Congenital anomalies/Dental implant courses by Indian dental academy

morphogenetic process. Fibroblast growth factor has bear shown to alter stalk elongation and epidermal growth factor (EGF) regulater branching.

The FGF and EGF combination results in morphology similar to in vivo studies. ECM molecules regulate presentation and the distribution of growth factors to epithelium at appropriate time during in vivo. There for, the ECM in concern with specific growth factors appears to regulate the complex processes involved in branching morphogenesis.

Cyto differentiation is believed as pre-programmed development occurring in early stages of morphogenesis. A period of in situ epithelial – mesenchymal contact is required for cyto differentiation. After this contact has taken place. Exocrine cell differentiation occurs without continued presence of mesenchyme. There fore it appears there is a partial coupling of morphogenesis and cyto differentiation. Full differentiation of secretory components is apparent at birth, but is complete until the onset of a solid diet and the presence of masticatory stimuli.

This post natal development process includes the maturations of stimulus – secretion coupling that links secretagogue – membrane receptors to signal transudation pathways within the cell and control acinar cell secretion and establishment of neural connections from autonomic nervous system, the primary regulator of salivary gland function.

Saliva formation : ionic transport : Saliva is formed in 2 stage.

First stage – is production by acinar cells.

Second stage – is the ducts that change isotonic solution to the hypotonic solution.

Different systems involved are 1) Na+ K+ - ATpase 2) Na+ K+ Cl- co-trans port system.

3) Bicarbonate secretions – by Na+ / H+ exchanger.

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