IHR Magazine - Winter 2020/2021

Volume 21 – Issue 2 – 2021

PUBLICATIONS M AIL 42709013 | 920 YONGE ST, SUITE 608 | TORONTO ONTARIO, M4W 3C7 | $6

Trends 2021 Plant Based

Retailer’s Note WWW.IHRMAGAZINE.COM

WINTER ISSUE 2020/2021

Jason Wilhelm, Finlandia BC

Artisanally crafted without losing a microelement of the Earth’s goodness and purity.

REGENERATE, AMPLIFY, ENERGIZE YOUR BODY. Highest Grade Organic Fermented Plant Protein.

I am esä Whatever Your Journey

esaorganic

esaorganic

esaorganic.com

esaorganic

CONTENTS PUBLISER’S LETTER Your e-Commerce Checklist EDITORIAL BOARD Our contributors in this issue

NEW PRODUCTS What is new in the industry?

TRENDING The power of Vitamin D

6 7 24

PLANT-BASED NEWS Business Booms with Seafood

36

CORNER RETAIL Finlandia with Jason Wilhelm

10

18 40

INTERVIEW A fireside chat with Aaron Skelton

Less is more.

More isn’t always better. When it comes to probiotics, the potency and stability of the strains are what count the most. That’s true of our entire line of PURICA Probiotic, featuring four different powerful probiotic blends to help support your cardiovascular and digestive systems, immunity and overall health.

Have Nature and Science on Your Side.

For everything you need to know about our 1,000-plus clinical strains, scan your smart phone camera here or go to

purica.com/probiotic

Nature. Science. You.

‫נס״ ד‬ PUBLISHER’S LETTER

YOUR E-COMMERCE CHECKLIST Olivier Felicio

Publisher/Editor-in-Chief

The pandemic has propelled Ecommerce further forward at a record rate. In 2020, consumers spent over $861 billion online with U.S. retailers, a 44% increase from 2019. Globally, the eCommerce industry will reach $4.9 trillion this year. eCommerce generates 10% of all retail sales, with an anticipated 15% year-on-year growth rate.

ISSN 1197 - 1495 | VOLUME 21 ISSUE 2

FOUNDER & THOUGHTSMITH

Olivier Felicio ART DIRECTOR // DESIGN

Marcelo Ramos COSTUMER SERVICE

Navnidhi Joshi

6 / THE HUB - IHR / WINTER ISSUE 2020-2021

Estimates show that there are more than 24 million eCommerce websites. There is a lot of competition, However, with the right tactics and a strong growth strategy in place, you can bring high-quality traffic to your online store, converting new visitors into repeat customers and achieving eCommerce success.

Your Checklist: 1. Run Campaigns Using The RGM Group platform 2. Build Your Brand Awareness 3. Build Your Email List and Stay in Touch 4. Optimize for Mobile 5. Collect Reviews and Feedback 6. Create Social Media Campaigns 7. Market Most Popular Products 8. Retarget Lost Sales 9. Run Promotions 10. Improve Conversion Rate by A/B Testing 11. Provide Excellent Customer Service 12. Grow Using Affiliate Marketing 13. Establish Your Target Audience 14. Offer Complementary Products 15. Market to All Stages of the Funnel 16. Work with Influencers 17. Ship Globally

❱ FIND US ON

Published by Rive Gauche Media Inc. Canada Post Canadian Publications Mail 42709013 The publisher does not assume any responsibility for the contents of any advertisement and any and all representations or warranties made in such advertising are those of the advertiser and not of the publisher. The publisher is not liable to any advertiser for any misprints in advertising not the fault of the publisher and in such an event the limit of the publisher’s liability shall not exceed the amount of the publisher’s charge for such advertising. No portion of this publication may be reproduced, in all or part, without the express written permission of the publisher. All rights reserved. ©Copyright 2019 Rive Gauche Media Inc. ihr magazine is pleased to review unsolicited submissions for editorial consideration under the following conditions: all material submitted for editorial consideration (photographs, illustrations, written text in electronic or hard copy format) may be used by ihr Media Inc. and their affiliates for editorial purposes in any media (whether printed, electronic, internet, disc, etc.) without the consent of, or the payment of compensation to, the party providing such material. Please direct submissions to the Editor, IHR magazine.

CONTRIBUTORS

Denis Courchesne, Daniel Dereser, Franco Cavalari, David Foreman, Mike Hannalah and Lewis Retik.

ADVERTISING INFORMATION PUBLISHER OLIVIER FELICIO – Toronto Office tel: 416.203.7900 x 6107 / email: olivier@thergmgroup.net 608, 920 Yonge Street, Toronto, ON M4W 3C7

INTERNATIONAL SALES INQUIRIES MEHER VESAVEVALA tel: +91 9821136069 / mehernavaz@hotmail.com PURVAZE BUXY tel: +91 9820129492 / purvaze@gmail.com

SUBSCRIPTION RATES Canada $50 (gst included) for nine issues (one year) USA $60 CHANGE OF ADDRESS email: circulation@thergmgroup.net telephone: 416-203-7900 fax: 416-703-6392 or send your cover label and new address to Integrated Health c/o IHR Magazine 920 Yonge Street, Suite 608 Toronto, ON Canada M4W 3C7

EITORIAL BOARD

EDITORIAL BOARD

DENIS COURCHESNE

DANIEL DERESER

FRANCO CAVALARI

Denis Courchesne has a solid background in sales and marketing working for companies such as Mosaic, Evian, Cadbury Adams, Bioforce Canada and Purity Life Health Products. He is president of Quebec Contact Inc., a consultancy firm dedicated to helping clients successfully develop and grow business in the Quebec market. After evolving and advancing his knowledge working in the natural product industry for over 17 years, Denis shares his experience and observations of the trade in Quebec with our readers.

Daniel Dereser, a Doctor of Pharmacy in France, received his degree from Université Aix-Marseille II in 2003 and a training certificate in clinical homeopathy for pharmacists through the Center for Education and Development of Homeopathy (CEDH). Before becoming the CEO of Boiron Canada in 2015, Dereser held the position of director of medical development for Boiron Canada and Boiron U.S.A. He also serves on the board of directors of the Canadian Homeopathic Pharmaceutical Association (CHPA).

Franco Cavaleri completed his BSc with a major in Human Nutrition from the University of British Columbia. He is currently in the last phase of postgraduate doctoral study (current status PhD candidate) at the Faculty of Medicine’s Experimental Medicine Program. Research interest and focus on nutraceutical pharmacology in the context of the pathology of inflammation and inflammatory disease Faculty of Medicine’s Experimental Medicine Program.

DAVID FOREMAN

MIKE HANNALAH

LEWIS RETIK

David Foreman RPh, is a pharmacist, author and media personality known to consumers nationwide as, “The Herbal Pharmacist.”

Foreman is a graduate of the University of South Carolina College of Pharmacy, currently serves on Organic & Natural Health Association’s Scientific Advisory Board, and is author of 4 Pillars of Health: Heart Disease.

With experience in both the professional and regulatory sectors of pharmacy, Mike Hannalah holds a comprehensive knowledge and understanding of the unique needs, challenges and opportunities of pharmacists in Ontario. Currently, he is the director of Smith’s Pharmacy in Toronto, and is a council member of District M at the Ontario College of Pharmacists.

Lewis Retik is the leader of the Advertising & Product Regulatory group and co-leader of the Food & Beverage group at Gowling WLG. As a partner in Gowling WLG’s Ottawa office, he practices primarily in the area of regulatory and commercial law. Lewis’ practice focuses on regulated products, including product distribution, manufacturing, advertising, packaging and labelling, and regulatory licensing.

7 / THE HUB - IHR / WINTER ISSUE 2020-2021

The purpose of our editorial board is to help guide the direction of the publication in a manner that a) improves its quality and rigor, b) exerts a positive impact on patient outcomes, c) contributes to knowledge of integrative health-care, and d) showcases evolving trends in the health-care industry. We believe that our unique blend of readers dictate the tone of our magazine, which allows us to provide you with the most accurate, up-to-date, and essential information relevant to your business. Our editorial committee is comprised of thought provokers who have shaped the industry and whose experience is vital in providing you with the tools to succeed.

THE ONLY COMPLETE VITAMIN D ON THE MARKET Vegan & Plant-Based

Kosher

GMP

NO GMO

Organic

no flavour added

USDA Organic

Gluten Free

no preservative added

esa_organic

esaorganic

esaorganic.com

All benefits in one drop of health: Strongest Vitamin D on the market; Marketing support; Low minimum order; Made in Canada; Great margin.

Artisanally crafted without losing a microelement of the Earth’s goodness and purity.

NEW PRODUCTS

Find your calm with Sisu Magnesium Relaxation Blend. Featuring magnesium bisglycinate, along with GABA and L-Theanine to temporarily promote a more calm, relaxed state without any sedative effects. Available in delicious Raspberry-Lemonade and NEW Tart Cherry and Honey Grapefruit. SRP: $32.99

SLEEP& STRESS

Sisu

ROSE DETOX MASK AND ROSE BEAUTY OIL Maple Organics 1. Helps to minimize and detox pores, deeply cleanse the skin of toxins and impurities. Organic Oats, Kaolin Earth Clay, Bentonite Earth Clay, Organic Turmeric, Organic Rose Petals, Activated Charcoal. SRP: $25.00 2. Helps improve skin’s density and surface with a high amount of rare palmitoleic acid (omega 7) for nourishing & protecting the skin. It also contains palmitic acid, stearic acid, oleic acid, alpha-linolenic acid and linoleic acid. Our natural orange hue is due to the carotenoids which provide radiance and glow, beta-carotene which repairs and prevents premature ageing and lycopene of cold-pressed sea buckthorn oil which helps prevent breakouts and inflammation. Our special blend of Jojoba and Grapeseed oil contains moisturizing omega 3, 6, 7 & 9 fatty acids that help to protect the skin from ageing free radicals which can cause discolouration. SRP: $75.00

DANDIES 10 / THE HUB - IHR / WINTER ISSUE 2020-2021

MARSHMALLOW Chicago Vegan Foods

Offering a much-needed upgrade to traditional marshmallows, these plant-based and vegan treats are made with high-quality, clean ingredients like real vanilla and vegan cane sugar and contain no artificial flavours or colours, no corn syrup, no gelatin, and no gluten. Light, fluffy, and guilt-free addition to a cozy, hot cocoa spread, they’re also kosher, Non-GMO Project Verified, and free of the common allergens wheat, dairy, eggs, corn, peanuts and tree nuts. So break out some fun little bowls, fill them up with your favourite fixings, and celebrate the final months of winter with a sweet sipping experience.

Dandies Marshmallows are available in mini and roasting sizes at select conventional and natural grocers across Canada for an SRP of $5.99 CAN per 283g package.

NEW PRODUCTS

CLINICALLY

ADVANCED HAIR, SKIN AND NAILS VEG CAPSULES NOW FOODS • Helps to maintain healthy hair, nails, skin • Maintains mucous membranes • With clinically tested Cynatine® • Enhanced with Vitamins, minerals and aminos • Comprehensive formula featuring as total of 21 supporting nutrients • Contains Hyaluronic Acid, MSM, and L-Proline NOW® Solutions Clinically Advanced Hair, Skin & Nails nurtures hair, skin, and nails from the inside. It features Cynatine® HNS a revolutionary patented and bioavailable form of solubilized keratin that can help maintain full, lustrous hair and nails that are strong and flexible, and help skin retain its youthful moisture and elasticity, plus battle signs of aging associated with free radicals. With 20 other critical vitamins, minerals, amino acids including MSM, L-Proline, and Hyaluronic acid, this formula has all the necessary nutrients for the support and maintenance of the skin’s healthy and youthful appearance. SRP is $54.98

PROBIOTICS PURICA is delighted to announce an exclusive new collaboration with Kaneka — a global leader in probiotics — to deliver to Canadians the health benefits of more than 1,000 different, wild-type strains strategically sourced from rural areas isolated from modern lifestyle and amenities. Kaneka’s grant of Canadian exclusivity covers the specialty, health food segment for the following products: Floradapt Digest, Intensive GI, Cardio and Mature Immune Defense formulations.

11 / THE HUB - IHR / WINTER ISSUE 2020-2021

Purica

Leader In Pharmacy Nutrition

Designed for: • Most potent VITAMIN D/drop available • Immune (lung) protecting qualities • Maintaining healthy bones & teeth • Enhance absorption & utilization of important minerals including calcium & phosphorus

1111 West Broadway, Vancouver | 604.733.5323 1.800.363.4372 (toll free) | finlandiahealthcentre.com

CALL US FOR A FREE CONSULTATION!

NEW PRODUCTS

QUIETUDE Boiron Boiron’s Quietude is a new homeopathic medicine for the relief of stress and minor sleeping disorders, such as restlessness, difficulty falling asleep, nocturnal awakening, occasional sleeplessness. Quietude is made of 100% naturally-sourced medicinal ingredients and does not cause addiction or drowsiness during the day.

It is available in a 90 tablets format, at an SRP of $16.99.

LIPCANDY BALM CANE Nova Scotia Fisherman

Limited edition while supplies last - Premium, all natural moisture and lip protection with a subtle, refreshing hint of natural peppermint, true Candy Cane flavour from Canada. Naturally sealing in moisture to protect against nature’s elements, at sea or on land. Each balm is created using 100% natural ingredients and contains 93% organic materials.

TORTILLA CHIPS Let There Be Hemp The Original SuperFood is back!

Let There Be Hemp is the better-for-you snack company where all our products are made from protein-packed, super-crunchy, whole hemp seeds. Delicious, satisfying, and nutritious.

MSRP: $4.99 It’s better than ever!

13 / THE HUB - IHR / WINTER ISSUE 2020-2021

GRAIN-FREE

NEW PRODUCTS

NAPPY

CHANGE CREAM Le Petit Prince

Formulated to preserve the most delicate skin. The Nappy Change Moisturizing Cream is indicated to protect the moisture barrier of the most sensitive skin. The presence of titanium dioxide creates a natural protective barrier able to counteract the e ects of moisture on the child’s skin, inside the diaper.

SKIN PROTECTIVE WASH

“Cleanses and protects babies’ skin from their firt day of life.

The Skin-Protective Wash provides cleansing and softness in one step, leaving skin feeling soft and hydrated.”

SUPER FIRM

14 / THE HUB - IHR / WINTER ISSUE 2020-2021

TOFU

Viana

Each Breaded Veggie Entrée provides 23g of premium organic plant based protein. Satisfying chewy texture, crispy breading baked or fried, just heat and serve.

New dedicated Canadian sleeve packaging uses 33% less paper fiber and allows customer to see product. Shelf stable: can be retailed dry, refrigerated or frozen. Imported from our dedicated vegan facility in Germany Ingredients: Tofu* (Water, Soybeans*, nigari [coagulant]), water, wheat protein*, sunflower oil*, breadcrumbs* (wheat flour*, water, sea salt, paprika*, yeast*), sea salt, almond flour*, raw cane sugar*, locust bean gum*, yeast*, spices*. *Certified Organic, Allergens: Contains Soy, Wheat & Almonds.

NEW PRODUCTS

VITAMIN D3 DROPS WITH VITAMIN K2 finlandia Vitamin D3 & K2 (MK7) is a liquid formula designed for maintaining healthy bones and teeth, reducing risk of osteoporosis, and enhancing absorption and utilization of important minerals including calcium and phosphorus.

Vitamins D3 and K2 work synergistically to enhance calcium absorption in bones, with vitamin K2 activating specific proteins for the transportation and binding of calcium from the arteries and blood into the bone matrix. Vitamin K2 as MK7 (methaquinone-7) is more stable and stays in the body longer than other forms of vitamin K. $30.99

VITAMIN D3 DROPS Biomed

Vitamin D3 Drops 15 ml Bone and Immune Health • Strong bones & teeth • Immune function • Osteoporosis Vitamin D3 is needed for the development, growth, and maintenance of strong bones and teeth. It is required for calcium regulation, by promoting absorption of calcium and phosphorus from the small intestine and kidneys to be deposited in the bones for mineralization. Additionally, when vitamin D is combined with calcium intake and regular weight-bearing exercise, it helps reduce the risk of developing osteoporosis.

Vitamin D3 is also required for proper immune function and can modulate both adaptive and innate immune responses. $27.99

NEW PRODUCTS

BIO VITAMIN D3 Pharma Nord

Chosen for the groundbreaking Coronavit Trial The vitamin D supplement that everyone is talking about chosen for the groundbreaking ‘Coronavit’ trial!

• Contain cholecalciferol - a form of vitamin D that is naturally produced in the skin

The trial which will look at the effects of vitamin D supplementation on the immune system and protecting against Covid-19. This is a huge testament to the quality of our vitamin D supplements! You can read more about the trial on our article. With so many vitamin D supplements to choose from, why choose Pharma Nord?

• Easy to swallow ‘pearl’ capusles.

Vitamin D3 is a fantastic nutrient that’s essential for our overall well-being and boasts a number of benefits, including: • Contributing to the support of the immune system. What’s more, studies have shown that vitamin D may stimulate the body’s production of anti-viral and anti-bacterial proteins.

• Dissolved in cold-pressed olive oil for maximum absorption. When it comes to supplements, absorption is key for performance

• Helping to maintain healthy muscles and nerves

• Manufactured to pharmaceutical standards - just like all of our products

• Helping our bodies absorb calcium

• Contributing to the maintenence of normal teeth and bones

17 / THE HUB - IHR / WINTER ISSUE 2020-2021

• Documented bio-availability, proven by science. BioVitamin D3 has been featured in a number of clinical trials which prove their superiority when it comes to a D3 preparation

Benefits of vitamin D3

TRENDING

How

Vitamin D

Could Relieve Vaccine Pressure

Optimism continues to grow with the announcement of several vaccines offering over 90 percent protection against COVID19. However, reports suggest that for a majority of people, the vaccine will not be available until the second quarter of 2021.

Until then, trials continue on the potential support of supplements. Queen Mary University of London recently launched a study into vitamin D, assessing the effectiveness of the supplement in reducing the risk or severity of the virus.

18 / THE HUB - IHR / WINTER ISSUE 2020-2021

The effectiveness of vitamin D is now being recognized by both national and devolved governments in the UK. Some scientific advisers are now suggesting that a national provider of vitamin D could be used to help reduce infections or hospitalizations until the vaccine is ready for widespread administration. However, will vitamin D be used to help ease the burden of viral infections while vaccines are rolled out across the country?

A national deficiency While the NHS recommends that additional vitamin D supplements should be used between October and early March due to limited sunlight hours, in 2020 the public health body has suggested that the vitamins should be used year-round as a consequence of lockdowns and limited outdoor time.

A deficiency in vitamin D is an attributing cause of rickets, especially among children. A study also found that COVID-19 patients are almost twice as likely to be deficient in vitamin D. There is not yet enough evidence that vitamin D can prevent coronavirus. But, with little to no side effects involved in taking the supplement, could its use be a tentative win for public health?

Concurrent trials The quick development of vaccines for COVID-19 has been hailed by medical professionals, the latest Oxford vaccines demonstrate up to 90 percent efficacy. However,

studies continue to explore how vitamin D can help to alleviate symptoms and reduce recovery time.

Vitamin D has anti-inflammatory properties. This means it may provide assistance to the body’s immune response to respiratory illnesses. Lung damage as a result of the coronavirus can an inflammatory cytokine storm. Essentially, an overwhelming inflammation caused by your body’s immune system releasing proteins. The inflammation can cause serious illness or be fatal.

There are suggestions that vitamin D’s anti-inflammatory effects will alleviate this condition.

Meanwhile, Queen Mary University continues its randomized clinical trial. They are testing whether the implementation of a test-and-treat approach which will correct insufficient levels of vitamin D will result in reduced risk or severity of COVID-19 and other acute respiratory infections.

TRENDING

The trial is supported by the pharmaceutical companies, Pharma Nord, and NHS trust charity, Barts Charity. Their support highlights the potential effectiveness of vitamin D against respiratory illnesses, particularly among older generations.

Government support News of vitamin D’s potential effectiveness against the coronavirus has reached UK Parliament. Before implementing the second national lockdown in England, on 2nd November, the Prime Minister was questioned on the specific benefits of the supplement. MP David Davis suggested: “[Vitamin D] could reduce infection rates by half and case death rates by half again.

“The Scottish Government are sending four months’ supply of vitamin D to everybody who shielded in Scotland. Given that it

is low cost and there is no medical downside, will our Government consider the same approach in England?”

Boris Johnson responded that the results were promising: “We are indeed looking at the possible beneficial effects of vitamin D, and I know that we will be updating the House shortly.”

Following this, it was announced that vitamin D supplements will be delivered to more than two million clinically vulnerable people. This includes all care home residents across England. Beginning in December, the supplies are intended to last throughout the winter.

Speculation continues whether this rollout could be extended to more individuals or for a longer period as the government supports more trials into the effectiveness

of vitamin supplementation. Health Secretary Matthew Hancock reiterated optimism surrounding the idea: “I have asked the scientists to look once again at the impact of vitamin D on resistance and immunity.”

Using vitamin D to support the vaccine administering is being made as a clear and achievable objective for governments across the UK. Approved vaccines are expected to be used from December 2020, targeting the most vulnerable first. This includes older people and those with pre-existing medical conditions, before targeting NHS and key workers. However, until this can be implemented for the general public, vitamin D may be of use to help the recovering population.

19 / THE HUB - IHR / WINTER ISSUE 2020-2021

Sources: https://www.nhs.uk/conditions/vitamins-and-minerals/vitamin-d/ https://www.thetimes.co.uk/article/people-hit-hardest-by-virus-more-likely-to-lack-vitamin-d-qht9qt82n?wgu=270525_54264_16063914869073_66c697 96f2&wgexpiry=1614167486&utm_source=planit&utm_medium=affiliate&utm_content=22278 https://www.bbc.co.uk/news/health-55040635 https://knowablemagazine.org/article/health-disease/2020/what-cytokine-storm https://www.qmul.ac.uk/media/news/2020/smd/clinical-trial-to-investigate-whether-vitamin-d-protects-against-covid-19.html https://hansard.parliament.uk/commons/2020-11-02/debates/6AF57346-80F3-491D-AA67-9EF31B9B3B26/Covid-19Update https://economictimes.indiatimes.com/news/international/world-news/uk-plans-vitamin-d-rollout-to-vulnerable-as-covid-19-protection-report/articleshow/79111797.cms?from=mdr

TRENDING

Clinical Review: Effects and Presumed Mechanism of Action of the French Oak Wood Extract Robuvit

by Franziska Weichmann, Fabrice Avaltroni, and Carolina Burki

20 / THE HUB - IHR / WINTER ISSUE 2020-2021

INTRODUCTION Not many plants can provide mankind with food and shelter. Big enough to construct houses, strong enough to build boats resisting ocean travels, and energy-packed to warm up cold winter nights since centuries, the oak tree has historically intermingled with several fundamental aspects of human life. Since antiquity, the oak tree has also granted a more discrete, but direct contribution to human diet. Archetypal European beverages such as wine, sherry, spirits, brandy, whisky, or condiments such as vinegar share oak as the favorite wood type for the barrels, they are slowly matured in a traditional process, which can last up to several decades. During aging, various soluble oak components diffuse into the liquid and, among other properties, enhance the intensity and complexity of its flavors.1–3 Another such property is the longer storage life resulting for wines and spirits. This is presumably the primary reason for the practice of aging beverages in oak wood containers. The use for food, such as miso, soy sauce, kimchi, and sauerkraut, attests a protection from spoilage conferred, in part, by the extractables obtained from oak wood containers. Among the different oak species, one is especially praised among winemakers as yielding the highest quality wines: French oak (Quercus robur L.). Conveying benefits of this esteemed oak to humans led to the introduction of Robuvit standardized French oak wood extract to the market in 2014, manufactured by Horphag Research.

To structure and summarize the numerous health benefits of this dietary supplement, evidenced by clinical trials,5–28 is the main topic of this review. Its composition, bioavailability, and safety aspects will also be discussed, along with plausible mechanisms of action.

COMPOSITION The botanical species used to manufacture Robuvit is Q. robur L. (Linnaeus). It belongs

to the Fagacea family, genus Quercus, and is collected in the Massif Central region in France from forests controlled by French agricultural and forestry authorities. This ensures sustainability and respect of stringent environmental protection guidelines.

Once gathered, the wood plant part (lignum) is extracted using water as the sole solvent. The resulting organoleptic features of Robuvit are a soft characteristic odor and a taste in the woody family notes, more specifically humic, tannic, underwood, and a light beige fine powder appearance.

Robuvit is standardized to contain no less than 40% polyphenols, as measured by the well-established Folin–Ciocalteau total phenolic assay.29 Its polyphenols belong to the ellagitannin class, named after the ellagic acid moiety esterifying every individual of this class. It possesses potent antioxidant and free-radical scavenging properties.30 The ellagitannins determined in Robuvit are the diastereoisomers castalagin and vescalagin (a-hydroxyl aglycone and b-hydroxyl aglycone, respectively), along with grandinin and roburin E. These compounds differ in their glycosylation patterns (bxylose and b-lyxose). The dimeric versions of these structures and signature bioflavonoids specific for Q. robur are roburins A, B, C, and D, also differing in their glycosylation patterns (a-hydroxyl aglycone, b-lyxose, bxylose, and b-hydroxyl aglycone). Other compounds such as castalin, vescalin, and smaller phenolic acids (ellagic acid and gallic acid) are also found in Robuvit.

MECHANISM OF ACTION Robuvit affects cellular mitochondria and ribosomes, improving energy and (muscle) protein synthesis and in addition, it decreases oxidative stress (Fig. 4).9,13,36,37 Mitochondria regeneration Ingested Robuvit polyphenols undergo metabolism by gut microbiota, which generates urolithins A, B,

and C. The Robuvit metabolite urolithin A favorably affects mitochondria for enhanced energy production in a process referred to as mitophagy.36,38 Dysfunctional mitochondria are removed through autophagy, and the turnover of mitochondria is promoted, thus preserving energy metabolism.

The mitophagy process ensures that optimal energy in form of adenosine triphosphate (ATP) is gained from consumed food.36,38 Mitochondria generating ATP might be also subjected to oxidative damage, which progressively affects the ATP energy output. Mitochondrial regeneration, or mitophagy, is accelerated in presence of Robuvit supplementation and in consequence, a higher energy output may be deployed (Fig. 4, upper right part).36,38 In addition to that, a gene expression analysis showed a significant increase in mitochondrial protein nicotinamide adenine dinucleotide (NADH)-dehydrogenase after Robuvit supplementation. This enzyme is directly involved in the electron transport of the respiratory chain to generate ATP and thus improves energy production (Fig. 4, upper left part).

CLINICAL EFFECTS OF ROBUVIT The reported improved mitochondria regeneration, enhanced ribosomal biogenesis, increased muscle mass, and the elevated antioxidant capacity caused by urolithins give a rational basis for the results of clinical trials with Robuvit, which was shown to accelerate overall energy.8,22–24 Decreased fatigue symptoms22,23 and better sleep,16,23,27 faster recovery after disease7,10–12,17,19,26 or surgery,5,14 improved mood,8,16,27 enhanced erectile function,22,24 reinforced antioxidant defense mechanisms in periods of stress,18 or enhanced muscle mass gain after intense exercise6 are the effects that have been described in diverse clinical studies. In addition, an ameliorating effect on minimal lymphedema could be observed after supplementation with Robuvit

For Respiratory Health

Inflammatory Response

Hay Fever

Seasonal Allergies

With more than 160+ clinical trials and 450+ scientific publications, Pycnogenol® is one of the most researched and safest ingredients in the world.

follow us on…

www.pycnogenol.com

*For a complete list of scientific research and further information visit our website at www.pycnogenol.com. Pycnogenol®, French maritime pine bark extract, is a registered trademark of Horphag Research, Ltd and its applications are protected by U.S. patents and other international patents. ©2021 Horphag Research USA, Inc. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

TRENDING

in several studies.20,21,28 However, the mechanism of action for this effect is not yet fully elucidated. The antioxidative and anti-inflammatory action of Robuvit13,24 could have beneficial impacts in this context, as oxidative stress, enhanced formation of reactive oxygen species and accelerated lipid peroxidation processes are present in chronic lymphedematous tissue.

22 / THE HUB - IHR / WINTER ISSUE 2020-2021

GREATER ENDURANCE IN SPORTS Robuvit improves triathlon performance.

The contribution of Robuvit on physical expenditure during sport activities was investigated in a controlled trial with 54 recreational sports people of both genders, aged 30–40 years, performing in a triathlon.

One group of 27 participants supplemented with Robuvit 300 mg daily, another 27 comparative individuals were assigned to the control group.

Before comparative performances, both groups trained repeatedly together.

A significant performance increase after

2 weeks training was identified in subjects with Robuvit supplementation, compared to the corresponding control group, who presented with performance increase as well due to training (Fig. 8). In addition, this study evaluated the postperformance cramps a day after the triathlon and localized the pain of participants by means of a visual analog rating scale. Both muscle pain and cramping were described to be significantly lower in the Robuvit supplemented group than in the control group. An interesting observation is that lactate dehydrogenase and

unconjugated bilirubin were significantly increased after performance in the control group, while the Robuvit supplemented group presented with no significant alterations of blood hemolysis markers. These observed effects could be explained by the accelerated mitophagy and the increase in muscle mass. Being facilitated by Robuvit, these mechanisms are suggested to represent the basic contributions for greater physical expenditure in sport activities.

PLANT-BASED NEWS

Growth

spurt:

Business Booms for Plant-Based Seafood Alternative

I 24 / THE HUB - IHR / WINTER ISSUE 2020-2021

t’s a good time to be a U.S. plant-based food producer, according to new data released by the Plant Based Foods Association (PBFA) and the Good Food Institute (GFI).

The research, which was commissioned in 2019 from wellness-focused data technology company SPINS, shows that the plant-based food category erupted by 31 percent over the past two years into a USD 4.5 billion (EUR 4.01 billion) industry at the national retail level, with 11 percent of that growth occurring just last year alone. Meanwhile, the total U.S. retail food market grew by 2 percent in dollar sales during that same period – indicating to PBFA and GFI “that plant-based foods are a key driver of growth for retailers nationwide.”

PLANT-BASED NEWS

“We are now at the tipping-point with the rapid expansion of plant-based foods across the entire store, so it is critical for retailers to continue to respond to this demand by offering more variety and maximizing shelf space to further grow total store sales.”

While plant-based milk products dominate the sector, plant-based meat and protein alternatives, including seafood-inspired options,

“When you dial into the younger generation, it’s really much more about their concerns for the environment.”

are contributing to the category’s growth consistently and in innovative ways. The plant-based meat and seafood category, on its own, is worth more than USD 800 million (EUR 715 million), SPINS researchers found, with sales up by 10 percent in the last year.

Currently, plant-based meats account for 2 percent of retail packaged meat sales, with efrigerated plant-based meat “driving category growth with sales up an impressive 37 percent,” according to the SPINS figures. (Note: Plantbased seafood alternatives were counted with plant-based meat alternatives for the sake of the study).

Who is to thank for this significant expansion? Health-conscious consumers, especially those counted among the younger generations, said Michele Simon, PBFA’s executive director.

“Health was pointed to as the number-one driver for why consumers are interested in shifting away, particularly from meat and protein animal products, towards plant-based options in general,” Simon said.

“The fact that it tastes good” is also a primary motivating factor for consumers as far as plantbased products are concerned, Simon added.

“Taste is always high up there as a default,” she said. Jen Lamy, GFI’s sustainable seafood initiative manager, agreed.

“Regardless of what people tell pollsters, studies of what people actually choose to eat (“revealed preference”) consistently show that

25 / THE HUB - IHR / WINTER ISSUE 2020-2021

“Plant-based foods are a growth engine, significantly outpacing overall grocery sales,” said PBFA Senior Director of Retail Partnerships Julie Emmett, in a press release announcing the SPINS findings.

PLANT-BASED NEWS

taste, price, and convenience determine what most people eat,” Lamy said. “Successful plant-based products are appealing to consumers on those attributes more than ever. These products are also appealing to meat-eaters looking to reduce their meat consumption. In fact, Beyond Meat found that 93 percent of the consumers buying the Beyond Burger also had conventional meat in their carts.”

Animal welfare also tends to play a role in guiding many consumers toward the plant-based alternative food market, Simon said. However, particularly when it comes to younger generations, including millennials and Generation Z, a spotlight is being shone on environmentalism as well, as these consumers are “particularly interested in where their food comes from,” Simon said.

“When you dial into the younger generation, it’s really much more about their concerns for the environment,” she said.

Appealing to younger demographics is of the utmost importance to plant-based food producers of all types, according to PBFA and Simon.

PBFA itself – whose membership network includes plant-based seafood alternative providers such as Good Catch, Ocean Hugger Foods, and Fry Family Foods – has been attempting to do just that with its Power Plant campaign, a first-of-its-kind grab-n-go concept offering “a turn-key solution to meet the high demand for plant-based foods on college campuses, in retail and foodservice retail spaces, airports, hospitals, and other destinations across the United States,” the plant-based foods promotional organization wrote on its website.

“While still relatively small compared to other plant-based proteins, the sector is growing, with new companies expanding into the shelf-stable (such as Good Catch plant-based shelf-stable tuna) and fresh (such as Ocean Hugger plant-based raw sushi products) seafood markets,” she said.

If the news cycle over the past few years is any indication, more plant-based seafood alternative developers are cropping up to help put the segment on the map. The aforementioned Good Catch burst onto the scene in 2018 when it secured USD 8.7 million (EUR 7.5 million) in funding to start distributing its plant-based tuna pouches and other products.

“The relentless and indiscriminate killing of marine life is devastating ocean ecosystems,”

Small segment, big opportunity Although the plant-based seafood alternatives segment is small, both Simon and Lamy said it’s being viewed as an area of tremendous opportunity.

26 / THE HUB - IHR / WINTER ISSUE 2020-2021

“Plant-based seafood is a small, but growing segment of the overall market,” Lamy said. “While plant-based beef and chicken products are relatively common, categories like fish and shellfish are underrepresented in the plant-based market. While retailers carry an average of 41 plant-based milk products, they carry an average of 24 plant-based meat and seafood products. Plant-based fish and shellfish present a massive market opportunity, especially with growing unmet demand for seafood globally.”

About USD 9.4 million (EUR 8.4 million), or 1.2 percent, of total plant-based meat dollar sales come from plant-based seafood alternatives, according to Lamy, and around 95 percent of plant-based seafood alternative sales are achieved via frozen products.

seafood. on e k a t h s e fr A New Wave Foods – racts t hat deliver t hat xt all-natural plant e imp taste. hr same traditional s

PLANT-BASED NEWS

“The relentless and indiscriminate killing of marine life is devastating ocean ecosystems,” said Good Catch cofounders and co-CEOs Chris Kerr and Eric Schnell in a joint statement in April 2018. “The only truly sustainable seafood is seafood that allows fish to remain in the ocean. It is abundantly clear that we need a new approach to seafood.”

The Newtown, Pennsylvania-based company offers imitation seafood products made from beans: about 40 percent pea, with the rest being soy, chickpea, lentil, fava, and navy. The special ingredient that differentiates the products from a run-of-the-mill soy burger is sea algae oil, which contains omega-3 fatty acids. Good Catch’s imitation tuna packets come in three flavors: Mediterranean, Oil & Herbs, and Naked in Water. The firm has also created other bean-based products that act as analogs for crab cakes, fish sliders, and burgers.

There is also AFT Holdings, a diversified holding company and the owner of All About Healthy Foods Holdings and its subsidiary Atlantic Natural Foods (ANF), which produces vegan seafood alternative products, including the Loma Linda brand of TUNO products. Marketed as a “shelf-stable” vegan tuna line, the brand is sold by retail giant Walmart across the United States as of March 2019. A spokesperson for ANF confirmed to SeafoodSource in March that 1,100 Walmart stores are carrying the line, which includes Sriracha, Lemon Pepper, and Spring Water varieties in easy-to-open five-ounce cans. TUNO also sells three-ounce pouches in three flavors: Sesame Ginger, Thai Sweet Chili, and Lemon Pepper. The cans and pouches retail for a suggested USD 1.49 (EUR 1.32) to USD 1.99 (EUR 1.77) each.

27 / THE HUB - IHR / WINTER ISSUE 2020-2021

New York City, New York-based Ocean Hugger Foods, another seafood analog developer, has also seen its share of investment, having completed its third early-stage venture capital funding round in January 2019, netting USD 2.88 million (EUR 2.57 million). That doesn’t include the additional USD 250,000 (EUR 222,800) the business received in March 2019 from Kale United AB, a Swedish investment firm focused on plant-based businesses. The company’s main product, “Ahimi,” is made from tomato, soy sauce, water, sugar, and sesame oil, and is meant to resemble ahi tuna.

Leader in Professional Supplements

Bone & Immune Health: Strong bones & teeth Immune function Osteoporosis Muscle weakness Vitamin D deficiency

biomedicine.com

1.800.665.8308

PLANT-BASED NEWS

“If nobody raises their voice about it, we might end up in a similar situation as milk did a few years back when soy milk and almond milk were introduced, claiming a part of the milk category and even claiming a part of the milk cooler,”

Terms and conditions Egil Ove Sundheim, the U.S. director of the Norwegian Seafood Council (NSC) – which has been working directly with American consumers in recent years, to understand what drives and deters modern seafood purchasing – declared earlier this year that “origin matters for the end-consumers.” As such, it worried him how incoming plant-based seafood alternative developers could be creating undue confusion with the words they used to market their products.

“If nobody raises their voice about it, we might end up in a similar situation as milk did a few years back when soy milk and almond milk were introduced, claiming a part of the milk category and even claiming a part of the milk cooler,” he added.

PBFA’s Simon confirmed that issues surrounding the labeling of plant-based seafood alternatives have indeed come up for the organization and its seafood-inspired members.

“One thing that has come up [with plant-based seafood alternatives] is the labeling issue,” Simon said. “We work with our members closely to ensure that they are using proper qualifiers and are being clear. But we are already seeing some pushback from the fish industry, similar to what we’ve seen from the milk and meat industries.”

According to Simon, whether it’s labeling plant-based seafood alternatives or knowing how to promote them competitively, much of the segment remains unchartered territory.

“For meat, the health proposition is clearer – red meat and processed meats, in particular, have been identified as causing diseases and not being good for you in certain quantities. With seafood, the issue is less about health… and more about the environmental impact and overfishing, and so forth,” she said.

29 / THE HUB - IHR / WINTER ISSUE 2020-2021

“We know origin matters – that’s our starting point,” he said. “And that’s why I’m also a little concerned about some vegan/vegetarian products now coming onto market that are labeled as ‘salmon’ or ‘tuna’ or… ‘finless fish.’ I think the industry will have to watch out for what’s going on right now because the definition of salmon, the definition of tuna, is being challenged.” Requirements set forth by the U.S. Food and Drug Administration determine “what a product should be to be called salmon or to be called tuna, and these products do not fulfill those requirements,” Sundheim said. “I think that we [as an industry] have to be aware that this is going on. We have products now using our terminology…that are defined by the FDA not to be what they’re claiming to be. We need, as an industry, to raise our voice.”

PLANT-BASED NEWS

Plant-based diets and incident metabolic syndrome: Results from a South Korean prospective cohort study Hyunju Kim Kyueun Lee Casey M. Rebholz Jihye Kim Source: POS Medicine

Prior studies have shown that plant-based diets are associated with a lower risk of cardiovascular risk factors and incident cardiovascular disease, but risks differed by the quality of plant-based diets. No prospective studies have evaluated the associations between different types of plant-based diets and incident metabolic syndrome (MetS) and components of MetS. Furthermore, limited evidence exists in Asian populations who have habitually consumed a diet rich in plant foods for a long period of time.

Why was this study done?

• Plant-based diets have been associated with lower risk of cardiovascular risk factors and incident cardiovascular disease, but risks have differed by the healthiness of plantbased diets.

• No data are available on how different types of plant-based diets are associated with the risk of metabolic syndrome (MetS), which is strongly predictive of chronic diseases such as type 2 diabetes, cardiovascular disease, and shorter life span.

30 / THE HUB - IHR / WINTER ISSUE 2020-2021

• Limited evidence is available in Asian populations, who have different dietary patterns than Western populations.

What did the researchers do and find?

• We followed 5,646 South Korean middle-aged and older adults who provided data on their usual dietary intake, medical history, health behaviours, anthropometrics, blood samples for laboratory analyses, and diagnosis of health outcomes for 8 years (maximum of 14 years).

• South Korean adults who consumed diets high in less-healthy plant foods (refined grains, sugars, salty foods) and low in healthy plant foods (whole grains, fruits,

vegetables, nuts, legumes, tea and coffee) and animal foods (animal fat, dairy, eggs, fish/seafood, meat, miscellaneous animal foods) had 50% higher risk of developing MetS. • Such less-healthy plant-based diets were associated with 4 out of 5 components of MetS, including abdominal obesity, hypertriglyceridemia, low high-density lipoprotein (HDL), and elevated blood pressure.

What do these findings mean?

• Plant-based diets high in less-healthy plant foods and low in healthy plant foods have an adverse association with MetS. • In an Asian population that has habitually consumed a diet rich in plant foods for a long period of time, it may be important to consider the quality of plant foods for the prevention of MetS. Discussion In a community-based cohort of South Korean adults, greater adherence to lesshealthy plant-based diets (diets high in refined carbohydrates, sugars, and salted vegetables and low in healthy plant foods and animal foods, captured by uPDI) was associated with a higher risk of incident MetS, adjusting for demographic characteristics and lifestyle factors. This association remained significant when BMI was additionally adjusted, and greater adherence to plant-based diets rich in less-healthy plant foods was consistently associated with individual components of MetS (abdominal obesity, hypertriglyceridemia, low HDL-C, elevated blood pressure). Higher adherence to PDI was associated with a lower risk of high fasting glucose. There was no association between other types of plant-based diets (hPDI and pro-vegetarian diet) and MetS. Our findings on uPDI and incident MetS are generally in agreement with prior studies conducted in Western populations. In the Nurses’ Health Study, Nurses’ Health Study 2, and Health Professionals Follow-Up Study, a 1-SD increase in uPDI was associated with greater weight gain and higher risk of incident type 2 diabetes [15]. In the Atherosclerosis Risk in Communities (ARIC) Study, a

PLANT-BASED NEWS

did not show an association with this MetS component. This finding is consistent with a recent meta-analysis that found that greater adherence to plant-based diets, such as PDI, are associated with lower risk of type 2 diabetes [44]. We may not have found associations with other plant-based diet indices because PDI appeared to have the greatest difference in intake of dietary fiber across quintiles (1.3 g/1,000 kcal) compared with other plant-based diet indices. Such small differences underscore that dietary patterns captured with plant-based diet indices in our analytic study population may be slightly different from what was captured in Western populations, considering the very high carbohydrate intake and low fat intake among those in quintiles 2–5 of all plant-based diets

The nutrition composition of uPDI may explain how greater adherence to uPDI may be associated with incident MetS. Those in the highest quintile of uPDI consumed higher total energy intake and sodium but lower amounts of fiber, micronutrients, and antioxidants. Fiber plays an important role in carbohydrate metabolism and weight gain, and fiber intake has been associated with lower risk of inflammation and MetS [34–36].

Although we did not have data on added sugars, previous studies have shown that those with the greatest adherence to uPDI had higher added sugar intake [12]. High intake of added sugars can lead to poor glycemic control and lipid metabolism, particularly triglycerides as excess sugars can increase hepatic de novo lipogenesis [37,38]. Lower intake of micronutrients and antioxidants (potassium, vitamin A or C) can play a role in modulating endothelial dysfunction, which can lead to oxidative stress [39]. A prospective study in the US reported that women with

high nutritional risk profiles characterized as having a higher dietary intake of lipids and a lower dietary intake of micronutrients (vitamin A, C, E, folate) had an elevated risk of incident MetS [40]. Excessive intake of sodium can increase blood pressure, thereby elevating the risk of MetS [41,42].

Importantly, these individual nutrients may have had synergistic effects, and our approach utilizing a predefined index allowed us to consider the totality of the diet.

We did not find an association between hPDI, pro-vegetarian diet, and overall MetS or individual components of MetS. Prior studies in Western populations reported that greater adherence to these plant-based diet indices was associated with lower risk of various cardiovascular risk factors and cardiovascular disease [12–15,17]. However, in South Koreans, intake of plant foods is higher and intake of red and processed meat is lower than in Western populations, considering that grains and vegetables are included in every meal [18,43]. It is possible that higher plant food intake in a population that is already consuming a plant-based diet may not elicit clinically significant metabolic responses. In addition, the null associations that we observed with hPDI may be due to a different categorization of foods in the present study, because several less-healthy plant foods could not be separated from healthy plant foods (i.e., fruit juices were added to the “fruits” category).

Greater adherence to PDI was associated with a lower risk of high fasting glucose, whereas other types of plant-based diets

(>70% of total energy from carbohydrate and 9%–11% of total energy from fat) in our study. Thus, further research in populations with similar dietary behaviors as the South Korean population is warranted on whether other types of plant-based diets such as hPDI and a pro-vegetarian diet are associated with lower risk of MetS and high fasting glucose specifically.

31 / THE HUB - IHR / WINTER ISSUE 2020-2021

community-based cohort of generally healthy US adults, those in the highest quintile of uPDI had a higher risk of incident hypertension [12]. However, our findings differed from a study by Spanish university graduates that found that an unhealthy plant-based food pattern developed from their own cohort was not associated with incident obesity [28]. Our results add to these existing studies by showing that consumption of less-healthy plant foods in the framework of overall plant-based diets may be associated with a more proximal risk factor to these cardiovascular risk factors among populations who habitually consume a diet that is rich in plant foods for a long period.

Litis™ NPN 80070540

Used in herbal medicine to help relieve inflammatory conditions of the gastrointestinal tract.

3 3 3 3 3 3 3 3 3

Research product of Alpha Science™ Laboratories Supportive aid in the management of gastric health Modulates gastrointestinal (GI) mucosal immune system Exhibits anti-inflammatory activity Demonstrates anti-microbial activity Promotes regeneration of GI mucosa Stimulates appetite Alleviates symptoms of GI distress Helps restore normal GI health

Litis™ helps relieve inflammatory conditions of the GI tract.

Spleen extract contains a variety of growth factors, which play an important role in the healing process of the intestinal walls.

Alpha Science™ Litis™ contains (per capsule): DGL (Deglycyrrhizinated licorice) ...................................................................................................................... 300 mg Spleen extract (Sus scrofa)(Fraction-23®) ....................................................................................................... 150 mg L-Glutamine .................................................................................................................................................... 100 mg Marshmallow Root (Althaea officinalis) ............................................................................................................ 50 mg Recommended dose: Adults − Take 1 capsule twice per day with food or as directed by your health care practitioner. Take it a few hours before or after taking other medications or natural health products. For faster results, loading dose is 2 capsules twice per day for two weeks.

The acid-resistant capsule protects the content of the Litis™ formula from hydrochloric acid and allows ingredients to be delivered intact to the intenstines.

Litis™ is manufactured under strict GMP standards and contains no preservatives, dairy, corn, wheat or gluten.

AlphaScienceLabs.com • 1-888-299-0318 • 795 Pharamacy Ave., Toronto, ON M1L 3K2 CANADA

Litis™ NPN 80070540

Used in herbal medicine to help relieve inflammatory conditions of the gastrointestinal tract.

Alpha Science™ Litis™ contains (per capsule): DGL (Deglycyrrhizinated licorice) ......................300 mg L-Glutamine ....................................................100 mg Spleen extract (Sus scrofa)(Fraction-23®) .......150 mg Marshmallow Root (Althaea officinalis) ............50 mg Recommended dose: Adults − Take 1 capsule twice per day with food or as directed by your health care practitioner. Take it a few hours before or after taking other medications or natural health products. For faster results, loading dose is 2 capsules twice per day for two weeks.

Acid-resistant capsules deliver our Litis™ formulation by disintegrating in the duodenum for better intestinal absorption.

Litis™ is manufactured under strict GMP standards and contains no preservatives, dairy, corn, wheat or gluten.

✓ Modulates GI immune system ✓ Exhibits anti-inflammatory activity ✓ Promotes regeneration of GI mucosa

✓ Demonstrates anti-microbial activity ✓ Alleviates symptoms of GI distress ✓ Soothes inflamed mucous membranes

Litis™ is an innovative, natural health product developed by Alpha Science™ Laboratories which is designed to support the gastrointestinal (GI) health through supporting the GI mucosal immune system. Litis™ contains spleen-derived bioactive peptides, leukotrienes, platelet-derived growth factors, and cytokines.

These ingredients are known to modulate the immune system, promote regrowth of GI mucosa and act as anti-inflammatories. The spleen-derived factors in combination with L-glutamine and medicinal herbs support and repair the entire GI tract.

The Litis™ formula contains a specific fraction of spleen extract (Fraction-23®), a research product of Alpha Science™ Laboratories. Fraction-23® is a specific combination of key bioactive isolates which includes tuftsin and splenopentin,

✓ Maintains mucosal cell integrity ✓ Helps repair GI tract

platelet-derived growth factors and immune modulators obtained from spleen extract by a proprietary process developed by Alpha Science™ Laboratories.

Fraction-23® has been scientifically evaluated for efficacy using an equine model.

The gastrointestinal system plays a key role in the complex mechanisms of immuneregulation as 70% of the entire immune system is found at this level. Clinically evaluated for efficacy, Fraction-23® has shown to help repair the gastrointestinal mucosa.

Litis™ is indicated for use with gastrointestinal inflammation such as irritable bowels, peptic ulcers, chronic ulcerative colitis, Crohn’s disease and celiac disease.

Litis™ helps to stimulate appetite and reduce symptoms of GI distress. Litis™ is well tolerated and has shown no adverse reactions.

Growth factors production and their principle actions in wound healing include: Growth Factor

Production

Principle action(s) in wound healing

Colony-Stimulating Factors (CSF)

Stromal cells, fibroblasts, endothelial cells, lymphocytes

Granulocyte colony stimulating factor (G-CSF): Stimulates granulocyte proliferation Granulocyte Macrophage Colony Stimulating Factor (GM-CSF): Stimulates granulocyte and macrophage proliferation.

Epidermal Growth Factor (EGF)

Platelets, macrophages

Stimulates fibroblasts to secrete collagenase to degrade the matrix during the remodeling phase. Stimulates keratinocyte and fibroblast proliferation.

Fibroblast Growth Factor (FGF)

Macrophages, mast cells, T-lymphocytes

Promotes angiogenesis, granulation, and epithelialization via endothelial cell, fibroblast, and keratinocyte migration, respectively.

Keratinocyte growth factor (KGF) Fibroblasts

Stimulates keratinocyte migration, differentiation, and proliferation.

Platelet-Derived Growth Factor (PDGF)

Platelets, macrophages, keratinocytes, fibroblasts, and endothelial cells

Attracts macrophages and fibroblasts to zone of injury. Promotes collagen and proteoglycan synthesis.

Transforming Growth Factor (TGF)

Platelets, macrophages, lymphocytes, hepatocytes

TGF-a: Mitogenic and chemotactic for keratinocytes and fibroblasts.

TGF-b1 and TGF-b2: Promotes angiogenesis, up-regulates collagen production and inhibits degradation.

TGF-b3 (antagonist to TGF-b1 and b2): Has been found in high levels in fetal scar-less wound healing and has promoted scar-less healing in adults experimentally when TGF-b1 and TGF-b2 are suppressed.

T-cell growth factor (TCGF), also known as Interleukin-2

Macrophages, keratinocytes, endothelial cells, lymphocytes, fibroblasts, osteoblasts, basophils, mast cells

IL-1: Chemotactic for neutrophils, fibroblasts, and keratinocytes. Activates neutrophils.

IL-4: Activates fibroblast differentiation. Induces collagen and proteoglycan synthesis.

IL-8: Chemotactic for neutrophils and fibroblasts.

Vascular Endothelial Growth Factor (VEGF)

Platelets, macrophages, fibroblasts, Promotes angiogenesis during tissue hypoxia. smooth muscle cells, neutrophils, and keratinocytes

AlphaScienceLabs.com • 1-888-299-0318 • 795 Pharamacy Ave., Toronto, ON M1L 3K2 CANADA

PLANT-BASED NEWS

The novelty of our study comes from the prospective evaluation of the associations between different types of plant-based diets and risk of MetS. Our results expand the understanding of how an unhealthful plant-based diet may be associated with type 2 diabetes and cardiovascular disease by investigating a proximal risk factor for these conditions. Strengths of our study include the use of data from a community-based cohort, validated food frequency questionnaire, repeated dietary assessments, and sufficient follow-up period to ascertain incident MetS. Our data also contribute to the literature with a unique focus on an Asian population.

However, several limitations need to be taken into account. Although we used a food frequency questionnaire validated in South Korean adults, reporting of dietary intake can still be subject to measurement error. We made slight changes to the categorization of foods, because certain less-healthy plant foods and healthy plant foods were asked together. This may have led to an attenuation

of the association between hPDI and incident MetS. Furthermore, there were no data on vegetable oil or olive oil intake in this population, which is likely an important source of dietary fatty acids and could have affected blood lipid levels. Future studies could use more detailed food frequency questionnaires by asking about healthy plant foods and lesshealthy plant foods separately, and assessing vegetable oil intake. Lastly, although we adjusted for important confounders, there may still be residual confounding.

The dietary guidelines for South Koreans have recommended eating a balanced diet, including a variety of foods such as grains, vegetables, fruits, beans, fish, eggs, meat, poultry, and dairy products; consuming less salt-preserved foods; using less salt when preparing foods; and selecting foods lower in salt, sugar, and fat [45]. Our findings on uPDI provide support for these recommendations, considering the strong positive association between this dietary pattern (high in refined grains, sugars, and salty foods) and incident MetS. If

our findings are replicated with different health outcomes or study designs, it may be useful to make a distinction between healthy plant foods and less-healthy plant foods in future dietary guidelines for South Koreans.

In conclusion, in a community-based cohort of South Korean adults, diets high in less-healthy plant foods in the context of a plantbased diet were associated with higher risk of incident MetS, particularly abdominal obesity, hypertriglyceridemia, low HDL-C, and elevated blood pressure. These results highlight the importance of considering the quality of plant foods with regard to more-healthy plant foods versus relatively less-healthy plant foods for the prevention of MetS. Further research confirming the associations between PDI, hPDI, pro-vegetarian diet, and MetS in other ethnic populations with different dietary behaviors is warranted.

At approximately 230,000 square feet, it will be the largest facility and investment of its kind in North America.

34 / THE HUB - IHR / WINTER ISSUE 2020-2021

EU parliament decides the fate of ‘veggie meat’ industry.

In a recent vote, the European Parliament decided not to ban the use of meat-related names for plantbased substitutes, such as ‘veggie burgers’ and ‘soy sausage’. The vote was part of the massive reform of the Common Agricultural Policy and the area that deals with how products can be marketed.

Included in the list of proposed amendments was a request to restrict the use of meat-related terms such as ‘burger’, ‘sausage’ and ‘steak’ for products that actually contain no meat.

European meat and dairy organizations, including Copa-Cogeca (the voice of European farmers and agri-cooperatives), the European Livestock and Meat Trades Union and the International Butchers’ Confederation, among others, argued that using such terms for plantbased products is misleading.

The discussion surrounding the denomination of plant-based meat substitutes is particularly timely given that the new strategy is to urge consumers to move towards a more plant-based diet in order to reduce “the risk of life-threatening diseases and the environmental impact of our food system”.

Parliament divided Members of the European Parliament (MEPs) were divided on the subject. The different sectors were divided as well. The plantbased food industry argues that such a move hinders Europe’s transition towards a healthier and more sustainable food system, one that – under the EU Farm to Fork strategy – calls on consumers to move to a more plant-based diet.

They argue that current labels are not confusing and that consumers buy plant-based products to address concerns related to their health, the environment and animal welfare.

Europe’s farmers and farming associations did not agree. In October, Copa-Cogeca, along with several other farming associations, launched a campaign against the misuse of meat denominations. “The meat denomination debate is not an attack on vegan or vegetarian products,” explained Paul-Henri Lava, senior policy advisor at the poultry processors’ organization AVEC. “We accept and recognize the consumer’s choice to opt for vegan products,” he continued.

“However, what we cannot accept is that vegan and vegetarian products use the reputation and heritage of some meat denominations to sell products which are completely different and

PLANT-BASED NEWS

sorry to say that this is an obvious case of cultural appropriation,” he said. “Certain marketing agencies are using this to deliberately confuse consumers by promoting the view that substituting one product for another has no impact on the nutritional intake. This path may be paved with good intentions, but in the long term, it will open the door to the arrival of other confusing denominations... We are about to create a ‘brave new world’ where marketing is disconnected from the real nature of products, one which blithely amalgamates big business interests and values,” he added.

We know that nationally, some member states have already put forward some initiatives to protect meat sales denomination

Describing plant-based foods Organizations like the World Resources Institute have spent years exploring what language works and what does not when it comes to describing plant-based foods in the US and the UK. Its conclusion is that the way foods are named does indeed significantly influence their uptake. The institute suggested moving away from words like ‘meat-free’, ‘vegan’ and ‘vegetarian’, in favour of a focus on ‘provenance’, ‘flavour’ and ‘look and feel’. An example provided in the final report revealed that changing the name ‘meat-free sausage and mash’ to one of the suggested alternatives had indeed boosted sales.

Using ‘better sausages and mash’, for example, boosted sales by 6.5%. Switching to ‘field-grown sausages and mash’ boosted sales by 51.3%, while opting for ‘Cumberland spiced veggie sausages and mash’ boosted sales by 76.2%. Note that all 3 examples still use the word ‘sausages’ to describe a plant-based, non-meat product. (top image) “The use of ‘meaty’ names on plant-based products makes it easier for consumers to know how to integrate these products in a meal and, as such, they should not be banned,” BEUC concluded. “The denomination of vegetarian and vegan products should neither mislead consumers nor discourage them from buying these products.”

The imitation industry has taken advantage of a European loophole to hijack these powerful common names in its favour and make huge profits from that Cultural appropriation Pekka Pesonen, head of Copa-Cogeca, disagreed: “If the purpose is to promote plantbased products, why should this be done at the expense of tradition and work are done by other product categories?” Lava agreed, saying that meat denominations are deeply rooted in EU cultural heritage. Ham, escalope, fillet, sausage and cordon bleu are all traditional names that have been derived from the hard work of farmers and producers, he said. “Although these products can have different local interpretations depending on the European region, everybody knows what to expect when they buy them,” Lava said. “This is why there has never been a need to protect them.”

Heritage As the marketing of meat alternative products grows, the meat sector believes its common heritage is at stake. “Without protection, tomorrow an escalope could easily be made of carrot, soybean or potato starch, while for many years consumers have always known that it was made of poultry meat,” said Lava. “The imitation industry has taken advantage of a European loophole to hijack these powerful common names in its favour and make huge profits from that.”

Jean-Pierre Fleury, chair of the Copa-Cogeca working party on beef and veal, agreed. “I am

“Of course, we are disappointed with the result of the vote,” said Lava following the announcement, “given that, initially, back in 2019, we knew that the Agriculture Committee supported our amendment. We fail to understand the logic of those MEPs who voted for an amendment to protect milk denominations but rejected our amendment to have the same protections for meat.”

The organization plans to continue its efforts to protect meat denominations. “We know that nationally, some member states have already put forward some initiatives to protect meat sales denomination,” said Lava, pointing to France.

“This shows that our argument is justified.”

In the meantime, Lava suggests that the meat-alternative sector should follow its own path and get creative with new names, as margarine producers once did. They did not hijack the term “butter” to promote the new alternative, he pointed out. “Today the two denominations coexist, and margarine has become a popular alternative to butter,” he said in conclusion.

Source: Pig progress

35 / THE HUB - IHR / WINTER ISSUE 2020-2021

have nothing to do with them in terms of taste, composition and nutritional value.”

Vote disappoints meat sector In late October, MEPs voted 284 in favour of the amendment and 379 against, with 27 abstentions. The MEPs, however, did approve an amendment to further limit the use of dairy-related names for plant-based dairy alternatives such as “cheese substitute” and “yogurtstyle”. EU law has already banned the use of ‘milk’, ‘cheese’ and ‘butter’ on vegan products that do not come from animals. ‘Soy milk’, for instance, is not allowed but ‘soy drink’ is.

CORNER RETAIL

Finlandia, your all-in-one integrated pharmacy

by Dave Gordon

F 36 / THE HUB - IHR / WINTER ISSUE 2020-2021

inlandia’s massive 5,000 sq. ft store at 1111 W Broadway in Vancouver now employs around 50 people.

The store is well set up for online orders and storefront pick-up, and Wilhelm said his customer base is only increasing. “We believe in maintaining as much person-to-person interaction as possible. This is what sets us apart from many other retailers.”

Clients, he added, seek out natural options or alternatives to conventional medicine. “There is definitely a larger interest in and awareness of natural medicine today.”

Besides, diet-conscious customers are making up more of the conversation at Finlandia. “No matter the style of eating, we want to ensure you are getting adequate vitamins and mineral intake.”

“Finlandia still leads in the pack in terms of being ‘integrative.’ We can provide seamless integration of natural supplements, pharmaceutical drugs, and in-betweens.”

CORNER RETAIL

37 / THE HUB - IHR / WINTER ISSUE 2020-2021

“Finlandia is always growing and evolving,” Wilhelm summarized. “We have an expansive health retail store, huge online store, herbal dispensary, and full prescription pharmacy, all in one location.”

CORNER RETAIL

Moreover, he said animal-byproduct consciousness is a growing theme in the products he stocks.

“Most of our products do not contain animal ingredients and would be considered plant-based. The trend is certainly on seeing the vegan claim on more and more products.”

One of the most popular supplements amongst our clientele at Finlandia Pharmacy and Natural Health Centre is Vitamin D. However, according to the company’s General Manager, Desmond Yau, and Chief Operating Officer, Gavin Mah, Vitamin D is also widely misunderstood.

Most Canadians, they said, won’t get enough Vitamin D from the summer months alone.

The Recommended Dietary Allowance, they argued, is insufficient and out of date with current medical thinking.

Getting your fill of Vitamin D from food alone is also pretty hard, they said, unless you eat a massive amount of cod liver oil, canned sockeye salmon, halibut, mackerel, and mushrooms that have been under UV light.

One tip they offered was to take a Vitamin D supplement with something mildly fatty, because of the vitamin’s fat-soluble nature. Beyond the well-known effects, Vitamin D has on increasing healthy bones, it’s also useful to strengthen your immune system, prevent diabetes.

38 / THE HUB - IHR / WINTER ISSUE 2020-2021

It also provides cardiovascular, neurological, and cellular protection.

Everyone’s looking to boost their immune system in the time of COVID, and that’s informed Finlandia’s approach of late. “We’ve pivoted to increase staff and customer education on immune and health-enhancing supplements,” Mah said. And whereas they’ve always been customer-centric, during the pandemic they’ve taken great care to reduce contact-point type shopping, and increase mail-outs, online orders, phone orders, curbside deliveries and car deliveries of supplements and prescriptions.

Whether it’s Vitamin D, magnesium, Vitamin C, probiotics, or digestive enzymes, Yau said choosing the right brand comes down to the customer’s needs.

And looking after a customer’s needs is what an integrated pharmacy is there to do.

CORNER RETAIL

Most people have to go to two separate places for their prescription drugs and their natural health supplements.

Jason Wilhelm says that’s a problem, but with a simple solution.

There are several professional supplements, like DHEA, melatonin, progesterone cream that natural health stores aren’t allowed to carry.

Similarly, a typical pharmacy won’t carry many natural health supplements.

If a naturopathic doctor prescribed their patient progesterone cream and a handful of supplements, they would need to visit both a healthy living store and a pharmacy to fill all their medical needs.

Wilhelm, who used to run a health food store, knew it was necessary to have a future where the two needs were met with one location.

With wide access to information How technology has impacted your business?

Customers have done more research on their own - this can mean they know exactly what they want, or this can mean they get overwhelmed with the information.

The access to information has also pushed us to be constantly keeping up with trends.

Due to technology, our online sales have become a very important part of the business.

In medicine, we see the trend of more telemedicine, AI and RPA, how those new technology fit in a boutique-style pharmacy?

We incorporate as much technology as we can into our pharmacy to ensure our customers get the best experience possible. There are more requests for products based on practitioner recommendations from virtual appointments.

39 / THE HUB - IHR / WINTER ISSUE 2020-2021

Although this trend is emerging, we believe in maintaining as much person-to-person interaction as possible.

This is what sets us apart from many other retailers. We have implemented automation in places to improve our efficiency, but we have also ensured this does not take away from our level of service.

INTERVIEW

In this in-depth interview, we talk to Aaron Skelton, President and CEO at the Canadian Health Food Association (CHFA) who joined the team in September of last year. We wanted to spend some time getting to know him better, understanding his vision for the association, some of the challenges he anticipates along the way and his insights on what the future holds in the post-pandemic world.

40 / THE HUB - IHR / WINTER ISSUE 2020-2021

Tell us a bit more about yourself and your background?

Having been in the industry for over 16 years, including time on both the retailer and supplier side, I try and understand the nuanced challenges felt by each and the need to facilitate the interactions between these two groups.

With experience in strategic planning, team development, retail and manufacture operations, product development and sales planning, I see tremendous potential and opportunity for the future of CHFA and for the shared success of all those within the industry that support it.

A Fireside Chat with Aaron Skelton

I’m excited about these opportunities ahead and when I’m not working out on my bike trainer or chasing my two and four-year-old around, I have been working very closely with the team to carve out a new path and direction for CHFA. We are constantly working to inspire our Members with insights, trends, new products, how-to’s, and more to help drive what’s next. We were born from our natural ability to connect the industry through our events, and our ability to foster lasting relationships and are now creating even more, opportunities for these connections to happen, outside of our traditional live trade shows.

What is your vision for CHFA? It’s continuing to build on all the great foundational work we have done while making sure we are meeting our Members needs by evolving as they evolve given the new realities and new normal we are all facing. This means creating a member-focused service environment within the association that will support their needs while expanding on our current offerings and value.

We will do this while delivering a best in class member experience and making it a priority that our association is reflective of the diversity that exists within our industry.

How are things “different” at CHFA since you have joined?

We’ve always focused on ensuring we support and deliver value to our Members so their business can thrive. For over 50 years

INTERVIEW

Our regulatory affairs and government relations department strives to positively influence government policy, to benefit our industry. In the last five years, we’ve had 208 meetings with MPs, Senators or Parliamentary Staffers and responded to a total of 37 consultations. We continue to build on these strong working relationships meeting face-to-face with decision-makers to address the concerns of our members on an increasing and ongoing basis. I have been part of these meetings and discussions and truly believe our Members’ voices are being heard.

We will continue to amplify these efforts and are broadening our expertise as we expand our focus to food and CBD initiatives, again ensuring our members’ needs are addressed.

We have continued to engage consumers through our Healthier by Nature platform that includes social channels with an extended audience of 211,000 followers. Sharing health and wellness news, promoting our members’ products and the positive impact they have, has been valuable to both consumers and our membership. This year we are expanding these efforts with the launch of our first-ever, virtual consumer show. This a BIG deal and the team has been energized by the value this is creating for our Members. Building from our platform and audience, the Healthier by Nature Expo, taking place March 20, has been created to give our members the opportunity to directly connect with an audience of health and wellness enthusiasts they have been struggling to engage with this past year.

What can Members expect now?

Our role is to foster a successful and vibrant health food industry and to achieve this we really act as the hub and spoke, connecting all the players within this space. We truly represent the entire industry, not just a group within the industry. Whether you’re a supplier, distributor, broker, retailer or manufacture, if there are things you need to be successful, we act

as a conduit connecting you to these resources.

We have endless solutions to different challenges.

Did you get a problem? We’ve got an answer.

We’ve always ‘got a guy’ for that. We’ve earned the right to say we’re the experts, know the experts, and connect our Members with the best.

How are you delivering on these expectations?

Now more than ever our Members are looking to connect and access resources so they can support themselves and navigate in this ever-changing environment. Through the evolving positioning of CHFA, we are facilitating access to these resources. Our members miss the ability to come together, to have meaningful conversations that allow them to support and accelerate the success of their business. We are creating a space for that to happen beyond our live trade shows.

We have developed new membership platforms, which have been designed to give our members even more value by delivering the benefits of our trade shows, all year long. We are keeping Members informed with the latest industry trends, research, insights and training. This includes reports, webinars, live and virtual speakers series’ and a committed Member Care Team.

We help accelerate the growth of business, by providing access to leading industry experts, creating opportunities for mentorship and networking.

We continue to provide a unified voice for the industry in Ottawa, ensuring our Members interests are heard and their business priorities are understood. We have created new ways to connect through our virtual events, giving our Members a platform to come together, network and make new connections during a time when face-to-face meetings are just not possible.

What do you see as the biggest challenge when trying to meet these expectations?

We are not yet known for this. Our biggest challenge is enabling the conversations so that our Members and the broader industry understand that we are more than a trade show organization. We are evolving and driving value and support in new ways. When we are able to connect and have conversations the excitement and support have always been significant. We need to continue to have these conversations and create opportunities to share how we can support our members and hear openly from them on what they need. I always encourage Members to reach out to our Member Care Team directly at membership@chfa.ca.

What changes for CHFA coming out of COVID-19?

We will continue to focus on the opportunities. Building upon what we have started, and not simply reverting back to where and what we were. What you will see from us is the continued build on our foundation and the expansion on what we have developed and the areas we have proved to be very successful. We will also focus on growing in the areas that are most important to our Members as their businesses evolve to meet new consumer demands and behaviours.

Simply put, this means more connections.

More networking. More mentorship. More opportunities to grow your business. A stronger voice for our membership.

Where do consumers fit in all this and how does CHFA facilitate these interactions?

More than ever consumers recognize the benefit of being proactive and maintaining optimum health. At CHFA our vision is Canadians achieving better health, naturally and it is through a partnership with our members that we will be able to achieve this.

As consumers are taking more accountability for their own health, our Members are focused on helping them achieve this, which is why we created the Healthier by Nature Expo. This is our first virtual consumer event that will give our members a platform to connect and engage with consumers in ways that have been very difficult during the past year. It will allow Members to leverage their influencers and ambassadors to create experiences through brand activations that will not only educate but also inspire consumers, creating value for all participants. You can find out more at healthierbynature.ca/expo What’s the final thing you want our readers to know?

We are just getting started! And there is nothing we want more than to connect with you. On April 16 & 17 we are hosting CHFA Connect which we have reimagined to create a ground-breaking, virtual event that is going to bring us all together as a community to inspire creativity and foster collaboration. There’s never been a more important time to engage with buyers, service providers and your peers to strengthen these connections while also forming new relationships and creating new business opportunities for your business. Find out more at chfaconnect.ca

41 / THE HUB - IHR / WINTER ISSUE 2020-2021

we have produced first-class, industry-leading trade shows, connecting thousands of retailers to suppliers and manufacturers allowing them to have meaningful conversations and make lasting connections. We are building up from this foundation and have successfully pivoted our live trade shows to the virtual world, creating even more opportunities for collaboration and connection. This has also helped in our new direction and promise of delivering the benefits of our trade shows all year long with our new approach of “the show is always on.”

Quench-FX™

Alpha Science’s Quench-FX™ contains (per 1 capsule): Camellia sinensis (Green Tea Extract) (95% Polyphenols) .....................................................50 mg Citrus aurantium (Hesperidin) .......................................25 mg Counteracts oxidative stress Curcuma longa (Turmeric Extract) (95% Curcumin) .......15 mg An effective anti-inflammatory for organ systems as R-alpha-Lipoic acid .......................................................50 mg all antioxidants are anti-inflammatory Lycopersicon esculentum (Tomato Extract) Protects tissue and organs from free radicals (5% Lycopene)............................................................10 mg Supports cardiovascular pathways Pine Bark Extract (95% Proanthocyanidins) ..................50 mg Protects macula tissue Sophora japonica (Quercetin) ........................................50 mg Protects the testes, ovaries and prostate Tagetes erecta (Lutein)...................................................10 mg Supports immune and joint health Vaccinium myrtillus (Bilberry Extract)............................25 mg Provides antioxidants for optimal health Vitis vinifera (Grape Seed Extract) Protects the skin (95% Proanthocyanidins) .........................................100 mg Improves insulin sensitivity and glucose tolerance Vitis vinifera (Red Wine Extract) (50% Polyphenols) ......50 mg

NPN 80031616 Multi-Organ Protection

✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓ ✓

Quench-FX™ contains 11 different antioxidants sequestered in and thus protects the body’s main organ systems. It is effective against all free radicals (oxygen derived, nitrogen derived, single element e.g. Cl2).

AlphaScienceLabs.com • 1-888-299-0318 • 795 Pharamacy Ave., Toronto, ON M1L 3K2 CANADA

YOUR IMMUNE PROTECTION. OUR IMMUNE TEAM.

For your immune protection, there’s nothing like our immune team.

From stress relief and immunity optimizing formulations such as the award-winning PURICA Immune 7, PURICA Complete 360 and PURICA Vitality to our full line of organic,micronized medicinal mushrooms, we have you covered.

Shop online at purica.com or visit a store near you.

proudly made in canada since vegan

GF

gluten-free

1999

GMO non-gmo

Nature. Science. You.