SHA24/045002

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AUTOTRANSFUSION FOR A BETTER PATIENT OUTCOME … PROBLEM RELATED TO THE TRANSFUSION OF HOMOLOGOUS BLOOD:

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Transfusion reactions: Infections, viruses and most importantly Immunosupression / Immunomodulation Transfusion-related acute lung injury (TRALI) is a serious complication of blood transfusions that is thought to be most commonly caused by a reaction to White Blood Cell antibodies present primarily in the plasma component of blood products • When transfused, these antibodies can sometimes activate a type of White Blood Cell called a granulocyte, which causes plasma to leak into the lungs, creating fluid accumulation, a condition referred to as acute pulmonary edema There is currently no screening test for the prevention of TRALI, and there is no single intervention that can eliminate the risk of TRALI (1: 2000) Sorin XTRA – STRICTLY CONFIDENTIAL

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| AUTOTRAN SFUSION


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