JBP - Volume 42, number 5, September-October 2016

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Berton DC, Santos AH, Bohn I Jr, Lima RQ, Breda V, Teixeira PJZ

30. Decramer ML, Chapman KR, Dahl R, Frith P, Devouassoux G, Fritscher C, et al. Once-daily indacaterol versus tiotropium for patients with severe chronic obstructive pulmonary disease (INVIGORATE): a randomised, blinded, parallel-group study. Lancet Respir Med. 2013;1(7):524-33. http://dx.doi.org/10.1016/S2213-2600(13)70158-9 31. O’Donnell DE, Laveneziana P, Webb K, Neder JA. Chronic obstructive pulmonary disease: clinical integrative physiology. Clin Chest Med. 2014;35(1): 51-69. http://dx.doi.org/10.1016/j.ccm.2013.09.008 32. Trevethick M, Clarke N, Strawbridge M, Yeadon M. Inhaled muscarinic antagonists for COPD--does an anti-inflammatory mechanism really play a role? Curr Opin Pharmacol. 2009;9(3):250-5. http://dx.doi.org/10.1016/j.coph.2009.02.003 33. Wechsler ME, Lehman E, Lazarus SC, Lemanske RF Jr, Boushey HA, Deykin A, et al. beta-Adrenergic receptor polymorphisms and

response to salmeterol. Am J Respir Crit Care Med. 2006;173(5):51926. http://dx.doi.org/10.1164/rccm.200509-1519OC 34. Umeda N, Yoshikawa T, Kanazawa H, Hirata K, Fujimoto S. Association of beta2-adrenoreceptor genotypes with bronchodilatory effect of tiotropium in COPD. Respirology. 2008;13(3):346-52. http:// dx.doi.org/10.1111/j.1440-1843.2008.01259.x 35. Wise RA, Anzueto A, Cotton D, Dahl R, Devins T, Disse B, et al. Tiotropium Respimat inhaler and the risk of death in COPD. N Engl J Med. 2013;369(16):1491-501. http://dx.doi.org/10.1056/ NEJMoa1303342 36. van Noord JA, Cornelissen PJ, Aumann JL, Platz J, Mueller A, Fogarty C. The efficacy of tiotropium administered via Respimat Soft Mist Inhaler or HandiHaler in COPD patients. Respir Med. 2009;103(1):229. http://dx.doi.org/10.1016/j.rmed.2008.10.002

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