SCOPE 2020

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When the mRNA enters the body’s lymph nodes, it instructs

their use will likely be much more prominent in the near future.

immune cells to produce the spike proteins on their outer cell

There are concerns that vaccinations against SARS-CoV-2

membranes, as if they had been infected by SARS-CoV-2 [9]

might not actually provide long term immunity [11]. Scientists

[10]. This enables B lymphocytes to produce complimentary

are unsure how the combination of antibodies, cells, and other

antibodies to the antigens on the spike proteins. Very similar

markers in a person’s blood will dictate their level of immunity. It

to the process mentioned previously, memory T and B cells

is known that some level of immunity is provided for an unknown

are then able to ‘remember’ how to produce these antibodies

length of time, but other factors such as viral mutations may

to fight against future infection from the virus. Moderna have

affect this drastically. There is also some debate concerning the

already begun production of this vaccine (subsidised by the US

danger that these vaccines have to the body, especially the mRNA

Government) despite the fact it has not been cleared for general

vaccines due to their novelty. Vaccine development for SARS-

use, which is a significant risk but means that if the vaccine is

CoV-2 has been the fastest ever, and this is a testament to the

successful, the infrastructure is already in place to mass-produce

significant advances in scientific research over the past decades.

the vaccine [12]. No mRNA vaccine has been approved before

The only chance that the world has in returning to some sense of

for an infectious disease as it is such a novel approach, however

normality is the widespread distribution of an effective vaccine.

The development of vaccines in the fight against SARS-CoV-2


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