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Technical Manual, 16th edition Technical Manual, 15th edition Technical Manual, 14th edition Technical Manual, 13th edition Technical Manual, 12th edition Standards, 1st-26th editions Tutorial About the AABB

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Technical Manual, 16th ed.

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1. Quality Systems: Theory and Practice 2. Facilities, Work Environment, and Safety 3. Regulatory Issues in Blood Banking 4. Disaster Management

7. Blood Component Collection by Apheresis 8. Infectious Disease Screening

9. Storage, Monitoring, Pretransfusion Processing, and Distribution of Blood Components 10. Molecular Biology and Immunology in Transfusion Medicine 11. Blood Group Genetics

5. Allogeneic and Autologous Blood Donor Selection 6. Whole Blood Collection and Component Processing

E D I T I O N S

12. ABO, H, and Lewis Blood Groups and Structurally Related Antigens 13. The Rh System 14. Other Blood Groups 15. Pretransfusion Testing 16. Identification of Antibodies to Red Cell Antigens

Chapters 17 - 32

Chapters, 16th ed.

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17. The Positive Direct Antiglobulin Test and Immune-Mediated Hemolysis 18. Platelet and Granulocyte Antigens and Antibodies 19. The HLA System 20. Hemotherapy Decisions and Their Outcomes 21. Administration of Blood Components 22. Perinatal Issues in Transfusion Practice 23. Neonatal and Pediatric Transfusion Practice 24. Blood Management

Chapters, 16th ed.

E D I T I O N S

25. Transfusion Support for Hematopoietic Transplant Recipients 26. Therapeutic Apheresis 27. Noninfectious Complications of Blood Transfusion 28. Approaches to Blood Utilization Auditing 29. Collecting and Processing Marrow Products for Transplantation 30. Hematopoietic Progenitor Cells Collected by Apheresis 31. Umbilical Cord Blood

32. Tissue and Organ Transplantation and the Hospital Tissue Transplantation Service Chapters 1 - 16 M A I N

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Methods

Appendices

1. General Laboratory Methods

APPENDIX 1 Normal Values in Adults

2. Red Cell Typing 3. Antibody Detection, Identification, and Compatibility Testing 4. Investigation of a Positive DAT 5. Hemolytic Disease of the Fetus and Newborn 6. Blood Collection, Component Preparation, and Storage 7. Transplantation of Cells and Tissue 8. Quality Control

APPENDIX 2 Selected Normal Values in Children APPENDIX 3 Typical Normal Values in Tests of Hemostasis and Coagulation (Adults) APPENDIX 4 Coagulation Factor Values in Platelet Concentrates APPENDIX 5 Approximate Normal Values for Red Cell, Plasma, and Blood Volumes

Appendices 6 - 11

Methods/Appendices, 16th ed.

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APPENDIX 6 Blood Group Antigens Assigned to Systems

APPENDIX 9 Distribution of ABO/Rh Phenotypes by Race or Ethnicity

APPENDIX 7 Examples of Gene, Antigen, and Phenotype Symbols in Conventional and International Society of Blood Transfusion Terminology

APPENDIX 10 Directory of Organizations APPENDIX 11 Resources for Safety Information

APPENDIX 8 Examples of Correct and Incorrect Terminology

Appendices 1 - 5

Appendices, 16th ed.

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Technical Manual, 15th ed.

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1. Quality Systems

E D I T I O N S

9. Molecular Biology in Transfusion Medicine

2. Facilities and Safety 3. Blood Utilization Management

10. Blood Group Genetics 11. Immunology

4. Allogeneic Donor Selection and Blood Collection

12. Red Cell Antigen-Antibody Reactions and Their Detection

5. Autologous Blood Donation and Transfusion

13. ABO, H, and Lewis Blood Groups and Structurally Related Antigens

6. Apheresis

14. The Rh System

7. Blood Component Testing and Labeling

15. Other Blood Groups

8. Collection, Preparation, Storage, and Distribution of Components from Whole Blood Donations

16. Platelet and Granulocyte Antigens and Antibodies

Chapters 17 - 28

Chapters, 15th ed.

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17. The HLA System

23. Perinatal Issues in Transfusion Practice

18. Pretransfusion Testing 19. Initial Detection and Identification of Alloantibodies to Red Cell Antigens 20. The Positive Direct Antiglobulin Test and Immune-Mediated Red Cell Destruction 21. Blood Transfusion Practice 22. Administration of Blood and Components

E D I T I O N S

24. Neonatal and Pediatric Transfusion Practice 25. Cell Therapy and Cellular Product Transplantation 26. Tissue and Organ Transplantation 27. Noninfectious Complications of Blood Transfusion 28. Transfusion-Transmitted Diseases

Chapters 1 - 16

Chapters, 15th ed.

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Methods Introduction 1. General Laboratory Methods 2. Red Cell Typing 3. Antibody Detection, Antibody Identification, and Serologic Compatibility Testing

5. Hemolytic Disease of the Fetus and Newborn 6. Blood Collection, Storage, and Component Preparation 7. Quality Control Appendices

4. Investigation of a Positive Direct Antiglobulin Test

Methods/Appendices, 15th ed.

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APPENDIX 1 Normal Values in Adults APPENDIX 2 Selected Normal Values in Children APPENDIX 3 Typical Normal Values in Tests of Hemostasis and Coagulation APPENDIX 4 Coagulation Factor Values in Platelet Concentrates APPENDIX 5 Approximate Normal Values for Red Cell, Plasma, and Blood Volumes APPENDIX 6 Blood Group Antigens Assigned to Systems

Appendices, 15th ed.

E D I T I O N S

APPENDIX 7 Examples of Gene, Antigen, and Phenotype Terms APPENDIX 8 Examples of Correct and Incorrect Terminology APPENDIX 9 Distribution of ABO/Rh Phenotypes by Race or Ethnicity APPENDIX 10 Suggested Quality Control Performance Intervals APPENDIX 11 Directory of Organizations APPENDIX 12 Resources for Safety Information M A I N

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Technical Manual, 14th ed.

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1. Quality Systems

E D I T I O N S

9. Molecular Biology in Transfusion Medicine

2. Facilities and Safety 3. Blood Utilization Management

10. Blood Group Genetics 11. Immunology

4. Donor Selection and Blood Collection

12. Red Cell Antigen-Antibody Reactions and Their Detection

5. Autologous Blood Donation and Transfusion

13. ABO, H, and Lewis Blood Groups and Structurally Related Antigens

6. Apheresis 7. Blood Components Testing and Labeling

14. The Rh System

8. Preparation, Storage, and Distribution of Components from Whole Blood Donations

15. Other Blood Groups 16. Platelets and Granulocyte Antigens and Antibodies

Chapters 17 - 28

Chapters, 14th ed.

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17. The HLA System

23. Prenatal Issues in Transfusion Practice

18. Pretransfusion Testing 19. Initial Detection and Identification of Alloantibodies to Red Cell Antigens 20. The Positive Direct Antiglobulin Test and Immune-Mediated Red Cell Destruction 21. Blood Transfusion Practice

E D I T I O N S

24. Neonatal and Pediatric Transfusion Practice 25. Hematopoietic Transplantation 26. Tissue and Organ Transplantation 27. Noninfectious Complications of Blood Transfusion 28. Transfusion-Transmitted Diseases

22. Administration of Blood and Components

Chapters 1 - 16

Chapters, 14th ed.

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Methods Introduction 1. General Laboratory Methods

5. Hemolytic Disease of the Newborn Methods

2. Red Cell Typing Methods

6. Blood Collection, Storage, and Component Preparation Methods

3. Antibody Detection, Antibody Identification, and Serologic Compatibility Testing Methods

7. Processing Hematopoietic Progenitor Cells Methods

4. I nvestigation of a Positive Direct Antiglobulin Test Methods

Methods/Appendices, 14th ed.

8. Quality Control Methods Appendices

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APPENDIX 1 Normal Values in Adults APPENDIX 2 Selected Normal Values in Children APPENDIX 3 Typical Normal Values in Tests of Hemostasis and Coagulation (Adults) APPENDIX 4 Coagulation Factor Values in Platelet Concentrates APPENDIX 5 Approximate Normal Values for Red Cell, Plasma, and Blood Volumes

Appendices, 14th ed.

E D I T I O N S

APPENDIX 6 Blood Group Antigens Assigned to Systems APPENDIX 7 Suggested Quality Control Performance Intervals APPENDIX 8 Directory of Organizations APPENDIX 9 Resources for Safety Information APPENDIX 10 AABB-Accredited Immunohematology Reference Laboratories APPENDIX 11 AABB-Accredited Parentage Testing Laboratories M A I N

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Technical Manual, 13th ed.

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E D I T I O N S

9. Molecular Biology in Transfusion Medicine

2. Facilities and Safety 3. Blood Utilization Management

10. Blood Group Genetics 11. Immunology

4. Donor Selection and Blood Collection

12. Red Cell Antigen-Antibody Reactions and Their Detection

5. Autologous Blood Donation and Transfusion

13. ABO, H, and Lewis Blood Groups and Structurally Related Antigens

6. Apheresis 7. Blood Components Testing and Labeling

14. The Rh System

8. Blood Component Preparation, Storage, Shipping, and Transportation

15. Other Blood Groups 16. Platelets and Granulocyte Antigens and Antibodies

Chapters 17 - 28

Chapters, 13th ed.

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17. The HLA System

E D I T I O N S

23. Perinatal Concerns in Transfusion Practice

18. Pretransfusion Testing 19. Initial Detection and Identification of Alloantibodies to Red Cell Antigens 20. The Positive Direct Antiglobulin Test and Immune-Mediated Red Cell Destruction

24. Neonatal and Pediatric Transfusion Practice 25. Hematopoietic Transplantation 26. Tissue Banking and Solid Organ Transplantation

21. Blood Transfusion Practice

27. Noninfectious Complications of Blood Transfusion

22. Administration of Blood and Components

28. Infectious Complications of Blood Transfusion

Chapters 1 - 16

Chapters, 13th ed.

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Methods Introduction 1. General Laboratory Methods

5. Hemolytic Disease of the Newborn Methods

2. Red Cell Typing Methods

6. Blood Collection, Storage, and Component Preparation Methods

3. Antibody Detection, Antibody Identification, and Serologic Compatibility Testing Methods

7. Quality Control for Equipment Methods

4. I nvestigation of a Positive Direct Antiglobulin Test Methods

Methods/Appendices, 13th ed.

Appendices

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Technical Manual, 12th ed.

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1. Quality Assurance

9. Blood Group Genetics

2. Safety

10. Immunology

3. Blood Utilization Management

11. Red Cell Antigen-Antibody Reactions and Their Detection

4. Donor Selection and Blood Collection 5. Autologous Blood Collection and Transfusion 6. Hemapheresis 7. Blood and Components 8. Molecular Biology in Transfusion Medicine

12. ABO, H, and Lewis Blood Groups and Structurally Related Antigens 13. The Rh System 14. Other Blood Groups 15. The HLA System 16. Pretransfusion Testing Chapters 17 - 26

Chapters, 12th ed.

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17. Identification of Alloantibodies to Red Cell Antigens

22. Neonatal and Pediatric Transfusion Practice

18. The Positive DAT and ImmuneMediated Red Cell Destruction

23. Hematopoietic Stem and Progenitor Cells

19. Blood Transfusion Practice

24. Tissue Banking and Organ Transplantation

20. Administration of Blood and Components 21. Obstetric & Perinatal Transfusion Practice

25. Noninfectious Complications of Blood Transfusion 26. Infectious Complications of Blood Transfusion

Chapters 1 - 16

Chapters, 12th ed.

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1. General Laboratory Methods 2. Red Cell Typing 3. Antibody Detection and Compatibility Testing 4. Use of Antibody Titration, Alloantibody Identification, and the Rare Donor File 5. Elution

Methods/Appendices, 12th ed.

6. Immune Hemolysis, Autoantibodies, and Drugs 7. Hemolytic Disease of the Newborn 8. Testing Donor Blood 9. Blood Collection, Storage, and Component Preparation 10. Quality Control Appendices

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1st Edition (1958)

9th Edition (1978)

18th Edition (1997)

2nd Edition (1960)

10th Edition (1981)

19th Edition (1999)

3rd Edition (1962)

11th Edition (1984)

20th Edition (2000)

4th Edition (1963)

12th Edition (1987)

21st Edition (2002)

5th Edition (1970)

13th Edition (1989)

22nd Edition (2003)

6th Edition (1972)

14th Edition (1991)

23rd Edition (2005)

7th Edition (1974)

15th Edition (1993)

24th Edition (2006)

8th Edition (1976)

16th Edition (1994)

25th Edition (2008)

17th Edition (1996)

26th Edition (2009)

Standards

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This short tour will show you some of the navigation features of Adobe Acrobat. When you click on the Start button below, you will jump to a sample page that includes a blue Note at the top. Follow the directions in the Note to continue on the tour. A Note provides you with helpful information. Click the Green Note below for an example: START

Tutorial

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Established in 1947, AABB is an international, not-for-profit association dedicated to the advancement of science and the practice of transfusion medicine and related biological therapies. It is committed to improving health by developing and delivering standards, accreditation, and educational programs and services that optimize patient and donor care and safety. For more detailed information, visit AABB’s Web site at www.aabb.org. Other related publications from AABB: Technical Manual, 16th Edition (print) Edited by John D. Roback, MD; Martha Rae Combs, MT(ASCP)SBB; Brenda J. Grossman, MD; and Christopher D. Hillyer, MD

Transfusion Therapy: Clinical Principles and Practice, 2nd Edition

Blood Transfusion Therapy: A Physician’s Handbook, 9th Edition Edited by Karen King, MD, and Jerome L. Gottschall, MD

Practical Guide to Transfusion Medicine, 2nd Edition

Edited by Paul D. Mintz, MD

By Marian Petrides, MD; Gary Stack, MD, PhD; Laura Cooling, MD, MS; and Lanne Y. Maes, MD

Transfusion Medicine Self-Assessment and Review, 2nd Edition

Transfusion Medicine Interactive: A Case Study Approach CD-ROM

By Douglas P. Blackall, MD; Priscella Figueroa, MD; and Jeffrey L. Winters, MD

About the AABB

By Marian Petrides, MD; Roby Rogers, MD; and Nora Ratcliffe, MD

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Below is a short summary of Adobe Reader Tools. For a more detailed description, refer to the Adobe Reader Help on the toolbar above. Some of the tools listed on the following pages will be visible only if you click on the small More Tools arrows and select Expand This Button. NAVIGATION PANE Allows you to display/hide bookmarks or thumbnail views of pages. To improve your view of the bookmarks, click on the border between the bookmark window and the page window and drag the border to the right. Click on the bookmark or page tab to view bookmarks or thumbnails.

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SEARCH TOOLS Search the information you need by a title, word, or string of words in a matter of seconds. Search allows you to search the entire database. Select Search and select desired options in the dialogue box, enter word or string of words, and select Search Button. For a detailed description of the search dialog box and proximity searching, refer to the Search Techniques section of the help file listed on the toolbar above.

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LINKS Click any text that is identified as a hypertext link (or colorized box). The pointer changes to a pointing finger when positioned over a link. Blue boxes link to standards, red boxes link to references, yellow boxes link to methods, green boxes link to tables or figures, and pink boxes link to chapters. PRINTING Click the Print button to print a single page, selected pages, or the entire document.

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