Chemical mediators/ dental implant courses by Indian dental academy

• When osteoblast disperse from bony surfaces, in response to PTH, an exposed osteoid – mineralised run away provides osteoclasts with an oppurtunity to attach.

• Attachment involves surface adhesion molecules (integrins) & proteins.

• Osteopontin , a sialophosphoprotein, secures osteoclast docking to bone through an arginine – glycine aspartic acid motif. www.indiandentalacademy.com