Regulation of Organic Metabolism Growth and Energy Balance 0524

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Genetic, Maternal & Uterine Factors • The height of the mother correlates better with fetal size than the height of the father. • First-born infants are on the average 100 g heavier than subsequent infants • Maternal alcohol ingestion: fetal length and mental development • Fetal alcohol syndrome: microcephaly, mental retardation, midfacial hypoplasia, short palpebral fissures, wide-bridge nose, long philtrum (人中), and narrow vermilion border of the lips • Smoking causes not only retarded intrauterine growth but also decreased postnatal growth for as long as 5 years after parturition. • Maternal infection: toxoplasmosis, rubella, cytomegalovirus infection, herpes 45


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