October 2017 innovate

October 2017

INNOVATE OKC Innovates: Big Data Symposium

A publication of the Oklahoma Health Center Foundation

The Oklahoma Health Center

Welcome to our green publication, Innovate. This communication tool is brought to you by the Oklahoma Health Center Foundation to promote the happenings at the Oklahoma Health Center and bring you the latest information about our member organizations.

Since 2000, more than $534 million in construction costs has been invested on the campus. In 2016, the OHC employee and OUHSC student count is approximately 18,000 making it one of the largest employers in Oklahoma.

The Oklahoma Health Center is the premier address for research, patient care, education, technology and community health support. Located conveniently in the heart of Oklahoma City, this remarkable 325-acre complex unites 22 organizations ranging from cutting-edge biotechnology companies to government, education, patient care and community support institutions. As the second largest concentration of employees in Oklahoma, this health care consortium touts a $3 billion capital infrastucture that is continually growing to meet the needs and demands of the people. A recent study determined the Oklahoma Health Center has a more than $3 billion annual economic impact on the community.

800 N. Research Parkway, Suite 400 Oklahoma City, OK 73104 Phone: (405) 271-2200 Website: www.oklahomahealthcenter.com Follow Us on Facebook and Twitter @OKHealthCtr

2

INSIDE Moleculera Labs to Receive Patent for PANDAS/PANS Blood Test Panel Company Based on OUHSC Research

4-5 6

OMRF opens state’s first germ-free mouse research facility

Big Data Symposium

9 Next Mind Meld November 30

16 Oklahoma Health Center Campus Map

OHCF Members

14-15 18-39

3

Moleculera Labs to Receive Patent for PANDAS/PANS Blood Test Panel Company Based on OUHSC Research

Madeleine Cunningham, Ph.D., a researcher at the University of Oklahoma College of Medicine.

Craig Shimasaki, Ph.D., president and CEO of Moleculera Labs

4

In spring 2015, Kate was an easygoing, friendly second-grader who did well in school and loved to play with her friends.

Aside from several strep infections, she had never really been sick. But in one week’s time, that began to change drastically. She began to feel sick to her stomach and, more disturbingly, she became extremely anxious. She was suddenly afraid of fires and tornadoes, and she feared that someone was poisoning her food.

She developed an extreme fear of thunderstorms and bugs, and she became petrified to go to school. She once tried to jump out of a moving car.

“It was horrible. Literally from one week to the next, our daughter changed from a normal child into someone completely different,” said Kate’s mother, Meg Reynolds.

That was just the beginning of a difficult journey for the Reynolds family, but as tough as it was, they were among the lucky ones. Kate’s doctor told the family about something called Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococci (PANDAS), an autoimmune condition initially triggered by strep infections, which disrupts normal neurologic activity. PANDAS and a related condition, PANS, Pediatric Acute-Onset Neuropsychiatric Syndrome, are a major focus for Madeleine Cunningham, Ph.D., a researcher at the University of Oklahoma College of Medicine.

Children suffering from PANDAS/PANS often are misdiagnosed for years, or treated with anti-psychotics, which aren’t effective for autoimmune-based disorders.

But the Reynolds family was fortunate. When Reynolds was talking with her parents about the dramatic change in Kate’s behavior, she told them that their doctor mentioned PANDAS. As it turned out, Reynolds’ father, Robert Calcaterra, Ph.D., sits on the board of directors for Moleculera Labs, the Oklahoma City-based company that has licensed Cunningham’s clinical assays used by physicians to help diagnose PANDAS/PANS. Kate was indeed diagnosed with PANDAS. She started antibiotics and began cognitive behavioral therapy to learn coping techniques for her obsessive thoughts; about nine months later, she was mostly back to normal.

“It was a long road, but from what I’ve heard, our experiences were minor even though our lives were turned upside down,” Reynolds said. “We could have been like some other parents who went years before someone mentioned it or they finally found a doctor who knew about it.”

Those are the stories that spur Cunningham to continue her research, and for Craig Shimasaki, Ph.D., president and CEO of Moleculera Labs, to continue building the company. This year, Moleculera has reached a significant milestone: In the next few months, it anticipates being awarded a patent that protects the panel of five blood tests used as an aid in diagnosis. The company also trademarked the name “Cunningham Panel.” In the difficult journey of commercializing research, the patent is a major achievement.

“We are the only laboratory in the world that provides this panel,” Shimasaki said. “The patent not only protects our intellectual property, but it attributes value to what we’re doing as unique.”

Moleculera has grown significantly since it began. Physicians in 49 of the 50 states, as well as countries around the world, have ordered more than 5,000 tests to aid in the diagnosis of PANDAS/PANS, Shimasaki said. The company’s office receives countless letters and pictures from grateful parents, some of whom were close to institutionalizing their children until they discovered the underlying cause was an autoimmune problem. Cunningham, too, advocates for the families who have not yet received the answers that her tests can potentially provide.

“I am so pleased at this next stage of growth for Moleculera Labs,” said Cunningham, who is co-founder and chief scientific officer for the company. “My hope has always been that my research would be able to help patients and families who are suffering. My work is built on the success of many others in the field, including Dr. Susan Swedo of the National Institute of Mental Health, and I am grateful to be a part of this important field of study.”

Moleculera’s new patent also is a success for OU’s Office of Technology Development (OTD), which helps researchers protect and commercialize their discoveries.

OTD officials, along with James Tomasek, Ph.D., vice president for research at the OU Health Sciences Center, have worked diligently for years to turn Cunningham’s academic research into a commercial company that can help patients. Although the process is long and fraught with potential pitfalls, Moleculera has grown into a solid company that is helping people worldwide while also contributing to Oklahoma’s economy.

“Starting a new company is never easy,” said Jim Bratton, executive director of OTD and OU assistant vice (Continued on page 40) 5

OMRF opens state’s first germ-free mouse research facility

6

The Oklahoma Medical Research Foundation recently opened its new Gnotobiotic Mouse Core (GMC) Facility.

The center is the first of its kind Oklahoma, offering medical researchers the ability to raise and study mice in an environment free of germs and microbes. One of only a handful of “gnotobiotic” research centers around the country, the new facility will play a key role as state scientists seek to understand how the microscopic organisms that populate our world affect our health.

“This capability is a powerful tool for researchers, as it allows them to observe the effects of specific microbes and their roles in the development of diseases,” said Sai Tummala, D.V.M., OMRF’s Associate Vice President of Comparative Medicine and Attending Veterinarian, who led this initiative The facility consists of modular flexible film isolators (plastic bubbles) that are home to colonies of specially bred mice. Here, the animals can live their entire lives in a germ-free environment without the trillions of microbes that exist in and on humans and animals under ordinary circumstances. The modular setup provides flexibility in increasing the number of isolators as demanded by research projects.

Access to the GMC requires entering through a barrier facility, where personnel must gown up in sterile clothing and undergo an air shower, which removes any remaining pathogens. Likewise, everything that comes into the facility—like food, water and bedding for the mice—must first be sterilized. The comparative medicine team has developed standard operating procedures to monitor and maintain sterility for the GMC. The sterile environment allows researchers to compare germ-free animals with those raised normally. It also enables them to introduce a single microorganism or select group of microbes to study how they affect the health of the animal.

This field of research has taken on increasing importance as scientists have recognized the roles that microorganisms play in digesting food, fighting off illness and in controlling disease. In particular, scientist have found that tiny organisms living in our digestive tracts may be key players in obesity, diabetes, autism, asthma and a variety of autoimmune diseases.

“We anticipate this new facility to spark substantial interest in the local scientific community and also attract new talented scientists to the region,” said Tummala.

Located on the OMRF campus, the center operates as a shared research facility available to researchers across the state. Initial funding was provided by a grant from the Presbyterian Health Foundation.

“This facility will amplify the impact of research at the Oklahoma Health Center and is another example of OMRF leading the way in broadening scientific discovery that improves the lives of all Oklahomans,” said PHF President Tom R. Gray, III. The new center’s first research project, led by OMRF scientist Umesh Deshmukh, Ph.D., will study the role that microbes play in Sjögren’s syndrome, an autoimmune disease characterized by dry eyes and mouth.

Deshmukh will investigate why mouse models genetically engineered to show symptoms of Sjögren’s experienced significant changes to their microbiomes when they were relocated from Charlottesville, Va., to Oklahoma City. The mice stopped exhibiting Sjögren’s symptoms at OMRF, alerting researchers that environmental factors must have impacted the mice and their ability to develop the disease.

Deshmukh said this is important because it tells scientists that even if you have genetic susceptibility to a disease, it doesn’t mean you will develop it. A wide spectrum of environmental factors can change the microbiome, he said, for better or for worse.

“This new facility is critical for our research, because it will give us the ability to identify which microbes are responsible for influencing the development of or resistance to this disease,” said Deshmukh. “This project would not be possible without the availability of this germ-free environment. It’s a very exciting addition to our campus that will prove incredibly beneficial in a number of projects.”

7

How to have a safe Halloween for kids with allergies & asthma For children with allergies and asthma, Halloween can be a real bummer. Something as innocent as an ingredient in candy or in Halloween make up could cause a life-threatening allergic reaction. How can you keep your children safe this year?

The Teal Pumpkin Project is now in its fourth year as a national awareness campaign led by the Food Allergy Research & Education (FARE) set up as a way to create a happier, safer Halloween. The Teal Pumpkin Project encourages people to provide non-food treats on Halloween.

In the U.S., one in 13 children have at least one food allergy and anaphylactic reactions have climbed dramatically in recent years. By posting a FARE flyer at your home or a teal pumpkin on your porch, families will know that this is an allergy-free stop during trick or treat night.

How can you participate as a Teal Pumpkin supporter?

little goblin. You can drop off safe treats to your neighbors so your child can go trick-or-treating in your neighborhood.

Teach your child to say no thank you to homemade treats or ones that might cause an allergic reaction.

If you suspect your child may have allergies or asthma, make an appointment by calling 405/235-0040 with an Oklahoma Allergy & Asthma Clinic allergist for an evaluation.

Provide non-food treats for trick-or-treaters: glow sticks, bracelets, or necklaces, pencils, pens, crayons or markers, bubbles, Halloween erasers or pencil toppers, mini Slinkies, whistles, kazoos, or noisemakers, bouncy balls, finger puppets or novelty toys, coins, spider rings, Vampire fangs, mini notepads, playing cards, bookmarks, stickers or stencils.

You can also have candy at your home for those who are not food allergic – just keep it in a separate container.

Costumes are also a fun part of Halloween. For children with asthma, it might be better to skip wearing a mask so it won’t obstruct breathing. If your child has eczema or other skin allergy condition, consider using hypoallergenic makeup.

Always test a small area of skin first to see if there is a skin reaction before using makeup.

Parents, be prepared before you go trick-or-treating with your kids. Carry a fully charged cell phone, emergency epinephrine and a bag of allergy-safe food treats for your

8

For information about the Teal Pumpkin campaign, visit www.foodallergy.com

Big Data Symposium Draws 200 participants The Oklahoma Health Center Foundation and the Greater Oklahoma City Chamber hosted OKC Innovates: Big Data Symposium on Oct. 18 at the Embassy Suites-Downtown Medical Center. Attendees represented a cross section of businesses and academia. Five panel discussions featured data experts on Acquiring Data, Storing Data, Interrogating Data and Adding Value to Data.

Four speakers spoke during each panel discussion.

After each panel presentation, attendees were encouraged to collaborate at their tables, and then a question and answer session was held.

Serving as moderator was Dave King, Exaptive CEO. Kicking off the symposium was Dr. Kelvin Droegemeier, secretary of Science and Technology, State of Oklahoma who spoke on the impact of big data and the importance of cross-pollination between businesses.

Speakers were from OMRF, FAA, Flogistix, Devon Energy, Love’s Travel Stops, American Fidelity, Oseberg, Boeing, OU Health Sciences Center, ARL/DNA Solutions, Oklahoma City University, Oklahoma State University, and Baker Hughes GE. A networking reception was held after the event.

Go to the Oklahoma Health Center Foundation website www.oklahomahealthcenter.com to watch the symposium online and to download the PowerPoint presentations.

Dr. Adam Rasheed, Baker Hughes GE, spoke on “The Challenge of Subject Matter Expertise and Data-Sciece Expertise - A Call to Action.”

9

Oklahoma School of Science and Mathematics receives major donation from one of the country’s top companies - Amazon

By Paul Folger, KOCO-TV Amazon donated $15,000, which will help the school support its science, technology, engineering and math (STEM) programs and provide wireless internet for all of the students. The school has about 150 students from all 77 Oklahoma counties.

“All the students live here on campus,” School President Dr. Frank Wang said. “The classes we teach are at college level. Most of our faculty have a Ph.D. in their field.”

The school also provides early basic training for hightech jobs.

“We think Amazon represents the kinds of things we are trying to achieve,” Wang said.

The donation will help make up for the budget cuts the school has felt from the state. Amazon officials said the Oklahoma School of Science and Mathematics is just a good fit for them.

10

OSSM receives $15,000 from Amazon, pictured are left to right: Jerry Burger, OSSM trustee; Dan Little, OSSM trustee; Oklahoma City Mayor Mick Cornett; Erin Shipp, Amazon; Dr. Wang, OSSM president; Susan Winchester, OSSM trustee; Catherine Armitage, OSSM board member, and Ron Mashore, OSSM board member.

“We are new to the Oklahoma City area, and it’s exciting to be a part of what is going on in Oklahoma City,” said Erin Shipp, with Amazon.

Oklahoma City officials recently Amazon made a pitch to be the new second headquarters. Authorities said it’s too early to tell which cities the company is considering.

Bedlam Blood Battle Begins in Stillwater Win from Within! October 30 – November 3 As the legendary Bedlam Blood Battle is set to begin in Stillwater, which Oklahoma team will save the most lives?

Oklahoma State University will team up with Oklahoma Blood Institute for blood drives at three campus locations Monday, October 30, through Friday, November 3, 2017: • Cowboy Underground at the Student Union, 10 a.m. – 4 p.m.

• University & Monroe (Bloodmobile), 1 p.m. – 6 p.m.

• Kerr-Drummond Plaza (Bloodmobile), 1 p.m. – 6 p.m.

Donors will get free pizza and an orange OSU “Win from Within” Bedlam T-shirt.

OSU participants can text OBI4OSU to 59925 during the blood drive for a chance to win a Yeti cooler. They will receive text messages about blood drive information and updates on Bedlam Blood Battle scores. Participants can track their school’s score on social media using the hashtag #bedlambloodbattle.

Donors can also text OBIBEDLAM to 59925 by October 29 to be entered in a contest to win a pair of Bedlam game tickets for the November 4 game in Stillwater. Entrants must also like Oklahoma Blood Institute’s Facebook page to win at facebook.com/oklahomabloodinstitute or facebook.com/oklahomabloodinstitutetulsa.* “We are happy to do our part with Oklahoma Blood Institute,” said Mike Holder, OSU Athletic Director. “Our Cowgirls and Cowboys understand the need for this effort and have always responded in great numbers.”

The school with the most blood drive participants wins the Bedlam Blood Battle trophy and bragging rights.

The Cowboys have the chance to keep the trophy in Stillwater by participating in the upcoming blood drive.

“Last fall, the Cowboys edged out the Sooners for the first time since 2013, and by only 66 blood drive participants,” said John Armitage, M.D., president and CEO of Oklahoma Blood Institute. “But no matter which school wins, patients in Oklahoma are truly the winners.”

Healthy adults age sixteen and up are encouraged to donate.** Oklahoma Blood Institute, the nation’s 9th largest non-profit blood center, provides every drop of blood for more than 160 hospitals and medical facilities statewide.

Appointments are not required, but to make one go to obi.org or call 877.340.8777. *Official contest rules can be found at obi.org. **16-year- olds must weigh at least 125 pounds and provide signed parental permission; 17-year-olds must weigh at least 125 pounds; 18+ year-olds must weigh at least 110 pounds.

11

Easter Seals Oklahoma Changes Name To Wovenlife WovenLife, Inc. is the new name chosen for the nonprofit that has served Oklahomans of all abilities since 1925. Formerly known as Easter Seals Oklahoma, the nonprofit officially transitions to WovenLife, Inc. on Thursday, August 31, 2017.

“With this new change, we will refocus to become completely concentrated on the local needs of our community, ensuring every dollar raised goes back into our community to serve Oklahomans,” said Paula Porter, President and CEO. WovenLife remains committed to serving the needs of people of all ages and abilities through its inclusive Child Development Program, Adult Day Center, unique intergenerational programming, therapy services; which include behavioral, speech and occupational therapy, educational programming and financial assistance program.

“WovenLife refers to the diversity of services we provide, and the weaving of intergenerational learning and care of young and old, abled and differently abled, we are where their paths cross,” said Porter about the new organization name.

WovenLife provides services to children and adults with disabilities and other special needs and support to their families. Services include a child development

program, adult day center, therapy services, screenings and financial assistance. WovenLife is located at 701 NE 13th Street, Oklahoma City, OK 73104. For more information, please visit www.wovenlifeok.org .

Dillard’s Offers Exclusive Southern Living Christmas Cookbook to Benefit Ronald McDonald House Charities This holiday season cook up something delicious out of the Southern Living Christmas Cookbook available now in all Dillard’s stores, as well as online at www.dillards.com. All sales from the cookbooks in the Dillard’s Oklahoma City market will benefit Ronald McDonald House Charities Oklahoma City (RMHC-OKC) to help keep families of sick children close to each other and the medical care they need. For the tenth time, Dillard’s is offering a special custom edition of the Southern Living Christmas Cookbook to benefit Ronald McDonald House Charities. This exclusive hardbound cookbook is filled with more than 280 pages with over 175 all-new recipes, as well as decorating ideas for Christmas plus seasonal gatherings. This “can’t-miss” cookbook is available for only $10.

12

Now in its 24th year of support, Dillard’s has raised more than $13.6 million nationwide to benefit RMHC. “Our con(continued on page 40)

Pioneering Scientist Ralph DeFronzo Named 2017 Hamm Prize Laureate Dr. DeFronzo spearheaded study of insulin resistance and diabetes drug metformin Imagine how different the lives of the one in three Oklahomans who have diabetes or prediabetes would be if this disease were cured, and the billions of dollars in annual health care costs saved.

Advancing progress toward that cure was the impetus for establishing the $250,000 Harold Hamm International Prize for Biomedical Research in Diabetes, the largest of its kind in the world, awarded by Harold Hamm Diabetes Center at the University of Oklahoma.

The Hamm Prize recognizes and encourages lasting advances in the field of diabetes research. It is awarded to an individual who has either demonstrated lifelong contributions to the field or realized a singular advance, especially in leading toward a cure.

The 2017 recipient, Dr. Ralph DeFronzo, is directly responsible for many of the advances achieved in diabetes over the last 50 years. He was a leader in developing the concept of insulin resistance, the defining characteristic of Type 2 diabetes, resulting in novel ideas about

Dr. DeFronzo receives the honor from (right) Harold Hamm and David L. Boren (middle). the development and progression of diabetes.

DeFronzo led the U.S. development of metformin, the first-line medication for treatment of diabetes, and ushered it through FDA approval in 1995. More recently, he discovered a new approach to diabetes treatment that targets glucose reabsorption in the kidneys. This work led to the development and approval of other widely used drugs, including dapagliflozin, empagliflozin and canagliflozin.

DeFronzo is the author of 750 publications dating back to 1967. He currently serves as professor of medicine and chief of diabetes in the Long School of Medicine at University of Texas Health San Antonio, where he has been on faculty since 1988. “My hope in awarding this unprecedented international research prize is that we would ignite worldwide scientific interest and innovation to find a cure for diabetes in this generation,� said Harold Hamm, chairman and CEO of Continental Resources Inc., who provided the endowment to establish the prize, following his generous lead gift in 2007 for the establishment of Harold Hamm Diabetes Center.

Hamm’s endowment of the prize provides for its awarding in the future in perpetuity. This endowment repre-

Dr. Ralph DeFronzo

(continued on page 40)

13

Oklahoma Health Center Campus *Member Organizations Oklahoma Health Center Foundation

1. American Red Cross of Central Oklahoma 2. Dean McGee Eye Institute* 3. Department of Veterans Affairs Medical Center 4. WovenLife* 5. Office of the Chief Medical Examiner 6. Oklahoma Allergy and Asthma Clinic* 7. Oklahoma Blood Institute* 8. Children’s Hospital Foundation* 9. Oklahoma Medical Research Foundation* 9a. OMRF Research Tower* 9b. OMRF Bell Building* 9c. OMRF – Acree-Woodworth Building* 9d. OMRF – Massman Building* 10. Oklahoma School of Science and Mathematics* 11. Oklahoma Department of Health* 12. General Electric Global Research* 13. Department of Human Services 14. OU Medical Center* A. Professional Office Building B. OU Medical Center C. The Children’s Hospital D. Oklahoma Transplant Center E. OU Medical Center Surgical Center 15. OU University Research Park 655 Conference Center Pall Forte Oklahoma Business Roundtable Oklahoma State Regents OneNet OTRC OU Medical Center Financial Services OU Medical Center Marketing Presbyterian Health Foundation* Potts Family Foundation Pure Protein SIWA ViewSolid, Inc. 755 DNA Solutions COARE Biotech Haus Spaus Department of Veterans Affairs Medical Center URP Management Office MedEncentive Moleculera NewSpin360 Nova Venture Services, LLC OCAST*

14

OptumRX Oklahoma Tobacco Research Center OUHSC Center for Intelligence and National Security* Potawatomi Federal Solutions Purmabiologics Sigma Blood Systems Sylvia Bottomley 800 Biolytx Pharmaceuticals Corp.

Charlesson Comp. Risk Management Crisalis Cytovance Biologics EyeCRO Inoveon Oklahoma Health Center Foundation* OU Health Sciences Center* Transtimulation Research, Inc. Zanek 825 Camilles Sidewalk Cafe Richey’s Grill 840 ARL Bio Pharma* Cytovance Biologics DNA Solutions* Gear Up i2E, Inc. LabCorp Office of Educational Quality and Accountability Oklahoma State Regents for Higher Education OU Physicians - Reproductive Medicine* OUHSC Financial Services* OUHSC Payroll* Selexys Pharmaceuticals 865 Accele Biopharma ARL Bio Pharma* Drik LLC Michael F. Price College of Business Miles Associates OUHSC Office of the Vice President for Administration and Finance* OUHSC Facilities Management* OUHSC Office of the Fire Marshal* OUHSC Grants and Contracts* OUHSC Office of Research Administration* OUHSC Vice President for Research* OUHSC Vivarium* University Health Club 885 Cytovance Biologics

16. University of Oklahoma Health Sciences Center* A. Allied Health Practice Center B. Basic Sciences Education Building C. Campus Police Station D. College of Allied Health E. College of Dentistry F. Biomedical Sciences Building G. Fran and Earl Ziegler College of Nursing H. Henry D. & Ida Mosier College of Pharmacy I. College of Public Health J. David L. Boren Student Union K. Don E. Hogg Greenhouse L. G. Rainey William Pavilion M. Harold Hamm Diabetes Center N. O’Donoghue Research Building - OU Medical Center Senior Health Clinic O. Stephenson Cancer Center P. Child Study Center Q. OU Physicians Building* R. OU Physicians Dermatology* S. OU Physicians Family Medicine Center* T. Robert M. Bird Library and Graduate College U. OUHSC Technology Center V. Service Center Building W. Stanton L. Young Biomedical Research Center X. Steam and Chilled Water Plant Y. University Health Club Z. University Village AA. OUHSC Faculty House BB. OUHSC (Formerly Oklahoma City Clinic) CC. OU Children’s Physicians 16. Oklahoma State Department of Mental Health and Substance Abuse Services* (located off campus) 17. University Hospitals Authority and Trust* 18. Ronald McDonald House Charities of Oklahoma City* 19. Ronald McDonald Family Room (in The Children’s Hospital)* 20. Ronald McDonald House II (in Garrison Tower)* 21. Andrews Academic Tower (UHAT)* 22. Embassy Suites Downtown/Medical Center* 23. OK Kids Korral 24. Oklahoma Employees Credit Union* (located off campus)

15

MIND MELD Mind Meld Networking Event – sharing ideas, resources and support to promote science, research and development Free Networking event • Food and Drink provided to share ideas and collaboration Thursday, November 30 5:30-7:30 p.m.

Hosted by Dean McGee Eye Institute, 608 Stanton L. Young Blvd., Oklahoma City Mind Meld mirrors the creative, optimistic and successful synergies the new proposed Innovation District will bring to the area surrounding the Oklahoma Health Center. It offers insight and opportunity to discover connections that can propel your endeavors and the research/projects you are working on.

In a casual, after-work atmosphere, enjoy free light bites and adult beverages, while you meet and learn about what others are working on in our Innovation District. From 5:30 to 6:00 pm, guests will enjoy the happy hour portion of the event. The event itself will be held from 6 to 7 pm. At 7 pm, guests will have the ability for post-networking until 7:30 and to meet with anyone they didn’t have an opportunity to previously talk with.

Bring your 90-second elevator speech and connect with your fellow inhabitants of the Innovation District over the course of an interesting hour. Please bring business cards for distribution to approximately 30 other attendees.

RSVP https://www.eventbrite.com/e/mind-meld-tickets-37857849848?aff=utm_source%3Deb_email%26utm_ medium%3Demail%26utm_campaign%3Dnew_event_email&utm_term=eventurl_text Scenes from the Mind Meld Sponsored by University Hospitals Authority and Trust Sept. 7th

16

ARL Bio Pharma, Inc.

18

Children’s Hospital Foundation

19

Dean McGee Eye Institute

20

DNA Solutions, Inc.

21

Easter Seals Oklahoma

22

Oklahoma Allergy & Asthma Clinic

23

Oklahoma Blood Institute

24

Oklahoma Center for the Advancement of Science and Technology

25

Oklahoma Health Center Foundation

26

Oklahoma Department of Mental Health & Substance Abuse Services

27

Oklahoma State Department of Health

28

Oklahoma Medical Research Foundation

29

Oklahoma School of Science & Mathematics

30

OU Medical Center

31

OU Physicians

32

Presbyterian Health Foundation

33

Ronald McDonald House Charities® of Oklahoma City

34

University Hospitals Authority and Trust

35

University of Oklahoma Health Sciences Center: College of Allied Health • College of Dentistry College of Medicine • College of Nursing College of Pharmacy • College of Public Health Graduate College • Stephenson Cancer Center Harold Hamm Diabetes Center

36-37

Member Organizations

Associate Members Oklahoma Employees Credit Union

38

Embassy Suites

39

17

Member

Tom Kupiec, Ph.D., President and CEO 840 Research Parkway Suite 546 Oklahoma City, OK 73104 Phone: (405)271 1144 Website: www.arlok.com ARL Bio Pharma is a contract laboratory that provides analytical and microbiological testing services for the pharmaceutical industry. Our laboratory works with pharmaceutical companies, compounding and hospital pharmacies, drug manufacturers, academic institutions, and research scientists bringing excellence to pharmaceutical sciences.

ARL recognizes the importance of providing quality testing services. With over 100,000 formulations tested, we assist our clients in providing quality drug products to their patients.

Our services include: full analytical and research and development support, stability and compatibility studies, micro-

18

biology testing, dissolution testing, microbial identification, bioequivalence studies, and pre-clinical and clinical support.

ARL also assists local and government agencies and regulatory bodies with forensic drug investigations including: drug diversion testing, chemical and biological analysis, complaint sample testing, litigation support, product contamination and patent infringement.

Contact ARL for more information on analytical, microbiological analysis and forensic drug investigation services at 800-393-1595.

Member

Kathy McCracken, Executive Director 6501 Broadway Extension, Suite 190 Oklahoma City, OK 73116 Phone: (405) 271-2260 Toll Free: 888-229-KIDS Tax ID: #73-1200262 Website: www.chfKids.com Children’s Hospital Foundation is the only nonprofit organization in Oklahoma whose sole focus is the advancement of pediatric research and education while supporting specialized clinical care for Oklahoma’s children. Since its inception in 1983, Children’s Hospital Foundation has raised and leveraged matching funds to create more than $110 million for pediatric research, quality specialized clinical care and education programs. Many of these endeavors include collaborative projects with the University of Oklahoma College of Medicine and Children’s Hospital at OU Medical Center in Oklahoma City.

All funds raised in Oklahoma stay in Oklahoma so that families don’t have to leave the state to receive specialized care. CHF supports pediatric specialists who treat more than 225,000 patient visits every year including children in all 77 counties and no child is ever turned away, regardless of ability to pay.

CHF is currently recruiting endowed chairs and has naming opportunities available. For more information, contact Children’s Hospital Foundation toll free 888-229-KIDS (5437) or (405) 271-2260.

Current program and research focus areas include: • Infectious disease • Arthritis • Education • At-risk newborns • Diabetes-Obesity • Digestive health • Cancer • Genetics • Community pediatrics • Surgery & Emergency • Autism-ADHD-Down Syndrome • Lung, kidney and heart disease • Adolescent medicine • Eating disorders • Behavioral medicine • Child abuse and neglect Funding for their programs is made possible through the efforts of a dedicated volunteer board, thousands of community volunteers and donors. Through endowments and direct support, they are able to recruit and retain nationally and internationally recognized pediatric physician-scientists to direct research, treat patients and train medical students.

19

Member

Gregory L. Skuta, M.D., President and CEO 608 Stanton L. Young Blvd.

Oklahoma City, OK 73104-5065 Phone: (405) 271-6060 Website: www.dmei.org Benchmarks of Dean McGee Eye Institute Excellence The Dean McGee Eye Institute is one of the largest and most respected eye institutes in the United States, providing more than 176,000 patient visits per year from all 77 Oklahoma counties and the surrounding region, and serving more than 8,100 surgical patients annually in its state-ofthe-art ambulatory surgery center.

Twenty of the Eye Institute’s ophthalmologists are listed among the Best Doctors in America.

The University of Oklahoma (OU) College of Medicine’s Department of Ophthalmology, which is housed in the Dean McGee Eye Institute, ranks among the country’s top departments in National Institutes of Health funding and is 12th in the nation in cumulative funding from Research to Prevent Blindness.

The Dean McGee Eye Institute’s residency program (in affiliation with the OU College of Medicine) attracts top medical students from throughout the nation. Resident surgical education has consistently ranked above the 90th percentile nationally. Since 2000, the first-time pass rates on the American Board of Ophthalmology’s written and oral examinations are 100% and 98% respectively with an average score on the written examination at the 80th percentile.

The Eye Institute’s Director of Vision Research is a Past President of the International Society for Eye Research, Past Vice President of the Association for Research in Vision and Ophthalmology (ARVO) and a recipient of ARVO’s prestigious Proctor

20

Medal; two members of the faculty are recent or current directors of the American Board of Ophthalmology; three serve or have recently served on the Board of Trustees of the American Academy of Ophthalmology (AAO); one will be President-Elect of the AAO in 2016; another has recently served as Vice Chair of the Residency Review Committee in Ophthalmology for the Accreditation Council for Graduate Medical Education; and one is the Immediate Past President of the AAO and a Past President of the American Glaucoma Society.

Member

Thomas C. Kupiec, Ph.D., CEO and President 840 Research Parkway, Ste. 551, Oklahoma City, Oklahoma 73104 Toll Free: (866) 362-9778 Phone: (405) 271-6033 Website: www.dnasolutionsusa.com

As a world leader in genetic and human remains testing, our laboratory partners with federal, state, and city government agencies to assist in the processing of forensic casework including the United States Department of Agriculture, Federal Aviation Administration, police agencies, District Attorneys, Public Defenders, and Medical Examiners.

DNA Solutions is a genetic testing laboratory that reveals answers contained within the strands of DNA. Trusted for over 17 years, our dedicated team of scientists utilizes the most advanced technologies to deliver superior, cost effective results for many types of genetic testing including humans, animals, and microbial identification.

DNA Solutions also works with academic and private researchers to develop novel genetic applications and technologies including single nucleotide polymorphisms (SNPs), allele determination, and marker development.

Our laboratory is one of a select few private labs in the United States that has the combination of FBI Quality Assurance Standards, American Association of Blood Banks, and ISO/ IEC 17025 accreditations including our accreditation in Mitochondrial DNA sequencing.

Contact DNA Solutions today if you require DNA Testing at (405) 271-6033 or www.dnasolutionsusa.com.

21

Member

Serving Oklahoma and the southwest since 1925, the Oklahoma Allergy & Asthma Clinic is one of the oldest and largest medical practices in the United States dedicated solely to the treatment of allergy, asthma and immunology.

The Oklahoma Allergy & Asthma Clinic has eight physicians on its medical staff; board certified by the American Board of Allergy & Immunology and are on the teaching faculty at the University of Oklahoma College of Medicine.

The Oklahoma Allergy & Asthma Clinic is one of only a few allergy groups in the United States with a full-time Nurse Practitioner who holds a Doctorate and is a pulmonary disease management coordinator consulting with individual patients about breathing techniques and asthma education.

Also on staff is are two full-time, registered, licensed nurse practitioners.

Almost one-fourth of The Oklahoma Allergy & Asthma Clinic’s patients are referred from outside Oklahoma City and travel many miles for the sophisticated, high-level al-

Scott B. Dennis, MHA 750 N. E. 13th Street Oklahoma City, OK 73104-5010 Phone: (405) 235-0040 Website: www.oklahomaallergy.com Facebook oklahomaallergyandasthmaclinic Twitter @okallergyasthma lergy and asthma care and to participate in the numerous research studies.

The Oklahoma Allergy & Asthma Clinic has a Burkard pollen and mold collection instrument on the roof of its main location and provides the daily counts to the media and the counts are also posted on the website and on social media.

The Oklahoma Allergy & Asthma Clinic has its central clinic location on the Oklahoma Health Center campus. Four full-service satellite clinics are located in Edmond, Norman, Midwest City and Northwest Oklahoma City, adjacent to Mercy Hospital. A new Norman practice building opened in December 2016.

How is an allergist different than a regular physician? An allergist is a doctor who is an expert in the diagnosis and treatment of allergic diseases and conditions. Those conditions include asthma and frequent coughing; hay fever; sinus infections; eye allergies; reactions to food, insect stings and drugs; and immune system problems that might cause frequent infections. You should see an allergist if you have any of these conditions.

More than 50 million people in the United States have these allergic diseases. Although symptoms may not always be severe, allergies and asthma are serious and should be treated that way. Many people with these diseases simply don’t realize how much better they can feel with proper treatment.

An allergist is trained to find the source of symptoms, treat it and help patients feel healthy. After earning a medical degree, the doctor must complete a three-year residencytraining program in either internal medicine or pediatrics.

Then, an allergist completes two or three more years of study in the field of asthma, allergy and immunology.

22

Member

our ability to recruit marrow registrants from ethnically and age-diverse populations.

John Armitage, M.D., President, CEO 1001 N. Lincoln Blvd.

Oklahoma City, OK 73104 Phone: (405) 278-3100 Website: www.obi.org Oklahoma Blood Institute (OBI) is the ninth largest, nonprofit blood center in America. Every drop of blood needed by patients in more than 140 medical facilities in Oklahoma is provided by donors with OBI. This includes exclusive service for every hospital in the metro-OKC area. An average of 700 donors a day is required to meet these needs.

Volunteer blood donors give more than a 287,000 units of blood annually to provide a safe and adequate blood supply. Blood donors with Oklahoma Blood Institute know they are, literally, saving the lives of their friends, family and coworkers, some who may have no idea they will need blood in an urgent situation. One blood donation can save as many as three peoples’ lives.

OBI is responsible for recruiting blood donors, collecting, processing and testing blood components and transporting it to hospitals across our state. Random inspections by the Food & Drug Administration (FDA) confirm the quality of our operations at every donation site. OBI’s perfect record through 36 straight inspections validates our quality exceeding regulatory requirements.

Oklahoma’s first and only umbilical cord blood bank is in the final phases of FDA accreditation at OBI. It is one of only 24 accredited centers worldwide. Expectant mothers of underserved ethnic descent families now have an opportunity to donate cord blood. There is no charge to the parents, and the donation process is simple and painless. During a blessed time in their own lives, this cord blood center enables Oklahoma families to potentially bring life-saving joy to someone else’s.

OBI is a vital link in cell therapy, procuring healthy stem cells for transplants from adult marrow and umbilical cord donations. The future holds great promise as we expand research and treatments partnerships within the healthcare biosciences industry. Cell therapies and regenerative medicine applications are predicted to revolutionize care for the most life-threatening diseases. We are uniquely positioned as a ready-made ‘cell bank’ with hundreds of thousands of combinations of genetic characteristics among our blood donors. These giving people may be offered the opportunity to further make a difference in the lives of others as part of medical research. Oklahoma Blood Institute can accelerate this revolutionary research cost effectively, so that today’s vision more rapidly becomes the reality of life-enhancing, routine medical treatments.

OBI employs 642 Oklahomans and works with 1,200 volunteers and 2,600 blood drive coordinators. Its donor centers are located in Ada, Ardmore, Edmond, Enid, Lawton, Norman, central Oklahoma City (Oklahoma Health Center), north Oklahoma City and Tulsa. Numerous mobile blood drives are conducted in conjunction with businesses, schools and civic groups each week across the state.

Oklahoma Blood Institute is the state’s only affiliate of Be The Match®, the national marrow donor program. For more than 12,000 Americans each year, a marrow or stem cell transplant is the only hope for a cure of a life-threatening blood cancer or other blood disorder. For the past three years, OBI has ranked in the top performance tier, due to

23

Member

Michael Carolina, CEO 755 Research Parkway, Suite 110 Oklahoma City, OK 73104-3612 Local: (405)319-8400 Toll Free: 866-265-2215 In Tulsa: 618 East Third Street, Suite 5 Tulsa, OK 74120 918-576-7650 Website: www.ocast.ok.gov Facebook: www.facebook.com/ocast.ok.gov Twitter: www.twitter.com/ocast The Oklahoma Center for the Advancement of Science and Technology (OCAST) was established in 1987 as the state’s agency for technology-based economic development. OCAST’s mandate is to “expand and diversify Oklahoma’s economy and provide new and higher quality jobs for Oklahomans” by encouraging “. . . the development of new products, new processes and

24

whole new industries in Oklahoma.” (O.S. 74, Sections 5060.1a and 5060.2A) MISSION To foster innovation in existing and developing businesses • by supporting basic and applied research • by facilitating technology transfer between research laboratories and businesses • by providing seed capital for innovative firms in the development of new products or services • by helping Oklahoma’s small and medium-sized manufacturing firms become more competitive through increased productivity and modernization (O.S. 74, Section 5060.3) VISION OCAST funds cutting-edge science and technology through processes that are recognized nationally and internationally for demonstrating excellence, objectivity and economic impact. OCAST’s vision is continued growth and vitality of its basic premise of facilitating collaborations between state government, universities, start-up companies and established large-scale firms to develop an entrepreneurial environment which supports technologybased economic development. OCAST’s strategy includes technologies such as biosciences, information technology, sensors and electronics, advanced materials, energy and alternative fuel sources. Achieving this vision will result in continued growth of advanced technology companies in the state thereby increasing Oklahoma’s global competitiveness, per capita income and quality of life.

Member

Terri White ODMHSAS Commissioner 2000 N. Classen Blvd, Ste E600 Oklahoma City, OK 73106 Phone: (405) 522-3908 Website: www.odmhsas.org

The Oklahoma Department of Mental Health and Substance Abuse Services is responsible for providing services to Oklahomans who are affected by mental illness and substance abuse. In fiscal year 2008, the department provided services to 64,465 individuals – an increase of nearly 3,600 individuals over the previous year.

The demand for public mental health services exceeds the capacity of the current treatment system. This has always been the case, but has been exacerbated in recent years due to a growing public awareness of mental illness and of the existence of effective treatment; rising healthcare costs; and the state’s growing substance abuse problem, particularly the brain-damaging use of methamphetamine and resultant psychotic behavior.

Through the use of proven practices and expansion of community based services, the department will increase the effectiveness of services and continue to improve the efficiency of the delivery system. The department’s goal is to ensure access to appropriate care for all Oklahomans and the recovery of all served.

In the mid-1970s, the concept of “deinstitutionalization” prompted states to increase efforts to utilize outpatient services through Community Mental Health Centers. This approach has proven to be an effective means of recovery and a less costly method to provide services as compared to long-term inpatient care in a hospital setting.

Today, over 60,000 individuals receive services from the department each year. Of those, only about 5 percent require hospital care. The vast majority take part in mental health and substance abuse outpatient programs, targeted community based services, prevention efforts and educational initiatives.

In fact, Oklahoma has become a national leader in several areas of community based services including the implementation of programs for assertive community treatment, alternative criminal justice initiatives such as drug and mental health courts, and comprehensive services for children and families.

In many ways, Oklahoma already is “ahead of the curve” in terms of treatment success for people with mental illness or substance abuse problems. With a focus on community-based and proven practices, and emphasis on treatment across the lifespan, from children to the elderly, more Oklahomans with mental illness and substance abuse problems are being served than ever before.

The ODMHSAS was established through the Mental Health Law of 1953, although publicly supported services to Oklahomans with mental illness date back to early statehood. Until the mid-1960s, the primary means to treat mental illness was institutionalization in large state hospitals. On an average day in 1960, nearly 6,400 Oklahomans were in the state’s mental hospitals.

25

Member

Terry Taylor, President 800 N. Research Parkway, Suite 400 Oklahoma City, OK 73103 Phone: (405) 271-2200 Website: www.oklahomahealthcenter.com The mission of the Foundation is to promote innovations in healthcare and science, and to serve as a connector between our member organizations, in order to raise awareness of the Oklahoma Health Center’s profile among business and governmental entities as a key driver of economic development.

The Oklahoma Health Center (OHC) is unique, unlike any other medical center in the United States or even the world. With an annual economic impact of almost $3 billion in the greater Oklahoma City area, the OHC represents the second largest concentration of employees and students in Oklahoma — more than 18,000 —larger than a number of Oklahoma communities.

Chartered in 1965, the Oklahoma Health Center Foundation, Inc. (OHCF) was established to assist the Oklahoma Health Center, and its 21 member entities, in matters of mutual physical, administrative and planning concerns.

This assistance helps drive the OHC’s potential in attracting and developing biomedical and biotechnical industries in Oklahoma. From cutting-edge biotechnology companies to government, medical education, patient care and community support institutions, OHCF serves as the facilitator to 21 world-renowned organizations.

OHCF works closely with many aspects of the campus and its organizations, serving as a liaison between Federal, State, County and City governments by representing the various interests of the campus.

26

OHCF’s Board recently voted to assume management of the emerging OKC Innovation District which encompasses the Health Center across I-235 to Automobile Alley.

OHCF, in the spirit of fostering collaboration, OHCF is hosting symposiums and quarterly Mind-Meld events.

OHCF is a founding member of the 10th Street Medical Business Corridor, a vital and stabilizing anchor to north downtown, which links the OHC campus to other medical facilities in the area, along 10th street.

OHCF is responsible for the implementation of the campus Master Plan, which seeks to establish the Treasures For Tomorrow program began in 2002, and almost $3 million was raised. Projects included public art sculptures at Dean McGee Eye Institute and The Children’s Hospital, and Founders Plaza at Stiles Park featuring the Beacon of Hope. In 2016, the focus was changed to donate monies raised to health-related research projects. Treasures For Tomorrow, $50,000 was awarded to OUHSC and the Harold Hamm Diabetes Center to further the research on this existing project focusing on diabetes.

OHCF is involved in the plans for a modern and comprehensive way-finding signage project.

Since 2000, more than $534 million in construction costs have been completed at the campus. OHCF continues to serve as a facilitator between developing agencies and their surrounding agencies, ensuring the successful and orderly growth of the campus.

OHCF continues to serve the campus interests as a key stakeholder through meetings with the City of Oklahoma City in discussing the proposed MAPS 3 streetcar development and its potential service to the OHC. OHCF continues to represent the interests of the OHC in the successful, revitalization development of downtown Oklahoma City by closely working with the City of Oklahoma City, the Greater OKC Chamber of Commerce and Downtown OKC, Inc.

Member

Terry Cline, Ph.D. Commissioner 1000 N.E. 10th Oklahoma City, OK 73117 Phone: (405)271-4200 Website: www.health.ok.gov A Day in the Life of Public Health…

From the time you get up in the morning till you go to bed at night, public health is involved in your life: • When you got up this morning, you made food choices for breakfast. We provide you messages on healthy food choices.

• You have a yearning for that cigarette you are trying to give up. We work with the Oklahoma Tobacco Helpline to help you quit smoking.

• Hopefully, you brushed your teeth. We work with communities to fluoridate water supplies.

• You got in the car and buckled in your children, put the baby in the car seat, and buckled your own seatbelt. We encourage seat belt use and provide car seats to those who need them.

• You dropped the kids off at school. All should have their mandated immunizations to protect them from childhood diseases. We provide immunizations.

• You go to work where most of your colleagues seem to be sick. We investigate disease outbreaks.

• You go to lunch at a local restaurant. We inspect food service facilities.

• You decide not to go back to work – since everyone’s sick anyway – so you think you’ll get that tattoo you’ve been dreaming about. We license tattoo artists.

• You decide to visit your grandmother to show off your new tattoo. She’s at a local nursing facility. We license nursing homes.

• You pick the kids up from the after-school program.

It’s one that works with the health department to

provide lots of physical activity and healthy snacks.

• You stop off at the grocery store where you see a friend selecting fresh fruits and produce. You know she’s on WIC, the special nutrition program for women, infants and children. We administer the program.

• You start to prepare dinner. You wash your fruits and vegetables to help prevent contamination from E. coli bacteria. The Public Health Laboratory analyzes food specimens during foodborne illness outbreaks.

• Your sister calls and says she has enrolled in the Children First program. This is a special nurse visitation program provided by county health departments to visit first-time mothers in their home and teach them about caring for their new baby.

• After dinner you go for a walk and let the kids ride their bikes. Public health partners with communities to encourage safe sidewalks and bike trails to promote physical activity.

• While outside, you make sure everyone has used insect repellent containing DEET to prevent mosquito bites and tick bites. We investigate cases of West Nile virus caused by mosquito bites, and Rocky Mountain spotted fever, caused by tick bites.

• You put the baby to bed in a crib that meets current federal safety standards and is free of bumper pads so the baby cannot suffocate. You place the baby on its back, the safest position. We provide education on child safety.

• On the 10 o’clock television news, you learn that HIV continues to be of concern in Oklahoma. Public health provides testing for HIV. • Overnight, a tornado hits your community. When you turn on the radio the next morning, you hear messages that your local health department will be providing tetanus shots for those involved in the cleanup.

So indeed, public health is at work every day to keep Oklahomans healthy!

27

Member

Stephen M. Prescott, M. D., President 825 N.E. 13th Street Oklahoma City, OK 73104 Phone: (405)271-7400 Website: www.omrf.org JOBS at OMRF -- https://jobs.omrf.org/applicants/jsp/ shared/frameset/Frameset.jsp?time=1380829938244 What if there was a place solely focused on research?

A place where collaboration could thrive and ideas could grow? Where the stage was set for life-changing discoveries?

There is.

It’s the Oklahoma Medical Research Foundation.

• OMRF scientists hold 700 US and international patents and have developed two FDA-approved drugs.

• The Scientist magazine named OMRF among the “Best Places to Work” for postdocs and in academia in 2011, 2012 and 2013.

• For our work on rheumatoid arthritis and lupus, the National Institutes of Health has designated OMRF as one of only nine Autoimmunity Centers of Excellence in the US. • Our internationally recognized cardiovascular biologists are studying how blood-vessel formation impacts heart disease and breast and colon cancer.

• Researchers at OMRF have identified more than 25 genes associated with lupus and five linked to Sjögren’s syndrome.

28

• Physicians in OMRF’s Multiple Sclerosis Center of Excellence offer the region’s most comprehensive center for researching and treating MS. • OMRF is seeking novel methods of preventing age-related macular degeneration, hearing loss, osteoarthritis and diabetes.

• For 12 consecutive years, OMRF has earned a four-star rating—the highest possible score—from Charity Navigator, America’s largest independent charity evaluator.

• With 18 vertical wind turbines that generate 85,000 kilowatt hours of energy each year, OMRF’s research tower is home to the world’s largest wind farm.

• Our new biorepository holds more than 1 million patient samples in a massive freezer that maintains a constant temperature of -112 degrees Fahrenheit.

• Scientists at OMRF led the largest genetic experiment ever in the field of lupus research, working with 50 scientists in 6 countries to study biological samples gathered from 15,000 patients.

• OMRF has discovered an experimental medication to treat a deadly form of brain cancer. The investigational new drug is currently in clinical trials.

OMRF. Discoveries that make a difference.

Member

Oklahoma School of Science and Mathematics Frank Wang, Ph.D., President The Oklahoma School of Science and Mathematics 1141 North Lincoln Boulevard Oklahoma City, Oklahoma 73104 Phone: (405) 521.6436 Website: www.ossm.edu Only one of a handful of high schools of its kind in the nation, the Oklahoma School of Science and Mathematics is a unique learning institution for Oklahoma students. OSSM is Oklahoma’s public residential high school for juniors and seniors with exceptional interest and abilities in mathematics and science. OSSM operates its two-year residential program in Oklahoma City, Regional Center programs around the state and also serves all Oklahoma schools and students through math contests, research, teacher training and outreach activities.

OSSM was created by the Oklahoma Legislature in 1983 and is funded by the state, with additional private partnership garnered by the OSSM Foundation. The school is governed by a Board of Trustees appointed by legislative leaders and the Governor. Located on a 32-acre site near the state capitol and adjacent to the teaching and scientific research resources of the Oklahoma Health Sciences Center, OSSM is committed to building a strong academic foundation for each student.

The school’s residency program is designed to encourage an atmosphere of informal interaction among peers and foster each student’s highest potential. The availability of laboratories along with evening and weekend programs of interest challenge students and stimulate studies. Since classes began in 1990, students have matriculated from all of Oklahoma’s 77 counties to undertake OSSM’s advanced curriculum taught by a world class, largely Ph.D. faculty, leaping forward in their academic progress.

While in residence at OSSM for their junior and senior years, students receive five and one-half days of academic instruction every week in college-level courses

and participate in physical education and Fine Arts programs. Most science classes feature a two-or-threehour weekly laboratory experience, and many seniors participate in mentorship programs with researchers and other professionals in areas of personal interest.

Students must also receive satisfactory participation reports in both campus and community service of which a total of 120 hours are required for graduation (see more at www.ossm.edu/academics). All OSSM graduates go on to pursue higher education with many earning valuable scholarships and, depending on their receiving school, many begin college with substantial credit hours already completed.

OSSM graduates are continuing to leave indelible marks on Oklahoma. Of the more than 1,500 OSSM graduates thus far, more than a third have pursued engineering and roughly another third are in medicine or bioscience. Based on alumni reports, we estimate more than half of OSSM grads who have completed their higher education have also earned graduate degrees, and a substantial number have served or are serving in the U.S. armed forces.

Some 85% of OSSM alumni are staying in careers in science, math, engineering and technology. More than half are now working or living in Oklahoma and a number have also begun their own businesses. GE Global Research cited OSSM as one of ten critical site selection factors in their decision to build a new research facility in Oklahoma City, and a recent independent analysis found OSSM and its graduates already stimulating more than $40 million each year in economic activity in Oklahoma. OSSM’s impact is growing with every graduating class!

29

Member Charles L. Spicer, Jr., FACHE President and Chief Executive Officer of OU Medical System

Jon Hayes, MHA, CMPE Chief Executive Officer of The Children’s Hospital at OU Medical Center

Kris Wallace

Chief Operating Officer OU Medical Center

OU Medical Center 700 NE 13th St., Oklahoma City, OK 73104 oumedicine.com/oumedicalcenter Follow us on Twitter at @oumedicine Like us on Facebook at facebook.com/oumedicine Follow us on Instagram at instagram.com/oumedicine The Children’s Hospital at OU Medical Center 1200 Children’s Ave. Oklahoma City, OK 73104 oumedicine.com/childrens Like Children’s on Facebook at www.facebook.com/OKChildrens For career information, visit careers.oumedicine.com/now-hiring OU Medical Center is Oklahoma’s largest and most comprehensive hospital dedicated to defining medicine with cuttingedge treatments and working toward solutions for each patient, every time. Our 350-bed hospital provides services not offered elsewhere in the state, including Oklahoma’s only Level I Trauma Center. We provide a full range of heart care services at OU Medicine Cardiovascular Institute, the state’s premier center for treating cardiac and vascular patients. We offer the highest level of care for stroke patients when “time is brain,” and provide unmatched neurology and neurosurgery services ranging from the diagnosis and treatment of epilepsy to the most complex and advanced brain surgeries. We also offer

30

cancer care working alongside Stephenson Cancer Center, including a Gamma Knife Center for treating brain tumors that can’t be treated by conventional methods and a Bone Marrow Transplant Center. With more specialists in more fields than any other hospital in the state, we’re making sure Oklahomans are alive and well.

The Children’s Hospital at OU Medical Center has 314 inpatient beds and is the only freestanding pediatric hospital in Oklahoma solely dedicated to the treatment of children. Our pediatric staff blends years of specialized pediatric training with education, research and technology to treat conditions ranging from cardiothoracic and oncology-related illnesses to neonatal specialty care and pediatric solid-organ transplants. Our 93bed neonatal intensive care unit provides the highest level of neonatal care in Oklahoma. The Children’s Heart Center brings cutting-edge research, treatment and surgery to patients with congenital and acquired heart conditions. We have the state’s largest staff of Child Life specialists to help children and families cope with hospitalization, as well as Oklahoma City’s only 24/7 pediatric emergency room.

Oklahoma is alive and well, and OU Medicine is at its heart.

Member

1200 N. Phillips Ave., Suite 2900 Oklahoma City, OK 73104 Phone: (405) 271-3932 Website: www.oumedicine.com OU Physicians is part of OU Medicine, combining academic knowledge and advanced health care. With more than 560 doctors, OU Physicians is the state’s largest physician group.

The practice encompasses almost every adult and child specialty. Many OU Physicians have expertise in the management of complex conditions that is unavailable anywhere else in the state, region or sometimes even the nation. Some have pioneered surgical procedures or innovations in patient care that are world firsts and many are conducting groundbreaking research to develop new treatments and cures.

More than 175 of our doctors are OU Children’s Physicians.

The majority of them are board-certified in children’s specialties, and many provide pediatric-specific services unavailable elsewhere in the state. Many children with birth defects, critical injuries or serious diseases who can’t be helped elsewhere come to OU Children’s Physicians. Oklahoma doctors and parents rely on OU Children’s Physicians depth of experience, nationally renowned expertise and sensitivity to children’s emotional needs.

In 2009, OU Children’s Physicians opened a new state-ofthe-art facility on the OU Health Sciences Center campus.

A year and a half later, the Children’s Atrium was opened creating a new entrance to not only the children’s physician offices, but the hospital as well. The following year, the final piece of this construction project was completed with the opening of the Samis Education Center, further enhancing the campus’ ability to provide the highest quality education services to faculty, staff and students.

Many OU Physicians see patients through specialty centers like The Peggy and Charles Stephenson Cancer Center and Harold Hamm Diabetes Center.

The Cancer Center building represents the largest public-private biomedical initiative in Oklahoma history.

The 210,000 square-foot facility provides

Brian Lynn Offic Brian Maddy, Chief Executive Officer and Lynn Mitchell, M.D., Chief Medical Officer patient-center care, offering the most advanced cancer detection and treatment technology, the largest and most experienced group of cancer specialists, a wide array of supportive services and an environment that provides a warm and comforting experience for patients and caregivers.

Members of the Cancer Center - including faculty from OU Health Sciences Center, OU Norman, OU Tulsa, Oklahoma State University and the Oklahoma Medical Research Foundation - conduct innovative and nationally-funded cancer research in the basic, clinical and population sciences.

Harold Hamm serves as the focal point for coordinating and expanding numerous avenues of research, patient care, education and prevention that are required to address the diabetes epidemic in a comprehensive manner. The Center offers outreach efforts throughout the state, partnering with communities and other agencies both inside and outside the University of Oklahoma. The Center was established by the University of Oklahoma with the goal of promoting the wellbeing of all people with or at high risk for diabetes in Oklahoma, regardless of ethnic background or financial status.

OU Physicians see patients in their offices at the OU Health Sciences Center and in Edmond, Midwest City and other cities around Oklahoma. When hospitalization is necessary, they often admit patients to OU Medical Center. Many also care for their patients in other hospitals around the metro area. OU Physicians serve as faculty at the University of Oklahoma College of Medicine and train the region’s future physicians.

For more information about OU Medicine, including OU Physicians and OU Children’s Physicians, go to www.oumedicine.com.

OU Physicians faculty and staff are employed by the University of Oklahoma, one of Oklahoma’s largest employers.

The university attracts leading faculty and staff from around the world. To view job opportunities within OU Physicians, go to this site: www.oumedicine.com/ouphysicians/job-opportunities

31

Member

Tom Gray, President & CEO 655 Research Parkway, Suite 500 Oklahoma City, OK 73104 Phone: 405-319-8150 Fax: 405-319-8168 Website: www.phfokc.com Founded in 1985 with the vision of creating a premier medical center in Oklahoma City, the Presbyterian Health Foundation has invested over $118 million in medical education and research in Oklahoma. This investment has led to medical breakthroughs which touch the lives of individuals and families in communities across the state and nation. It has also brought exciting economic opportunities by positioning Oklahoma at the forefront of genetic research and biotechnology.

Proceeds from the 1985 sale of the Presbyterian Hospital were used to create a foundation which would enhance medical research and education in the state of Oklahoma. Trustees of the Presbyterian Hospital continued with the newly formed foundation and believed the potential for excellent health could become the norm, rather than the exception, for all people.

Nearly 30 years later, Trustees of the Foundation continue to share a set of values, expectations, and modes of behavior refined under strong leadership and forged by a long history of success that has made a tremendous impact on the people of Oklahoma.

32

Over the last decade, Presbyterian Health Foundation developed the PHF Research Park which contains 700,000 square feet of wet lab and office space and provides a place for researchers to translate discovery to solutions, putting science to work solving a specific human health need.

Following the 2013 sale of the PHF Research Park to the University of Oklahoma, the Foundation has returned to focusing its efforts on supporting scientific research and medical education at the Oklahoma Health Center Campus.

The purpose of the foundation is to provide resources and to encourage the development of medical education and research programs, conducted primarily in Oklahoma. The Foundation concentrates its support in four areas: • Medical Research • Medical Education • Community Health Programs • Technology Transfer Researchers, mentors, administrators and leaders in biotech companies are all part of a community of people who bring to life the ideas of PHF’s mission. PHF will continue its mission to support excellent biomedical science where discovery may be translated to therapies that save and enhance human life.

Today, the disclosures in good science, evidenced based knowledge, yield brand new widened horizons of human existence.

Member

Susan Adams, President & Chief Executive Officer 1301 NE 14th Street Oklahoma City, OK 73117 Ronald McDonald House and Main Phone: (405) 424-6873 Ronald McDonald House at The Children’s Hospital Phone: (405) 271-3180 Family Room at The Children’s Hospital Phone (405) 271-2215 Website: www.rmhc-okc.org When a child is hospitalized or receiving ongoing medical treatment, we believe the love and support of family is as powerful as the strongest medicine.

Unfortunately for most parents, being with a hospitalized child means eating out of vending machines and sleeping in chairs or bearing the expense of hotel rooms.

That is why Ronald McDonald House Charities® Oklahoma City is here.

Keeping families close . . . when they need it most At 89% of the world’s leading children’s hospitals, families benefit from at least one RMHC Core Program.

The Children’s Hospital is served by the 14-BR Ronald McDonald House which has been located at NE 14th St and Lottie for more than 32 years, as well as the 14-BR Ronald McDonald House located in Garrison Tower at The Children’s Hospital that opened in 2015.

At our Houses, families can have a bedroom of their own with a comfortable bed, a family-style kitchen with home-cooked meals, and laundry facilities for their personal use.

Worried moms and dads can talk to one another, sharing their hopes and fears.

For the child who is sick or injured, having a Ronald McDonald House means that they can rest easier, knowing that mom and dad are nearby.

The Ronald McDonald Family Room®, located on the sixth floor of The Children’s Hospital, opened in 2008

for day-use respite services. Parents can relax and regroup just steps away from their child’s bedside.

The positive, comforting environment of all three facilities allows the families to focus on their children’s healing process. Services are available to any family with a child 21 years of age or younger receiving medical treatment in Oklahoma City area, regardless of their economic status. Ronald McDonald House Charities Oklahoma City relies on donors and the community for support of daily operations. Guest families stay at no cost and are never turned away due to the lack of finances.

The organization offers career opportunities within the charity, at the Houses and Family Room to help with the daily operations. For open positions, please visit http://rmhc-okc.org/about-us/join-our-team/. Interested candidates should submit a resume to careers@ rmhc-okc.org.

Volunteers are the heart of our charity. Individuals or groups can volunteer in either the Houses or the Family Room.

Volunteers can help by performing weekly duties such as cleaning, organizing, repair work, maintaining flowerbeds, managing the front desk or performing office work.

The organization accepts donated food items and supplies from the public to provide a clean and comfortable environment for all of the guests.

Volunteers can donate time through outside fundraisers, at the Houses or Family Room and at annual events such as Walk for Kids and the Red Shoe Gala.

Volunteers can also participate through the Guest Chef program at RMHC-OKC. Individuals, small groups or organizations can prepare and serve a fresh-made meal for guest families. Meals may be prepared in the wellequipped kitchen or arranged from a restaurant or deli.

For more information about Ronald McDonald House Charities Oklahoma City, please visit www.rmhc-okc. org or call (405) 424-6873.

33

Member

Jason R. Sanders, MD Senior Vice President and Provost P.O. Box 26901, LIB 221 Oklahoma City, OK 73126 Phone: (405) 271-3223 Website: www.ouhsc.edu

In education, research and patient care, the University of Oklahoma Health Sciences Center is the state’s premier academic health center and regional leader in meeting the challenges of 21st-century health care.

The most concentrated source of medical expertise in Oklahoma, the OU Health Sciences Center’s new facilities and new technology -- plus an internationally prominent faculty -- place it at the leading edge of the nation’s institutions of medical education.

One of only four comprehensive academic health centers in the nation with seven professional schools, the OU Health Sciences Center serves more than 3,800 students enrolled in more than 70 health professions, graduate and undergraduate programs on the Oklahoma City campus and at the Schusterman Center at the University of Oklahoma-Tulsa. In addition, more than 700 physicians are receiving residency training in Oklahoma City and Tulsa. Research, training grants and contracts, and sponsored program activities at the OU Health Sciences Center totaled more than $120 million

in FY 2013. With a budget of over $870 million, OUHSC employs more than 1,200 full time faculty and 4,000 staff.

More than half of all NIH expenditures in the state of Oklahoma result from OU Health Sciences Center research.

The OU Health Sciences Center serves as the state’s training facility for physicians, biomedical scientists, nurses, dentists, pharmacists and a wide range of allied health and public health professionals.

The OU Health Sciences Center is known for its research programs in cellular and molecular medicine, gene regulation, structural biology, cancer, diabetes, microbiology and immunology, vision, cardiovascular physiology, neuroscience and pharmaceutical sciences.

The center’s growing faculty and facilities offer unparalleled opportunities for students, patient care and the development of the biomedical industry in Oklahoma.

OU Health Sciences Center-developed technology is advancing the economy of Oklahoma. Companies that commercialize technology created by OU Health Sciences Center researchers have been established in Oklahoma City.

OU has become one of the primary centers in the world for genome studies, with the Norman campus contributing to the human genome project and the OUHSC campus providing a number of microbial pathogen genomes. The OU Health Sciences Center ranks second in the world for the number of microbial genomes being sequenced.

34

Two-thirds of all Oklahoma physicians, half of the state’s dentists and a significant percentage of Oklahoma’s other health care professionals earned their degrees from the OU Health Sciences Center. In addition, the seven OU Health Sciences Center colleges are the primary source of continuing education for the state’s health care professionals.

Member

The scientists, scholars and clinicians appointed to the OU Health Sciences Center faculty stand at the leading edge of their profession. They not only train the next generation of health care providers and researchers,

With cancer being one of the leading causes of death in the United States, The Peggy and Charles Stephenson Cancer Center opened in June 2011. This cancer center allows the people of Oklahoma to receive world-class treatment without leaving the state and is staffed with some of the nation’s finest cancer physicians. It offers state-of-the-art technology, unparalleled cancer research programs, and bench-to-bedside care.

many are themselves practicing professionals actively involved in improving the lives and health of Oklahomans.

The clinical practice of the OU College of Medicine is provided through OU Physicians. These physicians represent the largest multi-specialty medical group in the state with more than 500 physicians, offering almost every adult and child specialty. OU Physicians accepts referrals from across the state and region and care for hospital patients at the OU Medical Center. OU Children’s Physicians is an integral part of OU Physicians.

26

The Harold Hamm Diabetes Center is a comprehensive treatment, research, and educational facility dedicated to eliminating and controlling the effects of all types of diabetes. The Diabetes Center is at the forefront in diabetes-related research, and OUHSC physician researchers are specialists in diabetes care and utilize cutting edge research for the best treatment available research.

35

Member

Dean Gandy, Chief Executive Officer University Hospitals Authority & Trust PO Box 26307 Oklahoma City, OK 73126 Phone: 405-271-4962 Website: www.universityhospitalsauthority.com The University Hospitals Authority and Trust are a state agency and a public trust of the state of Oklahoma.

Their mission is to be a catalyst for excellence in medical education, research and health care.

Through the leadership of the University Hospitals Authority and Trust, state and federal resources are maximized to ensure a dependable source of revenue for growth, development and ongoing support for programs aimed at improved health for all Oklahomans.

Since 1998, the Authority and Trust have invested approximately $900 million in buildings, equipment and programs.

The Trust has built or renovated and now manages over 1.6 million square feet of office and clinical space.

Here are a few key projects funded by the University Hospitals Authority and Trust: • Construction of the M. Dewayne Andrews academic office tower for the OU College of Medicine • The Children’s Atrium, which serves as the front door for The Children’s Hospital at OU Medical Center and OU Children’s Physicians Building • •Samis Education Center, a three-story, state-ofthe-art facility designed to accommodate a wide variety of meeting needs.

• OU Children’s Physicians Building, the first freestanding, pediatric multi-specialty, medical office building in the state, featuring 336,000 square feet of medical office space designed with the needs of young patients and their families in mind.

36

• OU Physicians Building, home to more than 130 physicians, with expertise in a wide range of medical specialties.

• Support for the Clinical Skills Testing and Education Center at the OU Health Sciences Center, offering cutting-edge medical simulation equipment and facilities, as well as a robot-assisted surgical training facility • Support for phase two of the Stanton L. Young Biomedical Research Center, a hub of research activity on the OUHSC campus.

• Support for enhancement and expansion of the Dean McGee Eye Institute • Facility enhancement for the OU College of Dentistry, providing important upgrades and technological enhancements

Member

Paula K. Porter, President & CEO 701 NE 13th Street Oklahoma City, OK 73104 Phone: (405)239-2525 Website: www.wovenlifeok.org Did you know that we were founded as the Oklahoma Society for Crippled Children, Inc.? Since 1925, we have provided services in Oklahoma to people of all abilities. Over the years we have adjusted our services to meet the needs of our community and even changed our name a few times. Along with our board

programming, educational programming, therapy services; which include behavioral, speech and occupational therapy, and financial assistance program. With this new change we will refocus to become completely concentrated on the local needs of our community, ensuring every dollar raised goes back into our community to serve Oklahomans.

We are committed to empowering people of all ages and abilities to find hope and independence through compassionate care, education and support.

of directors, we have once again evaluated the needs of our clients, and determined that in order to better meet the needs of Oklahomans it was time to make a change. Effective August 31, 2017, we will change our name to WovenLife, Inc. Although our name is changing, the services we provide within our community will continue. We remain committed to serving the needs of people of all ages and abilities through our inclusive Child Development Program, Adult Day Center, unique intergenerational 37

Associate Member

Mark W. Kelly, President and CEO 3001 N Lincoln Blvd Oklahoma City, OK 73105 For all locations visit: https://www.oecu.org/locations/ Phone: 405.606.6328 Website: www.oecu.org Oklahoma Employees Credit Union (OECU) has been happy to help Oklahomans for over 60 years. In 2003, OECU was granted a community charter which opened membership to anyone who lives, works, worships or attends school in the Oklahoma City Metro Area.

The financial services industry is rich with innovation and OECU is at the forefront offering digital document signing, Apple Pay™, Touch ID™ and apps for Android™ and iPhone®. If you’re looking for top-rated technology from your financial institution then OECU is right for you.

OECU loves to support community efforts around the Oklahoma City Metro. For example, over the last 5 years donations totaling more than $141,000 have been presented to The Children’s Hospital Foundation. OECU also values the importance of keeping your money local and partners with Keep it Local OK, Plaza District and Uptown 23rd on community enhancement initiatives. Don’t be surprised when you find OECU

38

staff passing out goodies from their Treat Trike and volunteering at events around OKC. In 2012, OECU opened a flagship branch at 3001 North Lincoln Boulevard conveniently located 1.5 miles north of the Oklahoma Health Center Campus. OECU offers two ATMs located on campus. You will find our ATMs inside the OU Medical Center and at the Presbyterian Professional Building. OECU members also enjoy free access to over 900 ATMs across Oklahoma.

Currently, OECU has almost half a billion dollars in assets, employs 125 people and offers branch access at over 91 locations across Oklahoma and over 5,000 locations nationwide. OECU serves over 40,000 people who enjoy benefits such as low or no fees on services, higher rates on deposits, and low rates on home or auto loans.

To keep your money local and join a community that puts people first, not profits visit www.oecu.org or call 405.606.6328 today.

Associate Member

39

Hamm Award...

lutely unique in identifying the contributions of almost every organ in the body to the pathophysiology of Type 2 diabetes.”

sents a unique private/public partnership using philanthropic dollars as a catalyst for desperately needed medical advances, which is especially beneficial in the current environment marked by declining federal funding for medical research.

Harold Hamm Diabetes Center will host a reception honoring DeFronzo, the Prize jurors and previous Prize laureates on June 10, 2017, at the American Diabetes Association 77th Scientific Sessions in San Diego. The Hamm Prize will officially be conferred upon DeFronzo Oct. 16, 2017, in Oklahoma City by Hamm and Boren at the 2017 Connect+Cure Gala benefitting Harold Hamm Diabetes Center.

(continued from page 13)

“I am grateful to Harold Hamm for establishing this important prize and for the leadership and tenacity he has demonstrated by taking action to address the diabetes health crisis,” said OU President David L. Boren. “The CDC has said that at current rates, one in three people in America will develop Type 2 diabetes. This prize is another example of the forward momentum of Harold Hamm Diabetes Center’s efforts to slow growing statistics like these. Dr. DeFronzo’s contributions to science directly benefit millions of Americans receiving treatment for diabetes.”

In Oklahoma, two in three adults are obese or overweight and thus at severe risk for developing Type 2 diabetes. Half of those who already have Type 2 diabetes remain undiagnosed. The disease costs the state of Oklahoma more than $4.3 billion per year. In just 10 years, that number is expected to climb to $6.3 billion per year.

DeFronzo was selected by an international jury of leading diabetes scientists during deliberations held in February at Harold Hamm Diabetes Center in Oklahoma City. He was nominated by jurors Dr. Vivian Fonseca of Tulane University and Dr. Aaron Vinik of the Strelitz Diabetes Center at Eastern Virginia Medical School.

“To my mind very few people in the world have done as much for so many different aspects of diabetes, research, clinical care and teaching,” Fonseca said.

“DeFronzo has to be one of the most singular outstanding stars in the diabetes world,” Vinik said. “He is abso-

Southern Living...

(continued from page 12)

tinued relationship with RMHC gives all of us at Dillard’s an enormous sense of pride. We look forward to another successful fundraiser this year and are honored to support the Ronald McDonald Houses in our communities,” said Denise Mahaffy, senior vice president of Dillard’s.

Previous conferrals of the Hamm Prize were in 2013 and 2015, and the next will occur in 2019. To learn more about the Hamm Prize, please visit www.HaroldHammPrize.org.

Moleculera...

(continued from page 7) president for economic development. “But, when the university has the right partner, it can be one of the most effective ways to transfer innovation from the lab to the marketplace. Dr. Shimasaki has done a great job leading the Moleculera team to commercialize this technology and help the university fulfill its mission to create positive impact from research.”

Commercialization of research is one of the aims of an academic medical center like OUHSC, Tomasek said. In 1998, Oklahoma State Questions 680 and 681 passed, allowing university research to be transformed into start-up companies. Cunningham’s research and Moleculera’s launch is one of several success stories for the university.

“Our mission at OUHSC is not only to conduct groundbreaking research, but to take those findings out of the laboratory and into the commercial realm, where they can begin helping patients,” Tomasek said. “It requires a team of people to make this happen, and the patent award is a significant step in Moleculera’s growth as a company.”