ACRONYMS ALS: amyotrophic lateral sclerosis motor neuron disease
CMT: Charcot-Marie-Tooth disease (inclusive of all forms) peripheral neuropathy
FSHD: facioscapulohumeral muscular dystrophy primary myopathy
GBS: Guillain-Barré syndrome LGMD: limb girdle muscular dystrophy primary myopathy
MD: myotonic muscular dystrophy, types 1 and 2 primary myopathy (channelopathy)
PPS: postpolio syndrome SMA: spinal muscular atrophy motor neuron disease
by Gregory
T. Carter MD, MS
Neuromuscular diseases (NMDs) include a variety of conditions that affect components of a motor unit (motor neuron cells, nerve, neuromuscular junction, and muscle fibers), sensory and autonomic nerves, or their supportive structures, such as myopathies (polymyositis, dermatomyositis, inclusion body myositis, muscular dystrophies, and metabolic myopathies), diseases of the neuromuscular junction (myasthenia gravis, Eaton-Lambert syndrome), and neuropathies (Charcot-Marie-Tooth disease [CMT ], Guillain-Barré syndrome [GBS]). The major diseases referenced most often in this paper are listed under Acronyms (above). These are not rare diseases, and most clinicians will encounter some patients with a NMD in their clinical practice.1 abstract:
12 | PWJ | www.painweek.org
Q1 | 2014