Prof Dr Mohamed Hamed

In IMH (mammals and Birds): Brain: 1-Diffuse non-suppurative meningoencephalitis. It is characterized by mononuclear cell infiltration and leukoencephalomalacia.

2-Tachyzoites (crescentic or round bodies) inside the neurons and astrocytes.

3-Tissue cysts (containing more than 50 bradyzoites without inflammatory cells.

4-Small areas of necrosis and calcification.

Liver: 1-Focalcoagulative necrosis.

2-Tachyzoites inside the hepatic and kupffer cells.

3-Tissue cysts containing bradyzoites are seen.

Lungs: 1-Small gray (tumor-like) nodules on the lungs.

2-Tachyzoites inside the type I and II pneumocytes and bronchial epithelium.

3-Focal necrosis with alveolar fetalization or pulmonary adenomatosis.

4-Lymphocytes and macrophages infiltration and inside the alveoli.