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- Calcium cannot be administered along with sodium bicarbonate because calcium will precipitate out SODIUM BICARBONATE : NaHCO3 is a systemic alkalinizing agent. It increases plasma bicarbonate, buffers excess hydrogen ion concentration and raises blood pH, there by reversing the clinical manifestations of acidosis.

Also be used to replenish electrolyte imbalance as a it adjacent for fevers diarrhea where the loss of bicarbonate can be significant.

Pharmacology Sodium bicarbonate is a felt which on reaction with acid will raise the pH by lowering the concentration of hydrogen ion.

NaHCO3 + HCl = CO2 + NaCl + H2O Thus NaHCO3 is used as an antacid in stomach or as an agent to increase the pH of urine or whole body.

Indications : 1) Management of acidosis in cardiac arrest.

2) Management of metabolic acidosis in a) fever send disease b) uncontrolled diabetes c) circulatory in sufficiency from shock or dehydration 3) Alkalinization of urine.

Contraindications 1) In hypoventilatory states 2) Metabolic and / or respiratory alkalosis.

3) Hypocalcemia 35