Systemic pathology new (updated)

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o Numerous neutrophils  Urinary Symptoms o Weight loss o Frequency, mild Lumbar pain o Hematuria TUBERCULOUS BONE : Site :: Thoraic & Lumbar vertebras, Bones of hips, Knee, angle, elbow, wrist Feature :: Caseous granulomas Cold abscess :: Liquified caseous of muscle redness / heat φ LYMPH NODE TB : Pathologic Site :: Pulmonary hilar mode with primary complex, Cervical nodes NE : enlarge, mat together/ cheesy material LM : numerous granulomas 5. THE TERMS: CASEOUS NECROSIS, EPITHELIOID CELL, LANGHAN’S GIANT CELL, GRANULOMA, COLD ABSCESS, GHON’S COMPLEX (PRIMARY COMPLEX), SECONDARY TUBERCULOSIS, TUBERCULOMA. CASEOUS NECROSIS NE : thick, pasty, homogenous, pale yellow-white substance LM : Eosinophilic substance, homogeneous, lipid – rich, structure less [no interstitial fibrous tissue] EPITHELOID CELLS Activated macrophages resembling epithelial cells.  Plentiful, eosinophilic cytoplasm  Oval vesicular nucleus LANGHAN’S GAINT CELL  Plentiful pink cytoplasm, multi – nuclei  Marginal ring – arranged

GRANULOMA Collection of immune cells known as granulocytes found in an inflammation. COLD ABSCESS 42 | P a g e


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