PAN International List of Highly Hazardous Pesticides (PAN List of HHPs) November 2013
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This ‘PAN International List of Highly Hazardous Pesticides’ has been drafted by Pesticide Action Network Germany for ‘Working Group 1: Pesticides & Corporations of Pesticide Action Network International. PAN Germany thanks the members of PAN International Working Group 1 for the constructive discussion and especially Dr. Rolf Altenburger (PAN Germany) and Dr. Meriel Watts (PAN Aotearoa/New Zealand) for their valuable contributions. The PAN List of HHPs was adopted by the PAN International Working Group November 2008 and by the PAN International Regional Coordinators January 2009. The updated PAN List of HHPs 2010 was adopted by PAN International Working Group 1 November /2010 and by the PAN International Regional Coordinators 12/2010. A formal update was done by PAN Germany November 2013.
Pestizid Aktions-Netzwerk e.V. (PAN Germany) Nernstweg 32 22765 Hamburg Germany Email: info@pan-germany.org www.pan-germany.org www.pan-international.org Hamburg/Germany: November 2013 Authors: Lars Neumeister, Carina Weber
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About this publication For decades, the distribution and use of hazardous pesticides is an issue of concern. Since its founding in 1982, Pesticide Action Network (PAN) has been the civil society organization (CSO) most steadily and continuously calling for effective international action towards the elimination of hazardous pesticides. And PAN has been one of the key driving forces among non-governmental organizations (NGOs) for improving plant protection policies towards safer, socially just and economically viable pest management systems. In 1985, the International Code of Conduct on the Distribution and Use of Pesticides was adopted by FAO to respond to the growing evidence of risks associated with the use of pesticides. Already this first version of the Code of Conduct indirectly questioned the “safe use” concept as an overall approach to solve pesticide related problems, as it says in Article 5.2.3 that industry should halt sale and recall products when handling or use pose an unacceptable risk under any use directions or restrictions. Since the 1980s a number of international instruments and guidelines have been adopted1 to tackle pesticide related problems. Additionally, many public and private initiatives have been implemented to reduce the adverse effects of pesticide use in agriculture. However, overall the initiatives have been successful only to a limited extent and the concept of a safe use of highly hazardous pesticides has been questioned increasingly by NGOs/CSOs, scientists, governmental representatives and in the private sector. Meanwhile numerous initiatives in food, forest and flower production and distribution chains resulted in black lists for specific pesticides, and in November 2009, the European Union abandoned the risk assessment paradigma with regulation 1107/2009/EC2 and decided that substances proven to be carcinogenic, mutagenic, toxic for reproduction and endocrine disruptors shall not be authorized in the EU. In November 2006 the FAO Council discussed and endorsed SAICM, the Strategic Approach to International Chemicals Safety. In view of the broad range of activities envisaged within SAICM, the Council suggested that the activities of FAO could include risk reduction, including the progressive ban on highly hazardous pesticides, promoting good agricultural practices, ensuring environmentally sound disposal of stock-piles of obsolete pesticides and capacity-building in establishing national and regional laboratories. In April 2007 the FAO Council informed COAG3 of its intention to develop a new initiative for pesticide risk reduction. COAG welcomed the initiative to reduce risks associated with the use of hazardous pesticides including the progressive ban on highly hazardous pesticides. In October 2007 the FAO/WHO Panel of Experts on Pesticide Management discussed the so-called thought starter “Addressing Highly Toxic Pesticides (HTPs)” with a note from the 1
E.g. the Rotterdam Convention on the Prior Informed Consent Procedure for Certain Hazardous Chemicals and Pesticides in International Trade (http://www.pic.int), the Stockholm Convention on Persistent Organic Pollutants (http://www.pops.int) or the Strategic Approach to International Chemicals Management (http://www.saicm.org/) 2 EC (2009): Regulation (EC) No 1107/2009 of the European Parliament and of the Council of 21 October 2009 concerning the placing of plant protection products on the market and repealing Council Directives 79/117/EEC and 91/414/EEC. Official Journal of the European Union L 309. 24.11.2009 3 The FAO Committee on Agriculture (COAG) conducts periodic reviews and appraisals of agricultural and nutritional problems in order to propose concerted action by Member Nations and the Organization. It also reviews the agriculture and food and nutrition work programs of the Organization and their implementation, with emphasis on the integration of all social, technical, economic, institutional and structural aspects in promoting agricultural and rural development. Its functions are enumerated in Rule XXXII of the General Rules of the Organization. Membership must be renewed formally each biennium
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Secretariat explaining: “Through this thought-starter FAO wishes to start its work on highly hazardous pesticides.” (...) “This thought-starter builds on the information document provided to COAG on pesticide risk reduction 4 . As a first step, this paper focuses on options for defining highly hazardous pesticides.” Based on this thought starter the Panel of Experts outlined criteria to identify highly hazardous pesticides. In addition, the Panel of Experts “recommended that FAO and WHO, as a first step, should prepare a list of HHPs based on the criteria identified, and update it periodically in cooperation with UNEP. It further requested that such a list should be made widely known to all stakeholders involved in pesticide regulation and management.”5
PAN strongly welcomed these decisions made by the FAO Council, the COAG and the FAO/WHO Panel of Experts on Pesticide Management. PAN was of the opinion however, that the list of indicators agreed by the Panel of Experts had some important shortcomings; in particular it is important to note that pesticides with endocrine disrupting properties, ecotoxicological properties, or inhalative toxicity have not been taken into account by the FAO/WHO Panel of Experts. Because of these shortcomings, PAN International decided to independently develop a definition of “Highly Hazardous Pesticides” (HHPs) with a more comprehensive set of indicators and to achieve a list of HHPs based on the PAN list of indicators. This publication describes how PAN defines Highly Hazardous Pesticides (HHPs) by identifying the indicators. An explanation of the indicators is followed by a list of HHPs on the basis of the indicators. It is important to note that also the list of HHPs presented in this publication is still not complete. There are several reasons for the limitations in completeness. A major reason is that the indicators used for the PAN definition of HHPs are based on widely accepted classifications. Due to the time needed for achieving consented classifications these classifications do have shortcomings as explained in this publication. Correspondingly, there are “emerged priorities” e.g. pesticides with endocrine disrupting properties. Such properties are not sufficiently operationalised for pesticides as yet. Measures to identify substances of high environmental concern have been restricted to the application of consented criteria indicating ubiquitous environmental occurrence and hazardous properties for one ecosystem service: bees. In addition, pesticides that may be shown to be linked with a high incidence of severe or irreversible adverse effects on human health or the environment are not identified systematically yet. PAN will identify and list such highly hazardous pesticides in the future. Experiences in the past show that pesticides being classified as “moderately hazardous” by the World Health Organization (WHO) give reason for concern even though they are
This document is available at: http://www.fao.org/unfao/bodies/coag/coag20/index_en.htm The minutes of the panel of experts meeting October 2007 are available at: http://www.fao.org/agriculture/crops/core-themes/theme/pests/code/panelcode/en/
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just classified as moderately hazardous. Examples are endosulfan and paraquat, pesticides that caused hundreds of poisonings, or pyrethrins which became known to cause various incidences in the US. However, due to prioritization PAN has not added WHO II (“moderately hazardous”) pesticides to the list of indicators. In order to implement a progressive ban of highly hazardous pesticides as supported by the FAO Council, the COAG, the FAO/WHO Panel of Experts for Pesticide Management and others, all stakeholders mentioned in the International Code of Conduct on the Distribution and Use of Pesticides should develop plans of action for a progressive ban of HHPs. These are governments, the pesticide industry, the food industry, farmers and farmer’s organizations, and public interest groups. This is especially important as there are currently no legal instruments available to achieve a structured and clearly targeted global progressive ban of HHPs other than the Stockholm convention for Persistent Organic Pollutants which focuses only on a very small group of HHPs. This PAN list of HHPs provides a basis for action to implement the progressive ban of highly hazardous pesticides. PAN would like to encourage individuals, institutions, organizations and companies to develop a plan of action with priorities, timeframes and concrete measures. PAN itself will support such initiatives wherever possible. Carina Weber / PAN Germany for PAN International Hamburg, November 2013
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What is new in the 2013 edition? Indicators based on EU Directive 65/548/EC on Classification & Labeling are replaced by the appropriate classification under the Globally Harmonized System (GHS). The HHP List is not affected by this change, because the EU classification ‘translates’ into the GHS (for details see the EU Regulation [1272/2008]). Furthermore, some substances like arsen and its compounds were grouped together (see table 1). This makes the list more compact and more consistent with the national and international regulations. Obsolete pesticides were deleted. Table 1: List of groups and compounds Group and substances (intend) Arsen and ist coumpounds Arsenic pentoxide Cacodylic acid; dimethylarsinic acid MSMA Sodium arsenate Cacolydate; sodium dimethylarsinate
DNOC and ist salts DNOC ammonium salt DNOC potassium salt DNOC sodium salt
Paraffin oils; mineral oils Paraffin oil/(CAS 64741-89-5) Paraffin oil/(CAS 64741-97-5) Paraffin oil/(CAS 64742-46-7) Paraffin oil/(CAS 64742-54-7) Paraffin oil/(CAS 64742-55-8) Paraffin oil/(CAS 64742-65-0) Paraffin oil/(CAS 72623-86-0) Paraffin oil/(CAS 97862-82-3)
Mercury and ist compounds Mercuric chloride Mercuric oxide
CAS Number 7778-39-4 1303-28-2 75-60-5 2163-80-6 13464-38-5 124-65-2
534-52-1 2980-64-5 5787-96-2 2312-76-7
64741-88-4 64741-89-5 64741-97-5 64742-46-7 64742-54-7 64742-55-8 64742-65-0 72623-86-0 97862-82-3
7439-97-6 7487-94-7 21908-53-2
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PAN International Indicators for Identifying ‘Highly Hazardous Pesticides’ The following Table shows the criteria and sources used by PAN to identify pesticides considered to be highly hazardous according to PAN. High acute toxicity ‘Extremely hazardous’ (Class Ia) according to WHO Recommended Classification of Pesticides by Hazard or ‘Highly hazardous’ (Class Ib) according to WHO Recommended Classification of Pesticides by Hazard or ‘Fatal if inhaled’ (H330) according to the Globally Harmonized System (GHS) or Long term toxic effects Carcinogenic to humans according to IARC, US EPA or ‘Known or presumed human carcinogens’ (Category I) according to the Globally Harmonized System (GHS) or Probable/likely carcinogenic to humans according to IARC, US EPA or Possible human carcinogen/ Suggestive evidence of carcinogenic potential according to IARC, US EPA or ‘Suspected human carcinogen’ (Category 2) according to the Globally Harmonized System (GHS) or ‘Substances known to induce heritable mutations or to be regarded as if they induce heritable mutations in the germ cells of humans’, ‘Substances known to induce heritable mutations in the germ cells of humans’ (Category I) according to the Globally Harmonized System (GHS) or ‘Known or Presumed human reproductive toxicant’ (Category I) according to the Globally Harmonized System (GHS) or Endocrine disruptor ‘Suspected human reproductive toxicant’ (Category 2) AND ‘Suspected human carcinogen’ (Category 2) according to the Globally Harmonized System (GHS) or potential endocrine disruptor according to EU Category 1 and Category 2 or High environmental concern Pesticides listed in Annex A & B of the Stockholm Convention or Ozone depleting according to the Montreal Protocol or ‘Very bioaccumulative’ according to REACh (BCF >5000) or ‘Very persistent’ according to REACh (half-life > 60 d in marine- or freshwater or half-life > 180 d in marine or freshwater sediment) or Hazard to ecosystem services ‘Highly toxic for bees’ according to U.S. EPA (LD50, µg/bee < 2) or Known to cause a high incidence of severe or irreversible adverse effects Pesticides listed in Annex III of the Rotterdam Convention
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Explanatory notes and comments regarding the classification systems, lists and indicators being used by PAN to identify Highly Hazardous Pesticides The Globally Harmonised System of Classification and Labeling of Chemicals (GHS) The aim of the GHS is a global harmonization of the classification and labeling of chemicals. The Plan of Implementation of the World Summit on Sustainable Development (WSSD), adopted in Johannesburg in 2002, encourages countries to implement the GHS as soon as possible with a view to having the system fully operational by 2008. However, on global scale it has not been fully implemented yet. The European Union already started to convert its classification and labeling system (Directives 67/548/EC and 1999/45/EC) to the GHS system (Regulation 1272/2008/EC). By 2015 the older Directive will be replaced, until then both systems will exist in parallel. Since the GHS classification has not been established on a global scale PAN International applies the EU GHS (Regulation 1272/2008/EC and its amendments) for the development of the List of HHPs.
The WHO Recommended Classification of Pesticides by Hazard The latest revision of the WHO Recommended Classification of Pesticides by Hazards was conducted in 2009 and contains about 870 pesticides. PAN included those pesticides listed in WHO Class Ia and Ib into the PAN HHP list. The most recent version of the WHO classification must be considered incomplete for the following reasons: - Since the last revision a large number of new active ingredients entered market, but their hazards have not been classified by WHO. - LD50 values for inhalative toxicity are not included in the WHO classification. This is a major deficiency because users of pesticides are often exposed via inhalation. - Endocrine disruption is not included in the WHO classification. - Formulations are not included in the classification. The acute toxicity of formulations and mixtures can be calculated based on the percentage and the LD50 values of the active ingredients in the formulation or mixture. However, so-called ‘inert’ ingredients or solvents6 are neglected in this calculation although they may have an influence on the toxicity of the formulation or the mixture. Source used: WHO (2010): The WHO recommended classification of pesticides by hazard and guidelines to classification 2009, International Program on Chemical Safety (IPCS) & World Health Organization (WHO), Geneva.
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“Inert” ingredient: substances which can enhance the efficiency of the active substance, make a product more degradable or easier to use. ‘Inerts’ are mostly handled as trade secrets of the manufacturer, which means they are not labeled on the product and therefore not included in the calculation. PAN International list of Highly Hazardous Pesticides - PAN Germany for PAN International - 11/2013
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Regulation 1272/2008/EC – EU GHS The new EU Regulation1272/2008/EC on classification, labeling and packaging of substances and mixtures entered into force in January 2009. It implements the Globally Harmonised System (GHS). Classification and labeling of chemicals according to EU Regulation1272/2008/EC follows very similar criteria as Council Directive 67/548/EC, but uses instead of danger symbols new pictograms and instead of Risk and Safety phrases Hazard Statements and Precautionary Statements, respectively. PAN uses EU Regulation1272/2008/EC and its amendments complimentary to Directive 67/548/EC to identify pesticides which are considered highly toxic via inhalation, carcinogenic, mutagenic and/or toxic to reproduction. Sources used: EC (2008): Regulation (EC) No 1272/2008 of the European Parliament and of the Council of 16 December 2008 on classification, labeling and packaging of substances and mixtures, amending and repealing Directives 67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006. Official Journal of the European Union L 353/1 and its amendments
REACh REACh, the ‘Registration, Evaluation, Authorization and Restriction of Chemicals’ is a European Union Regulation (EC/2006/1907 of 18 December 2006). It addresses the production and use of chemical substances, and their potential impacts on both human health and the environment. REACH applies to all chemicals imported or produced in the EU. The Technical Guidance Document7 on risk assessment defines the criteria for persistence and bioaccumulation, which are used for the PAN list of HHP. According to REACh chemicals are “very bioaccumulative” if their Bio-Concentration Factor (BCF) is larger than 5,000 and “very persistent” if their half-life in marine water or fresh water exceeds 60 days or their half-life in marine or freshwater sediment exceeds 180 days. Source used: ECB (2003): Technical Guidance Document on Risk Assessment in support of Commission Directive 93/67/EEC on Risk Assessment for new notified substances, Commission Regulation (EC) No 1488/94 on Risk Assessment for existing substances Directive 98/8/EC of the European Parliament and of the Council concerning the placing of biocidal products on the market. Part II. Institute for Health and Consumer Protection. European Chemicals Bureau (ECB)
International Agency for Research on Cancer (IARC) The International Agency for Research on Cancer (IARC) is part of the World Health Organization (WHO). The goal of IARC is to evaluate, with the assistance of international working groups of experts, critical reviews and evaluations of evidence of carcinogenicity and to publish them in monographs. This series of monographs started in 1972 and since
7
ECB (2003): Technical Guidance Document on Risk Assessment in support of Commission Directive 93/67/EEC on Risk Assessment for new notified substances, Commission Regulation (EC) No 1488/94 on Risk Assessment for existing substances Directive 98/8/EC of the European Parliament and of the Council concerning the placing of biocidal products on the market. Part II. Institute for Health and Consumer Protection. European Chemicals Bureau (ECB)
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then, almost 900 agents have been reviewed. Participants in the working groups are individual scientists who do not represent organizations, industry or governments. All pesticides which are classified as ‘carcinogenic to humans’ (Group 1), ‘probably carcinogenic to humans’ (Group 2A) or ‘possibly carcinogenic to humans’ (Group 2B) have been included in the PAN List of HHPs. Source used: IARC (2006): Agents reviews by the IARC Monographs, Volumes 1-95 (by CAS Numbers), International Agency for Research on Cancer (IARC), Lion, France. Website: http://monographs.iarc.fr/index.php
U.S. Environmental Protection Agency (U.S. EPA) The U.S. EPA Office of Pesticide Programs maintains a List of Chemicals Evaluated for Carcinogenic Potential8. This list is a product of the general risk assessment included in the process of pesticide registration. This classification can be seen as a further development of the IARC classification system, but also includes the potential exposure of humans9. Therefore, a low exposure potential can place a pesticide in a lower category even when sufficient evidence of carcinogenicity exists. U.S. EPA’s classification of carcinogenicity has changed several times over the last 20 years. The list is updated annually, but its focus is mostly on pesticides registered in the USA. Source used: US EPA (2012): Chemicals Evaluated for Carcinogenic Potential, November 2012, Science Information Management Branch, Health Effects Division, Office of Pesticide Programs U.S. Environmental Protection Agency (US EPA), Washington DC, USA
Classification for bee toxicity The US EPA also defines categories for environmental toxicity of pesticides10. US EPA defines a pesticide as highly toxic to bees if the LD 50 is lower than 2 microgram/bee (µg/bee). Pesticides highly toxic to bees are included in the PAN List of HHP.
EU categorization of endocrine disruptors The issue of endocrine disrupting pesticides gained widespread public, political and scientific attention at the beginning of the 1990s. Today there are still no confirmed lists of pesticides with endocrine disrupting properties on any official national or international level (e.g. EU, WHO). However, the EU has developed a priority list of pesticides with evidence for endocrine disrupting properties.
8
US EPA (2012): Chemicals Evaluated for Carcinogenic Potential, November 2012, Science Information Management Branch, Health Effects Division, Office of Pesticide Programs U.S. Environmental Protection Agency (US EPA), Washington DC, USA 9 Altenburger, R., Bödeker, W., Brückmann, S., Oetken, G., Weber, C. (1999): Zur Human- und Ökotoxizität von Pestiziden, die im Bananenanbau verwendet werden, Pestizid Aktions-Netzwerk e.V. (PAN Germany), Hamburg, Germany 10 US EPA (2013): Technical Overview of Ecological Risk Assessment Analysis Phase: Ecological Effects Characterization, U.S. Environmental Protection Agency, Washington, DC www.epa.gov/oppefed1/ecorisk_ders/toera_analysis_eco.htm PAN International list of Highly Hazardous Pesticides - PAN Germany for PAN International - 11/2013
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In the PAN list of HHPs all EU Category 1 pesticides (at least one study providing evidence of endocrine disruption in an intact organism) and Category 2 pesticides (in vitro evidence of endocrine disruption) are included. With Regulation 1107/2009/EC the European Union decided to exclude pesticide active ingredients from EU authorization, which have endocrine disrupting properties that may cause adverse effects in humans. By 14 December 2013, the European Commission shall present a draft of the measures concerning specific scientific criteria for the determination of endocrine disrupting properties. Pending the adoption of these criteria, substances that are or have to be classified in accordance with the provisions of Regulation (EC) No 1272/2008 as carcinogenic category 2 and toxic for reproduction category 2 shall be considered to have endocrine disrupting properties (EC 2009). PAN International used these preliminary criteria for the identification of endocrine disrupting chemicals and included pesticides which are classified in Regulation 1272/2008/EC as carcinogenic category 2 and toxic for reproduction category 2 as endocrine disruptors. Sources used: EC (2000): Towards the establishment of a priority list of substances for further evaluation of their role in endocrine disruption – preparation of a candidate list of substances as a basis for priority setting, European Commission, Delft EC (2004): Commission Staff Working Document SEC (2004) 1372 on implementation of the Community Strategy for Endocrine Disrupters – a range of substances suspected of interfering with the hormone systems of humans and wildlife (COM (1999) 706), European Commission, Brussels EC (2007): Commission staff working document on the implementation of the “Community Strategy for Endocrine Disrupters” – a range of substances suspected of interfering with the hormone systems of humans and wildlife (COM (1999) 706), (COM (2001) 262) and (SEC (2004) 1372). SEC(2007) 1635. European Commission (EC).Brussels, 30.11.2007 EC (2008): Regulation (EC) No 1272/2008 of the European Parliament and of the Council of 16 December 2008 on classification, labeling and packaging of substances and mixtures, amending and repealing Directives 67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006. Official Journal of the European Union L 353/1 and its amendments EC (2009): Regulation (EC) No 1107/2009 of the European Parliament and of the Council of 21 October 2009 concerning the placing of plant protection products on the market and repealing Council Directives 79/117/EEC and 91/414/EEC. Official Journal of the European Union, L 309. 24.11.2009
International Regulations The Stockholm Convention aims at the global elimination of Persistent Organic Pollutants (POPs), some of the most unwanted chemicals in the world. POPs are toxic, bioaccumulative, highly persistent, capable of long-range transport and pose a global threat to living beings, especially in the arctic region where they biomagnify. All pesticides formally adopted under these criteria to the Stockholm Convention are on the PAN HHP list. The Rotterdam Convention on the Prior Informed Consent (PIC) Procedure for Certain Hazardous Chemicals and Pesticides in International Trade regulates the exchange of information in international trade in certain hazardous pesticides (active ingredients and formulations). All pesticides formally adopted under the Rotterdam Convention are on the PAN list of HHP. Certain pesticide formulations are included in Annex 3 of the Rotterdam Convention. It is important to note that these active ingredients are on the PAN list even though they PAN International list of Highly Hazardous Pesticides - PAN Germany for PAN International - 11/2013
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are regulated only in specific formulations. These active ingredients are marked in the attachment. The Montreal Protocol on Substances that Deplete the Ozone Layer is an international treaty designed to protect the ozone layer by phasing out the production of a number of substances believed to be responsible for ozone depletion. Currently, there is one pesticide listed as ozone depleting chemical. This pesticide (methyl bromide) is on the PAN list of HHP. Sources used: Website of the Stockholm Convention at http://www.pops.int; Website of the Rotterdam Convention at http://www.pic.int; Website of Montreal Protocol at http://ozone.unep.org/
Ecosystem services – pollination by bees The U.S. EPA Office of Pesticide Programs after reviewing individual toxicity or ecological effect studies for a pesticide summarizes the toxicity of pesticides to certain species groups. In developing its ecological effect characterization, EPA uses a three-step scale of toxicity categories to classify pesticides based on bee toxicity data. All pesticides classified as ‘highly toxic to bees’ are listed in the PAN HHP list. Source used: FOOTPRINT (2012): The FOOTPRINT Pesticide Properties DataBase. Database collated by the University of Hertfordshire as part of the EU-funded FOOTPRINT project (FP6-SSP022704) (http://www.eu-footprint.org).
Method applied to identify highly hazardous pesticides The classification systems and lists mentioned above have been integrated in a relational pesticide database consisting of numerous tables representing the classification systems and lists. Matching fields between the tables are either CAS numbers or unique identification numbers (IDs). Data were usually imported from Excel, Access or PDF files. A table (list) of all pesticides is linked to all tables containing classification systems and lists mentioned above, and this table/list was searched for the criteria defining highly hazardous pesticides. Pesticides which are considered to be ‘obsolete’ by the WHO/IPCS were omitted from the search, if they are not targeted by any of the international conventions (Rotterdam Convention/PIC pesticides), Stockholm Convention/POP pesticides). The FOOTPRINT Pesticide Properties Database has been used to identify pesticides with the characteristics of being persistent, bioaccumulative and/or toxic to bees (LD50 <2 microgram/bee).
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Evolution of the PAN List of Highly Hazardous Pesticides This updated PAN International List of Highly Hazardous Pesticides is longer than the 1st version of the list dated January 16th, 2009, but shorter than the version from 2011. In 2010 more pesticides were classified as toxic to bees and as persistent. In 2013, numerous substances, which are not-agricultural pesticides or obsolete, were deleted.
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Pesticides added to the PAN HHP List since January 2009 2009-2011 Alanycarb Amidosulfuron Asulam, sodium salt Benfuracarb Bensulide beta-HCH; beta-BCH Bioresmethrin Blasticidin-S Borax; disodium tetraborate decahydrate Boric acid Carbosulfan Chlordimeform Chlorphropham Clopyralid Cyhalothrin Cyhalothrin, gamma Diafenthiuron Dimefuron Dimoxystrobin Dinotefuran Diquat dichloride Dithianon E-Phosphamidon EPTC Ethaboxam Ethirimol Fenchlorazole-ethyl Fenothiocarb Fenpropidin Flufenoxuron Glufosinate-ammonium Lenacil Metazachlor Metobromuron Metoxuron Metsulfuron-methyl Milbemectin Naled Napropamide Nicosulfuron Nitenpyram Nitrobenzene Oxycarboxin Penconazole Pentachlorbenzene Pirimiphos-methyl Prallethrin Profenofos Pyraclofos Pyrazophos Pyridaben Pyridiphenthion Pyrifenox Quinmerac Rotenone Silafluofen Sintofen Temephos Tralomethrin Tributyltin compounds Tridiphane Validamycin XMC
Since 2011 Penthiopyrad Penflufen Sedaxane o-phenylphenol
Group: Paraffin oils, Mineral oils Paraffin oil/(CAS 64741-89-5) Paraffin oil/(CAS 64741-97-5) Paraffin oil/(CAS 64742-46-7) Paraffin oil/(CAS 64742-54-7) Paraffin oil/(CAS 64742-55-8) Paraffin oil/(CAS 64742-65-0) Paraffin oil/(CAS 72623-86-0) Paraffin oil/(CAS 97862-82-3) Isopyrazam Amisulbrom Spinetoram Pyridalyl Penflufen Isopyrazam Ipconazole Penthiopyrad Sedaxane Fluxapyroxad Metazachlor Fuberidazole Oxadiargyl Zinc phosphide Cyflufenamid
Since June 2013 2,4,5-T (2,4,5trichlorophenoxy acetic acid) Aldrin Binapacryl Chlordimeform Chlorobenzilate Cholecalciferol; Vitamin D3 Dieldrin Dinoseb Endrin Heptachlor Mirex Toxaphene Metobromuron Chlordecone 8-hydroxyquinoline Oxadiargyl Methyl isothiocyanate
Since June 2013 Magnesium phosphide Proquinazid Aclonifen Imiprothrin Sulfoxaflor Climbazole Metaflumizone Aminocyclopyrachlor
Pesticides deleted from the PAN HHP List since January 2009 2009-2011 2,4-dichlorophenol Bacillus subtilis GBO3 Chlordimeform hydrochloride Chlorsulfuron Sulfosulfuron
Since 2011 1,2,4-triazole 2,4,6-trichlorophenol 2,6-Dichlorbenzamid Aniline Azobenzene Bis (chloroethyl) ether Chlorbenside Coconut diethanolamide Dichloro acetic acid Dimethoxane Doxorubicin Heptachlor epoxide Hydrazine Isophorone Mepronil Methylene chloride P-chloroaniline Pentachlorbenzene Picloram, diethanolamine salt piperonyl butoxid Trichlorophenol Tridiphane
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PAN International List of Highly Hazardous Pesticides - PAN Germany for PAN International - November 2013 Group 1: Acute Toxicity
Group 3: Environmental toxicity
1
24
0
7
max = 1
115
POP
50
See note below the table
40
PIC
18
Montr Prot
90
Group 4: Conventions
max = 1
20
highly toxic bees
4
very pers water sedi
47
very pers water
30
very bio acc
111
max = 1
EU EDC (1,2) or C2 & R2 GHS
73
EU GHS repro (1A ,1B)
4
EU GHS muta (1A, 1B)
11
EU GHS carc (2)
3
IARC poss carc
IARC prob carc
1
EPA prob likel carc
EU GHS carc (1A, 1B)
42
IARC carc
H330
48
EPA carc
WHO Ib
27
max = 1
WHO Ia
0
EPA poss carc
Pesticide sum of max=1 in Groups 1-4
CAS number
Group 2: Long term effects
1 2
542-75-6 93-80-1
1,3-dichloropropene 2,4,5-T, butyric acid
1
0
1
1
0
0
1
0
1
1
0
0
3 4 5 6
95-95-4 94-75-7 94-82-6 28631-35-8
1 1 1
0 0 0
1 1 1
1 1 1
0 0 0
0 0 0
1
0
1
1
0
0
7
149-30-4
2,4,5-trichlorophenol 2,4-D 2,4-DB 2,4-DP, isooctyl ester 2-Mercaptobenzothiazole
1
0
1
0
0
3-CPA Abamectin Acephate Acetochlor Acifluorfen, sodium salt Aclonifen Acrinathrin Acrolein Alachlor Alanycarb Aldicarb Allethrin; Bioallethrin
1 2 2 1
0 1 1 0
0 0 0 0
0
0
0 1 0 0 1 1 0
0 0 0 1 0 1 0
8 9 10 11 12
101-10-0 71751-41-2 30560-19-1 34256-82-1 62476-59-9
13 14 15 16 17 18 19
74070-46-5 101007-06-1 107-02-8 15972-60-8 83130-01-2 116-06-3 584-79-2
1
1 1
0 1 0 0
1 1
1
0
1
1 1 2 2 1 4 1
0 0 1 0 0 1 0
1
1
1
1
1
1 1
1 1
1
PAN International list of Highly Hazardous Pesticides - PAN Germany for PAN International - 11/2013
1 1
1 1
1 1
1 0 1 1
1
1 1 1
1 0 1 1 1 1
1
1 1
1 1
15
PAN International List of Highly Hazardous Pesticides - PAN Germany for PAN International - November 2013 Group 1: Acute Toxicity
1
24
0
7 1
max = 1
115
POP
50
See note below the table
40
PIC
1
1
0
1
0
0
0
1
0
1
0
1 1 1 1
0 0 0 0
1
0 0 0 1
1 1 1 0
0 0 0 0
1
0
1
0
0
2 1
0 0
1
1 0
0 0
1
0
1
0
0
1 1 1 1 1 2 3 2 1 1
0 0 0 0 0 1 1 1 0 0
1 0 1 1 0 0 0 0 0 0
0 1 0 0 1 1 1 1 1 1
0 0 0 0 0 0 1 0 0 0
1
0
18
Montr Prot
90
Group 4: Conventions
max = 1
20
highly toxic bees
4
very pers water sedi
47
very pers water
30
very bio acc
EU EDC (1,2) or C2 & R2 GHS
111
max = 1
EU GHS repro (1A ,1B)
73
EU GHS muta (1A, 1B)
4
EU GHS carc (2)
11
IARC poss carc
3337-71-1 2302-17-2 1912-24-9 68049-83-2 35575-96-3 2642-71-9 86-50-0 41083-11-8 131860-33-8 22781-23-3
3
Group 3: Environmental toxicity
EPA poss carc
31 32 33 34 35 36 37 38 39 40
Amitrole Anthracene oil Arsenic and ist compounds Asulam Asulam, sodium salt Atrazine Azafenidin Azamethiphos Azinphos-ethyl Azinphos-methyl Azocyclotin Azoxystrobin Bendiocarb
1
EPA prob likel carc
61-82-5 90640-80-5 7778-39-4
IARC prob carc
28 29 30
2
EU GHS carc (1A, 1B)
120923-37-7 858956-08-8 150114-71-9 348635-87-0 33089-61-1
42
IARC carc
23 24 25 26 27
48
EPA carc
96-24-2 20859-73-8
27
max = 1
21 22
alpha-BHC; alphaHCH Alpha-chlorohydrin Aluminum phosphide Amidosulfuron Aminocyclopyrachlor Aminopyralid Amisulbrom Amitraz
H330
319-84-6
WHO Ib
20
0
WHO Ia
Pesticide sum of max=1 in Groups 1-4
CAS number
Group 2: Long term effects
1
2
1
1 1
1 1
1 1
PAN International list of Highly Hazardous Pesticides - PAN Germany for PAN International - 11/2013
1 1 1
1 1
1
1
1 1
1 1
1
1 1
1 1
1
1 1 1 1 1 1
1
16
1
PAN International List of Highly Hazardous Pesticides - PAN Germany for PAN International - November 2013 Group 1: Acute Toxicity
Group 2: Long term effects
1
1
0
1
0
1
0 1 0 1 1 1
1 1
1
1 1
0
1
1
1
1
1
1 0 0
1 1
1
1 1
1
PAN International list of Highly Hazardous Pesticides - PAN Germany for PAN International - 11/2013
1
0 1 0 1 1
24
0
7
1
0 0 1 0 0
X
0
0
1
0
0 1 1
1
max = 1
1
1
POP
1 0 1 0 0
115
See note below the table
1
50
PIC
1
40
Montr Prot
1
18
Group 4: Conventions
max = 1
0 0 1
1
90
highly toxic bees
2 1 1
1 1
20
very pers water sedi
0
1
4
very pers water
Brodifacoum Bromacil Bromadiolone Bromethalin Bromoxynil
47
very bio acc
56073-10-0 314-40-9 28772-56-7 63333-35-7 1689-84-5
30
max = 1
55 56 57 58 59
EU EDC (1,2) or C2 & R2 GHS
10043-35-3 188425-85-6
111
1
2
1
EU GHS repro (1A ,1B)
2 1 1 2 2
53 54
1
73
EU GHS muta (1A, 1B)
82657-04-3 28434-01-7 2079-00-7 1303-96-4
1
4
EU GHS carc (2)
49 50 51 52
2
11
IARC poss carc
319-85-7
3
EPA poss carc
48
1
EPA prob likel carc
68359-37-5
IARC prob carc
47
EU GHS carc (1A, 1B)
0
42
IARC carc
1
48
EPA carc
0 0 0 0 0
27
max = 1
1 1 2 1 1
Benfluralin Benfuracarb Benomyl Bensulide Bentazone Benthiavalicarbisopropyl Beta-cyfluthrin; Cyfluthrin beta-HCH; betaBCH Bifenthrin Bioresmethrin Blasticidin-S Borax; disodium tetraborate decahydrate Boric acid Boscalid
H330
1861-40-1 82560-54-1 17804-35-2 741-58-2 25057-89-0 177406-68-7
WHO Ib
41 42 43 44 45 46
0
WHO Ia
Pesticide sum of max=1 in Groups 1-4
CAS number
Group 3: Environmental toxicity
1
1
1 1 0
0 0 0
1
0
0
1
0
0
1
0
0
1 0 0 1 0
0 0 0 0 0
0 1 0 0 1
1
1
17
PAN International List of Highly Hazardous Pesticides - PAN Germany for PAN International - November 2013 Group 1: Acute Toxicity
1 1
1 1
0
1
0
1
1
1
1 1 1
1
1
1
1 1
1
1 1 1
1 0 1 1
1
1
1 1 1
1
1 1
1
1
PAN International list of Highly Hazardous Pesticides - PAN Germany for PAN International - 11/2013
1
1
1
1 0 0 1 0 1 0 0 1 0 1 1
1
24
0
7 0 0 0 0 0 0 1 0 0 0 1 0
1
1
X
0 1
1
max = 1
1
1
0 1 1 0 0 0 1 1 1 1 1 0
POP
1
115
See note below the table
1
50
PIC
1
40
Montr Prot
1
18
Group 4: Conventions
max = 1
90
highly toxic bees
20
very pers water sedi
4
very pers water
47
very bio acc
1 1 1 1
30
max = 1
Chlormephos Chloroform Chlorophacinone Chloropicrin
EU EDC (1,2) or C2 & R2 GHS
24934-91-6 67-66-3 3691-35-8 76-06-2
111 1
0
3
EU GHS repro (1A ,1B)
77 78 79 80
1
73
EU GHS muta (1A, 1B)
2
2
4
EU GHS carc (2)
Chlorfenapyr Chlorfenvinphos
1
11
IARC poss carc
122453-73-0 470-90-6
1 1
3
Group 3: Environmental toxicity
EPA poss carc
75 76
1
1
EPA prob likel carc
3
1
IARC prob carc
Chlordane Chlorethoxyphos
1 1
0 0 0 0 1 1 1 0 0 0 1 1
EU GHS carc (1A, 1B)
57-74-9 54593-83-8
42
IARC carc
73 74
48
EPA carc
1 1 1 1 1 2 3 1 2 1 4 2
27
max = 1
Bromuconazole Buprofezin Butachlor Butocarboxim Butoxycarboxim Cadusafos Captafol Captan Carbaryl Carbendazim Carbofuran Carbosulfan Chinomethionat; Oxythioquinox
H330
116255-48-2 69327-76-0 23184-66-9 34681-10-2 34681-23-7 95465-99-9 2425-06-1 133-06-2 63-25-2 10605-21-7 1563-66-2 55285-14-8 2439-01-2
WHO Ib
60 61 62 63 64 65 66 67 68 69 70 71 72
0
WHO Ia
Pesticide sum of max=1 in Groups 1-4
CAS number
Group 2: Long term effects
0 1
1
1
0
1
1
0
1
1
1
0
1
1
1
0
0 0 0 0
0 0 0 0
0 1 0 0
18
PAN International List of Highly Hazardous Pesticides - PAN Germany for PAN International - November 2013 Group 1: Acute Toxicity
1 1
1 1 1 1
1
1
24
0
7
max = 1
1
1 1 1 0 0 1 1 1 0
115
POP
1
50
See note below the table
1 1 1
40
PIC
1
1
1 0 0 0 0 0 0 0 0
18
Montr Prot
90
Group 4: Conventions
max = 1
20
highly toxic bees
4
very pers water sedi
47
very pers water
30
very bio acc
EU EDC (1,2) or C2 & R2 GHS
111
max = 1
EU GHS repro (1A ,1B)
73
EU GHS muta (1A, 1B)
4
EU GHS carc (2)
11
IARC poss carc
3
Group 3: Environmental toxicity
EPA poss carc
1
EPA prob likel carc
1
IARC prob carc
2 2 1 1 1 2 1 1 1
EU GHS carc (1A, 1B)
42
IARC carc
48
EPA carc
82697-71-0 74115-24-5 1702-17-6 210880-92-5 56-72-4 5836-29-3 8001-58-9 99485-76-4 420-04-2 21725-46-2 180409-60-3 68085-85-8
27
max = 1
91 92 93 94 95 96 97 98 99 100 101 102
Chlorothalonil Chlorotoluron Chlorphropham Chlorpyrifos Chlorpyrifos-methyl Chlorthal-dimethyl Chlozolinate Cinidon-ethyl Climbazole Clodinafoppropargyl Clofencet Clofentezine Clopyralid Clothianidin Coumaphos Coumatetralyl Creosote Cumyluron Cyanamide Cyanazine Cyflufenamid Cyhalothrin
H330
1897-45-6 15545-48-9 101-21-3 2921-88-2 5598-13-0 1861-32-1 84332-86-5 142891-20-1 38083-17-9 105512-06-9
WHO Ib
81 82 83 84 85 86 87 88 89 90
0
WHO Ia
Pesticide sum of max=1 in Groups 1-4
CAS number
Group 2: Long term effects
0 1 0 1 1 1 0 0 1
0 0 0 0 0 0 0 0 0
1
0
1
1
0
0
1 1 1 1 1 1 1 1 1 1 1 1
0 0 0 0 1 1 0 0 0 0 0 0
1 1
1 1 0 0 0 0 1 1 1 1 1 0
0 0 1 1 0 0 0 0 0 0 0 1
0 0 0 0 0 0 0 0 0 0 0 0
1 1
1
1
1 1 1 1 1
PAN International list of Highly Hazardous Pesticides - PAN Germany for PAN International - 11/2013
1
1 1
1
19
PAN International List of Highly Hazardous Pesticides - PAN Germany for PAN International - November 2013 Group 1: Acute Toxicity
Group 2: Long term effects
1 1 1
1 1
1
1
1 1
1 1
1
1 1 1
1 1 1 1
PAN International list of Highly Hazardous Pesticides - PAN Germany for PAN International - 11/2013
1
1 0 1 1 1 0 0 1 1 1 1 1 1 1 1 0 1
1
1 1
1 1 1 1
1 1 1 1 1
1
24
0
7
max = 1
1 1
0 1
115
POP
50
See note below the table
40
PIC
0 0 0 0
18
Montr Prot
90
Group 4: Conventions
max = 1
20
highly toxic bees
4
very pers water sedi
47
very pers water
30
very bio acc
111
max = 1
EU EDC (1,2) or C2 & R2 GHS
1
EU GHS repro (1A ,1B)
1
1
73
EU GHS muta (1A, 1B)
1
4
EU GHS carc (2)
1
11
IARC poss carc
0 0 0 0 0 1 0 0 0 0 0 1 0 0 1 1 0
3
EPA poss carc
2 1 1 2 2 2 1 2 1 1 1 3 1 2 3 2 2
1
EPA prob likel carc
Cyproconazole Cyromazine Daminozide DDT Deltamethrin Demeton-S-methyl Diafenthiuron Diazinon Dichlobenil Dichlorophene Dichlorprop-P Dichlorvos; DDVP Diclofop-methyl Dicofol Dicrotophos Difenacoum Difenoconazole
IARC prob carc
0
94361-06-5 66215-27-8 1596-84-5 50-29-3 52918-63-5 919-86-8 80060-09-9 333-41-5 1194-65-6 97-23-4 15165-67-0 62-73-7 51338-27-3 115-32-2 141-66-2 56073-07-5 119446-68-3
EU GHS carc (1A, 1B)
1
108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124
42
IARC carc
0 0 0 0
48
EPA carc
1 1 1 1
27
max = 1
Cyhalothrin, gamma Cyhexatin Cypermethrin Cypermethrin, alpha Cypermethrin, beta
H330
76703-62-3 13121-70-5 65731-84-2 67375-30-8 65731-84-2
0
WHO Ib
103 104 105 106 107
WHO Ia
Pesticide sum of max=1 in Groups 1-4
CAS number
Group 3: Environmental toxicity
1 1 1 1
0 0 0 0
1
0
1 1 0 0 1 1 1 1 0 0 0 1 0 1 1 1 1
0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0
1
1
20
PAN International List of Highly Hazardous Pesticides - PAN Germany for PAN International - November 2013 Group 1: Acute Toxicity
1
1 1
1
1
1 1
1
1
1
1
1 1
PAN International list of Highly Hazardous Pesticides - PAN Germany for PAN International - 11/2013
1
1
1 1 1 1
1
1 1
1 1 0 1 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0
1
24
0
7
1 1
1
21
max = 1
1
115
POP
1
50
See note below the table
1 1
40
PIC
1 1 1
0 0 1 1 1 1 1 0 1 0 0 0 0 1 1 0 0 1 0 1 0 1 1
18
Montr Prot
90
Group 4: Conventions
max = 1
20
highly toxic bees
4
very pers water sedi
47
very pers water
30
very bio acc
111
max = 1
1
EU EDC (1,2) or C2 & R2 GHS
1 1
EU GHS repro (1A ,1B)
1
73
EU GHS muta (1A, 1B)
1 1
4
EU GHS carc (2)
1
11
IARC poss carc
1 1
3
Group 3: Environmental toxicity
EPA poss carc
1
1
EPA prob likel carc
1
1 0 0 0 0 0 0 0 1 1 1 1 1 0 0 1 1 1 1 0 1 0 0
IARC prob carc
1
EU GHS carc (1A, 1B)
42
IARC carc
48
EPA carc
27
max = 1
2 1 1 2 2 1 1 1 2 1 1 1 1 1 1 2 1 3 1 1 2 2 1
H330
Difethialone Dimefuron Dimethenamid Dimethipin Dimethoate Dimoxystrobin Dinocap Dinotefuran Dinoterb Diphacinone Diquat dibromide Diquat dichloride Disulfoton Dithianon Diuron DNOC Edifenphos Endosulfan E-Phosphamidon Epichlorohydrin EPN Epoxiconazole Esbiothrin; S-
WHO Ib
104653-34-1 34205-21-5 87674-68-8 55290-64-7 60-51-5 149961-52-4 39300-45-3 165252-70-0 1420-07-1 82-66-6 85-00-7 4032-26-2 298-04-4 3347-22-6 330-54-1 534-52-1 17109-49-8 115-29-7 297-99-4 106-89-8 2104-64-5 133855-98-8 28434-00-6
0 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147
WHO Ia
Pesticide sum of max=1 in Groups 1-4
CAS number
Group 2: Long term effects
0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 0 0 0
PAN International List of Highly Hazardous Pesticides - PAN Germany for PAN International - November 2013 Group 1: Acute Toxicity
1 1
2
0
1 1
1
1
1 1 0 0 1
PAN International list of Highly Hazardous Pesticides - PAN Germany for PAN International - 11/2013
24
0
7
1 0 0 0 0 0 1 1
0 0 0 0 0 0 0 0
1
0
0
1
0
1
1
1
0
1
1
1 1
0 0
1
1 0
1
1
1
max = 1
1
POP
0 0
1
See note below the table
2 1
1
115
PIC
1
1
50
Montr Prot
1
40
Group 4: Conventions
max = 1
1 1
1
18
highly toxic bees
0
0
0 1 1 0 1 1 0 0
very pers water sedi
90
very pers water
20
very bio acc
4
max = 1
EU EDC (1,2) or C2 & R2 GHS
2
1
47
1
1 1
1
30
1 1
0
1 1
111
1 1
2
1 2 1 1
EU GHS repro (1A ,1B)
1
EU GHS muta (1A, 1B)
73
EU GHS carc (2)
4
IARC poss carc
11
EPA poss carc
52-85-7 22224-92-6 60168-88-9 120928-09-8 114369-43-6
3
0 0 0 1 0 0 0 0
1
1
1
EPA prob likel carc
162 163 164 165 166
2
IARC prob carc
75-21-8 96-45-7 80844-07-1
1 1 1 1 1 1 1 1
EU GHS carc (1A, 1B)
159 160 161
42
IARC carc
107-06-2
48
EPA carc
158
27
max = 1
106-93-4
H330
157
WHO Ib
66230-04-4 162650-77-3 55283-68-6 29973-13-5 64529-56-2 181587-01-9 23947-60-6 26225-79-6 13194-48-4
Bioallethrin Esfenvalerate Ethaboxam Ethalfluralin Ethiofencarb Ethiozin Ethiprole Ethirimol Ethofumesate Ethoprophos; Ethoprop Ethylene dibromide; 1,2-dibromoethane Ethylene dichloride; 1,2-Dichloroethane Ethylene oxide Ethylene thiourea Etofenprox; Ethofenprox Famphur Fenamiphos Fenarimol Fenazaquin Fenbuconazole
WHO Ia
0 148 149 150 151 152 153 154 155 156
Group 3: Environmental toxicity
Pesticide sum of max=1 in Groups 1-4
CAS number
Group 2: Long term effects
0 0 1 0 1
1 1
1 1 1
1
0
0 1 0 1
0 0 0 0
0
0
22
PAN International List of Highly Hazardous Pesticides - PAN Germany for PAN International - November 2013 Group 1: Acute Toxicity
Flocoumafen
179 180 181
158062-67-0 69806-50-4 79622-59-6
Flonicamid Fluazifop-butyl Fluazinam
1 1
0 0
1
1
0
1
182
70124-77-5
Flucythrinate
2
183
131341-86-1
Fludioxonil
184
101463-69-8
Flufenoxuron
1
2
1
1
2
0
2
0
1
1
1
1
1 1
1 1
1
0 1 1 1 0 1 0
1
24
0
7
0 0 1 1 1 0 1
0 0 0 0 0 0 0
1
1
1
0
0
1
1
1
0
0
1
1
1
1
0
1
1
1
0
0
0
0
1 1
0 0
0 0
1
0
0
1
0
1
0
1
0
1
1 1
1
0
1
0
0
1
0
0
PAN International list of Highly Hazardous Pesticides - PAN Germany for PAN International - 11/2013
1 1 1
1
max = 1
90035-08-8
1
1
115
POP
178
2
1
1 0 0 0 1 0 0
50
See note below the table
51630-58-1 120068-37-3
1
40
PIC
176 177
1 1 2 2 2 1 1
18
Montr Prot
90
Group 4: Conventions
max = 1
20
highly toxic bees
4
very pers water sedi
47
very pers water
30
very bio acc
EU EDC (1,2) or C2 & R2 GHS
111
Fenbutatin-oxide Fenchlorazole-ethyl Fenitrothion Fenoxycarb Fenpropathrin Fenpropidin Fenthion Fentin acetate; Triphenyltin acetate Fentin hydroxide; Triphenyltin hydroxide Fenvalerate Fipronil
max = 1
EU GHS repro (1A ,1B)
73
EU GHS muta (1A, 1B)
4
EU GHS carc (2)
11
IARC poss carc
3
Group 3: Environmental toxicity
EPA poss carc
IARC prob carc
1
EPA prob likel carc
EU GHS carc (1A, 1B)
42
IARC carc
48
EPA carc
76-87-9
27
max = 1
175
H330
13356-08-6 103112-35-2 122-14-5 72490-01-8 39515-41-8 67306-00-7 55-38-9 900-95-8
0
WHO Ib
167 168 169 170 171 172 173 174
WHO Ia
Pesticide sum of max=1 in Groups 1-4
CAS number
Group 2: Long term effects
1 1 1
23
PAN International List of Highly Hazardous Pesticides - PAN Germany for PAN International - November 2013 Group 1: Acute Toxicity
Group 2: Long term effects
Group 3: Environmental toxicity
2
190
85509-19-9
Flusilazole
2
0
191
117337-19-6
Fluthiacet-methyl
1
0
192
66332-96-5
Flutolanil
1
0
0
193
907204-31-3
Fluxapyroxad
1
0
0
194
133-07-3
Folpet
1
0
195
68157-60-8
Forchlorfenuron
1
0
196
50-00-0
Formaldehyde
1
0
197
22259-30-9
Formetanate
2
198
98886-44-3
Fosthiazate
1
199
3878-19-1
Fuberidazole
1
200
65907-30-4
Furathiocarb
1
201
98-01-1
Furfural
1
0
202
121776-33-8
Furilazole
1
0
203
77182-82-2
1
0
204
81591-81-3
Glufosinateammonium Glyphosate trimesium
1
0
1
0
1
1
0
0
1
1
1
0
1
1
0
1
1 1
1
0 1
1 1 1
1
max = 1
1
1
1
0
0
0
1
1
0
1
1
0
1
1
0
0
1
1
0
0
1
1
0
0
1
0
1
1
0
0
0
1
1
0
1
0
0
0
0
0
1
0
0
1
0
0
1
0
0
1
0
1
0 1
0 1
max = 1
1
1
7
1
115
0 1
0
50
1
1
24
40
highly toxic bees
1
1
1
18
max = 1
1
1 1
POP
Fluoroacetamide
90
See note below the table
640-19-7
20
PIC
189
4
Montr Prot
0
47
very pers water sedi
2
30
very pers water
Fluopyram
111
very bio acc
658066-35-4
EU EDC (1,2) or C2 & R2 GHS
188
EU GHS repro (1A ,1B)
0
73
EU GHS muta (1A, 1B)
1
4
EU GHS carc (2)
Fluopicolide
11
IARC poss carc
239110-15-7
3
EPA poss carc
187
1
EPA prob likel carc
0
IARC prob carc
2
EU GHS carc (1A, 1B)
Fluometuron
42
IARC carc
0
2164-17-2
48
EPA carc
1
186
27
max = 1
Flumioxazin
H330
103361-09-7
0
WHO Ib
185
WHO Ia
Pesticide sum of max=1 in Groups 1-4
CAS number
Group 4: Conventions
1 1 1
PAN International list of Highly Hazardous Pesticides - PAN Germany for PAN International - 11/2013
1
0
1
24
PAN International List of Highly Hazardous Pesticides - PAN Germany for PAN International - November 2013 Group 1: Acute Toxicity
Hexachlorobenzene Hexachloroethane
4 1
0
1
209
79983-71-4
Hexaconazole
2
0
1
210 211
86479-06-3 608-73-1
1
0
2
0
1
212 213 214 215
78587-05-0 67485-29-4 35554-44-0 81335-37-7
Hexaflumuron Hexachlorocyclohex ane Hexythiazox Hydramethylnon Imazalil Imazaquin
1 2 1
0 0 0
1
1
0
0
216 217 218 219 220 221 222
81335-77-5 138261-41-3 72963-72-5 173584-44-6 74-88-4 1689-83-4 125225-28-7
Imazethapyr Imidacloprid Imiprothrin Indoxacarb Iodomethane Ioxynil Ipconazole
1 1 1 1 1 1 1
0 0 0 0 0 0 0
0 0 0 0 1 1 0
1
1
1 1
1
0 1
1
1
1
1
1
1
1
1
1
0 1
1
1 1 1
1 1
1
PAN International list of Highly Hazardous Pesticides - PAN Germany for PAN International - 11/2013
1
1 1
1
1 1 1 1 1
1
0
7 0
1
0 1
1
1
0
0
1
0
1
0
0 1
24
0
1
1
1
max = 1
118-74-1 67-72-1
1
115
POP
207 208
2
50
See note below the table
23560-59-0
1
0
40
PIC
206
1
18
Montr Prot
90
Group 4: Conventions
max = 1
20
highly toxic bees
4
very pers water sedi
47
very pers water
30
Haloxyfop-methyl (unstated stereochemistry) Heptenophos
very bio acc
EU EDC (1,2) or C2 & R2 GHS
111
max = 1
EU GHS repro (1A ,1B)
73
EU GHS muta (1A, 1B)
4
EU GHS carc (2)
11
IARC poss carc
3
Group 3: Environmental toxicity
EPA poss carc
IARC prob carc
1
EPA prob likel carc
EU GHS carc (1A, 1B)
42
IARC carc
48
EPA carc
H330
27
max = 1
WHO Ib
69806-40-2
0 205
WHO Ia
Pesticide sum of max=1 in Groups 1-4
CAS number
Group 2: Long term effects
1
1
0 1 0
0 0 0
1
0
1 1 1 1 0 0 1
0 0 0 0 0 0 0
25
PAN International List of Highly Hazardous Pesticides - PAN Germany for PAN International - November 2013 Group 1: Acute Toxicity
Group 2: Long term effects
Group 3: Environmental toxicity
1 1 1
1 1
1
2
0
1 1 1 1 1
0 0 0 0 0
1 1
1 1 1
PAN International list of Highly Hazardous Pesticides - PAN Germany for PAN International - 11/2013
1 1 1
1
1
1
1
0 1
1
1
1
1
1 1
1 1 1 1 1
0
7 0 0 0 0 0 0 0 0 0
1
1
0
1
1 1
1
1
1
1
24
0 1 0 1 0 0 1 0 0
1
1
1
max = 1
Mancozeb Maneb MCPA MCPB MCPP
1 1
1 1 1 1 1 1 0 1 1
115
POP
8018-01-7 12427-38-2 94-74-6 94-81-5 7085-19-0
1
50
See note below the table
121-75-5
239 240 241 242 243
1
40
PIC
238
1 1
18
Montr Prot
0
1
90
max = 1
1
1
20
highly toxic bees
0
4
very pers water sedi
0
47
very pers water
1
Magnesium phosphide Malathion
30
very bio acc
Lufenuron
12057-74-8
111
max = 1
103055-07-8
237
EU EDC (1,2) or C2 & R2 GHS
236
EU GHS repro (1A ,1B)
1
73
EU GHS muta (1A, 1B)
0
4
EU GHS carc (2)
1
11
IARC poss carc
1
3
EPA poss carc
0 0
1
1
EPA prob likel carc
1 3
1
IARC prob carc
Lenacil Lindane Linuron
0 0 0 0 0 0 1 0 0
EU GHS carc (1A, 1B)
2164-08-1 58-89-9 330-55-2
42
IARC carc
233 234 235
3
48
EPA carc
1 2 1 2 1 1 2 1 1
27
max = 1
Iprodione Iprovalicarb Isoproturon Isopyrazam Isoxaben Isoxaflutole Isoxathion Kresoxim-methyl Lactofen Lambda-cyhalothrin
H330
36734-19-7 140923-17-7 34123-59-6 881685-58-1 82558-50-7 141112-29-0 18854-01-8 143390-89-0 77501-63-4 91465-08-6
0
WHO Ib
223 224 225 226 227 228 229 230 231 232
WHO Ia
Pesticide sum of max=1 in Groups 1-4
CAS number
Group 4: Conventions
1
1
1
1
0 1
0
0
1
0
0
0
1
0
0 0 0 0 0
0 0 0 0 0
26
PAN International List of Highly Hazardous Pesticides - PAN Germany for PAN International - November 2013 Group 1: Acute Toxicity
1 0 0 0 0 0 0 0 0 1 1 1 1 0 0 0 0 0 0
1 1 1 1
1 1
1 1 1 1 1
1 1 1
PAN International list of Highly Hazardous Pesticides - PAN Germany for PAN International - 11/2013
0 1 1
0 0 0
0
0
1 0 1 1 1 1 0 0 0 1 0 1 1 1 1 1 0 1
1
1
1 1
1 1
1 1
1
1 1 1 1 1
0 1 0 0 0 1 1 1 1 1 1 1 0 0 0 1 1 0
1
24
0
7
max = 1
1
115
POP
1
50
See note below the table
1
40
PIC
1
18
Montr Prot
90
Group 4: Conventions
max = 1
20
highly toxic bees
4
very pers water sedi
47
very pers water
30
very bio acc
EU EDC (1,2) or C2 & R2 GHS
111
max = 1
EU GHS repro (1A ,1B)
73
EU GHS muta (1A, 1B)
4
EU GHS carc (2)
1
11
IARC poss carc
1 1 1 1
3
Group 3: Environmental toxicity
EPA poss carc
1 1 1 1 1 2 1 1 3 3 2 3 1 2 1 2 1 1
1
1
EPA prob likel carc
2
1 0 0
IARC prob carc
1
EU GHS carc (1A, 1B)
42
IARC carc
48
EPA carc
108-39-4 139968-49-3 108-62-3 137-41-7 137-42-8 67129-08-2 125116-23-6 18691-97-9 10265-92-6 950-37-8 2032-65-7 16752-77-5 72-43-5 74-83-9 9006-42-2 51218-45-2 19937-59-8 220899-03-6
1 1 1
27
max = 1
248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265
Mecarbam Mecoprop-P Mepanipyrim Mercury and its compounds Meta-cresol Metaflumizone Metaldehyde Metam-potassium Metam-sodium Metazachlor Metconazole Methabenzthiazuron Methamidophos Methidathion Methiocarb Methomyl Methoxychlor Methyl bromide Metiram Metolachlor Metoxuron Metrafenone
H330
2595-54-2 16484-77-8 110235-47-7 7439-97-6
0
WHO Ib
244 245 246 247
WHO Ia
Pesticide sum of max=1 in Groups 1-4
CAS number
Group 2: Long term effects
0 0 0 1
1
1 0 0 0 0 0 0 0 0 1 0 0 0 0 1 0 0 0 0
X
1
27
PAN International List of Highly Hazardous Pesticides - PAN Germany for PAN International - November 2013 Group 1: Acute Toxicity
1
1
1
1 1
1
1
1
1 1 1 1 1 1
PAN International list of Highly Hazardous Pesticides - PAN Germany for PAN International - 11/2013
1 1 1
1 1 1 1 1 1
1
0 0 1 1 0 1 0 0 1 1 1 1 1 0 1 0 0 0 1 0 0 0 0
1
24
0
7
1
max = 1
1
115
POP
1
50
See note below the table
1
1 1 0 1 1 0 1 1 0 0 0 0 0 0 0 1 1 1 1 1 1 1 1
40
PIC
1 1
18
Montr Prot
90
Group 4: Conventions
max = 1
20
highly toxic bees
4
very pers water sedi
47
very pers water
30
very bio acc
EU EDC (1,2) or C2 & R2 GHS
111
max = 1
EU GHS repro (1A ,1B)
73
EU GHS muta (1A, 1B)
4
EU GHS carc (2)
11
IARC poss carc
1
3
Group 3: Environmental toxicity
EPA poss carc
1
1
1
EPA prob likel carc
1
IARC prob carc
1
0 0 0 1 0 0 0 0 1 0 0 0 0 1 0 0 0 0 1 0 0 0 0
EU GHS carc (1A, 1B)
42
IARC carc
48
EPA carc
27
max = 1
1 1 1 3 1 1 1 1 3 1 1 1 1 1 1 1 1 1 3 1 1 1 1
H330
Metribuzin Metronidazole Metsulfuron-methyl Mevinphos MGK 326 Milbemectin Molinate MON 4660 Monocrotophos Myclobutanil Naled Napropamide Nicosulfuron Nicotine Nitenpyram Nitrapyrin Nitrobenzene Norflurazon Omethoate o-phenylphenol Orthosulfamuron Oryzalin Oxadiazon
WHO Ib
21087-64-9 443-48-1 74223-64-6 7786-34-7 136-45-8 51596-10-2 2212-67-1 71526-07-3 6923-22-4 88671-89-0 300-76-5 15299-99-7 111991-09-4 54-11-5 150824-47-8 1929-82-4 98-95-3 27314-13-2 1113-02-6 90-43-7 213464-77-8 19044-88-3 19666-30-9
0 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288
WHO Ia
Pesticide sum of max=1 in Groups 1-4
CAS number
Group 2: Long term effects
0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0
X
28
PAN International List of Highly Hazardous Pesticides - PAN Germany for PAN International - November 2013 Group 1: Acute Toxicity
0
1
0
0
0 1 0 0 1 1 1
0 0 1 1 0 0 0
0 0
1 1
1 1
1
0
1
1
0 1
1
1 0
1
1
PAN International list of Highly Hazardous Pesticides - PAN Germany for PAN International - 11/2013
1
7
0
2 2
1
0
1
1
1
1 1 1
24
0 0 0 0 0 0
1
1
1
max = 1
1
POP
1
See note below the table
1
PIC
1
115 0 1 1 1 0 1
0
1 1
50
1 0 0 0 1 0
1 1
1
40
Montr Prot
1
18
Group 4: Conventions
max = 1
90
highly toxic bees
20
very pers water sedi
4
very pers water
47
very bio acc
30
max = 1
EU EDC (1,2) or C2 & R2 GHS
2 2
111
0 1 1 1 0 1 1
1 1
1 1 1 1 0 0 0
EU GHS repro (1A ,1B)
Phenthoate Phorate
0
EU GHS muta (1A, 1B)
2597-03-7 298-02-2
1
73
EU GHS carc (2)
308 309
4
IARC poss carc
Penthiopyrad Permethrin Phenothrin
0
1
11
0 1 0 1 0 0
1
1 3 3 3 1 2 2
3
Group 3: Environmental toxicity
EPA poss carc
183675-82-3 52645-53-1 26002-80-2
1
1
EPA prob likel carc
305 306 307
1
IARC prob carc
1
1
EU GHS carc (1A, 1B)
1910-42-5 56-38-2 298-00-0 87-86-5 66246-88-6 40487-42-1 494793-67-8 219714-96-2
42
IARC carc
297 298 299 300 301 302 303 304
48
EPA carc
64741-88-4
27
max = 1
1 2 1 2 1 1
296
Oxadixyl Oxamyl Oxycarboxin Oxydemeton-methyl Oxyfluorfen Paclobutrazol Paradichlorobenzene Paraffin oils; mineral oils Paraquat dichloride Parathion Parathion-methyl PCP Penconazole Pendimethalin Penflufen Penoxsulam
H330
77732-09-3 23135-22-0 5259-88-1 301-12-2 42874-03-3 76738-62-0 106-46-7
0
WHO Ib
289 290 291 292 293 294 295
WHO Ia
Pesticide sum of max=1 in Groups 1-4
CAS number
Group 2: Long term effects
1 1
1 1
1
1
1
1 1 1 1 1 1 1
1 1
0
0
1 1
0 0
0
0
1 1
0 0
29
PAN International List of Highly Hazardous Pesticides - PAN Germany for PAN International - November 2013 Group 1: Acute Toxicity
Group 2: Long term effects
Group 3: Environmental toxicity
1 1
1 1
1 1 1
1 1 1
1 1
PAN International list of Highly Hazardous Pesticides - PAN Germany for PAN International - 11/2013
0
7
max = 1
1
24
1 1 0 1 1
1
1
0
0
0
0
0
1 1
0 0
1
0
0
1 0 1 1 1 1 1 1 0 1 1
0 1 0 0 0 0 1 1 0 1 1
0 0 0 0 0 0 0 0 0 0 0
1
1 1
1
1
1
1 1
1 1 0 1 1 0
1
115
POP
1 1
50
See note below the table
1
40
PIC
1 1
18
Montr Prot
90
max = 1
20
highly toxic bees
4
very pers water sedi
1
47
very pers water
0 0 0 0 0 0 0 0 1 0 0
30
very bio acc
1 1 1 1 1 1 2 2 1 2 2
111
max = 1
1
Prodiamine Profenofos Profoxydim Prometryn Propachlor Propanil Propargite Propazine Propetamphos Propiconazole Propoxur
EU EDC (1,2) or C2 & R2 GHS
0
29091-21-2 41198-08-7 139001-49-3 7287-19-6 1918-16-7 709-98-8 2312-35-8 139-40-2 31218-83-4 60207-90-1 114-26-1
1
EU GHS repro (1A ,1B)
1
321 322 323 324 325 326 327 328 329 330 331
1
73
EU GHS muta (1A, 1B)
1
0 1
0
4
EU GHS carc (2)
0 0
1
11
IARC poss carc
1 2
0
3
EPA poss carc
0
Prallethrin Prochloraz Procymidone
1
1
EPA prob likel carc
1
23031-36-9 67747-09-5 32809-16-8
1
0 1 1 0 0
IARC prob carc
299-45-6
318 319 320
1
EU GHS carc (1A, 1B)
317
Polyhexamethylene biguanidine Potasan
42
IARC carc
32289-58-0
48
EPA carc
316
2 4 1 2 2
27
max = 1
Phosmet Phosphamidon Phosphine Picloram Pirimicarb Pirimiphos-methyl
H330
732-11-6 13171-21-6 7803-51-2 1918-02-1 23103-98-2 29232-93-7
0
WHO Ib
310 311 312 313 314 315
WHO Ia
Pesticide sum of max=1 in Groups 1-4
CAS number
Group 4: Conventions
1 1
1
1
1 1 1 1
0 1 0 0 0
1
30
PAN International List of Highly Hazardous Pesticides - PAN Germany for PAN International - November 2013 Group 1: Acute Toxicity
Group 2: Long term effects
7
max = 1
0
0
0
1
0
0
1
1
0
0
1
0
0 1 0 1 1 0 0 1 1 1 1 0 0 0 1 1 1 1
0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
1 1
1
1 1 1
PAN International list of Highly Hazardous Pesticides - PAN Germany for PAN International - 11/2013
24
1
1
1
1
1
1
0 1
115
POP
1
50
See note below the table
1
1
40
PIC
1
18
Montr Prot
90
Group 4: Conventions
max = 1
1
20
highly toxic bees
0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0
4
very pers water sedi
1 1 1 2 1 1 1 1 1 1 1 1 1 1 2 1 1 1
47
very pers water
Pymetrozine Pyraclofos Pyraflufen-ethyl Pyrasulfotole Pyrazophos Pyrazoxon Pyrethrins Pyridaben Pyridalyl Pyridiphenthion Pyrifenox Pyrimethanil Pyrithiobac-sodium Pyroxasulfone Quinalphos Quinmerac Quinoclamine Quinoxyfen
30
very bio acc
123312-89-0 77458-01-6 129630-19-9 365400-11-9 13457-18-6 108-34-9 121-21-1 96489-71-3 179101-81-6 119-12-0 88283-41-4 53112-28-0 123343-16-8 447399-55-5 13593-03-8 90717-03-6 2797-51-5 124495-18-7
111
max = 1
336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353
EU EDC (1,2) or C2 & R2 GHS
0
EU GHS repro (1A ,1B)
1
1
73
EU GHS muta (1A, 1B)
Prosulfocarb
4
EU GHS carc (2)
0
52888-80-9
11
IARC poss carc
1
335
3
EPA poss carc
Proquinazid
1
EPA prob likel carc
189278-12-4
IARC prob carc
334
EU GHS carc (1A, 1B)
0
42
IARC carc
0
1
48
EPA carc
1
27
max = 1
Propylene oxide Propyzamide
H330
75-56-9 23950-58-5
0
WHO Ib
332 333
WHO Ia
Pesticide sum of max=1 in Groups 1-4
CAS number
Group 3: Environmental toxicity
1
1 0 1 1 0 0 1 0 0 0 0 1 1 1 1 0 0 0
1 1
1 1
1 1 1 1
1 1 1 1
31
PAN International List of Highly Hazardous Pesticides - PAN Germany for PAN International - November 2013 Group 1: Acute Toxicity
Group 2: Long term effects
1 1
24
0
7
0
0
0
0
1 1
1 1 1
0 0 0
1
1
0
1 0 1 0
0 0 0 0
1
0
0
1
0
0
0
1 1
0 0
0 0
1 1
0 0
1
0
1
0
0
0 0 0 1 1
0 0 1 0 1
0 0 0 0 0
1
1
1
1 1 1
1 1 0 1 0
1
1
1
max = 1
1 1 1 2 2
115
POP
Strychnine Sulfotep Sulfoxaflor TCMTB Tebuconazole
50
See note below the table
57-24-9 3689-24-5 946578-00-3 21564-17-0 107534-96-3
40
PIC
369 370 371 372 373
1
18
Montr Prot
187166-15-0 168316-95-8 148477-71-8
90
Group 4: Conventions
max = 1
366 367 368
20
highly toxic bees
62-74-8
4
very pers water sedi
0
47
very pers water
1
30
very bio acc
1 1 1 1
0 0 0 0
365
Silthiofam Simazine Sintofen S-Metolachlor Sodium dimethyl dithio carbamate Sodium fluoroacetate (1080) Spinetoram Spinosad Spirodiclofen
111
max = 1
175217-20-6 122-34-9 130561-48-7 87392-12-9 128-04-1
EU EDC (1,2) or C2 & R2 GHS
360 361 362 363 364
EU GHS repro (1A ,1B)
0
73
EU GHS muta (1A, 1B)
2
4
EU GHS carc (2)
0 0 0
11
IARC poss carc
2 1 2
3
EPA poss carc
Resmethrin Rotenone Sedaxane Silafluofen
1
EPA prob likel carc
0
10453-86-8 83-79-4 874967-67-6 105024-66-6
IARC prob carc
1
356 357 358 359
EU GHS carc (1A, 1B)
Quizalofop-p-tefuryl
42
IARC carc
0
119738-06-6
48
EPA carc
1
355
27
max = 1
Quintozene
H330
82-68-8
0
WHO Ib
354
WHO Ia
Pesticide sum of max=1 in Groups 1-4
CAS number
Group 3: Environmental toxicity
1
1 1 1 1 1
1
1 1
PAN International list of Highly Hazardous Pesticides - PAN Germany for PAN International - 11/2013
1 0 1
1
1 1
0 1 0 1
1 1
1
1 1
1 1
32
PAN International List of Highly Hazardous Pesticides - PAN Germany for PAN International - November 2013 Group 1: Acute Toxicity
Group 2: Long term effects
1
2 2 2 1 1 1 1 2 2 2 1 1
0 0 0 0 0 0 0 0 1 1 0 0
1 1
1 1
0
0
0
1
0
0
0
1 1 0 0
0 0 0 0
0
0
1 1 1 0 0 1 0 1 1 1 0 0
0 0 0 0 0 0 0 0 0 0 0 0
1
1
0 1 0 1
1
1
1
1 1 1 1 1 0 1 1 0 0 1 1
1 1 1 1 1
1
PAN International list of Highly Hazardous Pesticides - PAN Germany for PAN International - 11/2013
1
7
0
1
1
0
max = 1
0
POP
1
24
0 1
0
1
1
1
1 1
115
See note below the table
1
1
50
PIC
1
40
Montr Prot
1
18
Group 4: Conventions
max = 1
90
highly toxic bees
20
very pers water sedi
4
very pers water
22248-79-9 112281-77-3 7696-12-0 148-79-8 111988-49-9 153719-23-4 117718-60-2 59669-26-0 39196-18-4 640-15-3 23564-05-8 62-56-6
47
very bio acc
0 0 1 0
30
max = 1
1 2 1 1
383 384 385 386 387 388 389 390 391 392 393 394
Temephos Tepraloxydim Terbufos Terbutryn Terrazole; Etridiazole Tetrachlorvinphos Tetraconazole Tetramethrin Thiabendazole Thiacloprid Thiamethoxam Thiazopyr Thiodicarb Thiofanox Thiometon Thiophanate-methyl Thiourea
EU EDC (1,2) or C2 & R2 GHS
3383-96-8 149979-41-9 13071-79-9 886-50-0 2593-15-9
111 1
0 1
EU GHS repro (1A ,1B)
378 379 380 381 382
73
EU GHS muta (1A, 1B)
0
4
EU GHS carc (2)
1
11
IARC poss carc
Tembotrione
3
EPA poss carc
335104-84-2
1
EPA prob likel carc
2
377
IARC prob carc
Tefluthrin
EU GHS carc (1A, 1B)
79538-32-2
42
IARC carc
376
1
48
EPA carc
1
27
max = 1
Tebufenpyrad Tebupirimifos
H330
119168-77-3 96182-53-5
0
WHO Ib
374 375
WHO Ia
Pesticide sum of max=1 in Groups 1-4
CAS number
Group 3: Environmental toxicity
1 1
1 1 1
1 1 1 1
33
PAN International List of Highly Hazardous Pesticides - PAN Germany for PAN International - November 2013 Group 1: Acute Toxicity
1 1
1
1
1
1
1 1 0 1 1 1 1 0 1
1 1 1 1 1 1
PAN International list of Highly Hazardous Pesticides - PAN Germany for PAN International - 11/2013
1
1
1 1 1
1 1
1
1 1
1
1
1
1
0 0 1 1 1 0 0 1 1 0 0 0
1
24
0
7
1
X
max = 1
1 1
1 1 1 1 0 1 1 1 0 0 1 1
115
POP
1 1 1
50
See note below the table
1 1
40
PIC
1 1
18
Montr Prot
90
Group 4: Conventions
max = 1
20
highly toxic bees
4
very pers water sedi
47
very pers water
30
very bio acc
EU EDC (1,2) or C2 & R2 GHS
111
max = 1
EU GHS repro (1A ,1B)
73
EU GHS muta (1A, 1B)
0 0 0 0 0 0 0 0 0
4
EU GHS carc (2)
2 1 1 1 2 1 1 1 1
11
IARC poss carc
0
3
Group 3: Environmental toxicity
EPA poss carc
1
1
EPA prob likel carc
1
0 1 0 0 0 0 0 0 0 1 0 0
IARC prob carc
1
EU GHS carc (1A, 1B)
42
IARC carc
48
EPA carc
52-68-6 3380-34-5 41814-78-2 81412-43-3 1582-09-8 126535-15-7 26644-46-2 131983-72-7 83657-22-1
2 2 2 2 1 1 1 2 1 1 1 1
27
max = 1
408 409 410 411 412 413 414 415 416
Thiram Tolylfluanid Topramezone Tralkoxydim Tralomethrin Triadimefon Triadimenol Tri-allate Triasulfuron Triazophos Tribenuron methyl Tribufos Tributyltin compounds Trichlorfon Triclosan Tricyclazole Tridemorph Trifluralin Triflusulfuron-methyl Triforine Triticonazole Uniconazole
H330
137-26-8 731-27-1 210631-68-8 87820-88-0 66841-25-6 43121-43-3 55219-65-3 2303-17-5 82097-50-5 24017-47-8 101200-48-0 78-48-8 nocas 8
0
WHO Ib
395 396 397 398 399 400 401 402 403 404 405 406 407
WHO Ia
Pesticide sum of max=1 in Groups 1-4
CAS number
Group 2: Long term effects
1 0 0 0 0 0 0 0 0 0 0 0
0
0
1 0 1 0 1 0 0 1 0
0 0 0 0 0 0 0 0 0
34
PAN International List of Highly Hazardous Pesticides - PAN Germany for PAN International - November 2013 Group 1: Acute Toxicity
1
1
1
1 1
PAN International list of Highly Hazardous Pesticides - PAN Germany for PAN International - 11/2013
1 1
1 1
1
24
0
7
1 1 0 0 1 1 0 0 0 0
max = 1
1
115
POP
1 1
50
See note below the table
1
40
PIC
1
0 0 1 1 0 1 0 1 1 0
18
Montr Prot
90
Group 4: Conventions
max = 1
20
highly toxic bees
4
very pers water sedi
47
very pers water
30
very bio acc
EU EDC (1,2) or C2 & R2 GHS
111
max = 1
EU GHS repro (1A ,1B)
73
EU GHS muta (1A, 1B)
4
EU GHS carc (2)
1
11
IARC poss carc
1
3
Group 3: Environmental toxicity
EPA poss carc
1 1
1
EPA prob likel carc
1
0 1 0 1 0 1 1 0 1 1
IARC prob carc
1
EU GHS carc (1A, 1B)
42
IARC carc
48
EPA carc
27
max = 1
1 2 1 2 1 3 1 1 2 1
H330
Validamycin Vamidothion Vinclozolin Warfarin XMC zeta-Cypermethrin Zinc phosphide Zineb Ziram Z-Phosphamidon
WHO Ib
37248-47-8 2275-23-2 50471-44-8 81-81-2 2655-14-3 52315-07-8 1314-84-7 12122-67-7 137-30-4 23783-98-4
0 417 418 419 420 421 422 423 424 425 426
WHO Ia
Pesticide sum of max=1 in Groups 1-4
CAS number
Group 2: Long term effects
0 0 0 0 0 0 0 0 0 0
35
Explanatory notes WHO 1a:
Extremely hazardous (Class 1a) according to World Health Organisation
WHO 1b:
Highly hazardous (Class 1b) according to World Health Organisation
H330
‘Fatal if inhaled’ hazard classification according to the Globally Harmonised System (GHS)
max = 1
This active ingredient meets at least one criteria in this Group
EPA carc
Human carcinogen according to EPA
IARC carc EU GHS (1A, 1B):
Human carcinogen according to IARC Known or presumed human carcinogens (1A or 1B) according to EU GHS Regulation 1272/2008/EC
EPA prob/likel carc
Probable/ Likely carcinogen according to EPA
IARC prob carc
Probable carcinogen according to IARC
EPA poss carc:
Possible carcinogen according to EPA
IARC poss carc:
Possible carcinogen according to IARC
EU GHS (2): EU GHS muta (1A, 1B)
Suspected human carcinogen (Cat. 2) according to EU GHS Regulation 1272/2008/EC Substances known to induce heritable mutations or to be regarded as if they induce heritable mutations in the germ cells of humans. Substances known to induce heritable mutations in the germ cells of humans’ (Category 1A or 1B) according to EU Regulation 1272/2008/EC
EU GHS repro (1A, 1B):
Known or presumed human reproductive toxicant according to EU GHS Regulation 1272/2008/EC EU EDC (1,2) or C2 & R2 GHS: Endocrine disruptor or potential endocrine disruptor according to EU Category 1 or Category 2 or GHS Cancer 2 AND EU reproductive toxicity Very bio acc:
Very bioaccumulative according to REACh criteria (BCF >5000)
Very pers water:
Very persistent/water according to REACh criteria (Halflife > 60 days)
Very pers water sedi:
Very persistent in water/sediment according to REACh criteria (Halflife > 180 days)
Highly toxic bees:
Hazard to ecosystem services – Highly toxic to bees (<2 µg/bee) according to U.S. EPA as listed by FOOTPRINT data
Montr Prot:
Ozone depleting chemical according to the Montreal Protocol
PIC:
Listed in Annex III of the Rotterdam Convention
POP:
Listed in Annex III of the Stockholm Convention
PAN International list of Highly Hazardous Pesticides - PAN Germany for PAN International - 11/2013
36