Curriculum Vitae Guilan Chen, M.D. Education: Medical Education 09 / 1985 - 07 / 1990 Zhejiang College of Traditional Chinese Medicine, China MB, 07 / 1990 Graduate Education 05 / 1993 - 07 / 1995 Kansas State University, Manhattan, Kansas Biology, MS, 12 / 1995
Postgraduate Training: 07/2010 – 06/2011 Fellow, Gastrointestinal and Liver Pathology, Saint Louis University School of Medicine, Department of Pathology 07/2006 - 06/2010 Resident, Anatomic/Clinical Pathology, Saint Louis University School of Medicine, Department of Pathology
Board Certification and Licensure: Diplomat of the American Board of Pathology, Anatomic and Clinical Pathology, 08/2010 Missouri, Physician and Surgeon, Medical License #2010005430
Current Position: 06/2011 - present Assistant professor, Anatomic Pathology, Gastrointestinal and Liver Pathology, Renal Pathology and Transplant Pathology, Saint Louis University School of Medicine, Department of Pathology, 1402 South Grand Blvd., St. Louis, MO 63104
Previous Professional Experience: 08 / 1996 - 07 / 2005 Research Scientist/Scientific Programmer, Monsanto Company
Teaching Experience: Lecturer, Pathology Course, Southern Illinois University in Edwardsville Dental School, Alton, IL, 07/2010 – 06/2011
Medical Student Pathology Laboratories, Saint Louis University School of Medicine, Saint Louis, MO, 07/2006 – 06/2010
Administrative Experience: Administrative Chief Resident, Department of Pathology, Saint Louis University School of Medicine, 07/2010 - 06/2011 Course director, PA401, Anatomic Pathology, Department of Pathology, Saint Louis University School of Medicine, Saint Louis, MO, 06/2011- present Course director, PA404, Cytopathology Clerkship, Department of Pathology, Saint Louis University School of Medicine, Saint Louis, MO, 06/2011- present
Professional Society Memberships: American Society of Plant Biologists, 2001 American Society of Clinical Pathology, 2006-present College of American Pathologists, 2006-present United States and Canadian Academy of Pathology, 2007-present The Wagih Bari Society of St. Louis Pathologists, 2006-present Renal Pathology Society, junior member, 2011-present
Honorary Societies, Honors and Awards: Top 10 finalists, AJCP Resident Research Symposium, 2009 ASCP annual meeting 2004 U.S. Patent number 6,689,880; "DNA molecule for detecting glyphosate tolerant wheat plant 33391 and progeny thereof" 2003 U.S. Patent number 6,645,765; "Plant regulatory sequences for control of gene expression"
Committee Memberships: Safety committee, Saint Louis University Hospital, Saint Louis, MO, 07/2009 – 05/2011 SLU CAP representative, 05/2010 - 05/2011
Publications: 1. Chen G, Brunt EM. Diabetic Hepatosclerosis: A 10 Year Autopsy Series. Liver Int. 2009 Aug;29(7):1044-50. 2. Hu T, Metz S, Chay C, Zhou HP, Biest N, Chen G, Cheng M, Feng X, Radionenko M, Lu F, Fry J. Agrobacterium-mediated large-scale transformation of wheat (Triticum aestivum L.) using glyphosate selection. Plant Cell Rep 2003; 21(10):1010-19.
3. Chen G, Wang L, Liu S, Chuang C, Roche TE. Activated function of the pyruvate dehydrogenase phosphatase through Ca2+-facilitated binding to the inner lipoyl domain of the dihydrolipoyl acetyltransferase. J Biol Chem 1996; 271(45):28064-70. 4. Gao XM, Perchellet EM, Davis AW, Newell SW, Chen G, Hua DH, Perchellet JP. Camptothecin post-treatments inhibit the biochemical events linked to the tumor-promoting component of carcinogenesis in mouse epidermis in vivo. Int J Cancer 1996; 66(4):496-505. 5. Newell SW, Perchellet EM, Gao XM, Chen G, Perchellet JP. Ability of okadaic acid and other protein phosphatase inhibitors to mimic the stimulatory effects of 12-O-tetradecanoylphorbol-13-acetate on hydroperoxide production in mouse epidermis in vivo. Cancer Lett 1996; 98(2):241-51. 6. Chen G, Perchellet EM, Gao XM, Johnson FK, Davis AW, Newell SW, Hemingway RW, Bottari V, Perchellet. Characterization of the tumorpromoting activity of m-chloroperoxybenzoic acid in SENCAR mouse skin and its inhibition by gallotannin, oligomeric proanthocyanidin, and their monomeric units. Int J Oncology 1996; 8:197-206. 7. Chen G, Perchellet EM, Gao XM, Newell SW, Hemingway RW, Bottari V, Perchellet JP. Ability of m-chloroperoxybenzoic acid to induce the ornithine decarboxylase marker of skin tumor promotion and inhibition of this response by gallotannins, oligmeric proanthocyanidins, and their monomeric units in mouse epidermis in vivo. Anticancer Res 1995; 15(4):1183-9. 8. Gao XM, Perchellet EM, Chen G, Newell SW, Perchellet JP. Characterization of the tumor-promoting activity of thapsigargin in CF-1 mouse skin. Int J Oncology 1994; 5:793-803.
Abstracts: 1. Guilan Chen, MD, Harvey Solomon, MD, and Kiyoko Oshima, MD. The Extrahepatic Bile Duct Lesion In End-stage Primary Sclerosing Cholangitis. Am J Clin Pathol 2009;132:621 2. G Chen, EM Brunt. Diabetic Hepatosclerosis: A 10 Year Autopsy Series. Modern Pathology 2008; 21(supplement1):301A. 3. Gretchen Johns, Guilan Chen, John Richart, Stephanie Becker-Koepke, Dana Oliver, Alan L. Lipe, Michael Creer. Characterization of Immature Reticulocytes Fraction and Absolute Neutrophil Count Following Engraftment in a Tandem Cord Blood Transplant Patient. Arch Pathol Lab Med 2007; 131:1413.
4. Perchellet JP, Gao XM, Perchellet EM, Newell SW, Chen G, Hua DH. Int J Oncology, Ability of camptothecin to inhibit the biochemical events linked to the tumor-promoting component of carcinogenesis in mouse epidermis in vivo. 1st World Congress on Advances in Oncology, Athens, Greece. Int J Oncology 1995; 7 (Suppl.):1005. 5. Perchellet JP, Gao XM, Perchellet EM, Davis AW, Newell SW, Chen G, Hua DH. Characterization of the antitumor-promoting activity of camptothecin in mouse epidermis in vivo. 1st World Congress on Advances in Oncology, Athens, Greece. Int J Oncology 1995; 7 (Suppl.):983. 6. Gao XM, Perchellet EM, Newell SW, Chen G, Hua DH, Perchellet JP. Ability of camptothecin posttreatments to inhibit the prolonged stimulations of DNA synthesis caused by tumor promoter and carcinogen in mouse epidermis in vivo. 8th Annual Kansas Health Foundation Cancer Res & Training Symposium, Lawrence, KS 1995 , Abstract 26. page:43. 7. Chen G, Perchellet EM, Gao XM, Newell SW, Hemingway RW, Bottari V, Perchellet JP. Characterization of the potent ornithine decarboxylase-inducing activity of m-chloroperoxybenzoic acid and its inhibition by hydrolyzable and condensed tannins in mouse epidermis in vivo. Proc Am Assoc Cancer Res 1995; 36:178. 8. Newell SW, Perchellet EM, Gao XM, Chen G, Perchellet JP. Comparison of the hydroperoxide-producing activities of okadaic acid and other protein phosphatase inhibitors in mouse epidermis in vivo. Proc Am Assoc Cancer Res 1995; 36:179. 9. Perchellet JP, Perchellet EM, Gao XM, Gali HU, Newell SW, Chen G, Bottari V. Characterization of the tumor-promoting activity of thapsigargin in SENCAR mouse skin and its modulation by gallotannin. Proc Am Assoc Cancer Res 1995; 36:123 10. Gao XM, Perchellet EM, Newell SW, Chen G, Hua DH, Perchellet JP. Ability of camptothecin to inhibit the biochemical markers of mouse skin tumor promotion in vivo. Proc Am Assoc Cancer Res 1995; 36:441. 11. Newell SW, Perchellet EM, Gao XM, Chen G, Perchellet JP. Characterization of the hydroperoxide response to okadaic acid and palytoxin in mouse epidermis in vivo. Proc Am Assoc Cancer Res 1994; 35:156.
Presentations (national and international meetings): AJCC Resident Research Symposium, 2009 AJCC annual meeting, 10/2009, Chicago, Illinois.