of life of patients with type I diabetes mellitus. Qual Life Res. 2003 Dec;12(8):1089-97. PubMed PMID: 14651426.

1998 Name Tanneke Gerritsen PhD defense January 27th, 1998 PhD team Grobbee, Bak General Practice Speciality General Practitioner Position Department Location Puttershoek Medical Center City Puttershoek Country The Netherlands Quote “...”

MAIN PAPER Gerritsen TA, Bak AA, Stolk RP, Jonker JJ, Grobbee DE. Effects of nitrendipine and enalapril on left ventricular mass in patients with non-insulin-dependent diabetes mellitus and hypertension.

J Hypertens. 1998 May;16(5):689-96. PubMed PMID: 9797181.

20 years Julius Center; 1996-2017 9

1998 Name Alexander Montauban van Swijndregt PhD defense April 28th, 1998 Mali, van der Graaf, Ackerstaff PhD team Speciality Radiology Position Intervention Radiologist Department Radiology Location Onze Lieve Vrouwe Gasthuis City Amsterdam Country The Netherlands Quote “...”

MAIN PAPER Zijta FM, Florie J, Jensch S, Bipat S, Nievelstein RA, Poulus M, et al. Diagnostic performance of radiographers as compared to radiologists in magnetic resonance colonography. Eur J Radiol.

2010 Aug;75(2):e12-7. PubMed PMID: 19926419.

1999 Name Jan Willem Gorter PhD defense November 16th, 1999 PhD team van Gijn, Algra Speciality Physical Medicine and Rehabilitation Position Professor, Scotiabank Chair in Child Health Research, Director CanChild Department Pediatrics & School of Rehabilitation Science Location McMaster University City Hamilton, Ontario Country Canada Quote “Treating complex conditions requires us to work together – it’s a big puzzle and no one has all of the pieces. We need to work in partnership, and that includes patients and families” MAIN PAPER The Stroke Prevention in Reversible Ischemia Trial (SPIRIT) Study Group. A randomized trial of anticoagulants versus aspirin after cerebral ischemia of presumed arterial origin. Ann Neurol 1997;42:857-65. PubMed PMID: 9403477 10 20 years Julius Center; 1996-2017

1999 Name Nicoline van den Broek PhD defense October 1st, 1999 PhD team Verheij, Smout, Numans, Buskens Speciality General Practice Position Vice director Bachelor and Master Education Medical Students Department General Practice University Medical Center Groningen Location City Groningen The Netherlands Country “Onder druk wordt alles vloeibaar” Quote MAIN PAPER Lewin van den Broek NT, Numans ME, Buskens E, Verheij TJ, de Wit NJ, Smout AJ. A randomised controlled trial of four management strategies for dyspepsia: relationships between symptom subgroups and strategy outcome. Br J Gen Pract. 2001 Aug;51(469):619-24. PubMed PMID: 11510389;

1999 Otto Quartero Name PhD defense November 9th, 1999 de Melker, de Wit PhD team General Practice Speciality General Practitioner Position Department Location Own General Practice City Diepeveen Country The Netherlands Quote “...”

MAIN PAPER Quartero AO, Burger H, Donker M, de Wit NJ. Exercise therapy for stress-related mental disorder, a randomised controlled trial in primary care. BMC Fam Pract. 2011 Jul 26;12:76. PubMed PMID: 21791041;

20 years Julius Center; 1996-2017 11

1999 Name Mark Roest PhD defense November 25th, 1999 PhD team Grobbee, Sixma, van der Schouw,Banga Speciality Epidemiology of Biomarkers Position Head Clinical Laboratory Department Location Synapse Research Institute City Maastricht Country The Netherlands Quote “Onderzoek moet leuk zijn” MAIN PAPER Roest M, Banga JD, Grobbee DE, de Groot PG, Sixma JJ, Tempelman MJ, van der Schouw YT. Homozygosity for 807 T polymorphism in alpha(2) subunit of platelet alpha(2)beta(1) is associated with increased risk of cardiovascular mortality in high-risk women.

Circulation. 2000 Oct 3;102(14):1645-50. PubMed PMID: 11015342.

1999 Name Petra Simons PhD defense February 5th, 1999 PhD team Grobbee, van der Graaf, Algra Speciality Radiology Position Radiologist Department Radiology Location VieCuri Medical Center City Venlo Country The Netherlands Quote “...”

MAIN PAPER Lips LM, Cremers PT, Pickhardt PJ, Cremers SE, Janssen-Heijnen ML, de Witte MT, Simons PC. Sigmoid cancer versus chronic diverticular disease: differentiating features at CT colonography. Radiology.

2015 Apr;275(1):127-35. PubMed PMID: 25426771.

12 20 years Julius Center; 1996-2017

1999 Name Mirjam de Valk PhD defense December 10th, 1999 PhD team Schrijvers, Cools Speciality Business Management Senior Consultant Position Department Zorg Innovation Forum Location City Groningen Country The Netherlands Quote “...”

MAIN PAPER De Valk MM, Oostrom C, Schrijvers AJ. An assessment of occupational health care in the Netherlands (1996-2005). Occup Med (Lond).

2006 Oct;56(7):475-9.PubMed PMID: 16896055.

1999 Name Sjoerd Zwart PhD defense June 24th, 1999 PhD team de Melker, Rietveld, Sachs General Practice Speciality General Practitioner Position Department Location Berent Avercamp Health Care Center City Kampen Country The Netherlands “Patients ask for prognosis, not for penicillin“ Quote MAIN PAPER Zwart S, Sachs AP, Ruijs GJ, Gubbels JW, Hoes AW, de Melker RA. Penicillin for acute sore throat: randomised double blind trial of seven days versus three days treatment or placebo in adults. BMJ. 2000 Jan 15;320(7228):150-4. PubMed PMID: 10634735

20 years Julius Center; 1996-2017 13

2000 Name Irma van den Arend PhD defense December 12th, 2000 PhD team Schrijvers, Rutten, Stolk Speciality Health Economics, Pricing and Reimbursement Position Lead Market Access Oncology Western Europe & Canada Department Location AbbVie Pharmaceuticals City Paris Country France Quote “...”

MAIN PAPER van den Arend IJ, Stolk RP, Rutten GE, Schrijvers GJ. Education integrated into structured general practice care for Type 2 diabetic patients results in sustained improvement of disease knowledge and self-care. Diabet Med. 2000 Mar;17(3):190-7. PubMed PMID: 10784222.

2000 Name Roger Damoiseaux PhD defense June 15th, 2000 PhD team de Melker, van Balen Speciality General Practice Position General Practitioner, Professor, Chair of department Department General Practice , Julius Center for Health Sciences and Primary Care Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “...”

MAIN PAPER Damoiseaux RA, van Balen FA, Hoes AW, Verheij TJ, de Melker RA. Primary care based randomised, double blind trial of amoxicillin versus placebo for acute otitis media in children aged under 2 years. BMJ. 2000 Feb 5;320(7231):350-4.PubMed PMID: 10657332.

14 20 years Julius Center; 1996-2017

2000 Name Otto Elgersma PhD defense October 10th, 2000 PhD team Eikelboom, Mali, van der Graaf Speciality Radiology Position Radiologist Department Radiology Albert Schweitzer Hospital Location City Dordrecht Country The Netherlands Quote “...”

MAIN PAPER Elgersma OE, Wüst AF, Buijs PC, van Der Graaf Y, Eikelboom BC, Mali WP. Multidirectional depiction of internal carotid arterial stenosis: three-dimensional time-of-flight MR angiography versus rotational and conventional digital subtraction angiography. Radiology. 2000 Aug;216(2):511-6. PubMed PMID: 10924579.

2000 Name Johan Feenstra PhD defense September 13th, 2000 PhD team Grobbee, Stricker General Practice Speciality General Practitioner Position Department Location General Practice Stad and Ambt Sint Jansklooster City Country The Netherlands Quote “...”

MAIN PAPER Feenstra J, Grobbee DE, Remme WJ, Stricker BH. Drug-induced heart failure. J Am Coll Cardiol. 1999 Apr;33(5):1152-62. PubMed PMID: 10193711.

20 years Julius Center; 1996-2017 15

2000 Suzanne Geerlings Name PhD defense May 23th, 2000 PhD team Hoepelman, Gaastra, Stolk Speciality Internal Medicine - Infectious Disease Position Professor of Internal Medicine, with emphasis on Quality of Care Department Internal Medicine & Infectious Disease Location University of Amsterdam & Academic Medical Center Amsterdam City Amsterdam Country The Netherlands Quote “...”

MAIN PAPER van Daalen FV, Prins JM, Opmeer BC, Boermeester MA, Visser CE, van Hest RM,et al. Effect of an antibiotic checklist on length of hospital stay and appropriate antibiotic use in adult patients treated with intravenous antibiotics: a stepped wedge cluster randomized trial. Clin Microbiol Infect. 2017 Jan 31. pii: S1198743X(17)30072-1. PubMed PMID: 28159671.

2000 Name Miriam de Kleijn PhD defense January 28th, 2000 PhD team Grobbee, van der Schouw Speciality General Practice Position General Practitioner Department Location Health Care Center Diemen City Diemen Country The Netherlands Quote “...”

MAIN PAPER de Kleijn MJ, van der Schouw YT, Wilson PW, Adlercreutz H, Mazur W, Grobbee DE, Jacques PF. Intake of dietary phytoestrogens is low in postmenopausal women in the United States: the Framingham study(1-4). J Nutr. 2001 Jun;131(6):1826-32. PubMed PMID: 11385074.

16 20 years Julius Center; 1996-2017

2000 Name Myrthe Kok PhD defense May 9th, 2000 PhD team Grobbee, van der Tweel, Boon Speciality Radiotherapy Deceased October 30th, 2009 Position Department Radiotherapy VU University Medical Center Amsterdam Location City Amsterdam Country The Netherlands Quote “...”

MAIN PAPER Kok MR, Boon ME, Schreiner-Kok PG, Hermans J, Grobbee DE, Kok LP. Less medical intervention after sharp demarcation of Grade 1-2 cervical intraepithelial neoplasia smears by neural network screening. Cancer. 2001 Jun 25;93(3):173-8. PubMed PMID: 11391604.

2000 Name Suzan Niemeijer-Kanters PhD defense February 25th, 2000 PhD team Erkelens, Banga, Algra Vascular Medicine Speciality Internist-Vascular Medicine Position Department Internal Medicine Location Antonius Hospital City Sneek Country The Netherlands “Life is what you make it” Quote MAIN PAPER Niemeijer-Kanters SD, Dallinga-Thie GM, de Ruijter-Heijstek FC, Algra A, Erkelens DW, Banga JD, Jansen H. Effect of intensive lipid-lowering strategy on low-density lipoprotein particle size in patients with type 2 diabetes mellitus. Atherosclerosis. 2001 May;156(1):209-16.

20 years Julius Center; 1996-2017 17

2000 Name Marco Tangelder PhD defense May 22th, 2000 PhD team Eikelboom, Algra, Lawson Speciality Clinical development lead gene therapy for hemophilia B Position Senior Medical Director UniQure & Panta Rei Cardiovascular R&D Consultancy Department Location UniQure City Amsterdam Country The Netherlands Quote “...”

MAIN PAPER Dutch Bypass Oral anticoagulants or Aspirin (BOA) Study Group.

Efficacy of oral anticoagulants compared with aspirin after infrainguinal bypass surgery (The Dutch Bypass Oral Anticoagulants or Aspirin Study): a randomised trial. Lancet 2000;355:346-51. Writing committee: Tangelder MJD, Algra A, Lawson JA, Eikelboom BC. PubMed PMID: 10665553

2000 Name Lenny Verkooijen PhD defense December 8th, 2000 PhD team Van Vroonhoven, Mali, Peeters, Borel Rinkes Speciality Clinical Epidemiology of Cancer Position Associate Professor Department Radiology Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “Life is what happens to you while you’re busy making other plans“ - John Lennon MAIN PAPER Verkooijen HM; Core Biopsy After Radiological Localisation (COBRA) Study Group. Diagnostic accuracy of stereotactic large-core needle biopsy for nonpalpable breast disease: results of a multicenter prospective study with 95% surgical confirmation. Int J Cancer.

2002 Jun 20;99(6):853-9. PubMed PMID: 12115488.

18 20 years Julius Center; 1996-2017

2000 Name Gerdien Weert – van Oene PhD defense November 2th, 2000 PhD team Schrijvers, Schippers, de Jong Speciality Clinical Psychology with emphasis on Addition Senior Researcher Position Department Victas, Center for Addiction Treatment & Nijmegen Institute for Scientist-Practitioners in Addiction NISPA Location Utrecht & Radboud University Medical Center City Nijmegen The Netherlands Country Quote “...”

MAIN PAPER De Weert-Van Oene GH, Markus W, Kissane DW, De Jong CA. Demoralization in patients with substance use and co-occurring psychiatric disorders. J Dual Diagn. 2017 Jan 27:0. PubMed PMID: 28129100.

2001 Name Kathelijn Fischer PhD defense October 5th, 2001 Grobbee, van den Berg, van der Bom PhD team Speciality Epidemiology of coagulation disorders, especially haemophilia Epidemiologist, Pediatrician-haematologist Position Department Internal Medicine, van Creveldt Clinic University Medical Center Utrecht Location City Utrecht The Netherlands Country Quote “...”

MAIN PAPER Fischer K, Pinho Dos Reis V, Balkema-Buschmann A. Bat Astroviruses: Towards Understanding the Transmission Dynamics of a Neglected Virus Family. Viruses. 2017 Feb 21;9(2). pii: E34. PubMed PMID: 28230787.

20 years Julius Center; 1996-2017 19

2001 Kees Gorter Name PhD defense October 2th, 2001 PhD team de Melker, Kuyvenhoven Speciality General Practice Position General Practitioner Department General Practice , Julius Center for Health Sciences and Primary Care Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “...”

MAIN PAPER Gorter KJ, Tuytel GJ, de Leeuw RR, Bensing JM, Rutten GE. Opinions of patients with type 2 diabetes about responsibility, setting targets and willingness to take medication. A cross-sectional survey.

Patient Educ Couns. 2011 Jul;84(1):56-61. PubMed PMID: 20655164

2001 Name Jeanet Kemmeren PhD defense June 1st, 2001 PhD team Grobbee, Algra Speciality Epidemiology Position Senior Epidemiologist Department Centre for Infectious Disease Control Location National Institute for Public Health and the Environment (RIVM) City Bilthoven Country The Netherlands Quote “Logica brengt je van A naar B. Verbeelding brengt je overal” - A. Einstein MAIN PAPER Kemmeren J, Honsbeek M, Dijkstra F, de Lange M, van der Maas N, Smallenburg R,Koppeschaar C, van der Hoek W. Comparison of different collection methods for reported adverse events following pandemic and seasonal influenza vaccination. Vaccine. 2016 Jul 25;34(34):3961-6. PubMed PMID: 27349839.

20 20 years Julius Center; 1996-2017

2001 Name Eelko Hak PhD defense September 11th, 2001 PhD team Hoes, Verheij Speciality Pharmacoepidemiology Professor of Clinical Pharmacoepidemiology Position Department Faculty of Mathematics and Physical Sciences & Department of Epidemiology Location University of Groningen & University Medical Center Groningen City Groningen The Netherlands Country Quote “...”

MAIN PAPER Darvishian M, van den Heuvel ER, Bissielo A, Castilla J, Cohen C, Englund H,et al. Effectiveness of seasonal influenza vaccination in community-dwelling elderly people: an individual participant data meta-analysis of test-negative design case-control studies. Lancet Respir Med. 2017 Mar;5(3):200-211. PubMed PMID: 28189522.

2001 Name Barbara van der Linden PhD defense April 20th, 2001 Schrijvers, Spreeuwenberg PhD team Implementation of research Speciality Staff member implementation at ZonMw Position Department Institute of Social Medicine Location The Netherlands Organisation for Health Research and Development (ZonMw) The Hague City The Netherlands Country Quote ”Yes we can” MAIN PAPER van der Linden BA, Spreeuwenberg C, Schrijvers AJ. Integration of care in The Netherlands: the development of transmural care since 1994. Health Policy. 2001 Feb;55(2):111-20. PubMed PMID: 11163650.

20 years Julius Center; 1996-2017 21

2001 Name Evert Meijer PhD defense November 21st, 2001 PhD team Grobbee, Brunekreef, Heederik Speciality Environmental Health Epidemiology Position We were inable to obtain information through internet and/or personal contact Department Location City Country Quote MAIN PAPER Suarthana E, Vergouwe Y, Moons KG, de Monchy J, Grobbee D, Heederik D, Meijer E. A diagnostic model for the detection of sensitization to wheat allergens was developed and validated in bakery workers. J Clin Epidemiol. 2010 Sep;63(9):1011-9. PubMed PMID: 20189762.

2001 Name Rianne Oostenbrink PhD defense June 13th, 2001 PhD team Grobbee, Büller, Moll Speciality Pediatric Medicine Position Associate Professor of Pediatrics Department General Pediatrics Location Erasmus Medical Center City Rotterdam Country The Netherlands Quote “To finish first, one first got to finish” - van Ron Dennis, F1 McLaren team MAIN PAPER Oostenbrink R, Oostenbrink JB, Moons KG, Derksen-Lubsen G, Grobbee DE, Redekop WK, Moll HA. Application of a diagnostic decision rule in children with meningeal signs: a cost-minimization study. Int J Technol Assess Health Care. 2003 Fall;19(4):698-704.

PubMed PMID: 15095776.

22 20 years Julius Center; 1996-2017

2001 Name Sanne Veltkamp PhD defense November 30th, 2001 PhD team Van der Werken, van der Graaf Speciality Surgery Position Surgeon Department Surgery Amstelland Hospital Location City Amstelveen Country The Netherlands “Count your blessings… “ Quote MAIN PAPER Veltkamp SC, Kemmeren JM, van der Graaf Y, Edlinger M, van der Werken C. Prediction of serious complications in patients admitted to a surgical ward. Br J Surg. 2002 Jan;89(1):94-102. PubMed PMID: 11851672.

2001 Name Marjolein van Vliet PhD defense April 24th, 2001 PhD team Grypdonck, Winnubst, Zuuren Nursing Sciences Speciality Expert on quality, effectivenss and safety of care Position Department Location Vilans: Center for Expertise for Long Term Care City Utrecht Country The Netherlands Quote “Nursing Science investigates how vulnerable patients and their relatives can deal with invasive medical procedures and demanding diseases” MAIN PAPER Van Achterberg T, Holleman G, Van de Ven M, Grypdonck MH, Eliëns A, van Vliet M. Promoting evidence-based practice: the roles and activities of professional nurses’ associations. J Adv Nurs. 2006 Mar;53(5):605-12. PubMed PMID: 16499681.

20 years Julius Center; 1996-2017 23

Class of

2002

2002 Name Sacha Bleeker PhD defense September 1th, 2002 PhD team De Groot, Grobbee, Moll, Moons Speciality Cardiopulmonary Rehabilitation Position Physician Cardiopulmonary Rehabilitation Department Location Rijnlands Revalidatie Center City Leiden Country The Netherlands Quote “Externe validatie van een diagnostische beslisregel die gebaseerd is op een relatief kleine dataset is ondanks interne validiteit essentieel vóór implementatie in de klinische praktijk” MAIN PAPER Bleeker SE, Moll HA, Steyerberg EW, Donders AR, Derksen-Lubsen G, Grobbee DE, Moons KG. External validation is necessary in prediction research: a clinical example. J Clin Epidemiol. 2003 Sep;56(9):826-32. PubMed PMID: 14505766.

2002 Daisy Bloemenkamp Name PhD defense May 31st, 2002 Van der Graaf, Mali, Visseren PhD team Speciality Radiology Position Radiologist Department Radiology Meander Medical Center Location City Amersfoort Country The Netherlands Quote “...”

MAIN PAPER Bloemenkamp DG, Mali WP, Tanis BC, Rosendaal FR, van den Bosch MA, Kemmeren JM, et al. Chlamydia pneumoniae, Helicobacter pylori and cytomegalovirus infections and the risk of peripheral arterial disease in young women. Atherosclerosis. 2002 Jul;163(1):149-56. PubMed PMID: 12048133.

20 years Julius Center; 1996-2017 27

2002 Name Maurice van den Bosch PhD defense January 22th, 2002 PhD team Mali, van der Graaf Speciality Interventioal Radiology Position Professor & Member of the Executive Board OLVG Department Radiology Location Onze Lieve Vrouwe Gasthuis City Amsterdam Country The Netherlands Quote “...”

MAIN PAPER Van Den Bosch MA, Kemmeren JM, Tanis BC, Mali WP, Helmerhorst FM, Rosendaal FR, Algra A, Van Der Graaf Y. The RATIO study: oral contraceptives and the risk of peripheral arterial disease in young women. J Thromb Haemost. 2003 Mar;1(3):439-44. PubMed PMID: 12871447.

2002 Name Marcel Bouvy PhD defense March 18th, 2002 PhD team Leufkens, Hoes, Heerdink Speciality Pharmacy Position Professor of Pharmaceutical Care & Pharmacist Department Pharmaceutical Sciences Location Utrecht University & Stevenshof Pharmacy City Utrecht & Leiden Country The Netherlands Quote “...”

MAIN PAPER Notenboom K, Leufkens HG, Vromans H, Bouvy ML. Learning from patients: Identifying design features of medicines that cause medication use problems. Int J Pharm. 2017 Jan 30;517(1-2):128134. PubMed PMID: 27931784.

28 20 years Julius Center; 1996-2017

2002 Name Derk Brouwer PhD defense March 11th, 2002 PhD team Brunekreef, Heerderik, van Hemmen Speciality Epidemiology of Occupational Exposures Professor, Chair in Occupational Hygiene Position Department Occupational Hygiene University of Witwatersrand Location City Johannesburg Country South Africa Quote “...”

MAIN PAPER Van-Wendel-de-Joode B, Brouwer DH, Vermeulen R, Van Hemmen JJ, Heederik D,Kromhout H. DREAM: a method for semi-quantitative dermal exposure assessment. Ann Occup Hyg. 2003 Jan;47(1):71-87.

PubMed PMID: 12505908.

2002 Name Diederik van Dijk PhD defense October 22nd, 2002 PhD team Kalkman, Grobbee, de Jaegere Intensive Care Medicine Speciality Position Professor Department Anaesthesiology and Intensive Care Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “...”

MAIN PAPER Van Dijk D, Jansen EW, Hijman R, Nierich AP, Diephuis JC, Moons KG, et al. Octopus Study Group. Cognitive outcome after off-pump and on-pump coronary artery bypass graft surgery: a randomized trial.

JAMA. 2002 Mar 20;287(11):1405-12. PubMed PMID: 11903027.

20 years Julius Center; 1996-2017 29

2002 Karolien DIjkstra Name PhD defense May 28th, 2002 PhD team Visser, Verheij, Lockwood Speciality General Practice Position General Practitioner Department Location Leidsche Rijn Gezondheidscentra Terwijde City Utrecht Country The Netherlands Quote “General Practitioner is the health coach of the future.”

MAIN PAPER Dijkstra K, Funai EF, O’Neill L, Rebarber A, Paidas MJ, Young BK. Change in cervical length after cerclage as a predictor of preterm delivery. Obstet Gynecol. 2000 Sep;96(3):346-50. PubMed PMID: 10960624.

2002 Name Joëlle Erkens PhD defense May 21st, 2002 PhD team Leufkens, Grobbee, Klungel, Stolk Speciality Pharmacoepidemiology Position Deceased June 10th, 2011 Department Location City Country Quote MAIN PAPER Erkens JA, Herings RM, Stolk RP, Spoelstra JA, Grobbee DE, Leufkens HG. Cardiovascular risk factors and diseases precede oral hypoglycaemic therapy in patients with type 2 diabetes mellitus. J Clin Epidemiol. 2002 Apr;55(4):345-9. PubMed PMID: 11927201.

30 20 years Julius Center; 1996-2017

2002 Name Eveline Geubels PhD defense October 29th, 2002 PhD team Grobbee, Vandenbroucke-Grauls Speciality Community-based and health facility-based (HMIS-type) surveillance systems Position Thematic Group leader - Impact Evaluation Department Location Ifakara Health Institute City Ifakara Country Tanzania Quote “...”

MAIN PAPER Geubbels EL, Nagelkerke NJ, Mintjes-De Groot AJ, Vandenbroucke-Grauls CM,Grobbee DE, De Boer AS. Reduced risk of surgical site infections through surveillance in a network. Int J Qual Health Care.

2006 Apr;18(2):127-33. PubMed PMID: 16484315.

2002 Name Olga van der Hel PhD defense December 6th, 2002 PhD team Grobbee, Peeters, Bueno de Mesquita Epidemiology of Cancer Speciality Position Consultant Department Location Netherlands Comprehensive Cancer Organisation (Integraal Kankercentrum Nederland (IKNL)) City Utrecht The Netherlands Country “Ieder grapje heeft een kern van waarheid “ Quote MAIN PAPER van der Hel OL, Peeters PH, Hein DW, Doll MA, Grobbee DE, Kromhout D, Bueno de Mesquita HB. NAT2 slow acetylation and GSTM1 null genotypes may increase postmenopausal breast cancer risk in long-term smoking women. Pharmacogenetics. 2003 Jul;13(7):399407. PubMed PMID: 12835615.

20 years Julius Center; 1996-2017 31

2002 Susan van den Hof Name PhD defense December 6th, 2002 PhD team Grobbee, Conyn-van Spaendonk, de Melker Speciality Epidemiology of Infectious Diseases Position Senior Epidemiologist Department Location KNCV Tuberculosis Foundation.

City The Hague Country The Netherlands Quote “...”

MAIN PAPER van den Hof S, van den Kerkhof JH, ten Ham PB, van Binnendijk RS, Conyn-van Spaendonck MA, van Steenbergen JE. [Measles epidemic in the Netherlands,1999-2000]. Ned Tijdschr Geneeskd.

2001 Dec 29;145(52):2529-33. PubMed PMID: 11793829.

2002 Name Lucienne Hoogwerf PhD defense December 17th, 2002 PhD team Grypdonck, van Dijkum Speciality Nursing Sciences & Management Position Vice Chair Board of Directors Department Location Tragel Foundation (Care for mentally disabled individuals) City Clinge Country The Netherlands Quote “...”

MAIN PAPER Vallenga D, Grypdonck MH, Hoogwerf LJ, Tan FI. Action research: what, why and how? Acta Neurol Belg. 2009 Jun;109(2):81-90.

PubMed PMID: 19681439.

32 20 years Julius Center; 1996-2017

2002 Name Susan Jedeloo PhD defense May 8th, 2002 PhD team Schrijvers, de Witte Speciality Researcher & lecturer Position Owner at Aililio - Kunst van Eigen Kracht; Lecturer Department Location University of Appled Sciences Rotterdam City Rotterdam Country The Netherlands Quote “...”

MAIN PAPER Jedeloo S, De Witte LP, Linssen BA, Schrijvers AJ. Client satisfaction with service delivery of assistive technology for outdoor mobility.

Disabil Rehabil. 2002 Jul 10;24(10):550-7. PubMed PMID: 12171645.

2002 Name Lital Keinan-Boker PhD defense November 12th, 2002 PhD team Grobbee, Peeters Epidemiology of Cancer Speciality Position Associate Professor & Visiting Professor Epidemiology Department Location The Hebrew University of Jerusalem & Trinity College Dublin Haifa & Dublin City Israël & Ireland Country Quote “...”

MAIN PAPER Keinan-Boker L, Bueno De Mesquita HB, Kaaks R, Van Gils CH, Van Noord PA, Rinaldi S, et al. Circulating levels of insulin-like growth factor I, its binding proteins -1,-2, -3, C-peptide and risk of postmenopausal breast cancer. Int J Cancer. 2003 Aug 10;106(1):90-5.

PubMed PMID: 12794762.

20 years Julius Center; 1996-2017 33

2002 Name Wilton van Klei PhD defense April 16th, 2002 PhD team Knape, Grobbee, Moons, Rutten Speciality Anaesthesiology Position Professor of Anaesthesiology, and chair Department Anaesthesiology Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “...”

MAIN PAPER van Waes JA, Nathoe HM, de Graaff JC, Kemperman H, de Borst GJ, Peelen LM, van Klei WA; Cardiac Health After Surgery (CHASE) Investigators. Myocardial injury after noncardiac surgery and its association with short-term mortality. Circulation. 2013 Jun 11;127(23):2264-71.PubMed PMID: 23667270.

2002 Name Laurens Koopman PhD defense February 27th, 2002 PhD team Neijens, Brunekreef Speciality Pediatric Cardiology Position Pediatric Cardiologist Department Cardiology, Children’s Hospital Location Erasmus Medical Center City Rotterdam Country The Netherlands Quote “…”

MAIN PAPER Koopman LP, van Strien RT, Kerkhof M, Wijga A, Smit HA, de Jongste JC, et al. Prevention and Incidence of Asthma and Mite Allergy (PIAMA) Study. Placebo-controlled trial of house dust miteimpermeable mattress covers: effect on symptoms in early childhood. Am J Respir Crit Care Med. 2002 Aug 1;166(3):307-13.

PubMed PMID: 12153962

34 20 years Julius Center; 1996-2017

2002 Name Gea de Meer PhD defense May 27th, 2002 PhD team Brunekreef, Postma, Heederik Speciality Environmental Health Epidemiology Advisor Environment and Health Position Department Location Public Health Service Leeuwarden (GGD) City Leeuwarden Country The Netherlands Quote “...”

MAIN PAPER de Meer G, Janssen NA, Brunekreef B. Early childhood environment related to microbial exposure and the occurrence of atopic disease at school age. Allergy. 2005 May;60(5):619-25. PubMed PMID: 15813806.

2002 Name Paul Nederkoorn PhD defense June 14th, 2002 PhD team Van der Graaf, Hunnik, Mali Speciality Neurology Acute stroke Neurologist Position Department Neurology Location Academic Medical Center - University of Amsterdam City Amsterdam The Netherlands Country Quote “The doctor’s assumption that health is a relative absence of disease is not good enough” DW Winnicott MAIN PAPER Nederkoorn PJ, Mali WP, Eikelboom BC, Elgersma OE, Buskens E, Hunink MG, et al. Preoperative diagnosis of carotid artery stenosis: accuracy of noninvasive testing. Stroke. 2002 Aug;33(8):2003-8.

PubMed PMID: 12154253.

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2002 Name Anath Oren PhD defense November 14th, 2002 PhD team Grobbee, Bots Speciality Pediatric Medicine Position Pediatrician Department Pediatric Medicine Location Kennemer Hospital City Haarlem Country The Netherlands Quote “...”

MAIN PAPER Oren A, Vos LE, Uiterwaal CS, Grobbee DE, Bots ML. Cardiovascular risk factors and increased carotid intima-media thickness in healthy young adults: the Atherosclerosis Risk in Young Adults (ARYA) Study. Arch Intern Med. 2003 Aug 11-25;163(15):1787-92. PubMed PMID: 12912713.

2002 Name Marlies Ossewaarde PhD defense February 8th, 2002 PhD team Grobbee, Bots, van der Schouw Speciality Geriatric Medicine Position Geriatrician Department Internal Medicine Location Hospital Rivierenland City Tiel Country The Netherlands Quote “...”

MAIN PAPER Ossewaarde ME, Bots ML, Verbeek AL, Peeters PH, van der Graaf Y, Grobbee DE, van der Schouw YT. Age at menopause, cause-specific mortality and total life expectancy. Epidemiology. 2005 Jul;16(4):556-62. PubMed PMID: 15951675.

36 20 years Julius Center; 1996-2017

2002 Name Ruud Pijnappel PhD defense May 17th, 2002 PhD team Mali, Holland, Peeters Speciality Radiology Professor of Breast Radiology Position Department Imaging department University Medical Center Utrecht Location City Utrecht Country The Netherlands Quote “...”

MAIN PAPER Pijnappel RM, Peeters PH, van den Donk M, Holland R, Hendriks JH, Deurloo EE, Mali WP. Diagnostic strategies in non-palpable breast lesions. Eur J Cancer. 2002 Mar;38(4):550-5. PubMed PMID: 11872348.

2002 Name Henk Rosendal PhD defense September 24th, 2002 PhD team Schrijvers, van Beekum, de Witte Health Sciences Speciality Lecturer Community Care Position Department Location Hogeschool Rotterdam (Rotterdam University of Applied Sciences) City Rotterdam The Netherlands Country Quote “Alleen ga je sneller, maar samen kom je verder” - Afrikaans gezegde MAIN PAPER Rosendal H, van Beekum WT, Nijhof P, de Witte LP, Schrijvers AJ. Can shared care deliver better outcomes for patients undergoing total hip replacement? A prospective assessment of patient outcomes and associated service use. Int J Integr Care. 2000 Nov 1;1:e10.

PubMed PMID: 16902701.

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2002 Name José Spoelstra PhD defense November 6th, 2002 PhD team Grobbee, Leufkens, Stolk, Klungel Speciality Rehabilitation Medicine Position Resident in Rehabilitation Medicine Department Rehabillitation Location Rehabilitation Hospital Roessingh City Enschede Country The Netherlands Quote “...”

MAIN PAPER Spoelstra JA, Stolk RP, Klungel OH, Erkens JA, Rutten GE, Leufkens HG, Grobbee DE. Initiation of glucose-lowering therapy in Type 2 diabetes mellitus patients in general practice. Diabet Med. 2004 Aug;21(8):896-900. PubMed PMID: 15270794.

2002 Name Rob van Strien PhD defense January 29th 2002 PhD team Brunekreef Speciality Environmental Health Epidemiology Position Environmental Health Specialist Department Environmental Health Location Public Health Service Amsterdam (GGD) City Amsterdam Country The Netherlands Quote “...”

MAIN PAPER Dijkema MB, van Strien RT, van der Zee SC, Mallant SF, Fischer P, Hoek G, et al. Spatial variation in nitrogen dioxide concentrations and cardiopulmonary hospital admissions. Environ Res. 2016 Nov;151:721-727. PubMed PMID: 27644030

38 20 years Julius Center; 1996-2016

2002 Name Francine van Venrooij PhD defense March 1st, 2002 PhD team Erkelens, Stolk, Banga Speciality Internal Medicine Position Internist Department Internal Medicine Albert Schweitzer Hospital Location City Dordrecht Country The Netherlands Quote “...”

MAIN PAPER van Venrooij FV, van de Ree MA, Bots ML, Stolk RP, Huisman MV, Banga JD; DALI Study Group. Aggressive lipid lowering does not improve endothelial function in type 2 diabetes: the Diabetes Atorvastatin Lipid Intervention (DALI) Study: a randomized, doubleblind, placebo-controlled trial. Diabetes Care. 2002 Jul;25(7):1211-6.

PubMed PMID: 12087021.

2002 Name Catherine Weijnen PhD defense February 7th, 2002 Verheij, Hoes, de Wit, Numans PhD team Clinical Epidemiology Speciality Position Associate Director Primary Care Research Julius Clinical & Assistant professor Department Location Julius Clinical Research and clinical epidemiology, Julius Center for Health Sciences and Primary Ccare City Zeist & Utrecht Country The Netherlands Quote “In een maatschappij zonder wachten krijgen gedachten geen kans” MAIN PAPER Weijnen CF, Numans ME, de Wit NJ, Smout AJ, Moons KG, Verheij TJ, Hoes AW. Testing for Helicobacter pylori in dyspeptic patients suspected of peptic ulcer disease in primary care: cross sectional study. BMJ. 2001 Jul 14;323(7304):71-5. PubMed PMID: 11451780.

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Class of

2003

2003 Kristel van Asselt Name PhD defense September 30th, 2003 PhD team Grobbee, Peeters, van der Schouw Speciality General Practice Position General Practitioner & lecturer and Senior Researcher Department General Practice Location Own General Practice & Academic Medical Center – University of Amsterdam Kockengen & Amsterdam City Country The Netherlands Quote “The best way to predict future is to create it“ - A.Lincoln MAIN PAPER van Asselt KM, Kok HS, Putter H, Wijmenga C, Peeters PH, van der Schouw YT,et al. Linkage analysis of extremely discordant and concordant sibling pairs identifies quantitative trait loci influencing variation in human menopausal age. Am J Hum Genet. 2004 Mar;74(3):444-53. PubMed PMID: 14872408

2003 Name Carole Brouwer PhD defense April 15th, 2003 PhD team Grobbee, Maillé, Sanders, Schilder Speciality Pediatric Intensive Care Position Pediatric Intensivist Department Location Leiden University Medical Center City Leiden Country The Netherlands Quote “...”

MAIN PAPER Brouwer CN, Maillé AR, Rovers MM, Veenhoven RH, Grobbee DE, Sanders EA, Schilder AG. Effect of pneumococcal vaccination on quality of life in children with recurrent acute otitis media: a randomized, controlled trial. Pediatrics. 2005 Feb;115(2):273-9. PubMed PMID: 15687432.

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2003 Name Sjoerd Elias PhD defense December 11th, 2003 PhD team Grobbee, Peeters, van Noord Speciality Epidemiology of Cancer Postdoctoral Researcher Position Department Clincial Epidemiology, Julius Center for Health Sciences and Primary Care University Medical Center Utrecht Location City Utrecht The Netherlands Country Quote “Wonder is the beginning of wisdom“ - Socrate MAIN PAPER Elias SG, Peeters PH, Grobbee DE, van Noord PA. Breast cancer risk after caloric restriction during the 1944-1945 Dutch famine. J Natl Cancer Inst. 2004 Apr 7;96(7):539-46. PubMed PMID: 15069116.

2003 Maarten van Gorp Name PhD defense December 9th, 2003 PhD team Van der Graaf, Mali, Bakker Speciality Radiology Position Radiologist Department Radiology and Nuclear Medince Location Rijnstate Hospital City Arnhem Country The Netherlands Quote “...”

MAIN PAPER van Gorp MJ, Steyerberg EW, Van der Graaf Y. Decision guidelines for prophylactic replacement of Björk-Shiley convexo-concave heart valves: impact on clinical practice. Circulation. 2004 May 4;109(17):2092-6. PubMed PMID: 15078796.

44 20 years Julius Center; 1996-2017

2003 Name Thóra Hafsteinsdottir PhD defense March 14th, 2003 PhD team Grypdonck, Kappelle, Algra Speciality Nursing Sciences Position Senior Researcher & Professor of Nursing Department Nursing Science, Julius Center for Health Sciences and Primary Care & Faculty of Nursing Location University Medical Center Utrecht Utrecht & University of Iceland Utrecht & Reykjavik City Country The Netherlands & Iceland Quote “always walk on the bright side of life” MAIN PAPER Hafsteinsdóttir TB, Algra A, Kappelle LJ, Grypdonck MH; Dutch NDT Study Group. Neurodevelopmental treatment after stroke: a comparative study. J Neurol Neurosurg Psychiatry. 2005 Jun;76(6):788-92. PubMed PMID: 15897499.

2003 Name Lidewij Hoorntje PhD defense October 9th, 2003 PhD team Borel Rinkes, Mali, Peeters Speciality Plastic Surgery Position Plastic Reconstructive & Hand Surgeon Department Plastic Surgery Location Martini Hospital City Groningen Country The Netherlands Quote “...”

MAIN PAPER Hoorntje LE, Peeters PH, Mali WP, Borel Rinkes IH. Is stereotactic large-core needle biopsy beneficial prior to surgical treatment in BI-RADS 5 lesions? Breast Cancer Res Treat. 2004 Jul;86(2):165-70.

PubMed PMID: 15319568.

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2003 Name Frederike Jörg PhD defense February 28th, 2003 PhD team Schrijvers, Hox, Boeije Speciality Psychiatry Senior Researcher Position Department University Center Psychiatry University Medical Center Groningen Location City Groningen Country The Netherlands “No health without mental health” Quote MAIN PAPER Bruins J, Pijnenborg GH, van den Heuvel ER, Visser E, Corpeleijn E, Bartels-Velthuis AA, Bruggeman R, Jörg F. Persistent Low Rates of Treatment of Metabolic Risk Factors in People With Psychotic Disorders: A PHAMOUS Study. J Clin Psychiatry. 2017 Apr 11. doi: 10.4088/JCP.16m10831. [Epub ahead of print]

2003 Name Willemijn Klein PhD defense September 16th, 2003 PhD team Mali, van der Graaf Speciality Radiology Pediatric and forensic radiologist Position Department Radiology and Nuclear Medicine Location Radboud University Medical Center & Maastricht University Medical Center City Nijmegen & Maastricht The Netherlands Country “Hebben is hebben; krijgen is de kunst“ Quote MAIN PAPER Klein WM, van der Graaf Y, Seegers J, Moll FL, Mali WP. Long-term cardiovascular morbidity, mortality, and reintervention after endovascular treatment in patients with iliac artery disease: The Dutch Iliac Stent Trial Study. Radiology. 2004 Aug;232(2):491-8.

PubMed PMID: 15286319.

46 20 years Julius Center; 1996-2017

2003 Helen Kok Name PhD defense September 30th, 2003 PhD team Grobbee, Peeters, van der Schouw, Te Velde Speciality Gynaecology Position Gynaecologist Department Obstetrics and Gynaecology Location Alrijne Hospital Leiden & Geboortehuis Leiden University Medical Center City Leiden Country The Netherlands Quote “...”

MAIN PAPER Kok HS, van Asselt KM, van der Schouw YT, van der Tweel I, Peeters PH, Wilson PW, et al. Heart disease risk determines menopausal age rather than the reverse. J Am Coll Cardiol. 2006 May 16;47(10):197683. PubMed PMID: 16697313.

2003 Name Linda Kok PhD defense March 25th, 2003 PhD team Grobbee, van der Schouw Speciality Position Advisor Department Location Dutch Institute for Rational Use of Medicine (Instituut voor Verantwoord Medicijngebruik) City Utrecht Country The Netherlands Quote “...”

MAIN PAPER Kok L, Kreijkamp-Kaspers S, Grobbee DE, Lampe JW, van der Schouw YT. Soy isoflavones, body composition, and physical performance. Maturitas. 2005 Oct 16;52(2):102-10. PubMed PMID: 16186072.

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2003 Name Irene Koomen PhD defense February 21th, 2003 PhD team Grobbee, Roord, van Furth Speciality Pediatrics Medicine Position Pediatrician Department Pediatric Medicine WestfriesGasthuis Location City Hoorn Country The Netherlands Quote ...”

MAIN PAPER Koomen I, Raat H, Jennekens-Schinkel A, Grobbee DE, Roord JJ, van Furth M.Academic and behavioral limitations and health-related quality of life in school-age survivors of bacterial meningitis. Qual Life Res. 2005 Aug;14(6):1563-72. PubMed PMID: 16110936.

2003 Name Andrea ‘t Mannetje PhD defense March 13th, 2003 PhD team Brunekreef, Boffetta, Kromhout Speciality Epidemiology Position Epidemiologist Department Center for Public Health Research Location Massey University Раlmеrstоn Nоrth City Country New Zealand Quote “...”

MAIN PAPER Mannetje A, Eng A, Walls C, Dryson E, Kogevinas M, Brooks C, et al.

Sex ratio of the offspring of New Zealand phenoxy herbicide producers exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Occup Environ Med. 2017 Jan;74(1):24-29. PubMed PMID: 27581706.

48 20 years Julius Center; 1996-2017

2003 Name Berno van Meijel PhD defense June 10th, 2003 Grypdonck, Kahn, van der Gaag PhD team Speciality Nursing Sciences in Psychiatry and Social Medicine Position Professor Department Psychiatry and Social Medicine Location VU University Medical Center Amsterdam City Amsterdam Country The Netherlands Quote “...”

MAIN PAPER Fluttert FA, Van Meijel B, Bjørkly S, Van Leeuwen M, Grypdonck M. The investigation of early warning signs of aggression in forensic patients by means of the ‘Forensic Early Signs of Aggression Inventory’. J Clin Nurs. 2013 Jun;22(11-12):1550-8. PubMed PMID: 23043702.

2003 Name Majon Muller PhD defense November 14th, 2003 PhD team Grobbee, van der Schouw Speciality Geriatric Medicine Position Professor in Geriatric medicine Department Internal Medicine and Elderly Medicine Location VU University Medical Center Amsterdam City Amsterdam Country The Netherlands Quote “...”

MAIN PAPER Muller M, Grobbee DE, Aleman A, Bots M, van der Schouw YT. Cardiovascular disease and cognitive performance in middle-aged and elderly men. Atherosclerosis. 2007 Jan;190(1):143-9. PubMed PMID: 16488420.

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2003 Name Paul Rheeder PhD defense September 15th, 2003 PhD team Grobbee, Stolk Speciality Internal Medicine Position Professor Department Internal Medicine, Steve Biko Academic Hospital, Faculty of Health Sciences University of Pretoria Location City Pretoria South Africa Country Quote “All men dream, but not equally. Those who dream by night in the dusty recesses of their minds, wake in the day to find that it was vanity: but the dreamers of the day are dangerous men, for they may act on their dreams with open eyes, to make them possible.” T. E. Lawrence MAIN PAPER Webb EM, Rheeder P, Roux P. Screening in Primary Care for Diabetic Retinopathy, Maculopathy and Visual Loss in South Africa.

Ophthalmologica. 2016;235(3):141-9. PubMed PMID: 26959502 2003 Name Lisette Schoonhoven PhD defense February 7th, 2003 Grobbee, Buskens PhD team Nursing Sciences Speciality Professor of Nursing Position Department Faculty of Health Sciences University of Southampton Location City Southampton Country United Kingdom Quote “Whatever you decide to do, make sure it makes you happy!”

MAIN PAPER van den Boogaard M, Pickkers P, Slooter AJ, Kuiper MA, Spronk PE, van der Voort PH, et al. Development and validation of PRE-DELIRIC (PREdiction of DELIRium in ICu patients) delirium prediction model for intensive care patients: observational multicentre study. BMJ. 2012 Feb 9;344:e420. PubMed PMID: 22323509.

50 20 years Julius Center; 1996-2017

2003 Aafke Sierksma Name PhD defense November 10th, 2003 PhD team Grobbee, Hendriks Speciality Epidemiology of Beer Consumption Position Director Department Location The Dutch Beer Institute City Wageningen Country The Netherlands Quote “Geniet nooit met mate” - Loesje MAIN PAPER Sierksma A, Patel H, Ouchi N, Kihara S, Funahashi T, Heine RJ, et al.

Effect of moderate alcohol consumption on adiponectin, tumor necrosis factor-alpha, and insulin sensitivity. Diabetes Care. 2004 Jan;27(1):184-9. PubMed PMID: 14693987.

2003 Name Paul Uitewaal PhD defense November 5th, 2003 PhD team Thomas, Hoes, Bruijnzeels Speciality General Practice Position General Practitioner Department Department of Public Health & The Hague’s Public Health Department (GG Haaglanden) Location General Practice de Blauwe Tulp City The Hague Country The Netherlands Quote “…”

MAIN PAPER Uitewaal PJ, Goudswaard AN, Ubink-Veltmaat LJ, Bruijnzeels MA, Hoes AW, Thomas S. Cardiovascular risk factors in Turkish immigrants with type 2 diabetes mellitus: comparison with Dutch patients. Eur J Epidemiol. 2004;19(10):923-9. PubMed PMID: 15575350.

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2003 Name Lydia Vos PhD defense March 15th, 2003 PhD team Grobbee, Uiterwaal Speciality Dermatology / Venereology Position Dermatologist-venereologist Department Dermatology Haaglanden Medical Center Location The Hague City Country The Netherlands “Pluk de dag!“ Quote MAIN PAPER Vos LE, Oren A, Uiterwaal C, Gorissen WH, Grobbee DE, Bots ML. Adolescent blood pressure and blood pressure tracking into young adulthood are related to subclinical atherosclerosis: the Atherosclerosis Risk in Young Adults (ARYA) study. Am J Hypertens. 2003 Jul;16(7):549-55. PubMed PMID: 12850388.

2003 Name Daniël Witte PhD defense May 23rd, 2003 PhD team Grobbee, van der Graaf, Bots Epidemiology of Diabetes Speciality Professor of Diabetes Epidemiology Position Department Public Health, Faculty of Health Location Aarhus University City Aarhus Country Denmark Quote “Experience is simply the name we give our mistakes.” - Oscar Wilde MAIN PAPER Tabák AG, Jokela M, Akbaraly TN, Brunner EJ, Kivimäki M, Witte DR. Trajectories of glycaemia, insulin sensitivity, and insulin secretion before diagnosis of type 2 diabetes: an analysis from the Whitehall II study. Lancet. 2009 Jun 27;373(9682):2215-21. PubMed PMID: 19515410

52 20 years Julius Center; 1996-2017

Class of

2004

2004 Daphne van der A Name PhD defense October 8th, 2004 PhD team Grobbee, Marx, van der Schouw Speciality Project manager Public Health Monitor Position Senior Epidemiologist Department Center for Nutrition, Prevention and Health Services Location National Institute for Public Health and the Environment (RIVM) City Bilthoven Country The Netherlands Quote “If you can’t explain it simply, you don’t understand it well enough “ - Albert Einstein MAIN PAPER van der A DL, Marx JJ, Grobbee DE, Kamphuis MH, Georgiou NA, van Kats-Renaud JH, et al. Non-transferrin-bound iron and risk of coronary heart disease in postmenopausal women. Circulation.

2006 Apr 25;113(16):1942-9. PubMed PMID: 16618820.

2004 Name Jet van den Akker PhD defense September 28th, 2004 PhD team Hoes, Hordijk, Schilder Speciality Ear, Nose, and Throat Medicine Position Ear, Nose, and Throat surgeon Department Ear, Nose, and Throat Medicine Location Meander Medical Center City Amersfoort Country The Netherlands Quote “...”

MAIN PAPER van den Akker EH, Sanders EA, van Staaij BK, Rijkers GT, Rovers MM, Hoes AW, Schilder AG. Long-term effects of pediatric adenotonsillectomy on serum immunoglobulin levels: results of a randomized controlled trial. Ann Allergy Asthma Immunol. 2006 Aug;97(2):251-6. PubMed PMID: 16937760.

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2004 Marie-José Veldman- Ariesen Name PhD defense October 12th, 2004 PhD team Grobbee, Algra Speciality Epidemiology Position Stroke survivor and proud mum Department Location City Country The Netherlands Quote “Don’t worry about tomorrow, He’s got it under control, just trust in the Lord with all of your heart and He will carry you through” MAIN PAPER Ariesen MJ, Claus SP, Rinkel GJE, Algra A. Risk factors for intracerebral hemorrhage in the general population: a systematic review.

Stroke 2003;34:2060-5.

2004 Name Bert-Jan de Boer PhD defense May 25th, 2004 PhD team Verheij, Lycklama à Nijeholt, Bots, Moors Speciality General Practice Position General Practitioner, interest in sexology and men ; Lecturer Residents in General Practice Department De Boer MannenGezondheid en Zorg & General Practice , Julius Center for Health Science and Primary Care Location University Medical Center Utrecht City Bilthoven & Utrecht Country The Netherlands Quote “Men are only human” MAIN PAPER de Boer BJ, Bots ML, Lycklama a Nijeholt AA, Moors JP, Pieters HM, Verheij TJ. Erectile dysfunction in primary care: prevalence and patient characteristics. The ENIGMA study. Int J Impot Res. 2004 Aug;16(4):358-64. PubMed PMID: 14961062.

58 20 years Julius Center; 1996-2017

2004 Marie Louise de Bruin Name PhD defense December 1st, 2004 PhD team Leufkens, Hoes Speciality Pharmaceutical Sciences Position Professor in Regulatory Science & Director of the Copenhagen Centre for Regulatory Science Department Faculty of Health and Medical Sciences & Department of Pharmacy Location University of Copenhagen City Copenhagen Country Denmark Quote “...”

MAIN PAPER De Bruin ML, Langendijk PN, Koopmans RP, Wilde AA, Leufkens HG, Hoes AW. In-hospital cardiac arrest is associated with use of non-antiarrhythmic QTc-prolonging drugs. Br J Clin Pharmacol. 2007 Feb;63(2):216-23. PubMed PMID: 16869820

2004 Name Wijnia Derks PhD defense October 25th, 2004 PhD team Winnubst, Hordijk, de Leeuw Speciality Ear, Nose and Throat Medicine Position Ear, Nose and Throat Surgeon Department Ear, Nose and Throat Medicine Location Onze Lieve Vrouwen Gasthuis City Amsterdam Country The Netherlands Quote “...”

MAIN PAPER Derks W, de Leeuw RJ, Hordijk GJ, Winnubst JA. Quality of life in elderly patients with head and neck cancer one year after diagnosis.

Head Neck. 2004 Dec;26(12):1045-52. PubMed PMID: 15459917.

20 years Julius Center; 1996-2017 59

2004 Name Lex Goudswaard PhD defense May 25th, 2004 PhD team Rutten, Stolk, de Valk Speciality General Practice Position General Practitioner Department Location Own general practice City Houten Country The Netherlands Quote “Trust the process“ MAIN PAPER Goudswaard AN, Stolk RP, Zuithoff P, de Valk HW, Rutten GE. Starting insulin in type 2 diabetes: continue oral hypoglycemic agents?

A randomized trial in primary care. J Fam Pract. 2004 May;53(5):393-9. PubMed PMID: 15125825.

2004 Name Guus de Hollander PhD defense May 13th, 2006 PhD team Brunekreef Speciality Environmental Health Epidemiology Position Senior Researcher Department Spatial Planning and Quality of the Local Environment Location PBL Netherlands Environmental Assessment Agency City The Hague Country The Netherlands Quote “...”

MAIN PAPER van Genugten ML, Hoogenveen RT, Mulder I, Smit HA, Jansen J, de Hollander AE. Future burden and costs of smoking-related disease in the Netherlands: a dynamic modeling approach. Value Health.

2003 Jul-Aug;6(4):494-9. PubMed PMID: 12859591.

60 20 years Julius Center; 1996-2017

2004 Name Mariëtte Hooiveld PhD defense January 14th, 2004 PhD team Heederick, Kromhout, Speciality Primary Care Health Care Services Position Senior Researcher Department Projectleider NIVEL zorgregistraties eerste lijn - Surveillance en senior onderzoeker epidemiologie van rampen, arbeid en milieu Location Netherlands Institute for Health Services Research (NIVEL) City Utrecht Country The Netherlands Quote “...”

MAIN PAPER Hooiveld M, Smit LA, van der Sman-de Beer F, Wouters IM, van Dijk CE, Spreeuwenberg P, et al. Doctor-diagnosed health problems in a region with a high density of concentrated animal feeding operations: a cross-sectional study. Environ Health. 2016 Feb 17;15:24.

PubMed PMID: 26888643.

2004 Name Jeroen Koerselman PhD defense November 17th, 2004 PhD team Grobbee, van der Graaf, de Jaegere Speciality Occupational medicine Position Physician Department A-REA, Zeist Location City Zeist Country The Netherlands Quote “carpe diem “ MAIN PAPER Koerselman J, van der Graaf Y, de Jaegere PP, Grobbee DE. Coronary collaterals: an important and underexposed aspect of coronary artery disease. Circulation. 2003 May 20;107(19):2507-11. PubMed PMID: 12756191.

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2004 Sanne Kreijkamp-Kaspers Name PhD defense April 20th, 2004 PhD team Grobbee, van der Schouw Speciality Epidemiology Position Senior Lecturer Department Primary Care Clinical Unit, Faculty of Medicine Location University of Queensland City Brisbane Country Australia Quote “...”

MAIN PAPER Kreijkamp-Kaspers S, McGuire T, Bedford S, Loadsman P, Pirotta M, Moses G, van Driel ML. Your questions about complementary medicines answered: fish oil. Aust Fam Physician. 2015 Jul;44(7):469-70. PubMed PMID: 26590490.

2004 Name Marjan Muis PhD defense June 4th, 2004 PhD team Grobbee, Hoekstra, Stolk, Muis Speciality Endocrinology & Diabetology Position Internist-Endocrinologist Department Internal Medicine Location St Jansdal Hospital & City Harderwijk Country The Netherlands Quote “...”

MAIN PAPER Muis MJ, Bots ML, Grobbee DE, Stolk RP. Insulin treatment and cardiovascular disease; friend or foe? A point of view. Diabet Med. 2005 Feb;22(2):118-26. PubMed PMID: 15660727.

62 20 years Julius Center; 1996-2017

2004 Name Charlotte Onland-Moret PhD defense April 15th, 2004 PhD team Grobbee, van der Schouw, Peeters Speciality Clinical Epidemiology Assistant Professor Position Department Clinical Epidemiology, Julius Center for Health Sciences and Primary Care University Medical Center Utrecht Location City Utrecht The Netherlands Country Quote “...”

MAIN PAPER de Kat AC, Dam V, Onland-Moret NC, Eijkemans MJ, Broekmans FJ, van der Schouw YT. Unraveling the associations of age and menopause with cardiovascular risk factors in a large population-based study. BMC Med. 2017 Jan 4;15(1):2. PubMed PMID: 28049531.

2004 Hendrik Nathoe Name PhD defense June 8th, 2004 PhD team Grobbee, Plokker, de Jaegere, Buskens Speciality Cardiology Position Cardiologist Department Cardiology, Divison Heart & Lungs University Medical Center Utrecht Location City Utrecht Country The Netherlands Quote “We should focus more on clincical relevance than on the number of publications.“ MAIN PAPER Nathoe HM, van Dijk D, Jansen EW, Suyker WJ, Diephuis JC, van Boven WJ, et al. A comparison of on-pump and off-pump coronary bypass surgery in low-risk patients. N Engl J Med. 2003 Jan 30;348(5):394-402. PubMed PMID: 12556542

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2004 Marieke Ostendorf Name PhD defense December 8th, 2004 PhD team Verbout, Schrijvers, Dhert Speciality Orthopedics Position Orthopedic Surgeon Department Orthopedics Location Sint Maartenskliniek City Woerden Country The Netherlands Quote “...”

MAIN PAPER Ostendorf M, van Stel HF, Buskens E, Schrijvers AJ, Marting LN, Verbout AJ, Dhert WJ. Patient-reported outcome in total hip replacement. A comparison of five instruments of health status. J Bone Joint Surg Br. 2004 Aug;86(6):801-8. PubMed PMID: 15330018.

2004 Name Lützen Portengen PhD defense September 28th, 2004 PhD team Heederik, Doekes Speciality Environmental Health Epidemiology Position Assistant Professor Department Environmental Epidemiology, Institute for Risk Assessment Sciences Location Utrecht University City Utrecht Country The Netherlands Quote “...”

MAIN PAPER Lenters V, Portengen L, Smit LA, Jönsson BA, Giwercman A, Rylander L, et al. Phthalates, perfluoroalkyl acids, metals and organochlorines and reproductive function: a multipollutant assessment in Greenlandic, Polish and Ukrainian men. Occup Environ Med. 2015 Jun;72(6):385-93. PubMed PMID: 25209848.

64 20 years Julius Center; 1996-2017

2004 Name Brigitta van Staaij PhD defense October 26th, 2004 PhD team Hoes, Schilder Speciality General Practice Position GP in Amersfoort and committee member of HCE (Huisartsen Coöperatie Eemland) Department Location General Practice Kattenbroek City Amersfoort The Netherlands Country Quote “...”

MAIN PAPER van Staaij BK, van den Akker EH, van der Heijden GJ, Schilder AG, Hoes AW. Adenotonsillectomy for upper respiratory infections: evidence based? Arch Dis Child. 2005 Jan;90(1):19-25. PubMed PMID: 15613505.

2004 Name Monique Stofmeel PhD defense June 1st, 2004 PhD team Van Hemel, Grobbee Speciality Cardiology Position Cardiologist Department Cardiology Location St. Antonius Hospital City Nieuwegein Country The Netherlands Quote “...”

MAIN PAPER Stofmeel MA, van Stel HF, van Hemel NM, Grobbee DE. The relevance of health related quality of life in paced patients. Int J Cardiol.

2005 Jul 20;102(3):377-82. PubMed PMID: 16004880.

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2004 Name Ingeborg van der Tweel PhD defense March 2nd, 2004 PhD team Grobbee, Stijen Speciality Biostatistics Position Biostatistician (retired) Department Biostatistics, Julius Center for Health Sciences and Primary Care Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “The whole of life is sequential, for our future actions are conditioned to some extent by our past experience.“ MAIN PAPER van der Tweel I, Bollen C. Sequential meta-analysis: an efficient decision-making tool. Clin Trials. 2010 Apr;7(2):136-46. PubMed PMID: 20338906.

2004 Name Jeanine Verbunt PhD defense January 16th, 2004 PhD team Knottnerus, van der Heijden, Vlaeyen Speciality Rehabilitation Medicine Position Professor in rehabilitation medicine Department Rehabilitation Medicine Location Maastricht University Medical Center & Adelante City Maastricht Country The Netherlands Quote “...”

MAIN PAPER Verbunt JA, Seelen HA, Vlaeyen JW, van de Heijden GJ, Heuts PH, Pons K, Knottnerus JA. Disuse and deconditioning in chronic low back pain: concepts and hypotheses on contributing mechanisms.

Eur J Pain. 2003;7(1):9-21. PubMed PMID: 12527313.

66 20 years Julius Center; 1996-2017

2004 Name Ineke Welschen PhD defense April 20th, 2004 PhD team Verheij, Hoes, Kuyvenhoven Speciality Health Care Position Staff member Ketenzorg GHOR Midden West Brabant Department Location Geneeskundige Hulpverleningsorganisatie in de regio (GHOR) Midden- en West-Brabant (MWB) City Breda The Netherlands Country Quote “...”

MAIN PAPER Welschen I, Kuyvenhoven MM, Hoes AW, Verheij TJ. Effectiveness of a multiple intervention to reduce antibiotic prescribing for respiratory tract symptoms in primary care: randomised controlled trial.

BMJ. 2004 Aug 21;329(7463):431. PubMed PMID: 15297305.

2004 Name Berendina van Wendel – de Joode PhD defense October 28th, 2004 Heederik, Kromhout, van Heumen PhD team Environmental Health Epidemiology Speciality Senoir Researcher Position Department Central American Institute for Studies on Toxic Substances (IRET) Universidad Nacional Location City Heredia Costa Rica Country Quote “...”

MAIN PAPER van Wendel de Joode B, Mora AM, Lindh CH, Hernández-Bonilla D, Córdoba L, Wesseling C, Hoppin JA, Mergler D. Pesticide exposure and neurodevelopment in children aged 6-9 years from Talamanca, Costa Rica. Cortex. 2016 Dec;85:137-150. PubMed PMID: 27773359

20 years Julius Center; 1996-2017 67

Class of

2005

2005 Name Annemieke Akkerman PhD defense November 1st, 2005 PhD team Verheij, Kuyvenhoven, van der Wouden Speciality Health Care Position Lecturer & Researcher Department Health Care Academy Location Reformed University of Applied Sciences (Hogeschool VIAA) City Zwolle Country The Netherlands Quote “The bigger, the better!”

MAIN PAPER Ross L, Giske T, van Leeuwen R, Baldacchino D, McSherry W, Narayanasamy A, Jarvis P, Schep-Akkerman A. Factors contributing to student nurses’/midwives’ perceived competency in spiritual care.

Nurse Educ Today. 2016 Jan;36:445-51. PubMed PMID: 26541988.

2005 Name Femke Atsma PhD defense December 2nd, 2005 PhD team Grobbee, van der Schouw, Bartelink Speciality Epidemiology Position Senior Researcher Department Scientific Institute for Quality of Healthcare Location Radboud University Medical Center City Nijmegen Country The Netherlands Quote “...”

MAIN PAPER Atsma F, Veldhuizen I, de Kort W, van Kraaij M, Pasker-de Jong P, Deinum J.Hemoglobin level is positively associated with blood pressure in a large cohort of healthy individuals. Hypertension.

2012 Oct;60(4):936-41. PubMed PMID: 22949533.

20 years Julius Center; 1996-2017 71

2005 Gert Bergman Name PhD defense January 11th, 2005 PhD team Meyboom-de Jong, Posteman, Winters, van der Heijden Speciality Oucomes and Health Economics Position Medical Affairs Advisor Department Roche Diabetes Care Location Roche Netherlands City Almere Stad Country The Netherlands Quote “...”

MAIN PAPER Bergman GJ, Winter JC, van Tulder MW, Meyboom-de Jong B, Postema K, van der Heijden GJ. Manipulative therapy in addition to usual medical care accelerates recovery of shoulder complaints at higher costs: economic outcomes of a randomized trial. BMC Musculoskelet Disord. 2010 Sep 6;11:200. PubMed PMID: 20819223

2005 Name PhD defense PhD team Speciality Position Department Location City Country Quote

Corné Biesheuvel April 27th, 2005 Grobbee, Moons Deceased March 5th, 2012

MAIN PAPER Biesheuvel CJ, Vergouwe Y, Oudega R, Hoes AW, Grobbee DE, Moons KG. Advantages of the nested case-control design in diagnostic research. BMC Med Res Methodol.2008 Jul 21;8:48. PubMed PMID: 18644127;

72 20 years Julius Center; 1996-2017

2005 Name Taco Bijlsma PhD defense September 30th, 2005 PhD team Van der Werken, van der Graaf Speciality Surgery Position Surgeon, with emphasis on children and trauma Department Surgery Noordwest Ziekenhuisgroep Location Alkmaar - Den Helder - Heerhugowaard City Country The Netherlands Quote “...”

MAIN PAPER Postma IL, Oner FC, Bijlsma TS, Heetveld MJ, Goslings JC, Bloemers FW. Spinal injuries in an airplane crash: a description of incidence, morphology, and injury mechanism. Spine (Phila Pa 1976). 2015 Apr 15;40(8):530-6. PubMed PMID: 25868093.

2005 Name Martin Bootsma PhD defense May 23rd, 2005 PhD team Diekman, Bonten Epidemiology of Infectious Diseases Speciality Position Mathematical modeling of infectious disease dynamics Department Institute of Mathematics Utrecht University Location City Utrecht The Netherlands Country Quote “...”

MAIN PAPER Haverkate MR, Platteel TN, Fluit AC, Cohen Stuart JW, Leverstein-van Hall MA, Thijsen SF, et al. Quantifying within-household transmission of extended-spectrum β-lactamase-producing bacteria. Clin Microbiol Infect. 2017 Jan;23(1):46.e1-46.e7. PubMed PMID: 27596534.

20 years Julius Center; 1996-2017 73

2005 Xavier Brouha Name PhD defense November 14th, 2005 PhD team Winnubust, Hordijk, de Leeuw Speciality Ear, Nose, and Throat Medicine Position Ear, Nose, and Throat physician Department Otorhinolaryngology Location Admiraal de Ruyter Hospital City Goes Country The Netherlands Quote “...”

MAIN PAPER Brouha XD, Tromp DM, Koole R, Hordijk GJ, Winnubst JA, de Leeuw JR. Professional delay in head and neck cancer patients: analysis of the diagnostic pathway. Oral Oncol. 2007 Jul;43(6):551-6. PubMed PMID: 17005438.

2005 Name Jessica Brussee PhD defense November 25th, 2005 PhD team Brunekreef, de Jongste, Smit Speciality Public Health Position Epidemiological researcher Department Epidemiology and Health Promotion Location Public Health Service Haaglanden City The Hague Country The Netherlands Quote “Laughter is the shortest distance between two people “- Victor Borge MAIN PAPER Brussee JE, Smit HA, Koopman LP, Wijga AH, Kerkhof M, Corver K, et al. Interrupter resistance and wheezing phenotypes at 4 years of age. Am J Respir Crit Care Med. 2004 Jan 15;169(2):209-13. PubMed PMID: 14597483.

74 20 years Julius Center; 1996-2017

2005 Name Olaf Cremer PhD defense October 5th, 2005 PhD team Kalkman, Moons, Van Dijk Speciality Intensive Care Medicine Position Anaesthesiologist Department Anaesthesiology and Intensive Care University Medical Center Utrecht Location City Utrecht Country The Netherlands Quote “...”

MAIN PAPER Cremer OL, Moons KG, van Dijk GW, van Balen P, Kalkman CJ. Prognosis following severe head injury: Development and validation of a model for prediction of death, disability, and functional recovery. J Trauma. 2006 Dec;61(6):1484-91. PubMed PMID: 16983303.

2005 Name Joke Dijk PhD defense March 15th, 2005 PhD team Van der Graaf, Grobbee, Bots Speciality Neurology Position Neurologist Department Neurology Location Academic Medical Center - University of Amsterdam City Amsterdam The Netherlands Country Quote “...”

MAIN PAPER Dijk JM, Algra A, van der Graaf Y, Grobbee DE, Bots ML; SMART study group. Carotid stiffness and the risk of new vascular events in patients with manifest cardiovascular disease. The SMART study.

Eur Heart J. 2005 Jun;26(12):1213-20. PubMed PMID: 15824075.

20 years Julius Center; 1996-2017 75

2005 Name Karin van Dijk PhD defense April 26th, 2005 PhD team Grobbee, van der Bom, van den Berg Speciality Clinical Microbiology Position Head of the Department of Bacteriology, Tuberculosis and Mycology Department Medical Microbiology and Infection Control Location VU University Medical Center Amsterdam City Amsterdam Country The Netherlands Quote “Logic will get you from A to Z; imagination will get you everywhere.” - Albert Einstein MAIN PAPER van Dijk K, Voets GM, Scharringa J, Voskuil S, Fluit AC, Rottier WC, et al. A disc diffusion assay for detection of class A, B and OXA-48 carbapenemases in Enterobacteriaceae using phenyl boronic acid, dipicolinic acid and temocillin. Clin Microbiol Infect. 2014 Apr;20(4):345-9. PubMed PMID: 23927659.

2005 Name Ayten Elvan-Taspinar PhD defense September 8th, 2005 PhD team Bruinse, Koomans, Franx, Bots Speciality Gynaecology/Perinatology Position Perinatologist Department Perinatology Location University Medical Center Groningen City Groningen Country The Netherlands Quote “So many…haha” MAIN PAPER Elvan-Taşpinar A, Bots ML, Franx A, Bruinse HW, Engelbert RH. Stiffness of the arterial wall, joints and skin in women with a history of pre-eclampsia. J Hypertens. 2005 Jan;23(1):147-51. PubMed PMID: 15643137.

76 20 years Julius Center; 1996-2017

2005 Name Mariëlla Giovannangelo PhD defense September 22nd, 2003 PhD team Brunekreef, Hoek Speciality Biomedical Science, emphasis on molecular diagnostics Position Project Manager Molecular Diagnostics Department Location Diatranz Otsuka Limited City Auckland Country New Zealand Quote “...”

MAIN PAPER Giovannangelo M, Gehring U, Nordling E, Oldenwening M, Terpstra G, Bellander T, Hoek G, Heinrich J, Brunekreef B. Determinants of house dust endotoxin in three European countries - the AIRALLERG study. Indoor Air. 2007 Feb;17(1):70-9. PubMed PMID: 17257154.

2005 Name Jeroen de Hartog PhD defense September 27th, 2005 PhD team Brunekreef, Hoek Speciality Teaching Position Teacher Biology Department Location Highschool Veluws College City Apeldoorn Country The Netherlands Quote “...”

MAIN PAPER Boogaard H, Fischer PH, Janssen NA, Kos GP, Weijers EP, Cassee FR, et al. Respiratory effects of a reduction in outdoor air pollution concentrations. Epidemiology. 2013 Sep;24(5):753-61. PubMed PMID: 23873073.

20 years Julius Center; 1996-2017 77

2005 Name Helen Kamphuis PhD defense January 11th, 2005 PhD team Winnubst, Hauer, de Leeuw Speciality Lecturer in methodology Lecturer and Researcher Position Department Location Hanzehogeschool Groningen / Hanze University of Applied Sciences Groningen City Groningen The Netherlands Country Quote “...”

MAIN PAPER Kamphuis HC, de Leeuw JR, Derksen R, Hauer RN, Winnubst JA. Implantable cardioverter defibrillator recipients: quality of life in recipients with and without ICD shock delivery: a prospective study.

Europace. 2003 Oct;5(4):381-9. PubMed PMID: 14753636.

2005 Name Dineke Koek PhD defense November 11th, 2005 PhD team Grobbee, Bots Geriatric Medicine Speciality Geriatrician, Epidemiologist Position Department Geriatric medicine Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “Register-based research is a valuable gift given by the people when used for the people!“ MAIN PAPER Koek HL, Kardaun JW, Gevers E, de Bruin A, Reitsma JB, Grobbee DE, Bots ML. Acute myocardial infarction incidence and hospital mortality: routinely collected national data versus linkage of national registers. Eur J Epidemiol. 2007;22(11):755-62. PubMed PMID: 17828438.

78 20 years Julius Center; 1996-2017

2005 Name Marjolein van der Kolk-Kousemaker PhD defense March 8th, 2005 PhD team Schrijvers, Duijnstee, van Raats Speciality Position We were inable to obtain information through internet and/or personal contact Department Location City Country Quote MAIN PAPER

2005 Name Yvette Konijenberg PhD defense April 1st, 2005 PhD team Kimpen, Buitelaar, Graeff-Meeder, Uiterwaal Speciality Pediatrics - Nephrology Position Pediatrician-Nephrologist Department Location St Jansdal Hospital City Harderwijk Country The Netherlands Quote “...�

MAIN PAPER Knook LM, Lijmer JG, Konijnenberg AY, Hordijk PM, van Engeland H. Quality of life and academic functioning 6 years after Pediatric referral for chronic pain. Acta Paediatr. 2012 Sep;101(9):957-63.

PubMed PMID: 22734701

20 years Julius Center; 1996-2017 79

2005 Ton Kuijpers Name PhD defense October 14th, 2005 PhD team Bouter, van der Windt, van der Heijden Speciality Methodology of Guidelines Position Senior scientific staff Department Dutch College of General Practitioners Location City Utrecht Country The Netherlands Quote “That rug really tied the room together.” – Walter Sobchak MAIN PAPER Kuijpers T, van der Windt DA, Boeke AJ, Twisk JW, Vergouwe Y, Bouter LM, van der Heijden GJ. Clinical prediction rules for the prognosis of shoulder pain in general practice. Pain. 2006 Feb;120(3):276-85. PubMed PMID: 16426760.

2005 Name Anneke Kwee PhD defense October 11th, 2005 PhD team Bruinse, Visser, Bots Speciality Gynaecology Position Gynaecologist & Chair Dutch Research consortium Obstetrics and Gynaecology Department Obstetrics and Gynaecology Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “Wei wu wei (niets doen is ook wat doen)” MAIN PAPER Evers AC, Brouwers HA, Hukkelhoven CW, Nikkels PG, Boon J, van Egmond-Linden A, Hillegersberg J, et al. Perinatal mortality and severe morbidity in low and high risk term pregnancies in the Netherlands: prospective cohort study. BMJ. 2010 Nov 2;341:c5639.

PubMed PMID: 21045050.

80 20 years Julius Center; 1996-2017

2005 Wim Opstelten Name PhD defense October 11th, 2005 PhD team Verheij, Kalkman, Moons, van Essen Speciality General Practice Position General Practitioner & Senior Researcher Department Location Own practice Opstelten/Scholten & Dutch College of General Practitioners City Amersfoort & Utrecht Country The Netherlands Quote “...”

MAIN PAPER van Wijck AJ, Opstelten W, Moons KG, van Essen GA, Stolker RJ, Kalkman CJ, et al. The PINE study of epidural steroids and local anaesthetics to prevent postherpetic neuralgia: a randomised controlled trial. Lancet. 2006 Jan 21;367(9506):219-24. PubMed PMID: 16427490.

2005 Name Ruud Oudega PhD defense September 30th, 2005 PhD team Hoes, Moons Speciality General Practice Position General Practitioner Department General Practice, Julius Center for Health Sciences and Primary Care Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “...”

MAIN PAPER Oudega R, Hoes AW, Moons KG. The Wells rule does not adequately rule out deep venous thrombosis in primary care patients. Ann Intern Med. 2005 Jul 19;143(2):100-7. PubMed PMID: 16027451.

20 years Julius Center; 1996-2017 81

2005 Name Monique Prinssen PhD defense September 9th, 2005 PhD team Blankensteijn, Grobbee, Buskens Speciality General Practice Position General Practitioner Department Location Health Center Oog en Al City Utrecht Country The Netherlands Quote “...”

MAIN PAPER Prinssen M, Verhoeven EL, Buth J, Cuypers PW, van Sambeek MR, Balm R, et al.Dutch Randomized Endovascular Aneurysm Management (DREAM)Trial Group.. A randomized trial comparing conventional and endovascular repair of abdominal aortic aneurysms. N Engl J Med. 2004 Oct 14;351(16):1607-18. PubMed PMID: 15483279.

Deinstitutionalisation of mental health care in the Netherlands from 1993 - 2004.

Dick P. Ravelli.

2005 Name Dick Ravelli PhD defense March 4th, 2005 PhD team Schrijvers, van Engeland Speciality Psychiatry Position Director AltaConsult & Medical Director Max Ernst GGZ Department Location AltaConsult & Max Ernst GGZ (Mental Health and Addiction Care ) City Arnhem Country The Netherlands Quote “...”

MAIN PAPER Ravelli DP, Buwalda VJ, Slooff CJ, Schrijvers AJ, van Engeland H. Do integrated mental healthcare organisations facilitate process quality in the treatment of people with schizophrenia and related psychoses? Int J Integr Care. 2003;3:e17. PubMed PMID: 16896377.

82 20 years Julius Center; 1996-2017

2005 Name Sabina Rinaldi PhD defense December 5th, 2005 PhD team Grobbeem Peeters, Kaaks Speciality Epidemiology of Cancer Position Scientist Department Biomarker group Location International Organisation of Research on cancer (IARC) City Lyon Country France Quote “...”

MAIN PAPER Rinaldi S, Plummer M, Biessy C, Castellsagué X, Overvad K, Krüger Kjær S, et al. Endogenous sex steroids and risk of cervical carcinoma: results from the EPIC study. Cancer Epidemiol Biomarkers Prev. 2011 Dec;20(12):2532-40. PubMed PMID: 21994406.

2005 Name Frans Rutten PhD defense October 10th, 2005 PhD team Hoes, Grobbee, Lammers Speciality General Practice Position General Practitioner & Associate Professor of General Practice Department General Practice, Julius Center for Health Sciences and Primary Care Location University Medical Center Utrecht City Rhenen & Utrecht Country The Netherlands Quote “...”

MAIN PAPER Rutten FH, Güder G. The role of beta-blockers in outcomes of patients hospitalized for heart failure and chronic obstructive pulmonary disease. Eur J Heart Fail. 2016 Jul;18(7):849-50. PubMed PMID: 27292415.

20 years Julius Center; 1996-2017 83

2005 Name Els De Schryver PhD defense March 11th, 2005 PhD team Algra, Van Gijn Speciality Neurology Position Neurologist Department Neurology Alrijne Hospital Location City Leiderdorp Country The Netherlands Quote “Be the change that you wish to see in the world” - Ghandi MAIN PAPER De Schryver EL, Algra A, Kappelle LJ, van Gijn J, Koudstaal PJ. Vitamin K antagonists versus antiplatelet therapy after transient ischaemic attack or minor ischaemic stroke of presumed arterial origin. Cochrane Database Syst Rev. 2012 Sep 12;(9):CD001342.

PubMed PMID: 22972051.

2005 Name Stefan Störk PhD defense November 18th, 2005 Grobbee, Angermann, Bots, Von Schacky PhD team Cardiology – Epidemiology Speciality Professor of Cardiology, Director Position Department Comprehensive Heart Failure Center Universität Klinikum Würzburg Location University Hospital Würzburg City Country Germany Quote “All change is not growth, as all movement is not forward”- Ellen Glasgow MAIN PAPER Störk S, van den Beld AW, von Schacky C, Angermann CE, Lamberts SW, Grobbee DE, Bots ML. Carotid artery plaque burden, stiffness, and mortality risk in elderly men: a prospective, population-based cohort study. Circulation. 2004 Jul 20;110(3):344-8. PubMed PMID: 15238459.

84 20 years Julius Center; 1996-2016

2005 Marijke van Trijp Name PhD defense January 21st, 2005 PhD team Grobbee, Bots Speciality Clinical Microbiology Position Clinical microbiologist Department Laboratory for Medical Microbiology Location Groene Hart Hospital City Gouda Country The Netherlands Quote “Dogged does it” MAIN PAPER van Trijp MJ, Bos WJ, van der Schouw YT, Muller M, Grobbee DE, Bots ML. Non-invasively measured structural and functional arterial characteristics and coronary heart disease risk in middle aged and elderly men. Atherosclerosis. 2006 Jul;187(1):110-5. PubMed PMID: 16168418.

2005 Name Debbie Tromp PhD defense June 1st, 2005 PhD team Winnubst, Hordijk, de Leeuw Speciality Psychology Position Lecturer Research and Statistics & Senior Research Fellow in Chair Hospitality, Personality and Behaviour Department Location Hotelschool City The Hague Country The Netherlands Quote “...”

MAIN PAPER Tromp DM, Brouha XD, Hordijk GJ, Winnubst JA, Gebhardt WA, van der Doef MP, De Leeuw JR. Medical care-seeking and health-risk behavior in patients with head and neck cancer: the role of health value, control beliefs and psychological distress. Health Educ Res. 2005 Dec;20(6):665-75. PubMed PMID: 15863624.

20 years Julius Center; 1996-2017 85

2005 Name Iris Weijman PhD defense March 1st, 2005 PhD team Winnubst, Rutten, Schaufeli, Ros Speciality Psychology Position Psychologist Department Location Owner Zee van Tijd & freelance psychologist at OCA Almere City Baarn & Almere The Netherlands Country Quote “The proper function of man is to live, not to exist” - Jack London (1876-1916) MAIN PAPER Weijman I, Ros WJ, Rutten GE, Schaufeli WB, Schabracq MJ, Winnubst JA. Fatigue in employees with diabetes: its relation with work characteristics and diabetes related burden. Occup Environ Med. 2003 Jun;60 Suppl 1:i93-8. PubMed PMID: 12782754.

86 20 years Julius Center; 1996-2016

Class of

2006

2006 Walter Balemans Name PhD defense October 27th, 2006 PhD team Sanders, van der Ent, Rovers Speciality Pediatrics- Pulmonology Position Pediatrician-Pulmonologist Department Pediatric Medicine Location St. Antonius Hospital City Nieuwegein Country The Netherlands Quote “Negeren is vooruit zien” (devies voor jonge ouders die moeten opvoeden) MAIN PAPER Balemans WA, van der Ent CK, Schilder AG, Sanders EA, Zielhuis GA, Rovers MM. Prediction of asthma in young adults using childhood characteristics: Development of a prediction rule. J Clin Epidemiol.

2006 Nov;59(11):1207-12. PubMed PMID: 17027432.

2006 Name Jan Paul van den Berg PhD defense January 23rd, 2006 PhD team Van den Berg, Lindeman, Kalmijn Speciality Rehabilitation Medicine Position Consultant in Rehabilitation Medicine Department Location Centra voor Integrale Revalidatie en Arbeidsactivering Nederland (CIRAN) City Venlo Country The Netherlands Quote “...”

MAIN PAPER Van den Berg JP, Kalmijn S, Lindeman E, Veldink JH, de Visser M, Van der Graaff MM, Wokke JH, Van den Berg LH. Multidisciplinary ALS care improves quality of life in patients with ALS. Neurology. 2005 Oct 25;65(8):1264-7. PubMed PMID: 16247055.

20 years Julius Center; 1996-2017 91

2006 Name Casper Bollen PhD defense June 26th, 2006 PhD team van Vugt, Uiterwaal Speciality Pediatric Medicine Position Pediatrician-Intensivist Department Intensive Care University Medical Center Utrecht Location City Utrecht Country The Netherlands Quote “...�

MAIN PAPER Bollen CW, Uiterwaal CS, van Vught AJ. Meta-regression analysis of high-frequency ventilation vs conventional ventilation in infant respiratory distress syndrome. Intensive Care Med. 2007 Apr;33(4):680-8. PubMed PMID: 17323050.

2006 Name Jolanda van den Bosch PhD defense June 7th, 2006 PhD team Kalkman, Moons, van Klei, Vergouwe Speciality Position We were inable to obtain information through internet and/or personal contact Department Location City Country Quote MAIN PAPER van den Bosch JE, Bonsel GJ, Moons KG, Kalkman CJ. Effect of postoperative experiences on willingness to pay to avoid postoperative pain, nausea, and vomiting. Anesthesiology. 2006 May;104(5):1033-9. PubMed PMID: 16645456.

92 20 years Julius Center; 1996-2017

2006 Dan Cohen Name PhD defense February 16th 2006 PhD team Grobbee, Stolk, Gispen-de Wied Speciality Psychiatry Position Psychiatrist Department Flexible Assertive Community Treatment team Location Mental Health and Addiction Care (GGZ) - Noord Holland Noord City Heerhugowaard Country The Netherlands Quote “...”

MAIN PAPER Cohen D, Stolk RP, Grobbee DE, Gispen-de Wied CC. Hyperglycemia and diabetes in patients with schizophrenia or schizoaffective disorders. Diabetes Care. 2006 Apr;29(4):786-91. PubMed PMID: 16567816.

2006 Name Huug van Duijn PhD defense May 23rd, 2006 PhD team Verheij, Kuyvenhoven Speciality General Practice Position General Practitioner, with interest in cardiovascular disease Department Location Own General Practice City Katwijk Country The Netherlands Quote “Writing a paper is like chiseling a sculpture” MAIN PAPER van Duijn HJ, Kuyvenhoven MM, Schellevis FG, Verheij TJ. Determinants of prescribing of second-choice antibiotics for upper and lower respiratory tract episodes in Dutch general practice.

J Antimicrob Chemother. 2005 Aug;56(2):420-2. PubMed PMID: 15961433.

20 years Julius Center; 1996-2017 93

2006 Name Franzel van Duijnhoven PhD defense January 31rd, 2006 PhD team Grobbee, Peeters, van Gils Speciality Epidemiology of Cancer Assistant Professor Position Department Division of Human Nutrition Wageningen University Location City Wageningen Country The Netherlands Quote “If ‘ifs’ and ‘buts’ were candy and nuts, we’d all have a Merry Christmas“ MAIN PAPER van Duijnhoven FJ, Bueno-De-Mesquita HB, Ferrari P, et al. Fruit,vegetables, and colorectal cancer risk: the European Prospective Investigation into Cancer and Nutrition. Am J Clin Nutr. 2009 May;89(5):1441-52. PubMed PMID: 19339391.

2006 Name Jeroen Geijer PhD defense May 11th, 2006 PhD team Verheij, Hoes, Sachs General Practice Speciality General Practitioner Position Department Location General Practice Ondiep City Utrecht Country The Netherlands Quote “...”

MAIN PAPER Geijer RM, Sachs AP, Verheij TJ, Lammers JW, Salomé PL, Hoes AW. Are patient characteristics helpful in recognizing mild COPD (GOLD I) in daily practice? Scand J Prim Health Care. 2006 Dec;24(4):23742. PubMed PMID: 17118864.

94 20 years Julius Center; 1996-2017

2006 Name Jacques Gereats PhD defense March 9th, 2006 PhD team Van den Heuvel, DInant, Goossens, van der Heijden Speciality Physiotherapy Position Physiotherapist Department Location Fysiotherapy Practice Schaesberg City Landgraaf Country The Netherlands Quote “...”

MAIN PAPER Geraets JJ, Goossens ME, de Groot IJ, de Bruijn CP, de Bie RA, Dinant GJ, van der Heijden G, van den Heuvel WJ. Effectiveness of a graded exercise therapy program for patients with chronic shoulder complaints. Aust J Physiother. 2005;51(2):87-94. PubMed PMID: 15924511.

2006 Name Nadine Goessens PhD defense December 20th 2006 PhD team Van der Graaf, Visseren Speciality Manager Position Manager Department Stichting Trombosedienst Regio Eindhoven Location City Eindhoven Country The Netherlands Quote “...”

MAIN PAPER Goessens BM, Visseren FL, Sol BG, de Man-van Ginkel JM, van der Graaf Y; SMART Study Group. A randomized, controlled trial for risk factor reduction in patients with symptomatic vascular disease: the multidisciplinary Vascular Prevention by Nurses Study (VENUS). Eur J Cardiovasc Prev Rehabil. 2006 Dec;13(6):996-1003. PubMed PMID: 17143135.

20 years Julius Center; 1996-2017 95

2006 Name Colin de Haar PhD defense April 27th, 2006 PhD team Brunekreef, Pieters Speciality Biomedical Science Postdoctoral Researcher Position Department U-DANCE; Laboratory for Translational Immunology; University Medical Center Utrecht Location City Utrecht The Netherlands Country Quote “...”

MAIN PAPER de Haar C, Kool M, Hassing I, Bol M, Lambrecht BN, Pieters R. Lung dendritic cells are stimulated by ultrafine particles and play a key role in particle adjuvant activity. J Allergy Clin Immunol. 2008 May;121(5):1246-54. PubMed PMID: 18313130.

2006 Name Jochem Hogenhuis PhD defense July 5th, 2006 PhD team Van Veldhuisen, Hoes, Voors, Jaarsma Project Management Speciality Team Leader Clinical Studies Position Department Location Nutricia Research City Utrecht Country The Netherlands Quote “...”

MAIN PAPER Hogenhuis J, Voors AA, Jaarsma T, Hoes AW, Hillege HL, Kragten JA, van Veldhuisen DJ. Anaemia and renal dysfunction are independently associated with BNP and NT-proBNP levels in patients with heart failure. Eur J Heart Fail. 2007 Aug;9(8):787-94. PubMed PMID: 17532262.

96 20 years Julius Center; 1996-2017

2006 Name Jolein Iestra PhD defense May 15th, 2006 PhD team Grobbee, van Staveren, Kromhout Speciality Nutritional Epidemiology & Public Health Position Lecturer Department Public Health, Julius Center for Health Sciences and Primary Care University Medical Center Utrecht Location City Utrecht The Netherlands Country Quote “...”

MAIN PAPER Iestra JA, Kromhout D, van der Schouw YT, Grobbee DE, Boshuizen HC, van Staveren WA. Effect size estimates of lifestyle and dietary changes on all-cause mortality in coronary artery disease patients: a systematic review. Circulation. 2005 Aug 9;112(6):924-34. PubMed PMID: 16087812.

2006 Name PhD defense PhD team Speciality Position Department Location City Country Quote

Marjolein Kamphuis November 3rd, 2006 Grobbee, Kromhout, Geerlings General Practice Freelance General Practitioner Health Care Center Respons Hengelo (O) The Netherlands “Waar een wil is, is een weg”

MAIN PAPER Kamphuis MH, Kalmijn S, Tijhuis MA, Geerlings MI, Giampaoli S, Nissinen A, et al. Depressive symptoms as risk factor of cardiovascular mortality in older European men: the Finland, Italy and Netherlands Elderly (FINE) study. Eur J Cardiovasc Prev Rehabil.

2006 Apr;13(2):199-206. PubMed PMID: 16575273.

20 years Julius Center; 1996-2017 97

2006 Name Nienke Katier PhD defense January 20th, 2006 PhD team Kimpen, Verheij, van der Ent, Uiterwaal Speciality Radiology Position Radiologist Department Radiology Location Albert Schweitzer Hospital City Dordrecht Country The Netherlands Quote “...”

MAIN PAPER van Putte-Katier N, van Bommel EF, Elgersma OE, Hendriksz TR. Mesenteric panniculitis: prevalence, clinicoradiological presentation and 5-year follow-up. Br J Radiol. 2014 Dec;87(1044):20140451 PubMed PMID: 25271412.

2006 Name Angela Maas PhD defense September 15th 2006 PhD team Van der Graaf, Mali, van der Schouw Speciality Cardiology Position Professor of cardiology of women Department Cardiology Location Radboud University Medical Center City Nijmegen Country The Netherlands Quote “...”

MAIN PAPER Maas AH, van der Schouw YT, Beijerinck D, Deurenberg JJ, Mali WP, van der Graaf Y. Arterial calcifications seen on mammograms: cardiovascular risk factors, pregnancy, and lactation. Radiology.

2006 Jul;240(1):33-8. PubMed PMID: 16720869.

98 20 years Julius Center; 1996-2017

2006 Name Armanda Matute PhD defense September 12th, 2006 PhD team Hoepelman, Hak Speciality Teaching internal medicine and infectious diseases Position Lecturer Department Internal medicine Location Hospital Escuela Oscar Danilo Rosales Arguello City Leon Country Nicaragua Quote “...”

MAIN PAPER den Engelsen C, van der Werf C, Matute AJ, Delgado E, Schurink CA, Hoepelman AI. Infectious diseases and the use of antibiotics in outpatients at the emergency department of the University Hospital of León, Nicaragua. Int J Infect Dis. 2009 May;13(3):349-54.

PubMed PMID: 18955005.

2006 Name Ruby Meiland PhD defense June 2th, 2006 PhD team Hoepelman, Stolk, Geerlings Speciality Gastroenterology Position Internist-MDL Department Internal Medicine and Gastroenterology Location Gelderse Vallei Hospital City Ede Country The Netherlands Quote “...”

MAIN PAPER Meiland R, Geerlings SE, Stolk RP, Netten PM, Schneeberger PM, Hoepelman AI.Asymptomatic bacteriuria in women with diabetes mellitus: effect on renal function after 6 years of follow-up. Arch Intern Med. 2006 Nov 13;166(20):2222-7. PubMed PMID: 17101940.

20 years Julius Center; 1996-2017 99

2006 Charles Obonyo Name PhD defense September 19th, 2006 PhD team Grobbee Speciality Research Position Chief Research Officer Department Location Kenya Medical Research Institute (KEMRI) City Nairobi Country Kenya Quote “...”

MAIN PAPER Obonyo CO, Vulule J, Akhwale WS, Grobbee DE. In-hospital morbidity and mortality due to severe malarial anemia in western Kenya. Am J Trop Med Hyg. 2007 Dec;77(6 Suppl):23-8. PubMed PMID: 18165471.

2006 Name Jobein Olijhoek PhD defense June 26th, 2006 PhD team Van der Wall, van der Graaf Visseren Speciality Vascular Medicine Position Internist-Vascular Medicine Department Internal Medicine Location Elisabeth-Tweesteden Hospital City Tilburg Country The Netherlands Quote “...”

MAIN PAPER Olijhoek JK, van der Graaf Y, Banga JD, Algra A, Rabelink TJ, Visseren FL; SMART Study Group. The metabolic syndrome is associated with advanced vascular damage in patients with coronary heart disease, stroke, peripheral arterial disease or abdominal aortic aneurysm.

Eur Heart J. 2004 Feb;25(4):342-8. PubMed PMID: 14984924.

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2006 Name Dirk Posthouwer PhD defense June 6th , 2006 PhD team Grobbee, Fischer, Mauser-Bunschoten Speciality Infectious Diseases, Acute Medicine Position Internist Department Internal Medicine Maastricht University Medical Center Location City Maastricht Country The Netherlands Quote “...”

MAIN PAPER Posthouwer D, Voorbij HA, Grobbee DE, Numans ME, van der Bom JG. Influenza and pneumococcal vaccination as a model to assess C-reactive protein response to mild inflammation. Vaccine. 2004 Dec 2;23(3):362-5. PubMed PMID: 15530681.

2006 Name Eline van de Putte PhD defense September 19th, 2006 PhD team Kimpen, Kuis, Uiterwaal, Engelbert Pediatric Medicine Speciality Social Pediatric Medicine Position Department Integrated and Social Pediatric Medicine Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “...”

MAIN PAPER Schouten MC, van Stel HF, Verheij TJ, Houben ML, Russel IM, Nieuwenhuis EE, van de Putte EM. The Value of a Checklist for Child Abuse in Out-of-Hours Primary Care: To Screen or Not to Screen.

PLoS One. 2017 Jan 3;12(1):e0165641. PubMed PMID: 28045904; PubMed Central PMCID: PMC5207629.

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2006 Fleur van Raamt Name PhD defense March 24th, 2006 PhD team Van der Graaf, Mali, Kalmijn Speciality Radiology Position Radiologist Department Radiology Location Gelre Hospital City Apeldoorn Country The Netherlands Quote “...”

MAIN PAPER van Raamt AF, Mali WP, van Laar PJ, van der Graaf Y. The fetal variant of the circle of Willis and its influence on the cerebral collateral circulation. Cerebrovasc Dis. 2006;22(4):217-24. PubMed PMID: 16788293.

2006 Name Karin Rademaker PhD defense November 10th, 2006 PhD team Vries, Grobbee, Uiterwaal, Groenendaal Speciality Neonatology Position Neonatologist Department Neonatology Location University Medical Center Utrecht, Wilhelmina Children Hospital City Utrecht Country The Netherlands Quote “...”

MAIN PAPER Rademaker KJ, de Vries LS, Uiterwaal CS, Groenendaal F, Grobbee DE, van Bel F. Postnatal hydrocortisone treatment for chronic lung disease in the preterm newborn and long-term neurodevelopmental follow-up. Arch Dis Child Fetal Neonatal Ed. 2008 Jan;93(1):F58-63. PubMed PMID: 17848504.

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2006 Name Made Ramadhani PhD defense April 19th, 2006 PhD team Grobbee, Uiterwaal Speciality General Practice General Practitioner Position Department Location Medica Sever, s.r.o City Prague Country Czech Republic “It´s never too late to start anything new“ Quote MAIN PAPER Ramadhani MK, Elias SG, van Noord PA, Grobbee DE, Peeters PH, Uiterwaal CS. Innate left handedness and risk of breast cancer: case-cohort study. BMJ. 2005 Oct 15;331(7521):882-3. PubMed PMID: 16186135;

2006 Name Dieneke Schram-Bijkerk PhD defense February 16th, 2006 PhD team Brunekreef, Doeke Environmental Health Epidemiology Speciality Environmental Epidemiologist Position Department Centre for Sustainability, Environment and Health Location National Institute for Public Health and the Environment (RIVM) City Bilthoven The Netherlands Country “All models are wrong but some are useful” Quote MAIN PAPER Schram-Bijkerk D, van Kempen E, Knol AB, Kruize H, Staatsen B, van Kamp I. Quantitative health impact assessment of transport policies: two simulations related to speed limit reduction and traffic re-allocation in the Netherlands. Occup Environ Med. 2009 Oct;66(10):691-8. PubMed PMID: 19451143.

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2006 Name Wouter Schuiling PhD defense March 9th, 2006 PhD team Rinkel, Algra, Dennesen, de Weerd Speciality Neurology Position Neurologist Department Neurology Location Medical Centre Leeuwarden City Leeuwarden Country The Netherlands Quote “Happiness, Efficiency, Digitize and have fun” MAIN PAPER Schuiling WJ, Dennesen PWJ, Tans JTJ, Kingma LM, Algra A, Rinkel GJE. Troponin I in predicting cardiac or pulmonary complications and outcome in subarachnoid haemorrhage. J Neurol Neurosurg Psychiatry 2005;76:1565-9. PubMed PMID: 16227553.

2006 Name Anouk Speets PhD defense May 12th, 2006 PhD team Mali, Hoes, van der Graaf, Kalmijn Speciality Clinical Epidemiology Position Manager Department Location Pallas, health research and consultancy City Rotterdam Country The Netherlands Quote “Nothing is coincidence” MAIN PAPER Speets AM, van der Graaf Y, Hoes AW, Kalmijn S, Sachs AP, Rutten MJ, et al. Chest radiography in general practice: indications, diagnostic yield and consequences for patient management. Br J Gen Pract. 2006 Aug;56(529):574-8. PubMed PMID: 16882374

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2006 Name Ton Vergouwen PhD defense January 17th, 2006 PhD team Koerselman, Verheij, Burger Speciality Psychiatry Director of residency training in Psychiatry Position Department Psychiatry Onze Lieve Vrouwe Gasthuis Location City Amsterdam Country The Netherlands Quote “...”

MAIN PAPER Haverkamp GL, Torensma B, Vergouwen AC, Honig A. Psychological Distress in the Hospital Setting: A Comparison between Native Dutch and Immigrant Patients. PLoS One. 2015 Jun 25;10(6):e0130961. PubMed PMID: 26110275.

2006 Name Marieke Verschuuren PhD defense May 16th 2006 PhD team van Hout, Bonsel Public Health Speciality Project coordinator Position Department Centre for Prevention and Health Services Research Location National Institute for Public Health and the Environment (RIVM) City Bilthoven The Netherlands Country Quote “...”

MAIN PAPER van Gils PF, Tariq L, Verschuuren M, van den Berg M. Cost-effectiveness research on preventive interventions: a survey of the publications in 2008. Eur J Public Health. 2011 Apr;21(2):260-4. PubMed PMID: 20534690.

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2006 Name Maurits Voormolen PhD defense July 7th, 2006 Mali, van der Graaf, Lampmann, Lohle PhD team Speciality Radiology Position Professor of interventional neuroradiology Department Radiology Location University Hospital Antwerp City Antwerp Country Belgium Quote “...”

MAIN PAPER Voormolen MH, Mali WP, Lohle PN, Fransen H, Lampmann LE, van der Graaf Y, et al. Percutaneous vertebroplasty compared with optimal pain medication treatment: short-term clinical outcome of patients with subacute or chronic painful osteoporotic vertebral compression fractures. The VERTOS study. AJNR Am J Neuroradiol.

2007 Mar;28(3):555-60. PubMed PMID: 17353335.

2006 Name Bart van Wijck PhD defense April 25th, 2006 PhD team Kalkman, Verheij, Moons Speciality Anaesthesiology Position Anaesthesiologist Department Pain Clinic, Anaesthesiology and Intensive Care Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “Een mens lijdt het meest door het lijden dat hij vreest” MAIN PAPER van Wijck AJ, Opstelten W, Moons KG, van Essen GA, Stolker RJ, Kalkman CJ, et al. The PINE study of epidural steroids and local anaesthetics to preventpostherpetic neuralgia: a randomised controlled trial. Lancet. 2006 Jan 21;367(9506):219-24. PubMed PMID: 16427490.

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2006 Iris van Wijk Name PhD defense November 11th, 2006 PhD team Algra, Lindeman, Gorter Speciality Rehabilitation Medicine Position Pediatric rehabilitation physician Department De Hoogstraat Rehabilitation, Brain Centre Rudolf Magnus and Centre of Excellence for Rehabilitation Medicine Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “Enjoy the little things, for one day you may look back and realize they are the big things” MAIN PAPER van Wijk I, Kappelle LJ, van Gijn J, Koudstaal PJ, Franke CL, Vermeulen M, Gorter JW, Algra A, for the LiLAC study group.

Long-term survival and vascular event risk after transient ischaemic attack or minor ischaemic stroke: a cohort study. Lancet 2005;365:2098-104. PubMed PMID: 15964446.

2006 Name Barbara Zwirs PhD defense May 19th, 2006 PhD team Schulpen, Buitelaar, Burger Speciality Psychology Position Associate Professor Department Institute for Criminal Law & Criminology, Leiden Law School Location Leiden University City Leiden Country The Netherlands Quote “...”

MAIN PAPER van Reemst L, Fischer TF, Zwirs BW. Social Information Processing Mechanisms and Victimization: A Literature Review. Trauma Violence Abuse. 2016 Jan;17(1):3-25. PubMed PMID: 25389278.

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Class of

2007

2007 Bellis van der Berg Name PhD defense April 5th, 2007 PhD team Brunekreef, Grievink, Lebret, Yzermans Speciality Health Care Research Position Senior Advisor Research and Monitoring Department Location Vilans Centre of expertise for long-term care City Utrecht Country the Netherlands Quote “...�

MAIN PAPER van den Berg B, Grievink L, van der Velden PG, Yzermans CJ, Stellato RK, Lebret E, Brunekreef B. Risk factors for physical symptoms after a disaster: a longitudinal study. Psychol Med. 2008 Apr;38(4):499510. PubMed PMID: 17892620.

2007 Name Angelique Jansen PhD defense September 26th, 2007 PhD team Sanders, Hoes, Hak Speciality Pediatric Medicine Position We were inable to obtain information through internet and/or personal contact Department Location City Country Quote MAIN PAPER Jansen AG, Sanders EA, Hoes AW, van Loon AM, Hak E. Effects of influenza plus pneumococcal conjugate vaccination versus influenza vaccination alone in preventing respiratory tract infections in children: a randomized, double-blind, placebocontrolled trial. J Pediatr. 2008 Dec;153(6):764-70. PubMed PMID: 18621393.

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2007 Name Kristel Janssen PhD defense December 6th, 2007 PhD team Moons, Grobbee, Vergouwe Speciality Methodology Position Manager Pricing and Reimbursement Department Location Bristol-Myers Squibb City Utrecht Country The Netherlands Quote “...�

MAIN PAPER de Jong LA, Dvortsin E, Janssen KJ, Postma MJ. Cost-effectiveness Analysis for Apixaban in the Acute Treatment and Prevention of Venous Thromboembolism in the Netherlands. Clin Ther. 2017 Feb;39(2):288-302.e4. PubMed PMID: 28139289.

2007 Name M. Meier PhD defense PhD team We were inable to obtain information through internet and/or personal contact Speciality Position Department Location City Country Quote Organisation of acute care.

Demand and supply of emergency care in the region of Utrecht

MAIN PAPER

M. Meier

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2007 Name Suhreta Mujakovic PhD defense December 18th, 2007 PhD team Grobbee, Samsom, de Wit, Numans Speciality Epidemiology & Public Health Senior Epidemiologist Position Department Knowledge & Innovation Public Health Service South (GGD)–Limburg Location City Sittard-Geleen Country The Netherlands Quote “...”

MAIN PAPER Mujakovic S, ter Linde JJ, de Wit NJ, van Marrewijk CJ, Fransen GA, Onland-Moret NC, et al. Serotonin receptor 3A polymorphism c.-42C > T is associated with severe dyspepsia. BMC Med Genet.

2011 Oct 20;12:140. PubMed PMID: 22014438;

2007 Name Leonie Muller - Venmans PhD defense September 11th, 2007 PhD team Rutten, Gorter, Hak Epidemiology of Pediatric Disease Speciality Epidemiologist / guidelines developer Position Department Location Pediatric Association of the Netherlands (Nederlandse vereniging voor Kindergeneeskunde) City Utrecht The Netherlands Country Quote “Anyone who has never made a mistake has never tried anything new.”

MAIN PAPER Muller LM, Gorter KJ, Hak E, Goudzwaard WL, Schellevis FG, Hoepelman AI, Rutten GE. Increased risk of common infections in patients with type 1 and type 2 diabetes mellitus. Clin Infect Dis. 2005 Aug 1;41(3):281-8. PubMed PMID: 16007521

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2007 Name Hamid Nakhai Pour PhD defense July 12th, 2007 Grobbee, Van der Schouw, Verhaar PhD team Speciality Health Technology Assessment Position Staff Member Department Location McMaster University City Hamilton Country Canada Quote “...”

MAIN PAPER Nakhai-Pour HR, Grobbee DE, Emmelot-Vonk MH, Bots ML, Verhaar HJ, van der Schouw YT. Oral testosterone supplementation and chronic low-grade inflammation in elderly men: a 26-week randomized, placebo-controlled trial. Am Heart J. 2007 Dec;154(6):1228. e1-7. PubMed PMID: 18035098.

2007 Name Harmieke van Os-Medendorp PhD defense November 22th, 2007 PhD team Buijnzeel-Koomen, Grypdonck, Bos Speciality Clinical Epidemiology of Dermatology/Allergology Position Epidemiologist Dermatology/Allergology and lecturer Clinical Health Sciences Department Dermatology/Allergology Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “There is a meaning in every journey that is unknown to the traveller”- Bonhoeffer MAIN PAPER van Os-Medendorp H, Koffijberg H, Eland-de Kok PC, van der Zalm A, de Bruin-Weller MS, Pasmans SG, et al. E-health in caring for patients with atopic dermatitis: a randomized controlled cost-effectiveness study of internet-guided monitoring and online self-management training. Br J Dermatol. 2012 May;166(5):1060-8.

PubMed PMID: 22268960.

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2007 Name Sofie van Roosbroeck PhD defense June 4th, 2007 PhD team Brunekreef, Hoek, Janssen Speciality Epidemiology of Cancer Position Coordinator of Centre for Cancer Prevention and Research Group Epidemiology and Social Medicine Department Faculty of Medicine and Health Sciences University of Antwerp Location City Antwerp Country Belgium Quote “The finish line is just the beginning of a whole new race” MAIN PAPER Van Roosbroeck S, Li R, Hoek G, Lebret E, Brunekreef B, Spiegelman D. Traffic-related outdoor air pollution and respiratory symptoms in children: the impact of adjustment for exposure measurement error. Epidemiology. 2008 May;19(3):409-16. PubMed PMID: 18379431.

2007 Name Siamak Sabour PhD defense July 12th, 2007 PhD team Grobbee, Bots Clinical Epidemiology Speciality Position Associate Professor Department Clinical Epidemiology Location Shaheed Beheshti University of Medical Sciences City Tehran Country I.R.Iran Quote “...”

MAIN PAPER Sabour S, Franx A, Rutten A, Grobbee DE, Prokop M, Bartelink ML, van der Schouw YT, Bots ML. High blood pressure in pregnancy and coronary calcification. Hypertension. 2007 Apr;49(4):813-7. PubMed PMID: 17283250.

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2007 Bart Thoolen Name PhD defense October 24th, 2007 PhD team De Ridder, Rutten, Bensing Speciality Clinical Psychology Position Resident in Clinical Pschycologist Department Medical Psychology and Psychiatry Location Gelre Hospital City Apeldoorn Country The Netherlands Quote “The path out of ambivalence is to choose a direction, follow it, and keep moving in the chosen direction” MAIN PAPER Thoolen B, De Ridder D, Bensing J, Maas C, Griffin S, Gorter K, Rutten G. Effectiveness of a self-management intervention in patients with screen-detected type 2 diabetes. Diabetes Care. 2007 Nov;30(11):2832-7. PubMed PMID: 17666461.

2007 Name Martijn Verheus PhD defense May 23rd, 2007 PhD team Grobbee, Peeters, van Gils Speciality Nutritional Epidemiology Position Programme Manager Nutrition & Dietetics Department Nutrition & Dietetics Location The Hague University of Applied Sciences City The Hague Country The Netherlands Quote “...”

MAIN PAPER Verheus M, van Gils CH, Kreijkamp-Kaspers S, Kok L, Peeters PH, Grobbee DE, van der Schouw YT. Soy protein containing isoflavones and mammographic density in a randomized controlled trial in postmenopausal women. Cancer Epidemiol Biomarkers Prev. 2008 Oct;17(10):2632-8. PubMed PMID: 18843004.

116 20 years Julius Center; 1996-2017

2007 Name Leo van Vlimmeren PhD defense April 24th 2007 PhD team Helders, van der Graaf, Engelbert, van Adrichem Speciality Pediatric Physiotherapy Clinician / researcher Position Rehabilitation Department Radboud University Medical Center Location City Nijmegen Country The Netherlands Quote “...”

MAIN PAPER van Vlimmeren LA, van der Graaf Y, Boere-Boonekamp MM, L’Hoir MP, Helders PJ, Engelbert RH. Effect of pediatric physical therapy on deformational plagiocephaly in children with positional preference: a randomized controlled trial. Arch Pediatr Adolesc Med. 2008 Aug;162(8):712-8. PubMed PMID: 18678802.

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2008

2008 Marissa Aanen Fung Kon jin Name PhD defense June 11th, 2008 Smout, Bredenoord, Numans PhD team Speciality General Practice Position General Practitioner Department Location General Practice T.S. Prins City Amsterdam Country The Netherlands Quote “...”

MAIN PAPER Aanen MC, Numans ME, Weusten BL, Smout AJ. Diagnostic value of the Reflux Disease Questionnaire in general practice. Digestion.

2006;74(3-4):162-8. PubMed PMID: 17351321.

2008 Name Auke Appelman PhD defense May 22nd, 2008 PhD team Mali, van der Graaf, Geerlings, Vinken Speciality Radiology Position Neuroradiologist Department Radiology Location University Medical Center Groningen City Groningen Country The Netherlands Quote “Er gaat niets boven Groningen” MAIN PAPER Appelman AP, Vincken KL, van der Graaf Y, Vlek AL, Witkamp TD, Mali WP, Geerlings MI; SMART Study Group. White matter lesions and lacunar infarcts are independently and differently associated with brain atrophy: the SMART-MR study. Cerebrovasc Dis. 2010;29:28-35. PubMed PMID: 19893309.

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2008 Name Liesbeth Bax PhD defense August 29th 2008 PhD team Mali, van der Graaf, Beutler Speciality Radiology Position Radiologist Department Radiology Radboud University Medical Center Location City Nijmegen Country The Netherlands Quote “In patients with atherosclerotic renal artery stenosis and impaired renal function no additional benefit was found in terms of renal function for arterial stent placement as compared to medical treatment alone “ MAIN PAPER Bax L, Woittiez AJ, Kouwenberg HJ, Mali WP, Buskens E, Beek FJ, et al.

Stent placement in patients with atherosclerotic renal artery stenosis and impaired renal function: a randomized trial. Ann Intern Med. 2009 Jun 16;150(12):840-8. PubMed PMID: 19414832.

2008 Name Rob Beelen PhD defense May 6th, 2008 Brunekreef, van de Brandt, Hoek PhD team Environmental Health Epidemiology Speciality Senior scientific researcher Position Department Location National Institute for Public Health and the Environment (RIVM) City Bilthoven The Netherlands Country Quote “...”

MAIN PAPER Beelen R, Raaschou-Nielsen O, Stafoggia M, et al. Effects of longterm exposure to air pollution on natural-cause mortality: an analysis of 22 European cohorts within the multicentre ESCAPE project. Lancet. 2014 Mar 1;383(9919):785-95. PubMed PMID: 24332274.

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2008 Name René Bijkerk PhD defense February 26th, 2008 PhD team Hoes, Knottnerus, de Wit, Muris Speciality General Practice General Practitioner & Trainer General Practitioners Position Department General Practice, Julius Center for Health Sciences and Primary Care Location General Practice de Weerark & University Medical Center Utrecht de Meern & Utrecht City The Netherlands Country Quote “...”

MAIN PAPER Bijkerk CJ, de Wit NJ, Muris JW, Whorwell PJ, Knottnerus JA, Hoes AW. Soluble or insoluble fibre in irritable bowel syndrome in primary care? Randomised placebo controlled trial. BMJ. 2009 Aug 27;339:b3154. PubMed PMID: 19713235.

2008 Name Jettie Bont PhD defense February 15th, 2008 Verheij, Hoes, Hak PhD team General Practice Speciality Position General Practitioner & Head of the department of GP-specialty training Department Location General Practice & Academic Medical Center - University of Amsterdam City Amsterdam Country The Netherlands Quote “If you can’t explain it to a six year old, you don’t understand it yourself.” - Albert Einstein MAIN PAPER Bont J, Hak E, Hoes AW, Macfarlane JT, Verheij TJ. Predicting death in elderly patients with community-acquired pneumonia: a prospective validation study reevaluating the CRB-65 severity assessment tool. Arch Intern Med. 2008 Jul 14;168(13):1465-8. PubMed PMID: 18625928.

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2008 Name Claudia Brandenburg PhD defense September 4th, 2008 PhD team Vosselman, Groenewegen, Schrijvers Speciality Health Economics & Management Position Chair of the Board of Directors Department Location Admiraal de Ruyter Hospital City Goes Country The Netherlands Quote “...”

MAIN PAPER

2008 Name Beate Brouwer PhD defense May 15th, 2008 PhD team Van der Graaf, Visseren Speciality Clinical Research Organisation Position Project Director Department Location PRA Health Sciences City Groningen / Assen Country The Netherlands Quote “...”

MAIN PAPER Brouwer BG, Visseren FL, Algra A, van Bockel JH, Bollen EL, Doevendans PA, et al. Effectiveness of a hospital-based vascular screening programme (SMART)for risk factor management in patients with established vascular disease or type 2 diabetes: a parallel-group comparative study. J Intern Med. 2010 Jul;268(1):83-93. PubMed PMID: 20337856.

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2008 Name Viviane Dietz PhD defense September 2nd, 2008 PhD team Heintz, van der Graaf, van der Vaart, Schraffordt-Koops Gynaecology (Urogynaecology) Speciality Position Gynaecologist Department Obstetrics and Gynaecology Catharina Hospital Eindhoven Location City Eindhoven The Netherlands Country Quote “...”

MAIN PAPER Dietz V, van der Vaart CH, van der Graaf Y, Heintz P, Schraffordt Koops SE. One-year follow-up after sacrospinous hysteropexy and vaginal hysterectomy for uterine descent: a randomized study. Int Urogynecol J. 2010 Feb;21(2):209-16PubMed PMID: 19834635.

2008 Name Soner Dogan PhD defense October 23th, 2008 PhD team Grobbee, Bots Speciality Psychiatry Psychiatrist, Head of department Position Department Psychiatry Location Admiraal De Ruyter Hospital City Goes Country The Netherlands Quote “You tell them what you’re gonna tell them, you tell them, then you tell them what you’ve told them” - John Wayne MAIN PAPER Dogan S, Duivenvoorden R, Grobbee DE, Kastelein JJ, Shear CL, Evans GW,et al. Completeness of carotid intima media thickness measurements depends on body composition: the RADIANCE 1 and 2 trials. J Atheroscler Thromb. 2010 May;17(5):526-35. PubMed PMID: 20228610.

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2008 Name Carline van den Dool PhD defense October 9th, 2008 PhD team Bonten, Hak, Wallinga Speciality Epidemiology of Infectious Disease Position Policy Advisor Project Coordinator Antimicrobial Resistance Department Centre for Infectious Disease Control (CIb) & Centre for Infectious Diseases Epidemiology and Surveillance (EPI) Location National Institute for Public Health and the Environment (RIVM) City Bilthoven Country The Netherlands Quote “Our deepest fear is not that we are inadequate. Our deepest fear is that we are powerful beyond measure” - Marianne Williamson MAIN PAPER van den Dool C, Haenen A, Leenstra T, Wallinga J. The Role of Nursing Homes in the Spread of Antimicrobial Resistance Over the Healthcare Network. Infect Control Hosp Epidemiol. 2016 Jul;37(7):761-7. PubMed PMID: 27052880.

2008 Name Martijn van Eck PhD defense May 15th, 2008 PhD team Van Hemel, Grobbee, Moons Speciality Cardiovascular Epidemiology Position Project manager Department Cardiology Location Jeroen Bosch Hospital City ‘s Hertogenbosch Country The Netherlands Quote “...”

MAIN PAPER van Eck JW, van Hemel NM, Grobbee DE, Buskens E, Moons KG. FOLLOWPACE study: a prospective study on the cost-effectiveness of routine follow-up visits in patients with a pacemaker.

Europace.2006 Jan;8(1):60-4. PubMed PMID: 16627411.

126 20 years Julius Center; 1996-2017

2008 Name Fatima El Fakiri PhD defense March 14th, 2008 PhD team Berg, Hoes, Bruijnzeels Speciality Epidemiology of ageing Senior researcher Position Department Epidemiology, Health Promotion & Care Innovation Public Health Service of Amsterdam Location City Amsterdam The Netherlands Country Quote “...”

MAIN PAPER El Fakiri F, Bruijnzeels MA, Uitewaal PJ, Frenken RA, Berg M, Hoes AW. Intensified preventive care to reduce cardiovascular risk in healthcare centres located in deprived neighbourhoods: a randomized controlled trial. Eur J Cardiovasc Prev Rehabil. 2008 Aug;15(4):488-93. PubMed PMID: 18677177.

2008 Petra Gorter Name PhD defense March 6th, 2008 Van der Graaf, Visseren PhD team Speciality Dermatology Position Dermatologist Department Dermatology Bernhoven Hospital Location City Uden Country The Netherlands “Keep calm and be mindful“ Quote MAIN PAPER Gorter PM, Olijhoek JK, van der Graaf Y, Algra A, Rabelink TJ, Visseren FL; SMART Study Group. Prevalence of the metabolic syndrome in patients with coronary heart disease, cerebrovascular disease, peripheral arterial disease or abdominal aortic aneurysm.

Atherosclerosis. 2004 Apr;173(2):363-9. PubMed PMID: 15064114.

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2008 Gerco Haars Name PhD defense September 9th, 2008 PhD team Grobbee, Peeters, van Noord Speciality Pharmaceutical research and management Position Director Analytics and Outcomes Department Location Teva Pharmaceuticals City Haarlem Country The Netherlands Quote “...”

MAIN PAPER Haars G, van Noord PA, van Gils CH, Grobbee DE, Peeters PH. Measurements of breast density: no ratio for a ratio. Cancer Epidemiol Biomarkers Prev. 2005 Nov;14(11 Pt 1):2634-40. PubMed PMID: 16284389.

2008 Name Gideon Hajer PhD defense February 21th, 2008 PhD team Van der Wall, van der Graaf, Visseren Speciality Vascular Medicine Position Internist-Vascular Medicine Department Internal Medicine Location Deventer Hospital City Deventer Country The Netherlands Quote “...”

MAIN PAPER Hajer GR, van Haeften TW, Visseren FL. Adipose tissue dysfunction in obesity, diabetes, and vascular diseases. Eur Heart J. 2008 Dec;29(24):2959-71. PubMed PMID: 18775919.

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2008 Name Patricia Halkes PhD defense September 30th, 2008 PhD team Algra, Kappelle Speciality Neurology Position Neurologist Department Neurology Noordwest Ziekenhuisgroep Location City Alkmaar Country The Netherlands “Cure sometimes, treat often, comfort always” Quote MAIN PAPER The ESPRIT Study Group. Aspirin plus dipyridamole versus aspirin alone after cerebral ischaemia of arterial origin (ESPRIT): a randomised controlled trial. Lancet 2006;367:1665-1673. Writing committee: Halkes PHA, van Gijn J, Kappelle LJ, Koudstaal LJ, Algra A. PubMed PMID: 16714187.

2008 Name José Hofhuis PhD defense October 8th, 2008 PhD team Bakker, Schrijvers, Spronk, van Stel Nursing Sciences Speciality Position Research coordinator- Nurse- Researcher Intensive Care Department Intensive Care Department Gelre Hospital Location City Apeldoorn The Netherlands Country Quote “...”

MAIN PAPER Hofhuis JG, Spronk PE, van Stel HF, Schrijvers GJ, Rommes JH, Bakker J. The impact of critical illness on perceived health-related quality of life during ICU treatment, hospital stay, and after hospital discharge: a long-term follow-up study. Chest. 2008 Feb;133(2):377-85. PubMed PMID: 17925419.

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2008 Name Paul Janssen PhD defense September 16th, 2008 PhD team Rutten, Stolk, Gorter Speciality General Practice Position General Practitioner Department General Practice & Elderly Care Medicine Location VU University Medical Center Amsterdam & Huisartsenpraktijk Baambrugge City Amsterdam & Baambrugge Country The Netherlands Quote “Better spend your money on experiences, rather than on possessions” MAIN PAPER Janssen PG, Gorter KJ, Stolk RP, Rutten GE. Randomised controlled trial of intensive multifactorial treatment for cardiovascular risk in patients with screen-detected type 2 diabetes: 1-year data from the ADDITION Netherlands study. Br J Gen Pract. 2009 Jan;59(558):43-8.

PubMed PMID: 19105915.

2008 Name Brita de Jong PhD defense January 24th, 2008 PhD team Verheij, van der Ent, Uiterwaal Speciality Social Pediatrics and Pediatric Medicine Position Social Medicine Pediatrician (jeugdarts) Department Social Pediatric Medicine Location Medical Centre Leeuwarden City Leeuwarden Country The Netherlands Quote “...”

MAIN PAPER de Jong BM, van der Ent CK, van der Zalm MM, van Putte-Katier N, Verheij TJ, Kimpen JL, Uiterwaal CS; WHISTLER study group..

Respiratory symptoms in young infancy: child, parent and physician related determinants of drug prescription in primary care. Pharmacoepidemiol Drug Saf. 2009 Jul;18(7):610-8. PubMed PMID: 19399917.

130 20 years Julius Center; 1996-2017

2008 Name Elise van Kempen PhD defense January 22nd, 2008 PhD team Brunekreef, Lebret, Stansfeld, van Kamp Speciality Public Health Epidemiology Senior Researcher Position Department Centre for Sustainability, Environment and Health Location National Institute for Public Health and the Environment (RIVM) City Bilthoven The Netherlands Country Quote “...”

MAIN PAPER van Kempen E, Babisch W. The quantitative relationship between road traffic noise and hypertension: a meta-analysis. J Hypertens.

2012 Jun;30(6):1075-86. PubMed PMID: 22473017.

2008 Mirjam Knol Name PhD defense May 29th, 2008 PhD team Grobbee, Egberts, Geerlings Speciality Epidemiology of Vaccine Preventable Diseases Senior Epidemiologist Position Department Centre for Infectious Disease Control Netherlands (CIb) Location National Institute for Public Health and the Environment (RIVM) City Bilthoven The Netherlands Country Quote “Go for it!“ MAIN PAPER Knol MJ, van der Tweel I, Grobbee DE, Numans ME, Geerlings MI. Estimating interaction on an additive scale between continuous determinants in a logistic regression model. Int J Epidemiol. 2007 Oct;36(5):1111-8. PubMed PMID: 17726040.

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2008 Erik Koffijberg Name PhD defense May 29th, 2008 PhD team Rinkel, van Hout, Buskens Speciality Health Economiy Position Associate Professor Department Health Technology & Services Research Location University of Twente City Enschede Country The Netherlands Quote “Those who say it cannot be done shouldn’t interrupt the people doing it“ MAIN PAPER Koffijberg H, Buskens E, Algra A, Wermer MJ, Rinkel GJ. Growth rates of intracranial aneurysms: exploring constancy. J Neurosurg. 2008 Aug;109(2):176-85. PubMed PMID: 18671627.

2008 Name Laura Koopman PhD defense January 31rd, 2008 PhD team Grobbee, Rovers Speciality Epidemiology of Health Care Quality Position Advisor Healh Care Quality Department Location National Health Care Institute / Zorginstituut Nederland City Diemen Country The Netherlands Quote “...”

MAIN PAPER Koopman L, van der Heijden GJ, Grobbee DE, Rovers MM. Comparison of methods of handling missing data in individual patient data meta-analyses: an empirical example on antibiotics in children with acute otitis media. Am J Epidemiol. 2008 Mar 1;167(5):540-5.

PubMed PMID: 18184640

132 20 years Julius Center; 1996-2017

2008 Name Weinand Laan PhD defense July 13th, 2007 PhD team Grobbee, Kahn, Burger Speciality Data Scientist Team Lead Data Quality Management Position Department Location Textkernel City Amsterdam Country The Netherlands Quote “It might look like I’m doing nothing, but at the cellular level I’m really quite busy.”

MAIN PAPER Laan W, Grobbee DE, Selten JP, Heijnen CJ, Kahn RS, Burger H. Adjuvant aspirin therapy reduces symptoms of schizophrenia spectrum disorders: results from a randomized, double-blind, placebo-controlled trial. J Clin Psychiatry. 2010 May;71(5):520-7.

PubMed PMID: 20492850.

2008 Name Corinne Lebrun PhD defense March 6th, 2008 Lamberts, Grobbee, van der Schouw PhD team Speciality Rheumatology Position Rheumatologist Department Rheumatology Location Saxenburgh groep, Röpcke-Zweers Ziekenhuis City Hardenberg Country The Netherlands Quote “Mijn patiënten behandel ik zoals ik zelf behandeld zou willen worden. De wederzijdse voldoening die daaruit voortvloeit is o verweldigend!”

MAIN PAPER Lebrun CE, van der Schouw YT, de Jong FH, Pols HA, Grobbee DE, Lamberts SW. Relations between body composition, functional and hormonal parameters and quality of life in healthy postmenopausal women. Maturitas. 2006 Aug 20;55(1):82-92. PubMed PMID: 16497451.

20 years Julius Center; 1996-2017 133

2008 Name Anne May PhD defense January 11th, 2008 PhD team Grobbee, Passchier, Ros Speciality Epidemiology of Cancer Position Associate Professor Department Julius Center of Health Sciences and Primary Care Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “Nicht ärgern, nur wundern!”

MAIN PAPER May AM, Korstjens I, van Weert E, van den Borne B, HoekstraWeebers JE, van der Schans CP, et al. Long-term effects on cancer survivors’ quality of life of physical training versus physical training combined with cognitive-behavioral therapy: results from a randomized trial. Support Care Cancer. 2009 Jun;17(6):653-63.

PubMed PMID: 18953578

2008 Name Esther Molenaar PhD defense September 30th, 2008 PhD team Grobbee, Numans, van Ameijden Speciality Epidemiology Position Lecturer (BSc Health and Life Sciences) Department Environment and Health Location VU University Medical Center Amsterdam City Amsterdam Country The Netherlands Quote “...”

MAIN PAPER Molenaar EA, Massaro JM, Jacques PF, Pou KM, Ellison RC, Hoffmann U, et al. Association of lifestyle factors with abdominal subcutaneous and visceral adiposity: the Framingham Heart Study.

Diabetes Care. 2009 Mar;32(3):505-10. PubMed PMID: 19074991.

134 20 years Julius Center; 1996-2017

2008 Name Martijn Pruissen PhD defense April 1st, 2008 PhD team Algra, Kappelle Speciality Neurology Position Neurologist Department Neurology Diakonessenhuis Utrecht Location City Utrecht Country The Netherlands Quote “Reply of Willie Sutton as to why he kept robbing banks: “Because that’s where the money is!”

- Sutton’s law: applicable to medical and scientific hypothesis generation MAIN PAPER Pruissen DMO, Slooter AJC, Rosendaal FR, van der Graaf Y, Algra A. Coagulation factor XIII gene variation, oral contraceptives, and risk of ischemic stroke. Blood 2008;111:1282-6. PubMed PMID: 18006701.

2008 Annemarieke Rutten Name PhD defense February 20th, 2008 Prokop, Bots PhD team Speciality Radiology Position Radiologist Department Radiology Antoni van Leeuwenhoek Hospital Location City Amsterdam Country The Netherlands “The heart of life is good” Quote MAIN PAPER Bleker SM, Beenen LF, Di Nisio M, van Es N, Büller HR, Kraaijpoel N, Rutten A. Incidental pulmonary embolism in cancer patients: Interobserver agreement on the diagnosis and extent with a focus on distal clots. Thromb Res. 2016 Nov;147:46-51. PubMed PMID: 27669127.

20 years Julius Center; 1996-2017 135

2008 Name Salome Scholtens PhD defense June 12th, 2008 Brunekreef, Seidell, Wijga PhD team Speciality Environmental Health Epidemiology Position Programme manager Research Data Services & community manager at the Genomics Coordination Center Department Faculty of Medical Sciences Location University Medical Center Groningen City Groningen Country The Netherlands Quote “...”

MAIN PAPER Vonk JM, Scholtens S, Postma DS, Moffatt MF, Jarvis D, Ramasamy A, et al. Adult onset asthma and interaction between genes and active tobacco smoking: The GABRIEL consortium. PLoS One. 2017 Mar 2;12(3):e0172716. PubMed PMID: 28253294;

2008 Name Eva Suarthana PhD defense June 8th, 2008 PhD team Heederik, Grobbee, Meijer Speciality Clinical Epidemiology Position Professeur chercheur adjoint Department Centre de recherche, Hôpital du Sacré-Cœur de Montréal ; Département de médecine sociale et préventive, École de santé publique, Location University of Montreal City Montreal Country Canada Quote “If you don’t go after what you want, you’ll never have it. If you don’t ask, the answer is always no. If you don’t step forward, you’re always in the same place.”

MAIN PAPER Suarthana E, Moons KG, Heederik D, Meijer E. A simple diagnostic model for ruling out pneumoconiosis among construction workers.

Occup Environ Med. 2007 Sep;64(9):595-601. PubMed PMID: 17409183; 136 20 years Julius Center; 1996-2017

2008 Name Yanto Tjang PhD defense July 10th, 2008 PhD team Grobbee, Körfer, Van der Heijden Speciality Cardio Thoracic Surgery Position Cardio Thoracic Surgeon Department Cardio Thoracic Surgery Premier Jatinegara Hospital Location City Jakarta Country Indonesia Quote “...”

MAIN PAPER Tjang YS, van der Heijden GJ, Tenderich G, Körfer R, Grobbee DE. Long-term results of heart transplantation for end-stage valvular heart disease. J Card Surg. 2009 Sep Oct;24(5):580-4. PubMed PMID: 19740302.

2008 Name Diane Toll PhD defense April 11th, 2008 PhD team Moons, Hoes, Oudega Speciality Position We were inable to obtain information through internet and/or personal contact Department Location City Country Quote MAIN PAPER Toll DB, Janssen KJ, Vergouwe Y, Moons KG. Validation, updating and impact of clinical prediction rules: a review. J Clin Epidemiol.

2008 Nov;61(11):1085-94. PubMed PMID: 19208371.

20 years Julius Center; 1996-2017 137

2008 Sabine Uijl Name PhD defense January 31st, 2008 PhD team van Huffelen, Moons, Leijten Speciality Epidemiology & Education Position Education manager & Epidemiologist Department Julius Academy, Julius Center for Health Sciences and Primary Care Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “Logic will get you from A to B. Imagination will take you everywhere. (Albert Einstein)” MAIN PAPER Uijl SG, Leijten FS, Arends JB, Parra J, van Huffelen AC, Moons KG. Prognosis after temporal lobe epilepsy surgery: the value of combining predictors. Epilepsia. 2008 Aug;49(8):1317-23. PubMed PMID: 18557776.

2008 Name Alike van der Velden PhD defense October 27th, 2008 PhD team Grobbee, Numans Speciality Epidemiology of Infectious Disease in Primary Care Position Assistant Professor & Network EU coordinator Department General Practice, Julius Center for Health Sciences and Primary Care Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “Look well, therefore, to this day!“ MAIN PAPER van der Velden AW, Kuyvenhoven MM, Verheij TJ. Improving antibiotic prescribing quality by an intervention embedded in the primary care practice accreditation: the ARTI4 randomized trial.

J Antimicrob Chemother. 2016 Jan;71(1):257-63. PubMed PMID: 26490015.

138 20 years Julius Center; 1996-2017

2008 Name Floor Vernooij PhD defense March 4th, 2008 PhD team Heintz, van der Graaf, Witteveen Speciality Gynaecology Position Gynaecologist Department Obstetrics and Gynaecology Spaarne Gasthuis Location Haarlem and Hoofddorp City Country The Netherlands Quote “...”

MAIN PAPER Vernooij F, Heintz AP, Coebergh JW, Massuger LF, Witteveen PO, van der Graaf Y. Specialized and high-volume care leads to better outcomes of ovarian cancer treatment in the Netherlands. Gynecol Oncol. 2009 Mar;112(3):455-61. PubMed PMID: 19136148.

2008 Name Hadi Zafarmand PhD defense October 21st, 2008 PhD team Grobbee, Bots Clinical Epidemiology Speciality Position Postdoctoral Researcher Department Public Health and Gynecology Location Academic Medical Center - University of Amsterdam City Amsterdam The Netherlands Country Quote “A day without randomisation is a day without progress. “ MAIN PAPER Tajik P, Monfrance M, van ‘t Hooft J, et al. A multivariable model to guide the decision for pessary placement to prevent preterm birth in women with a multiple pregnancy: a secondary analysis of the ProTWIN trial. Ultrasound Obstet Gynecol. 2016 Jul;48(1):48-55.

PubMed PMID: 26748537.

20 years Julius Center; 1996-2017 139

2008 Name Mira Zuidgeest PhD defense October 8th, 2008 PhD team Leufkens, Brunekreef, Kracke, Smit Speciality Clinical Epidemiology Assistant Professor of Epidemiology Position Department Clinical Epidemiology, Julius Center for Health Sciences and Primary Care University Medical Center Utrecht Location City Utrecht The Netherlands Country Quote “...”

MAIN PAPER Zuidgeest MG, Goetz I, Grobbee DE; WP3 of the GetReal Consortium.. PRECIS-2 in perspective: what is next for pragmatic trials? J Clin Epidemiol. 2016 Mar 6. pii: S0895-4356(16)30006-3. PubMed PMID: 26960164.

140 20 years Julius Center; 1996-2017

Class of

2009

2009 Leon Bax Name PhD defense July 7th, 2009 PhD team Moons Speciality Model-based drug development activities Position Director of Consulting Services Department Location Quantitative Solutions, A Certara Company City Princeton Country United States of America Quote “…”

MAIN PAPER Bax L, Moons KG. Beyond publication bias. J Clin Epidemiol. 2011 May;64(5):459-62. PubMed PMID: 21194886.

2009 Name Rijkel van Bruggen PhD defense March 3rd, 2009 PhD team Rutten, Stolk, Gorter Speciality General Practice Position General Practitioner Department Location General Practice van Bruggen City Apeldoorn Country The Netherlands Quote “Want er moet niets nieuws voorgesteld worden zonder een geldige reden, tenzij het vanzelfsprekend is, of door ervaring bekend of door de autoriteit van de Heilige Schrift bewezen”. Ockham MAIN PAPER van Bruggen R, Gorter KJ, Stolk RP, Verhoeven RP, Rutten GE. Implementation of locally adapted guidelines on type 2 diabetes.

Fam Pract. 2008 Dec;25(6):430-7. PubMed PMID: 18718886.

20 years Julius Center; 1996-2017 145

2009 Pieta Bruggink-Andre de la Porte Name PhD defense January 16th,, 2009 PhD team Hoes, van Veldhuisen Speciality Cardiology Position Deceased, September 29th, 2016 Department Cardiology Location Deventer Hospital City Deventer Country The Netherlands Quote “…”

MAIN PAPER Bruggink-André de la Porte PW, Lok DJ, van Wijngaarden J, Cornel JH, Pruijsers-Lamers D, van Veldhuisen DJ, Hoes AW. Heart failure programmes in countries with a primary care-based health care system. Are additional trials necessary? Design of the DEAL-HF study. Eur J Heart Fail. 2005 Aug;7(5):910-20. PubMed PMID: 16087143.

2009 Name Mariëlle Emmelot-Vonk PhD defense December 1st, 2009 PhD team Van der Schouw, Grobbee Speciality Geriatric Medicine Position Geriatrician, chair of the department Department Geriatric Medicine Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “...”

MAIN PAPER Emmelot-Vonk MH, Verhaar HJ, Nakhai Pour HR, Aleman A, Lock TM, Bosch JL, et al. Effect of testosterone supplementation on functional mobility, cognition, and other parameters in older men: a randomized controlled trial. JAMA. 2008 Jan 2;299(1):39-52.

PubMed PMID: 18167405.

146 20 years Julius Center; 1996-2017

2009 Marieke Ermers Name PhD defense June 2th,, 2009 Kimpen, Bont, Rovers PhD team Speciality Psychiatry Position Child and Adolescent Psychiatrist Department Psyciatry Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “...”

MAIN PAPER Ermers MJ, Rovers MM, van Woensel JB, Kimpen JL, Bont LJ; RSV Corticosteroid Study Group.. The effect of high dose inhaled corticosteroids on wheeze in infants after respiratory syncytial virus infection: randomised double blind placebo controlled trial. BMJ. 2009 Mar 31;338:b897. PubMed PMID: 19336497.

2009 Name Rolf Groenwold PhD defense May 19th,, 2009 PhD team Hoes, Hak Speciality Clinical Epidemiology Position Associate Professor Department Clinical Epidemiology, Julius Center for Health Sciences and Primary Care Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “Schrijven doe je alleen als je een probleem hebt” MAIN PAPER Groenwold RH, Klungel OH, Grobbee DE, Hoes AW. Selection of confounding variables should not be based on observed associations with exposure. Eur J Epidemiol 2011;26:589-93

20 years Julius Center; 1996-2017 147

2009 Name Wenche Klerkx PhD defense November 26th,, 2009 Heintz, Mali, Peeters, Veldhuis PhD team Speciality Gynaecology Position Resident in Gynaecology and Obstetrics Department Obstetrics and Gynaecology Location Radboud University Medical Center City Nijmegen Country The Netherlands Quote “...”

MAIN PAPER Klerkx WM, Veldhuis WB, Spijkerboer AM, van den Bosch MA, Mali WP, Heintz AP, et al. The value of 3.0Tesla diffusion-weighted MRI for pelvic nodal staging in patients with early stage cervical cancer. Eur J Cancer. 2012 Dec;48(18):3414-21. PubMed PMID: 22835781.

2009 Name Mayke Koek PhD defense November 19th,, 2009 PhD team Bruijnzeel – Koomen, Buskens Speciality Public Health Epidemiology Position Senior Epidemiologist Department Centre for Infectious Disease Control (CIb) & Centre for Infectious Diseases Epidemiology and Surveillance (EPI) Location National Institute for Public Health and the Environment (RIVM) City Bilthoven Country The Netherlands Quote “Absence of evidence is not evidence of absence “ MAIN PAPER Koek MB, Buskens E, van Weelden H, Steegmans PH, Bruijnzeel-Koomen CA,Sigurdsson V. Home versus outpatient ultraviolet B phototherapy for mild to severe psoriasis: pragmatic multicentre randomised controlled non-inferiority trial (PLUTO study). BMJ. 2009 May 7;338:b1542. PubMed PMID: 19423623.

148 20 years Julius Center; 1996-2017

2009 Lidwien Lemmens Name PhD defense January 13th,, 2009 PhD team Moons, Kerkkamp Speciality Epidemiology of Quality of Care Position Senior Researcher Department Centre for Quality of Care Location National Institute for Public Health and the Environment (RIVM) City Bilthoven Country The Netherlands Quote “…”

MAIN PAPER Lemmens LC, Kerkkamp HE, van Klei WA, Klazinga NS, Rutten CL, van Linge RH, Moons KG. Implementation of outpatient preoperative evaluation clinics: facilitating and limiting factors. Br J Anaesth.

2008 May;100(5):645-51. PubMed PMID: 18378547.

2009 Name Ingrid Looijmans - van den Akker PhD defense June 25th,, 2009 PhD team Van Delden, Verheij, Hak Speciality General Practice Position General Practitioner Department Location Julius Health Care Centers (Leidsche Rijn Julius Gezondheidscentra) City Utrecht Country The Netherlands Quote “Multitasking is a way of living” MAIN PAPER Looijmans-Van den Akker I, Verheij TJ, Buskens E, Nichol KL, Rutten GE, Hak E. Clinical effectiveness of first and repeat influenza vaccination in adult and elderly diabetic patients. Diabetes Care.

2006 Aug;29(8):1771-6. PubMed PMID: 16873778.

20 years Julius Center; 1996-2017 149

2009 Matthijs Meijs Name PhD defense October 8th,, 2009 PhD team Doevendans, Prokop, Bots, Cramer Speciality Cardiology Position Cardiologist Department Cardiology Location Thorax Center Twente, Medisch Spectrum Twente City Enschede Country The Netherlands Quote “...”

MAIN PAPER Meijs MF, Vergouwe Y, Cramer MJ, Vonken EJ, Velthuis BK, Verton DJ, et al. SMART study group. A prediction model for left ventricular mass in patients at high cardiovascular risk. Eur J Cardiovasc Prev Rehabil. 2010 Dec;17(6):621-7. PubMed PMID: 20814310.

2009 Name Roderick Metz PhD defense May 20th,,2009 PhD team van der Werken, van der Heijden, Verleisdonk Speciality Vascular Surgery Position Vascular Surgeon Department Vascular Surgery Location Spaarne Gasthuis City Haarlem Country The Netherlands Quote “Wantrouw de chirurg met losse veters” MAIN PAPER Metz R, Verleisdonk EJ, van der Heijden GJ, Clevers GJ, Hammacher ER, Verhofstad MH, et al. Acute Achilles tendon rupture: minimally invasive surgery versus nonoperative treatment with immediate full weightbearing--a randomized controlled trial. Am J Sports Med. 2008 Sep;36(9):1688-94. PubMed PMID: 18645042.

150 20 years Julius Center; 1996-2017

2009 Lars Penne Name PhD defense August 25th,, 2009 PhD team Bots, Ter Wee, Blankestijn, Grooteman Speciality Nephrology Position Internist-Nephrologist Department Internal Medicine Location Noordwest Ziekenhuisgroep City Alkmaar Country The Netherlands Quote “...”

MAIN PAPER Grooteman MP, van den Dorpel MA, Bots ML, Penne EL, van der Weerd NC, Mazairac AH, et al. CONTRAST Investigators.. Effect of online hemodiafiltration on all-cause mortality and cardiovascular outcomes. J Am Soc Nephrol. 2012 Jun;23(6):1087-96. PubMed PMID: 22539829

2009 Name Nicky Peters PhD defense April 2nd, 2009 PhD team Mali, Peeters, Bakker Speciality Radiology Position Radiologist, thorax and abdomen Department Radiology Location Zuyderland Medisch Centrum City Heerlen Country The Netherlands Quote “...”

MAIN PAPER Peters NH, Borel Rinkes IH, Zuithoff NP, Mali WP, Moons KG, Peeters PH. Meta-analysis of MR imaging in the diagnosis of breast lesions.

Radiology. 2008 Jan;246(1):116-24. PubMed PMID: 18024435

20 years Julius Center; 1996-2017 151

2009 Jakub Regieli Name PhD defense September 24th, 2009 PhD team Grobbee, Doevendans Speciality Cardiology Position Cardiologist Department Cardiology Location Hartkliniek Flevoland City Lelystad Country The Netherlands Quote “...”

MAIN PAPER Regieli JJ, Doevendans PA, Grobbee DE, Zwinderman AH, van der Graaf Y, Kastelein JJ, Jukema JW. ABCA1 impacts athero-thrombotic risk and 10-year survival in a contemporary secondary prevention setting. Atherosclerosis. 2011 Oct;218(2):457-63. PubMed PMID: 21840005.

2009 Name Jopje Ruskamp PhD defense October 1st, 2009 PhD team Sanders, Brunekreef, Hoekstra, Rovers Speciality Pediatric Medicine Position Pediatrician Department Location University Medical Center Utrecht, Childrens Hospital City Utrecht Country The Netherlands Quote “…”

MAIN PAPER Ruskamp JM, Hoekstra MO, Postma DS, Kerkhof M, Bottema RW, Koppelman GH,et al. Exploring the role of polymorphisms in ficolin genes in respiratory tract infections in children. Clin Exp Immunol.

2009 Mar;155(3):433-40. PubMed PMID: 19220833

152 20 years Julius Center; 1996-2017

2009 Tjarda Scheltens Name PhD defense November 24th, 2009 PhD team Hoes, Grobbee, Bots Speciality General Practice Position General Practitioner Department Location Health Care Center Goverwelle City Gouda Country The Netherlands Quote “...”

MAIN PAPER Scheltens T, de Beus MF, Hoes AW, Rutten FH, Numans ME, Mosterd A, Kors JA, Grobbee DE, Bots ML. The potential yield of ECG screening of hypertensive patients: the Utrecht Health Project.

J Hypertens. 2010 Jul;28(7):1527-33. PubMed PMID: 20574251.

2009 Name Hugo Smeets PhD defense December 10th, 2009 PhD team Hoes, de Wit Speciality Project management Position Project manager Department Location Artsen Zonder Grenzen (Doctors without Borders, Médecins sans Frontières) City Amsterdam Country The Netherlands Quote “…”

MAIN PAPER Smeets HM, Hoes AW, de Wit NJ. Effectiveness and costs of implementation strategies to reduce acid suppressive drug prescriptions: a systematic review. BMC Health Serv Res. 2007 Nov 5;7:177.

PubMed PMID: 17983477.

20 years Julius Center; 1996-2017 153

2009 Name Bernadette Sol-de Rijk PhD defense March 19th,, 2009 Van der Graaf, van der Wall, Visseren PhD team Speciality Nursing Sciences Position PostdDoctoral Researcher and Lecturer Department Amsterdam School of Health Professions Location University of Applied Sciences & University of Amsterdam Academic Medical Center City Amsterdam Country The Netherlands Quote “…”

MAIN PAPER Sol BG, van der Graaf Y, van der Bijl JJ, Goessens BM, Visseren FL. The role of self-efficacy in vascular risk factor management: a randomized controlled trial. Patient Educ Couns. 2008 May;71(2):191-7. PubMed PMID: 18242934.

2009 Name Ghislaine van Thiel PhD defense October 13th, 2009 PhD team van Delden Speciality Medical Ethics Position Associate Professor of Ethics Department Medical Humanities, Julius Center for Health Sciences and Primary Care Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “Professor Einstein begs you to treat your publications for the time being as if he were already dead.”

- Written on Einstein’s behalf by his secretary, Helen Dukas, March 1931, after he was besieged by one manuscript too many. Einstein Archive 46-487.

MAIN PAPER van Andel J, Leijten F, van Delden H, van Thiel G. What makes a good home-based nocturnal seizure detector? A value sensitive design.

PLoS One. 2015 Apr 13;10(4):e0121446. PubMed PMID: 25875320.

154 20 years Julius Center; 1996-2017

2009 Ilonca Vaartjes Name PhD defense November 24th,, 2009 PhD team Bots, Grobbee Speciality Cardiovascular Disease Epidemiology Position Clinical Epidemiologist Department Clinical Epidemiology, Julius Center for Health Sciences and Primary Care Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “...”

MAIN PAPER Vaartjes I, O’Flaherty M, Capewell S, Kappelle J, Bots M. Remarkable decline in ischemic stroke mortality is not matched by changes in incidence. Stroke. 2013 Mar;44(3):591-7. PubMed PMID: 23212165.

2009 Name Carianne Verheugt PhD defense November 5th,, 2009 PhD team Grobbee, Mulder, Uiterwaal Speciality Vascular Medicine Position Internist Department Internal Medicine Location VU University Medical Center Amsterdam City Amsterdam Country The Netherlands Quote “Great minds discuss ideas. Average minds discuss events. Small minds discuss people.“ MAIN PAPER Verheugt CL, Uiterwaal CS, van der Velde ET, Meijboom FJ, Pieper PG, Vliegen HW, et al. Gender and outcome in adult congenital heart disease. Circulation. 2008 Jul 1;118(1):26-32. PubMed PMID: 18559697.

20 years Julius Center; 1996-2017 155

2009 Name Sigrid Vervoort PhD defense November 19th,, 2009 PhD team Hoepelman, Borleffs, Grypdonck Speciality Supporting and coaching oncology nurse specialist & Lecturing in Qualitative research methodology Position Head of department of Clinical Nurse Specialists & Postdoctoral Researcherresearcher and lecturer Department Cancer Center Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “Be yourself no matter what they say” MAIN PAPER Vervoort SC, Borleffs JC, Hoepelman AI, Grypdonck MH. Adherence in antiretroviral therapy: a review of qualitative studies. AIDS. 2007 Jan 30;21(3):271-81. PubMed PMID: 17255734.

2009 Name Anneloes Vlek PhD defense May 26th,, 2009 PhD team Van der Graaf, Visseren Speciality Medical Microbiology Position Medical Microbiologist Department Medical Microbiology and Immunology Location Diakonessenhuis Utrecht City Utrecht Country The Netherlands Quote “…”

MAIN PAPER Vlek AL, Cooper BS, Kypraios T, Cox A, Edgeworth JD, Auguet OT. Clustering of antimicrobial resistance outbreaks across bacterial species in the intensive care unit. Clin Infect Dis. 2013 Jul;57(1):6576. PubMed PMID: 23549524.

156 20 years Julius Center; 1996-2016 1996-2017

2009 Name Sander Vos PhD defense April 23rd, 2009 PhD team Doevendans, Prokop, Bots Speciality Cardiology Position Cardiologist Department Cardiology Bernhoven Hospital Location City Uden Country The Netherlands “Het is zoals het is “ Quote MAIN PAPER de Vos AM, Prokop M, Roos CJ, Meijs MF, van der Schouw YT, Rutten A, et al. Peri-coronary epicardial adipose tissue is related to cardiovascular risk factors and coronary artery calcification in post-menopausal women. Eur Heart J. 2008 Mar;29(6):777-83.

PubMed PMID: 18156138.

2009 Name Annemarie Wassink PhD defense September 22nd, 2009 PhD team Visseren, van der Graaf Speciality Position We were inable to obtain information through internet and/or personal contact Department Location City Country Quote “…”

MAIN PAPER Wassink AM, van der Graaf Y, Olijhoek JK, Visseren FL; SMART Study Group. Metabolic syndrome and the risk of new vascular events and all-cause mortality in patients with coronary artery disease, cerebrovascular disease, peripheral arterial disease or abdominal aortic aneurysm. Eur Heart J. 2008 Jan;29(2):213-23.

20 years Julius Center; 1996-2017 157

2009 Bas van Zaane Name PhD defense November 5th,, 2009 PhD team Moons, Kalkman, Buhre, Nierich Speciality Anaesthesiology Position Medical Director of Pediatric Anaesthesiology Department Pediatric Anaesthesiology Location University Medical Center Utrecht, Children City Utrecht Country The Netherlands Quote “…”

MAIN PAPER van Zaane B, van Klei WA, Buhre WF, Bauer P, Boerma EC, Hoeft A, et al. European Surgical Outcomes Study (EuSOS) group for the Trials groups of the European Society of Intensive Care Medicine and the European Society of Anaesthesiology. Nonelective surgery at night and in-hospital mortality: Prospective observational data from the European Surgical Outcomes Study. Eur J Anaesthesiol. 2015 Jul;32(7):477-85. PubMed PMID: 26001104.

2009 Name Marieke van den Zalm PhD defense December 3rd, 2009 PhD team van der Ent, Verheij, Uiterwaal, Wilbrink Speciality Pediatric Medicine Position Postdoctoral Researcher Department Desmond Tutu TB Centre , Paediatrics and Child Health, Faculty of Medicine and Health Sciences Location Stellenbosch University City Cape Town Country South Africa Quote “…”

MAIN PAPER van der Zalm MM, Uiterwaal CS, Wilbrink B, Koopman M, Verheij TJ, van der Ent CK. The influence of neonatal lung function on rhinovirus-associated wheeze. Am J Respir Crit Care Med. 2011 Jan 15;183(2):262-7. PubMed PMID: 20802166.

158 20 years Julius Center; 1996-2016

Class of

2010

2010 Name Heidi Ammerlaan PhD defense November 11th, 2010 PhD team Bonten, Kluytmans Speciality Internal Medicine - Infectious Disease Internist-Infectious Disease Position Department Internal Medicine Catharina Hospital Eindhoven Location City Eindhoven Country The Netherlands Quote “…”

MAIN PAPER Ammerlaan HS, Kluytmans JA, Berkhout H, Buiting A, de Brauwer EI, van den Broek PJ, et al. MRSA Eradication Study Group.. Eradication of carriage with methicillin-resistant Staphylococcus aureus: effectiveness of a national guideline. J Antimicrob Chemother. 2011 Oct;66(10):2409-17. PubMed PMID: 21719473.

2010 Name Mariëlle van Avendonk PhD defense October 26th, 2010 PhD team Rutten, Gorter, van den Donk Speciality Policy officer with special interest in mental health and palliative care in general practice.

Position Senior scientific staff member and policy officer Department Location Dutch College of General Practitioners (Nederlands Huisartsen Genootschap) City Utrecht The Netherlands Country Quote “People are a lot more than their disease“ MAIN PAPER Vos RC, van Avendonk MJ, Jansen H, Goudswaard AN, van den Donk M, Gorter K, et al. Insulin monotherapy compared with the addition of oral glucose-lowering agents to insulin for people with type 2 diabetes already on insulin therapy and inadequate glycaemic control. Cochrane Database Syst Rev. 2016 Sep 18;9:CD006992. PubMed PMID: 27640062.

20 years Julius Center; 1996-2017 163

2010 Name Florianne Bauer PhD defense December 16th, 2010 PhD team Van der Schouw, Wijmenga, Onland-Moret Speciality Pharmacoepidemiology Position Pharmacovigilance assessor Department Pharmacovigilance Location Medicines Evaluation Board City Utrecht Country The Netherlands Quote “...”

MAIN PAPER Bauer F, Elbers CC, Adan RA, Loos RJ, Onland-Moret NC, Grobbee DE, et al. Obesity genes identified in genome-wide association studies are associated with adiposity measures and potentially with nutrient-specific food preference. Am J Clin Nutr. 2009 Oct;90(4):951-9. PubMed PMID: 19692490.

2010 Name Margriet de Beus PhD defense June 10th, 2010 PhD team Grobbee, Doevendans, Bots, Mosterd Speciality General Practice Position General Practitioner Department Location Huisartsenpraktijk de Beus City Oisterwijk Country The Netherlands Quote “Ambitie, nou gewoon alles“ - Loesje MAIN PAPER Berdowski J, de Beus MF, Blom M, Bardai A, Bots ML, Doevendans PA, et al. Exercise-related out-of-hospital cardiac arrest in the general population: incidence and prognosis. Eur Heart J. 2013 Dec;34(47):3616-23. PubMed PMID: 24096330.

164 20 years Julius Center; 1996-2017

2010 Name Barbara Borkent-Raven PhD defense November 9th, 2010 PhD team van Hout, Bonsel, van der Poel Speciality Data-scientist mental healthcare Position Department Location Dutch Healthcare Authority City Utrecht Country The Netherlands Quote “…”

MAIN PAPER Borkent-Raven BA, Janssen MP, van der Poel CL, Schaasberg WP, Bonsel GJ, van Hout BA. The PROTON study: profiles of blood product transfusion recipients in the Netherlands. Vox Sang. 2010 Jul 1;99(1):54-64. PubMed PMID: 20202179.

2010 Name Lidewij Broekhuizen PhD defense December 9th, 2010 PhD team Moons, Hoes, Verheij, Sachs General Practice Speciality General Practitioner & Assistant Professor Position Department General Practice, Julius Center for Health Sciences and Primary Care Location General practice de Bongerd & University Medical Center Utrecht Borculo & Utrecht City The Netherlands Country Quote “…”

MAIN PAPER Broekhuizen BD, Sachs AP, Verheij TJ, Janssen KJ, Asma G, Lammers JW, et al. Accuracy of symptoms, signs, and C-reactive protein for early chronic obstructive pulmonary disease. Br J Gen Pract. 2012 Sep;62(602):e632-8. PubMed PMID: 22947584.

20 years Julius Center; 1996-2017 165

2010 Name Madeleine Bruins Slot PhD defense November 4th, 2010 Hoes, Glatz, Rutten, van der Heijden PhD team Speciality General Practice Position General Practitioner and medical advisor HCDO Department Location Huisartsenpraktijk Rosing en Bruins Slot & HCDO (Deventer GP Cooperative) and City Deventer and Markelo Country The Netherlands Quote “Less is more” MAIN PAPER Bruins Slot MH, Rutten FH, van der Heijden GJ, Doevendans PA, Mast EG, Bredero AC, et al. Diagnostic value of a heart-type fatty acid-binding protein (H-FABP) bedside test in suspected acute coronary syndrome in primary care. Int J Cardiol. 2013 Sep 30;168(2):1485-9. PubMed PMID: 23332896.

2010 Name Frits Cleveringa PhD defense May 27th, 2010 PhD team Rutten, Gorter, van den Donk Speciality General Practice Position General Practitioner & Teacher at the vocational training in general practice Department Gezondheidshuis & General Practice, Julius Center for Health Sciences and Primary Care Location Gezondheidshuis Stadshagen & University Medical Center Utrecht City Zwolle & Utrecht Country The Netherlands Quote “No improvement without feedback on performance“ MAIN PAPER Cleveringa FG, Gorter KJ, van den Donk M, Rutten GE. Combined task delegation, computerized decision support, and feedback improve cardiovascular risk for type 2 diabetic patients: a cluster randomized trial in primary care. Diabetes Care. 2008 Dec;31(12):2273-5. PubMed PMID: 18796619.

166 20 years Julius Center; 1996-2017

2010 Name Clara Elbers PhD defense October 7th, 2010 PhD team Wijmenga, van der Schouw, Onland-Moret Speciality Lifes Sciences, biotechnology and medical tehcnology Manager Training and Quality Position Department Location Catalyze – Carying Ideas Forward City Utrecht The Netherlands Country “Winnen is belangrijker dan meedoen“ Quote MAIN PAPER Saxena R, Elbers CC, Guo Y, et al. Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. Am J Hum Genet. 2012 Mar 9;90(3):410-25. PubMed PMID: 22325160.

2010 Stijn van Esser Name PhD defense November 16th, 2010 PhD team Van Hillegersberg, Peeters, van den Bosch Speciality Surgery Surgeon Gasteroenterology Position Department Surgery Location Academic Medical Center - University of Amsterdam City Amsterdam The Netherlands Country Quote “…”

MAIN PAPER van Esser S, Peters NH, van den Bosch MA, Mali WP, Peeters PH, Borel Rinkes IH, et al. Surgical outcome of patients with corebiopsy-proven nonpalpable breast carcinoma: a large cohort follow-up study. Ann Surg Oncol. 2009 Aug;16(8):2252-8.

PubMed PMID: 19437077.

20 years Julius Center; 1996-2017 167

2010 Gerrie-Cor de Gast Name PhD defense March 25th, 2010 PhD team Van der Schouw, Grobbee, Samsioe Speciality Nutrional Epidemiology Position Staff member Department Centre for Nutrition, Prevention and Health Services Location National Institute for Public Health and the Environment (RIVM) City Bilthoven Country The Netherlands Quote “Live life to the max!“ MAIN PAPER Gast GC, Grobbee DE, Pop VJ, Keyzer JJ, Wijnands-van Gent CJ, Samsioe GN, Nilsson PM, van der Schouw YT. Menopausal complaints are associated with cardiovascular risk factors. Hypertension. 2008 Jun;51(6):1492-8. PubMed PMID: 18391100.

2010 Name Lotte Gerritsen PhD defense May 18th, 2010 PhD team Van der Graaf, Penninx, Geerlings, Comijs Speciality Neurosciences Position Assistant Professor Department Clinical Psychology & Medical Epidemiology & Biostatistics Location Utrecht University & Karolinska Institute City Utrecht & Stockholm Country The Netherlands & Sweden Quote “To dare is to lose one’s footing momentarily. Not to dare is to lose oneself.”

MAIN PAPER Gerritsen L, Tendolkar I, Franke B, Vasquez AA, Kooijman S, Buitelaar J,et al. BDNF Val66Met genotype modulates the effect of childhood adversity on subgenual anterior cingulate cortex volume in healthy subjects. Mol Psychiatry. 2012 Jun;17(6):597-603. PubMed PMID:21577214.

168 20 years Julius Center; 1996-2017

2010 Name Rieke van der Graaf PhD defense March 4th, 2010 PhD team van Delden Speciality Medical Ethics Assistant Professor of Medical Ethics Position Department Medical Humanities, Julius Center for Health Sciences and Primary Care University Medical Center Utrecht Location City Utrecht The Netherlands Country Quote “...”

MAIN PAPER van Delden JJ, van der Graaf R. Revised CIOMS International Ethical Guidelines for Health-Related Research Involving Humans. JAMA. 2017 Jan 10;317(2):135-136. PubMed PMID: 27923072.

2010 Paut Greebe Name PhD defense April 22th, 2010 PhD team Algra Nursing Subarachnoid Hemorrhages Speciality Nurse Specialist Position Department Neurology and Neurosurgery Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “Never defer a dream until you are too old to enjoy it“ MAIN PAPER Greebe P, Rinkel GJ. Life expectancy after perimesencephalic subarachnoid hemorrhage. Stroke. 2007 Apr;38(4):1222-4. PubMed PMID: 17332451

20 years Julius Center; 1996-2017 169

2010 Name Inge Haeck PhD defense December 2nd, 2010 PhD team Bruijnzeel-Koomen, Knol Speciality Dermatology Position Dermatologist Department Dermatology & Allergy Location Reinier de Graaf Gasthuis City Delft Country The Netherlands Quote “…”

MAIN PAPER Haeck IM, Knol MJ, Ten Berge O, van Velsen SG, de Bruin-Weller MS, Bruijnzeel-Koomen CA. Enteric-coated mycophenolate sodium versus cyclosporin A as long-term treatment in adult patients with severe atopic dermatitis: a randomized controlled trial. J Am Acad Dermatol. 2011 Jun;64(6):1074-84. PubMed PMID: 21458107.

2010 Name Eline van Hattum PhD defense May 18th, 2010 PhD team Moll, Algra, Tangelder Speciality Vascular Surgery Position Fellow Vascular Surgery Department Surgery Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “KISS: Keep It Stupidly Simple.”

MAIN PAPER van Hattum ES, Algra A, Lawson JA, Eikelboom BC, Moll FL, Tangelder MJD. Bleeding increases the risk of ischemic events in patients with peripheral arterial disease. Circulation 2009;120:156976. PubMed PMID: 19805650.

170 20 years Julius Center; 1996-2017

2010 Name Peter Jacobs PhD defense February 2nd, 2010 PhD team Van der Graaf, Mali Speciality Radiology Intervention Radiologist Position Department Radiology & Nuclear Medicine Onze Lieve Vrouwe Gasthuis Location City Amsterdam Country The Netherlands Quote “Oh….maar dat lukt jou wel” - Y. van der Graaf MAIN PAPER Gondrie MJ, Mali WP, Jacobs PC, Oen AL, van der Graaf Y; PROVIDI Study Group. Cardiovascular disease: prediction with ancillary aortic findings on chest CT scans in routine practice. Radiology.

2010 Nov;257(2):549-59. PubMed PMID: 20876722.

2010 Name Mart Janssen PhD defense October 19th, 2010 PhD team van Hout, Bonsel, van der Poel Blood Transfusion Safety Speciality Principal Investigator Position Department Transfusion Technology Assessment Location University Medical Center Utrecht & Sanquin Utrecht & Amsterdam City Country The Netherlands Quote “It’s the known risks we focus on, the unknown we should worry about.”

MAIN PAPER Mapako T, Oei W, van Hulst M, Kretzschmar ME, Janssen MP. Modelling the risk of transfusion transmission from travelling donors. BMC Infect Dis. 2016 Apr 1;16:143. PubMed PMID: 27038919.

20 years Julius Center; 1996-2017 171

2010 Name Anne Knol PhD defense May 20th, 2010 PhD team Lebret, Brunekreef, van der Sluijs Speciality Envrionmental Health Position Campaign leader on transport and air pollution campaigns Department Location Friends of the Earth Netherlands (Milieudefensie) City Utrecht Country The Netherlands Quote “…”

MAIN PAPER Knol AB, Petersen AC, van der Sluijs JP, Lebret E. Dealing with uncertainties in environmental burden of disease assessment.

Environ Health. 2009 Apr 28;8:21. PubMed PMID: 19400963.

2010 Name Arnoud Knoops PhD defense June 24th, 2010 PhD team Van der Graaf, Mali, Geerlings Speciality Radiology Position Radiologist Department Radiology Location Jeroen Bosch Hospital City ‘s Hertogenbosch Country The Netherlands Quote “…”

MAIN PAPER Knoops AJ, van der Graaf Y, Appelman AP, Mali WP, Geerlings MI. Total cerebral blood flow and hippocampal volume in patients with arterial disease. The SMART-MR study. J Cereb Blood Flow Metab.

2009 Oct;29(10):1727-33. PubMed PMID: 19675562.

172 20 years Julius Center; 1996-2017

2010 Name Sabrina Sluiter- Ramwadhdoebe PhD defense December 17th, 2010 PhD team Castelein, Buskens, Sakkers, Beek, Uiterwaal Speciality Health Care Management Senior Advisor Health Care Policy Position Department Location Dutch Society for Surgery (Nederlandse Vereniging voor Heelkunde) City Utrecht The Netherlands Country “Data zijn geen kennis” Quote MAIN PAPER Ramwadhdoebe S, Buskens E, Sakkers RJ, Stahl JE. A tutorial on discrete-event simulation for health policy design and decision making: optimizing pediatric ultrasound screening for hip dysplasia as an illustration. Health Policy. 2009 Dec;93(2-3):143-50. PubMed PMID: 19674809.

2010 Marieke de Regt Name PhD defense December 16th, 2010 Bonten, Willems PhD team Internal Medicine – Infectious Diseases Speciality Internist-Infectious Diseases Position Department Internal Medicine and Infectious Diseases University Medical Center Utrecht Location City Utrecht Country The Netherlands Quote “…”

MAIN PAPER de Regt MJ, van Schaik W, van Luit-Asbroek M, Dekker HA, van Duijkeren E, Koning CJ, et al. Hospital and community ampicillinresistant Enterococcus faecium are evolutionarily closely linked but have diversified through niche adaptation. PLoS One. 2012;7(2):e30319. PubMed PMID: 22363425.

20 years Julius Center; 1996-2017 173

2010 Ellen Roeloffzen Name PhD defense December 10th, 2010 PhD team Batterman, van Vulpen, Monninkhof Speciality Radiotherapy Position Specialist in radiation therapy in oncology Department Radiotherapy Location Isala Hospital City Zwolle Country The Netherlands Quote “Genieten van het leven doe je ook vandaag: morgen is vaak de drukste dag van de week - Theo Kaandorp“ MAIN PAPER Roeloffzen EM, van Vulpen M, Battermann JJ, van Roermund JG, Saibishkumar EP, Monninkhof EM. Pretreatment nomogram to predict the risk of acute urinary retention after I-125 prostate brachytherapy. Int J Radiat Oncol Biol Phys. 2011 Nov 1;81(3):73744. PubMed PMID: 20888131.

2010 Name Maarten Schmitt PhD defense January 26th, 2010 PhD team Helders, van der Graaf, van Meeteren, de Wijer Speciality Physiotherapy Position Lecturer Department Research Centre Innovations in Care Location Rotterdam University of Applied Sciences City Rotterdam Country The Netherlands Quote “…”

MAIN PAPER Schmitt MA, de Wijer A, van Genderen FR, van der Graaf Y, Helders PJ, van Meeteren NL. The Neck Bournemouth Questionnaire cross-cultural adaptation into Dutch and evaluation of its psychometric properties in a population with subacute and chronic whiplash associated disorders. Spine (Phila Pa 1976). 2009 Nov 1;34(23):2551-61. PubMed PMID: 19927105.

174 20 years Julius Center; 1996-2017

2010 Name Nadia Sutedja PhD defense May 26th, 2010 PhD team Van den Berg, Wokke, Fischer, Veldink Speciality Clinical Neurophysiology Neurologist & Clinical Neurophysiologist Position Department Clinical Neurophysiology Maastricht University Medical Center Location City Maastricht Country The Netherlands Quote “…”

MAIN PAPER Sutedja NA, Veldink JH, Fischer K, Kromhout H, Heederik D, Huisman MH, et al. Exposure to chemicals and metals and risk of amyotrophic lateral sclerosis: a systematic review. Amyotroph Lateral Scler. 2009 Oct-Dec;10(5-6):302-9. PubMed PMID:19922117.

2010 Name Erwin van der Veen PhD defense March 9th, 2010 PhD team Sanders, Schilder, Rovers Ear, Nose, and Throat Medicine Speciality Ear, Nose, and Throat Physician Position Department Otorhinolaryngology & Otolaryngology Head and Neck Surgery Location University Medical Center Utrecht & Central Military Hospital City Utrecht The Netherlands Country Quote “…”

MAIN PAPER Bruijnzeel H, van den Aardweg MT, Grolman W, Stegeman I, van der Veen EL. A systematic review on the surgical outcome of preauricular sinus excision techniques. Laryngoscope. 2016 Jul;126(7):1535-44. PubMed PMID: 27320109.

20 years Julius Center; 1996-2017 175

2010 Name Miranda Velthuis PhD defense October 9th, 2010 PhD team Peeters, van der Wall, May, Monninkhof Speciality Epidemiology of Cancer Position Advisor Department Location Netherlands Comprehensive Cancer Organisation (IKNL) City Utrecht Country The Netherlands Quote “Don’t love your dream, but live your dream “ MAIN PAPER Velthuis MJ, Agasi-Idenburg SC, Aufdemkampe G, Wittink HM. The effect of physical exercise on cancer-related fatigue during cancer treatment: a meta-analysis of randomised controlled trials.

Clin Oncol (R Coll Radiol). 2010 Apr;22(3):208-21. PubMed PMID: 20110159.

2010 Name Marjan Wassenberg PhD defense November 11th, 2010 PhD team Bonten, Kluytmans Speciality Internal Medicine – Infectious diseases Position Internist-Infectious diseases Department Internal Medicine and Infectious Diseases Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “Er zitten 24 uur in een dag, en dan heb je de nacht nog.”

MAIN PAPER Wassenberg MW, Kluytmans JA, Box AT, Bosboom RW, Buiting AG, van Elzakker EP, et al. Rapid screening of methicillin-resistant Staphylococcus aureus using PCR and chromogenic agar: a prospective study to evaluate costs and effects. Clin Microbiol Infect.

2010 Dec;16(12):1754-61. PubMed PMID: 20219077.

176 20 years Julius Center; 1996-2017

2010 Name Marjolein de Weerd PhD defense May 20th, 2010 PhD team Bots, Buskens, Greving Speciality Public Health Epidemiology Position Advisor Department Knowledge Institute of Medical Specialists (Kennisinstituut van Medisch Specialisten) Dutch Federation Medical Specialists Location City Utrecht The Netherlands Country Quote “….”

MAIN PAPER de Weerd M, Greving JP, Hedblad B, Lorenz MW, Mathiesen EB, O’Leary DH,et al. Prediction of asymptomatic carotid artery stenosis in the general population: identification of high-risk groups. Stroke.

2014 Aug;45(8):2366-71. PubMed PMID: 24994719

2010 Name Michelle Westerhuis PhD defense January 7th, 2010 PhD team Visser, Moons, Kwee Speciality Gynaecology Position Gynaecologist Department Obstetrics and Gynaecology Location Maxima Medical Center City Veldhoven Country The Netherlands Quote “…”

MAIN PAPER Westerhuis ME, Visser GH, Moons KG, Zuithoff N, Mol BW, Kwee A. Cardiotocography plus ST analysis of fetal electrocardiogram compared with cardiotocography only for intrapartum monitoring: a randomized controlled trial. Obstet Gynecol. 2011 Feb;117(2 Pt 1):406-7. PubMed PMID: 21252763.

20 years Julius Center; 1996-2017 177

2010 Name Annemieke van Winden PhD defense April 15th, 2010 PhD team Beijnen, Peeters, van Gils, Vermeulen Speciality Epidemiology of Cancer Position Postdoctoral Researcher Department Psychosocial research and Epidemiology Location Netherlands Cancer Institute City Amsterdam Country The Netherlands Quote “Epidemiologie bestudeert grote aantallen, maar wat uiteindelijk echt telt is de waarde ervan voor het individu“ MAIN PAPER van Winden AW, Gast MC, Beijnen JH, Rutgers EJ, Grobbee DE, Peeters PH, van Gils CH. Validation of previously identified serum biomarkers for breast cancer with SELDI-TOF MS: a case control study. BMC Med Genomics. 2009 Jan 19;2:4. PubMed PMID: 19152674

2010 Name Ineke van der Wulp PhD defense February 25th, 2010 PhD team Schrijvers, van Stel Speciality Health Care and ICT Position Software consultant Department Location Chipsoft City Amsterdam Country The Netherlands Quote “…”

MAIN PAPER van der Wulp I, Sturms LM, Schrijvers AJ, van Stel HF. An observational study of patients triaged in category 5 of the Emergency Severity Index. Eur J Emerg Med. 2010 Aug;17(4):208-13. PubMed PMID:19820400.

178 20 years Julius Center; 1996-2017

Class of

2011

2011 Name Nirmala Bhoo Pathy PhD defense November 25th, 2011 PhD team Peeters, van der Graaf, Bulgiba, van Gils, Verkooijen Speciality Clinical Epidemiology Associate Professor Position Department Faculty of Medicine University of Malaya Location Kuala Lumpur City Country Malaysia “Perpetual optimism is a force multiplier “ Quote MAIN PAPER Bhoo Pathy N, Yip CH, Hartman M, Uiterwaal CS, Devi BC, Peeters PH, et al. Breast cancer research in Asia: adopt or adapt Western knowledge? Eur J Cancer. 2013 Feb;49(3):703-9. PubMed PMID: 23040889.

2011 Name Jilles Bijker PhD defense December 7th, 2011 PhD team Kalkman, Moons Speciality Anaesthesiology Position Anaesthesiologist Department Anaesthesiology Location Gelderse Vallei Hospital City Ede Country The Netherlands Quote “...”

MAIN PAPER Bijker JB, Persoon S, Peelen LM, Moons KG, Kalkman CJ, Kappelle LJ, van Klei WA. Intraoperative hypotension and perioperative ischemic stroke after general surgery: a nested case-control study.

Anesthesiology. 2012 Mar;116(3):658-64. PubMed PMID: 22277949.

20 years Julius Center; 1996-2017 183

2011 Geartsje Boonstra Name PhD defense April 12th, 2011 PhD team Kahn, Grobbee, Burger, van Haren Speciality Psychiatry Position Psychiatrist Department Functional Assertive Community Treatment Location Altrecht GGZ City Utrecht Country The Netherlands Quote “When you let go, both your hands are free” MAIN PAPER Boonstra G, Burger H, Grobbee DE, Kahn RS. Antipsychotic prophylaxis is needed after remission from a first psychotic episode in schizophrenia patients: results from an aborted randomised trial.

Int J Psychiatry Clin Pract. 2011 Jun;15(2):128-34. PubMed PMID: 22121861.

2011 Name Özlem Bozkurt PhD defense March 3rd, 2011 PhD team De Boer, Grobbee, Klungel Speciality Pharmacoepidemiology Position Environmental Health Expert Department Location Vlaams Agentschap Zorg en Gezondheid City Brussels Country Belgium Quote “...”

MAIN PAPER Bozkurt O, de Boer A, Grobbee DE, de Leeuw PW, Kroon AA, Schiffers P, Klungel OH. Variation in Renin-Angiotensin system and salt-sensitivity genes and the risk of diabetes mellitus associated with the use of thiazide diuretics. Am J Hypertens. 2009 May;22(5):545-51. PubMed PMID: 19247266.

184 20 years Julius Center; 1996-2017

2011 Name Mandy Conijn PhD defense April 28th, 2011 PhD team Luijten, Mali, Geerlings, Hendrikse Speciality Radiology Fellow Neuro /Head and Neck radiology Position Department Radiology Location Medical Center Haaglanden, Bronovo & Leiden University Medical Center City The Hague & Leiden The Netherlands Country Quote “…”

MAIN PAPER Conijn MM, Kloppenborg RP, Algra A, Mali WP, Kappelle LJ, Vincken KL, et al. SMART Study Group. Cerebral small vessel disease and risk of death, ischemic stroke, and cardiac complications in patients with atherosclerotic disease: the Second Manifestations of ARTerial disease-Magnetic Resonance (SMART-MR) study. Stroke. 2011 Nov;42(11):3105-9. PubMed PMID: 21868739.

2011 Marieke Dijkema Name PhD defense December 20th, 2011 Brunekreef, Gehring, van Strien PhD team Environmental Health Epidemiology Speciality Senior Advisor Environmental Health Position Department Location Public Health Service Amsterdam (GGD) City Amsterdam Country The Netherlands Quote “...”

MAIN PAPER Dijkema MB, Gehring U, van Strien RT, van der Zee SC, Fischer P, Hoek G, Brunekreef B. A comparison of different approaches to estimate small-scale spatial variation in outdoor NO₂ concentrations. Environ Health Perspect. 2011 May;119(5):670-5. PubMed PMID: 21193385;

20 years Julius Center; 1996-2017 185

2011 Name Frans Fluttert PhD defense January 11th, 2011 PhD team Grypdonck, Nijman, van Meijel Speciality Psychiatry Position Associate Professor / Senior Researcher Department Centre for Research and Education in Forensic Psychiatry Location Oslo University Hospital & Molde University College & University of Southern Denmark City Oslo Country Norway Quote “…”

MAIN PAPER Fluttert F, Van Meijel B, Webster C, Nijman H, Bartels A, Grypdonck M. Risk management by early recognition of warning signs in patients in forensic psychiatric care. Arch Psychiatr Nurs. 2008 Aug;22(4):208-16. PubMed PMID: 18640540.

2011 Name Geert-Jan Geersing PhD defense September 27th, 2011 PhD team Moons, Hoes, Oudega, Janssen Speciality General Practice Position General Practitioner & Associate Professor Department General Practice, Julius Center for Health Sciences and Primary Care Location General Practice Buitenhof & University Medical Center Utrecht City Amsterdam & Utrecht Country The Netherlands Quote “…”

MAIN PAPER Geersing GJ, Zuithoff NP, Kearon C, Anderson DR, Ten Cate-Hoek AJ, Elf JL, et al. Exclusion of deep vein thrombosis using the Wells rule in clinically important subgroups: individual patient data meta-analysis. BMJ. 2014 Mar 10;348:g1340. PubMed PMID: 24615063;

186 20 years Julius Center; 1996-2017

2011 Name Carolien Geerts PhD defense May 12th, 2011 PhD team Grobbee, Uiterwaal Speciality Teaching midwife students in physiology and methodology Position Lecturer Department Academy for Midwifery VU University Medical Center Amsterdam Location City Amsterdam The Netherlands Country “…The best is yet to come… “ Quote MAIN PAPER Zhao Y, Zhang J, Hukkelhoven C, Offerhaus P, Zwart J, Jonge Ad, Geerts C. Modest Rise in Caesarean Section from 2000-2010: The Dutch Experience. PLoS One. 2016 May 18;11(5):e0155565. PubMed PMID: 27192534

2011 Name Martijn Gondrie PhD defense March 31st, 2011 PhD team Van der Graaf, Mali Speciality Radiology Resident in Radiology Position Department Radiology Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “…”

MAIN PAPER Gondrie MJ, Mali WP, Jacobs PC, Oen AL, van der Graaf Y; PROVIDI Study Group.Cardiovascular disease: prediction with ancillary aortic findings on chest CT scans in routine practice. Radiology. 2010 Nov;257(2):549-59. PubMed PMID: 20876722.

20 years Julius Center; 1996-2017 187

2011 Haitske Graveland Name PhD defense September 29th, 2011 PhD team Heederik, Wagenaar Speciality Veterinary Medicine Position Reseach Project Manager Department Faculty of Veterinary Sciences Location Utrecht University City Utrecht Country The Netherlands Quote “…”

MAIN PAPER Graveland H, Wagenaar JA, Bergs K, Heesterbeek H, Heederik D. Persistence of livestock associated MRSA CC398 in humans is dependent on intensity of animal contact. PLoS One. 2011 Feb 9;6(2):e16830. PubMed PMID: 21347386.

2011 Name Wim Groen PhD defense December 15th, 2011 PhD team Helders, Biesma, Fischer, van der Net Speciality Cancer Epidemiology Position Postdoctoral Researcher Department Psychosocial Research and Epidemiology Location Netherlands Cancer Institute City Amsterdam Country The Netherlands Quote “…”

MAIN PAPER Groen W, van der Net J, Lacatusu AM, Serban M, Helders PJ, Fischer K. Functional limitations in Romanian children with haemophilia: further testing of psychometric properties of the Paediatric Haemophilia Activities List. Haemophilia. 2013 May;19(3):e116-25.

PubMed PMID: 23374095.

188 20 years Julius Center; 1996-2017

2011 Name Joris de Groot PhD defense September 13th, 2011 PhD team Moons, Bossuyt, Janssen, Reitsma Speciality Clinical Epidemiology Clinical Trial Manager Position Department Image Guided Therapy Systems Philips Healthcare Location City Best Country The Netherlands Quote “Medical science is making such remarkable progress that soon none of us will be well.”

- Aldous Huxley MAIN PAPER de Groot JA, Naaktgeboren CA, Reitsma JB, Moons KG. Methodologic approaches to evaluating new highly sensitive diagnostic tests: avoiding overdiagnosis. CMAJ. 2016 Jul 4. pii: cmaj.150999.

PubMed PMID: 27378465.

2011 Name Charles Helsper PhD defense December 15th, 2011 de Wit, Bonten, van Essen PhD team Epidemiology of Cancer in General Practice Speciality Senior researcher, Lecturer Position Department General Practice, Julius Center for Health Sciences and Primary Care University Medical Center Utrecht Location City Utrecht The Netherlands Country Quote “Research and Innovation can be key tools for optimal patient care, but only in the hands of capable mechanics“ – Own quote MAIN PAPER Helsper CW, Borkent-Raven BA, de Wit NJ, van Essen GA, Bonten MJ, Hoepelman AI, et al. Cost-effectiveness of targeted screening for hepatitis C in The Netherlands. Epidemiol Infect. 2012 Jan;140(1):58-69. PubMed PMID: 21324216.

20 years Julius Center; 1996-2017 189

2011 Name Anneke Hendrix PhD defense April 21st, 2011 PhD team Doevendans, Bots, de Wilde, Mosterd Speciality Cardiology Position Resident in Cardiology Department Cardiology, Divison Heart & Lungs Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “…”

MAIN PAPER van der Werf C, Hendrix A, Birnie E, Bots ML, Vink A, Bardai A, et al.

Improving usual care after sudden death in the young with focus on inherited cardiac diseases (the CAREFUL study): a community-based intervention study. Europace. 2016 Apr;18(4):592-601.

PubMed PMID: 25833117.

2011 Name Karel Hinnen PhD defense April 12th, 2011 PhD team Batterman, van Vulpen, Monninkhof Speciality Radiation therapy (oncology) Position Specialist in radiation therapy in oncology Department Radiation Oncology Location Academic Medical Center - University of Amsterdam City Amsterdam Country The Netherlands Quote “Success consists of going from failure to failure without loss of enthusiasm - Winston Churchill” MAIN PAPER Hinnen KA, Schaapveld M, van Vulpen M, Battermann JJ, van der Poel H, van Oort IM, et al. Prostate brachytherapy and second primary cancer risk: a competitive risk analysis. J Clin Oncol. 2011 Dec 1;29(34):4510-5. PubMed PMID: 22025166.

190 20 years Julius Center; 1996-2017

2011 Name Jita Hoogerduijn PhD defense April 19th, 2011 PhD team Schuurmans, Grobbee Speciality Nursing Sciences into Care for the Chronically ill Associate professor Position Department Research Group Care for the Chronically Ill, Faculty of Health Care University of Applied Sciences Utrecht Location City Utrecht The Netherlands Country Quote “…”

MAIN PAPER Hoogerduijn JG, Buurman BM, Korevaar JC, Grobbee DE, de Rooij SE, Schuurmans MJ. The prediction of functional decline in older hospitalised patients. Age Ageing. 2012 May;41(3):381-7. PubMed PMID: 22378613.

2011 Name Michiel Houben PhD defense June 16th, 2011 PhD team Kimpen, Visser, Bont, Rovers Pediatric Medicine Speciality Position Pediatrician Department General Pediatrics Location Childrens Hospital, University Medical Center Utrecht City Utrecht The Netherlands Country Quote “…”

MAIN PAPER Houben ML, Coenjaerts FE, Rossen JW, Belderbos ME, Hofland RW, Kimpen JL, et al. Disease severity and viral load are correlated in infants with primary respiratory syncytial virus infection in the community. J Med Virol. 2010 Jul;82(7):1266-71. PubMed PMID: 20513094.

20 years Julius Center; 1996-2017 191

2011 Name Simone de Jong PhD defense December 8th, 2011 PhD team Ophoff, Box, Kas Speciality Genetics in Psychiatry Position Postdoctoral Researcher Department Institute of Psychiatry Location Kings College London City London Country United Kingdom Quote “…”

MAIN PAPER de Jong S, Boks MP, Fuller TF, Strengman E, Janson E, de Kovel CG, et al. A gene co-expression network in whole blood of schizophrenia patients is independent of antipsychotic-use and enriched for brain-expressed genes. PLoS One. 2012;7(6):e39498. PubMed PMID: 22761806.

2011 Name Irene Jongerden PhD defense May 21st, 2011 PhD team Bonten, Kesecioglu Speciality Nursing Sciences Position Senior Researcher Department EMGO & Social Medicine Location VU University Medical Center Amsterdam City Amsterdam Country The Netherlands Quote “Face challenges instead of problems.“ MAIN PAPER Jongerden IP, Slooter AJ, Peelen LM, Wessels H, Ram CM, Kesecioglu J, Schneider MM, van Dijk D. Effect of intensive care environment on family and patient satisfaction: a before-after study. Intensive Care Med. 2013 Sep;39(9):1626-34. PubMed PMID: 23740277.

192 20 years Julius Center; 1996-2017

2011 Name Mariska de Jongh PhD defense September 27th, 2011 PhD team Leenen, Schrijvers, Verhofstad Speciality Clinical Epidemiology of Acute Care Clinical Epidemiologist Position Department Acute Care Location Acute Care Brabant & Elisabeth-TweeSteden Hospital City Tilburg Country The Netherlands Quote “…”

MAIN PAPER Veen EJ, Janssen-Heijnen ML, Bosma E, de Jongh MA, Roukema JA. The accuracy of complications documented in a prospective complication registry. J Surg Res. 2012 Mar;173(1):54-9. PubMed PMID: 20934713.

2011 Name Jan Jukema PhD defense January 25th, 2011 PhD team Grypdonck, Verkerk Nursing and Gerontology Speciality Professor of Nursing Position Department Research Centre for Health Care, Social Work & Technology Saxion University of Applied Sciences Location City Deventer and Enschede The Netherlands Country Quote “...”

MAIN PAPER Jukema JS, Harps-Timmerman A, Stoopendaal A, Smits CH. A care improvement program acting as a powerful learning environment to support nursing students learning facilitation competencies.

Nurse Educ Pract. 2015 Nov;15(6):457-62. PubMed PMID: 26004744.

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2011 Name Marije Koopman PhD defense January 13th, 2011 PhD team Van der Ent, Arets, Uiterwaal Speciality Position We were inable to obtain information through internet and/or personal contact Department Location City Country The Netherlands Quote “…”

MAIN PAPER Koopman M, Arets HG, Uiterwaal CS, van der Ent CK. Comparing 6 and 10 sec exhalation time in exhaled nitric oxide measurements in children. Pediatr Pulmonol. 2009 Apr;44(4):340-4. PubMed PMID: 19291761.

2011 Name Albert Mazairac PhD defense December 15th, 2011 PhD team Bots, Nubé, Blankestijn Speciality Radiology Position Fellow in Radiology Department Radiology Location St. Antonius Hospital Nieuwegein City Nieuwegein Country The Netherlands Quote “I fear not the man who has practiced 10,000 kicks once, but I fear the man who has practiced one kick 10,000 times - Bruce Lee” MAIN PAPER Mazairac AH, de Wit GA, Grooteman MP, Penne EL, van der Weerd NC, den Hoedt CH, et al. CONTRAST Investigators.. Effect of hemodiafiltration on quality of life over time. Clin J Am Soc Nephrol. 2013 Jan;8(1):82-9. PubMed PMID: 23124783.

194 20 years Julius Center; 1996-2017

2011 Name Dennis Nieuwkamp PhD defense December 21st, 2011 PhD team Rinkel, Algra Speciality Neurology Position Neurologist Department Neurology Jeroen Bosch Hospital Location ‘s Hertogenbosch City Country The Netherlands Quote “When we strive to become better than we are, everything around us becomes better too” - Paulo Coelho MAIN PAPER Nieuwkamp DJ, Murk JL, van Oosten BW, Cremers CH, Killestein J, Viveen MC, et al. PML in Dutch MS Patients Consortium.. PML in a patient without severe lymphocytopenia receiving dimethyl fumarate. N Engl J Med. 2015 Apr 9;372(15):1474-6. PubMed PMID: 25853764.

2011 Name Marie-Elise Nijdam PhD defense December 7th, 2011 Bots, Grobbee, Franx, Janssen PhD team Youth Health Care Physician Speciality Position Physician Department Public Health Care Centre Utrecht (GGD Location City Amersfoort Country The Netherlands Quote “Children are not a distraction from more important work. They are the most important work”. C.S. Lewis MAIN PAPER Nijdam ME, Janssen KJ, Moons KG, Grobbee DE, van der Post JA, Bots ML, Franx A. Prediction model for hypertension in pregnancy in nulliparous women using information obtained at the first antenatal visit. J Hypertens. 2010 Jan;28(1):119-26.PubMed PMID: 19907344.

20 years Julius Center; 1996-2017 195

2011 Sadegh Samadi Name PhD defense November 28th, 2011 PhD team Heederik, Wouters Speciality Environmental Health Epidemiology Position Fellow Department Environmental Epidemiology, Institute for Risk Assessment Sciences Location Utrecht University City Utrecht Country The Netherlands Quote “…”

MAIN PAPER Samadi S, Wouters IM, Heederik DJ. A review of bio-aerosol exposures and associated health effects in veterinary practice. Ann Agric Environ Med. 2013;20(2):206-21. PubMed PMID: 23772565.

2011 Name Ivonne Sluis PhD defense March 31st, 2011 PhD team Van der Schouw, Beulens Speciality Nutrional Epidemiology Position Assistant Professor Department Clinical Epidemiology, Julius Center for Health Sciences and Primary Care Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “...”

MAIN PAPER Sluijs I, Forouhi NG, Beulens JW, van der Schouw YT, Agnoli C, Arriola L, et al. InterAct Consortium. The amount and type of dairy product intake and incident type 2 diabetes: results from the EPIC-InterAct Study. Am J Clin Nutr. 2012 Aug;96(2):382-90. PubMed PMID: 22760573.

196 20 years Julius Center; 1996-2017

2011 Bauke Stegenga Name PhD defense June 8th, 2011 PhD team Grobbee, King, Geerlings Speciality Oncology Position Associate Director Department Head Quarters Medical Oncology Location Bristol-Myers Squibb City Utrecht Country The Netherlands Quote “...”

MAIN PAPER Stegenga BT, King M, Grobbee DE, Torres-González F, Švab I, Maaroos HI, et al. Differential impact of risk factors for women and men on the risk of major depressive disorder. Ann Epidemiol. 2012 Jun;22(6):388-96. PubMed PMID: 22625996.

2011 Name Marja Stuifbergen PhD defense January 25th, 2011 PhD team van Delden, Dykstra Speciality Research administration and communication for the Nord-Trøndelag Health Study.

Position Advisor Department HUNT Research Centre Location Norwegian University for Science and Technology City Levanger / Trondheim Country Norway Quote “...”

MAIN PAPER Stuifbergen MC, Van Delden JJ. Filial obligations to elderly parents: a duty to care? Med Health Care Philos. 2011 Feb;14(1):63-71.

PubMed PMID: 20922568

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2011 Name Tim Timmers PhD defense May 26th, 2011 Leenen, Moons, Verhofstad PhD team Speciality Surgery Position Resident in Surgery Department Surgery Location Meander Medical Center City Amersfoort Country The Netherlands Quote “…”

MAIN PAPER Timmers TK, van der Ven DJ, de Vries LS, van Olden GD. Functional outcome after tibial plateau fracture osteosynthesis: a mean follow-up of 6 years. Knee. 2014 Dec;21(6):1210-5. PubMed PMID: 25311514.

2011 Name Jaap Trappenburg PhD defense April 5th, 2011 PhD team Schrijvers, Lameris, Verheij, Monninkhof Speciality Epidemiology of Chronic Disease and Self-management Position Assistant Professor Department Nursing Science, Julius Center for Healt Sciences and Primary Care Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “Science is organized knowledge, wisdom is organized life “ MAIN PAPER Trappenburg JC, Monninkhof EM, Bourbeau J, Troosters T, Schrijvers AJ, Verheij TJ, Lammers JW. Effect of an action plan with ongoing support by a case manager on exacerbation-related outcome in patients with COPD: a multicentre randomised controlled trial.

Thorax. 2011 Nov;66(11):977-84. PubMed PMID: 21785156.

198 20 years Julius Center; 1996-2017

2011 Name Ingrid den Uijl PhD defense March 22nd, 2011 PhD team Grobbee, Biesma, Fischer Speciality Lecturer Animal Health Surveillance Position Lecturer Department Epidemiology and Public Health University of Surrey Location City Guildford Country United Kingdom Quote “When you think small nothing happens, when you think big small things happen, when you dream…the sky is the limit“ MAIN PAPER Scherpenzeel CG, den Uijl IE, van Schaik G, Olde Riekerink RG, Keurentjes JM, Lam TJ. Evaluation of the use of dry cow antibiotics in low somatic cell count cows. J Dairy Sci. 2014;97(6):3606-14.

PubMed PMID: 24746132.

2011 Name Stephanie van de Ven PhD defense March 3rd, 2011 Mali, Luijten, Wiethoff, Elias PhD team Clinical Epidemiology Speciality Position Senior Research Scientist Department Canary Center Stanford for Cancer Early Detection Location Stanford, CA City Country United States of America Quote “A candle loses nothing by lighting another candle” MAIN PAPER van de Ven S, Wiethoff A, Nielsen T, Brendel B, van der Voort M, Nachabe R,et al. A novel fluorescent imaging agent for diffuse optical tomography of the breast: first clinical experience in patients. Mol Imaging Biol. 2010 Jun;12(3):343-8. PubMed PMID: 19798535;

20 years Julius Center; 1996-2017 199

2011 Name Arjan van Zuilen PhD defense October 27th, 2011 PhD team Verhaar, Wetzels, Bots, Blankestijn Speciality Nephrology Position Internist-Nephrologist Department Nephrology and Hypertension Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “...”

MAIN PAPER van Zuilen AD, Bots ML, Dulger A, van der Tweel I, van Buren M, Ten Dam MA, et al. Multifactorial intervention with nurse practitioners does not change cardiovascular outcomes in patients with chronic kidney disease. Kidney Int. 2012 Sep;82(6):710-7. PubMed PMID: 22739979.

2011 Name Moniek Zuurbier PhD defense April 5th, 2011 PhD team Brunekreef, Hoek Speciality Environmental Health Epidemiology Position Senior Researcher Department Location Public Health Services Gelderland Midden City Arnhem Country the Netherlands Quote “…”

MAIN PAPER van Loenhout JA, le Grand A, Duijm F, Greven F, Vink NM, Hoek G, Zuurbier M. The effect of high indoor temperatures on selfperceived health of elderly persons. Environ Res. 2016 Apr;146:27-34. PubMed PMID: 26710340.

200 20 years Julius Center; 1996-2017

2011 Name Dorien Zwart PhD defense June 28th, 2011 PhD team Verheij, Kalkman, van rensen Speciality General Practice General Practitioner & Assistant Professor Position Department General Practice, Julius Center for Health Sciences and Primary Care University Medical Center Utrecht Location City Utrecht The Netherlands Country Quote “…”

MAIN PAPER Verbakel NJ, Langelaan M, Verheij TJ, Wagner C, Zwart DL. Effects of patient safety culture interventions on incident reporting in general practice: a cluster randomised trial. Br J Gen Pract. 2015 May;65(634):e319-29. PubMed PMID: 25918337.

20 years Julius Center; 1996-2017 201

Class of

2012

2012 Name Mark Aarts PhD defense February 3rd, 2012 PhD team Grolman, van der Heijden, Rovers Speciality Ear, Nose and Throat Medicine Ear, Nose and Throat Surgeon Position Department Ear, Nose and Throat Medicine Jeroen Bosch Hospital Location ‘s Hertogenbosch City Country The Netherlands Quote “…”

MAIN PAPER Aarts MC, van der Heijden GJ, Rovers MM, Grolman W. Remarkable differences between three evidence-based guidelines on management of obstructive sleep apnea-hypopnea syndrome.

Laryngoscope. 2013 Jan;123(1):283-91. PubMed PMID: 22990949.

2012 Name Annet van Abeelen PhD defense June 15th, 2012 PhD team Bossuyt, Grobbee, Uiterwaal, Roseboom Clinical Epidemiology Speciality Position Senior policy advisor managed entry agreements for pharmaceuticals Department Directorate of Pharmaceutical Affairs and Medical Technology Location Ministry of Health, Welfare and Sports The Hague City The Netherlands Country Quote Senior policy advisor managed entry agreements for MAIN PAPER van Abeelen AF, Elias SG, Bossuyt PM, Grobbee DE, van der Schouw YT, Roseboom TJ, Uiterwaal CS. Cardiovascular consequences of famine in the young. Eur Heart J. 2012 Feb;33(4):538-45. PubMed PMID: 21868476.

20 years Julius Center; 1996-2017 205

2012 Name Frederieke van der Baan PhD defense June 28th, 2012 Grobbee, Egberts, Klungel, Knol PhD team Speciality Epidemiology of Cancer Position Assistant Professor Department Clinical Epidemiology, Julius Center for Health Sciences and Primary Care Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “Enjoy the little things in life because one day you`ll look back and realize they were the big things“ MAIN PAPER Ovarian Cancer Association Consortium, Breast Cancer Association Consortium, and Consortium of Modifiers of BRCA1 and BRCA2., Hollestelle A, van der Baan FH, et al. No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer. Gynecol Oncol.

2016 May;141(2):386-401. PubMed PMID:25940428.

2012 Name Jeroen Becker PhD defense March 20th, 2012 PhD team Visser, Moons, Kwee, Amer-Wahlin Speciality Gynaecology Position Gynaecologist Department Obstetrics and Gynaecology Location St. Antonius Hospital City Nieuwegein Country The Netherlands Quote “…”

MAIN PAPER Becker JH, van Rijswijk J, Versteijnen B, Evers AC, van den Akker ES, van Beek E, et al. Is intrapartum fever associated with ST-waveform changes of the fetal electrocardiogram? A retrospective cohort study. BJOG. 2012 Oct;119(11):1410-6. PubMed PMID: 22827811.

206 20 years Julius Center; 1996-2017

2012 Name Marga Bekkers PhD defense May 15th, 2012 PhD team Brunekreef, Wijga Speciality Environmental Health Epidemiology Position Epidemiologist Department Coördinatiecentrum Expertise Arbeidsomstandigheden & Gezondheid Ministry of Defense Location City Doorn The Netherlands Country Quote “…”

MAIN PAPER Bekkers MB, Aalberse RC, Gehring U, Kerkhof M, Koppelman GH, de Jongste JC,et al. Hen’s egg, not cow’s milk, sensitization in infancy is associated with asthma: 10-year follow-up of the PIAMA birth cohort. J Allergy Clin Immunol. 2013 Dec;132(6):1427-8. PubMed PMID: 24131824.

2012 Remy Bemelmans Name PhD defense June 13th, 2012 PhD team Visseren, van der Graaf, Spiering, Wassink Vascular Medicine Speciality Position Internist-Vascular Medicine Department Internal Medicine and Gastroenterology Gelderse Vallei Hospital Location City Ede Country The Netherlands Quote “…”

MAIN PAPER Bemelmans RH, Coll B, Faber DR, Westerink J, Blommaert PP, Spiering W,Visseren FL. Vascular and metabolic effects of 12 days intensive walking to Santiago de Compostela. Atherosclerosis. 2010 Oct;212(2):621-7. PubMed PMID: 20598693.

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2012 Name Sjoukje van der Bij PhD defense December 6th, 2012 PhD team Moons, de Mol, Koffijberg, Vermeulen Speciality Data Scientist Position Senior Researcher Department Research and Development Location Functiewaardering Gezondheidszorg (FWG) City Utrecht Country The Netherlands Quote “Als je het niet kan oplossen, is het geen probleem” MAIN PAPER Van der Bij S, Vermeulen RC, Portengen L, Moons KG, Koffijberg H. Expected number of asbestos-related lung cancers in the Netherlands in the next two decades: a comparison of methods. Occup Environ Med. 2016 May;73(5):342-9. PubMed PMID: 26858099.

2012 Name Hanna Boogaard PhD defense October 24th, 2012, PhD team Brunekreef, Hoek Speciality Epidemiology Position Consulting Senior Scientist Department Location Health Effects Institute City Boston Country United States of America Quote “...”

MAIN PAPER Boogaard H, Fischer PH, Janssen NA, Kos GP, Weijers EP, Cassee FR, et al. Respiratory effects of a reduction in outdoor air pollution concentrations. Epidemiology. 2013 Sep;24(5):753-61. PubMed PMID: 23873073.

208 20 years Julius Center; 1996-2017

2012 Name Chantal Boonacker PhD defense April 24th, 2012 PhD team Hoes, Schilder, Rovers Speciality Clinical Epidemiology Assistant Professor Position Department Clinical Epidemiology, Julius Center for Health Sciences and Primary Care University Medical Center Utrecht Location City Utrecht The Netherlands Country Quote “…”

MAIN PAPER Boonacker CW, Hoes AW, van Liere-Visser K, Schilder AG, Rovers MM. A comparison of subgroup analyses in grant applications and publications. Am J Epidemiol. 2011 Jul 15;174(2):219-25. PubMed PMID: 21597099.

2012 Name Walter Bouwmeester PhD defense July 2nd, 2012 PhD team Moons, Twisk, Vergouwe Speciality Epidemiology Senior Research Consultant Position Department Location Pharmerit International City Rotterdam Country The Netherlands Quote “…”

MAIN PAPER Bouwmeester W, Moons KG, Kappen TH, van Klei WA, Twisk JW, Eijkemans MJ, Vergouwe Y. Internal validation of risk models in clustered data: a comparison of bootstrap schemes. Am J Epidemiol. 2013 Jun 1;177(11):1209-17. PubMed PMID: 23660796.

20 years Julius Center; 1996-2017 209

2012 Judith Brand Name PhD defense October 24th, 2012 PhD team Van der Schouw Speciality Epidemiology of Breast Cancer and Cardio­metabolic Disorders Position Postdoctoral Researcher Department MRC Integrative Epidemiology Unit Location Bristol University City Bristol Country United Kingdom Quote “As our world continues to generate unimaginable amounts of data, more data lead to more correlations, and more correlations can lead to more discoveries.” - Hans Rosling MAIN PAPER Brand JS, van der Schouw YT, Onland-Moret NC, Sharp SJ, Ong KK, Khaw KT, et al. InterAct Consortium. Age at menopause, reproductive life span, and type 2 diabetes risk: results from the EPIC-InterAct study. Diabetes Care. 2013 Apr;36(4):1012-9. PubMed PMID: 23230098.

2012 Name Sanne Dorhout Mees PhD defense June 7th, 2012 PhD team Rinkel, Algra, van den Bergh Speciality Neurology Position Neurologist Department Neurology and Neurosurgery Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “…”

MAIN PAPER Dorhout Mees SM, Algra A, Vandertop WP, van Kooten F, Kuijsten HAJM, Boiten J, et al, on behalf of the MASH-2 Study Group.

Magnesium for aneurysmal subarachnoid haemorrhage (MASH-2): a randomised placebo-controlled trial. Lancet 2012;380:44-9.

PubMed PMID: 22633825.

210 20 years Julius Center; 1996-2017

2012 Name Dietje Fransen van de Putte PhD defense November 8th, 2012 PhD team Biesma, Mauser-Bunschoten, Fischer Speciality Clinical Genetics Clinical Geneticist Position Department Medical Genetics University Medical Center Utrecht Location City Utrecht Country The Netherlands Quote “It takes both rain and sunshine to create a rainbow” MAIN PAPER Fransen van de Putte DE, Fischer K, Makris M, Tait RC, Chowdary P, Collins PW, et al. Unfavourable cardiovascular disease risk profiles in a cohort of Dutch and British haemophilia patients. Thromb Haemost. 2013 Jan;109(1):16-23. PubMed PMID: 23138324.

2012 Name Anne Grool PhD defense April 19th, 2012 PhD team Van der Graaf, Mali, Geerlings Speciality Radiology Resident in Radiology Position Department Diagnostic Radiology Location Gelre Hospital City Apeldoorn Country The Netherlands Quote “Not everything that can be counted counts, and not every that counts can be counted” MAIN PAPER Grool AM, Gerritsen L, Zuithoff NP, Mali WP, van der Graaf Y, Geerlings MI. Lacunar infarcts in deep white matter are associated with higher and more fluctuating depressive symptoms during three years follow-up. Biol Psychiatry. 2013 Jan 15;73(2):169-76. PubMed PMID: 23079234.

20 years Julius Center; 1996-2017 211

2012 Name Anne van der Gugten PhD defense November 29th, 2012 Van der Ent, Uiterwaal PhD team Speciality Pediatric Medicine Position Resident in Pediatric Medicine Department Pediatric Medicine Location Unversity Medical Center Utrecht City Utrecht Country The Netherlands Quote “…”

MAIN PAPER van der Gugten AC, Uiterwaal CS, Verheij TJ, van der Ent CK. E-health and consultation rates for respiratory illnesses in infants: a randomised clinical trial in primary care. Br J Gen Pract. 2015 Feb;65(631):e61-8. PubMed PMID: 25624309.

2012 Name Susan Hahné PhD defense December 18th, 2012 PhD team Coutinho, Boot Speciality Public Health Position Head of Department of Early Warning and Surveillance Department Centre for Infectious Disease Control Location National Institute for Public Health and the Environment (RIVM) City Bilthoven Country The Netherlands Quote “Selective hepatitis B virus vaccination has reduced hepatitis B virus transmission in the Netherlands“ MAIN PAPER Hahné SJ, Veldhuijzen IK, Wiessing L, Lim TA, Salminen M, Laar Mv. Infection with hepatitis B and C virus in Europe: a systematic review of prevalence and cost-effectiveness of screening. BMC Infect Dis. 2013 Apr 18;13:181. PubMed PMID: 23597411; 212 20 years Julius Center; 1996-2017

2012 Name Claire den Hoedt PhD defense November 22th, 2012 PhD team Verhaar, Bots, van den Dorpel, Grooteman Speciality Internal Medicine, Nephrology Resident in Internal Medicine Position Department Internal Medicine Erasmus Medical Center Location City Rotterdam Country The Netherlands Quote “Dialysis patients should be given ‘bitterballen’ instead of phosphorbinders” MAIN PAPER den Hoedt CH, Bots ML, Grooteman MP, van der Weerd NC, Penne EL, Mazairac AH, et al. CONTRAST Investigators.. Clinical predictors of decline in nutritional parameters over time in ESRD. Clin J Am Soc Nephrol. 2014 Feb;9(2):318-25. PubMed PMID: 24458074.

2012 Name Wim van der Hoek PhD defense January 26th, 2012 PhD team Coutinho, Schneeberger Clinical Epidemiology Speciality Position Head of Department for Respiratory Infections Department Epidemiology & Surveillance of Infectious Diseases Location National Institute for Public Health and the Environment (RIVM) City Bilthoven The Netherlands Country Quote “People intuitively overestimate the risk of rare events and underestimate the risk of common events“ MAIN PAPER van der Hoek W, Versteeg B, Meekelenkamp JC, Renders NH, Leenders AC, Weers-Pothoff I, et al. Follow-up of 686 patients with acute Q fever and detection of chronic infection. Clin Infect Dis. 2011 Jun 15;52(12):1431-6. PubMed PMID: 21628483

20 years Julius Center; 1996-2017 213

2012 Sonja de Jong Name PhD defense October 12th, 2012 PhD team Van den Berg, Veldink, Fischer Speciality Neurology Position Neurologist Department Neurology Location St Jansdal Hospital City Harderwijk Country The Netherlands Quote “Bij twijfel, doen./when in doubt, do it.”

MAIN PAPER de Jong SW, Huisman MH, Sutedja NA, van der Kooi AJ, de Visser M, Schelhaas HJ, et al. Smoking, alcohol consumption, and the risk of amyotrophic lateral sclerosis: a population-based study. Am J Epidemiol. 2012 Aug 1;176(3):233-9. PubMed PMID: 22791740.

2012 Name Marijke Kars PhD defense April 24th, 2012 PhD team van Delden, Grypdonck Speciality Medical Ethics Position Assistant Professor of Medical Ethics Department Medical Humanities, Julius Center for Health Sciences and Primary Care Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “...”

MAIN PAPER Kars MC, Grypdonck MH, Beishuizen A, Meijer-van den Bergh EM, van Delden JJ.Factors influencing parental readiness to let their child with cancer die. Pediatr Blood Cancer. 2010 Jul 1;54(7):1000-8.

PubMed PMID: 20405517.

214 20 years Julius Center; 1996-2017

2012 Name Hans Kelder PhD defense June 26th, 2012 PhD team Hoes, Grobbee, Cramer Speciality Clinical Epidemiology Clinical Epidemiologist Position Department Cardiology St. Antonius Hospital Location City Nieuwegein Country The Netherlands Quote “…”

MAIN PAPER Kelder JC, Cramer MJ, van Wijngaarden J, van Tooren R, Mosterd A, Moons KG,et al. The diagnostic value of physical examination and additional testing in primary care patients with suspected heart failure. Circulation. 2011 Dec 20;124(25):2865-73. PubMed PMID: 22104551.

2012 Name Mariëtte Lokate PhD defense May 15th, 2012 PhD team Peeters, van Gils Speciality Infection Control Practitioner & Researcher Position Infection Control Practitioner & Researcher Department Medical Microbiology & Infection Prevention Location University Medical Center Groningen City Groningen Country The Netherlands “Negative results can also be good results“ Quote MAIN PAPER Lokate M, Peeters PH, Peelen LM, Haars G, Veldhuis WB, van Gils CH. Mammographic density and breast cancer risk: the role of the fat surrounding the fibroglandular tissue. Breast Cancer Res. 2011 Oct 26;13(5):R103. PubMed PMID: 22030015

20 years Julius Center; 1996-2017 215

2012 Name Janneke de Man-van Ginkel PhD defense August 30th, 2012 PhD team Schuurmans, Grobbee, Lindeman, Hafsteindottir Speciality Epidemiology of Rehabilitation and Recovery after Stroke Position Assistant Professor Department Nursing Science, Julius Center for Health Sciences and Primary Care Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “By conducting good research, I can provide proper care for many more patients than by delivering care myself “ MAIN PAPER de Man-van Ginkel JM, Hafsteinsdóttir TB, Lindeman E, Ettema RG, Grobbee DE, Schuurmans MJ. In-hospital risk prediction for post-stroke depression: development and validation of the Post-stroke Depression Prediction Scale. Stroke. 2013 Sep;44(9):2441-5. PubMed PMID: 23868275.

2012 Name Marianne Melsen PhD defense February 14th, 2012 PhD team Bonten, Rovers Speciality Medical Oncology Position Medical oncologist Department Internal Medicine Location St. Antonius Hospital City Utrecht Country The Netherlands Quote “Difficult roads often lead to beautiful destinations” MAIN PAPER Melsen WG, Rovers MM, Groenwold RH, Bergmans DC, Camus C, Bauer TT, et al. Attributable mortality of ventilator-associated pneumonia: a meta-analysis of individual patient data from randomised prevention studies. Lancet Infect Dis. 2013 Aug;13(8):665-71. PubMed PMID: 23622939.

216 20 years Julius Center; 1996-2017

2012 Name Yan Miao PhD defense May 21st, 2012 PhD team de Zeeuw, Grobbee, Lambers, Heerspink Speciality Project management Position Clinical Research and Development Lead (clinical trial physician) Department Clinical Research and Development Glaxo Smith Kline Location City Zeist The Netherlands Country Quote “Everyone has his own specific opportunity in life” MAIN PAPER Miao Y, Ottenbros SA, Laverman GD, Brenner BM, Cooper ME, Parving HH, et al. Effect of a reduction in uric acid on renal outcomes during losartan treatment: a post hoc analysis of the reduction of endpoints in non-insulin-dependent diabetes mellitus with the Angiotensin II Antagonist Losartan Trial. Hypertension.

2011 Jul;58(1):2-7. PubMed PMID: 21632472.

2012 Chong Guan Ng Name PhD defense December 11th, 2012 de Wit, Boks PhD team Speciality Psychiatry Associate Professor of Psychiatry Position Department Psychological Medicine University of Malaya Location Kuala Lumpur City Country Malaysia “Just live in and enjoy the present moment“ Quote MAIN PAPER Ng CG, Boks MP, Roes KC, Zainal NZ, Sulaiman AH, Tan SB, de Wit NJ. Rapid response to methylphenidate as an add-on therapy to mirtazapine in the treatment of major depressive disorder in terminally ill cancer patients: a four-week, randomized, doubleblinded, placebo-controlled study. Eur Neuropsychopharmacol.

2014 Apr;24(4):491-8. PubMed PMID: 24503279.

20 years Julius Center; 1996-2017 217

2012 Name Sunanto Ng PhD defense January 24th, 2012 PhD team Grobbee, Ottervanger, Soerianata Speciality Cardiology Position Clinical and Interventional Cardiologist Department Cardiology Location Faculty of Medicine, Location of Pelita Harapan City Banten Country Indonesia Quote “Virtue is more valuable than Location degree“ MAIN PAPER Ng S, Ottervanger JP, van ‘t Hof AW, de Boer MJ, Reiffers S, Dambrink JH, et al. Impact of ischemic time on post-infarction left ventricular function in ST-elevation myocardial infarction treated with primary percutaneous coronary intervention. Int J Cardiol. 2013 May 25;165(3):523-7. PubMed PMID: 22000421.

2012 Name Irene Oudejans- Mooijaart PhD defense May 10th, 2012 PhD team Hoes, Mosterd Speciality Geriatric Medicine Position Geriatrician Department Geriatric Medicine Location Medisch Spectrum Twente City Enschede Country The Netherlands Quote “…”

MAIN PAPER Oudejans I, Mosterd A, Bloemen JA, Valk MJ, van Velzen E, Wielders JP, et al. Clinical evaluation of geriatric outpatients with suspected heart failure: value of symptoms, signs, and additional tests. Eur J Heart Fail. 2011 May;13(5):518-27. PubMed PMID:21422000.

218 20 years Julius Center; 1996-2017

2012 Name Sanne Peters PhD defense October 2nd, 2012 PhD team Bots, Grobbee, den Ruijter Speciality Epidemiology Position Research Fellow Department The George Institute for Global Health Location University of Oxford City Oxford Country United Kingdom Quote “…”

MAIN PAPER Peters SA, den Ruijter HM, Grobbee DE, Bots ML. Results from a carotid intima-media thickness trial as a decision tool for launching a large-scale morbidity and mortality trial. Circ Cardiovasc Imaging.

2013 Jan 1;6(1):20-5. PubMed PMID: 23204038.

2012 Name Sharmini Selvarajah PhD defense November 22nd, 2012 PhD team Bots, van der Graaf Speciality Clinical Epidemiology Position Clinical Epidemiologist Department Location Sharmini Selvarajah Consulting City Petaling Jaya Country Malaysia Quote “…”

MAIN PAPER Selvarajah S, Kaur G, Haniff J, Cheong KC, Hiong TG, van der Graaf Y, Bots ML. Comparison of the Framingham Risk Score, SCORE and WHO/ISH cardiovascular risk prediction models in an Asian population. Int J Cardiol. 2014 Sep;176(1):211-8. PubMed PMID: 25070380.

20 years Julius Center; 1996-2017 219

2012 Gudrún Stefánsdottir Name PhD defense December 5th, 2012 PhD team Grobbee, Leufkens, Knol, de Bruin Speciality Strategic guidance and support for routine and ad hoc signal detection and management related activities.

Position Senior Manager Signal Management Department Safety Science, Global Pharmacovigilance Location Astellas Pharma City Leiden Country The Netherlands Quote “...”

MAIN PAPER A Business Intelligence Solution to Pharmacovigilance Signal Tracking and Management: One Mid-Size Pharma’s Experience.

Pharm Med (2015) 29:197–201

2012 Name Roderick Venekamp PhD defense June 7th, 2012 PhD team Bonten, Verheij, Sachs, Rovers Speciality General Practice Position General Practitioner & Assistant Professor Department General Practice, Julius Center for Health Sciences and Primary Care Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “...”

MAIN PAPER Venekamp RP, Thompson MJ, Rovers MM. Systemic corticosteroid therapy for acute sinusitis. JAMA. 2015 Mar 24-31;313(12):1258-9.

PubMed PMID: 25803348.

220 20 years Julius Center; 1996-2017

2012 Name Sandra Verhagen PhD defense September 11th, 2012 PhD team Visseren, van der Graaf, Vink, Wassink Speciality Psychiatry Position Resident in Psychiatry Department Mentrum Location Mentrum: institute for severe psychiatric disease City Amsterdam Country The Netherlands Quote “Where observation is concerned, chance only favors the prepared mind “ - Louis Pasteur MAIN PAPER Verhagen SN, Buijsrogge MP, Vink A, van Herwerden LA, van der Graaf Y, Visseren FL. Secretion of adipocytokines by perivascular adipose tissue near stenotic and non-stenotic coronary artery segments in patients undergoing CABG. Atherosclerosis. 2014 Mar;233(1):242-7. PubMed PMID: 24529151.

2012 Name Joris Vernooij PhD defense July 5th, 2012 PhD team Visseren, van der Graaf, Spiering Speciality Internal Medicine- Vascular Medicine Position Internist Department Location Chronic Fatigue Centre City Lelystad Country The Netherlands Quote “There is a crack in everything, that’s how the light gets in. - Leonard Cohen MAIN PAPER Vernooij JW, Kaasjager HA, van der Graaf Y, Wierdsma J, Grandjean HM, Hovens MM, et al. SMARTStudy Group. Internet based vascular risk factor management for patients with clinically manifest vascular disease: randomised controlled trial. BMJ. 2012 Jun 12;344:e3750. PubMed PMID: 22692651.

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2012 Astrid Vollebregt Name PhD defense November 28th, 2012 PhD team Van der Vaart, Fischer Speciality Gynaecology Position Gynaecologist Department Obstetrics and Gynaecology Location Spaarne Gasthuis City Haarlem Country The Netherlands Quote “…”

MAIN PAPER Vollebregt A, Fischer K, Gietelink D, van der Vaart CH. Primary surgical repair of anterior vaginal prolapse: a randomised trial comparing anatomical and functional outcome between anterior colporrhaphy and trocar-guided transobturator anterior mesh.

BJOG. 2011 Nov;118(12):1518-27. PubMed PMID: 21864325.

2012 Name Grace Wangge PhD defense November 5th, 2012 PhD team de Boer, Hoes, Knol, Klungel Speciality Pharmaco-epidemiology Position Senior Consultant Department Epidemiology and Statistics, Department of Community Medicine, Faculty of Medicine Location University of Indonesia & HEMISPHERE City Jakarta Country Indonesia Quote “…”

MAIN PAPER Wangge G, Schneeweiss S, Glynn RJ, Gagne JJ. Developing alerting thresholds for prospective drug safety monitoring. Pharmacoepidemiol Drug Saf. 2016 Jul;25(7):755-62. PubMed PMID: 26596260.

222 20 years Julius Center; 1996-2017

2012 Name Neelke van der Weerd PhD defense September 5th, 2012 PhD team Ter Wee, Bots, Grooteman, Blankestijn Speciality Nephrology Position Internist-Nephrologist Department Nephrology Location Academic Medical Center - University of Amsterdam City Amsterdam Country The Netherlands Quote “Ik heb de pest aan mensen die een proefschrift schrijven alleen om de titel. Als je wat te vertellen hebt, kun je dat ook wel zonder proefschrift” - Het Bureau van J.J. Voskuil MAIN PAPER van der Weerd NC, Grooteman MP, Bots ML, van den Dorpel MA, den Hoedt CH, Mazairac AH, et al. CONTRAST Investigators.

Hepcidin-25 is related to cardiovascular events in chronic haemodialysis patients. Nephrol Dial Transplant. 2013 Dec;28(12):3062-71. PubMed PMID: 23147161.

2012 Jan Westerink Name PhD defense June 6th, 2012 PhD team Visseren, van der Graaf, Spiering Vascular Medicine Speciality Position Internist Department Vascular Medicine University Medical Center Utrecht Location City Utrecht Country The Netherlands “Je gaat niet zo maar dood” Quote MAIN PAPER Westerink J, Deanfield JE, Imholz BP, Spiering W, Basart DC, Coll B, Kastelein JJ, Visseren FL. High-dose statin monotherapy versus low-dose statin/ezetimibe combination on fasting and postprandial lipids and endothelial function in obese patients with the metabolic syndrome: The PANACEA study. Atherosclerosis. 2013 Mar;227(1):118-24. PubMed PMID: 23261174.

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2012 Name Carla Zomer PhD defense June 7th, 2012 PhD team Grobbee, Mulder, Vaartjes Speciality Cardiology Resident in Cardiology Position Department Cardiology St. Antonius Hospital Location City Nieuwegein Country The Netherlands Quote “...”

MAIN PAPER Zomer AC, Ionescu-Ittu R, Vaartjes I, Pilote L, Mackie AS, Therrien J, et al. Sex differences in hospital mortality in adults with congenital heart disease: the impact of reproductive health. J Am Coll Cardiol.

2013 Jul 2;62(1):58-67. PubMed PMID: 23644083.

2012 Name Peter Zuithoff PhD defense April 17th, 2012 PhD team Moons, Geerlings, Vergouwe Biostatistics & Research Support Speciality Assistant Professor Position Department Biostatistics, Julius Center for Health Sciences and Primary Care University Medical Center Utrecht Location City Utrecht The Netherlands Country Quote “In theory, there is no difference between theory and practice. But, in practice, there is” - Attributed to Jan L. A. van de Snepscheut MAIN PAPER Bouwmeester W, Zuithoff NP, Mallett S, Geerlings MI, Vergouwe Y, Steyerberg EW, et al. Reporting and methods in clinical prediction research: a systematic review. PLoS Med. 2012;9(5):1-12 PubMed PMID: 22629234.

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Class of

2013

2013 Name Maaike van den Aardweg PhD defense December 20th, 2013 PhD team Schilder, Rovers Speciality Ear, Nose, and Throat Medicine Resident in Ear, Nose, and Throat Medicine Position Department Otorhinolaryngology University Medical Center Utrecht Location City Utrecht Country The Netherlands Quote “…”

MAIN PAPER van den Aardweg MT, Boonacker CW, Rovers MM, Hoes AW, Schilder AG. Effectiveness of adenoidectomy in children with recurrent upper respiratory tract infections: open randomised controlled trial.

BMJ. 2011 Sep 6;343:d5154. PubMed PMID: 21896611

2013 Name Sefanja Achterberg PhD defense February 1st, 2013 PhD team Algra, Kappelle Neurology – intensive care Speciality Neurologist, resident in intensive care medicine Position Department Intensive Care Location University Medical Center Utrecht City Utrecht Country The Netherlands “Don’t dream your life, live your dream“ Quote MAIN PAPER Achterberg S, Kappelle LJ, de Bakker PI, Traylor M, Algra A; SMART Study Group and the METASTROKE Consortium. No Additional Prognostic Value of Genetic Information in the Prediction of Vascular Events after Cerebral Ischemia of Arterial Origin: The PROMISe Study. PLoS One. 2015 Apr 23;10(4):e0119203. PubMed PMID: 25906364.

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2013 Mireille Baart Name PhD defense June 25th, 2013 Moons, Vergouwe, de Kort PhD team Speciality Epidemiology in public health, nutrition and sports Position Scientist Department Clinical Chemistry and Haematology Laboratory Location Gelderse Vallei Hospital City Ede Country The Netherlands Quote “Balanced training and optimal nutrition are the keys for optimal performance in sport and care.”

MAIN PAPER Baart AM, de Kort WL, Atsma F, Moons KG, Vergouwe Y. Development and validation of a prediction model for low hemoglobin deferral in a large cohort of whole blood donors. Transfusion. 2012 Dec;52(12):2559-69. PubMed PMID: 22519683.

2013 Name Rosemarie de la Cruz - Bernabe PhD defense April 23rd, 2013 PhD team Van Delden, Raaijmakers, van Thiel Speciality Medical Research Ethics Position Scientia Marie Curie Postdoctoral Fellow Department Center for Medical Ethics at the Institute of Health and Society, Faculty of Medicine Location University of Oslo City Oslo Country Norway Quote “The universal right to health can only be attained when justice is defined with compassion.” - Rose Bernabe MAIN PAPER Bernabe RD, van Thiel GJ, Breekveldt NS, van Delden JJ. Drug regulators and ethics: which GCP issues are also ethical issues?

Drug Discov Today. 2016 Feb;21(2):217-24. PubMed PMID: 26610417.

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2013 Name Nienke Bleijenberg PhD defense October 17th, 2013 PhD team Schuurmans, de Wit, van Dam Speciality Nursing Sciences of the elderly in primary care Assistant Professor Position Department Nursing Sciences, Julius Center for Health Sciences and Primary Care University Medical Center Utrecht Location City Utrecht The Netherlands Country Quote “The only way to do great work is to love what you do” - Steve Jobs MAIN PAPER Bleijenberg N, Drubbel I, Schuurmans MJ, Dam HT, Zuithoff NP, Numans ME, de Wit NJ. Effectiveness of a Proactive Primary Care Program on Preserving Daily Functioning of Older People: A Cluster Randomized Controlled Trial. J Am Geriatr Soc. 2016 Sep;64(9):177988. PubMed PMID: 27459236.

2013 Name Ruud Boessen PhD defense March 28th, 2013 Grobbee, Roes, Knol, Groenwold PhD team Data Scientist Speciality Senior policy advisor Position Department Ministry of Finance Location City Rotterdam Country The Netherlands Quote “...”

MAIN PAPER Boessen R, Heerspink HJ, De Zeeuw D, Grobbee DE, Groenwold RH, Roes KC. Improving clinical trial efficiency by biomarker-guided patient selection. Trials. 2014 Apr 2;15:103. PubMed PMID: 24690215;

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2013 Name Nanne Bos PhD defense June 24th, 2013 Schrijvers, Sturms, van Stel PhD team Speciality Epidemiology Position Senior researcher Department Location Netherlands Institute for Health Services Research, Utrecht (NIVEL) City Utrecht Country The Netherlands Quote “...”

MAIN PAPER Bos N, Seccombe IJ, Sturms LM, Stellato R, Schrijvers AJ, van Stel HF. A comparison of the quality of care in accident and emergency departments in England and the Netherlands as experienced by patients. Health Expect. 2016 Jun;19(3):773-84.

2013 Name Elemi Breetvelt PhD defense June 3rd, 2013 PhD team Kahn, Grobbee, Boks, Aukes Speciality Pediatric Psychiatry Position Child psychiatrist and epidemiologist Department The Dalglish Family 22q Clinic Location Toronto General Hospital City Toronto Country Canada Quote “ Bad luck and misfortune tend to cluster “ “Assumption is the mother of all f..k-ups “ - Siege 2 MAIN PAPER man JA, Breetvelt EJ, Duijff SN, et al.International Consortium on Brain and Behavior in 22q11.2 Deletion Syndrome.. Cognitive decline preceding the onset of psychosis in patients with 22q11.2 deletion syndrome. JAMA Psychiatry. 2015 Apr;72(4):377-85.

PubMed PMID: 25715178.

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2013 Name Patricia Bruijning-Verhagen PhD defense January 17th, 2013 PhD team Bonten, Quach Speciality Clinical Epidemiology Assistant Professor Position Department Infectious disease, Julius Center for Health Sciences and Primary Care University Medical Center Utrecht Location City Utrecht The Netherlands Country “Prevention is better than cure” Quote MAIN PAPER Bruijning-Verhagen P, Mangen MJ, Felderhof M, Hartwig NG, van Houten M, Winkel L, et al. Targeted rotavirus vaccination of high-risk infants; a low cost and highly cost-effective alternative to universal vaccination. BMC Med. 2013 Apr 26;11:112. PubMed PMID: 23622110.

2013 Gerdien Dalmeijer Name PhD defense June 11th, 2013 PhD team Van der Schouw, Beulens Clinical Epidemiology Speciality Position Assistant Professor Department Public Health, Julius Center for Health Sciences and Primary Care University Medical Center Utrecht Location City Utrecht The Netherlands Country Quote “...”

MAIN PAPER Wang X, Dalmeijer GW, den Ruijter HM, Anderson TJ, Britton AR, Dekker J,et al. Clustering of cardiovascular risk factors and carotid intima-media thickness: The USE-IMT study. PLoS One. 2017 Mar 21;12(3):e0173393. PubMed PMID: 28323823.

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2013 Name Thomas Debray PhD defense October 29th, 2013 Moons, Steyerberg, Koffijberg, Vergouwe PhD team Speciality Clinical Epidemiology Position Assistant Professor Department Clinical Epidemiology, Julius Center for Health Sciences and Primary Care Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “...”

MAIN PAPER Debray TP, Damen JA, Snell KI, Ensor J, Hooft L, Reitsma JB, Riley RD, Moons KG. A guide to systematic review and meta-analysis of prediction model performance. BMJ. 2017 Jan 5;356:i6460. PubMed PMID: 28057641.

2013 Name Lennie Derde PhD defense February 20th, 2013 PhD team Bonten Speciality Intensive Care, Infectious Diseases Position Consultant in intensive care, consultant in infectious diseases & Postdoctoral Researcher Department Intensive Care Center, Division Vital Functions & Julius Center for Health Sciences and Primary Care Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “…”

MAIN PAPER Derde LP, Cooper BS, Goossens H, Malhotra-Kumar S, Willems RJ, Gniadkowski M, et al. MOSAR WP3 Study Team. Interventions to reduce colonisation and transmission of antimicrobial-resistant bacteria in intensive care units: an interrupted time series study and cluster randomized trial. Lancet Infect Dis. 2014 Jan;14(1):31-9.

PubMed PMID: 24161233.

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2013 Name Suzanne van Dieren PhD defense May 16th, 2013 PhD team Van der Schouw, Beulens, Peelen Speciality Epidemiology Senior Clinical Epidemiologist Position Department Surgery Location Academic Medical Center - University of Amsterdam City Amsterdam The Netherlands Country Quote “All models are wrong, but some are useful” - G.E.P. Box MAIN PAPER Vennix S, van Dieren S, Opmeer BC, Lange JF, Bemelman WA. Cost analysis of laparoscopic lavage compared with sigmoid resection for perforated diverticulitis in the Ladies trial. Br J Surg. 2017 Jan;104(1):62-68. PubMed PMID: 28000941.

2013 Name Madeleine Dolleman PhD defense December 17th, 2013 PhD team Broekmans, van der Schouw, Mol, van Disseldorp Obstetrics and Gynaecology Speciality Resident in Obstetrics and Gynaecology Position Department Obstetrics and Gynaecology University Medical Center Utrecht Location City Utrecht Country The Netherlands Quote “Life can only be understood backwards; but it must be lived forwards” MAIN PAPER Dólleman M, Verschuren WM, Eijkemans MJ, Dollé ME, Jansen EH, Broekmans FJ, van der Schouw YT. Reproductive and lifestyle determinants of anti-Müllerian hormone in a large population-based study. J Clin Endocrinol Metab. 2013 May;98(5):2106-15.

PubMed PMID: 23533229.

20 years Julius Center; 1996-2017 235

2013 Jannick Dorresteijn Name PhD defense February 5th, 2013 PhD team Visseren, van der Graaf, Spiering Speciality Vascular Medicine Position Fellow Department Internal Medicine Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “The average patient does not exist“ MAIN PAPER Dorresteijn JA, Kaasenbrood L, Cook NR, van Kruijsdijk RC, van der Graaf Y, Visseren FL, Ridker PM. How to translate clinical trial results into gain in healthy life expectancy for individual patients. BMJ. 2016 Mar 30;352:i1548. PubMed PMID: 27029390.

2013 Name Corine den Engelsen PhD defense February 12th, 2013 PhD team Rutten, Gorter Speciality General Practice Position General Practitioner Department Location Huisartsenzorg IJsselstein, locatie ‘t Steyn City IJselstein Country The Netherlands Quote “We shall not cease from exploration And the end of all our exploring Will be to arrive where we started And know the place for the first time. - T.S. Eliot, Four Quartets, 1943 MAIN PAPER den Engelsen C, Gorter KJ, Salomé PL, Rutten GE. Development of metabolic syndrome components in adults with a healthy obese phenotype: a 3-year follow-up. Obesity (Silver Spring). 2013 May;21(5):1025-30. PubMed PMID: 23404911.

236 20 years Julius Center; 1996-2017

2013 Name Annemieke Evelein PhD defense January 31st, 2013 PhD team Grobbee, Visseren, Uiterwaal Speciality Pediatric Medicine Resident in Pediatric Medicine Position Department Pediatric Medicine Gelre Hospital Location City Apeldoorn Country The Netherlands Quote “...”

MAIN PAPER Evelein AM, Visseren FL, van der Ent CK, Grobbee DE, Uiterwaal CS. Allergies are associated with arterial changes in young children. Eur J Prev Cardiol. 2015 Nov;22(11):1480-7. PubMed PMID: 25301873.

2013 Name Margriet van der Heiden – van der Loo PhD defense February 14th, 2013 PhD team Peeters, Rutgers Speciality Epidemiology of the Late effects after childhood cancer Position Head Dutch Childhood Oncology Group LATER Department Dutch Childhood Oncology Group - Early Clinical Trial Consortium Location Dutch Childhood Oncology Group - Early Clinical Trial Consortium The Hague City Country The Netherlands “Samen bevlogen verder“ Quote MAIN PAPER van der Heiden-van der Loo M, Schaapveld M, Ho VK, Siesling S, Rutgers EJ, Peeters PH. Outcomes of a population-based series of early breast cancer patients with micrometastases and isolated tumour cells in axillary lymph nodes. Ann Oncol. 2013 Nov;24(11):2794-801. PubMed PMID: 23864096.

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2013 Hadassa Jochemsen Name PhD defense October 4th, 2013 PhD team Scheltens, van der Graaf, Muller, Geerlings Speciality General Practice Position Resident in General Practice Department Location City Veenendaal Country The Netherlands Quote “…”

MAIN PAPER Jochemsen HM, Muller M, Bots ML, Scheltens P, Vincken KL, Mali WP, et al.SMART Study Group. Arterial stiffness and progression of structural brain changes: The SMART-MR study. Neurology. 2015 Feb 3;84(5):448-55. PubMed PMID: 25552578.

2013 Name Danny Kanhai PhD defense March 19th, 2013 PhD team Visseren, Kappelle, Uiterwaal Speciality Paediatric Medicine Position Resident in Paediatric Medicine Department Paediatric Medicine Location University Medical Center Groningen City Groningen Country The Netherlands Quote “…”

MAIN PAPER Kanhai DA, Visseren FL, van der Graaf Y, Schoneveld AH, Catanzariti LM, Timmers L, et al. SMART Study Group. Microvesicle protein levels are associated with increased risk for future vascular events and mortality in patients with clinically manifest vascular disease.

Int J Cardiol. 2013 Oct 3;168(3):2358-63. PubMed PMID: 23484740.

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2013 Name Melvin Lafeber PhD defense December 11th, 2013 PhD team Grobbee, Visseren, Spiering Speciality Vascular Medicine Position Resident in Internal Medicine (Vascular Medicine and Clinical Pharmacology) Department Vascular Medicine University Medical Center Utrecht Location City Utrecht The Netherlands Country “The perfect is the enemy of the good “ Quote MAIN PAPER Lafeber M, Grobbee DE, Schrover IM, Thom S, Webster R, Rodgers A, et al. Comparison of a morning polypill, evening polypill and individual pills on LDL-cholesterol, ambulatory blood pressure and adherence in high-risk patients; a randomized crossover trial. Int J Cardiol. 2015 Feb 15;181:193-9. PubMed PMID: 25528311.

2013 Sanne Nijhof Name PhD defense December 6th, 2013 PhD team Kimpen, Bleijenberg, van der Putte, Uiterwaal Pediatric Medicine Speciality Position Pediatrician Department Pediatric Medicine Location Wilhelmina Children’s Hospital, University Medical Center Utrecht City Utrecht The Netherlands Country Quote “it is not the strongest of the species that survives, nor the most intelligent that survives. It is the one that is most adaptable to change” MAIN PAPER Nijhof SL, Bleijenberg G, Uiterwaal CS, Kimpen JL, van de Putte EM. Effectiveness of internet-based cognitive behavioural treatment for adolescents with chronic fatigue syndrome (FITNET): a randomised controlled trial. Lancet. 2012 Apr 14;379(9824):1412-8. PubMed PMID: 22385683.

20 years Julius Center; 1996-2017 239

2013 Name Marjolein den Ouden PhD defense March 5th, 2013 PhD team Van der Schouw, Schuurmans Speciality Epidemiology Position Senior Researcher & Teacher Department Center of Nursing Location University of Applied Sciences Saxion City Deventer and Enschede Country The Netherlands Quote “You are never too old to set another goal or to dream a new dream” MAIN PAPER den Ouden ME, Schuurmans MJ, Mueller-Schotte S, Brand JS, van der Schouw YT. Domains contributing to disability in activities of daily living. J Am Med Dir Assoc. 2013 Jan;14(1):18-24. PubMed PMID: 23043731.

2013 Name Michelle Putzeist PhD defense June 19th, 2013 PhD team Leufkens, Hoes, Mantel, Gispen-de Wied Speciality Pharmaceutical Sciences Position Pricing and Market Access Manager Department Location Novartis City Arnhem Country The Netherlands Quote “…”

MAIN PAPER Putzeist M, Mantel-Teeuwisse AK, Wied CC, Hoes AW, Leufkens HG, de Vrueh RL. Drug development for exceptionally rare metabolic diseases: challenging but not impossible. Orphanet J Rare Dis. 2013 Nov 15;8:179. PubMed PMID: 24237580

240 20 years Julius Center; 1996-2017

2013 Name Ewoud Schuit PhD defense March 25th, 2013 PhD team Moons, Mol, Kwee, Groenwold Speciality Clinical Epidemiology Assistant Professor Position Department Clinical Epidemiology, Julius Center for Health Sciences and Primary Care University Medical Center Utrecht Location City Utrecht The Netherlands Country Quote “The core of mans’ spirit comes from new experiences. “ – Jon Krakauer (author Into the Wild) MAIN PAPER Schuit E, Stock S, Rode L, Rouse DJ, Lim AC, Norman JE, et al. Global Obstetrics Network (GONet) collaboration. Effectiveness of progestogens to improve perinatal outcome in twin pregnancies: an individual participant data meta-analysis. BJOG. 2015 Jan;122(1):2737. PubMed PMID: 25145491.

2013 Name Carolien Sino PhD defense December 12th, 2013 Schuurmans, Egberts PhD team Nursing Sciences Speciality Director Nursing Institute Position Department University of Applied Sciences Utrecht Utrecht University Location City Utrecht Country The Netherlands “No hocus pocus, but focus focus… “ Quote MAIN PAPER Sino CG, Bouvy ML, Jansen PA, Schop IM, Egberts TC, Schuurmans MJ. Signs and symptoms indicative of potential adverse drug reactions in homecare patients. J Am Med Dir Assoc. 2013 Dec;14(12):920-5. PubMed PMID: 24286711.

20 years Julius Center; 1996-2017 241

2013 Sabrina Siregar Name PhD defense June 13th, 2013 Van Herwerden, van der Graaf, Groenwold PhD team Speciality Cardio Thoracic Surgery Position Resident in Cardio Thoracic Surgery Department Cardio Thoracic Surgery Location Leiden University Medical Center City Leiden Country The Netherlands Quote “The world is my country and science is my religion “ - C. Huygens MAIN PAPER Siregar S, Groenwold RH, de Mol BA, Speekenbrink RG, Versteegh MI, Brandon Bravo Bruinsma GJ, et al. Evaluation of cardiac surgery mortality rates: 30-day mortality or longer follow-up?

Eur J Cardiothorac Surg. 2013 Nov;44(5):875-83. PubMed PMID: 23471150.

2013 Name Erik Udo PhD defense October 3th, 2013 PhD team Moons, Doevendans, Zuithoff Speciality Cardiology Position Cardiologist Department Cardiology Location Maasstad and Ikazia hospital City Rotterdam Country The Netherlands Quote “…”

MAIN PAPER Udo EO, Zuithoff NP, van Hemel NM, de Cock CC, Hendriks T, Doevendans PA, et al. Incidence and predictors of short- and long-term complications in pacemaker therapy: the FOLLOWPACE study. Heart Rhythm. 2012 May;9(5):728-35. PubMed PMID: 22182495.

242 20 years Julius Center; 1996-2017

2013 Monique Vlak Name PhD defense September 21st, 2013 PhD team Rinkel, Algra Speciality Neurology Position Neurologist – Somnologist Department Neurology Location Medical Center Haaglanden City The Hague Country The Netherlands Quote “…”

MAIN PAPER Vlak MHM, Algra A, Brandenburg R, Rinkel GJE. Prevalence of unruptured intracranial aneurysms, with emphasis on sex, age, comorbidity, country, and time period: a systematic review and meta-analysis. Lancet Neurol 2011;10:626-636. PubMed PMID: 21641282.

2013 Name Marlies Voorhuis PhD defense Juni 28th, 2013 PhD team Broekmans, van der Schouw Speciality Obstetrics and Gynaecology Position Resident in Obstetrics and Gynaecology Department Obstetrics and Gynaecology Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “Pick your battles big enough to matter, small enough to win (Jonathan Kozol)“ MAIN PAPER Voorhuis M, Broekmans FJ, Fauser BC, Onland-Moret NC, van der Schouw YT. Genes involved in initial follicle recruitment may be associated with age at menopause. J Clin Endocrinol Metab. 2011 Mar;96(3):E473-9. PubMed PMID: 21193543.

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2013 Name Dagmar Vos PhD defense September 17th, 2013 PhD team Van der Werken, van der Graaf Speciality Surgery Position Surgeon Department General and Trauma Surgery Location Amphia Hospital City Breda Country The Netherlands Quote “…”

MAIN PAPER Vos DI, Verhofstad MH, Hanson B, van der Graaf Y, van der Werken C. Clinical outcome of implant removal after fracture healing. Design of a prospective multicentre clinical cohort study. BMC Musculoskelet Disord. 2012 Aug 15;13:147. PubMed PMID: 22894749.

2013 Name Saskia van Vugt PhD defense June 10th, 2013 PhD team Verheij, Broekhuizen Speciality General Practice Position General Practitioner Department Location General Practice Huisarts Groen City Doorn Country The Netherlands Quote “…”

MAIN PAPER van Vugt SF, Verheij TJ, de Jong PA, Butler CC, Hood K, Coenen S, et al. GRACE Project Group. Diagnosing pneumonia in patients with acute cough: clinical judgment compared to chest radiography. Eur Respir J. 2013 Oct;42(4):1076-82. PubMed PMID: 23349450.

244 20 years Julius Center; 1996-2017

2013 Name Meng Wang PhD defense December 5th, 2013 Brunekreef, Hoek, Beelen PhD team Speciality Environmental Health Epidemiology Position Postdoctoral Fellow Department Environmental and Occupational Health Sciences Location University of Washington City Seatle Country United States of America Quote “…”

MAIN PAPER Wang M, Brunekreef B, Gehring U, Szpiro A, Hoek G, Beelen R. A New Technique for Evaluating Land-use Regression Models and Their Impact on Health Effect Estimates. Epidemiology. 2016 Jan;27(1):51-6. PubMed PMID: 26426941.

2013 Name Paulien Wermeling PhD defense June 4th, 2013 PhD team Rutten, Beulens, Gorter Speciality Epidemiology of Alzheimer’s disease and aging Position Epidemiologist Department Janssen Prevention Center, Janssen Vaccines and Prevention BV Location Janssen Pharmaceutical Companies from Jansen and Jansen City Leiden Country The Netherlands Quote “Always stay positive“ MAIN PAPER Wermeling PR, Gorter KJ, Stellato RK, de Wit GA, Beulens JW, Rutten GE. Effectiveness and cost-effectiveness of 3-monthly versus 6-monthly monitoring of well-controlled type 2 diabetes patients: a pragmatic randomised controlled patient-preference equivalence trial in primary care (EFFIMODI study). Diabetes Obes Metab. 2014 Sep;16(9):841-9. PubMed PMID: 24635880.

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Class of

2014

2014 Name Arthur Adams PhD defense May 21st, 2014 PhD team Mali, Elias Speciality Radiology Resident in Radiology Position Department Radiology University Medical Center Utrecht Location City Utrecht Country The Netherlands Quote “…”

MAIN PAPER Adams A, van Brussel AS, Vermeulen JF, Mali WP, van der Wall E, van Diest PJ, et al The potential of hypoxia markers as target for breast molecular imaging--a systematic review and meta-analysis of human marker expression. BMC Cancer. 2013 Nov 10;13:538. doi: 10.1186/1471-2407-13-538. Review. PubMed PMID: 24206539; PubMed Central PMCID: PMC3903452.

2014 Name Mohammed Sanni Ali PhD defense October 1st, 2014 De Boer, Hoes, Klungel, Groenwold PhD team Device and Pharmacoepidemiology Speciality Senior Research Associate Position Department Nuffield Department of Orthopaedics, Rheuma­ tology, Musculoskeletal Sciences, Center for Statistics in Medicine University of Oxford Location City Oxford Country United Kingdom Quote “…”

MAIN PAPER Ali MS, Groenwold RH, Belitser SV, Souverein PC, Martín E, Gatto NM, et al. Methodological comparison of marginal structural model, time-varying Cox regression, and propensity score methods: the example of antidepressant use and the risk of hip fracture.

Pharmacoepidemiol Drug Saf. 2016 Mar;25 Suppl 1:114-21.

PubMed PMID: 27038357.

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2014 Name Loes Bertens PhD defense March 11th, 2013 PhD team Hoes, Moons, Rutten, Reitsma Speciality Clinical Epidemiology Postdoctoral Researcher Position Department Obstetrics and Gynaecology Location Erasmus Medical Center City Rotterdam Country The Netherlands Quote “...”

MAIN PAPER Bertens LC, Broekhuizen BD, Naaktgeboren CA, Rutten FH, Hoes AW, van Mourik Y, et al. Use of expert panels to define the reference standard in diagnostic research: a systematic review of published methods and reporting. PLoS Med. 2013 Oct;10(10):e1001531.

PubMed PMID: 24143138

2014 Name Arnold Bitterman PhD defense December 16th, 2014 PhD team Grolman, van der Heijden Speciality Ear, Nose, and Throat medicine Position Consultant Pediatric ENT-surgeon Department Pediatric Otorhinolaryngology Location Royal Hospital for Sick Children City Glasgow Country United Kingdom Quote “...”

MAIN PAPER Bittermann AJ, van der Heijden GJ, Wegner I, Trabalzini F, Grolman W; European Academy of Otology and Neuro-Otology. Clinical practice guidelines on the management of patients with common otologic pathology toward European consensus: outline of approach. Otol Neurotol. 2013 Oct;34(8):1367-71. PubMed PMID: 24005174.

250 20 years Julius Center; 1996-2017

2014 Name Marieke Braem PhD defense January 7th, 2014 PhD team Peeters, Onland-Moret, Schouten Speciality Manager Analysis and Advice Position Manager Department Division Damage & Income Achmea (Health Care Insurrance company) Location City Apeldoorn Country The Netherlands Quote “An idea not coupled with action will never get any bigger than the brain cell it occupied. “ MAIN PAPER Braem MG, Onland-Moret NC, van den Brandt PA, Goldbohm RA, Peeters PH,Kruitwagen RF, Schouten LJ. Reproductive and hormonal factors in association with ovarian cancer in the Netherlands cohort study. Am J Epidemiol. 2010 Nov 15;172(10):1181-9.

PubMed PMID: 20861144;

2014 Name Vincent Busch PhD defense May 20th, 2014 Schrijvers, van Yperen, de Leeuw PhD team Health Behavior Speciality Senior Researcher Position Department Epdemiology, Health Promotion and Health Care Innovation Public Health Service Amsterdam (GGD) Location City Amsterdam The Netherlands Country Quote “Yes, I’m a doctor. Just not the kind that cures people.“ MAIN PAPER Busch V, de Leeuw JR, de Harder A, Schrijvers AJ. Changing multiple adolescent health behaviors through school-based interventions: a review of the literature. J Sch Health. 2013 Jul;83(7):514-23. PubMed PMID: 23782095.

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2014 Thijs van Dongen Name PhD defense May 23rd, 2014 PhD team Schilder, van der Heijden, Venekamp Speciality General Practice Position Resident in General Practice & Postdoctoral Researcher Department SBOH & General Practice, Julius Center for Health Sciences and Primary Care Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “...”

MAIN PAPER van Dongen TM, van der Heijden GJ, Venekamp RP, Rovers MM, Schilder AG. A trial of treatment for acute otorrhea in children with tympanostomy tubes. N Engl J Med. 2014 Feb 20;370(8):723-33.

PubMed PMID: 24552319.

2014 Name Irene Drubbel PhD defense January 14th, 2014 PhD team de Wit, Schuurmans, Numans Speciality General Practice Position General Practitioner Department Location General Practice City Houten Country The Netherlands Quote “…”

MAIN PAPER Drubbel I, Bleijenberg N, Kranenburg G, Eijkemans RJ, Schuurmans MJ, de Wit NJ, Numans ME. Identifying frailty: do the Frailty Index and Groningen Frailty Indicator cover different clinical perspectives? a cross-sectional study. BMC Fam Pract. 2013 May 21;14:64.

PubMed PMID: 23692735

252 20 years Julius Center; 1996-2017

2014 Name Jacobien Eising PhD defense August 28th, 2014 PhD team Van der Ent, Uiterwaal Speciality Pediatric Medicine Resident in Pediatric Medicine Position Department Pediatric Medicine Leiden University Medical Center Location City Leiden Country The Netherlands Quote “…”

MAIN PAPER Eising JB, van der Ent CK, Evelein AM, Uiterwaal CS. The association between lung function and arterial stiffness in young childhood.

Eur Respir J. 2014 Aug;44(2):530-2. PubMed PMID: 24833767.

2014 Name Remko Enserink PhD defense December 10th, 2014 PhD team Smit, Bonten, van Pelt Public Health Speciality US Medical Affairs Manager Position Department Location Echosens North America City Waltham Country United States of America “Google is not a synonym for research” Quote MAIN PAPER Enserink R, Lugnér A, Suijkerbuijk A, Bruijning-Verhagen P, Smit HA, van Pelt W. Gastrointestinal and respiratory illness in children that do and do not attend child day care centers: a cost-of-illness study.

PLoS One. 2014 Aug 20;9(8):e104940. PubMed PMID: 25141226.

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2014 Name Roelof Ettema PhD defense March 13th, 2014 Schuurmans, Kalkman, Moons, Peelen PhD team Speciality Principal lecturer and Researcher Position Postdoctoral Researcher Department Knowledge Centre Innovation in Healthcare Location University of Applied Sciences Utrecht City Utrecht Country The Netherlands Quote “Development and implementation of integrated care pathways in care and welfare for the elderly will serve us all “ MAIN PAPER Ettema RG, Hoogendoorn ME, Kalkman CJ, Schuurmans MJ. Development of a nursing intervention to prepare frail older patients for cardiac surgery (the PREDOCS programme), following phase one of the guidelines of the Medical Research Council. Eur J Cardiovasc Nurs. 2014 Dec;13(6):494-505. PubMed PMID: 24186065.

2014 Name Merel Huisman PhD defense December 16th, 2014 PhD team van Vulpen, van den Bosch, Verkooijen Speciality Radiology Position Resident in Radiology Department Radiology Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “I feel privileged that I was able to spend four full years devoted to research in all its aspects in a great academic environment, and I hope younger generations can continue to do so, as research is the cornerstone of personal and societal academic development” MAIN PAPER Huisman M, Lam MK, Bartels LW, Nijenhuis RJ, Moonen CT, Knuttel FM, et al. Feasibility of volumetric MRI-guided high intensity focused ultrasound (MR-HIFU) for painful bone metastases. J Ther Ultrasound. 2014 Oct 10;2:16. PubMed PMID: 25309743.

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2014 Name Pushpa Jairam PhD defense April 10th, 2104 PhD team Van der Graaf, Mali, Verkooijen, de Jong Speciality Radiology Resident in Radiology Position Department Radiology Leiden University Medical Center Location City Leiden Country The Netherlands Quote “Whatever the mind of man can conceive and believe, it can achieve.” –Napoleon Hill MAIN PAPER Jairam PM, van der Graaf Y, Lammers JW, Mali WP, de Jong PA; PROVIDI Study group. Incidental findings on chest CT imaging are associated with increased COPD exacerbations and mortality.

Thorax. 2015 Aug;70(8):725-31. PubMed PMID: 26024687.

2014 Name Hennie Janssen PhD defense January 28th, 2014 PhD team Van der Schouw, Verhaar, Emmelot-Vonk Sleep medicine Speciality Position Pulmonologist/Somnologist Department Center for Sleep Medicine Kempenhaeghe Location Center for Sleep Medicine Kempenhaeghe City Heeze Country The Netherlands “Sleep is an important part of the day” Quote MAIN PAPER Janssen HC, Emmelot-Vonk MH, Verhaar HJ, van der Schouw YT. Vitamin D and muscle function: is there a threshold in the relation?

J Am Med Dir Assoc. 2013 Aug;14(8):627.e13-8. PMID: 23810236.

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2014 Raoul Kloppenburg Name PhD defense January 1st, 2014 PhD team Vermeulen, van der Graaf, Nederkoorn, Geerlings Speciality Neurology Position Neurologist in Neurovascular disease and Multiple Sclerosis Department Neurology Location Franciscus Hospital City Rotterdam Country The Netherlands Quote “Clinical neurology is to neuroscience what sex is to masturbation “- inspired by Richard Feynman MAIN PAPER Kloppenborg RP, Nederkoorn PJ, Grool AM, Vincken KL, Mali WP, Vermeulen M, et al. Cerebral small-vessel disease and progression of brain atrophy: the SMART-MR study. Neurology. 2012 Nov 13;79(20):2029-36. PubMed PMID: 23115210.

2014 Name Liselotte Kok PhD defense July 1st, 2014 PhD team de Wit, Moons, Muris, Elias Speciality Psychiatrie Position AIOS Psychiatrie Department Polikliniek Psychiatrie Location Tergooi ziekenhuis City Blaricum Country The Netherlands Quote “The intuitive mind is where our genius resides”.

MAIN PAPER Kok L, Elias SG, Witteman BJ, Goedhard JG, Romberg-Camps MJ, Muris JW, et al. Application of the Rome III criteria is not likely to reduce the number of unnecessary referrals for colonoscopy in primary care. Eur J Gastroenterol Hepatol. 2013 May;25(5):568-74.

PubMed PMID: 23325277.

256 20 years Julius Center; 1996-2017

2014 Name Minke Kooistra PhD defense October 16th, 2014 PhD team Van der Graaf, Biessels, Geerlings Speciality Staff member Position Staff member scientific affairs Alzheimer Nederland Department Location Alzheimer Nederland City Amersfoort The Netherlands Country Quote “A pessimist sees the difficulty in every opportunity; an optimist sees the opportunity in every difficulty” MAIN PAPER Kooistra M, Geerlings MI, van der Graaf Y, Mali WP, Vincken KL, Kappelle LJ, et al. SMART-MR Study Group.. Vascular brain lesions, brain atrophy, and cognitive decline. The Second Manifestations of ARTerial disease--Magnetic Resonance (SMART-MR) study. Neurobiol Aging. 2014 Jan;35(1):35-41. PubMed PMID: 23932882.

2014 Rob van Kruijsdijk Name PhD defense December 16th, 2014 Van der Graaf, PhD team Internal Medicine, nephrology Speciality Resident in Internal Medicine Position Department Hypertension and Nephrology University Medical Center Utrecht Location City Utrecht Country The Netherlands Quote “...”

MAIN PAPER van Kruijsdijk RC, Visseren FL, Ridker PM, Dorresteijn JA, Buring JE, van der Graaf Y, Cook NR. Individualised prediction of alternate-day aspirin treatment effects on the combined risk of cancer, cardiovascular disease and gastrointestinal bleeding in healthy women.

Heart. 2015 Mar;101(5):369-76. PubMed PMID: 25475110

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2014 Name Joep van der Leeuw PhD defense December 9th, 2014 PhD team Visseren, Van der Graaf Speciality Internal Medicine Position Resident in Internal Medicine Department Location Gelderse Vallei Hospital City Ede Country The Netherlands Quote “Geloof jij dit? “ MAIN PAPER van der Leeuw J, Visseren FL, Woodward M, van der Graaf Y, Grobbee DE, Harrap S, Heller S, et al. Estimation of individual beneficial and adverse effects of intensive glucose control for patients with type 2 diabetes. Diabetologia. 2016 Dec;59(12):26032612. PubMed PMID: 27586250.

2014 Name Rosa van Mansfeld PhD defense November 27th, 2014 PhD team Bonten, van der Ent, Willems Speciality Medical Microbiology Position Clinical Microbiologist Department Microbiology Location VU University Medical Center Amsterdam City Amsterdam Country The Netherlands Quote “…”

MAIN PAPER van Mansfeld R, de Vrankrijker A, Brimicombe R, Heijerman H, Teding van Berkhout F, Spitoni C, et al. The Effect of Strict Segregation on Pseudomonas aeruginosa in Cystic Fibrosis Patients. PLoS One. 2016 Jun 9;11(6):e0157189. PubMed PMID: 27280467.

258 20 years Julius Center; 1996-2017

2014 Name Ira Mostovaya PhD defense May 22nd, 2014 PhD team Bots, Verhaar, Blankestijn, Grooteman Speciality Epidemiology Position Advisor Department Knowledge Institute of Medical Specialists (Kennisinstituut van Medisch Specialisten) Domus Medica Location City Utrecht The Netherlands Country Quote “Preventing disease is always better than trying to manage the disease. Especially when it comes to renal replacement therapy.”

MAIN PAPER Mostovaya IM, Bots ML, van den Dorpel MA, Grooteman MP, Kamp O, Levesque R, et al. A randomized rial of hemodiafiltration and change in cardiovascular parameters. Clin J Am Soc Nephrol. 2014 Mar;9(3):520-6. PubMed PMID: 24408114.

2014 Maaike van Mourik Name PhD defense September 30th, 2014 Bonten, Moons, Troelstra PhD team Medical Microbiology Speciality Resident in Medical Microbiology Position Department Medical Microbiology University Medical Center Utrecht Location City Utrecht Country The Netherlands Quote “Don’t let perfect be the enemy of good” – paraphrased from Voltaire MAIN PAPER van Mourik MS, Troelstra A, van Solinge WW, Moons KG, Bonten MJ. Automated surveillance for healthcare-associated infections: opportunities for improvement. Clin Infect Dis. 2013 Jul;57(1):85-93.

PubMed PMID: 23532476.

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2014 Name PhD defense PhD team Speciality Position Department Location City Country Quote

Yvonne van Mourik November 25th, 2014 Hoes, Moons, Rutten, Reitsma General Practice General Practitioner Varying practices and health care centers Vicinity of utrecht The Netherlands “Love what you do and do it well”

MAIN PAPER van Mourik Y, Bertens LC, Cramer MJ, Lammers JW, Reitsma JB, Moons KG, et al. Unrecognized heart failure and chronic obstructive pulmonary disease (COPD) in frail elderly detected through a near-home targeted screening strategy. J Am Board Fam Med. 2014 Nov-Dec;27(6):811-21. PubMed PMID: 25381079.

2014 Name Louise van Oeffelen PhD defense June 3rd, 2014 PhD team Bots, Stronks, Vaartjes, Agyemang Speciality Epidemiology Position Postdoctoral Researcher Department Sexually Transmitted Diseases Location National Institute for public health and the environment (RIVM) & Public Health Service Rotterdam City Bilthoven & Rotterdam Country The Netherlands Quote “...”

MAIN PAPER van Oeffelen AA, Vaartjes I, Stronks K, Bots ML, Agyemang C. Incidence of acute myocardial infarction in first and second generation minority groups: does the second generation converge towards the majority population? Int J Cardiol. 2013 Oct 15;168(6):5422-9.PubMed PMID: 24035066.

260 20 years Julius Center; 1996-2017

2014 Name PhD defense PhD team Speciality Position Department Location City Country Quote

Tamara Platteel December 11th, 2016 Bonten, Cohen-Stuart, Leverstein-van Hall General Practice General Practitioner Varying practices and health care centers Vicinity of Utrecht The Netherlands “παντα ρει και ουδεν μενει”

MAIN PAPER Platteel TN, Cohen Stuart JW, de Neeling AJ, Voets GM, Scharringa J, van de Sande N, et al. ESBL national surveillance working group.

Multi-centre evaluation of a phenotypic extended spectrum β-lactamase detection guideline in the routine setting. Clin Microbiol Infect. 2013 Jan;19(1):70-6. PubMed PMID: 22268620.

2014 Name Stephan Ripke PhD defense March 23rd, 2014 PhD team Bakker, Kahn Speciality Psychiatry Group leader, Prinicipal Investigator Position Department Klinik für Psychiatrie und Psychotherapie Location Charite City Berlin Country Germany Quote “...”

MAIN PAPER Schizophrenia Working Group of the Psychiatric Genomics Consortium. Biological insights from 108 schizophrenia-associated genetic loci. Nature. 2014 Jul 24;511(7510):421-7. PubMed PMID: 25056061;

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2014 Arnoud Floriaan Schmidt Name PhD defense June 23rd, 2014 PhD team Hoes, Nielen, Klungel, Groenwold Speciality Epidemiology Position Postdoctoral Researcher Department Institute of Cardiovascular Science, Faculty of Population Health Location University College London City London Country United Kingdom Quote “…”

MAIN PAPER Schmidt AF, Klugkist I, Klungel OH, Nielen M, de Boer A, Hoes AW, Groenwold RH. Bayesian methods including nonrandomized study data increased the efficiency of postlaunch RCTs. J Clin Epidemiol.

2015 Apr;68(4):387-96. PubMed PMID: 25554520.

2014 Name Wouter Schonewille PhD defense December 4th, 2014 PhD team Kappelle, Algra Speciality Neurology Position Neurologist Department Neurology Location St. Antonius Hospital City Nieuwegein Country The Netherlands Quote “…”

MAIN PAPER Schonewille WJ, Wijman CA, Michel P, Rueckert CM, Weimar C, Mattle HP, et al. BASICS study group. Treatment and outcomes of acute basilar artery occlusion in the Basilar Artery International Cooperation Study (BASICS): a prospective registry study. Lancet Neurol. 2009 Aug;8(8):724-30. PubMed PMID: 19577962.

262 20 years Julius Center; 1996-2017

2014 Name Henrike Schouten PhD defense April 22nd, 2014 PhD team Moons, van Delden, Koek, Geersing Speciality Geatric Medicin Resident in Geriatric Medicine Position Department Geriatric Medicine Tergooi Hospital Location City Blaricum Country The Netherlands Quote “Overdiagnostiek bij ouderen, baat het niet, dan schaadt het wel” MAIN PAPER Schouten HJ, Geersing GJ, Koek HL, Zuithoff NP, Janssen KJ, Douma RA, et al. Diagnostic accuracy of conventional or age adjusted D-dimer cut-off values in older patients with suspected venous thromboembolism: systematic review and meta-analysis. BMJ. 2013 May 3;346:f2492. PubMed PMID: 23645857.

2014 Name Jessica van Setten PhD defense June 26th, 2014 PhD team Bakker, Cuppen Cardiovascular genetics Speciality Postdoctoral Researcher Position Department Cardiology, Divison Heart & Lungs University Medical Center Utrecht Location City Utrecht Country The Netherlands Quote “If at first you don’t succeed, try two more times so that your failure is statistically significant“ MAIN PAPER van der Harst P, van Setten J, Verweij N, et al. 52 Genetic Loci Influencing Myocardial Mass. J Am Coll Cardiol. 2016 Sep 27;68(13):1435-48. PubMed PMID: 27659466.

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2014 Name Lotje Steins Bisschop PhD defense March 24th, 2014 Peeters, van der Wall, May, Velthuis PhD team Speciality Psychiatry Position Psychiatrist Department Psychiatry Location Academic Medical Center - University of Amsterdam City Amsterdam Country The Netherlands Quote “The first symptom of the process of killing our dreams is the lack of time’ - Paulo Coelho MAIN PAPER Steins Bisschop CN, van Gils CH, Emaus MJ,et al. Weight change later in life and colon and rectal cancer risk in participants in the EPIC-PANACEA study. Am J Clin Nutr. 2014 Jan;99(1):139-47.

PubMed PMID: 24225355.

2014 Name Ellen Struijk PhD defense October 16th, 2014 PhD team Peeters, May, Beulens Speciality Epidemiology of Nutrition and Lifestyle Position Postdoctoral Researcher Department Faculty of Preventive Medicine and Public Health - Cardiovascular and Nutritional Epidemiology group Location Universidad Autónoma de Madrid City Madrid Country Spain Quote “No single food will make or break good health.

But the kinds of food you choose day in and day out have a major impact“ -Walter Willett MAIN PAPER May AM, Struijk EA, Fransen HP, Onland-Moret NC, de Wit GA, Boer JM, et al. The impact of a healthy lifestyle on Disability-Adjusted Life Years: a prospective cohort study. BMC Med. 2015 Feb 27;13:39.

PubMed PMID: 25858161; 264 20 years Julius Center; 1996-2017

2014 Name Vesna Svircevic PhD defense July 3rd, 2014 PhD team Kalkman, Moons, van Dijk, Nierich Speciality Anaesthesiology Position Anaesthesiologist Department Anaethesiology Catharina Hospital Eindhoven Location City Eindhoven Country The Netherlands Quote “…”

MAIN PAPER Svircevic V, Nierich AP, Moons KG, Diephuis JC, Ennema JJ, Brandon Bravo Bruinsma GJ, et al. Thoracic epidural anesthesia for cardiac surgery: a randomized trial. Anesthesiology. 2011 Feb;114(2):262-70. PubMed PMID: 21239976.

2014 Name Vinicius Tragante PhD defense June 24th, 2014 PhD team Doevendans, de Bakker, Asselbergs Speciality Bioinformatics Postdoctoral Researcher Position Department Heart & Lungs Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “They did not know it was impossible, so they did it!“ – Mark twain MAIN PAPER Tragante V, Barnes MR, Ganesh SK, Lanktree MB, Guo W, Franceschini N,et al. Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple bloodpressure-related loci. Am J Hum Genet. 2014 Mar 6;94(3):349-60.

PubMed PMID: 24560520;

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2014 Erika van der Veen Name PhD defense December 16th, 2014 PhD team Van der Graaf, Mali, Geerlings Speciality Radiology Position Resident in Radiology Department Radiology Location Gelre Hospital City Apeldoorn Country The Netherlands Quote “de aanhouder wint” MAIN PAPER van der Veen PH, Muller M, Vincken KL, Witkamp TD, Mali WP, van der Graaf Y, et al. SMART-MR Study Group. Longitudinal changes in brain volumes and cerebrovascular lesions on MRI in patients with manifest arterial disease: the SMART-MR study. J Neurol Sci. 2014 Feb 15;337(1-2):112-8. PubMed PMID: 24314719.

2014 Name Magrit Vermeulen PhD defense July 3rd, 2014 PhD team Damoiseaux, van der Graaf, Pieters, Kuyvenhoven Speciality General Practice Position Manager Development Department General Practice, Julius Center for Health Sciences and Primary care Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “…”

MAIN PAPER Vermeulen MI, Kuyvenhoven MM, de Groot E, Zuithoff NP, Pieters HM, van der Graaf Y, Damoiseaux RA. Poor Performance Among Trainees in a Dutch Postgraduate GP Training Program. Fam Med. 2016 Jun;48(6):430-8. PubMed PMID: 27272419.

266 20 years Julius Center; 1996-2017

2014 Eva Vink Name PhD defense June 10th, 2014 Verhaar, Bots, Blankestijn PhD team Speciality Internal Medicine Position Resident in Internal Medicine Department Internal Medicine and Department of ICU Location University Medical Center Utrecht and New Yorik University City Utrecht & New York Country The Netherlands & United States of America Quote “To successfully complete your PhD thesis/project, you need excellent secretary skills” MAIN PAPER Vink EE, de Boer A, Hoogduin HJ, Voskuil M, Leiner T, Bots ML, et al.

Renal BOLD-MRI relates to kidney function and activity of the renin-angiotensin-aldosterone system in hypertensive patients. J Hypertens. 2015 Mar;33(3):597-603; discussion 603-4.PubMed PMID: 25479032.

2014 Name Anneke de Vos PhD defense Okotober 28th, 2014 PhD team Kretzschmar, Prins Speciality Epidemiology of Infectious Diseases Position Currently unemployed Department Location City Diemen Country The Netherlands Quote “Nothing is permanent. Everything is subject to change. Being is always becoming.“ - Buddha MAIN PAPER de Vos AS, Janssen MP, Zaaijer HL, Hogema BM. Cost-effectiveness of the screening of blood donations for hepatitis E virus in the Netherlands. Transfusion. 2017 Feb;57(2):258-266.PubMed PMID: 28144956.

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2014 Miriam Warnier Name PhD defense February 19th, 2014 PhD team De Boer, Hoes, de Bruin, Rutten Speciality General Practice Position General Practitioner Department Location Huisartsenpraktijk Moen & Warnier City Doorwerth Country The Netherlands Quote “...”

MAIN PAPER Warnier MJ, Blom MT, Bardai A, Berdowksi J, Souverein PC, Hoes AW, et al. Increased risk of sudden cardiac arrest in obstructive pulmonary disease: a case-control study. PLoS One. 2013 Jun 6;8(6):e65638. PubMed PMID: 23755262.

2014 Name Merel Wassenaar PhD defense December 11th, 2014 PhD team Egberts, Sander, Leijten, Uijl Speciality Clinical Epidemiology Position Postdoctoral Researcher Department Epilepsy Research Location Stichting Epilepsie Instellingen Nederland (SEIN) City Heemstede Country The Netherlands Quote “No medicine cures what happiness cannot”Gabriel Garcia MárqueD MAIN PAPER Wassenaar M, van Heijl I, Leijten FS, van der Linden P, Uijl SG, Egberts AC, et al.Treatment of epilepsy in daily clinical practice: have outcomes improved over the past 10 years? J Neurol. 2013 nov;260(11):2736-43. PubMed PMID: 23893002.

268 20 years Julius Center; 1996-2017

2014 Name Lieke Wielders PhD defense July 1st, 2014 PhD team Couthinho, Schneeberger, van der Hoek Speciality Epidemiology Position Senior Epidemiologist Department Centre for Infectious Diseases, Epidemiology and Surveillance (EPI), Centre for Infectious Disease Control (CIb) Location National Institute for Public Health and the Environment (RIVM) City Bilthoven Country The Netherlands Quote “Remember to explore“ MAIN PAPER Wielders CC, van Loenhout JA, Morroy G, Rietveld A, Notermans DW, Wever PC,et al. Long-Term Serological Follow-Up of Acute Q-Fever Patients after a Large Epidemic. PLoS One. 2015 Jul 10;10(7):e0131848. PubMed PMID: 26161658.

2014 Name Laura Wisse PhD defense June 23rd, 2014 PhD team Biessels, van der Graaf, Geerlings Speciality Neuroscience Position Postdoctoral Researcher Department Radiology Location University of Pennsylvania City Philadelphia Country United States of America Quote “...”

MAIN PAPER Wisse LE, Adler DH, Ittyerah R, Pluta JB, Robinson JL, Schuck T, et al.

Comparison of In Vivo and Ex Vivo MRI of the Human Hippocampal Formation in the Same Subjects. Cereb Cortex. 2016 Sep 24.

PubMed PMID: 27664967.

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2014 Name Anton van de Woestijne PhD defense January 30th, 2014 PhD team Visseren, van der Graaf Speciality General Practice General Practitioner Position Department Various centers for primary care Various General Practices Location City Country The Netherlands Quote “...�

MAIN PAPER van de Woestijne AP, van der Graaf Y, Liem AH, Cramer MJ, Westerink J, Visseren FL; SMART Study Group. Low high-density lipoprotein cholesterol is not a risk factor for recurrent vascular events in patients with vascular disease on intensive lipid-lowering medication. J Am Coll Cardiol. 2013 Nov 12;62(20):1834-41. PubMed PMID: 23948286.

Class of

2015

2015 Paul Berger Name PhD defense March 10th, 2015 PhD team Bots, Blankensteijn, Vaartjes Speciality Vascular Surgery Position Vascular Surgeon Department Surgery Location Admiraal de Ruyter Hospital City Goes Country The Netherlands Quote “Vincent are we happy?”

MAIN PAPER Berger P, Vaartjes I, Scholtens A, Moll FL, De Borst GJ, De Keizer B, Bots ML, Blankensteijn JD. Differential FDG-PET Uptake Patterns in Uninfected and Infected Central Prosthetic Vascular Grafts. Eur J Vasc Endovasc Surg. 2015 Sep;50(3):376-83. PubMed PMID: 26164091.

2015 Name Timo Bolt PhD defense September 22nd, 2015 PhD team Huisman, Vandenbroucke Speciality Medial History Position Assistant Professor Department Public Health Location Erasmus Medical Center City Rotterdam Country The Netherlands Quote “Where is the wisdom we have lost in knowledge?

Where is the knowledge we have lost in information?“ MAIN PAPER Bolt TC, Huisman FG. [David Sackett and 25 years of evidence-based medicine: person and the context]. Ned Tijdschr Geneeskd.

2015;159:A9297. Dutch. PubMed PMID: 26306487.

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2015 Name Leandra Boonman-de Winter PhD defense April 28th, 2015 PhD team Hoes, Rutten, Cramer Speciality Epidemiology Position Manager Team Science Department Amphia Academy Location Amphia Hospital City Breda Country The Netherlands Quote “Appraisal and implementing results of research is important to establish a better and efficient health care, and improving quality of life of patients” MAIN PAPER Boonman-de Winter LJ, Rutten FH, Cramer MJ, Landman MJ, Liem AH, Rutten GE, Hoes AW. High prevalence of previously unknown heart failure and left ventricular dysfunction in patients with type 2 diabetes. Diabetologia. 2012 Aug;55(8):2154-62. PubMed PMID: 22618812;

2015 Name Kim Boshuisen PhD defense September 1st, 2015 PhD team Braun, Uiterwaal Speciality Neurology Position Resident in Paediatric Neurology Department Neurology Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “…”

MAIN PAPER Boshuisen K, Arzimanoglou A, Cross JH, Uiterwaal CS, Polster T, van Nieuwenhuizen O, Braun KP; TimeToStop study group. Timing of antiepileptic drug withdrawal and long-term seizure outcome after paediatric epilepsy surgery (TimeToStop): a retrospective observational study. Lancet Neurol. 2012 Sep;11(9):784-91. PubMed PMID: 22841352.

276 20 years Julius Center; 1996-2017

2015 Name Stan Buckens PhD defense April 24th, 2015 PhD team Van der Graaf, Mali, de Jong, Verkooijen Speciality Radiology Position Resident in Radiology Department Diagnostic Radiology Location Gelre Hospital City Apeldoorn Country The Netherlands Quote “Age quod agis” MAIN PAPER Buckens CF, de Jong PA, Mali WP, Verhaar HJ, van der Graaf Y, Verkooijen HM. Prevalent vertebral fractures on chest CT: higher risk for future hip fracture. J Bone Miner Res. 2014 Feb;29(2):392-8.

PubMed PMID: 23821454.

2015 Name Marjo Campmans-Kuijpers PhD defense June 16th, 2015 PhD team Rutten, Speciality Nutritional Epidemiology Position Postdoctoral Researcher Department Gastroenterology and Hepatology Location University Medical Center Groningen City Groningen Country The Netherlands Quote “Je bent nooit te oud om te leren” MAIN PAPER Campmans-Kuijpers MJ, Baan CA, Lemmens LC, Rutten GE. Change in quality management in diabetes care groups and outpatient clinics after feedback and tailored support. Diabetes Care. 2015 Feb;38(2):285-92. PubMed PMID: 25488914.

20 years Julius Center; 1996-2017 277

2015 Laurens de Cocker Name PhD defense December 10th, 2015 PhD team Hendrikse, Luijten, Geerlings Speciality Radiology Position (Neuro) Radiologist Department Radiology Location AZ Maria Middelares City Ghent Country Belgium Quote “A moment enjoyed, is never wasted” MAIN PAPER De Cocker LJ, Kloppenborg RP, van der Graaf Y, Luijten PR, Hendrikse J, Geerlings MI; SMART Study Group.. Cerebellar Cortical Infarct Cavities: Correlation With Risk Factors and MRI Markers of Cerebrovascular Disease. Stroke. 2015 Nov;46(11):3154-60. PubMed PMID: 26382175.

2015 Name Annette Compter PhD defense September 11th, 2015 PhD team Kappelle, Algra, van der Worp Speciality Neurology Position Neurologist Department Neurology Location Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital & Medical Center Slotervaart City Amsterdam Country The Netherlands Quote “Let the dots come together” - Steve Jobs MAIN PAPER Compter A, van der Worp HB, Schonewille WJ, Vos JA, Boiten J, Nederkoorn PJ, et al. VAST investigators. Stenting versus medical treatment in patients with symptomatic vertebral artery stenosis: a randomised open-label phase 2 trial. Lancet Neurol. 2015 Jun;14(6):606-14. PubMed PMID: 25908089.

278 20 years Julius Center; 1996-2017

2015 Mirjam Dautzenberg Name PhD defense December 10th, 2015 PhD team Bonten Speciality Medical Microbiology Position Resident in Clinical Microbiology Department Clinical Microbiology Location Canisius-Wilhelmina Hospital, Radboud University Medical Center City Nijmegen Country The Netherlands Quote “…”

MAIN PAPER Dautzenberg MJ, Haverkate MR, Bonten MJ, Bootsma MC. Epidemic potential of Escherichia coli ST131 and Klebsiella pneumoniae ST258: a systematic review and meta-analysis. BMJ Open. 2016 Mar 17;6(3):e009971. PubMed PMID: 26988349.

2015 Name Jan Dieleman PhD defense September 29th, 2015 PhD team Van Dijk, Kalkman, Moons Speciality Anaesthesiology Position Cardiac Anesthesiologist Department Anesthesiology Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “...”

MAIN PAPER Dieleman JM, Nierich AP, Rosseel PM, van der Maaten JM, Hofland J, Diephuis JC, et al. Dexamethasone for Cardiac Surgery (DECS) Study Group. Intraoperative high-dose dexamethasone for cardiac surgery: a randomized controlled trial. JAMA. 2012 Nov 7;308(17):1761-7. PubMed PMID: 23117776.

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2015 Jacqueline van Dijk Name PhD defense January 9th, 2015 PhD team Kalkman, Schuurmans, van Wijck Speciality Nursing Sciences Position Nurse specialist with emphasis on pre- and postoperative pain Department Department of Anesthesiology Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “…”

MAIN PAPER van Dijk JF, Schuurmans MJ, Alblas EE, Kalkman CJ, van Wijck AJ. Postoperative pain: knowledge and beliefs of patients and nurses.

J Clin Nurs. 2017 Jan 2. PubMed PMID: 28042880.

2015 Name George Downward PhD defense May 2nd, 2015 PhD team Brunekreef, Vermeulen Speciality Environmental Health Epidemiology Position Environmental Epidemiologist Department Environmental Epidemiology, Institute for Risk Assessment Sciences Location Utrecht University City Utrecht Country The Netherlands Quote “…”.

MAIN PAPER Downward GS, Hu W, Rothman N, Reiss B, Wu G, Wei F, et al.

Outdoor, indoor, and personal black carbon exposure from cookstoves burning solid fuels. Indoor Air. 2016 Oct;26(5):784-95.

PubMed PMID: 26452237.

280 20 years Julius Center; 1996-2017

2015 Marloes Eeftens Name PhD defense June 22nd, 2015 PhD team Brunekreef, Hoek, Beelen Speciality Public Health Position Postdoctoral Researcher Department Physical Hazards and Health Location Swiss Tropical and Public Health Institute City Basel Country Switzerland Quote “…”

MAIN PAPER Eeftens M, Beelen R, de Hoogh K, Bellander T, Cesaroni G, Cirach M, et al. Development of Land Use Regression models for PM(2.5), PM(2.5) absorbance, PM(10) and PM(coarse) in 20 European study areas; results of the ESCAPE project. Environ Sci Technol. 2012 Oct 16;46(20):11195-205. PubMed PMID: 22963366.

2015 Name Marleen Emaus PhD defense March 31st, 2015 PhD team Peeters, van de Bosch, van Gils, Bakker Speciality Epidemiology of Cardiovascular Disease in Cancer Patients Position Postdoctoral Researcher Department Imaging Division Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “Het komt goed“ - Johan Emaus MAIN PAPER Emaus MJ, Bakker MF, Peeters PH, Loo CE, Mann RM, de Jong MD, et al. MR Imaging as an Additional Screening Modality for the Detection of Breast Cancer in Women Aged 50-75 Years with Extremely Dense Breasts: The DENSE Trial Study Design. Radiology.

2015 Nov;277(2):527-37. PubMed PMID: 26110667.

20 years Julius Center; 1996-2017 281

2015 Jacques Fellay Name PhD defense January 19th, 2015 PhD team de Bakker, Miedema Speciality Human Genomics of viral disease Position Professor Department School of Life Sciences, Global Health Institute, Fellay lab Location Ecole Polytechnique Federale de Lausanne City Lausanne Country Switzerland Quote “…”

MAIN PAPER McLaren PJ, Coulonges C, Bartha I, Lenz TL, Deutsch AJ, Bashirova A, et al. Polymorphisms of large effect explain the majority of the host genetic contribution to variation of HIV-1 virus load. Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):14658-63. PubMed PMID: 26553974.

2015 Name Laurent Francioli PhD defense April 9th, 2015 PhD team de Bakker Speciality Genetic Epidemiology Position Postdoctoral Fellow Department Analytic and Translational Genetics Unit & .

Program in Medical and Population Genetics Location Massachusetts General Hospital & The Broad Institute of Harvard and MIT City Boston & Cambridge Country United States of America Quote “…”

MAIN PAPER Francioli LC, Polak PP, Koren A, Menelaou A, Chun S, Renkens I; et al.

Genome-wide patterns and properties of de novo mutations in humans. Nat Genet. 2015 Jul;47(7):822-6. PubMed PMID: 25985141.

282 20 years Julius Center; 1996-2017

2015 Willemijn van Gemert Name PhD defense January 22nd, 2015 PhD team Peeters, Schuit, Monninkhof Speciality Nuclear Medicine Position Resident in Nuclear Medicine Department Nuclear Medicine Location Radboud University Medical Center City Nijmegen Country The Netherlands Quote “Life is best when you’re in your twenties (and thirties).”

MAIN PAPER van Gemert WA, Schuit AJ, van der Palen J, May AM, Iestra JA, Wittink H, et al. Effect of weight loss, with or without exercise, on body composition and sex hormones in postmenopausal women: the SHAPE-2 trial. Breast Cancer Res. 2015 Sep 2;17:120. PubMed PMID: 26330303.

2015 Name Hans Jurgen Gerbershagen PhD defense February 20th, 2015 PhD team Kalkman, Peelen, van Wijck Speciality Anaesthesiology Position Anaesthesiologist with emphasis on pain treatment Department Anesthesiology and Intensive Care Medicine Location Marienhospital Gelsenkirchen City Gelsenkirchen Country Germany Quote “…”

MAIN PAPER Gerbershagen HJ, Aduckathil S, van Wijck AJ, Peelen LM, Kalkman CJ, Meissner W. Pain intensity on the first day after surgery: a prospective cohort study comparing 179 surgical procedures.

Anesthesiology. 2013 Apr;118(4):934-44. PubMed PMID: 23392233.

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2015 Noor Giesbertz Name PhD defense March 19th, 2015 PhD team Van Delden, Bredenoord Speciality Clinical genetics Resident in Clinical Genetics Position Department Medical Genetics Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “...”

MAIN PAPER Giesbertz NA, Bredenoord AL, van Delden JJ. When Children Become Adults: Should Biobanks Re-Contact? PLoS Med. 2016 Feb 16;13(2):e1001959. PubMed PMID: 26881426

2015 Name Wendela Greven PhD defense April 21st, 2015 PhD team Biesma, de Valk, Beulens Speciality Endocrinology Position Internist-Endocrinologist Department Internal Medicine Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “...”

MAIN PAPER Greven WL, Beulens JW, Biesma DH, Faiz S, de Valk HW. Glycemic variability in inadequately controlled type 1 diabetes and type 2 diabetes on intensive insulin therapy: a cross-sectional, observational study. Diabetes Technol Ther. 2010 Sep;12(9):695-9. PubMed PMID: 20687867.

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2015 Name Manon Haverkate PhD defense December 10th, 2015 PhD team Bonten, Bootsma Speciality Infectious disease epidemiology Position Policy Advisor infectious diseases/antibiotic resistance Department Centre for Infectious Disease Control Location National Institute for Public Health and the Environment (RIVM) City Bilthoven Country The Netherlands Quote “…”

MAIN PAPER Haverkate MR, Platteel TN, Fluit AC, Cohen Stuart JW, Leversteinvan Hall MA, Thijsen SF, et al. Quantifying within-household transmission of extended-spectrum β-lactamase-producing bacteria.

Clin Microbiol Infect. 2017 Jan;23(1):46.e1-46.e7. PubMed PMID: 27596534.

2015 Name Francisco Hernandez PhD defense June 3rd, 2015 PhD team Pieters, Raaijmakers, Mantel, van Thiel Speciality Epidemiology Position Market Access consultant and medical writer Department Location Pharmerit International City Rotterdam Country The Netherlands Quote “…”

MAIN PAPER Hernandez JF, van Thiel GJ, Mantel-Teeuwisse AK, Raaijmakers JA, Pieters T. Restoring trust in the pharmaceutical sector on the basis of the SSRI case. Drug Discov Today. 2014 May;19(5):523-7. PubMed PMID: 24295641.

20 years Julius Center; 1996-2017 285

2015 Name Susanne Huijts PhD defense June 3rd, 2015 PhD team Bonten Speciality Pulmonology Position Resident in Pulmonology Department Respiratory Medicine Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “…”

MAIN PAPER Bonten MJ, Huijts SM, Bolkenbaas M, Webber C, Patterson S, Gault S, et al. Polysaccharide conjugate vaccine against pneumococcal pneumonia in adults. N Engl J Med. 2015 Mar 19;372(12):1114-25.

PubMed PMID: 25785969.

2015 Name Nikmah Salamia Idris PhD defense May 26th, 2015 PhD team Grobbee, Uiterwaal Speciality Cardiology Position Medical Doctor Department Child Health Faculty of Medicine Location University of Indonesia & Cipto Mangunkusumo General Hospital and Budi Kemuliaan Health Institute City Jakarta Country Indonesia Quote “...”

MAIN PAPER Idris NS, Grobbee DE, Burgner D, Cheung MM, Kurniati N, Uiterwaal CS. Effects of Pediatric HIV infection on childhood vasculature.

Eur Heart J. 2016 Dec 21;37(48):3610-3616. PubMed PMID: 26746627.

286 20 years Julius Center; 1996-2017

2015 Teus Kappen Name PhD defense May 12th, 2015 PhD team Kalkman, Moons, Vergouwe, van Klei Speciality Anaesthesiology Position Anaesthesiologist Department Anaesthesiology Location Unversity Medical Center Utrecht City Utrecht Country The Netherlands Quote “Een voorspelmodel is net als een model op de catwalk: overfit, trendafhankelijk en slechts een beperkte representatie van de werkelijkheid.”

MAIN PAPER Kappen TH, Moons KG, van Wolfswinkel L, Kalkman CJ, Vergouwe Y, van Klei WA. Impact of risk assessments on prophylactic antiemetic prescription and the incidence of postoperative nausea and vomiting: a cluster-randomized trial. Anesthesiology. 2014 Feb;120(2):343-54. PubMed PMID: 24105403.

2015 Name Marise Kasteleyn PhD defense March 3rd, 2015 PhD team Rutten, Schellevis, Vos, Rijken Speciality Epidemiology Position Postdoctoral Researcher Department Public Health and Primary Care and Department of Pulmonology Location Leiden University Medical Center City Leiden Country The Netherlands Quote “Without data you are just another person with an opinion.“ MAIN PAPER Kasteleyn MJ, Vos RC, Rijken M, Schellevis FG, Rutten GE. Effectiveness of tailored support for people with Type 2 diabetes after a first acute coronary event: a multicentre randomized controlled trial (the Diacourse-ACE study). Diabet Med. 2016 Jan;33(1):125-33.

PubMed PMID: 26031804.

20 years Julius Center; 1996-2017 287

2015 Name Gbenga Kayode PhD defense October 29th, 2015 PhD team Grobbee, Klipstein-Grobusch, Ansah Speciality Epidemiology of Infectious Diseases Position Senior researcher Department International Research Centre of Excellence (IRCE) Location Institute of Human Virology, City Abuja Country Nigeria Quote “The Lord is my shepherd.“ - Psalms 23.1 MAIN PAPER Uthman OA, Kayode GA, Adekanmbi VT. Individual and contextual socioeconomic determinants of knowledge of the ABC approach of preventing the sexual transmission of HIV in Nigeria: a multilevel analysis. Sex Health. 2013 Dec;10(6):522-9. PubMed PMID: 24157246.

2015 Name Ellen Kemler PhD defense December 8th, 2015 PhD team Bakcx, Hoes, van de Port Speciality Epidemiology of Injury Prevention and Child safety Position Postdoctoral Researcher Department Location VeiligheidNL City Amsterdam Country The Netherlands Quote “...”

MAIN PAPER Kemler E, van de Port I, Backx F, van Dijk CN. A systematic review on the treatment of acute ankle sprain: brace versus other functional treatment types. Sports Med. 2011 Mar 1;41(3):185-97. PubMed PMID: 21395362.

288 20 years Julius Center; 1996-2017

2015 Name Peter Klein Klouwenberg PhD defense January 23rd, 2015 PhD team Bonten, Cremer Speciality Medical Microbiology Position Resident in Clinical Microbiology Department Clinical Microbiology Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “…”

MAIN PAPER Klein Klouwenberg PM, van Mourik MS, Ong DS, Horn J, Schultz MJ, Cremer OL, et al. MARS Consortium.. Electronic implementation of a novel surveillance paradigm for ventilator-associated events.

Feasibility and validation. Am J Respir Crit Care Med. 2014 Apr 15;189(8):947-55. PubMed PMID: 24498886.

2015 Name Paula Koekkoek PhD defense May 26th, 2015 PhD team Rutten, Kappelle, Biessels Speciality General Practice Position General Practitioner Department Location Acting General Practitioner at varying locations City Utrecht Country The Netherlands Quote “Measuring is knowing (- meten is weten)” MAIN PAPER Koekkoek PS, Kappelle LJ, van den Berg E, Rutten GE, Biessels GJ. Cognitive function in patients with diabetes mellitus: guidance for daily care. Lancet Neurol. 2015 Mar;14(3):329-40. PubMed PMID: 25728442.

20 years Julius Center; 1996-2017 289

2015 Carla Koopman Name PhD defense April 2nd, 2015 PhD team Bots, Capewell, Vaartjes, van Dis Speciality Clinical Epidemiology Position Current looking for new adventure Department Location City Veenendaal Country The Netherlands Quote “…”

MAIN PAPER Koopman C, Vaartjes I, van Dis I, Verschuren WM, Engelfriet P, Heintjes EM, et al. Explaining the Decline in Coronary Heart Disease Mortality in the Netherlands between 1997 and 2007. PLoS One. 2016 Dec 1;11(12):e0166139. PubMed PMID: 27906998.

2015 Name Henk Kraijo PhD defense March 13th, 2015 PhD team Schrijvers, Brouwer, de Leeuw, van Exel Speciality Mental Health Care Position Board of Directors & Policy advisor Department Location Adviesbureau voor Zorgorganisaties (ACZ) City Twello Country The Netherlands Quote “…”

MAIN PAPER Kraijo H, Brouwer W, de Leeuw R, Schrijvers G, van Exel J. The perseverance time of informal carers of dementia patients: validation of a new measure to initiate transition of care at home to nursing home care. J Alzheimers Dis. 2014;40(3):631-42. PubMed PMID: 24496076.

290 20 years Julius Center; 1996-2017

2015 Name Juliën Labrie PhD defense January 22nd, 2015 PhD team van der Vaart, Lagro-Janssen, Fischer, Berghans Speciality Gynaecology Position Gynaecologist Department Obstetrics and Gynaecology Location Elisabeth-TweeSteden Hospital City Tilburg Country The Netherlands Quote “…”

MAIN PAPER Labrie J, Berghmans BL, Fischer K, Milani AL, van der Wijk I, Smalbraak DJ, et al. Surgery versus physiotherapy for stress urinary incontinence. N Engl J Med. 2013 Sep 19;369(12):1124-33. PubMed PMID: 24047061.

2015 Name Maarten Leusink PhD defense January 7th, 2015 PhD team de Boer, Bakker, Maitland, Onland-Moret Speciality Epidemiology Position Data Scientist Department Location DSW Health Care Insurance City Schiedam Country The Netherlands Quote “…”

MAIN PAPER Leusink M, de Keyser CE, Onland-Moret NC, Hofman A, Visser LE, Stricker BH, et al. No association between CYP3A4*22 and statin effectiveness in reducing the risk for myocardial infarction. Pharmacogenomics. 2014 Aug;15(11):1471-7. PubMed PMID: 25303298.

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2015 Name Wies Maarse PhD defense August 27th, 2015 PhD team Kon, van Delden, van der Mink Speciality Plastic Surgery Plastic surgeon Position Department Plastic Surgery University Medical Center Utrecht Location City Utrecht Country The Netherlands Quote “…”

MAIN PAPER Maarse W, Boonacker CW, Lapid O, Swanenburg De Veye HF, Weiner Z, Kon M, van Delden JJ, Mink van der Molen AB. Professional opinion on oral cleft during pregnancy: a comparison between Israel and The Netherlands. Prenat Diagn. 2015 Jun;35(6):544-8..

PubMed PMID: 25641702.

2015 Name Manon van der Meer PhD defense June 17th, 2015 PhD team Doevendans, van der Graaf, Appelman, Nathoe Speciality Cardiology Resdent in Cardiology Position Department Jeroen Bosch Hospital Location City ‘s Hertogenbosch Country The Netherlands Quote “The gin and tonic has saved more Englishmen’s lives and minds than all the doctors in the Empire” MAIN PAPER van der Meer MG, van der Graaf Y, Schuit E, Peelen LM, Verschuren WM, Boer JM, et al. Added Value of Female-Specific Factors Beyond Traditional Predictors for Future Cardiovascular Disease. J Am Coll Cardiol. 2016 May 3;67(17):2084-6. PubMed PMID: 27126538.

292 20 years Julius Center; 1996-2017

2015 Name Denise Montagne PhD defense April 20th, 2015 PhD team Brunekreef, Hoek Speciality Biostatistics Position Biostatistician Department Location Quest Pharmaceutical Services Contact Research organisation Netherlands (QPS Netherlands) City Groningen The Netherlands Country Quote “…”

MAIN PAPER Montagne D, Hoek G, Nieuwenhuijsen M, Lanki T, Pennanen A, Portella M, et al. Agreement of land use regression models with personal exposure measurements of particulate matter and nitrogen oxides air pollution. Environ Sci Technol. 2013 Aug 6;47(15):8523-31. PubMed PMID: 23786264.

2015 Christiana Naaktgeboren Name PhD defense September 24th, 2015 Moons, de Groot, Reitsma PhD team Clinical Epidemiology Speciality Position Postdoctoral Researcher Department Clinical Epidemiology, Julius Center for Health Sciences and Primary Care University Medical Center Utrecht Location City Utrecht The Netherlands Country Quote “To be uncertain is to be uncomfortable, but to be certain is to be ridiculous.” - Chinese Proverb” MAIN PAPER Naaktgeboren CA, de Groot JA, Rutjes AW, Bossuyt PM, Reitsma JB, Moons KG. Anticipating missing reference standard data when planning diagnostic accuracy studies. BMJ. 2016 Feb 9;352:i402.

PubMed PMID: 26861453.

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2015 Sophie Niemansburg Name PhD defense May 12th 2015 PhD team Van Delden, Dhert, Bredenoord Speciality Doctor of Infectious Disease Control Position Physician Department Location Public Health Service Rotterdam-Rijnmond en Dienst Gezondheid & Jeugd (Zuid Holland Zuid) City Rotterdam Country The Netherlands Quote “Leef, alsof de morgen niet bestaat” MAIN PAPER Niemansburg SL, van Delden JJ, Dhert WJ, Bredenoord AL. Regenerative medicine interventions for orthopedic disorders: ethical issues in the translation into patients. Regen Med. 2013 Jan;8(1):65-73. PubMed PMID: 23259806.

2015 Name Putri Novianti PhD defense June 2nd, 2015 PhD team Roes, Eijkemans Speciality Biostatistics Position Postdoctoral Researcher Department Epidemiology and Biostatistics & Department of Pathology Location VU University Medical Center Amsterdam City Amsterdam Country The Netherlands Quote “…”

MAIN PAPER Novianti PW, Snoek BC, Wilting SM, van de Wiel MA. Better diagnostic signatures from RNAseq data through use of auxiliary co-data. Bioinformatics. 2017 Jan 10. pii: btw837. PubMed PMID: 28073760.

294 20 years Julius Center; 1996-2017

2015 Name David Ong PhD defense December 8th, 2015 PhD team Bonten, Cremer Speciality Clinical Microbiology Resident in Clinical Microbiology Position Department Medical Microbiology University Medical Center Utrecht Location City Utrecht Country The Netherlands Quote “To achieve accurate estimations in observational studies, it is important to consider all kinds of bias, including time-dependent bias, competing events, confounding at baseline, and confounding due to the evolution of disease severity prior to the onset of a time-varying variable of interest.”

MAIN PAPER Ong DS, Spitoni C, Klein Klouwenberg PM, et al. Cytomegalovirus reactivation and mortality in patients with acute respiratory distress syndrome. Intensive Care Med. 2016 Mar;42(3):333-41. PubMed PMID: 26415682.

2015 Name Marlies Schrijvers PhD defense September 30th, 2015 PhD team Schuurmans, Fischer Nursing Sciences and Clinical Health Sciences Speciality Position Nursing Scientist and Staff member Clinical Health Sciences Department Education Center, Faculty of Medicine University Medical Center Utrecht Location City Utrecht The Netherlands Country Quote “Let us never consider ourselves finished nurses… we must be learning all of our lives” - Florence nightingale MAIN PAPER Schrijvers LH, Beijlevelt-van der Zande M, Peters M, Lock J, Cnossen MH, Schuurmans MJ, et al. Adherence to prophylaxis and bleeding outcome in haemophilia: a multicentre study. Br J Haematol. 2016 Aug;174(3):454-60. PubMed PMID: 27098446.

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2015 Name Judith Sittig PhD defense April 23rd, 2015 PhD team Moons, Nieuwenhuis, van der Putte, Uiterwaal Speciality Pediatric Medicine & Mental Health Care Position Resident in Pediatric Medicine Department Paediatrics Location Wilhelmina Children’s Hospital, University Medical Center Utrecht & The Netherlands Mental Health Care ‘GGZ Centraal Rembrandthof City Utrecht & Hilversum Country The Netherlands Quote “…”

MAIN PAPER Sittig JS, Uiterwaal CS, Moons KG, Russel IM, Nievelstein RA, Nieuwenhuis EE, van de Putte EM. Value of systematic detection of physical child abuse at emergency rooms: a cross-sectional diagnostic accuracy study. BMJ Open. 2016 Mar 22;6(3):e010788.

PubMed PMID: 27006346.

2015 Name Mirthe van der Valk PhD defense October 15th, 2015 PhD team Siersema, Oldenburg, Mengen Speciality Gastroenterology Position Gastroenterologist Department Gastroenterology Location Groote Schuur Hospital City Kaapstad Country South Africa Quote “…”

MAIN PAPER van der Valk ME, Mangen MJ, Leenders M, Dijkstra G, van Bodegraven AA, Fidder HH, et al. COIN study group and the Dutch Initiative on Crohn and Colitis.. Healthcare costs of inflammatory bowel disease have shifted from hospitalisation and surgery towards anti-TNFα therapy: results from the COIN study. Gut. 2014 Jan;63(1):72-9. PubMed PMID: 23135759.

296 20 years Julius Center; 1996-2017

2015 Name Jorien Veldwijk PhD defense May 12th, 2016 PhD team Smit, de Wit, Lambooij Speciality Patient Preferences Reseach Senior research fellow Position Department Center for Research Ethics and Bioethics & Public Health Uppsala University & Erasmus Medical Center Location City Uppsala & Rotterdam Sweden & Netherlands Country “Making decisions is never free from risk“ Quote MAIN PAPER Veldwijk J, Essers BA, Lambooij MS, Dirksen CD, Smit HA, de Wit GA. Survival or Mortality: Does Risk Attribute Framing Influence Decision-Making Behavior in a Discrete Choice Experiment? Value Health.

2016 Mar-Apr;19(2):202-9. PubMed PMID: 27021754.

2015 Name Natasha Verbakel PhD defense March 19th, 2015 PhD team Verheij, Wagner, Zwart, Langelaan Pharmaceutical Sciences Speciality Staff member quality and projectmanager Position Department Location Zorggroep DOH (Collaborative General Practitioner Group) City Eindhoven The Netherlands Country Quote “…”

MAIN PAPER Verbakel NJ, Langelaan M, Verheij TJ, Wagner C, Zwart DL. Effects of patient safety culture interventions on incident reporting in general practice: a cluster randomised trial. Br J Gen Pract. 2015 May;65(634):e319-29. PubMed PMID: 25918337.

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2015 Name Ilona Verhagen PhD defense April 14th, 2015 PhD team de Wit, Ros, Steunenberg Speciality Cultural Anthropology Position Lecturer / Senior researcher Department Institute of Social Studies Location Rotterdam University of Applied Sciences City Rotterdam Country The Netherlands Quote “It always seems impossible until it’s done“ N. Mandela MAIN PAPER Verhagen I, Ros WJ, Steunenberg B, de Wit NJ. Ethnicity does not account for differences in the health-related quality of life of Turkish, Moroccan, and Moluccan elderly in the Netherlands. Health Qual Life Outcomes. 2014 Oct 1;12:138. PubMed PMID: 25269442.

2015 Name Maaike Weijmans PhD defense November 26th, 2015 PhD team Visseren, van der Graaf Speciality Internal Medicine Position Resident in Internal Medicine Department Internal Medicine Location Gelre Hospital City Apeldoorn Country The Netherlands Quote “...”

MAIN PAPER Weijmans M, van der Graaf Y, Reitsma JB, Visseren FL. Paternal or maternal history of cardiovascular disease and the risk of cardiovascular disease in offspring. A systematic review and meta-analysis.

Int J Cardiol. 2015 Jan 20;179:409-16. PubMed PMID: 25464496.

298 20 years Julius Center; 1996-2017

2015 Name Henri van Werkhoven PhD defense October 6th, 2015 PhD team Bonten, Oosterheert Speciality Epidemiology of Infectious Diseases Postdoctoral Researcher Position Department Clinical Epidemiology, Julius Center for Health Sciences and Primary Care University Medical Center Utrecht Location City Utrecht The Netherlands Country Quote “To find out what happens to a system when you interfere with it you have to interfere with it, not just passively observe it”- George E.P. Box, 1966 MAIN PAPER Postma DF, van Werkhoven CH, van Elden LJ, Thijsen SF, Hoepelman AI, Kluytmans JA, et al. CAP-START Study Group.. Antibiotic treatment strategies for community-acquired pneumonia in adults. N Engl J Med. 2015 Apr 2;372(14):1312-23. PubMed PMID: 25830421.

2015 Aileen Yang Name PhD defense December 9th, 2015 Brunekreef, Cassee, Hoek, Janssen PhD team Environmental Health Epidemiology Speciality Postdoctoral Researcher Position Department Civil Engineering and Energy Technology, Oslo and Akershus University College Location City Oslo Country Norway Quote “Flow with whatever may happen and let your mind be free. Stay centered by accepting whatever you are doing.”

MAIN PAPER Yang A, Janssen NA, Brunekreef B, Cassee FR, Hoek G, Gehring U. Children’s respiratory health and oxidative potential of PM2.5: the PIAMA birth cohort study. Occup Environ Med. 2016 Mar;73(3):154-60. PubMed PMID: 26755634.

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Class of

2016

2016 Name Mary Amoakoh-Coleman PhD defense January 14th, 2016 PhD team Grobbee, Agyepong, Ansah, Klipstein-Grobusch Speciality Clinical Epidemiology Postdoctoral Researcher Position Department Noguchi Memorial Institute for Medical Research University of Ghana Location Legon, Accra City Country Ghana Quote “…You only know it is easy or difficult when you try…“ MAIN PAPER Amoakoh-Coleman M, Klipstein-Grobusch K, Agyepong IA, Kayode GA, Grobbee DE, Ansah EK. Provider adherence to first antenatal care guidelines and risk of pregnancy complications in public sector facilities: a Ghanaian cohort study. BMC Pregnancy Childbirth. 2016 Nov 24;16(1):369. PubMed PMID: 27881104;

2016 Name Henok Ayele PhD defense March 30th, 2016 Bonten, van Mourik PhD team Epidemiology of Infectious Disease Speciality Postdoctoral fellow Position Department Clinical Epidemiology, Lady Davis Institute Jewish General Hospital, McGill University City Location Montreal Country City Country Canada “It always seems impossible until it is done” Quote MAIN PAPER Ayele HT, van Mourik MS, Bonten MJ. Effect of isoniazid preventive therapy on tuberculosis or death in persons with HIV: a retrospective cohort study. BMC Infect Dis. 2015 Aug 13;15:334. PubMed PMID: 26269094

20 years Julius Center; 1996-2017 303

2016 Cindy Bekker Name PhD defense October 25th, 2016 PhD team Heederick, Vermeulen, Fransman Speciality Environmental Health Epidemiology Position Research Scientist Risks of Nanomaterials Department Centre for Substances and Integrated Risk Assessment Location National Institute for Public Health and the Environment (RIVM) City Bilthoven Country The Netherlands Quote “…”

MAIN PAPER Bekker C, Voogd E, Fransman W, Vermeulen R. The Validity and Applicability of Using a Generic Exposure Assessment Model for Occupational Exposure to Nano-Objects and Their Aggregates and Agglomerates. Ann Occup Hyg. 2016 Nov;60(9):1039-1048. PubMed PMID: 27637557.

2016 Name Nina Berentzen PhD defense April 19th, 2016 PhD team Smit, Wijga Speciality Epidemiology Position Postdoctoral Researcher Department Epidemiology Location Netherlands Cancer Institute City Amsterdam Country The Netherlands Quote “Two quite opposite qualities equally bias our minds – habits and novelty.” – Jean de la Bruyere MAIN PAPER Berentzen NE, van Rossem L, Gehring U, Koppelman GH, Postma DS, de Jongste JC, et al. Overweight patterns throughout childhood and cardiometabolic markers in early adolescence. Int J Obes (Lond). 2016 Jan;40(1):58-64. PubMed PMID: 26395749.

304 20 years Julius Center; 1996-2017

2016 Name Saskia van den Berg PhD defense May 19th, 2016 PhD team Smit, Boer Speciality Nutrional Epidemiology Postdoctoral Researcher Position Department Centre for Nutrition, Prevention and health Services Location National Institute for Public Health and the Environment (RIVM) City Bilthoven The Netherlands Country Quote “...”

MAIN PAPER van den Berg SW, Dollé ME, Imholz S, van der A DL, van ‘t Slot R, Wijmenga C, et al. Genetic variations in regulatory pathways of fatty acid and glucose metabolism are associated with obesity phenotypes: a population-based cohort study. Int J Obes (Lond). 2009 Oct;33(10):1143-52. PubMed PMID: 19652658.

2016 Name Süleyman Bilecen PhD defense December 13th, 2016 Moons, Kalkman, de Groot, Nierich PhD team Speciality Anaesthesiology Position Anaesthesiologist Department Intensive Care and Emergency Medicine University Medical Center Utrecht Location City Utrecht Country The Netherlands “I have many and none” Quote MAIN PAPER Bilecen S, de Groot JA, Kalkman CJ, Spanjersberg AJ, Brandon Bravo Bruinsma GJ, Moons KG, Nierich AP. Effect of Fibrinogen Concentrate on Intraoperative Blood Loss Among Patients With Intraoperative Bleeding During High-Risk Cardiac Surgery: A Randomized Clinical Trial. JAMA. 2017 Feb 21;317(7):738747PubMed PMID: 28241354

20 years Julius Center; 1996-2017 305

2016 Name Russel Brooke PhD defense March 23rd, 2016 Kretzschmar, Teunis PhD team Speciality Epidemiology Position Postdoctoral Researcher Department Epidemiology and Cancer Control Location St Jude Children’s Hospital City Memphis Country United States of America Quote “Never memorize something you can look up – Albert Einstein” MAIN PAPER rooke RJ, Kretzschmar ME, Hackert V, Hoebe CJ, Teunis PF, Waller LA. Spatial Prediction of Coxiella burnetii Outbreak Exposure via Notified Case Counts in a Dose-Response Model. Epidemiology.

2017 Jan;28(1):127-135. PubMed PMID: 27768623.

2016 Name Joyce Browne PhD defense October 4th, 2016 PhD team Grobbee, Speciality Global Health Epidemiology Position Assistant Professor Department Global Health, Julius Center for Health Sciences and Primary Care Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “Women are not dying because of diseases we cannot treat. They are dying because societies have yet to make the decision that their lives are worth saving. “ - Mahmoud Fathalla MAIN PAPER Browne JL, Klipstein-Grobusch K, Franx A, Grobbee DE. Prevention of Hypertensive Disorders of Pregnancy: a Novel Application of the Polypill Concept. Curr Cardiol Rep. 2016 Jun;18(6):59. PubMed PMID: 27209297; 306 20 years Julius Center; 1996-2017

2016 Name Sara Dekking PhD defense May 26th, 2016 PhD team van Delden, van der Graaf Speciality Medical Ethics Policy Advisor Position Department Ethics department Ministry of Health, Welfare and Sports Location The Hague City Country The Netherlands Quote “Life is a great big canvas and you should throw all the paint on it you can.“ – Danny Kaye MAIN PAPER Dekking SA, van der Graaf R, de Vries MC, Bierings MB, van Delden JJ, Kodish E, Lantos JD. Is a New Protocol for Acute Lymphoblastic Leukemia Research or Standard Therapy? Pediatrics. 2015 Sep;136(3):566-70. PubMed PMID: 26283776;

2016 Name Ruben Duijnhoven PhD defense January 18th, 2016 PhD team de Boer, Hoes, de Bruin, Straus Clinical Epidemiology Speciality Position Clinical Epidemiologist Department Clinical trials Consortium of the Dutch Society of Obstetrics and Gynaecology (NVOG Consortium), Gynaecology and Obstetrics Location Academic Medical Center – University of Amsterdam City Amsterdam Country The Netherlands Quote “…”

MAIN PAPER Duijnhoven RG, Straus SM, Raine JM, de Boer A, Hoes AW, De Bruin ML. Number of patients studied prior to approval of new medicines: a database analysis. PLoS Med. 2013;10(3):e1001407. PubMed PMID: 23526887.

20 years Julius Center; 1996-2017 307

2016 Anouk Eikendal Name PhD defense June 22nd, 2016 PhD team Leiner, Bots, den Ruijter, Höfer Speciality Internal Medicine Position Resident in Internal Medicine Department Internal Medicine Location Red Cross Hospital City Beverwijk Country The Netherlands Quote “...”

MAIN PAPER Eikendal AL, Groenewegen KA, Anderson TJ,et al.USE-IMT Project Group.. Common carotid intima-media thickness relates to cardiovascular events in adults aged <45 years. Hypertension. 2015 Apr;65(4):707-13. PubMed PMID: 25624341.

2016 Name Wouter Foppen PhD defense April 14th, 2016 PhD team Mali, Fischer, van der Schaaf Speciality Radiology Position Resident in Radiology Department Radiology Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “…”

MAIN PAPER Foppen W, van der Schaaf IC, Fischer K. Value of routine ultrasound in detecting early joint changes in children with haemophilia using the ‘Haemophilia Early Arthropathy Detection with UltraSound’ protocol. Haemophilia. 2016 Jan;22(1):121-5. PubMed PMID: 26228742.

308 20 years Julius Center; 1996-2017

2016 Name Heidi Fransen PhD defense February 16th, 2016 PhD team Peeters, May, Beulens Speciality Palliative care Postdoctoral Researcher Position Department Location Netherlands Comprehensive Cancer Organisation (IKNL) City Utrecht The Netherlands Country Quote “Leven toevoegen aan de dagen, waar vaak geen dagen meer kunnen worden toegevoegd aan het leven “ - Motto Roparun MAIN PAPER Fransen HP, Beulens JW, May AM, Struijk EA, Boer JM, de Wit GA, et al. Dietary patterns in relation to quality-adjusted life years in the EPIC-NL cohort. Prev Med. 2015 Aug;77:119-24. PubMed PMID: 26007298.

2016 Bas Franssens Name PhD defense September 22th, 2016 Van der Graaf, Visseren PhD team Internal Medicine Speciality Resident in Internal Medicine Position Department Internal Medicine Gelre Hospital Location City Apeldoorn Country The Netherlands Quote “...”

MAIN PAPER Franssens BT, Hoogduin H, Leiner T, van der Graaf Y, Visseren FL. Relation between brown adipose tissue and measures of obesity and metabolic dysfunction in patients with cardiovascular disease.

J Magn Reson Imaging. 2017 Jan 27. PubMed PMID: 28130811.

20 years Julius Center; 1996-2017 309

2016 Anoukh van Giessen Name PhD defense June 21st, 2016 PhD team Moons, de Wit, Koffijberg Speciality Health Technology Assessment Position Assistant Professor Department HTA, Julius Center for Health Science and Primary Care Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “…”

MAIN PAPER A. van Giessen, J. Peters, B. Wilcher, et al. Systematic Review of Health Economic Impact Evaluations of Risk Prediction Models: Stop Developing, Start Evaluating. Value in Health, April 2017, In Press.

2016 Name Remco Grobben PhD defense October 11th, 2016 PhD team Doevendans, van Klei, Nathoe, Peelen Speciality Cardiology Position Resident in Cardiology Department Cardiology, Divison Heart & Lungs Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “...”

MAIN PAPER van Waes JA, Grobben RB, Nathoe HM, Kemperman H, de Borst GJ, Peelen LM, van Klei WA; Cardiac Health After Surgery (CHASE) Investigators.. One-Year Mortality, Causes of Death, and Cardiac Interventions in Patients with Postoperative Myocardial Injury.

Anesth Analg. 2016 Jul;123(1):29-37. PubMed PMID: 27111647.

310 20 years Julius Center; 1996-2017

2016 Name Karlijn Groenewegen PhD defense January 19th, 2016 PhD team Bots, Peters, den Ruijter Speciality Geriatric Medicine Resident in Geriatric Medicine Position Department Clinical Geriatric Medicine Slotervaart Medical Center Location City Amsterdam Country The Netherlands Quote “If you don’t take a temperature, you can’t find a fever” - Samuel Shem – the house of god MAIN PAPER Groenewegen KA, den Ruijter HM, Pasterkamp G, Polak JF, Bots ML, Peters SA. Vascular age to determine cardiovascular disease risk: A systematic review of its concepts, definitions, and clinical applications. Eur J Prev Cardiol. 2016 Feb;23(3):264-74. PubMed PMID: 25609227.

2016 Name Michelle Habets PhD defense December 29th, 2016 Van Delden, Bredenoord PhD team Medical Ethics Speciality Postdoctoral Researcher Position Department Criminal Law Erasmus University Rotterdam Location City Rotterdam Country The Netherlands Quote “…”

MAIN PAPER Habets MG, van Delden JJ, Niemansburg SL, Atkins HL, Bredenoord AL. One Size Fits All?: Ethical Considerations for Examining Efficacy in First-in-Human Pluripotent Stem Cell Studies. Mol Ther. 2016 Dec;24(12):2039-2042. PubMed PMID: 27966562.

20 years Julius Center; 1996-2017 311

2016 Name Rianne van den Ham PhD defense May 25th, 2016 PhD team Leufkens, Klungel, van Staa Speciality Pharmacoepidemiology and Pharmaceutical Policy Position Research Associate & University Lecturer Department WHO Collaborating Centre for Pharmaceutical Policy and Regulation, Pharmacoepidemiology and Clinical Pharmacology Location Utrecht University City Utrecht Country The Netherlands Quote “Every patient is unique and should be treated as such “ MAIN PAPER van den Ham HA, Klungel OH, Singer DE, Leufkens HG, van Staa TP. Comparative Performance of ATRIA, CHADS2, and CHA2DS2-VASc Risk Scores Predicting Stroke in Patients With Atrial Fibrillation: Results From a National Primary Care Database. J Am Coll Cardiol.

2015 Oct 27;66(17):1851-9. PubMed PMID: 26493655.

2016 Name Wietse Ham PhD defense July 5th, 2016 PhD team Leenen, Schuurmans, Schoonhoven Speciality Emergency Care Position Nurse acute care and assistant professor Department Emergency Department & School of Nursing Location University Medical Center Utrecht & University of Applied Sciences Utrecht City Utrecht Country The Netherlands Quote “Life isn’t about waiting for the storm to pass, it’s about learning to dance in the rain…”

MAIN PAPER Ham W, Schoonhoven L, Schuurmans MJ, Leenen LP. Pressure ulcers from spinal immobilization in trauma patients: a systematic review.

J Trauma Acute Care Surg. 2014 Apr;76(4):1131-41.PubMed PMID: 24662882.

312 20 years Julius Center; 1996-2017

2016 Name Mojtaba Hashemi PhD defense July 5th, 2016 PhD team Moons, van den Berg, Fischer Speciality General Practice General Practitioner, assistant professor Position Department General Practice, Julius Center for Health Sciences and Primary Care University Medical Center Utrecht Location City Utrecht The Netherlands Country Quote “…”

MAIN PAPER Hashemi SM, Fischer K, Moons KG, van den Berg HM; PedNet Study group. Validation of the prediction model for inhibitor development in PUPs with severe haemophilia A. Haemophilia. 2016 Feb 8.

PubMed PMID: 26856685.

2016 Name Marijn Hazelbag PhD defense June 23rd, 2016 PhD team Hoes, Groenwold Speciality Biostatistics Assistant Professor Position Department Biostatistics, Julius Center for Health Sciences and Primary Care University Medical Center Utrecht Location City Utrecht The Netherlands Country “In God we trust. All others must bring data” Quote MAIN PAPER Hazelbag CM, Peters SA, Blankestijn PJ, Bots ML, Canaud B, Davenport A, et al. The importance of considering competing treatment affecting prognosis in the evaluation of therapy in trials: the example of renal transplantation in hemodialysis trials. Nephrol Dial Transplant 2017 (in press)

20 years Julius Center; 1996-2017 313

2016 Name Karst Heida PhD defense December 23rd, 2016 PhD team Franx, Bots, Oudijk Speciality Obstetrics and Gynaecology Resident in Obstetrics and Gynaecology Position Department Obstetrics and Gynaecology University Medical Center Utrecht Location City Utrecht Country The Netherlands “Life is better in pyjamas” Quote MAIN PAPER Heida KY, Bots ML, de Groot CJ, van Dunné FM, Hammoud NM, Hoek A, et al. Cardiovascular risk management after reproductive and pregnancy-related disorders: A Dutch multidisciplinary evidence-based guideline. Eur J Prev Cardiol. 2016 Nov;23(17):1863-1879.

PubMed PMID: 27432836.

2016 Name Janneke Hendriksen PhD defense February 9th, 2016 PhD team Moons, Schutgens, Geersing General Practice Speciality General Practitioner, assistant professor Position Department General Practice, Julius Center for Health Sciences and Primary Care University Medical Center Utrecht Location City Utrecht The Netherlands Country Quote “…”

MAIN PAPER Hendriksen JM, Geersing GJ, Lucassen WA, Erkens PM, Stoffers HE, van Weert HC,Büller HR, Hoes AW, Moons KG. Diagnostic prediction models for suspected pulmonary embolism: systematic review and independent external validation in primary care. BMJ. 2015 Sep 8;351:h4438. PubMed PMID: 26349907.

314 20 years Julius Center; 1996-2017

2016 Pauline Hennus Name PhD defense January 14th, 2016 PhD team de Jong, Hoes, de Kort Speciality Urology Position Resident in Urology Department Urology Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “…”

MAIN PAPER Hennus PM, de Kort LM, Bosch JL, de Jong TP, van der Heijden GJ. A systematic review on the accuracy of diagnostic procedures for infravesical obstruction in boys. PLoS One. 2014 Feb 20;9(2):e85474.

PubMed PMID: 24586242.

2016 Name Alexander Horsch PhD defense October 25th, 2016 PhD team Mali, van der Graaf, Velthuis, Dankbaar Speciality Radiology Position Interventional and Diagnostic Radiologist Department Radiology Location North Bristol NHS Trust City Bristol Country United Kingdom Quote “...”

MAIN PAPER Horsch AD, Dankbaar JW, Niesten JM, van Seeters T, van der Schaaf IC, van der Graaf Y, et al. Dutch Acute Stroke Study Investigators.

Predictors of reperfusion in patients with acute ischemic stroke.

AJNR Am J Neuroradiol. 2015 Jun;36(6):1056-62. PubMed PMID: 25907522.

20 years Julius Center; 1996-2017 315

2016 Gerben Hulsegge Name PhD defense March 31th, 2016 PhD team Verschuren, Smit Speciality Public and occupational health Position Postdoctoral Researcher Department Public and Occupational Health Location VU University Medical Center Amsterdam City Amsterdam Country The Netherlands Quote “The best protection for public health is prevention, not cleanup“ MAIN PAPER Hulsegge G, Picavet HS, Blokstra A, Nooyens AC, Spijkerman AM, van der Schouw YT, et al. Today’s adult generations are less healthy than their predecessors: generation shifts in metabolic risk factors: the Doetinchem Cohort Study. Eur J Prev Cardiol. 2014 Sep;21(9):1134-44. PubMed PMID: 23575972.

2016 Name Aleksandra Jedynska PhD defense March 15th, 2016 PhD team Brunekreef, Hoek, Kooter Speciality Applied Environmental Chemistry Position Postdoctoral Researcher Department Location Netherlands Organization for Applied Scientific Research (TNO) City Rotterdam Country The Netherlands Quote “…”

MAIN PAPER Jedynska A, Hoek G, Wang M, Eeftens M, Cyrys J, Keuken M, Ampe C, Beelen R, et al. Development of land use regression models for elemental, organic carbon, PAH, and hopanes/steranes in 10 ESCAPE/TRANSPHORM European study areas. Environ Sci Technol.

2014 Dec 16;48(24):14435-44. PubMed PMID:25317817.

316 20 years Julius Center; 1996-2017

2016 Nini Jonkman Name PhD defense June 9th, 2016 Schuurmans, Hoes, Trappenburg, Groenwold PhD team Speciality Clinical Epidemiology into stratified medicine Position Postdoctoral Researcher Department Human Movement Sciences Location VU University Medical Center Amsterdam City Amsterdam Country The Netherlands Quote “‘If you want to go fast, go alone. If you want to go far, go together.”

MAIN PAPER Jonkman NH, Westland H, Groenwold RH, Ågren S, Atienza F, Blue L, et al. Do Self-Management Interventions Work in Patients With Heart Failure? An Individual Patient Data Meta-Analysis. Circulation.

2016 Mar 22;133(12):1189-98. PubMed PMID: 26873943;i

2016 Name Lotte Kaasenbrood PhD defense December 1st, 2016 PhD team Visseren, van der Graaf, Dorresteijn Speciality Vascular Medicine Position Resident in Internal Medicine Department Internal Medicine Location St. Antonius Hospital City Nieuwegein Country The Netherlands Quote “...”

MAIN PAPER Kaasenbrood L, Boekholdt SM, van der Graaf Y, Ray KK, Peters RJ, Kastelein JJ, et al. Distribution of Estimated 10-Year Risk of Recurrent Vascular Events and Residual Risk in a Secondary Prevention Population. Circulation. 2016 Nov 8;134(19):1419-1429. PubMed PMID: 27682883.

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2016 Name Marlous Kortekaas PhD defense September 29th, 2016 PhD team de Wit, Hoes, Bartelink Speciality General Practice Position General Practitioner, assistant professor Department General Practice, Julius Center for Health Sciences and Primary Care Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “Zou je dat nou wel laten?”

MAIN PAPER Kortekaas MF, Bartelink ME, Zuithoff NP, van der Heijden GJ, de Wit NJ, Hoes AW. Does integrated training in evidence-based medicine (EBM) in the general practice (GP) specialty training improve EBM behaviour in daily clinical practice? A cluster randomised controlled trial. BMJ Open. 2016 Sep 13;6(9):e010537. PubMed PMID: 27625052.

2016 Name Kay Yin Leung PhD defense June 27th, 2016 PhD team Kretzschmar, Diekman Speciality Epidemiology of infectious disease Position Postdoctoral Researcher Department Mathematics Location Stockholm University City Stockholm Country Sweden Quote “All models are wrong, but some models are useful.“ MAIN PAPER Leung KY, Kretzschmar M. Concurrency can drive an HIV epidemic by moving R0 across the epidemic threshold. AIDS. 2015 Jun 1;29(9):1097-103. PubMed PMID: 25870987.

318 20 years Julius Center; 1996-2017

2016 Sander van der Laan Name PhD defense October 13th, 2016 PhD team De Bakker Speciality Cardiovascular genetics Position Postdoctoral Researcher Department Experimental Cardiology, Divison Heart & Lungs Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “I don’t have dreams; I have goals.”

MAIN PAPER van der Laan SW, Fall T, Soumaré A, Teumer A, Sedaghat S, Baumert J, et al. Cystatin C and Cardiovascular Disease: A Mendelian Randomization Study. J Am Coll Cardiol. 2016 Aug 30;68(9):934-45.

PubMed PMID: 27561768.

2016 Name Margaretha Minnaard PhD defense January 21st, 2016 PhD team de Wit, Verheij, van de Pol, Broekhuijzen Speciality General Practice Position General Practitioner Department Location Various General Practices City Utrecht Country The Netherlands Quote “Life is short, [the] art long, opportunity fleeting, experiment dangerous, judgment difficult.”

- Hippocrates MAIN PAPER Minnaard MC, de Groot JA, Hopstaken RM, Schierenberg A, de Wit NJ, Reitsma JB,et al. The added value of C-reactive protein measurement in diagnosing pneumonia in primary care: a meta-analysis of individual patient data. CMAJ. 2016 Sep 19.

PubMed PMID: 27647618.

20 years Julius Center; 1996-2017 319

2016 Annelies Nijdam Name PhD defense January 26th, 2016 PhD team van der Schouw, Fischer Speciality Epidemiology of Cancer Position Postdoctoral Researcher Department Psychosocial Research and Epidemiology Location Netherlands Cancer Institute City Amsterdam Country The Netherlands Quote “Il n’y a pas de vérité, mais seulement une perception. / There is no truth. There is only perception.”

- Gustave Flaubert, 1821-1880 MAIN PAPER Nijdam A, Foppen W, De Kleijn P, Mauser-Bunschoten EP, Roosendaal G, van Galen KP, et al. Discontinuing early prophylaxis in severe haemophilia leads to deterioration of joint status despite low bleeding rates. Thromb Haemost. 2016 May 2;115(5):931-8. PubMed PMID: 26791021.

2016 Name Stavros Nikolakopoulos PhD defense September 21st, 2016 PhD team Roes, Moons, van der Tweel Speciality Biostatistics Position Assistant Professor Department Biostatistics, Julius Center for Health Sciences and Primary Care Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “Uncertain knowledge + knowledge of the amount of uncertainty= useful knowledge” C.R. Rao MAIN PAPER Nikolakopoulos S, Roes KC, van der Tweel I. Sequential designs with small samples: Evaluation and recommendations for normal responses. Stat Methods Med Res. 2016 Jun 24. PubMed PMID: 27342574.

320 20 years Julius Center; 1996-2017

2016 Welling Oei Name PhD defense January 21th, 2016 PhD team Coutinho, Zaaijer, Kretzschmar, Janssen Speciality Clinical Epidemiology Assistant Professor of Epidemiology Position Department Clinical Epidemiology, Julius Center for Health Sciences and Primary Care Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “The better one does, the less it shows “ MAIN PAPER Oei W, Lieshout-Krikke RW, Kretzschmar ME, Zaaijer HL, Coutinho RA, Eersel M, et al. Estimating the risk of dengue transmission from Dutch blood donors travelling to Suriname and the Dutch Caribbean. Vox Sang. 2016 May;110(4):301-9. PubMed PMID: 26765798.

2016 Name Judith Poldervaart PhD defense February 18th, 2016 PhD team Hoes Doevendans, Reistma, Six Speciality General practice Position Resident in General Practice Department General Practice, Julius Center for Health Sciences and Primary Care Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “Keep calm and calculate the HEART score” MAIN PAPER Poldervaart JM, Langedijk M, Backus BE, Dekker IM, Six AJ, Doevendans PA, Hoes AW, Reitsma JB. Comparison of the GRACE, HEART and TIMI score to predict major adverse cardiac events in chest pain patients at the emergency department. Int J Cardiol. 2017 Jan 15;227:656-661. PubMed PMID: 27810290.

20 years Julius Center; 1996-2017 321

2016 Name Douwe Postma PhD defense March 1st, 2016 PhD team Bonten, Hoepelman, Ossterheert, van Elden Speciality Infectious Disease Medicine Position Fellow Infectious Disease Medicine Department Internal Medicine and Infectious Diseases Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “…”

MAIN PAPER Postma DF, van Werkhoven CH, Oosterheert JJ, Bonten MJ. Predicting community-acquired pneumonia etiology. Chest. 2013 Dec;144(6):1975-6. PubMed PMID: 24297141.

2016 Name Maurice Pouw PhD defense November 29th, 2016 PhD team Kalkman, Moons, Peelen Speciality Anaesthesiology Position Anaesthesiologist Department Anaesthesiology Location Meander Medical Center City Amersfoort Country The Netherlands Quote “…”

MAIN PAPER Pouw ME, Peelen LM, Lingsma HF, Pieter D, Steyerberg E, Kalkman CJ, Moons KG. Hospital standardized mortality ratio: consequences of adjusting hospital mortality with indirect standardization. PLoS One. 2013 Apr 9;8(4):e59160. PubMed PMID: 23593133.

322 20 years Julius Center; 1996-2017

2016 Name Sara Pulit PhD defense February 12th, 2016 PhD team Bakker Speciality Genetic Epidemiology Position Postdoctoral Researcher Department Neurology Department, Brain Center Rudolf Magnus, & Big Data Institute Location University Medical Center Utrecht & University of Oxford Utrecht & Oxford City Country The Netherlands & United Kingdom Quote “…”

MAIN PAPER Pulit SL, de With SA, de Bakker PI. Resetting the bar: Statistical significance in whole-genome sequencing-based association studies of global populations. Genet Epidemiol. 2017 Feb;41(2):145151. PubMed PMID: 27990689.

2016 Name Evelien ter Riet PhD defense February 4th, 2016 PhD team Hoes, Rutten Speciality Elderly Care Position Resident in Elderly Care Department GERION Location VU University Medical Center Amsterdam City Amsterdam Country The Netherlands Quote “...”

MAIN PAPER van Riet EE, Hoes AW, Limburg A, Landman MA, van der Hoeven H, Rutten FH. Prevalence of unrecognized heart failure in older persons with shortness of breath on exertion. Eur J Heart Fail. 2014 Jul;16(7):772-7. PubMed PMID: 24863953.

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2016 Name Charlotte Rietbergen PhD defense February 12th, 2016 PhD team Hoijtink, Moons, Klugkist Speciality Epidemiology Postdoctoral Researcher & Systematic Reviewer Position Department Methodology and Statistics, Faculty of Social Sciences Utrecht University & Trimbos-institute Location City Utrecht The Netherlands Country Quote “…”

MAIN PAPER Rietbergen C, Klugkist I, Janssen KJ, Moons KG, Hoijtink HJ. Incorporation of historical data in the analysis of randomized therapeutic trials. Contemp Clin Trials. 2011 Nov;32(6):848-55. PubMed PMID: 21729767.

2016 Name Camiel de Roij van Zuidewijn PhD defense February 23rd, 2016 PhD team Ter Wee, Bots, Grooteman, Nubé Internal Medicine Speciality Resident in Internal Medicine Position Department Internal Medicine Location VU University Medical Center Amsterdam City Amsterdam Country The Netherlands Quote “Life is what happens to you while you’re busy making other plans.“ MAIN PAPER Chapdelaine I, Mostovaya IM, Blankestijn PJ, Bots ML, van den Dorpel MA,Lévesque R, et al. CONTRAST nvestigators.. Treatment policy rather than patient characteristics determines convection volume in online post-dilution hemodiafiltration. Blood Purif.

2014;37(3):229-37. PubMed PMID: 24943743.

324 20 years Julius Center; 1996-2017

2016 Name Ary Savitri PhD defense June 1st, 2016 PhD team Grobbee, Uiterwaal Speciality Clinical Epidemiology Postdoctoral Researcher Position Department Clinical Epidemiology, Julius Center for Health Sciences and Primary Care University Medical Center Utrecht Location City Utrecht The Netherlands Country Quote “...”

MAIN PAPER Savitri AI, Yadegari N, Bakker J, van Ewijk RJ, Grobbee DE, Painter RC, Uiterwaal CS, Roseboom TJ. Ramadan fasting and newborn’s birth weight in pregnant Muslim women in The Netherlands. Br J Nutr.

2014 Nov 14;112(9):1503-9. PubMed PMID: 25231606.

2016 Name Tom van Seeters PhD defense April 11th, 2016 PhD team Kappelle, van der Graaf, Biessels, Velthuis Speciality Radiology Resident in Radiology Position Department Radiology Location Gelre Hospital City Apeldoorn Country The Netherlands “Alea iacta est (de teerling is geworpen).“ Quote MAIN PAPER van Seeters T, Biessels GJ, Kappelle LJ, van der Schaaf IC, Dankbaar JW,Horsch AD, et al. Dutch acute stroke study (DUST) investigators.

The Prognostic Value of CT Angiography and CT Perfusion in Acute Ischemic Stroke. Cerebrovasc Dis. 2015;40(5-6):258-69. PubMed PMID: 26484857.

20 years Julius Center; 1996-2017 325

2016 Name Sanja Selakovic PhD defense Juli 5th, 2016 Heesterbeek, de Ruiter PhD team Speciality Ecological and Molecular Epidemiology Position Postdoctoral Researcher Department Faculty of Geosciences Location Utrecht University City Utrecht Country The Netherlands Quote “…”

MAIN PAPER Selakovic S, de Ruiter PC, Heesterbeek H. Infectious disease agents mediate interaction in food webs and ecosystems. Proc Biol Sci. 2014 Jan 8;281(1777):20132709. PubMed PMID: 24403336.

2016 Name Maarten van Smeden PhD defense March 10th, 2016 PhD team Moons, Reitsma, de Groot Speciality Biostatistics Position Assistant Professor Department Biostatistics, Julius Center for Health Sciences and Primary Care Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “In God we trust, all others bring data“ - William Edwards Deming (1900-1993) MAIN PAPER van Smeden M, de Groot JA, Moons KG, Collins GS, Altman DG, Eijkemans MJ, Reitsma JB. No rationale for 1 variable per 10 events criterion for binary logistic regression analysis. BMC Med Res Methodol. 2016 Nov 24;16(1):163. PubMed PMID: 27881078

326 20 years Julius Center; 1996-2017

2016 Name Ingrid Staal PhD defense February 6th, 2016 PhD team Schrijvers, Hermans, van Stel Speciality Nursing Sciences Postdoctoral Researcher Position Department Location Public Health Service (GGD) Zeeland City Goes Country The Netherlands Quote “...”

MAIN PAPER Staal II, van Stel HF, Hermanns JM, Schrijvers AJ. Early detection of parenting and developmental problems in young children: Non-randomized comparison of visits to the well-baby clinic with or without a validated interview. Int J Nurs Stud. 2016 Oct;62:1-10.

PubMed PMID: 27423790.

2016 Name Dewi Stalpers PhD defense September 20th, 2016 Schuurmans, Kaljouw PhD team Nursing Sciences Speciality Advisor & researcher Position Department Dutch Hospital Association & Intensive Care Unit Location Dutch Hospital Association & St. Antonius Hospital Utrecht & Nieuwegein City Country The Netherlands Quote “For the sick it is important to have the best “ - Florence Nightingale, 1855 MAIN PAPER Stalpers D, van der Linden D, Kaljouw MJ, Schuurmans MJ. Using Publicly Reported Nursing-Sensitive Screening Indicators to Measure Hospital Performance: The Netherlands Experience in 2011. Nurs Res. 2016 Sep-Oct;65(5):362-70. PubMed PMID: 27579504.

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2016 Mart Stein Name PhD defense December 13th, 2016 PhD team Kretzschmar, van der Heijden, Buskens, van Steenbergen Speciality Epidemiology of Infectious Diseases Position Postdoctoral Researcher Department Centre for Infectious Disease Control Location National Institute for Public Health and the Environment (RIVM) City Bilthoven Country The Netherlands Quote “...”

MAIN PAPER Stein ML, van Steenbergen JE, Buskens V, van der Heijden PG, Koppeschaar CE,Bengtsson L, Thorson A, Kretzschmar ME. Enhancing Syndromic Surveillance With Online Respondent-Driven Detection. Am J Public Health. 2015 Aug;105(8):e90-7.PubMed PMID: 26066940;

2016 Name Irene Touwen PhD defense September 1st, 2016 PhD team Schuurmans, de Wit, Trappenburg Speciality General Practice Position Resident in General Practice Department General Practice, Julius Center for Health Sciences and Primary Care Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “...”

MAIN PAPER Bos-Touwen ID, Trappenburg JC, van der Wulp I, Schuurmans MJ, de Wit NJ. Patient factors that influence clinicians’ decision making in self-management support: A clinical vignette study. PLoS One. 2017 Feb 6;12(2):e0171251. PubMed PMID: 28166244.

328 20 years Julius Center; 1996-2017

2016 Name Irene van de Vorst PhD defense November 10th, 2016 PhD team Bots, Koek, Vaartjes Speciality Geriatric Medicine Resident in Geriatric Medicine Position Department Geriatric Medicine Onze Lieve Vrouwe Gasthuis Location City Amsterdam Country The Netherlands Quote “To care for those who once cared for us is one of the highest honors” - Walker MAIN PAPER van de Vorst IE, Vaartjes I, Geerlings MI, Bots ML, Koek HL. Prognosis of patients with dementia: results from a prospective nationwide registry linkage study in the Netherlands. BMJ Open. 2015 Oct 28;5(10):e008897. PubMed PMID: 26510729.

2016 Name Xin Wang PhD defense January 12th, 2016 PhD team Bots, Vaartjes Pharmacoepidemiology Speciality Postdoctoral Researcher Position Department Pharmacoepimiology Location Shanghai HENGRUI Pharmaceuticals City Shanghai Country China Quote “...”

MAIN PAPER Wang X, Bots ML, Yang F, Sun J, He S, Hoes AW, et al A comparison of the prevalence and clustering of major cardiovascular risk factors in the Netherlands and China. Eur J Prev Cardiol. 2016 Nov;23(16):1766-1773. PubMed PMID: 27154590.

20 years Julius Center; 1996-2017 329

2016 Name Saskia Weldam PhD defense November 3rd, 2016 Lammers, Schuurmans PhD team Speciality Nursing Sciences in chronic lung disease Position Postdoctoral Researcher Department Division Heart & Lungs, Respiratory Department Location University Medical Center Utrecht City Utrecht Country The Netherlands Quote “Instead of asking ‘what’s the matter’, you should ask a patient: ‘What matters to you?’”

MAIN PAPER Weldam SW, Lammers JW, Heijmans MJ, Schuurmans MJ. Perceived quality of life in chronic obstructive pulmonary disease patients: a cross-sectional study in primary care on the role of illness perceptions. BMC Fam Pract. 2014 Aug 3;15:140. PubMed PMID: 25087008.

2016 Name Indah Widyahening PhD defense September 27th, 2016 PhD team Van der Graaf, van der Heijden Speciality Family Medicine Position Research Coordinator of the Community Medicine Department Department Community Medicine Department Location Faculty of Medicine, University Indonesia City Jakarta Country Indonesia Quote “To achieve something you have never achieved before, you must become someone you have never been before” MAIN PAPER Widyahening IS, van der Graaf Y, Soewondo P, Glasziou P, van der Heijden GJ. Awareness, agreement, adoption and adherence to type 2 diabetes mellitus guidelines: a survey of Indonesian primary care physicians. BMC Fam Pract. 2014 Apr 23;15:72. PubMed PMID: 24755412 330 20 years Julius Center; 1996-2017

Class of

2017

2017 Name: Martine Beeftink PhD defense: February 22, 2017 (Co)Supervisors: prof. P.A.F.M. Doevendans, PhD; prof. M.L. Bots, PhD; M. Voskuil, PhD; W. Spiering, PhD Cardiovascular Epidemiology Speciality: Current position: Arts-assistent Cardiologie, St. Antonius Ziekenhuis, Nieuwegein Quote: The thing that is essential about hypertension is that it be treated Ira M. Grais, MD LinkedIn: www.linkedin.com/in/martine-beeftink-469b297b/ ResearchGate: www.researchgate.net/profile/Martine_Beeftink

TITLE PHD THESIS: Challenges in the management of hypertension and heart failure.

2017 Johanneke van den Berg Name: PhD defense: November 30, 2017 (Co)Supervisors: prof. F.L.J. Visseren, PhD; prof. Y. van der Graaf, PhD Speciality: Epidemiology Current position: AIOS Anestesiology, VUmc Amsterdam Quote: â&#x20AC;Ś www.linkedin.com/in/johanneke-van-den-berg LinkedIn: ResearchGate: www.researchgate.net/profile/Johanneke_Van_ Den_Berg

TITLE PHD THESIS: Classical risk factors and identification of patients at (very) high risk of cardiovascular disease.

334 20 years Julius Center; 1996-2017

TITLE PHD THESIS: Resistant hypertension: consequences and treatment options.

RESISTANT HYPERTENSION consequences and treatment options

2017 Esther de Beus Name: June 29, 2017 PhD defense: (Co)Supervisors: prof. M.C. Verhaar, PhD; prof. M.L. Bots, PhD; P.J. Blankestijn, PhD Speciality: Cardiovascular Epidemiology Current position: Internist-nephrologist, Erasmus MC, Rotterdam Quote: Never confuse a single defeat with a final defeat.

(F. Scott Fitzgerald) LinkedIn: www.linkedin.com/in/esther-de-beus-8403622a ResearchGate: www.researchgate.net/profile/Esther_De_Beus

Resistant Hypertension consequences and treatment options

Uitnodiging voor het bijwonen van de verdediging van het proefschrift

Resistant Hypertension consequences and treatment options

door

Esther de Beus donderdag 29 juni 2017 om 10.30 uur Academiegebouw Domplein 29 Utrecht Receptie na afloop

Paranimfen Karlijn Bartelet karlijnbartelet@hotmail.com Susanne de Beus sdbeus@gmail.com

esther de beus

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2017 Name: Frederieke van den Bos PhD defense: September 28, 2017 (Co)Supervisors: prof. Y.T. van der Schouw, PhD; M.H. Emmelot-Vonk, PhD; H.J.J. Verhaar, PhD Speciality: Cardiovascular Epidemiology Current position: …

Quote: …

LinkedIn: …

ResearchGate: …

TITLE PHD THESIS: Comorbidities in Parkinson’s disease, cause or consequence?

20 years Julius Center; 1996-2017 335

Esther de Beus

esther de beus

Vleutenseweg 271H 3532 HE Utrecht estherdebeus@gmail.com 06-22299857

29/05/2017 14:09

2017 Name: Boon How Chew PhD defense: December 13, 2017 (Co)Supervisors: prof. G.E.H.M. Rutten, PhD; R.C. Vos, PhD Speciality: General Practice Current position: Associate Professor & Family Medicine Specialist, Department of Family Medicine, Faculty of Medicine and Health Sciences, University Putra Malaysia Quote: …

LinkedIn: www.linkedin.com/in/boon-how-chew-80151b6 ResearchGate: www.researchgate.net/profile/Boon_How_ Chew2

TITLE PHD THESIS: Handling emotional distress in Malaysian adults with type 2 diabetes.

2017 Name: Jeroen Dikken PhD defense: June 20, 2017 (Co)Supervisors: prof. M.J. Schuurmans, PhD; J.G. Hoogerdujin, PhD Speciality: Methodology Current position: Senior lecturer (Hogeschoolhoofddocent) in Nursing, Faculty of Health, Nutrition & Sport, University of applied sciences The Hague Quote: Why when you squeeze an orange as hard as you can squeeze it, does orange juice comes out?

Because that’s what inside! www.linkedin.com/in/jeroen-dikken-83230765/ LinkedIn: ResearchGate: www.researchgate.net/profile/Jeroen_Dikken

TITLE PHD THESIS: How to measure nurses’ knowledge and attitude regarding older patients?

336 20 years Julius Center; 1996-2017

2017 Name: Sander van Doorn PhD defense: September 28, 2017 (Co)Supervisors: prof. K.G.M. Moons, PhD; prof. A.W. Hoes, PhD; G.J. Geersing, PhD; F.H. Rutten, PhD Speciality: Cardiovascular Epidemiology Current position: General practitioner at Gezondheidscentra Maarssenbroek Quote: …

LinkedIn: www.linkedin.com/in/sander-van-doorn635aaa94 ResearchGate: www.researchgate.net/profile/Sander_Van_ Doorn2

TITLE PHD THESIS: Risk management of patients with atrial fibrillation in general practice

2017 Name: Ingeborg de Goeij - van der Meulen PhD defense: August 31, 2017 (Co)Supervisors: prof. R. Koole, PhD; W.J.G. Ros, PhD; A.M. May de Groot, PhD Speciality: PHM Current position: Teacher / researcher,University of applied sciences Groningen Quote: …

LinkedIn: www.linkedin.com/in/ingeborg-c-van-der-meulen-de-goeij-35395924 ResearchGate: …

TITLE PHD THESIS: Nurse-led psychosocial interventions in follow-up care for Head and Neck cancer patients.

20 years Julius Center; 1996-2017 337

2017 Name: Gulmisal Güder April 11, 2017 PhD defense: (Co)Supervisors: prof. A.W. Hoes, PhD; prof. S. Störk, PhD; F.H. Rutten, PhD Cardiovascular Epidemiology Speciality: Current position: …

Quote: …

LinkedIn: …

ResearchGate: …

TITLE PHD THESIS: Ventilatory disorders in heart failure.

2017 Name: Tanya Guryeva PhD defense: December 5, 2017 (Co)Supervisors: prof. M.J.M. Bonten, PhD; M.C.J. Bootsma, PhD Infectious diseases Speciality: Current position: …

Quote: … …

LinkedIn: ResearchGate: …

TITLE PHD THESIS: Mathematical studies on nosocomial spread of antibiotic-resistant bacteria.

338 20 years Julius Center; 1996-2017

2017 Floor Haalboom Name: September 21, 2017 PhD defense: (Co)Supervisors: prof. F.G. Huisman, PhD; prof. P.A. Koolmees, PhD Speciality: PHM Current position: Teacher and researcher, department Medical History, Erasmus MC, Rotterdam; post doc researcher, Descartes Center for the History and Philosophy of the Sciences and the Humanities, Utrecht University Quote: We need history to understand our present and our future.

LinkedIn: www.linkedin.com/in/floor-haalboom-84739763 ResearchGate: â&#x20AC;Ś

TITLE PHD THESIS: Negotiating zoonoses: Dealings with infectious diseases shared by humans and livestock in The Netherlands (1898-2001).

2017 Name: Eva Hendriks PhD defense: March 28, 2017 (Co)Supervisors: prof. Y.T. van der Schouw, PhD; prof. P.A. de Jong, PhD; J.W.J. Beulens; PhD Speciality: Cardiovascular Epidemiology Current position: Huisarts in opleiding, SBOH/UMC Utrecht Quote: Wisdom begins in wonder.

LinkedIn: www.linkedin.com/in/eva-hendriks-80061729/ ResearchGate: www.researchgate.net/profile/Eva_Hendriks

TITLE PHD THESIS: Medial arterial calcification: novel insights into its determinants and cardiovascular implications.

20 years Julius Center; 1996-2017 339

2017 Name: Loan van Hoeven PhD defense: June 29, 2017 (Co)Supervisors: prof. C.B. Roes, PhD; M.P. Janssen, PhD; H. Koffijberg, PhD Speciality: Methodology Current position: Post-doc researcher, Sanquin Quote: …

LinkedIn: …

ResearchGate: …

Transfusion

d ata :

TITLE PHD THESIS: Transfusion data: from collection to reflection.

from collection to reflection

Loan R. van Hoeven

Loan R. van Hoeven

2017 Name: Agnetha Hofhuis PhD defense: November 2, 2017 (Co)Supervisors: prof. R.A. Coutinho, PhD; W. van Pelt, PhD; H. Sprong, PhD Infectious diseases Speciality: Current position: …

Quote: … …

LinkedIn: ResearchGate: …

TITLE PHD THESIS: Epidemiology of Lyme borreliosis and other tick-borne diseases in the Netherlands.

340 20 years Julius Center; 1996-2017

2017 Rosa de Jager Name: June 27, 2017 PhD defense: (Co)Supervisors: prof.M.L. Bots, PhD; prof. M.C. Verhaar, PhD; P.J. Blankestijn, PhD Speciality: Cardiovascular Epidemiology Current position: …

Quote: …

LinkedIn: …

ResearchGate: …

TITLE PHD THESIS: Renal denervation: under pressure?

2017 Name: Victor Jong PhD defense: May 23, 2017 (Co)Supervisors: prof. M.J.C. Eijkemans, PhD; prof. C.B. Roes, PhD Speciality: Methodology Current position: Senior Data Scientist, Capgemini Quote: We are drowning in data yet starving for knowledge - ERIC D. BROWN LinkedIn: www.linkedin.com/in/victor-lih-jong-85974066/ ResearchGate: www.researchgate.net/profile/Victor_Jong Predicting an optimal function for diagnostic and prognostic analyses with gene expression data

TITLE PHD THESIS: Predicting an optimal function for diagnostic and prognostic analyses with gene expression data.

Victor Lih Jong

20 years Julius Center; 1996-2017 341

2017 Name: Shona Kalkman PhD defense: March 2, 2017 (Co)Supervisors: prof. J.J.M. van Delden, PhD; prof. D.E. Grobbee, PhD; G.J.M.W. van Thiel, PhD Speciality: Methodology Current position: …

Quote: …

LinkedIn: www.linkedin.com/in/shona-kalkman438b69100/ ResearchGate: …

TITLE PHD THESIS: Pragmatic randomized trials with new interventions: An ethical analysis.

2017 Name: Annelien de Kat PhD defense: May 11, 2017 (Co)Supervisors: prof. F.J.M. Broekmans, PhD; prof. Y.T. van der Schouw, PhD Cardiovascular Epidemiology Speciality: Current position: AIOS gynaecologie Quote: … www.linkedin.com/in/annelien-de-kat-aaab2a59 LinkedIn: ResearchGate: www.researchgate.net/profile/Annelien_De_Kat

TITLE PHD THESIS: Female Aging - Quantification of ovarian reserve and its association with cardiovascular health.

342 20 years Julius Center; 1996-2017

2017 Charlotte Koopal Name: April 13, 2017 PhD defense: (Co)Supervisors: prof. F.L.J. Visseren, PhD; prof. Y. van der Graaf, PhD; J. Westerink, PhD Speciality: Cardiovascular Epidemiology Current position: …

Quote: …

LinkedIn: www.linkedin.com/in/charlotte-koopal-8257272b/ ResearchGate: www.researchgate.net/profile/Charlotte_Koopal

TITLE PHD THESIS: Genetic lipid disorders. Familial Dysbetalipoproteinemia and cardiovascular disease.

2017 Name: Pauline Kouwenhoven PhD defense: December 7, 2017 (Co)Supervisors: prof. J.J.M. van Delden, PhD; prof. A. van der Heide, PhD; G.J.M. van Thiel, PhD; J.A.C. Rietjens, PhD Speciality: PHM Current position: …

Quote: …

LinkedIn: …

ResearchGate: …

TITLE PHD THESIS: Knowledge and opinions of health care professionals and the public about end-of-life decisions.

20 years Julius Center; 1996-2017 343

2017 Name: Anne Kuijer PhD defense: October 26, 2017 (Co)Supervisors: prof. I.H.M. Borel-Rinkes, PhD; prof. M.A.A.J. Bosch, PhD; Th. van Dalen, PhD; S.G. Elias, PhD Speciality: Epidemiology Current position: Arts-assistent Chirurgie Diakonessenhuis, Utrecht Quote: …

LinkedIn: www.linkedin.com/in/akuijer/ ResearchGate: www.researchgate.net/profile/Anne_Kuijer2

Pieterbas Lalleman

on daily work and habitus of nurse middle managers in hospitals

TITLE PHD THESIS: Interplay Between Gene Expression Profiling and Adjuvant Systemic Therapy Decision-Making in Early Stage Breast Cancer.

2017 Name: Pieterbas Lalleman PhD defense: November 16, 2017 (Co)Supervisors: prof. M.J. Schuurmans, PhD; prof. G.A.C. Smid, PhD Speciality: PHM Current position: University of Applied Sciences Utrecht, Clinical Health Sciences / Julius Center Quote: Investigative, entrepreneurial and curious with a strong belief in the craft of clinical leadership as driver for high quality patient care. // “The difficulty, in Sociology, is to manage to think in a completely astonished and disconcerted way about things you thought you had always understood.” - Pierre Bourdieu – www.linkedin.com/in/pieterbaslalleman/ LinkedIn: ResearchGate: www.researchgate.net/profile/Pieterbas_Lalleman

TITLE PHD THESIS: Leadership as blended care: on daily work and habitus of nurse middle managers in hospitals.

344 20 years Julius Center; 1996-2017

2017 Marije Lamain-de Ruiter Name: June 22, 2017 PhD defense: (Co)Supervisors: prof. A. Franx, PhD; prof. K.G.M. Moons, PhD; M.P.H. Koster, PhD; A. Kwee, PhD Speciality: Methodology Current position: Midwife, Wilhelmina Children’s Hospital, Utrecht Quote: …

LinkedIn: www.linkedin.com/in/marije-lamain-de-ruiter424b73a0 ResearchGate: www.researchgate.net/profile/Marije_ Lamain-De_Ruiter

TITLE PHD THESIS: What to expect when you’re expecting?

2017 Name: Virissa Lenters PhD defense: September 19, 2017 (Co)Supervisors: prof. D.J.J. Heederik, PhD; prof. A.H. Piersma, PhD; R.C.H. Vermeulen, PhD; L. Portengen, PhD Speciality: Environmental Epidemiology Current position: …

Quote: …

LinkedIn: www.linkedin.com/in/virissa-lenters-488672a/ ResearchGate: www.researchgate.net/profile/Virissa_Lenters

TITLE PHD THESIS: Assessing our multi-pollutant burden: environmental chemical exposures and reproductive and child health.

20 years Julius Center; 1996-2017 345

2017 Name: Jaike Praagman PhD defense: June 1, 2017 (Co)Supervisors: prof. Y.T. van der Schouw, PhD; J.W.J. Beulens, PhD; I. Sluijs, PhD Cardiovascular Epidemiology Speciality: Current position: …

Quote: …

LinkedIn: www.linkedin.com/in/jaikepraagman/ ResearchGate: …

TITLE PHD THESIS: Dietary fatty acids and cardiovascular disease risk in observational studies.

2017 Margreet Sanders Name: PhD defense: October 26, 2017 (Co)Supervisors: prof. M.L. Bots, PhD; prof. M.C. Verhaar, PhD; P.J. Blankestijn, PhD Cardiovascular Epidemiology Speciality: Current position: …

Quote: … …

LinkedIn: ResearchGate: …

TITLE PHD THESIS: Renal denervation: studies into short and long term effectiveness and safety.

346 20 years Julius Center; 1996-2017

2017 Maartje Schouten Name: March 23, 2017 PhD defense: (Co)Supervisors: prof. E.E.S. Nieuwenhuis, PhD; prof. Th.J.M. Verheij, PhD; E.M. van de Putte, PhD; H.F. van Stel, PhD Speciality: Methodology Current position: …

Quote: …

LinkedIn: www.linkedin.com/in/maartje-schouten-748007108/ ResearchGate: …

TITLE PHD THESIS: Systematic screening for child abuse in out-of-hours primary care.

2017 Name: Manon Slob PhD defense: March 9, 2017 (Co)Supervisors: prof. F.L.J. Visseren, PhD; prof. Y. van der Graaf, PhD Speciality: Cardiovascular Epidemiology Current position: …

Quote: …

LinkedIn: …

ResearchGate: …

TITLE PHD THESIS: Individualized cardiovascular disease prevention in clinical practice.

Estimation of treatment benefit and cost.

20 years Julius Center; 1996-2017 347

2017 Name: David Speksnijder PhD defense: April 25, 2017 (Co)Supervisors: prof. J.A. Wagenaar, PhD; prof. Th.J.M. Verheij, PhD Infectious diseases Speciality: Current position: Researcher, Faculty of Veterinary Medicine, Utrecht University Quote: …

LinkedIn: www.linkedin.com/in/david-speksnijder­ 00548926/?ppe=1 ResearchGate: www.researchgate.net/profile/David_ Speksnijder

TITLE PHD THESIS: Antibiotic use in farm animals. Supporting behavioural change of veterinarians and farmers.

2017 Name: Julien Tanniou PhD defense: June 29, 2017 (Co)Supervisors: prof. C.B. Roes, PhD; I. van der Tweel, PhD Speciality: Methodology Current position: …

Quote: …

LinkedIn: www.linkedin.com/in/julien-tanniou-76950414a/ ResearchGate: …

TITLE PHD THESIS: To lump or to split? Statistical evidence of subgroup findings in confirmatory clinical trials and the regulatory perspective.

348 20 years Julius Center; 1996-2017

2017 Jolien Teepe Name: June 20, 2017 PhD defense: (Co)Supervisors: prof. Th.J.M. Verheij, PhD; prof. H. Goossens, PhD; B.D.L. Broekhuizen, PhD Speciality: Infectious diseases Current position: …

Quote: …

LinkedIn: www.linkedin.com/in/jolien-teepe-439185110/ ResearchGate: www.researchgate.net/profile/Jolien_Teepe

TITLE PHD THESIS: Bacterial aetiology in lower respiratory tract infection Relevance in outpatients.

2017 Name: Mark Valk PhD defense: October 24, 2017 (Co)Supervisors: prof. A.W. Hoes, PhD; F.H. Rutten, PhD; A. Mosterd, PhD Speciality: Cardiovascular Epidemiology Current position: Huisarts in de praktijk Valk/Meijer,Amersfoort Quote: …

LinkedIn: www.linkedin.com/in/mark-valk-b1594694/ ResearchGate: …

TITLE PHD THESIS: Heart Failure Care in General Practice.

20 years Julius Center; 1996-2017 349

Preoperative exercise training to improve postoperative outcomes – Karin Valkenet

2017 Name: Karin Valkenet PhD defense: April 6, 2017 (Co)Supervisors: prof. F.J.G. Backx, PhD; prof. R. van Hillegersberg, PhD; J.C.A. Trappenburg, PhD Speciality: Methodology Current position: Senior researcher Physiotherapy Sciences and Program mananager “UMC Utrecht in Beweging” , Rehabilitation, Physiotherapy Sciences and Sport, UMC Utrecht Quote: …

LinkedIn: www.linkedin.com/in/karin-valkenet-0b74723a/ ResearchGate: www.researchgate.net/profile/Karin_Valkenet

TITLE PHD THESIS: Preoperative exercise training to improve postoperative outcomes.

2017 Lisa Verberne Name: PhD defense: August 31, 2017 (Co)Supervisors: prof. J.J.M. van Delden, PhD; prof. M.A. Grootenhuis, PhD; M.C. Kars, PhD; D.K. Bosman, PhD Speciality: PHM Current position: ANIOS Kindergeneeskunde, WKZ, UMC Utrecht Quote: Een goede voorbereiding is het halve werk www.linkedin.com/in/lisa-verberne-84765584/ LinkedIn: ResearchGate: www.researchgate.net/profile/Lisa_Verberne

TITLE PHD THESIS: The value of case management in paediatric palliative care.

350 20 years Julius Center; 1996-2017

2017 Kim Wagenaar Name: March 23, 2017 PhD defense: (Co)Supervisors: prof. A.W. Hoes, PhD; prof. T. Jaarsma, PhD; F.H. Rutten, PhD; B.D.L. Broekhuizen, PhD Speciality: Methodology Current position: Scientific Advisor at the European Association of Preventive Cardiology / European Society of Cardiology Quote: …

LinkedIn: www.linkedin.com/in/kim-wagenaar-79a47a11/ ResearchGate: …

TITLE PHD THESIS: E-health in heart failure.

2017 Name: Hanneke Wanders PhD defense: June 22, 2017 (Co)Supervisors: prof. P.H.M. Peeters, PhD; prof. N. Karssemeijer, PhD; C.H. van Gils, PhD Speciality: Cancer Current position: …

Quote: Honesty is the best policy LinkedIn: …

ResearchGate: …

TITLE PHD THESIS: Automatically assessed volumetric breast density and breast cancer risk: The era of digital screening mammography.

20 years Julius Center; 1996-2017 351

2017 Name: Indira van der Zande PhD defense: December 14, 2017 (Co)Supervisors: prof. J.J.M. van Delden, PhD; R. van der Graaf, PhD; M.A. Oudijk, PhD Speciality: PHM Current position: Education Coordinator, Rijksuniversiteit Groningen/Campus Fryslân Quote: …

LinkedIn: www.linkedin.com/in/indira-van-derzande-a807171a/ ResearchGate: www.researchgate.net/profile/Indira_Van_ Der_Zande

TITLE PHD THESIS: Fair Inclusion of Pregnant Women in Clinical Research.

352 20 years Julius Center; 1996-2017

20 years Julius Center; 1996-2017 353

Colophon EDITION Julius Center

PHOTOGRAPHY cover: Hannie Rieuwerts (http://www.aquarieuwerts.nl/) DESIGN Henriëtte van der Louw, Design & Producties EDITORIAL Koen, Michiel and Sophie Bots PRINTER REVON Drukkerij BV, Woerden

UMC Utrecht, January 2018

Julius Center Visiting address Universiteitsweg 100, 3584 CG Utrecht The Netherlands Postal Address POBox 85500 Huispostnr. str.6.131 3508 GA Utrecht The Netherlands T.: +31(0)88 75 681 81 Email: JuliusCenter@umcutrecht.nl www.juliuscenter.nl

UMC Utrecht Julius Center