2021 TDDW Abstract Book

Page 57

2021 TDDW

Symposium (VIII) INTERVENTIONAL ONCOLOGY IN DIGESTIVE MEDICINE

LEGACY: LOCAL RADIOEMBOLIZATION USING GLASS MICROSPHERES FOR THE ASSESSMENT OF TUMOUR CONTROL WITH Y-90 Vivian Bishay Department of Radiology, Icahn School of Medicine at Mount Sinai Hospital, New York, NY, USA The LEGACY Study is the first multicenter study to report a high median perfused volume absorbed dose of 410 Gy with TheraSphere, which resulted in an 88% best response (84% complete response), durable tumor control and high overall survival rate in patients with early and advanced HCC.

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At three years the overall survival rate for patients was 93% in patients with transplant or resection following TheraSphere and 84% for patients who had TheraSphere as a primary treatment, with 96.8% of patients responding to treatment following one TheraSphere treatment and 100% response with two treatments.


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