Say you saw it in the Beacon | Fitness & Health
WA S H I N G T O N B E A C O N — J U N E 2 0 1 4
FOR ADULTS WITH DUPUYTREN’S CONTRACTURE WHEN A “CORD” CAN BE FELT
YOU MAY HAVE MORE OPTIONS THAN YOU THINK, AND THAT’S
NO SMALL THING XIAFLEX FOR INJECTION
ASK YOUR DOCTOR IF SOMETHING NONSURGICAL CAN BE DONE NOW Dupuytren’s contracture is a disorder of the hand that can worsen over time. XIAFLEX is the only FDA-approved therapy that is administered during an in-office nonsurgical procedure to treat Dupuytren’s contracture where a “rope-like” cord can be felt. A hand specialist trained to inject XIAFLEX performs the procedure, and no general anesthesia is required for administration. Studies show that prescription XIAFLEX may help straighten the affected finger and improve range of motion. These results have been shown in contractures ranging from less severe to more severe. And that’s no small thing. In two clinical studies, 64% and 44% of people receiving XIAFLEX (versus 7% and 5% of patients receiving placebo) had a straight or nearly straight finger after up to 3 XIAFLEX injection procedures. Most people required 1 or 2 injection procedures with XIAFLEX to help “break” the cord. Since February 2010, approximately 45,000 people have had their Dupuytren’s contracture treated with XIAFLEX. Watch a video about one person’s treatment experience, and find more information at XIAFLEX.com. Then, talk with your doctor to see if XIAFLEX may be right for you.
IMPORTANT SAFETY INFORMATION Do not receive XIAFLEX if you have had an allergic reaction to collagenase clostridium histolyticum or any of the ingredients in XIAFLEX, or to any other collagenase product. XIAFLEX can cause serious side effects including tendon rupture (break), ligament damage, nerve injury or other serious injury of the hand, or allergic reaction. Surgery could be required to fix the damaged tendon or ligament. Call your doctor right away if you have trouble bending your injected finger after the swelling goes down, pain, tingling, numbness, or problems using your treated hand or if you get hives, swollen face, breathing trouble, or chest pain. Bleeding or bruising at the injection site can happen in people who receive XIAFLEX. It’s important to tell your doctor about a prior allergic reaction to XIAFLEX, or if you have a bleeding problem or use a blood thinner. Common side effects include hand swelling, bruising, injection site reaction or bleeding, and pain. XIAFLEX should be injected into the cord by a healthcare provider who is experienced in injection procedures of the hand and treating people with Dupuytren’s contracture. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
Please see Important Product Information on the following page.
Find a XIAFLEX-experienced hand specialist near you. Use the Physician Locator tool at XIAFLEX.com.
© 2014 Auxilium Pharmaceuticals, Inc. All rights reserved. XDC-00721 April 2014
FOR MORE INFORMATION, CALL 1-877-XIAFLEX
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