NYSCC Acne Care Symposium

June 14, 2023 • 9:00 a.m. – 6:00 p.m.

Don’t miss this full-day symposium, which will include podium presentations from a line-up of inter nationally recognized experts in acne care as well as a technology poster session for attendees to interact with researchers in the field. The event will be held at the beautiful Fairleigh Dickinson University Florham Campus located in Madison, New Jersey

The campus consists of 178 acres, which is the for mer country estate of early 20th-century socialites Florence Vanderbilt and Hamilton Twombly.

Fairleigh Dickinson University instituted a Master of Science degree program in Cosmetic Science in 1982 one of the first of its kind It maintains close ties with the cosmetic industry where most of its professors come from leading institutions within industry, offering students a strong academic and practical approach to creating novel products

Event Chairs

• Roger L. McMullen, Ph.D. (Ashland, Inc.); e-mail: roger mcmullen@fdu edu

• Miao Wang (L’Oréal USA)

Registration

To register for this symposium, go to the Events section of NYSCC website (www.nyscc.org)

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Agenda:

9:00 a.m. – 9:45 a.m. Registration

9:45 a.m. – 10:00 a.m.

10:00 a m – 10:30 a m

Opening Remarks

Acne Update: What's New and What's True

– Mary Wu Chang, M.D. (University of Connecticut School of Medicine)

Key Strategic Targets for Mitigating Acne-Affected Skin

– Ratan K. Chaudhuri, Ph.D (Sytheon Ltd.)

11:00 a.m. – 11:15 a.m. Break 11:15 a.m. – 11:45 a.m.

Challenges Commonly Encountered with Acne Therapy

– Hilary Baldwin, M.D. (Acne Treatment and Research Center) 11:45 a m – 12:15 p m

Multi-modal and 3D Imaging for Objective Evaluation of Acne

– Sachin V. Patwardhan, Ph.D (Canfield Scientific Inc.) 12:15 p.m. – 12:45 p.m.

Category Insights and Consumer Trends

– Francine Krenicki (Crown Laboratories)

12:45 p m – 2:15 p m Poster Session and Lunch

2:15 p m – 2:45 p m

Cutibacterium Acnes, Phages, and Acne

– Nathan Brown, Ph.D. (Parallel Health)

2:45 p m – 3:15 p m

Evaluation of Microbiome Changes Related to Cleanser Use in Healthy and Acne Prone Skin

– Amina Bouslimani, Ph.D. (L’Oréal USA)

3:15 p.m. – 3:45 p.m. Troubled Skin, Inflammasomes, and the Skin’s Innate Immune Response: Is Targeting C. Acnes Enough?

– James V. Gruber (Vantage Specialties)

3:45 p m – 4:00 p m Break

4:00 p m – 4:30 p m Acne Vulgaris in the United States: Burden of Disease and Prescribing Trends

– Ayman Grada M.D. (Case Western Reserve University School of Medicine)

4:30 p.m. – 5:00 p.m. What If the Rules of Fighting Acne Have Changed?

Sophia Bull (Lucas Meyer Cosmetics)

5:00 p m – 6:00 p m Cocktail Reception

Symposium Location

Fairleigh Dickinson University

Florham Campus, Lenfell Hall (located in Hennessy Hall – #7 on the map)

285 Madison Avenue, Madison, New Jersey (continued on Page 12)

n Chair – Roger L. McMullen, Ph.D.

Roger has over 20 years of experience in the personal care industry with specialties in optics, imaging, and spectroscopy of hair and skin. Currently, he is a Principal Scientist at Ashland Inc and leads the Material Science team in the Measurement Science department. Roger has over 50 publications in peerreviewed jour nals and textbooks He is also the author of Antioxidants and the Skin, 2nd edition and founded the online news magazine The Cosmetic Chemist Roger received a B.S. in Chemistry from Saint Vincent College and completed his Ph D in Biophysical Chemistry from Seton Hall University n Co-Chair – Miao Wang

Roger actively engages and participates in educational activities in the personal care industry He frequently teaches continuing education courses for the SCC and TRI-Princeton In addition, Roger is an Adjunct Professor at Fairleigh Dickinson University and teaches Biochemistry to students pursuing M S degrees in Cosmetic Science and Phar maceutical Chemistry Prior to pursuing a career in science, Roger served in the U S Navy for four years on board the USS YORKTOWN (CG 48) He is fluent in Spanish and Catalan and currently is lear ning to play the classical guitar.

Miao Wang is an Assistant V ice President at L'Oréal Advanced Research, leading the Inter national Innovative Ingredients team in the U S She has over 20 years of experience in research, innovation, and product development in the Personal Care industry, with extensive capabilities in leading multi-disciplinary teams in building innovation pipelines and roadmaps launching disruptive and fast track technologies, developing strategic relationships with exter nal partners and inter nal stakeholders, and assessing and integrating new collaboration partners to grow U.S. ecosystems supporting green science. Miao has led the team to successfully transfor m innovation to launches with brands of CeraVe, Kiehl's, Maybelline New York, SkinCeuticals, L'Oréal Paris, Gar nier, Carol's Daughter, Urban Decay, and NYX to address consumer needs. Miao has a B.S.E. in Chemical Engineering and M.S. in Applied Phar maceutical Science Miao has over 70 patents and publications and serves as an industrial advisor on board committees.

Moderator –

Ramine Parsa is currently a Research Manager and Fellow at Kenvue

Previously part of the Johnson & Johnson family of companies, Kenvue is now a separate publicly traded company as of May 2023. Ramine has 12 years of experience at Johnson & Johnson Consumer in bringing innovation and scientific insights to the commercial pipeline for skin health. Prior to joining Johnson & Johnson, he held various roles in biotechnology startups in consumer health with an emphasis on der matology and eye care He received his Ph D in Molecular and Cellular Endocrinology from the University of Sciences of Pierre et Marie Curie in France Ramine is the inventor of 16 granted patents and co-author of 10 peer-reviewed research publications. He is a mentor to new scientists and scholars. Throughout his career, Ramine has received multiple scientific awards including the 2021 Johnson Medal for his work on Acetyl Dipeptide n Moderator – Gopinathan K. Menon, Ph.D.

Gopinathan K. Menon obtained his M.S. and Ph.D. degrees from the University of Baroda, India, and also held a faculty position in the same university

In 1979, he spent a year as a Homi Bhabha Fellow and V isiting Professor at Michigan State University where he trained in electron microscopy of skin In a subsequent sabbatical at the Elias laboratory in University of Califor nia, San Francisco (UCSF), from 1982-1984, he began his focus on skin barrier, and in 1988 moved to San Francisco as a full-time Research Faculty in Der matology at UCSF

From 1993 to 2017, he held various research positions in the personal care industry in the United States, including Principal Research Fellow and Head, Skin Biology Research at Avon Products and Senior Research Fellow at Inter national Specialty Products (later merged with Ashland, Inc ) Presently, he is a Fellow of the Califor nia Academy of Sciences, San Francisco.

His honors include being awarded a Homi Bhabha Fellowship, elected as a Fellow of the Califor nia Academy of Sciences, Chair of the Gordon Research Conference on Barrier Function of Mammalian Skin (2011), and induction to the GRC Chairs’ Hall of Fame (2012) He has been an invited speaker at national and inter national meetings and has over a hundred publications that include peer reviewed research papers, reviews, and book chapters

Bret Clark is a Technical Leader in the Spectroscopy department at Ashland Specialty Ingredients with a focus on NMR and infrared spectroscopy He is active in both the NYSCC and the New York-New Jersey ACS Spectroscopy group He ear ned a B S in Chemistry at Rutgers University and an M S in Analytical and Organic Chemistry at Seton Hall University.

Acne is the most common skin condition in the United States, affecting up to 50 million Americans annually Approximately 85% of people between the ages of 12 and 24 have acne Adult acne is increasing, and now affects up to 15 percent of women This talk will begin with a look at different types of acne and review the medications in the der matologist's ar mamentarium.

n Mary Wu Chang,

Dr Chang is a board-certified dermatologist and pediatric dermatologist with over 26 years ' experience. After graduating from University of W isconsin School of Medicine and Public Health, she went on to complete a pediatrics residency at Kaiser San Francisco followed by a der matology residency at Wayne State University she served as Chief Resident for both residencies. Dr. Chang then joined the full-time faculty at NYU Medical Center for 7 years before moving to Connecticut in 2005. Currently, Dr. Chang is Associate Professor of Der matology and Pediatrics at the University of Connecticut School of Medicine where she runs a busy clinic and enjoys teaching medical students as well as der matology and pediatric resident physicians. She has published extensively in the literature and frequently lectures regionally and nationally Her interests include hemangiomas and vascular malfor mations, severe acne, atopic der matitis, and clinical drug trials.

We have come a long way since 1896, when it was suggested that Propionibacterium acnes found in acne lesions was the cause of acne Recently, high resolution core genome analysis combining 16S rRNA gene sequences led to changing the name of P. acnes to Cutibacterium acnes (Scholtz et al , Int J Sys Evo Microbiol , 66: 4422-4432, 2016) While the commensal bacterium

C. acnes is involved in the maintenance of healthy skin, it can also act as an opportunistic pathogen in acne vulgaris Recent studies have shown that the relative abundance of C acnes (in metagenomics studies) is similar among patients with acne and healthy individuals (87%–89%) or even higher in healthy subjects (89% to 94%) Multiple studies highlighted that the severity of acne might not only be due to a specific C acnes strain but also due to host and environmental factors Early and intense inflammatory events in the epider mis have indeed been shown to contribute to the development of acne.

Typically, the mean lifetime of each acne lesion is a few days for inflammatory and a few weeks for (continued on Page 14)