PENICILLAMINE CAPSULES
Taj Pharmaceuticals Ltd India | Taj Pharma | Taj Pharmaceuticals Mumbai, Company Overview of Taj Pharmaceuticals Limited |Taj Pharmaceuticals Limited Taj Pharmaceutical an Industrial conglomerate, having diversified interest in
Pharmaceuticals and healthcare, Chemicals, API and Agro commodities mainly offers unique opportunities for all its associates to grow in capacity as one of a significant part in curing lives worldwide and building a disease-free nation. Taj Pharma is having more than 600+ brands in different divisions and multiple
subsidiaries to meet up most of the requirements of buyers in our industry along with a very efficient staff management capacity.
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TABLE OF CONETNTS
About Taj Pharma About Penicillamine Composition Available Marketed Products Indications Mechanism of Action Method of Administration Uses Conclusion and Future prospects
Taj Pharmaceuticals Ltd India | Taj Pharma | Taj Pharmaceuticals Mumbai, Company Overview of Taj Pharmaceuticals Limited |Taj Pharmaceuticals Limited Taj Pharmaceutical an Industrial conglomerate, having diversified interest in Pharmaceuticals and healthcare, Chemicals, API and Agro commodities mainly offers unique opportunities for all its associates to grow in capacity as one of a significant part in curing lives worldwide and building a disease-free nation. Taj Pharma is having more than 600+ brands in different divisions and multiple subsidiaries to meet up most of the requirements of buyers in our industry along with a very efficient staff management capacity.
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ABOUT TAJ PHARMA • Taj Pharmaceuticals Limited manufactures and distributes medicines. • The company’s products include prescription solutions, lifesaving drugs, anti-cancer drugs, veterinary products, consumer brands, and CNS drugs. • It focuses on medicines of anemia, anxiety disorders, cancer/oncology, ear infections, heart failure, hepatitis, HIV/AIDS, influenza, non-Hodgkin’s lymphoma, obesity, osteoporosis, Parkinson’s disease, pneumonia, transplantation, and common diseases. • Taj Pharmaceuticals Limited was founded in 2004 and is headquartered in Mumbai, India Taj Pharmaceuticals Ltd India | Taj Pharma | Taj Pharmaceuticals Mumbai, Company Overview of Taj Pharmaceuticals Limited |Taj Pharmaceuticals Limited Taj Pharmaceutical an Industrial conglomerate, having diversified interest in Pharmaceuticals and healthcare, Chemicals, API and Agro commodities mainly offers unique opportunities for all its associates to grow in capacity as one of a significant part in curing lives worldwide and building a disease-free nation. Taj Pharma is having more than 600+ brands in different divisions and multiple subsidiaries to meet up most of the requirements of buyers in our industry along with a very efficient staff management capacity.
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ABOUT PENICILLAMINE
Penicillamine is an anti-rheumatic agent used in the treatment of Rheumatoid Arthritis. It is known as disease modifying anti-rheumatic drug (DMARD). It is also classified as metal chelating agent due to its metal binding capacity, which is used in the treatment of Wilson’s disease, in which copper accumulates in the body. Rheumatoid Arthritis is an autoimmune disorder which causes severe inflammation of joints. Mechanism of action of penicillamine to treat Rheumatoid Arthritis is unknown, but it might be reducing the formation of collagen and also in suppression of immune system ultimately in reduction of inflammation. Taj Pharmaceuticals Ltd India | Taj Pharma | Taj Pharmaceuticals Mumbai, Company Overview of Taj Pharmaceuticals Limited |Taj Pharmaceuticals Limited Taj Pharmaceutical an Industrial conglomerate,
Ref: https://medlineplus.gov/druginfo/meds/a618021.html
having diversified interest in Pharmaceuticals and healthcare, Chemicals, API and Agro commodities mainly offers unique opportunities for all its associates to grow in capacity as one of a significant part in curing lives worldwide and building a disease-free nation. Taj Pharma is having more than 600+ brands in different divisions and multiple subsidiaries to meet up most of the requirements of buyers in our industry along with a very efficient staff management capacity.
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COMPOSITION Each hard gelatin capsule contains: Penicillamine 250 mg
Taj Pharmaceuticals Ltd India | Taj Pharma | Taj Pharmaceuticals Mumbai, Company Overview of Taj Pharmaceuticals Limited |Taj Pharmaceuticals Limited Taj Pharmaceutical an Industrial conglomerate, Image ref: https://tajgenerics.com/wp-content/uploads/penicillamine-250-mg-capsules-2.jpg having diversified interest in Pharmaceuticals and healthcare, Chemicals, API and Agro commodities mainly offers unique opportunities for all its associates to grow in capacity as one of a significant part in curing lives worldwide and building a disease-free nation. Taj Pharma is having more than 600+ brands in different divisions and multiple subsidiaries to meet up most of the requirements of buyers in our industry along with a very efficient staff management capacity.
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AVAILABLE MARKETED PRODUCTS Brand name Cuprimine
Strengths 125 mg, 250 mg
D-penamine, Depen
125 mg, 250 mg
Manufacturers Merck Sharp & Dohme Limited, Merck Ltd., Aton pharma INC. Mylan Pharmaceuticals Inc., MEDA Pharmaceuticals, Carter Horner Corp.
• Zinc administered orally can be used as an alternative to Penicillamine for Wilson’s Disease.
Ref: https://www.drugbank.ca/drugs/DB00859
Taj Pharmaceuticals Ltd India | Taj Pharma | Taj Pharmaceuticals Mumbai, Company Overview of Taj Pharmaceuticals Limited |Taj Pharmaceuticals Limited Taj Pharmaceutical an Industrial conglomerate, having diversified interest in Pharmaceuticals and healthcare, Chemicals, API and Agro commodities mainly offers unique opportunities for all its associates to grow in capacity as one of a significant part in curing lives worldwide and building a disease-free nation. Taj Pharma is having more than 600+ brands in different divisions and multiple subsidiaries to meet up most of the requirements of buyers in our industry along with a very efficient staff management capacity.
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INDICATION
Used in the treatment of Rheumatoid Arthritis Used in the treatment of Wilson’s disease for the removal of excess of copper accumulated in the body
Accumulation of copper in eyeball
Deformity in joints due to Rheumatoid Arthritis
Taj Pharmaceuticals Ltd India | Taj Pharma | Taj Pharmaceuticals Mumbai, Company Overview of Taj Pharmaceuticals Limited |Taj Pharmaceuticals Limited Taj Pharmaceutical an Industrial conglomerate, having diversified interest in Pharmaceuticals and healthcare, Chemicals, API and Agro commodities mainly offers unique opportunities for all its associates to grow in capacity as one of a significant part in curing lives worldwide and building a disease-free nation. Taj Pharma is having more than 600+ brands in different divisions and multiple subsidiaries to meet up most of the requirements of buyers in our
Ref: https://www.webmd.com/drugs/2/drug-7560/penicillamine-oral/details
industry along with a very efficient staff management capacity.
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MECHANISM OF ACTION
Rheumatoid Arthritis: Intereferes with the cross-link formations of tropocollagen molecule when newly formed.Mechanism of action of penicillamine is unknown in rheumatoid arthritis. It lowers the IgM rheumatoid factor but no significant difference in absolute serum immunoglobulin levels. In-vitro suppression of T-cell activity but not B-cell activity. Wilson’s disease: Two molecules of Penicillamine binds with one atom of copper and are excreted out of the body.
Taj Pharmaceuticals Ltd India | Taj Pharma | Taj Pharmaceuticals Mumbai, Company Overview of Taj Pharmaceuticals Limited |Taj Pharmaceuticals Limited Taj Pharmaceutical an Industrial conglomerate, having diversified interest in Pharmaceuticals and healthcare, Chemicals, API and Agro commodities mainly offers unique opportunities for all its associates to grow in capacity as one of a significant part in curing lives worldwide and building a disease-free nation. Taj Pharma is having more than 600+ brands in different divisions and multiple subsidiaries to meet up most of the requirements of buyers in our
Ref: https://www.drugbank.ca/drugs/DB00859
industry along with a very efficient staff management capacity.
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METHOD OF ADMINISTRATION
For Rheumatoid Arthritis, 250 mg once a day dose is usually prescribed. For Wilson’s disease 0.75 g to 1 g dose is usually prescribed.
Taj Pharmaceuticals Ltd India | Taj Pharma | Taj Pharmaceuticals Mumbai, Company Overview of Taj Pharmaceuticals Limited |Taj Pharmaceuticals Limited Taj Pharmaceutical an Industrial conglomerate,
Ref: https://www.webmd.com/drugs/2/drug-7560/penicillamine-oral/details
having diversified interest in Pharmaceuticals and healthcare, Chemicals, API and Agro commodities mainly offers unique opportunities for all its associates to grow in capacity as one of a significant part in curing lives worldwide and building a disease-free nation. Taj Pharma is having more than 600+ brands in different divisions and multiple subsidiaries to meet up most of the requirements of buyers in our industry along with a very efficient staff management capacity.
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USES
Decreased inflammation of joints in case of Rheumatoid Arthritis. Forms metal chelates with copper and mercury, hence used in Wilson’s disease or copper poisoning and mercury poisoning. Used in lead poisoning as an adjuvant to edetate. Used in cystinuria and cystic stones. Used in scleroderma as it increases the soluble collagen
Ref: https:// 3.bp.blogspot.com/tkSuCJDlxjg/VrmN0tYZ9MI/AAAAAAAAArg/VDQFpa9DnGk/s1600/penicillam Taj Pharmaceuticals Ltd India | Taj Pharma | Taj Pharmaceuticals Mumbai, Company Overview of Taj Pharmaceuticals Limited |Taj Pharmaceuticals Limited Taj Pharmaceutical an Industrial conglomerate, having ine%2B250%2Bmg%2Bcapsules%2B%25289%2529.jpg diversified interest in Pharmaceuticals and healthcare, Chemicals, API and Agro commodities mainly offers unique opportunities for all its associates to grow in capacity as one of a significant part in curing lives worldwide and building a disease-free nation. Taj Pharma is having more than 600+ brands in different divisions and multiple subsidiaries to meet up most of the requirements of buyers in our industry along with a very efficient staff management capacity.
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CONCLUSION AND FUTURE PROSPECTS
As no exact mechanism of action is effective in case of rheumatoid arthritis, Penicillamine should be administered along with other anti-rheumatic agents for effective treatment. It is well proven that Penicillamine is a good metal binding agent and has been used for rare disease treatment (Wilson’s Disease). More in-vitro and in-vivo studies should be carried out to study the exact mechanism of action for rheumatoid arthritis at available strengths.
Taj Pharmaceuticals Ltd India | Taj Pharma | Taj Pharmaceuticals Mumbai, Company Overview of Taj Pharmaceuticals Limited |Taj Pharmaceuticals Limited Taj Pharmaceutical an Industrial conglomerate, having diversified interest in Pharmaceuticals and healthcare, Chemicals, API and Agro commodities mainly offers unique opportunities for all its associates to grow in capacity as one of a significant part in curing lives worldwide and building a disease-free nation. Taj Pharma is having more than 600+ brands in different divisions and multiple subsidiaries to meet up most of the requirements of buyers in our industry along with a very efficient staff management capacity.
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