JUNE 4TH Anniversary Issue

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Statins Deregulate the Endocannabinoid System



The Endocannabinoid system (ECS) is a biological system found in all mammals that play a role in regulating a wide range of physiological processes, including pain, mood, appetite, and immune function. The ECS is made up of three main components: endocannabinoids, receptors, and enzymes.

Endocannabinoids are molecules that are similar in structure to the compounds found in the cannabis plant, known as cannabinoids. The two main endocannabinoids in the body are anandamide and 2-arachidonoylglycerol (2-AG). These molecules are produced by the body on-demand and are not stored in advance. Receptors are proteins that are found on the surface of cells throughout the body. The two main receptors in the ECS are

CB1 and CB2. CB1 receptors are primarily found in the central nervous system, while CB2 receptors are primarily found in the immune system and other peripheral tissues.

The third component of the ECS are enzymes, which are responsible for breaking down endocannabinoids once they have fulfilled their function. These enzymes are responsible for maintaining the balance of the ECS.

The ECS works by regulating the balance of many different physiological processes in the body. When something is out of balance, such as chronic pain or anxiety, endocannabinoids are produced to help restore balance. The endocannabinoids interact with the receptors in the body to help regulate the process that is out of balance. For example, if you have chronic pain, endocannabinoids will bind to the receptors responsible for pain management and reduce the sensation of pain.

This system allows the body to respond to changes in its environment and internal conditions, such as injury or disease, by restoring balance and homeostasis, thereby helping to prevent or reduce symptoms.

Cannabis and its derivatives, especially whole plant CBD and THC, interact with the ECS and can provide therapeutic benefits. They can interact with the receptors and mimic or enhance the effects of the endocannabinoids already present in the body.

All information in this article is for educational purposes only. Please check with your Cannabis Educated Primary Health Care Physician or Cannabis Therapy Consultant before beginning any new diet or lifestyle change. ~Dr. Pepper Hernandez

Dr. Pepper Hernandez ND, Ph.D. is a Naturopathic Nutritionist, Board Certified Holistic Health Practitioner, Cannabis Therapy Consultant & Cannabis Holistic Institute Founder and Educational Director. To find out more about her private practice, educational programs, videos and other offerings you can find her on the massive interwebs at drpepperhernandez.com.

Go forth, Go Cannabis

Dr. Pepper Hernandez ND, Ph.D., CTC, CNHP, NHC Board Certified and Award-Winning Holistic Health Practitioner http://DrPepperHernandez.com Office Appointments 1.800.420.9358

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