The future of chromatography is with Axcend & Greenwood Products

The Axcend Focus LC in partnership with

The Future of HPLC is Here Today™

www.greenwoodprod.com John Stimus, Florida Account Manager 813-407-1450 jstimus@greenwoodprod.com Bob Scott, Account Manager 848-391-8197 bob@greenwoodprod.com

®

With over 50 years of high-performance liquid chromatography history as our guide, we deliver the future of HPLC to you today.

Small and Powerful The Axcend Focus LC® is a revolutionary, shoebox-sized HPLC. But don’t let its small size fool you. With a pressure range of up to 10,000 psi, nano-flow capillary columns, and single or dual UV-detectors for on-column detection, Axcend’s sleek and miniaturized system delivers results on par with today’s leading HPLC platforms.

Lightweight and Portable Why does the Axcend Focus LC have a handle? Because at under 18 pounds, this instrument is literally hand-portable and can be used anywhere, including any place within your laboratory, close to the ion source of a mass spectrometer, inside a fume hood, on a factory floor, and in the field. Small solvent and waste vials are even enclosed inside the Axcend Focus LC so you don’t have to worry about transporting separate solvent or waste bottles when you move the device.

At under 18 pounds, the Axcend Focus LC is literally hand-portable and can be used anywhere 2 1-888-299-9907 / info@greenwoodprod.com

Unique Cartridge System Key to the breakthrough design of the Axcend Focus LC is our creation of compact, easy-to-use cartridges that contain our UV-detectors and capillary columns supporting flow rates as low as 800 nL/minute. A cartridge (and consequently the column) slides easily into an Axcend Focus LC and is then hand-tightened into place by twisting the AssurLoc™ knob on the front of the instrument; this obviates the need for any wrenches or tools and saves significant time. In fact, changing a column is as simple as swapping cartridges, and a variety of detector and column configurations are available.

Delivers savings of 90% or more from reduced solvent needs and lower waste disposal costs

Dramatic Reduction in Solvent Use and Costs By using small-diameter capillary columns with on-column UV-Absorption detection at extremely low flow rates, you will see a dramatic reduction in solvent use of up to 90% or more with the Axcend Focus LC. This translates into huge savings in solvent costs as well.

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Dramatically Less Waste and Lower Disposal Costs Not only does the Axcend Focus LC use significantly less solvent to get the same results as traditional HPLCs, this instrument also generates comparably less waste — a lot less. In fact, you should see waste production and disposal cost reductions of 90% or more with the Axcend Focus LC.

The Axcend Focus LC uses so little solvent that our waste and solvent vials are contained within the instrument itself.

Lower Purchase Cost UV detection of five cannabinoids at 255 nm using the Axcend Focus LC. Elution Order — 3.3 min: CBDA; 3.6 min: CBD; 5 min: CBN; 5.8 min: Δ9-THC; and 7 min: THCA-A. Flow rate: 3 µL/min; Gradient: 65% - 85% B, 10 min; Equilibration Time: 2 min; Mobile Phase A (3:97:0.1 acetonitrile [ACN]:water [H2O]:trifluroacetic acid [TFA]); Mobile Phase B (97:3:0.1 ACN:H2O:TFA); Column: 10 cm x 150 µm i.d.; 1.8 µm C18.

In addition to the benefits noted above, the Axcend Focus LC features an extremely affordable price point vs. traditional HPLCs, delivering even more value to you.

A truly “green” HPLC that is “friendly” to the planet, you and your team

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A Truly Green HPLC Such a huge reduction in solvent usage and waste production means that the Axcend Focus LC is environmentally unmatched — a truly “green” HPLC that is “friendly” to the planet, you and your team.

A revolutionary, shoebox-sized HPLC on par with today’s leading HPLC platforms

The TCO Winner When taken together …

• Its lower purchase price as a truly “green” HPLC, with • Lower waste production and costs, and • Lower solvent use and costs, plus • A unique, easy-to-use cartridge system that • Houses nano-flow capillary columns, with • On-column, UV-Absorption detectors • Inside a powerful yet lightweight, shoebox-sized HPLC … it’s clear that the Axcend Focus LC delivers the winning combination that also lowers your overall Total Cost of Ownership (TCO) in the HPLC market.

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The Axcend Focus LC dramatically lowers solvent use and waste production making it a truly “green” HPLC.

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See For Yourself But don’t take our word for it. Find out for yourself how Axcend delivers the HPLC of the future today — a solution that makes HPLC Anywhere™ a reality.

Overlapping chromatograms of 55 runs acquired over 12 hours with the Axcend Focus LC. Flow rate: 2 µL/min; Gradient: 5% - 95% B, 0-5 min.; Equilibration Time 0.5 min; Mobile

Phase A (97:3 Water:AcN); Mobile Phase B (3:97 Water:AcN); Column: 10 cm x 150 µm i.d.; 1.7 µm C18 column; Injection volume: 40 nL; Detection: UV at 255 nm. Elution peak order: acetaminophen, caffeine, aspirin.

Sign-up today for a hands-on (or Web-based) demonstration of the Axcend Focus LC. Then you’ll understand why we say the “The Future of HPLC is Here Today.”

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Axcend Focus LC Specifications PHYSICAL SPECIFICATIONS Axcend Focus LC (Height x Width x Depth) 20.1x23.1x32.0 cm (7.9x9.1x12.6 in) Weight (without cartridge): 7. 2 kg (1 . lbs) Axcend Focus LC Cartridges (Height x Width x Depth) 4.1x11.2x18.8 cm (1.6x4.4x7.4 in) Single detector cartridge: 0.26 kg (9.0 oz) Dual detector cartridge: 0.29 kg (10.1 oz) Solvent & Waste Vials (Height x Diameter) Solvent-A Vial: 6.0x1.6 cm (2.38x0.63 in) Solvent-A Vial (volume): 9.0 mL

SYSTEM FEATURES Pressure Up to 10,000 psi (

bar)

UV-Absorption Detectors (single or dual) 255 or 275 nm wavelength Capillary Columns (single or dual) Length: 50, 100, 150, 200, or 250 mm Packing Material , with other packing

Solvent-B Vial: 4.5x1.5 cm (1.75x0.56 in) Solvent-B Vial (volume): 5.0 mL

Flow Rate Range

Waste Vial: 7.0x2.0 cm (2.75x0.81 in) Waste Vial (volume): 17.0 mL

Delay Volume

0.5 — 10 uL/min

1.0 uL pH Range

INSTRUMENT CONTROLS Axcend Focus LC Cartridge Hand-tightened AssurLoc™ ferrule alignment and leak prevention Sample Delivery Topside port with manual or automated injection Solvent & Waste Vial Access Axcend Focus LC front panel Power

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SOLVENT & SAMPLE MANAGEMENT Number of Solvents Injection Volume Range Internal loop: 4, 10, 20, 30, or 40 nL External loop: 175 nL and greater Injection Modes Manual and automated Gradient Formation Flow Ramping Primary Wetted Materials •F used Silica • PEEK • 316 Stainless Steel Solvent & Waste Storage inside the Axcend Focus LC

SOFTWARE Secure wireless and wired HPLC output and control of the Axcend Focus LC occurs through computers

Computer Operating Systems Supported •W indows v7 and higher •M ac High Sierra and later • Ubuntu 16.04 and later

POWER SPECIFICATIONS AC DC (Battery)

Li-ion batteries) Operating Time 10+ hours without recharging Expected Life

Axcend, the Axcend logo, Axcend Focus LC, The Future of HPLC is Here Today, AssurLoc, and HPLC Anywhere are trademarks of Axcend. All other trademarks are property of their respective owners. Copyright 2019 © Axcend 5252 N. Edgewood Dr. #185, Provo, UT 84604 USA | 801-405-9545 | www.axcendcorp.com Greenwood Products Inc. 262 Old New Brunswick Rd., Ste. G, Piscataway NJ 08854 I 888-299-9907 I www.greenwoodprod.com