Curriculum Vitae ALICE RICKARD
EDUCATIONAL BACKGROUND: 1975
B.A.
1985
M.S.
PROFESSIONAL POSITIONS 1975-1979 1979-1988 1988- 2005 2005-present
GRANT AWARDS
MEMBERSHIPS (previous and current)
-Microbiology, Southern Illinois University, Carbondale, IL - Dietetics, St. Louis University, St. Louis, MO
Research Technician, Department of Biochemistry, Washington University, St. Louis, MO. Sr. Research Assistant, Department of Pathology, St. Louis University Medical School, St. Louis, MO. Research Associate, Department of Pathology, St. Louis University Medical School, St. Louis, MO Assistant Research Professor, Department of Pathology, St. Louis University Medical School, St. Louis, MO 1995 Interstitial Cystitis Association-Grant Award 1998 National Kidney Foundation of Eastern and Metro East, Inc. 2000 Interstitial Cystitis Association-Grant Award 2001 Roland Quest Memorial Trust Fund of the St. Louis Community Foundation-Grant Funding 2002 Fishbein Family Foundation-Grant Award 2003 SLU-2000 Grant Award 2005 Doisy Fund 2005 2004-2008 Co Investigator NIDDK:NIH Grant 2008 Doisy Fund 2008 2009 Doisy Fund 2009 Interstitial Cystitis Association The American Society for Parenteral and Enteral Nutrition St. Louis University Cancer Center
PUBLICATIONS 1.
Lagunoff, D. and Rickard, A. Evidence for Control of Mast Cell Granule Protease in Situ by Low pH. Exp. Cell Res. 144:353-360 (1983).
2.
Lagunoff, D., Ray, A. and Rickard, A. Effect of Mast Cell Histamine of Inhibiting Histamine Formation in Vivo with Fluoromethyl-histidine. Biochem. Pharm. 34:12051209 (1985).
3.
Lagunoff, D., Rickard, A., Peizner, D., Cinchon, J. and Zarka, M. Flow Cytofluorometric Studies of IgE Binding Sites on Rat Peritoneal Mast Cells. In: Mast Cell Differentiation and Heterogeneity (Ed. A.D. Befus, Raven Press, New York, 1986).
4.
Lagunoff, D., and Rickard, A. Methods for Study of Rat Peritoneal Mast Cell Secretion. In.: In vitro Methods for Studying Secretion (ed. Poisner and Trifaro)., Elsevier Science Publishers, Amsterdam, The Netherlands 1987).
5.
Rickard, A., and Lagunoff, D. Effect of protein malnutrition on rat peritoneal mast cell number, histamine content, and IgE receptors. Am. J. Clin. Nutr. 49:641-645 (1989).
6.
Lagunoff, D., Rickard, A., and Marquardt, C. Rat Mast Cell Tryptase. Arch. Biochem. Biophys. 291:52-58 (1991).
7.
Rickard, A., Lagunoff, D. Eosinophil Peroxidase Accounts for Most if not All of the Peroxidase Activity Associated with Isolated Rat Peritoneal Mast Cells. Int. Arch. Allergy Immunol. 103-104:365-369 (1994).
8.
Lagunoff, D and Rickard, A. Mast cell granule proteoglycan induces lacunae in confluent endothelial monolayers. Am. J. Path. 154: 1591-1600 (1999).
9.
Rickard, A., Portell, C. and Lagunoff, D. Effect of mast cell granules on urinary tract epithelial cells in culture. Urology 57: abstract ICBR-31 114, (2001).
10.
McHowat, J., Creer, M.H., and Rickard, A. Stimulation of protease activated receptors on RT4 cells mediates arachidonic acid release via Ca2+ independent phospholipase A2. J. Urol. 165: 2063-2067 (2001) .
11.
Rickard, A. and McHowat, J. Phospholipid metabolite production in human urothelial cells after protease-activated receptor cleavage. Am. J. Physiol. 52: F944-F951 (2002)
12.
Rickard, A., Portell, C., Siegal J., Goeckeler, Z. and Lagunoff, D. Measurement of the motility of endothelial cells in confluent monolayers. Microcirculation 10: 193-203 (2003)
13.
Rickard A, Portell C, Kell PJ, Vinson SM, McHowat J, Protease activated receptor stimulation activates a calcium-independent phospholipase A2 in bladder microvascular endothelial cells. Am J Physiol-Renal Physiology. 288:F714-721, 2005.
14.
Vinson SM, Rickard A, Ryerse JS, McHowat J. Neutrophil adherence to bladder microvascular endothelial cells following platelet-activating factor acetylhydrolase inhibition. J Pharm & Exp Therap. 314:1241-1247, 2005.
15.
Portell C, Rickard A, Vinson S, McHowat J. Prostaglandin production in tryptase and thrombin stimulated human bladder endothelial cells: effect of pretreatment with phospholipase A2 inhibitors. J Urol 176:1661-1665, 2006
16.
Rastogi P, Rickard A, Dorokhov A, Klumpp D, McHowat J. Loss of prostaglandin E2 release from immortalized urothelial cells obtained from interstitial cystitis patient bladders. Am J Physiol Renal Physiol 294: F1129-F1135, 2008
17.
Rastogi P, White MC, Rickard A, McHowat J. Potential mechanism for recruitment and migration of CD133 positive cells to areas of vascular inflammation. Thrombosis Research 123:258-266, 2008
18.
Rickard A, Dorokhov N, Ryerse J, Klumpp DJ, McHowat J. Characterization of tight junction proteins in cultured human urothelial cells. In Vitro Cellular & Developmental Biology-Animal 44:261-267, 2008
19.
Rastogi P, Rickard A, Klumpp DJ, McHowat J. Urothelial cell platelet-activating factor production is mediated via calcium-independent phospholipase A2Îł. In Press Urology