May 2016 Innovate E-Magazine

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May 2016

INNOVATE

OMRF researcher makes colitis, colon cancer breakthrough

A publication of the Oklahoma Health Center Foundation


The Oklahoma Health Center

Welcome to our green publication, Innovate. This communication tool is brought to you by the Oklahoma Health Center Foundation to promote the happenings at the Oklahoma Health Center and bring you the latest information about our member organizations. Since 2000, more than $534 million in construction costs has been invested on the campus. In 2016, the OHC employee and OUHSC student count is approximately 18,000 making it one of the largest employers in Oklahoma. The Oklahoma Health Center is the premier address for research, patient care, education, technology and community health support. Located conveniently in the heart of Oklahoma City, this remarkable 325-acre complex unites 20 medical-related organizations ranging from cutting-edge biotechnology companies to government, education, patient care and community support institutions. As the second largest concentration of employees in Oklahoma, this health care consortium touts a $3 billion capital infrastucture that is continually growing to meet the needs and demands of the people. A recent study determined the Oklahoma Health Center has a more than $3 billion annual economic impact on the community.

800 N. Research Parkway, Suite 400 Oklahoma City, OK 73104 Phone: (405) 271-2200 Website: www.oklahomahealthcenter.com Follow Us on Facebook and Twitter @okhealthcenter

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INSIDE OMRF researcher makes colitis, colon cancer breakthrough

4-5 6-7

Maternal-Fetal Medicine Chief Announced

Osteoporosis

9 Oklahoma Health Center: 50 Years Documentary

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Oklahoma Health Center Campus Map

OHCF Members

10-11 14-38

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OMRF researcher makes colitis, colon cancer breakthrough

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Ground Breaking Research

An Oklahoma Medical Research Foundation scientist has discovered that certain sugars produced by the body play an important role in the development of colitis and, ultimately, colon cancer. The new finding could potentially lead to therapies for ulcerative colitis, Crohn’s disease and colon cancer.

“For studying colitis and colon cancer, the experimental models have been artificial until now,” he said. “By deleting these type of sugar structures, the mice are now forming spontaneous colitis and colitis-associated colon cancer, which is exactly how the disease would occur in humans.”

At OMRF, Lijun Xia, M.D., Ph.D., has spent two decades studying O-glycans, a form of sugar that the body produces and that comprises nearly 80 percent of a thick mucous layer inside the colon and the gastrointestinal tract.

Xia’s lab is now working on the development of therapies to repair the injured mucous layer and repair the sugars to treat colitis and prevent tumor development.

For the current research project, Xia and his lab genetically modified mice so that their bodies wouldn’t produce these sugars. The scientists found that the mucous layer vanished and the mice developed colitis, an inflammatory condition in the large intestine. In addition to colitis, these mice also developed a form of colon cancer (known as colitis-associated cancer) as they aged. “Colorectal cancers pose a significant healthcare problem and are the third most common cancers for both men and women in the U.S.,” said Xia. “But in order to solve this problem, we first have to know the cause. In this case, we think we have found a key to this.” According to Xia, this discovery is important for two reasons. “First, these findings tell us that this mucus made up of O-glycan sugars is essential for preventing the development of colitis and colon cancer,” said Xia, who holds the Merrick Foundation Chair in Biomedical Research at OMRF. “When we deleted the sugar, colitis developed. That makes it essential in prevention.” Second, said Xia, he and his team now have created an effective model to help researchers understand colorectal disease and to develop and test therapies.

“Once you have a tumor, it can often be too late,” said Xia. “Our discovery indicates that if we prevent or control colitis, we’ll likely prevent that tumor from ever forming. That’s significant.” Xia’s disease-relevant findings again illustrate the importance of ‘basic’ research, said OMRF Vice President of Research Paul Kincade, Ph.D. “Researchers had to first understand how the protective mucous layer is put together before they could learn how that results in disease. Xia and his team are acknowledged experts in this field and uniquely positioned to make these discoveries.” Xia has published these new findings in separate papers in a pair of scientific journals, Gastroenterology (May 3 issue) and Mucosal Immunology (May 4 online). OMRF researchers Jianxin Fu, M.D., Ph.D., and Kirk Bergstrom, Ph.D., also contributed significantly to this work. This research was funded by grant R01 DK085691 from the National Institutes of Health, as well as by the Oklahoma Center for Adult Stem Cell Research, the University of Oklahoma’s Stephenson Cancer Center, and a Research Fellows Award from the Crohn’s and Colitis Foundation of America.

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Community Service

Free Oklahoma City Zoo Tickets Offered to Blood Donors This Summer Blood donors get a free trip to the zoo, just by giving this summer with Oklahoma Blood Institute (OBI). May 16 through August 31, each person who donates at a donor center or blood drive will receive a voucher redeemable for two free admissions to the Oklahoma City Zoo. The zoo covers 119 acres and is home to more than 1,800 animals. T-shirts with the message, “You Otter Give Blood”, will feature the Zoo’s lively otters and celebrate the zoo’s support will be given to all who donate. Since as many as three patients’ lives in area hospitals are saved each time someone gives blood, donors can always feel good. Oklahoma Blood Institute provides every drop of blood needed by patients in 154 medical facilities across the state, thanks to its volunteer donors. All hospitals in the metro-Oklahoma City area rely exclusively on OBI to meet their patients’ needs. “We are very grateful to those who don’t let summer activities interrupt their commitment to giving blood,” said John Armitage, M.D., OBI president and CEO. “There’s no ‘vacation’ for those facing life-threatening conditions that require blood transfusions. We truly appreciate the Oklahoma City Zoo’s support of our mission, understanding the challenge of sustaining the blood supply during summer. Its partnership provides great motivation for people to take time to donate.” Anyone who is healthy and 16 years of age* can usually give blood, and donations can be made every 56 days. Health screenings and Donor Rewards points, redeemable in OBI’s online store, are also provided to donors. Participating donor centers are located in central and north Oklahoma City, Ada, Ardmore, Edmond, Enid, Lawton and Norman. To schedule an appointment to

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give or find a blood drive in your area, call 877-3408777, or visit www.obi.org. * 16 year olds must weigh at least 125 pounds and provide signed parental permission; 17 year olds must weigh at least ;125 pounds, 18+ year olds must weigh at least 110 pounds


Maternal-Fetal Medicine Chief Announced Rodney K. Edwards, M.D., has been named professor and chief of the section of Maternal-Fetal Medicine within the department of Obstetrics and Gynecology at the University of Oklahoma College of Medicine. He has also been named director of Obstetric Services at The Children’s Hospital at OU Medical Center. He is seeing patients in the OU Physicians Prenatal Diagnostic Center. Maternal-Fetal Medicine physicians -- also called perinatologists -- are obstetrician-gynecologists who completed additional training in the diagnosis, treatment and ongoing care of complicated pregnancies. Edwards provides treatment (including delivery) for the full range of high-risk pregnancy diagnoses and performs detailed fetal ultrasound examinations. He has specific experience in performing transabdominal cerclage (for patients with cervical insufficiency) and invasive fetal procedures such as transfusions and shunts. Edwards is board certified in maternal-fetal medicine and obstetrics and gynecology. He completed a fellowship in maternal-fetal medicine at the University of Florida College of Medicine, Gainesville, where he also completed his residency and earned a master of science degree in clinical investigation. He earned his medical degree at the University of Texas Health Science Center, Houston. Edwards is a Fellow of the American College of Obstetricians and Gynecologists and a member of the Society for Maternal-Fetal Medicine, Infectious Diseases Society for Obstetrics and Gynecology and American Institute of Ultrasound in Medicine OU Physicians maternal fetal medicine specialists see patients on the University of Oklahoma Health Sciences Center Campus. For an appointment with an OU Physicians maternal fetal medicine specialist, call (405) 271-5400.

Leadership Spotlight

With more than 660 doctors, OU Physicians is the state’s largest physician group. The practice encompasses almost every adult and child specialty. Many OU Physicians have expertise in the management of complex conditions that is unavailable anywhere else in the state, region or sometimes even the nation. Some have pioneered surgical procedures or innovations in patient care that are world firsts. OU Physicians see patients in their offices at the OU Health Sciences Center in Oklahoma City and at clinics in Edmond, Midwest City and other cities around Oklahoma. When hospitalization is necessary, they often admit patients to OU Medical Center. Many also care for their patients in other hospitals around the metro area. OU Physicians serve as faculty at the University of Oklahoma College of Medicine and train the region’s future physicians.

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Osteoporosis: Bones are more than the skeletal structure that forms the body’s overall shape, providing a framework for skin. Bones protect vital organs, from heart and lungs to brain and spine, to name a few. Osteoporosis is a disease that causes bones to become fragile and brittle. “Porous bone,” as translated from Greek, is caused by depletion of calcium and bone protein, leaving bones weak and vulnerable to breakage. Mary Zoe Baker, M.D., OU Physicians endocrinology and diabetes specialist says osteoporosis is quite serious and all too common. “When bone strength is undermined, bones may break under the slightest stress — a minor fall, or as a result of such mundane actions as bumping into furniture or bending over. Fragile bones may snap with even a cough or sneeze. These are called fragility fractures.” She added that fragility fractures often heal slowly and poorly. Baker explained that healthy bone viewed under a microscope will have a honeycomb–like appearance. In contrast, bones affected by osteoporosis are less dense; the honeycomb spaces are much larger, indicating structural abnormality. This unusually porous structure weakens the bone; like the sponge it resembles, the bone is subject to collapse or compression. Like other living tissues, bone tissue breaks down and new tissue replaces the old. Osteoporosis occurs when tissue replacement can’t keep pace with loss of old bone tissue. In the event of a fall, osteoporosis is particularly dangerous. “But the fact that there are no visible symptoms is another danger,” Baker said. “Thinning bone and lost mass aren’t things you can feel as they happen. In fact, osteoporosis is often called the ‘Silent Thief,’ as the first sign of the disease is often the first fracture.” Women are at higher risk for osteoporosis than men, and the risk increases in post-menopausal women, but the disease is not exclusive to females. Men and women share some of the same risk factors: family history, use of steroid medications, lack of exercise, smoking and drinking too much alcohol and lower sex hormone levels. Proper nutrition during childhood and adolescence is critical for building strong, healthy bones and ultimately, for decreasing osteoporosis risk later in life. 8

Calcium is a mineral that helps build strong bones and teeth. It is required throughout a lifetime, more during childhood growth and development and less in midlife. Children between the ages of 9 and 18 require the most calcium due to rapid growth. During these years, the body is able to make new bone faster than it breaks down the old. Bone mass increases as a result. Maximum bone density occurs around age 30 and begins to decline thereafter. “Much more calcium is required later in life to prevent bone loss,” Baker said. “The body stores close to 99 percent of its calcium in bones and teeth, with the remainder circulating in blood and soft tissues. If diet doesn’t provide adequate calcium, the body will take the calcium it needs from bone tissue. Over time, osteoporosis develops.” Insufficient exercise continues to be cited as a primary risk factor for osteoporosis. The Centers for Disease Control and Prevention and the American College of Sports Medicine recommend 30 minutes of exercise daily, with an emphasis on weight-bearing activities. The simplest weight-bearing exercise is walking. Exercise not only improves cardiovascular health, but also enhances bone health. Other non-weight bearing exercise such as swimming may not provide as much benefit in terms of increased bone mass, but will improve flexibility and may make for fewer falls. Frequent falling heightens the risk for osteoporotic


Staying Healthy

Bones At Risk fractures. Any comprehensive preventive regimen or treatment plan will emphasize increased physical activity. A recent review of research on osteoporosis prevention and treatment confirms the strong evidence that calcium and vitamin D intake are critical in the development and preservation of strong bones. Still, aggressive advertising campaigns highlighting the dangers of osteoporosis have targeted consumers, particularly women, and health care providers. “For some patients, it may be appropriate to incorporate prescription medications into a treatment plan,” said Baker. “But despite some serious side effects, many are convinced that prescription drugs are required in order to prevent further bone loss and reduce the risk of fractures.” The Food and Drug Administration has approved hormones as a means to prevent osteoporosis but they are not approved as a treatment. Estrogens, used alone or in combination with progestin, remain the best option for prevention of osteoporosis in women. However, because of other recently identified risks, estrogens are rarely used as a preventive measure. Baker added, “Fortifying one’s diet with calcium and vitamin D; engaging in regular exercise; working to improve balance and common-sense approaches like removing fall hazards from a home– these are practical and very achievable steps to reduce the likelihood of a fracture.” Medications that cause or contribute to bone loss: • Antacids that contain aluminum • Some anti-seizure medicines, such as Dilantin® or Phenobarbital • Cancer chemotherapeutic drugs • Cyclosporin A and FK506 (Tacrolimus - used after organ transplantation) • Gonadotropin-releasing hormone (GnRH) such as Lupron® and Zoladex® (androgen deprivation therapy) • Heparin • Methotrexate

• Proton pump inhibitors (PPIs) such as Nexium®, Prevacid® and Prilosec® • Selective serotonin reuptake inhibitors (SSRIs) such as Lexapro®, Prozac® and Zoloft® • Steroids (glucocorticoids) such as cortisone and prednisone • Thiazolidinediones such as Actos® and Avandia® • Thyroid hormones in excess Do not discontinue any medications before consulting with your health care provider. Break Free from Osteoporosis is a new awareness campaign promoted through the National Osteoporosis Foundation. Learn more at http://nof.org/ In the U.S. alone, as many as 52 million people have osteoporosis, or osteopenia, a precursor to osteoporosis. One in two women over age 50 will experience a broken bone due to osteoporosis One in four men over age 50 will experience a broken bone due to osteoporosis. The most vulnerable areas for fracture are the wrist, hip and spine. Of those people who break a hip, 25 percent die within a year. One of the best defenses against osteoporosis is diet. Eating the right foods is a way to maximize bone strength and boost bone density at any age: • Milk • Yogurt • Cheese • Sardines • Greens • Soy foods • Salmon • Nuts and seeds • Calcium-fortified food, such as orange juice, some cereals

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Oklahoma Health Center Campus *Member Organizations Oklahoma Health Center Foundation

1. American Red Cross of Central Oklahoma 2. Dean McGee Eye Institute* 3. Department of Veterans Affairs Medical Center 4. Easter Seals Oklahoma* 5. Office of the Chief Medical Examiner 6. Oklahoma Allergy and Asthma Clinic* 7. Oklahoma Blood Institute* 8. Oklahoma City Clinic/Global Health Inc. 9. Oklahoma Medical Research Foundation (OMRF)* 9a. OMRF Research Tower 9b. OMRF Bell Building 9c. OMRF Acree-Woodworth Building 9d. OMRF Massman Building 10. Oklahoma School of Science and Mathematics* 11. Oklahoma Department of Health 12. Oklahoma State Department of Mental Health and Substance Abuse Services* 13. Department of Human Services 14. OU Medical Center* A. Presbyterian Office Building B. OU Medical Center C. Radiation Therapy Center D. The Children’s Hospital E. Oklahoma Transplant Center F. OU Medical Surgery Center 15. OU University Research Park (formerly Presbyterian Health Foundation Research Park) A. Building 800 Biolytx Biosource Charlesson Crisalis Cytovance Biologics Medencentive Oklahoma Health Center Foundation* OUHSC Research Labs Rural Enterprises Inc. Transtimulations Research B. Building 840 ARL* DNA Solutions* i2E, Inc. Labcorp Orthocare Innovations Selexys

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C. Building 655 Advancia Corporation OU Medical Center* Hyalose, LLC InterGenetics, Inc. Oklahoma State Regents for Higher Education OneNet OUHSC Potts Family Foundation Presbyterian Health Foundation* Selexys SIWA Smith & Nephew D. Building 755 Altheus Dermamedics Nova Venture Services, LLC Oklahoma Center for the Advancement of Science and Technology (OCAST) URP Management Offices OUHSC Facilities Management OUHSC Risk Management OUHSC Fire Marshall OU Compliance Office Altheus Haus Sickle Cell Foundation Sylvia Bottomly OU College of Public Health Productive Tech Veterans Affairs New Spin 360 E. Building 825 Camille’s Sidewalk Café and Richey’s Grill URP Shipping/Receiving PHF Video Conference Center-Conference Rooms F. Building 885 Cytovance Biologic Manufacturing G. Building 865 Accele Biopharma Analytical Edge Labs DRIK Labs Miles Associates OUHSC – Comparative Medicine OMRF

16. University of Oklahoma Health Sciences Center* A. Allied Health Practice Center B. Basic Sciences Education Building C. Campus Police Station D. College of Allied Health E. College of Dentistry F. College of Medicine/Biomedical Sciences Building G. College of Nursing H. College of Pharmacy I. College of Public Health J. David L. Boren Student Union K. Don E. Hogg Greenhouse L. G. Rainey Williams Pavilion M. Harold Hamm Diabetes Center N. O’Donoghue Research Building O. Stephenson Cancer Center P. OU Children’s Physicians* Q. Child Study Center R. OU Physicians* Building S. Mark Allen Everett Dermatology Building* T. Family Medicine Center* U. Robert M. Bird Library & Graduate College V. Rogers Building W. Service Center Building X. Stanton L. Young Biomedical Research Center Y. Steam and Chilled Water Plant Z. University Health Club AA. University Village (owned by OUNorman) 17. University Hospitals Authority and Trust* 18. Ronald McDonald House Charities of Oklahoma City* 19. Ronald McDonald Family Room (in The Children’s Hospital) 20. Ronald McDonald House II (in Garrison Tower) 21. Founders Plaza at Stiles Park featuring The Beacon of Hope 22. OK Kids Corral 23. Embassy Suites* Children’s Hospital Foundation* (not currently on campus) 24. Oklahoma Employees Credit Union* (not on campus)


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Oklahoma Health Center Celebrates Fiftieth Year of Founding in Documentary A documentary on the history of the Oklahoma Health Center was produced by the Oklahoma Health Center Foundation and funded by the Treasures For Tomorrow program. The documentary is available for viewing through the Oklahoma Health Center Foundation’s You Tube page - https://www.youtube.com/watch?v=7A9xnJieq_s The documentary starts in 1965 when the area now known as the Oklahoma Health Center was just a few buildings – a medical school and two hospitals. Visionaries including Harvey P. Everest, E.K. Gaylord, Dean A. McGee, Dr. Don O’Donohue and Stanton L. Young organized a trip to Houston to see the Texas Medical Center to see if they could recreate something similar in Oklahoma. The answer was a resounding yes and now the Oklahoma Health Center touts a $3 billion impact on Oklahoma’s economy. More than 18,000 employees and students travel to the Oklahoma Health Center each day. The documentary explores the challenges faced and how those obstacles were overcome leading to what the Oklahoma Health Center is today and a glimpse into its ever-changing future. Those interviewed include University of Oklahoma President David Boren, Vice President and Provost OU Health Sciences Center Dr. Jason Sanders, OU College of Medicine Dean Dr. Dewayne Andrews, and Oklahoma Health Center Foundation President Terry Taylor. The Oklahoma Health Center Foundation is a consortium of 20 private, educational, governmental and nonprofit organizations, located on 325 acres just south of the Capitol complex in Oklahoma City. These organizations represent the areas of patient care, research, technology, education and community support with the common goal of improving health and creating high-tech jobs in Oklahoma and the nation. Visit www.oklahomahealthcenter.com for more information.

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ARL Bio Pharma, Inc.

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Children’s Hospital Foundation

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Dean McGee Eye Institute

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DNA Solutions, Inc.

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Easter Seals Oklahoma

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Oklahoma Allergy & Asthma Clinic

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Oklahoma Blood Institute

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Oklahoma Health Center Foundation

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Oklahoma Center for the Advancement of Science and Technology

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Oklahoma Department of Mental Health & Substance Abuse Services

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Oklahoma Medical Research Foundation

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Oklahoma School of Science & Mathematics

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OU Medical Center

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OU Physicians

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Presbyterian Health Foundation

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Ronald McDonald House Charities® of Oklahoma City

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University Hospitals Authority and Trust

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University of Oklahoma Health Sciences Center: College of Allied Health • College of Dentistry College of Medicine • College of Nursing College of Pharmacy • College of Public Health Graduate College

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Member Organizations

Associate Members Oklahoma Employees Credit Union

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Embassy Suites

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Member

Tom Kupiec, Ph.D., President and CEO 840 Research Parkway Suite 546 Oklahoma City, OK 73104 Phone: (405)271 1144 Website: www.arlok.com Analytical Research Laboratories (ARL) provides analytical and microbiological testing for the pharmaceutical industry. Located at the University Research Park in Oklahoma City, ARL occupies approximately 19,000 square feet of state of the art laboratory and office space and positions itself as a leader among emerging and growing biotechnology companies nationwide. ARL has been serving the clinical and pharmaceutical markets since 1998. ARL offers a comprehensive range of analytical and microbiological services applicable for pharmaceuticals and medical devices. ARL services routinely include assay for pharmaceutical ingredients, stability studies, and full compendial testing. ARL is well equipped with instrumentation, such as High Performance Liquid Chromatography (HPLC), HPLC-Tandem Mass spectrometry (HPLC/MS/MS), High resolution Time of Flight Mass Spectrometry (LC-MS) for accurate molecular weight determination and analysis of proteins/peptides with an upper mass range of 20,000 m/z, Gas Chromatography (GC), GC/MS, high resolution Fourier Transform Infrared (FTIR), Polarimeter, ELISA, Genetic Analyzer, Thermal 14

Cyclers, Luminometer, and Environmental Chambers. ARL has a dedicated team of scientists and e x p e r t s continually delivering research solutions for the pharmaceutical industry and governmental institutions. ARL’s competent personnel with regulatory expertise provide a comprehensive approach to analytical testing, as well as forensic and pharmaceutical consultations. Additional experience includes: pharmacogenomics, biomedical sciences, medical technology, immunohematology and expert witness testimony. ARL is an FDA registered analytical laboratory and DEA licensed. ARL is ISO 17025:2005 accredited as applicable to our scope of accreditation. ISO outlines general requirements for the competence of testing and calibration laboratories. An independent QA/QC department conducts internal audits of the laboratories as a part of a quality management system.


Member

Kathy McCracken, Executive Director 6501 Broadway Extension, Suite 190 Oklahoma City, OK 73116 Phone: (405) 271-2260 Toll Free: 888-229-KIDS Tax ID: #73-1200262 Website: www.chfKids.org Children’s Hospital Foundation is the only nonprofit organization in Oklahoma whose sole focus is the advancement of pediatric research and education while supporting specialized clinical care for Oklahoma’s children. It supports pediatric specialists who treat more than 213,000 patient visits every year, including children from all 77 counties in Oklahoma. Since its inception in 1983, Children’s Hospital Foundation has raised and leveraged matching funds to create more than $100 million for pediatric research, quality specialized clinical care and education programs. Many of these endeavors include collaborative projects with the University of Oklahoma College of Medicine and Children’s Hospital at OU Medical Center in Oklahoma City. Current program and research focus areas include: • Infectious disease • Arthritis • Education • At-risk newborns • Diabetes-Obesity • Digestive health • Cancer • Genetics • Community pediatrics • Surgery & Emergency • Autism-ADHD-Down Syndrome • Lung, kidney and heart disease • Adolescent medicine • Eating disorders • Behavioral medicine • Child abuse and neglect Funding for programs is made possible through the efforts of a dedicated volunteer board and thousands of community volunteers and donors. Through endowments and direct support, Children’s Hospital Foundation is able to recruit and retain nationally and internationally recognized pediatric physician-scientists to direct research, as well as

treat patients and train medical students. All funds raised in Oklahoma stay in Oklahoma to improve the lives of kids here at home. Children’s Hospital Foundation is a proud affiliate of Children’s Miracle Network Hospitals, an international nonprofit organization dedicated to helping sick children by raising funds and awareness for 170 member hospitals throughout North America. Children’s Miracle Network Hospitals organizes and executes thousands of special events and promotions each year through its dedicated corporate sponsors and media partners and keeps 100 percent of its donations in the community where they were raised. Children’s Medical Research Institute and The Children’s Hospital at OU Medical Center are part of the network hospitals. The Foundation is currently recruiting endowed chairs and has naming opportunities available. For more information, contact Children’s Hospital Foundation toll free 888-229KIDS (5437) or (405) 271-2260.

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Member

President and CEO Greg Skuta, M.D. 608 Stanton L. Young Blvd. Oklahoma City, OK 73104-5065 Phone: (405) 271-6060 Website: www.dmei.org Benchmarks of Dean McGee Eye Institute Excellence The Dean McGee Eye Institute is one of the largest and most respected eye institutes in the United States, providing more than 176,000 patient visits per year from all 77 Oklahoma counties and the surrounding region, and serving more than 8,100 surgical patients annually in its state-ofthe-art ambulatory surgery center. Twenty of the Eye Institute’s ophthalmologists are listed among the Best Doctors in America. The University of Oklahoma (OU) College of Medicine’s Department of Ophthalmology, which is housed in the Dean McGee Eye Institute, ranks among the country’s top departments in National Institutes of Health funding and is 12th in the nation in cumulative funding from Research to Prevent Blindness. The Dean McGee Eye Institute’s residency program (in affiliation with the OU College of Medicine) attracts top medical students from throughout the nation. Resident surgical education has consistently ranked above the 90th percentile nationally. Since 2000, the first-time pass rates on the American Board of Ophthalmology’s written and oral examinations are 100% and 98% respectively with an average score on the written examination at the 80th percentile. The Eye Institute’s Director of Vision Research is a Past President of the International Society for Eye Research, Past Vice President of the Association for Research in Vision and Ophthalmology (ARVO) and a recipient of ARVO’s prestigious

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Proctor Medal; two members of the faculty are recent or current directors of the American Board of Ophthalmology; three serve or have recently served on the Board of Trustees of the American Academy of Ophthalmology (AAO); one will be President-Elect of the AAO in 2016; another has recently served as Vice Chair of the Residency Review Committee in Ophthalmology for the Accreditation Council for Graduate Medical Education; and one is the Immediate Past President of the AAO and a Past President of the American Glaucoma Society. The Dean McGee Eye Institute provides more than $1 million of care to needy Oklahomans each year.


Member

Thomas C. Kupiec, Ph.D., CEO and President 840 Research Parkway, Ste. 551, Oklahoma City, Oklahoma 73104 Toll Free: (866) 362-9778 Phone: (405) 271-6033 Website: www.dnasolutionsusa.com DNA Solutions, Inc. is a genetic testing laboratory providing highly discerning services including: relationship and forensic testing in humans and animals. Located at the University Research Park in Oklahoma City, DNA Solutions provides unique laboratory solutions to our customers including custom genetic research studies and forensic testing. DNA Solutions is accredited to the highest standard, ISO 17025. ISO/IEC 17025:2005 sets the international laboratory standard for testing laboratories. In addition, DNA Solutions is a CLIA registered laboratory and has its New York State Department of Health Laboratory Permit. DNA Solutions is also accredited by the American Association of Blood Banks (AABB) for relationship testing. AABB accreditation is granted only to laboratories that achieve high quality performance for relationship testing which follows strict quality guidelines that cover all aspects of parentage testing from initial specimen collection to the issuance of the final results.

The company provides research and development expertise in the area of single nucleotide polymorphism (SNP) detection, DNA sequencing for forensics and human and animal genotyping, bacterial / fungal identification, biological patent infringement and ancestry testing. DNA Solutions maintains the deer registry for North American white-tailed deer and mule deer breeders as well as providing genotyping services to wildlife enforcement agencies. One significant distinguishing characteristic of DNA Solutions is the personal client services our company provides. DNA Solutions prides itself in providing high touch customer service to all of our clients. Our highly skilled and knowledgeable personnel are accessible to our clients for questions and explanations regarding results provided to our clients. DNA Solutions provides services worldwide and services are legally defendable and meet or exceed the applicable standards for genetic relationship testing. For over 14 years, the innovative scientists at DNA Solutions have been helping people discover the answers contained within the strands of DNA.

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Member

Paula K. Porter, President & CEO 701 NE 13th Street Oklahoma City, OK 73104 Phone: (405)239-2525 Website: www.eastersealsok.org

More than 56 million Americans have a disability, which accounts for approximately 19 percent of the population. Easter Seals Oklahoma is the leading nonprofit provider of services for individuals with disabilities and is trying to bridge the gap for the increasing number of Oklahomans needing services.

For more than 90 years, we have been offering help and hope to children and adults with disabilities and to the families who love them. Through therapy, training, education and support services, Easter Seals Oklahoma creates life-changing solutions so that people with disabilities can live, learn, work and play. Our adult day health center provides special care for adults who are unable to care for themselves for extended periods of time and enables them to maintain

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or improve their ability to remain independent. The program provides various activities to stimulate minds, promote social interaction and keep everyone moving. Our early learning and inclusion academy includes an onsite learning program for children with disabilities as well as typical children, and a peer integration program to increase early intervention. Consultation services are available for parents and teachers that need additional support and training on developmental disabilities. Easter Seals Oklahoma also provides direct financial assistance for children needing therapy, as well as a variety of rehabilitative equipment that is necessary for a child’s development. Medical rehabilitation is available onsite for behavioral, occupational and speech therapies. It is our mission at Easter Seals Oklahoma to enhance the quality of life for children and adults with disabilities so they may live with equality, dignity and independence. Thanks to the support of the community, we are able to fulfill our mission.


Member

Serving Oklahoma and the southwest since 1925, the Oklahoma Allergy & Asthma Clinic is one of the oldest and largest medical practices in the United States dedicated solely to the treatment of allergy, asthma and immunology. The Oklahoma Allergy & Asthma Clinic has nine physicians on its medical staff; board certified by the American Board of Allergy & Immunology and are on the teaching faculty at the University of Oklahoma College of Medicine. The Oklahoma Allergy & Asthma Clinic is one of only a few allergy groups in the United States with a full-time Nurse Practitioner who holds a Doctorate and is a pulmonary disease management coordinator consulting with individual patients about breathing techniques and asthma education. Also on staff is a full-time, registered, licensed nurse practitioner. Almost one-fourth of The Oklahoma Allergy & Asthma Clinic’s patients are referred from outside Oklahoma City and travel many miles for the sophisticated, high-level allergy and asthma care and to participate in the numerous research studies. The Oklahoma Allergy & Asthma Clinic has a Burkard pollen and mold collection instrument on the roof of its main location and provides the daily counts to the media and the counts are also posted on the website and on social media. The Oklahoma Allergy & Asthma Clinic has its central clinic

Shahan Stutes, M.D. 750 N. E. 13th Street Oklahoma City, OK 73104-5010 Phone: (405) 235-0040 Website: www.oklahomaallergy.com Facebook oklahomaallergyandasthmaclinic Twitter @okallergyasthma location on the Oklahoma Health Center campus. Three full-service satellite clinics are located in Edmond, Norman, Midwest City and Northwest Oklahoma City, adjacent to Mercy Hospital. A new building is under construction in Norman. How is an allergist different than a regular physician? An allergist is a doctor who is an expert in the diagnosis and treatment of allergic diseases and conditions. Those conditions include asthma and frequent coughing; hay fever; sinus infections; eye allergies; reactions to food, insect stings and drugs; and immune system problems that might cause frequent infections. You should see an allergist if you have any of these conditions. More than 50 million people in the United States have these allergic diseases. Although symptoms may not always be severe, allergies and asthma are serious and should be treated that way. Many people with these diseases simply don’t realize how much better they can feel with proper treatment. An allergist is trained to find the source of symptoms, treat it and help patients feel healthy. After earning a medical degree, the doctor must complete a three-year residencytraining program in either internal medicine or pediatrics. Then, an allergist completes two or three more years of study in the field of asthma, allergy and immunology.

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Member

ity to recruit marrow registrants from ethnically and agediverse populations.

John Armitage, M.D., President, CEO 1001 N. Lincoln Blvd. Oklahoma City, OK 73104 Phone: (405) 278-3100 Website: www.obi.org Oklahoma Blood Institute (OBI) is the ninth largest, nonprofit blood center in America. Every drop of blood needed by patients in more than 140 medical facilities in Oklahoma is provided by donors with OBI. This includes exclusive service for every hospital in the metro-OKC area. An average of 700 donors a day is required to meet these needs. Volunteer blood donors give more than a 287,000 units of blood annually to provide a safe and adequate blood supply. Blood donors with Oklahoma Blood Institute know they are, literally, saving the lives of their friends, family and coworkers, some who may have no idea they will need blood in an urgent situation. One blood donation can save as many as three peoples’ lives. OBI is responsible for recruiting blood donors, collecting, processing and testing blood components and transporting it to hospitals across our state. Random inspections by the Food & Drug Administration (FDA) confirm the quality of our operations at every donation site. OBI’s perfect record through 36 straight inspections validates our quality exceeding regulatory requirements. OBI employs 642 Oklahomans and works with 1,200 volunteers and 2,600 blood drive coordinators. Its donor centers are located in Ada, Ardmore, Edmond, Enid, Lawton, Norman, central Oklahoma City (Oklahoma Health Center), north Oklahoma City and Tulsa. Numerous mobile blood drives are conducted in conjunction with businesses, schools and civic groups each week across the state. Oklahoma Blood Institute is the state’s only affiliate of Be The Match®, the national marrow donor program. For more than 12,000 Americans each year, a marrow or stem cell transplant is the only hope for a cure of a life-threatening blood cancer or other blood disorder. For the past three years, OBI has ranked in the top performance tier, due to our abil-

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Oklahoma’s first and only umbilical cord blood bank is in the final phases of FDA accreditation at OBI. It is one of only 24 accredited centers worldwide. Expectant mothers of underserved ethnic descent families now have an opportunity to donate cord blood. There is no charge to the parents, and the donation process is simple and painless. During a blessed time in their own lives, this cord blood center enables Oklahoma families to potentially bring life-saving joy to someone else’s. OBI is a vital link in cell therapy, procuring healthy stem cells for transplants from adult marrow and umbilical cord donations. The future holds great promise as we expand research and treatments partnerships within the healthcare biosciences industry. Cell therapies and regenerative medicine applications are predicted to revolutionize care for the most life-threatening diseases. We are uniquely positioned as a ready-made ‘cell bank’ with hundreds of thousands of combinations of genetic characteristics among our blood donors. These giving people may be offered the opportunity to further make a difference in the lives of others as part of medical research. Oklahoma Blood Institute can accelerate this revolutionary research cost effectively, so that today’s vision more rapidly becomes the reality of life-enhancing, routine medical treatments.


Member

Terry Taylor, President 800 N. Research Parkway, Suite 400 Oklahoma City, OK 73103 Phone: (405) 271-2200 Website: www.oklahomahealthcenter.com The mission of the Foundation is to promote innovations in healthcare and science, and to serve as a connector between our member organizations, in order to raise awareness of the Oklahoma Health Center’s profile among business and governmental entities as a key driver of economic development. The Oklahoma Health Center (OHC) is unique, unlike any other medical center in the United States or even the world. With an annual economic impact of almost $3 billion in the greater Oklahoma City area, the OHC represents the second largest concentration of employees and students in Oklahoma — more than 17,000 —larger than a number of Oklahoma communities. Chartered in 1965, the Oklahoma Health Center Foundation, Inc. (OHCF) was established to assist the Oklahoma Health Center, and its 20 member entities, in matters of mutual physical, administrative and planning concerns. This assistance helps drive the OHC’s potential in attracting and developing biomedical and biotechnical industries in Oklahoma. From cutting-edge biotechnology companies to government, medical education, patient care and community support institutions, OHCF serves as the facilitator to 23 world-renowned organizations.

OHCF works closely with many aspects of the campus and its organizations, serving as a liaison between Federal, State, County and City governments by representing the various interests of the campus. OHCF is a founding member of the 10th Street Medical Business Corridor, a vital and stabilizing anchor to north downtown, which links the OHC campus to other medical facilities in the area, along 10th street. OHCF is responsible for the implementation of the campus Master Plan, which seeks to establish the Oklahoma Health Center as the primary destination for health care and education and the continued building of a campus that will sustain OHC’s status as a true major economic engine for the region. OHCF initiated campus beautification projects with the creation of parks and adding public art projects throughout the campus. The Treasures For Tomorrow program began in 2002, and almost $3 million has been raised. Projects include public art sculptures at Dean McGee Eye Institute and The Children’s Hospital, and Founders Plaza at Stiles Park featuring the Beacon of Hope. OHCF is involved in the plans for a modern and comprehensive way-finding signage project. Since 2000, more than $534 million in construction costs have been completed at the campus. OHCF continues to serve as a facilitator between developing agencies and their surrounding agencies, ensuring the successful and orderly growth of the campus. OHCF continues to serve the campus interests as a key stakeholder through meetings with the City of Oklahoma City in discussing the proposed MAPS 3 streetcar development and its potential service to the OHC. OHCF continues to represent the interests of the OHC in the successful, revitalization development of downtown Oklahoma City by closely working with the City of Oklahoma City, the Greater OKC Chamber of Commerce and Downtown OKC, Inc. 21


Member

Michael Carolina, CEO 755 Research Parkway, Suite 110 Oklahoma City, OK 73104-3612 Local: (405)319-8400 Toll Free: 866-265-2215 In Tulsa: 618 East Third Street, Suite 5 Tulsa, OK 74120 918-576-7650 Website: www.ocast.ok.gov Facebook: www.facebook.com/ocast.ok.gov Twitter: www.twitter.com/ocast The Oklahoma Center for the Advancement of Science and Technology (OCAST) was established in 1987 as the state’s agency for technology-based economic development. OCAST’s mandate is to “expand and diversify Oklahoma’s economy and provide new and higher quality jobs for Oklahomans” by encouraging “. . . the development of new products, new processes and

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whole new industries in Oklahoma.” (O.S. 74, Sections 5060.1a and 5060.2A) MISSION To foster innovation in existing and developing businesses • by supporting basic and applied research • by facilitating technology transfer between research laboratories and businesses • by providing seed capital for innovative firms in the development of new products or services • by helping Oklahoma’s small and medium-sized manufacturing firms become more competitive through increased productivity and modernization (O.S. 74, Section 5060.3) VISION OCAST funds cutting-edge science and technology through processes that are recognized nationally and internationally for demonstrating excellence, objectivity and economic impact. OCAST’s vision is continued growth and vitality of its basic premise of facilitating collaborations between state government, universities, start-up companies and established large-scale firms to develop an entrepreneurial environment which supports technologybased economic development. OCAST’s strategy includes technologies such as biosciences, information technology, sensors and electronics, advanced materials, energy and alternative fuel sources. Achieving this vision will result in continued growth of advanced technology companies in the state thereby increasing Oklahoma’s global competitiveness, per capita income and quality of life.


Member

Terri White ODMHSAS Commissioner 1200 N.E. 13th Street Oklahoma City, OK 73117 Phone: (405) 522-3878 Website: www.odmhsas.org

The Oklahoma Department of Mental Health and Substance Abuse Services is responsible for providing services to Oklahomans who are affected by mental illness and substance abuse. In fiscal year 2008, the department provided services to 64,465 individuals – an increase of nearly 3,600 individuals over the previous year. The demand for public mental health services exceeds the capacity of the current treatment system. This has always been the case, but has been exacerbated in recent years due to a growing public awareness of mental illness and of the existence of effective treatment; rising healthcare costs; and the state’s growing substance abuse problem, particularly the brain-damaging use of methamphetamine and resultant psychotic behavior. Through the use of proven practices and expansion of community based services, the department will increase the effectiveness of services and continue to improve the efficiency of the delivery system. The department’s goal is to ensure access to appropriate care for all Oklahomans and the recovery of all served.

In the mid-1970s, the concept of “deinstitutionalization” prompted states to increase efforts to utilize outpatient services through Community Mental Health Centers. This approach has proven to be an effective means of recovery and a less costly method to provide services as compared to long-term inpatient care in a hospital setting. Today, over 60,000 individuals receive services from the department each year. Of those, only about 5 percent require hospital care. The vast majority take part in mental health and substance abuse outpatient programs, targeted community based services, prevention efforts and educational initiatives. In fact, Oklahoma has become a national leader in several areas of community based services including the implementation of programs for assertive community treatment, alternative criminal justice initiatives such as drug and mental health courts, and comprehensive services for children and families. In many ways, Oklahoma already is “ahead of the curve” in terms of treatment success for people with mental illness or substance abuse problems. With a focus on community-based and proven practices, and emphasis on treatment across the lifespan, from children to the elderly, more Oklahomans with mental illness and substance abuse problems are being served than ever before.

The ODMHSAS was established through the Mental Health Law of 1953, although publicly supported services to Oklahomans with mental illness date back to early statehood. Until the mid-1960s, the primary means to treat mental illness was institutionalization in large state hospitals. On an average day in 1960, nearly 6,400 Oklahomans were in the state’s mental hospitals.

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Member

Stephen M. Prescott, M. D., President 825 N.E. 13th Street Oklahoma City, OK 73104 Phone: (405)271-7400 Website: www.omrf.org JOBS at OMRF -- https://jobs.omrf.org/applicants/jsp/ shared/frameset/Frameset.jsp?time=1380829938244 What if there was a place solely focused on research? A place where collaboration could thrive and ideas could grow? Where the stage was set for life-changing discoveries? There is.

It’s the Oklahoma Medical Research Foundation. • OMRF scientists hold 700 US and international patents and have developed two FDA-approved drugs. • The Scientist magazine named OMRF among the “Best Places to Work” for postdocs and in academia in 2011, 2012 and 2013. • For our work on rheumatoid arthritis and lupus, the National Institutes of Health has designated OMRF as one of only nine Autoimmunity Centers of Excellence in the US. • Our internationally recognized cardiovascular biologists are studying how blood-vessel formation impacts heart disease and breast and colon cancer. • Researchers at OMRF have identified more than 25 genes associated with lupus and five linked to Sjögren’s syndrome. 24

• Physicians in OMRF’s Multiple Sclerosis Center of Excellence offer the region’s most comprehensive center for researching and treating MS. • OMRF is seeking novel methods of preventing age-related macular degeneration, hearing loss, osteoarthritis and diabetes. • For 12 consecutive years, OMRF has earned a four-star rating—the highest possible score—from Charity Navigator, America’s largest independent charity evaluator. • With 18 vertical wind turbines that generate 85,000 kilowatt hours of energy each year, OMRF’s research tower is home to the world’s largest wind farm. • Our new biorepository holds more than 1 million patient samples in a massive freezer that maintains a constant temperature of -112 degrees Fahrenheit. • Scientists at OMRF led the largest genetic experiment ever in the field of lupus research, working with 50 scientists in 6 countries to study biological samples gathered from 15,000 patients. • OMRF has discovered an experimental medication to treat a deadly form of brain cancer. The investigational new drug is currently in clinical trials. OMRF. Discoveries that make a difference.


Member

Oklahoma School of Science and Mathematics Frank Wang, Ph.D., President The Oklahoma School of Science and Mathematics 1141 North Lincoln Boulevard Oklahoma City, Oklahoma 73104 Phone: (405) 521.6436 Website: www.ossm.edu Only one of a handful of high schools of its kind in the nation, the Oklahoma School of Science and Mathematics is a unique learning institution for Oklahoma students. OSSM is Oklahoma’s public, tuition-free, residential high school for juniors and seniors with exceptional abilities in mathematics and science. The school’s residency program is designed to encourage an atmosphere of informal interaction among peers and foster each student’s highest potential. The availability of laboratories, along with evening and weekend programs of interest, challenge students and stimulate studies. OSSM was created by the Oklahoma Legislature in 1983 and is funded by the state. The school is governed by a Board of Trustees, which is appointed by legislative leaders and the governor. Although the history of the school is grand, the wonderfully gifted students are at the heart of OSSM. Since its inception 22 years ago, students have matriculated from all of Oklahoma’s 77 counties.

The campus is located on a 32-acre site near the state capitol and adjacent to the teaching and scientific research resources of the Oklahoma Health Center. In the summer of 2000, the school completed a $25 million campus building program. The classrooms and offices of the historic Lincoln School were restored through a unique partnership with Oklahoma patrons, organizations, businesses and government entities and is now called the Manning Academic Center. Students live in the school’s Dan Little Residence Hall that accommodates 144 students and faculty families. OSSM also has a gymnasium, Bernice Shedrick Library and Samson Science and Discovery Center, which houses physics and chemistry laboratories. The dormitory has expanded to allow the school to house 100+plus additional students per year should funding become available from the state to ensure the school’s future and keep the dream alive for Oklahoma’s best and brightest students. OSSM is committed to building a strong academic foundation for each student. While in residence at OSSM, students are required to complete successfully four and one-half units of science, two units of mathematics, one-half unit of computer science, two units of English, two units of history, two units of a foreign language, one unit of fine arts, and two units of physical education. Each science class features a two-or-three-hour weekly laboratory experience. Students receive five and onehalf days of academic instruction every week. Students must also receive satisfactory participation reports in both campus and community service and a total of 120 hours are required for graduation. The graduates of OSSM have already left their indelible marks on Oklahoma. Of the more than 1,300 OSSM graduates since the first class, 300 are engineers and nearly 100 are medical doctors. More than 50 have earned Ph.D.s and 75 have served in the U.S. armed forces. Eighty-five percent of these graduates have careers in science, math, engineering and technology. More than half now work or live in the state and 10 graduates have begun their own businesses in Oklahoma.

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Member

Charles L. Spicer, Jr., FACHE President and Chief Executive Officer of OU Medical System

Jon Hayes, MHA, CMPE Chief Executive Officer of The Children’s Hospital at OU Medical Center

OU Medical Center

700 NE 13th, Oklahoma City, OK 73104 www.oumedicine.com/oumedicalcenter Follow us on Twitter at @oumedicine Like us on Facebook at www.facebook.com/oumedicine

The Children’s Hospital at OU Medical Center 1200 N Children’s Ave. (formerly Phillips Ave.), Oklahoma City, OK 73104 www.oumedicine.com/childrens Like Children’s on Facebook at www.facebook.com/OKChildrens For career information, visit www.oumedicine.com/careers OU MEDICAL CENTER—Oklahoma City’s largest and most comprehensive hospital—is the major referral center in central and western Oklahoma for adults and children. We provide a full range of hospital services for every patient, from the smallest neonate to the most critically ill senior. We’ve been in the community for more than 100 years, and envision the next century to be as productive as the first as we grow with our city and community. With more specialists in more fields than any other hospital in the state, we’re making sure Oklahomans are alive and well. Our adult services boast an award-winning tradition of applying innovative treatments to the care of patients in a full range of specialties, including the state’s only Level One Trauma Center and one of the first certified comprehensive stroke centers in the country. OU Medical Center is recognized for its excellence in neurology and neurosurgery, sleep disorders, orthopedics, cancer treatment, critical care and many other areas. Our patients have the advantage of being cared for by some of the premier experts in their field of medicine. Our staff

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works as a team, leading health care and taking what we do to another level of medicine. The Children’s Hospital at OU Medical Center is Oklahoma’s only comprehensive, freestanding pediatric medical center where pediatricians, pediatric specialists and pediatric sub-specialists have been caring for Oklahoma’s children for nearly 90 years. Children’s is home to Oklahoma’s only pediatric emergency department, and has the state’s largest staff of Child Life specialists who help promote development and minimize the stress of hospitalization. For expectant families we offer care in our Women’s & Newborn Center at Children’s Hospital. From the easiest of pregnancies to the most complicated, our staff is experienced in caring for mothers and babies. If a baby needs extra care, she is an elevator ride away from the highest level Neonatal Intensive Care Unit in the state. The Children’s Hospital provides medical care found nowhere else, and excels in specialties like cancer, orthopedics, urology, epilepsy and heart disease. Our staff and affiliated physicians train tomorrow’s health care professionals, conducting innovative medical research and providing compassionate, quality patient care. Oklahoma City is alive and well, and OU Medicine is at its heart.


Member

1200 N. Phillips Ave., Suite 2900 Oklahoma City, OK 73104 Phone: (405) 271-3932 Website: www.oumedicine.com OU Physicians is part of OU Medicine, combining academic knowledge and advanced health care. With more than 560 doctors, OU Physicians is the state’s largest physician group. The practice encompasses almost every adult and child specialty. Many OU Physicians have expertise in the management of complex conditions that is unavailable anywhere else in the state, region or sometimes even the nation. Some have pioneered surgical procedures or innovations in patient care that are world firsts and many are conducting groundbreaking research to develop new treatments and cures. More than 175 of our doctors are OU Children’s Physicians. The majority of them are board-certified in children’s specialties, and many provide pediatric-specific services unavailable elsewhere in the state. Many children with birth defects, critical injuries or serious diseases who can’t be helped elsewhere come to OU Children’s Physicians. Oklahoma doctors and parents rely on OU Children’s Physicians depth of experience, nationally renowned expertise and sensitivity to children’s emotional needs. In 2009, OU Children’s Physicians opened a new state-ofthe-art facility on the OU Health Sciences Center campus. A year and a half later, the Children’s Atrium was opened creating a new entrance to not only the children’s physician offices, but the hospital as well. The following year, the final piece of this construction project was completed with the opening of the Samis Education Center, further enhancing the campus’ ability to provide the highest quality education services to faculty, staff and students. Many OU Physicians see patients through specialty centers like The Peggy and Charles Stephenson Cancer Center and Harold Hamm Diabetes Center. The Cancer Center building represents the largest public-private biomedical initiative in Oklahoma history. The 210,000 square-foot facility provides

Brian Lynn Offic Brian Maddy, Chief Executive Officer and Lynn Mitchell, M.D., Chief Medical Officer patient-center care, offering the most advanced cancer detection and treatment technology, the largest and most experienced group of cancer specialists, a wide array of supportive services and an environment that provides a warm and comforting experience for patients and caregivers. Members of the Cancer Center - including faculty from OU Health Sciences Center, OU Norman, OU Tulsa, Oklahoma State University and the Oklahoma Medical Research Foundation - conduct innovative and nationally-funded cancer research in the basic, clinical and population sciences. Harold Hamm serves as the focal point for coordinating and expanding numerous avenues of research, patient care, education and prevention that are required to address the diabetes epidemic in a comprehensive manner. The Center offers outreach efforts throughout the state, partnering with communities and other agencies both inside and outside the University of Oklahoma. The Center was established by the University of Oklahoma with the goal of promoting the wellbeing of all people with or at high risk for diabetes in Oklahoma, regardless of ethnic background or financial status. OU Physicians see patients in their offices at the OU Health Sciences Center and in Edmond, Midwest City and other cities around Oklahoma. When hospitalization is necessary, they often admit patients to OU Medical Center. Many also care for their patients in other hospitals around the metro area. OU Physicians serve as faculty at the University of Oklahoma College of Medicine and train the region’s future physicians. For more information about OU Medicine, including OU Physicians and OU Children’s Physicians, go to www.oumedicine.com. OU Physicians faculty and staff are employed by the University of Oklahoma, one of Oklahoma’s largest employers. The university attracts leading faculty and staff from around the world. To view job opportunities within OU Physicians, go to this site: www.oumedicine.com/ouphysicians/job-opportunities

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Member

Tom Gray, President & CEO 655 Research Parkway, Suite 500 Oklahoma City, OK 73104 Phone: 405-319-8150 Fax: 405-319-8168 Website: www.phfokc.com Founded in 1985 with the vision of creating a premier medical center in Oklahoma City, the Presbyterian Health Foundation has invested over $118 million in medical education and research in Oklahoma. This investment has led to medical breakthroughs which touch the lives of individuals and families in communities across the state and nation. It has also brought exciting economic opportunities by positioning Oklahoma at the forefront of genetic research and biotechnology. Proceeds from the 1985 sale of the Presbyterian Hospital were used to create a foundation which would enhance medical research and education in the state of Oklahoma. Trustees of the Presbyterian Hospital continued with the newly formed foundation and believed the potential for excellent health could become the norm, rather than the exception, for all people. Nearly 30 years later, Trustees of the Foundation continue to share a set of values, expectations, and modes of behavior refined under strong leadership and forged by a long history of success that has made a tremendous impact on the people of Oklahoma.

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Over the last decade, Presbyterian Health Foundation developed the PHF Research Park which contains 700,000 square feet of wet lab and office space and provides a place for researchers to translate discovery to solutions, putting science to work solving a specific human health need. Following the 2013 sale of the PHF Research Park to the University of Oklahoma, the Foundation has returned to focusing its efforts on supporting scientific research and medical education at the Oklahoma Health Center Campus. The purpose of the foundation is to provide resources and to encourage the development of medical education and research programs, conducted primarily in Oklahoma. The Foundation concentrates its support in four areas: • Medical Research • Medical Education • Community Health Programs • Technology Transfer Researchers, mentors, administrators and leaders in biotech companies are all part of a community of people who bring to life the ideas of PHF’s mission. PHF will continue its mission to support excellent biomedical science where discovery may be translated to therapies that save and enhance human life. Today, the disclosures in good science, evidenced based knowledge, yield brand new widened horizons of human existence.


Member

Serving Children and Families since 1984

Susan Adams, President & Chief Executive Officer 1301 NE 14th Street Oklahoma City, OK 73117 Phone: (405) 424-6873 Family Room phone (405) 271-2215 Website: www.rmhokc.org When a child is hospitalized or receiving ongoing medical treatment, we believe the love and support of family is as powerful as the strongest medicine. Unfortunately for most parents, being with a hospitalized child means eating out of vending machines and sleeping in chairs or bearing the expense of hotel rooms. That is why Ronald McDonald House Charities® of Oklahoma City is here. Keeping families together . . . when they need it most At 78% of the world’s leading children’s hospitals, families benefit from at least one RMHC Core Program. The Children’s Hospital is served by the 15-BR Ronald McDonald House which has been located at NE 14th St and Lottie for 30 years. • At our House, families can have a bedroom of their own with a comfortable bed, a family-style kitchen

with home-cooked meals, and laundry facilities for their personal use. • Worried moms and dads can talk to one another, sharing their hopes and fears. • For the child who is sick or injured, having a Ronald McDonald House means that they can rest easier, knowing that mom and dad are nearby. The Ronald McDonald Family Room®, located on the sixth floor of The Children’s Hospital, opened in 2008 for dayuse respite services. Parents can relax and regroup just steps away from their child’s bedside.

The positive, comforting environment of both facilities allows the families to focus on their children’s healing process. Services are available to any family with a child 21 years of age or younger receiving medical treatment in Oklahoma City area, regardless of their economic status. Ronald McDonald House Charities of Oklahoma City relies on donors and the community for support of daily operations. No family is ever turned away due to the lack of finances.

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The organization offers career opportunities within the charity, at the House and Family Room to help with the daily operations. For open positions, please visit www.rmhcokc.org/contact/careers. Interested candidates should submit a resume to careers@rmhcokc.org. 29


Member

Dean Gandy, Chief Executive Officer University Hospitals Authority & Trust PO Box 26307 Oklahoma City, OK 73126 Phone: 405-271-4962 Website: www.universityhospitalsauthority.com The University Hospitals Authority and Trust are a state agency and a public trust of the state of Oklahoma. Key facts: • Formed as part of an historic agreement more than a decade and a half ago that united the state, a private corporation (HCA) and the University of Oklahoma in a partnership that created the OU Medical Center and united the adult hospitals with The Children’s Hospital at OU Medical Center. • Mission - To be a catalyst for medical excellence, to support medical education and research and to help assure quality health care for all Oklahomans. • Through its leadership, state and federal resources are maximized to ensure a dependable source of revenue for growth and development with a goal of supporting improved health for every Oklahoman. • The Authority and Trust provide support for important educational enhancements, for key research and health care advancements and for critical capital improvement projects at the OU Health Sciences Center Key projects funded to date include: • Construction of the new Children’s Atrium. This beautiful, architectural gem will serve as a new front door for The Children’s Hospital at OU Medical Center and the OU Children’s Physicians Building, as well as a unique space catering to the young patients of both facilities and their families. • Construction of Samis Education & Conference Center for the OUHSC campus, completed in 2012. It’s three-story design provides state-of-the-art meeting rooms, board rooms and auditorium space to accommodate a wide variety of meeting needs. • Support of facility enhancement and expansion project for Dean McGee Eye Institute 30

• The OU Children’s Physicians Building, completed in 2009. Located at the corner of NE 13th and Phillips, it provides 336,000 square feet of state-of-theart medical office space designed specifically with the needs of young patients and their families in mind. It is home to more than 100 pediatric specialists and the first free-standing first, freestanding, pediatric multi-specialty, medical office building in the state. • Support of the new Clinical Skills Testing and Education Center at the OU Health Sciences Center, in conjunction with other generous donors. This facility offers cutting-edge medical simulation equipment and facilities, as well as a new robot-assisted surgical training facility. • Support of Phase Two of the Stanton L. Young Biomedical Research Center. A hub of research of activity on campus, the facility more than doubled in size with the completion of phase two, providing more research space where top scientists continue their nationally and internationally renowned work in biomedicine, cancer, genetics and more. • The OU Physicians Building, completed in 2001. Located at the corner of NE 10th and Phillips, the OU Physicians Building is home to more than 130 physicians, with expertise in a wide range of medical specialties. The building provides an environment where patient care and the newest technology come together under one roof. • A facility enhancement project for the OU College of Dentistry that included much-needed upgrades and technological enhancements aimed at elevating the training of Oklahoma’s future dentists to a new level of excellence.


Member

Jason R. Sanders, MD Senior Vice President and Provost P.O. Box 26901, LIB 221 Oklahoma City, OK 73126 Phone: (405) 271-3223 Website: www.ouhsc.edu

In education, research and patient care, the University of Oklahoma Health Sciences Center is the state’s premier academic health center and regional leader in meeting the challenges of 21st-century health care. The most concentrated source of medical expertise in Oklahoma, the OU Health Sciences Center’s new facilities and new technology -- plus an internationally prominent faculty -- place it at the leading edge of the nation’s institutions of medical education. One of only four comprehensive academic health centers in the nation with seven professional schools, the OU Health Sciences Center serves more than 3,800 students enrolled in more than 70 health professions, graduate and undergraduate programs on the Oklahoma City campus and at the Schusterman Center at the University of Oklahoma-Tulsa. In addition, more than 700 physicians are receiving residency training in Oklahoma City and Tulsa. Research, training grants and contracts, and sponsored program activities at the OU Health Sciences Center totaled more than $120 million

in FY 2013. With a budget of over $870 million, OUHSC employs more than 1,200 full time faculty and 4,000 staff. More than half of all NIH expenditures in the state of Oklahoma result from OU Health Sciences Center research. The OU Health Sciences Center serves as the state’s training facility for physicians, biomedical scientists, nurses, dentists, pharmacists and a wide range of allied health and public health professionals. The OU Health Sciences Center is known for its research programs in cellular and molecular medicine, gene regulation, structural biology, cancer, diabetes, microbiology and immunology, vision, cardiovascular physiology, neuroscience and pharmaceutical sciences. The center’s growing faculty and facilities offer unparalleled opportunities for students, patient care and the development of the biomedical industry in Oklahoma. OU Health Sciences Center-developed technology is advancing the economy of Oklahoma. Companies that commercialize technology created by OU Health Sciences Center researchers have been established in Oklahoma City. OU has become one of the primary centers in the world for genome studies, with the Norman campus contributing to the human genome project and the OUHSC campus providing a number of microbial pathogen genomes. The OU Health Sciences Center ranks second in the world for the number of microbial genomes being sequenced. CONTINUED

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Member Two-thirds of all Oklahoma physicians, half of the state’s dentists and a significant percentage of Oklahoma’s other health care professionals earned their degrees from the OU Health Sciences Center. In addition, the seven OU Health Sciences Center colleges are the primary source of continuing education for the state’s health care professionals. The scientists, scholars and clinicians appointed to the OU Health Sciences Center faculty stand at the leading edge of their profession. They not only train the next generation of health care providers and researchers,

With cancer being one of the leading causes of death in the United States, The Peggy and Charles Stephenson Cancer Center opened in June 2011. This cancer center allows the people of Oklahoma to receive world-class treatment without leaving the state and is staffed with some of the nation’s finest cancer physicians. It offers state-of-the-art technology, unparalleled cancer research programs, and bench-to-bedside care.

many are themselves practicing professionals actively involved in improving the lives and health of Oklahomans. The clinical practice of the OU College of Medicine is provided through OU Physicians. These physicians represent the largest multi-specialty medical group in the state with more than 500 physicians, offering almost every adult and child specialty. OU Physicians accepts referrals from across the state and region and care for hospital patients at the OU Medical Center. OU Children’s Physicians is an integral part of OU Physicians.

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The Harold Hamm Diabetes Center is a comprehensive treatment, research, and educational facility dedicated to eliminating and controlling the effects of all types of diabetes. The Diabetes Center is at the forefront in diabetes-related research, and OUHSC physician researchers are specialists in diabetes care and utilize cutting edge research for the best treatment available research.


Associate Member

Mark W. Kelly, President and CEO 3001 N Lincoln Blvd Oklahoma City, OK 73105 For all locations visit: https://www.oecu.org/locations/ Phone: 405.606.6328 Website: www.oecu.org Oklahoma Employees Credit Union (OECU) has been serving Oklahoman’s since 1954 as a member-owned financial cooperative. Since 1954, OECU’s membership has grown from 19 charter members to over 42,000 members. OECU is a not-for-profit financial institution that returns profits back to members in the form of low or no fee services, higher rates on deposits and more competitive loan rates.

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Associate Member

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