Bacteriology classification of bacteria & select gram ⊕ & gram ⊝ infections

Gram-negative Organisms (2) Pseudomonas infection PSEUDOMONAS is associated with:  Pseudomonas aeruginosa is an Pneumonia, pyocyanin opportunistic aerobic, motile, gram Sepsis ⊝ rod (bacillus ) Ecthyma gangrenosum  Non-lactose fermenting, oxidase ⊕ UTIs  Produces pyocyanin (blue-green Diabetes, drug use pigment); has a grape-like odor Osteomyelitis (e.g., puncture wounds)  Produces endotoxin (fever, shock) Mucoid polysaccharide capsule  exotoxin A (inactivates EF-2) Otitis externa (swimmer’s ear)  phospholipase C (degrades cell Ecthyma gangrenosum Nosocomial infections (catheters, membranes) and rapidly progressive, necrotic cutaneous lesion caused by equipment)  pyocyanin (generates reactive Pseudomonas bacteremia. exotoxin A oxygen species) Immunocompromised pts.

Skin infections (hot tub folliculitis)