First Personalized Nanomedicine Symposium

D e pa rt m e n t o f I m m u n o l o g y Herbert Wertheim College of Medicine Fl o r i da In t e r nat i o na l Un i v e r s i t y

The Institute of NeuroImmune Pharmacology (INIP) & The Center for Personalized Nanomedicine (CPNM)

First Personalized

Nanomedicine Symposium Monday, February 18, 2013 MARC Pavilion, 7:30 a.m. – 6 p.m.

INIP CPNM – First Personalized Nanomedicine Symposium at FIU

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Mission The mission of INIP is to develop and sustain a program of translational research and training in drug use/abuse, tobacco use and HIV/AIDS. The Institute aims to promote interdisciplinary translational research focusing on the interactions of the human immune system, substance use/abuse, tobacco use, HIV infection, cancer and nanotechnology-based drug targeting.

CPNM is a research center at the Institute of NeuroImmune Pharmacology within the Department of Immunology at FIU’s Herbert Wertheim College of Medicine.

The CPNM focuses on current applications of nanotechnology in personalized medicine. This includes reconstructive surgery, targeted therapy, the latest research on nanodevices, drug development and delivery, the use of microelectronics and high precision lithography for the production of nanocomposites for personalized medical use. The Center involves researchers at FIU and across the globe. The CPNM’s main partners include the University of California, Emory University, Miami Children’s Hospital, Cleveland Clinic, and Baptist Hospital. The Center’s research has been funded by the National Institutes of Health (NIH), the National Science Foundation (NSF), the Department of Defense (DoD) and other state, federal and private foundations.

Need Photo of MARC Bldg.

INIP CPNM – First Personalized Nanomedicine Symposium at FIU

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NIH Panel Kendall Bryant, Ph.D. Director, Alcohol and AIDS Research National Institute on Alcohol Abuse and Alcoholism National Institutes of Health

Jeymohan Joseph, Ph.D. Chief, Neuropathogenesis and Treatment Program HIV Neuropathogenesis, Genetics, and Therapeutics Branch National Institutes of Health

Jag Khalsa, Ph.D. Chief, Medical Consequences Branch, Division of Pharmacotherapies and Medical Consequences National Institutes of Health

Belinda Seto, Ph.D. Deputy Director, National Institute of Biomedical Imaging and Bioengineering National Institutes of Health

Christopher Weis, Ph.D. DABT Toxicology Liaison / Senior Advisor, Office of the Director—National Institute of Environmental Health Sciences National Institutes of Health

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INIP CPNM – First Personalized Nanomedicine Symposium at FIU

The Institute of NeuroImmune Pharmacology (INIP) & The Center for Personalized Nanomedicine (CPNM)

First Personalized

Nanomedicine Symposium Conference Agenda Registration 7:30 a.m. - 8:00 a.m.

Welcome – Breakfast 8:00 a.m. - 8:30 a.m.

Ileana Varela

Associate Director of Marketing and PR FIU Herbert Wertheim College of Medicine

8:30 a.m. - 8:40 a.m.

Douglas Wartzok Ph.D.

Provost & Executive Vice President FIU

8:40 a.m. - 8:50 a.m.

John A. Rock, M.D., M.S.PH.

Founding Dean, FIU Herbert Wertheim College of Medicine Senior Vice President for Health Affairs FIU

Keynote Speaker 8:50 a.m. - 9:20 a.m. Molecular Medicine: Mechanism-Based Approaches

Belinda Seto, Ph.D.

Deputy Director National Institute of Biomedical Imaging and Bioengineering National Institutes of Health

Introduced by Madhavan Nair, Ph.D. Associate Dean, Biomedical Research Co-Director, Center for Personalized Nanomedicine FIU Herbert Wertheim College of Medicine

INIP CPNM – First Personalized Nanomedicine Symposium at FIU

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Session 1

Nanomaterials and Nanodevices Introduced by: Arvind Agarwal, Ph.D. Professor, Department of Mechanical and Materials Engineering, FIU College of Engineering and Computing

Chair: Christopher Weis, Ph.D. DABT Toxicology Liaison, Senior Advisor, Office of the Director National Institutes of Health

Co – Chair: Jeymohan Joseph, Ph.D. Chief, Neuropathogenesis and Treatment Program National Institute of Mental Health, National Institutes of Health 9:20 a.m. – 9:40 a.m. Biomimetic Nanomedicine: Protocells and Virus-like Particles against Cancer and Infectious Disease

Eric Jakobsson, Ph.D. Professor, The School of Molecular and Cellular Biology University of Illinois at Urbana – Champaign

9:40 a.m. – 9:55 a.m. Applications of Carbon Nanotubes in Biology and Medicine

Robert Haddon, Ph.D.

Distinguished Professor of Chemical and Environmental Engineering, University of California, Riverside

9:55 a.m. – 10:15 a.m. Multifunctional Nanoparticles to Enable Personalized Nanomedicine

Sakhrat Khizroev, Ph.D.

Professor and Vice Chair, Department of Immunology Director, Center for Personalized Nanomedicine, FIU Herbert Wertheim College of Medicine

10:15 a.m. – 10:35 a.m. Nanoscale Regenerative Rare Earth Oxides for Nanomedicine

Sudipta Seal, Ph.D.

Professor, Advanced Materials Processing and Analysis Center (AMPAC), University of Central Florida

10:35 a.m. – 10:50 a.m. BREAK 6

INIP CPNM – First Personalized Nanomedicine Symposium at FIU

Session 2

Nanoengineering and Single Molecule Imaging Introduced by: Amir Mirmiran, Ph.D., P.E. Professor of Civil Engineering, Dean, FIU College of Engineering and Computing

Chair: Belinda Seto, Ph.D. Deputy Director National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health

Co – Chair: Aftab Ahmed Ansari, Ph.D. Professor of Pathology, Emory University 10:50 a.m. – 11:10 a.m. Engineering Feedback System Control (FSC) Enabled Personalized Medicine

Chih-Ming Ho, Ph.D. Ben Rich-Lockheed Martin Chair Professor Henry Samueli School of Engineering and applied science Department of Mechanical & Aerospace Engineering Department of Bioengineering, UCLA

11:10 a.m. – 11:30 a.m. Nanobioelectronics for Theranostics

Chenzhong Li, Ph.D.

Associate Professor Department of Biomedical Engineering FIU

11:30 a.m. – 11:50 a.m. Enhanced Diagnostic Magnetic Resonance Imaging

Ping Liang, Ph.D.

Associate Professor Department of Electrical Engineering University of California, Riverside

11:50 a.m. – 12:10 p.m. Single-Molecule Enzymology with Nanometer-Scale Electronics

Gregory Weiss, Ph.D.

Professor, Department of Chemistry University of California, Irvine

12:10 p.m. – 1:15 p.m. LUNCH (FROST MUSEUM CAFE) INIP CPNM – First Personalized Nanomedicine Symposium at FIU

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Session 3

Nanoengineering for Personalized Medicine Introduced by: Carolyn Runowicz, M.D. Executive Associate Dean for Academic Affairs Professor of Obstetrics and Gynecology FIU Herbert Wertheim College of Medicine

Chair: Jag Khalsa, Ph.D. Chief, Medical Consequences Branch, Division of Pharmacotherapies and Medical Consequences of Drug Abuse, National Institute on Drug Abuse, National Institutes of Health

Co – Chair: Walter Royal, III, M.D. Director, The Maryland Center for Multiple Sclerosis Treatment and Research University of Maryland 1:15 p.m. – 1:35 p.m. Anti-Angiogenic Nanotherapy for the Treatment of Inflammatory Arthritis

Christine Pham, M.D. Associate Professor, Division of Rheumatology Washington University School of Medicine

1:35 p.m. – 1:55 p.m. Nanomotor and RNA Nanotechnology for Personated Nanomedicine

Peixuan Guo, Ph.D.

William Farish Endowed Chair in Nanobiotechnology Director, Nanobiotechnology Center, University of Kentucky

1:55 p.m. – 2:15 p.m. A Nanotechnology Approach to Protect Human Neurons and Glia from Oxidative Stress

Anuja Ghorpade, Ph.D.

Chair, Department of Cell Biology and Anatomy University of North Texas Health Science Center

2:15 p.m. – 2:35 p.m. Epigenetic Modulation for Cancer Therapy

Vinod Labhasetwar, Ph.D.

Professor, Department of Biomedical Engineering (ND20) Cleveland Clinic Lerner Research Institute

2:35 p.m. – 2:50 p.m. BREAK

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INIP CPNM – First Personalized Nanomedicine Symposium at FIU

Session 4

New Engineering for Personalized Diagnostics/ Treatments Introduced by: Andrés G. Gil, Ph.D. Vice President for Research Professor of Social Work FIU

Chair: Kendall Bryant, Ph.D. Director, Alcohol and AIDS Research, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health

Co – Chair: Michal Toborek, MD, Ph.D. Professor and Vice-Chair, Research Department of Biochemistry and Molecular Biology, University of Miami, Miller School of Medicine 2:50 p.m. – 3:10 p.m. Epitope Presentation Using Gold Nanoparticles for Immunoassay Development and In Vivo Studies

David Cliffel, Ph.D. Associate Professor, Department of Chemistry Vanderbilt University

3:10 p.m. – 3:30 p.m. Pre-Clinical Models of Personalized Medicine: Monitoring Therapy with Non-Invasive Imaging

Francois Villinger, D.V.M., Ph.D.

Professor, Division of Pathology Emory University School of Medicine

3:30 p.m. – 3:50 p.m. Targeting MicroRNAs to Ovarian Cancer

Sundaram Ramakrishnan, Ph.D.

Professor, Department of Pharmacology University of Minnesota

3:50 p.m. – 4:10 p.m. Immunomodulatory Nano-Scale Coatings for Islet Transplantation

Cherie Stabler, Ph.D.

Associate Professor, Biomedical Engineering Diabetes Research Institute, University of Miami

4:10 p.m. – 4:25 p.m. BREAK

INIP CPNM – First Personalized Nanomedicine Symposium at FIU

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Panel Discussion 4:25 p.m. – 5:25 p.m.

PANEL DISCUSSION

Leaders:

Robert Haddon, University of California, Riverside Jag Khalsa, NIH Christopher Weis, NIH/NIEHS Paul S. Weiss, University of California, Los Angeles

Discussants:

Kendall Bryant, NIAAA/NIH

Sulie Chang, Seton Hall University

David Cliffel, Vanderbilt University

Peixuan Guo, University of Kentucky

Chih-Ming Ho, UCLA

Eric Jakobsson, University of Illinois

Jeymohan Joseph, NIMH/NIH

Sakhrat Khizroev, FIU

Mahendra Kumar, University of Miami

Ping Liang, University of California, Riverside

Anthony McGoron, FIU

Sanjay B. Maggirwar, University of Rochester

Medical Center

Zubin Panthaki, University of Miami

Christine Pham, Washington University

Sabita Roy, University of Minnesota

Francois Villinger, Emory University

Gregory Weiss, University of California, Irvine 5:25 p.m. – 5:55 p.m. Summary - Panel Discussant Leaders 5:55 p.m. – 6:00 p.m. Thank You

Sakhrat Khizroev, Ph.D. Professor and Vice Chair, Department of Immunology Director, Center for Personalized Nanomedicine, FIU Herbert Wertheim College of Medicine

6:00 p.m. – 7:00 p.m. DINNER (FROST MUSEUM CAFE)

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INIP CPNM – First Personalized Nanomedicine Symposium at FIU

Thank You We would like to express our sincere appreciation to all attendees of today’s First Personalized Nanomedicine Symposium 2013. This event will open the doors to individualized treatment paradigms for the diagnosis and treatment of patients. Your participation has been invaluable to this event and will help it to become the premier vehicle for knowledge and innovation to professionals in this field. You are making a difference and we are honored to have you as our guests. Thank you for your support.

Madhavan Nair, Ph.D. Professor and Founding Chair, Department of Immunology Director, Institute of Neuroimmune Pharmacology Associate Dean, Biomedical Research FIU Herbert Wertheim College of Medicine

Sakhrat Khizroev, Ph.D. Professor and Vice Chair, Department of Immunology Director, Center for Personalized Nanomedicine FIU Herbert Wertheim College of Medicine

INIP CPNM – First Personalized Nanomedicine Symposium at FIU

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Florida International University Herbert Wertheim College of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Florida International University Herbert Wertheim College of Medicine designates this live activity for a maximum of 6.5 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

The FIU Herbert Wertheim College of Medicine is fully accredited by the Liaison Committee on Medical Education (LCME).

go.fiu.edu/nanomedicine

Herbert Wertheim College of Medicine 11200 SW 8th Street, AHC2 Miami, FL 33199 305-348-0570 | medicine.fiu.edu