Mechanisms of allergen immunotherapy and surrogate biomarkers of efficacy
Influence of SIT on dendritic cells
Immune deviation from Th2 to Th1 responses
Induction of regulatory T cells (Foxp3+, IL-10+(Tr1), TGF-β and iTR35 cells)
Induction of ‘protective’ IgG antibodies
Suppression of basophil activation (surface markers and DAO)