BEAUTY

non-inflammatory ones Two distinct, partially overlapping, processes need to be addressed during the treatment of acne One is accelerating the healing of the ongoing lesions and the other one is to prevent the huge number of sebaceous glands prone to enter the acne cycle. Therefore, the key strategic targets in acne care appear to be the pilosebaceous follicle that is not yet involved in the acne cycle and the second one is to adequately control the key switching factors of comedone for mation for long ter m relief. A multi-tasking strategy is needed to improve the conditions of acne-affected skin Taking all these factors into consideration, we will address key targets governing acne therapy while preventing hyperpigmentation issues Discussions will also include reasons for selecting ingredients for mitigating acne-affected skin

n Ratan K. Chaudhuri, Ph.D.

Dr. Chaudhuri is President and CEO of Sytheon, which he founded in 2006. Sytheon is an innovative global specialty ingredient company Sytheon’s global headquarters is in Parsippany, New Jersey, USA with its two affiliates in France and Singapore Ratan is a humble entrepreneur by heart and a thinker with strong leadership skills He has developed numerous best-in-class products for the personal care industry, just to name two recent gold standards – Sytenol A (Bakuchiol) and Synovea HR (Hexylresorcinol) Ratan holds over 100 U S and international patents and has over 100 publications including six book chapters. Ratan has been named as one of the top 10 inspiring business leaders by Inc Magazine to watch in 2022 He can be reached by telephone (+1 201-303-5594) or e-mail (ratan@sytheonltd com)

Hilary Baldwin (Acne Treatment and Research Center)

In this presentation, we will address challenges in topical and oral acne treatment Topical retinoids are the mainstay of acne therapy They improve existing lesions, and prevent the development of the microcomedones, which are the predecessors of future lesions. However, topical retinoids can be irritating, especially in the first few weeks of treatment This often leads to inconsistent use or discontinuation. Benzoyl peroxide is a highly effective, rapid-onset antibacterial which does not promote the development of bacterial resistance It also decreases the development of antibacterial resistance to both topical and oral antibiotics with which is it used in combination Unfortunately, benzoyl peroxide is a concentration-dependent irritant it bleaches fabric and is an uncommon sensitizer.

Oral antibiotics are highly effective in treating the inflammatory lesions of acne However, the effects are rarely durable resulting in overuse and the development of bacterial resistance. Pregnant and lactating women often experience acne Unfortunately, clinical trials do not include this population and as such, little exists in the way of efficacy or safety data As a result, these patients are generally told by their obstetricians to forgo treatment until delivery/weaning regardless of the severity of their disease

Isotretinoin can be used to treat the most severe cases of acne and 80% of those who complete a course will not need acne treatment again. It should be noted that there are many potential side effects of the drug, most of which are easily managed The inter net tells a different story, however, frightening patients with misinfor mation.

Hilary Baldwin is a board-certified der matologist and Medical Director of the Acne Treatment and Research Center in Brooklyn, New York She is a Clinical Associate Professor of Der matology at Rutgers Robert Wood Johnson Medical Center Dr Baldwin has interests in acne, rosacea, keloidal scarring, cosmeceuticals, and the skin microbiome. She is a frequent national and inter national lecturer and visiting professor, and her work has been published extensively in der matology jour nals. Dr. Baldwin served as a founding board member and second president of the American Acne and Rosacea Society