FIU MED Annual Report 2016-17

F L O R I D A I N T E R N AT I O N A L U N I V E R S I T Y

HERBERT WERTHEIM COLLEGE OF MEDICINE

2015-2016 Annual Report

CONTENTS

“

THE COLLEGE OF MEDICINE AND THE COMMUNITY SHOULD BE SEAMLESS.

QUOTE

“

YOU SHOULD NOT BE ABLE TO TELL WHERE ONE ENDS AND THE OTHER BEGINS. – Dr. Herbert Wertheim

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dean’s message

CONTENTS Education + Training Excellence........... 4 Health Care Innovation + Community Health..................................12 Research + Evaluation.............................20 Faculty + Staff Success...........................24 Strategic Partnerships..............................28 Diversity..........................................................30 Philanthropy..................................................34 Facts + Figures............................................36 Selected Published Articles...................39

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TEN YEARS AGO, THE FLORIDA LEGISLATURE AUTHORIZED CREATION OF A MEDICAL SCHOOL AT FIU, AND WE PROMISED TO CHANGE THE FUTURE OF MEDICAL EDUCATION AND HEALTH CARE IN OUR COMMUNITY. A DECADE LATER, WE ARE PROUD TO REPORT THAT WE HAVE KEPT OUR PROMISE.

W

e are training students to become physicians who understand the social determinants of health, and to understand that a patient’s zip code is a better predictor of his or her health than a genetic code. Medical student Lisa Podolsky recognized that a patient with hypertension and diabetes whom she encountered during a family medicine rotation didn’t need a lecture about maintaining a proper diet or prescriptions for medications she couldn’t afford; that patient needed a comprehensive plan of medical and social support. Another student, Sean Hernandez, encountered a hospice patient who spent all of her time silently knitting; Sean learned to crochet as a way of engaging the woman. Lisa and Sean graduated in May and are now in residency programs in obstetrics and gynecology at Rutgers University and internal medicine at Wake Forest School of Medicine.

These students are part of the legacy of Herbert Wertheim College of Medicine (HWCOM) and its unique and innovative Green Family Foundation Neighborhood Health Education and Learning Program (NeighborhoodHELP™).

NeighborhoodHELP™ immerses faculty-supervised interprofessional teams of FIU medical, nursing, social work, and physician assistant students (and education and law students as household needs are identified) into the local community to provide care and facilitate services to households in medically underserved neighborhoods in Miami-Dade County. Since the launch of NeighborhoodHELP™, FIU students have conducted more than 6,000 household visits to more than 700 households, impacting approximately 2,000 household members. NeighborhoodHELP™ also provides patients with primary and mental health care through four mobile health centers. One of those—the Linda Fenner 3D Mobile Mammography Center—provides mammography services to women in South Florida neighborhoods known to have the highest rates of late-state breast cancer detection in the nation. To date, we have conducted free screenings for more than 1,400 women.

We are improving health care and saving lives, and for every dollar invested in NeighborhoodHELP™, we are supporting a return of more than $13 in economic and societal benefits.

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These accomplishments have not gone unnoticed.

In 2015, HWCOM became one of only 32 schools chosen by the American Medical Association to participate in the Accelerating Change in Medical Education Consortium, and in 2016, the college was awarded the Association for Medical Education in Europe’s ASPIRE-to-Excellence Award in Social Accountability. These accomplishments have been possible with the support of our community and community partners—the households that open their doors to our students, the patients who put their health in our hands, and the 160 community organizations that help bring us together. We are indebted to each and every one of these partners and community members.

We are also grateful for the tremendous support of our affiliated institutions and faculty. FIU does not own or operate its own hospital; rather, students receive training in many of South Florida’s finest health systems, hospitals, and clinics. More than 2,000 faculty members—many of whom are volunteer, community-based physicians—dedicate their time and expertise to facilitate the training of medical students.

In 2009, the college welcomed its first cohort of medical students. These students have since graduated, and the doctor of medicine degree program has reached full capacity of approximately 480 students. Some of our alumni, like Dr. Hanadys Ale, are treating patients right here in South Florida.

Many of our graduates are choosing careers in primary care, a field in which there is a current need for physicians.

We are proud of our current students, our alumni, our faculty, and our staff, and we are grateful for the community’s unwavering support.

Thank you, South Florida.

John A. Rock, MD Founding Dean and Senior VP for Health Affairs FIU Herbert Wertheim College of Medicine

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EDUCATION + TRAINING EXCELLENCE

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We have developed a doctor of medicine degree program that reflects an innovative, twenty-first-century approach to health care and medical education. We are training students to become great physicians and community leaders who think holistically, globally, and locally.

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education

+ training excellence

UNDERGRADUATE

USMLE test scores HWCOM medical students have consistently performed at a high level, scoring higher than the national averages on the USMLE Step 1 for the past five years.

98% PASS RATE

Pass rate 95% for the 2016 Step 2 Clinical Knowledge

AMA Accelerating Change in Medical Education

The American Medical Association’s Accelerating Change in Medical Education Consortium is studying ways to reshape the training of future physicians in order to improve health outcomes.

In November 2015, HWCOM was selected to join the consortium.

Med students chosen for NIH Medical Research Scholars Program Nicole Colwell and Jason Alvarez were two of only 55 students nationwide chosen to spend a year working with some of the best clinicians and scientists in the world.

They are pursuing cuttingedge biomedical research at the National Institutes of Health Clinical Center in Bethesda, Maryland, after being selected in 2015 to the prestigious Medical Research Scholars Program.

107 OF 108 STUDENTS IN THE CLASS OF 2016 MATCHED TO RESIDENCY POSITIONS. 6

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EPA Pilot

In May 2014, the Association of American Medical Colleges published the Core ENTRUSTABLE PROFESSIONAL ACTIVITIES for Entering Residency, a set of 13 tasks and responsibilities that a beginning resident should be able to perform without direct supervision.

HWCOM is one of 10 medical schools, from more than 70 that applied, chosen to participate in a 5-year pilot program to determine the feasibility of implementation of the EPAs into undergraduate medical education.

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GRADUATE AND POST-GRADUATE

Graduate Medical Education Working with our affiliated hospitals, we have helped create or support more than

200 resident positions in South Florida.

Master in Physician Assistant Studies (MPAS)

To help meet the growing demand for health care practitioners, HWCOM launched a 27-month Master in Physician Assistant Studies degree program in fall 2015.

HWCOM received approximately 700 applications for the 45 inaugural slots.

Graduate Certificate in Molecular and Biomedical Sciences

The Graduate Certificate in Molecular and Biomedical Sciences program is designed to strengthen the biomedical and knowledge professionalism skills of students. The program is designed to improve participants’ qualifications for future application to medical school or other health-related professional degree programs. The certificate program welcomed its inaugural class of 48 students in August 2016.

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MATCH DAY

is the annual, nationwide rite in which graduating students learn where they’ll be training in their chosen specialties.

Watch a video at go.fiu.edu/Matchday2016

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99% MATCH RATE

15.2% Sixteen students matched into residency positions in Florida.

10.5% Eleven of these are continuing their medical training right here in South Florida.

58.1% Sixty-one students matched to

primary care residency* positions, during a time in which there is a need for primary care physicians. *Bureau of Health Professions

Vincent Boston, Class of 2016, after learning he had matched to the emergency medicine residency program at Barnes-Jewish Hospital in St. Louis, MO.

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education

+ training excellence

ALUMNI

Dr. Hanadys “Hany” Ale Only seven years ago, Hanadys Ale, who had interrupted her medical studies in her native Cuba to move to Miami with her family, roamed the corridors at Nicklaus Children’s Hospital (then Miami Children’s) pushing a shopping cart full of games and toys. A “Bedside Buddy” volunteer, she engaged patients, asking if they wanted to play games like UNO, Candyland, and Operation.

She also watched the doctors and residents at work, wishing she could be one of them. Today she is one of them. “It’s like a dream come true for me,” says Dr. Ale, the first fellow in the Miami Children’s Health System’s new Allergy and Immunology Fellowship Program (in collaboration with the Cleveland Clinic of Florida). Dr. Ale, one of 33 graduates of the HWCOM inaugural class, also completed her residency in pediatrics at Nicklaus Children’s Hospital; she was committed to staying in South Florida to serve the community that had welcomed her family and given them a second home.

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THE MEDICAL ALUMNI NETWORK,

launched in July 2015, offers networking and volunteering opportunities for HWCOM alumni.

HWCOM already boasts

263 alumni completing residencies

in 28 states. vermont

2

massachusetts

1

6

new york

minnesota

36

michigan

3

pennsylvania

13

illinois

7

5

indiana

1

west virginia

1

2

california

23

kentucky tennessee

1

6

ohio

colorado

conneticut new jersey

delaware

1

4

5

north carolina

12 maryland

arizona

virginia

3

8

7

georgia

south carolina

6

texas

13

6

louisiana

13

florida

66

For an interactive map please visit go.fiu.edu/alumnimap2016

Dr. Daniel “Danny” Castellanos Another graduate of the inaugural Class of 2013, Dr. Castellanos is a first-year pediatric cardiology fellow at Texas Children’s Hospital. He completed his residency in pediatrics at Children’s Hospital Los Angeles. During his tenure there, he was twice nominated by the interns to receive the Roberta G. Williams Outstanding Teaching Award given to outstanding senior residents. Dr. Castellanos was also awarded Best Poster in Clinical Research, Saban Research Institute of Children’s Hospital Los Angeles, 20th Annual Poster Session (2015), and published a paper, Castellanos DA, Herrington C, Adler S, Haas K, Kumar SR, Kung G, Home Monitoring Program Reduces Mortality in High-Risk Sociodemographic Single-Ventricle Patients.

Pediatric Cardiology. 2016 ;37(8):1575-1580. doi: 10.1007/s00246-016-1472-x

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HEALTH CARE INNOVATION + COMMUNITY HEALTH

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Our commitment to community is real.

Our approach integrates medical education, household visits, community engagement, and health care services through household-centered care.

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health care innovation

+ community health

Green Family Foundation

NeighborhoodHELP™ The Green Family Foundation Neighborhood Health Education Learning Program

(NeighborhoodHELP™) is the platform through which HWCOM engages with the community and emphasizes social accountability and interprofessional household-centered care. Through this novel, service-learning program, medical students are immersed in the community as members of interprofessional teams that include nursing, social work, and physician assistant students (and education and law students as household needs are identified). During household visits —which continue over three years— students take comprehensive patient and household histories, and develop care plans to improve the health and quality of life of household members.

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Linda Fenner 3D Mobile Mammography Center Made possible by generous donations from the Braman Family Charitable Foundation and the Batchelor Foundation, the Linda Fenner 3D Mobile Mammography Center offers free breast health screenings, health education, and navigation services for women without access to care in Miami-Dade County. The Center provides services in collaboration with various organizations, including the Florida Department of Health, federally qualified health centers, cancer support and advocacy groups, places of worship, and shelters for people experiencing homelessness.

Watch a video at go.fiu.edu/LFMMCfyh

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HouseholdCentered Care P

rs Facult

Community Assets

y an d S taf f

State & Federal Government

Civic Infrastructure

Com

Local Businesses

rofessional er-p eams t n I nt T U FI tude S

mu nit y

e tn

Mo bi l

He

Com

ar

e

rs ente C h alt

Addressing the critical need for enhanced primary and preventive care services in NeighborhoodHELP™ communities, the program has integrated health care services for household members. To overcome access barriers and to connect people to the health system, health care services are provided through mobile health centers at community sites; as needed, patients are referred to other community providers.

munity Health C are Providers

NeighborhoodHELP™ has incorporated four mobile health centers that provide a broad range of integrated primary, preventive, and behavioral health services, and chronic disease management for household members.

4

mobile health centers

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ASPIRE Award

The Association for Medical Education in Europe (AMEE) recognized HWCOM’s unique approach to medical education by selecting the college as a recipient of the 2016 ASPIRE-toExcellence Award in Social Accountability.

AMEE is the leading international medical association for medical schools, and has 90 members on five continents.

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chapter

:

subchapter

416 medical, nursing, social work, and law students conducted 1,

From July 1, 2015, through June 30, 2016, a total of

614 PATIENTS WERE SEEN +

2,907

VISITS MADE AT

MOBILE HEALTH CENTERS.

DENTAL HEALTH INITIATIVE: 745 DENTAL SCREENINGS HAVE BEEN CONDUCTED + 200 REFERRALS HAVE BEEN MADE to community dental providers.

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ted

=

1,990 visits to 526 households with 1,462 members.

LINDA FENNER 3D MOBILE MAMMOGRAPHY CENTER: From July 1, 2015, through June 2016,

912

MAMMOGRAPHY SCREENINGS CONFIRMED CASES OF EARLY-STAGE BREAST CANCER.

8

1 NEIGHBORHOODHELPâ„¢ $ 13.15 $

For every

invested in

is generated within the Florida economy.

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health care innovation

+ community

FIU Health Ambulatory Care and Surgery Center Opening In May 2015, HWCOM, in partnership with Miami-Dade County, opened the FIU Health Ambulatory Care and Surgery Center on FIU’s Modesto A. Maidique Campus. The twostory facility houses HWCOM’s clinical faculty group practice and the Miami Children’s Hospital Ambulatory Surgical Center, the first dedicated pediatric ambulatory surgical center in South Florida.

At our on-campus facility, FIU Health provides services in dermatology, family medicine, internal medicine, gynecology, weight management metabolic and bariatric surgery, psychiatry and behavioral health, and travel medicine. At a second facilty located at the Broward Health Medical Center, we offer weight management metabolic and bariatric surgery, and psychiatry and behavioral health services.

FIU-FAST Watch a video at go.fiu.edu/FIU-FASTfyh

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The 36,000-square-foot facility houses FIU Health, HWCOM’s clinical faculty group practice, and the Miami Children’s Hospital Ambulatory Surgical Center

When disasters strike, time, training, and experience can mean the difference between life and death. The allvolunteer FIU-Florida Advanced Surgical Transport team (FIU-FAST) officially joined HWCOM in April 2016 through a partnership with the FIU Department of Emergency Management. The only civilian team of its kind in the nation, FIU-FAST is trained, ready, and equipped to treat and evacuate critical care patients following a terrorist attack, natural disaster, or other major incident. This team of health care professionals has the ability and training to set up a ten-bed intensive care unit to perform life-saving surgical procedures and critical care, as well as transport critical care patients to and from hospitals in civilian or military planes.

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RESEARCH + EVALUATION

We received $5.8 million in research awards in 2015-16, an increase of 15% from the previous year.

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research

+ evaluation

J

EFF BOYD, PhD, is Professor and Chair of the Department of Human and Molecular Genetics, and Associate Dean for Basic Research and Graduate Programs. He and his team are working on the molecular genetics of gynecologic and breast cancers. “We believe that the key to truly effective cancer therapy is to develop novel targeted agents that selectively kill cancer stem cells, which are responsible for cancer recurrence and metastasis, the events responsible for cancer mortality” says Boyd. Working with DIANA AZZAM, PhD, he is using a highthroughput screening approach (developed

by Azzam) to identify new molecules with a high therapeutic index against breast and ovarian cancer stem cells. Then they can develop a targeted approach to killing the specific tumor, the essence of “translational research.” Boyd is also Director of Translational Research and Genomic Medicine at the new Miami Cancer Institute at Baptist Health South Florida.

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Our partnership with Baptist Health South Florida has facilitated recruitment of faculty members to expand our translational research and the cancer and genomics research portfolio: Jeff Boyd, PhD; Miguel Villalon-Calero, MD; Diana Azzam, PhD; and Wenrui Duan, PhD.

Watch a video at go.fiu.edu/Boydfyh

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Watch a video at go.fiu.edu/Ovarianfyh

Ovarian cancer is the fifth leading cause of cancer-related death among women in the US. HWCOM researchers Carolyn Runowicz, MD, and Sakhrat Khizroev, PhD, have developed what could be a breakthrough in the treatment of ovarian cancer: a novel way to deliver drugs that attack and kill cancer cells while leaving normal cells intact. Their studies involve loading the chemotherapy drug taxol onto a magnetoelectric nanoparticle (MENS), and using an electric field to penetrate and destroy tumor cells.

Florida Medical Student Research Journal (FMSRJ): Two HWCOM students—Editors in Chief Emily S. Andersen and Roy Lipworth—launched the Florida Medical Student Research Journal, one of just a few student research journals in existence across the country. FMSRJ allows students the unique opportunity to prepare for a future in academic medicine, and aims to bridge the gap during those early years of medical students’ careers when lack of familiarity with publishing and peer-review are most prevalent.

Fostering collaboration in science and research HWCOM hosted the Society for Personalized Nanomedicine’s 3rd Symposium bringing together at FIU the top basic science, translational, and clinical researchers from around the nation. These researchers shared the latest studies, important developments, and best research methods in the growing fields of nanomedicine and nanotechnology.

The Society is headed by HWCOM Distinguished Professor and Associate Dean for Bio-medical Research, Madhavan Nair, PhD.

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FACULTY + STAFF SUCCESS

Our WorldsAhead faculty and staff are the foundation of our students’ success. They continue to be recognized as some of FIU’s finest.

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faculty

+ staff success

Aileen M. Marty, MD Professor, Department of Humanities, Health, and Society Dr. Marty is one of 15 nationally recognized experts appointed to the US Presidential Advisory Council on Combating Antibiotic-Resistant Bacteria.

She also received FIU’s top faculty honor in 2015, the President’s Council WorldsAhead Faculty Award.

Luther Brewster, PhD Assistant Professor, Department of Humanities, Health, and Society Dr. Brewster was thirdplace recipient of the FIU 2015 WorldsAhead Faculty Award, and the winner of the Faculty Award for Excellence in Engagement.

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iLearn Lab and Faculty Resource Center The newly established Faculty Resource Center is designed to support faculty in their efforts to maximize student learning through development and use of multimedia and online platforms. In collaboration with the Office of Learning and Teaching, instructional designers assist faculty with the creation of innovative educational modules and tools for online delivery. Two new recording studios facilitate high-quality production. Instructional designers who have expertise in higher education instruction and pedagogy assist faculty with a variety of services, including designing lectures to maximize learning retention.

Using research-based instructional design principles, the instructional design team collaborates with faculty on the design of the online learning environment in CanvasMed (the HWCOM learning management system for students, faculty, and staff ) and on the design and development of online, multimedia lessons. The iLearn Lab, a state-ofthe-art physical space, is a multiuse and flexible training space where instructional designers and others engaged in faculty development conduct training sessions.

Ileana Varela, Associate Director for Marketing and Public Relations, led the HWCOM team that, in collaboration with FIU Media Relations, won the top award for Best Practices in Communications and Marketing and a special merit award for Media Relations Program from the Council for Advancement and Support of Education (CASE) District III, as well as the Public Relations Society of America Sunshine District 2015 Radiance Award in Media Relations. The awards stem from efforts surrounding Dr. Aileen Marty’s work fighting Ebola in West Africa, which additionally yielded an estimated $3.5 million in earned national and international media coverage.

Gagani Athauda, MD Assistant Professor, Department of Cellular Biology and Pharmacology Dr. Athauda won an FIU Faculty Award for Excellence in Teaching.

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Maria T. Martinez, right, patient navigator for the Linda Fenner 3D Mobile Mammography Center (with breast cancer survivor Daisy Angulo), received Breast Patient Navigator Certification from the National Coalition of Breast Cancer Centers.

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faculty

+ staff success

Strategic Partnerships

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Good Samaritan Medical Center (West Palm Beach)

POMPANO

Cleveland Clinic Florida

Memorial Hospital Miramar

Broward Health Imperial Point

Broward Health Medical Center

FORTLAUDERDALE

Memorial Regional Hospital

HOLLYWOOD

Joe DiMaggio Childrlen’s Hospital Aventura Hospital and Medical Center

Palmetto General Hospital

Jackson North Medical Center

MIAMI

Miami Jewish Health System Mount Sinai Medical Center

Citrus Health Network

Miami Veteran Affairs Healthcare System Jackson Memorial Hospital

Kendall Regional Medical Center

West Kendall Baptist Hospital

Baptist Hospital of Miami

Mercy Hospital Doctors Hospital South Miami Hospital

Nicklaus Children’s Hospital (Miami Children’s Health System)

Jackson South Community Hospital

HOMESTEAD

Homestead Hospital

South Florida Evaluation and Treatment Center

International Program The Office of International Affairs (OIA) at HWCOM was established in October 2013. Just four months later, OIA established the International Visiting Medical Student (IVMS) Program and hosted its first international student from Peru. IVMS was designed so that international students in their final years of medical school can gain a better understanding of best medical practices in the US, and can thus implement such practices when they return to their home countries. While enrolled in the program, students complete clinical electives with HWCOM faculty at one or more of 23 affiliated clinical sites dedicated for international students. Since its inception, OIA has hosted over 200 students from more than 20 countries in South America, Central America, Asia, Europe, Africa, and the Middle East.

Sites at which MD students rotate for required inpatient experiences

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Diversity

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Diversity is integral to our entire academic enterprise. We believe that blending different life and cultural experiences is important when selecting faculty, staff, and medical students and in educating future physicians.

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diversity

Top School for Hispanic Students:

The Association of American Medical Colleges

RANKED HWCOM FIRST IN THE NATION in 2015 in percentage of HISPANIC STUDENTS GRADUATED, 23.75%.

We were also first in Florida, and fifth in the nation in the total number of Hispanic graduates.

FSTAR Fellowship: The Florida Science Training and Research Fellowship (FSTAR) was established by the HWCOM Office of Diversity and Inclusion to increase the number of highly qualified medical school applicants from minority groups underrepresented in medicine. The program is funded through the Office of Minority Health. Each year, 15 sophomores are selected from partnering institutions to participate in FSTAR, and are provided with pre-med counseling and academic advisement, MCAT preparation, research and community-based experiences, and shadowing and leadership opportunities.

MORE Program: Our newest initiative, the Mentorship Opportunities Readiness Excellence (MORE) Program, is designed to increase the diversity of the health care workforce by exposing interested Native American students to various health care professions early in their education. This is achieved first through a rigorous five-week academic enrichment experience and subsequent follow-up and engagement over their school years. Native American students are prepared to be competitive future applicants to medical school and other health-related degree programs. The program is funded by the Seminole Tribe of Florida.

FSTAR received a $2.1 million grant in 2015, and is currently in its second year of funding, as one cohort has completed its first year in the program.

Lorena Perez Class of 2020 32

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High school students interested in careers in medicine attend the National Youth Leadership Forum at HWCOM.

Doctors of Tomorrow

The goal of the Doctors of Tomorrow Program is to increase the number of disadvantaged and underrepresented applicants gaining entrance to medical school. Thirty pre-med students are chosen each year for this intensive week-long residential program for highly motivated college students who are Florida residents. The program includes academic enrichment, learning skills development, communication skills development, counseling, career development, and character-building and enrichment activities.

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philanthropy

THANK YOU Dr. Albert and Debbie Tano, who served as co-chairs of this year’s Sapphire Gala and for whom the stateof-the-art Albert and Debbie Tano Simulation Center is named, continue to give our students the opportunity to learn the skills they need to improve the health of patients in our community. Dr. Tano has worked, taught, and volunteered in the field of neonatology since 1989, and Debbie Tano started working at the age of 14 to pay for college and attend nursing school. It is this hard work that allows them to understand the determination and drive of FIU medical students. Their invaluable generosity to HWCOM is assisting in the training of future physicians who will continue to serve and give back to the South Florida community, just as the Tanos have served and given back.

Funds from the Braman Family Charitable Foundation and the Batchelor Foundation continue to support the operations and activities of the Linda Fenner 3D Mobile Mammography Center, which seeks to “Drive Out Breast Cancer from Our Community.” More than 1,400 women have received free breast screenings since the Center was launched in 2014.

The VITAS Healthcare $25,000 Scholarship is designed to reduce the burden of medical education debt for a student at HWCOM. The student must successfully match into a primary care residency program and demonstrate a deep appreciation for the needs of terminally ill patients and their families. Class of 2015 grad Rachel Helm is the first VITAS Healthcare Scholarship recipient. She is pursuing a residency in pediatrics at Montefiore Medical Center in the Bronx, NY. Her long-term goal is to pursue a fellowship in pediatric palliative care.

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Sapphire Gala

In celebration of its tenth anniversary, HWCOM held the Sapphire Gala on Saturday, April 9, at the InterContinental Miami. The event brought together more than 500 of South Florida’s philanthropic, academic, medical, and business leaders for a black-tie event featuring a luxury silent auction, dinner, music, dancing, award presentations, and a raffle for a 2016 Red Corvette Stingray donated by Felix Sabates Chevrolet Cadillac. We raised more than $1 million for medical student scholarships and other programs.

Dr. A. Frederick and Judy Schild made a $25,000 gift to the HWCOM to dedicate an OSCE (objective structure clinical examination) room in honor of their grandsons, Samuel and Daniel Henschel. Through their generous support of clinical simulation education, the Schilds are impacting the educational experience of students for years to come, and are improving patient care and safety in our community as future doctors learn the skills they need to become outstanding physicians.

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facts

+ figures

2016 FACTS + FIGURES

Faculty

2,179

Student Population

Staff

468 PA....................................................................... 45 PhD..................................................................... 14

416

MD...............................................................

3,816 Accepted MD Students................... 126 MD Applicants..............................

Degrees Awarded

108

USMLE

2016 Average Scores Step 1 National

Step 2

Clinical Knowledge

National

229 242 .. ..

240 246 HWCOM

HWCOM

Alumni

263

*

*A few scores are still pending.

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Research Awards

5.8 Million

$

Residencies in Florida

$

Hospital and Health Center

Gifts and Spendable Interest

Partners

10.4 Million

$

17

25+

Endowment Value

55 Million

Miami is our home

$

Diversity of MD Student Body in 2016 35% Hispanic/Latino 9% Black/African American 47% Female 16% Economically disadvantaged 18% Out-of-State

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facts

+ figures

2016 FACTS + FIGURES Research Expenditures (5%)

Operating Budget General Revenue............................................. $ 41.0 M

Endowment Interest and Gifts (4%)

Auxiliaries (4%)

Clinical Revenue (3%)

Tuition..................................................................... $ 18.4 M Clinical Revenue.............................................. $ 2.0 M

Operating Budget

Research Expenditures............................... $ 3.8 M Endowment Interest and Gifts............... $ 2.9 M Auxiliaries............................................................. $

2.7 M

Total........................................................................ $ 70.8 M Tuition (26%)

General Revenue (58%)

5-Year Strategic Plan Update 2015 - 2016 Year One Accomplishments

Goal 1: Education + Training Excellence Goal 2: Health Care Innovation + Community Health

78% 50% 83%

Goal 3: Research + Evaluation Goal 4: Faculty + Staff Success Goal 5: Strategic Partnership

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SELECTED PUBLISHED ARTICLES Alexander Agoulnik, PhD, Professor, Human and Molecular Genetics Ferguson L, Kaftanovskaya EM, Manresa C, Barbara AM, Poppiti RJ, Tan Y, Agoulnik AI. Constitutive Notch signaling causes abnormal development of the oviducts, abnormal angiogenesis, and cyst formation in mouse female reproductive tract. Biol Reprod.

2016;94:67. doi: 10.1095/biolreprod.115.134569. PMID: 26843448.

Jeff Boyd, PhD, Chair and Professor, Human and Molecular Genetics Yan X, Hu Z, Feng Y, Hu X, Yuan J, Zhao SD, Zhang Y, Yang L, Shan W, He Q, Fan L, Kandalaft LE, Tanyi JL, Li C, Yuan CX, Zhang D, Yuan H, Hua K, Lu Y, Katsaros D, Huang Q, Montone K, Fan Y, Coukos G, Boyd J, Sood AK, Rebbeck T, Mills GB, Dang CV, Zhang L. Comprehensive genomic characterization of long non-coding RNAs across human cancers. Cancer Cell. 2015;28:529-540. doi: 10.1016/j.ccell.2015.09.006. PMID:26461095.

The Cancer Genome Atlas Network. The molecular taxonomy of primary prostate cancer. Cell. 2015;163:1011-1025.

The Cancer Genome Atlas Network. Comprehensive molecular characterization of papillary renal-cell carcinoma. N Engl J Med. 2016;374:135-145.

Luther Brewster, PhD, Associate Professor, Humanities, Health, and Society Brewster L. Academic health centers and diversity ‘‘readiness’’. South Med J. 2015;108:607-609.

David Brown, MD, Associate Professor, Humanities, Health, and Society Brown D, Gillespie C, Warren J. EPA 9—Collaborate as a member of an interprofessional team: a short communication from the AAMC Core EPAs for Entering Residency Pilot Schools. Med Sci Educ. 2016;26:457. doi 10.1007/s40670016-0273-4 Jeremy Chambers, PhD, Assistant Professor, Cellular Biology and Pharmacology Chambers TP, Portalatin GM, Paudel I, Robbins CJ, Chambers JW. Sub-chronic administration of LY294002 sensitizes cervical cancer cells to chemotherapy by enhancing mitochondrial JNK signaling. Biochem Biophys Res Commun. 2015;463:538-544. doi: 10.1016/j. bbrc.2015.05.075. PMID:26032505.

Paulo Chaves, MD, PhD, Associate Professor, Humanities, Health, and Society Vieira ER, Palmer RC, Chaves PH. Prevention of falls in older people living in the community. BMJ. 2016;353:i1419.

Kim DH, Grodstein F, Newman AB, Chaves PHM, Odden MC, Klein R, Sarnak MJ, Lipsitz LA. Microvascular and Macrovascular Abnormalities and cognitive and physical function in older adults: cardiovascular health study. J Am Geriatr Soc. 2015;63:1886-1893.

PMID:26338279.

Suzuki H, Kawai H, Hirano H, Yoshida H, Ihara K, Kim H, Chaves PHM, Minami U, Yasunaga M, Obuchi S, Fujiwara Y. One-year change in the Japanese version of the Montreal Cognitive Assessment performance and related predictors in community-dwelling older adults. J Am Geriatr Soc. 2015;63:1874-1879. PMID:26313522.

Ix JH, Biggs ML, Mukamal K, Djousse L, Siscovick D, Tracy R, Katz R, Delaney JA, Chaves PHM, Rifkin DE, HughesAustin JM, Garimella PS, Sarnak MJ, Shlipak MG, Kizer JR. Urine collagen fragments and CKD progression– the cardiovascular health study. J Am Soc Nephrol. 201526:2494-2503. PMID:25655067.

Garimella PS, Biggs ML, Katz R, Ix JH, Bennett MR, Devarajan P, Kestenbaum BR, Siscovick DS, Jensen MK, Shlipak MG, Chaves PHM, Sarnak MJ. Urinary uromodulin, kidney function, and cardiovascular disease in elderly adults. Kidney Int. 2015;88:1126-1134.

PMID:26154925.

Waheed S, Chaves PHM, Gardin JM, Cao JJ. Cardiovascular and mortality outcomes in the elderly with impaired cardiac and pulmonary function: the cardiovascular health study (CHS). J Am Heart Assoc. 2015;4. PMID: 26645833.

Kuźma E, Soni M, Littlejohns TJ, Ranson JM, van Schoor NM, Deeg DJ, Comijs H, Chaves PHM, Kestenbaum BR, Kuller LH, Lopez OL, Becker JT, Langa KM, Henley WE, Lang IA, Ukoumunne OC, Llewellyn DJ. Vitamin D and memory decline: two population-based prospective studies. J Alzheimers Dis. 2016;50:1099-1108. PMID: 26836174.Littlejohns TJ, Kos K, Henley WE, Lang IA, Annweiler C, Beauchet O, Chaves PHM, Kestenbaum BR, Kuller LH, Langa KM, Lopez OL, Llewellyn DJ. Vitamin D and risk of neuroimaging abnormalities. PLoS One. 2016;11.

Kuźma E, Soni M, Littlejohns TJ, Ranson JM, van Schoor NM, Deeg DJ, Comijs H, Chaves PHM, Kestenbaum BR, Kuller LH, Lopez OL, Becker JT, Langa KM, Henley WE, Lang IA, Ukoumunne OC, Llewellyn DJ. Vitamin D and Memory Decline: Two population-based prospective studies. J Alzheimers Dis. 2016;50:1099-1108.

Littlejohns TJ, Kos K, Henley WE, Lang IA, Annweiler C, Beauchet O, Chaves PHM, Kestenbaum BR, Kuller LH, Langa KM, Lopez OL, Llewellyn DJ. Vitamin D and risk of neuroimaging abnormalities. PLoS One. 2016;11:e0154896.

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selected published articles

Jacob ME, Yee LM, Diehr PH, Arnold AM, Thielke SM, Chaves PHM, Gobbo LD, Hirsch C, Siscovick D, Newman AB. Can a healthy lifestyle compress the disabled period in older adults? J Am Geriatr Soc.2016;64:1952-1961.

Del Gobbo L, Imamura F, Aslibekyan S, Marklund M, Virtanen J, Wennberg M, Yakoob MY, Chiuve SE, dela Cruz L, Frazier-Wood L, Fretts A, Guallar E, Matsumoto C, Prem K, Tanaka T, Wu J, Zhou X, Gaziano J, Helmer C, Ingelsson E, Tunstall-Pedoe H, Yuan J-M, Barberger-Gateau P, Campos H, Chaves PHM, Djoussé L, Giles G, Gómez-Aracena J, Hodge A, Hu F, Jansson J-H, Johansson I, Khaw K-T, Koh W-P, Lemaitre R, Lind L, Luben R, Rimm EB, Risérus U, Samieri C, Selberg-Franks P, Siscovick D, Stampfer M, Steffen L, Steffen BT, Tsai MY, van Dam RM, Voutilainen S, Willett W, Woodward M . ω-3 Polyunsaturated Fatty Acid Biomarkers and Coronary Heart Disease: Pooling Project of 19 Cohort Studies. JAMA Intern Med. 2016;176:1155-1166. doi: 10.1001/jamainternmed.2016.2925.

PMID: 27357102 Adriana Foster, MD, Professor, Psychiatry and Behavioral Health Foster A, Robb A, Cordar A, Chaudhary N, Noseworthy D, Lok B. Denise: a virtual patient. MedEdPORTAL Publications.

2015;11:10145.

Foster A, Johnson T, Liu H, Cluver J, Johnson S, Neumann C, Marcangelo M, Rosenthal R, Ton H, Davidson B, Klapheke M. Student assessment of psychiatry clinical simulation teaching modules. Medical Teacher. 2015;37:300. doi: 10.3109/0142159X.2014.948834.

Pedro Greer, MD, Professor and Chair, Humanities, Health, and Society Greer P. Medical education–a focus on social accountability. Minnesota Health Care News. 2016;14:5.

Dimitrios Ioannou, PhD, Assistant Professor, Human and Molecular Genetics Ioannou D, Kandukuri L, Simpson JL, Tempest HG. Chromosome territory repositioning induced by PHA-activation of lymphocytes: A 2D and 3D appraisal. Mol Cytogenet. 2015;8:47. doi: 10.1186/s13039-015-0146-3. eCollection 2015. PMID: 26146516.

Ioannou D, Miller D, Griffin DK, Tempest HG. Impact of sperm DNA chromatin in the clinic. J Assist Reprod Genet. 2016;33:157-166. doi: 10.1007/s10815-015-0624-x. PMID: 26678492.

Turner K, Fowler K, Fonseka G, Griffin D, Ioannou D. Multicolor detection of every chromosome as a means of detecting mosaicism and nuclear organization in human embryonic nuclei. Panminerva Med. 2016;58:175-190. PMID: 2698252.

Sakhrat Khizroev, PhD, Professor, Cellular Biology and Pharmacology Hong J, Hadjikhani A, Stone M, Allen F, Safonov V, Liang P, Bokor J, Khizroev S. The physics of spin-transfer torque switching in magnetic tunneling junctions in sub-10-nm size range. IEEE Trans Magn. 2016;52:1400504.

Guduru R, Liang P, Hong J, Rodzinski A, Hadjikhani A, Horstmyer J, Levister E, Khizroev S. Magnetoelectric “spin” on stimulating the brain. Nanomedicine (Lond). 2015;10:2051-2061.

Iveris Martinez, PhD, Associate Professor, Humanities, Health, and Society Martinez IL, Castellanos N., Carr C, Plescia C J, Rodriguez A L, Thommi S, Zaremski L, Weithorn D, Maisel P, Wells AL. Increasing awareness on health care access in Florida: a community-based medical-legal practicum project. Prog Community Health Partnersh 2016;10:141-147. PMID: 25953069. DOI: 10.2217/nnm.15.52 Martínez IL. Integrating anthropology in medical education: opportunities, challenges, and lessons. Practicing Anthropology.

2015;37:35-39.

Kalai Mathee, PhD, Professor, Human and Molecular Genetics Lee M, Dhar S, De Benedetti S, Hesek D, Boggess B, Blázquez B, Mathee K, Mobashery S. Muropeptide pool and the elicitors of ß-lactam-antibiotic resistance in pseudomonas aeruginosa. Angew Chem Int Ed Engl. 2016;55:6882-6886. doi: 10.1002/ anie.201601693.

Zincke D, Balasubramanian D, Silver LL, Mathee K. Characterization of a carbapenem-hydrolyzing enzyme, PoxB, in pseudomonas aeruginosa PAO1. Antimicrob Agents Chemother. 2015;60:936-945. doi: 10.1128/AAC.01807-15.

Tatke G, Kumari H, Silva-Herzog E, Ramirez L, Mathee K. Pseudomonas aeruginosa MifS-MifR two competent system is specific for a-ketoglutarate utilization. PLOS One. 2015;10:e0129629. doi: 10.1371/journal.pone.0129629.

Fernandez M, Riveros JD, Campos M, Mathee K, Narasimhan G. Microbial “social networks.” BMC Genomics. 2015;16(suppl 11):S6.

Madhavan Nair, PhD, Chair and Distinguished Professor, Immunology Jayant RD, Nair M. Role of biosensing technology for neuroAIDS management. J Biosens Bioelectron. 2016;7:e141. PMID: 27280058.

Andrea Raymond, PhD, Assistant Professor, Immunology Khan MB, Lang MJ, Huang MB, Raymond A, Bond VC, Shiramizu B, Powell MD. Nef exosomes isolated from the plasma of individuals with HIV-associated dementia (HAD) can induce Aβ (1-42) secretion in SH-SY5Y neural cells. J Neurovirol. 2016;22:179-190. PMID: 26407718.

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John Rock, MD, Founding Dean, HWCOM; Senior VP for Health Affairs; and Professor, Obstetrics and Gynecology Jones HW III, Rock JA, eds. TeLinde’s Operative Gynecology. 11th ed. Philadelphia, Pa: Wolters-Kluwer; 2015.

Gebhart JB, Breech LL, Hurst BS, Rock JA. Congenital Vaginal Abnormalities. In: Baggish MS, Karram MM, eds. Atlas of Pelvic Anatomy and Gynecologic Surgery. 4th ed. Philadelphia, Pa: Elsevier; 2016:779-798.

Barry Rosen, PhD, Distinguished Professor, Cellular Biology and Pharmacology Chen J, Rosen BP. Organoarsenical biotransformations by Shewanella putrefaciens. Environ Sci Technol. 2016;50:7956-7963.

PMID:27366920.

Huang K, Chen C, Zhang J, Tang Z, Shen Q, Rosen BP, Zhao FJ. Efficient arsenic methylation and volatilization mediated by a novel bacterium from an arsenic-contaminated paddy soil. Environ Sci Technol. 2016;50:6389-6396. doi: 10.1021/acs.est.6b01974.

PMID:27258163.

Nadar VS, Yoshinaga M, Pawitwar SS, Kandavelu P, Sankaran B, Rosen BP. Structure of the ArsI C-As lyase: insights into the mechanism of degradation of organoarsenical herbicides and growth promoters. J Mol Biol. 2016;428:2462-2473. doi: 10.1016/j. jmb.2016.04.022. PMID:27107642.

Yang HC, Rosen BP. New mechanisms of bacterial arsenic resistance. Biomed J. 2016;39:5-13. doi: 10.1016/j. bj.2015.08.003.

PMID:27105594.

Li J, Mandal G, Rosen BP. Expression of arsenic resistance genes in the obligate anaerobe bacteroides vulgatus ATCC 8482, a gut microbiome bacterium. Anaerobe. 2016;39:117-123. doi: 10.1016/j.anaerobe. 2016.03.012. PMID:27040269.

Duan GL, Hu Y, Schneider S, McDermott J, Chen J, Sauer N, Rosen BP, Daus B, Liu Z, Zhu YG. Inositol transporters AtINT2 and AtINT4 regulate arsenic accumulation in Arabidopsis seeds. Nat Plants. 2015;2:15202. doi: 10.1038/nplants.2015.202. PMID:27004129.

Tang Z, Lv Y, Chen F, Zhang W, Rosen BP, Zhao FJ. Arsenic methylation in arabidopsis thaliana expressing an algal arsenite methyltransferase gene increases arsenic phytotoxicity. J Agric Food Chem. 2016;64:2674-2681. doi: 10.1021/acs.jafc.6b00462.

PMID:26998776.

Chen J, Yoshinaga M, Garbinski LD, Rosen BP. Synergistic interaction of glyceraldehydes-3-phosphate dehydrogenase and ArsJ, a novel organoarsenical efflux permease, confers arsenate resistance. Mol Microbiol. 2016;100:945-953. doi: 10.1111/mmi.13371.

PMID:26991003.

Kumar NV, Yang J, Pillai JK, Rawat S, Solano C, Kumar A, Grøtli M, Stemmler TL, Rosen BP, Tamás MJ. Arsenic directly binds to and activates the yeast AP-1-like transcription factor Yap8. Mol Cell Biol. 2015;36:913-922. doi: 10.1128/MCB.00842-15.

PMID:26711267.

Dong H, Madegowda M, Nefzi A, Houghten RA, Giulianotti MA, Rosen BP. Identification of small molecule inhibitors of human as(III) S-adenosylmethionine methyltransferase (AS3MT). Chem Res Toxicol. 2015;28:2419-2425. doi: 10.1021/acs.chemrestox.5b00432.

PMID:26577531.

Ajees AA, Rosen BP. As(III) S-adenosylmethionine methyltransferases and other arsenic binding proteins. Geomicrobiol J. 2015;32:570-576. PMID:26366023.

Chen J, Madegowda M, Bhattacharjee H, Rosen BP. ArsP: a methylarsenite efflux permease. Mol Microbiol. 2015;98:625-635. doi: 10.1111/mmi.13145. PMID:26234817.

Huang K, Chen C, Shen Q, Rosen BP, Zhao FJ. Genetically engineering bacillus subtilis with a heat-resistant arsenite methyltransferase for bioremediation of arsenic-contaminated organic waste. Appl Environ Microbiol. 2015;81:6718-6724. doi: 10.1128/AEM.0153515. PMID:26187966.

Maizel D, Utturkar SM, Brown SD, Ferrero MA, Rosen BP. Draft genome sequence of Brevibacterium linens AE0388, an extremely arsenic-resistant bacterium. Genome Announc. 2015;3:e00316-15. doi: 10.1128/ genomeA.00316-15. PMID:25883298.

Ana Viamonte Ros, MD, Associate Professor, Associate Dean for Women in Medicine and Science Nicholas PK, Breaky S, Winter S, Pusey-Reid E, Viamonte-Ros AM. Climate change, climate justice, and environmental health issues.

In: Breakey S, ed. Global Nursing: From Florence Nightingale to the 21st Century. New York: NY: Springer Publishing Company; 2015.

Eugenio Rothe, MD, Professor, Psychiatry and Behavioral Health Rothe EM, Lewis JE, Aftab A, Mehdi S, Lages L, Sharma R, Hershorin E, Jaquez M, Padilla A, Deray M. An assessment of comorbidity and social demographics in a primarely African-American and Hispanic population of boys with ADHD treated in psychiatric/nonpsychiatric and public/private clinics in Miami, Florida. J Child and Adolesc Behav. 2016;4:1-7. http://dx.doi.org/10.4172/23754494.1000277 Rothe E M, Pumariega A J, Castillo-Matos H. Mental health of child and adolescent refugees. In: Ness I, Bellwood P, eds.

Encyclopedia of Global Human Migration. New York, NY: Wiley; 2015.

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selected published articles

Rothe E M, Mella Mejias C. Historia de la Psiquiatria y de la Sociedad Dominicana de Psiquiatria (Vol. II). In: Stern-Diaz HS, ed.

Apuntes y Documentos para la historia de la medicina en Republica Dominicana del Siglo XX. Santo Domingo, Republica Dominicana: Editora Buho; 2015.

Pumariega A, Cagande C, Rothe EM. Mental Health and Psychosocial Risks in Latino Youth. In: Akhtar S, Bertoglia SM, eds. The American Latino: Psychodynamic perspectives on culture and mental health issues. New York, NY: Rowman and Littlefield; 2015.

Carolyn Runowicz, MD, Executive Associate Dean Academic Affairs and Professor, Obstetrics and Gynecology Runowicz CD, Leach CR, Henry NL, Henry KS, Mackey HT, Cowens-Alvarado RL, Cannady RS, Pratt-Chapman ML, Edge SB, Jacobs LA, Hurria A, Marks LB, LaMonte SJ, Warner E, Lyman GH, Ganz PA. American Cancer Society/American Society of Clinical Oncology Breast Cancer Survivorship Care Guideline. J Clin Oncol. 2016;34:611-635. doi: 10.1200/JCO.2015.64.3809. PMID: 26644543.

Rodzinski A, Guduru R, Liang P, Hadjikhani A, Stewart T, Stimphil E, Runowicz C, Cote R, Altman N, Datar R, Khizroev S. Targeted and controlled anticancer drug delivery and release with magnetoelectric nanoparticles. Sci Rep. 2016;6:20867. doi: 10.1038/srep20867.

PMID: 26875783.

Chlebowski RT, Anderson GL, Sarto GE, Haque R, Runowicz CD, Aragaki AK, Thomson CA, Howard BV, Wactawski-Wende J, Chen C, Rohan TE, Simon MS, Reed SD, Manson JE. Continuous combined estrogen plus progestin and endometrial cancer: the Women’s Health Initiative randomized trial. J Natl Cancer Inst. 2015;103:djv350. doi: 10.1093/jnci/djv350. PMID: 26668177.

Runowicz CD, Leach CR, Henry NL, Henry KS, Mackey HT, Cowens-Alvarado RL, Cannady RS, Pratt-Chapman ML, Edge SB, Jacobs LA, Hurria A, Marks LB, LaMonte SJ, Warner E, Lyman GH, Ganz PA. American Cancer Society/American Society of Clinical Oncology Breast Cancer Survivorship Care Guideline. CA Cancer J Clin. 2016;66:43-73. doi: 10.3322/caac.21319. PMID: 26641959.

Tefferi A, Kantarjian H, Rajkumar SV, Baker LH, Abkowitz JL, Adamson JW, Advani RH, Allison J, Antman KH, Bast RC Jr, Bennett JM, Benz EJ Jr, Berliner N, Bertino J, Bhatia R, Bhatia S, Bhojwani D, Blanke CD, Bloomfield CD, Bosserman L, Broxmeyer HE, Byrd JC, Cabanillas F, Canellos GP, Chabner BA, Chanan-Khan A, Cheson B, Clarkson B, Cohn SL, Colon-Otero G, Cortes J, Coutre S, Cristofanilli M, Curran WJ Jr, Daley GQ, DeAngelo DJ, Deeg HJ, Einhorn LH, Erba HP, Esteva FJ, Estey E, Fidler IJ, Foran J, Forman S, Freireich E, Fuchs C, George JN, Gertz MA, Giralt S, Golomb H, Greenberg P, Gutterman J, Handin RI, Hellman S, Hoff PM, Hoffman R, Hong WK, Horowitz M, Hortobagyi GN, Hudis C, Issa JP, Johnson BE, Kantoff PW, Kaushansky K, Khayat D, Khuri FR, Kipps TJ, Kripke M, Kyle RA, Larson RA, Lawrence TS, Levine R, Link MP, Lippman SM, Lonial S, Lyman GH, Markman M, Mendelsohn J, Meropol NJ, Messinger Y, Mulvey TM, O’Brien S, Perez-Soler R, Pollock R, Prchal J, Press O, Radich J, Rai K, Rosenberg SA, Rowe JM, Rugo H, Runowicz CD, Sandmaier BM, Saven A, Schafer AI, Schiffer C, Sekeres MA, Silver RT, Siu LL, Steensma DP, Stewart FM, Stock W, Stone R, Storb R, Strong LC, Tallman MS, Thompson M, Ueno NT, Van Etten RA, Vose JM, Wiernik PH, Winer EP, Younes A, Zelenetz AD, LeMaistre CA. In support of a patient-driven initiative and petition to lower the high price of cancer drugs. Mayo Clin Proc. 2015;90:996-1000. doi: 10.1016/j.mayocp.2015.06.001. PMID:26211600.

Margaret Sibley, PhD, Assistant Professor, Psychiatry and Behavioral Health Babinski DE, Pelham WE, Molina BSG, Gnagy EM, Waschbusch DA, Wymbs BT, Sibley MH, Kuriyan AB. Maternal ADHD, parenting, and psychopathology among mothers of adolescents with ADHD. J Atten Disord. 2016;20:458-468. DOI: 10.1177/1087054712461688. PMID: 23160485.

Lee SS, Sibley MH, Epstein JN. Attention-deficit/hyperactivity disorder across development: Predictors, resilience, and future directions. J Abnorm Psychol. 2016;125:151-153. DOI: 10.1037/abn0000114. PMID: 26854501.

Lahey BB, Lee SS, Sibley MH, Applegate B, Molina BSG, Pelham WE. Predictors of adolescent outcomes among 4-6-year-old children with attention-deficit/hyperactivity disorder. J Abnorm Psychol. 2016;125:168-181. DOI: 10.1037/abn0000086. PMID: 26854503 Sibley MH, Campez M, Perez A, Morrow AS, Merrill BM, Altszuler AA, Coxe S, Yeguez CE. Parent management of organization, time management, and planning deficits among adolescents with ADHD. J Psychopathol Behav. 2016;38:216-228.

Sibley MH, Kuriyan AB. DSM-5 changes enhance parent identification of symptoms in adolescents with ADHD. Psychiatry Res. 2016;242:180-185. DOI: 10.1016/j.psychres.2016.05.036. PMID: 27288736.

Rebecca Toonkel, MD, Assistant Professor, Humanities, Health, and Society Tashiro J, Elliot SJ, Gerth DJ, Xia X, Pereira-Simon S, Choi R, Catanuto P, Shahzeidi S, Toonkel RL, Shah RH, El Salem F, Glassberg MK. Therapeutic benefits of young, but not old, adipose-derived mesenchymal stem cells in a chronic mouse model of bleomycininduced pulmonary fibrosis. Transl Res. 2015;166:554-567. DOI: 10.1016/j.trsl.2015.09.004. PMID: 26432923.

Juan Zevallos, MD, Professor, Medical and Population Health Sciences Research Zevallos JC, Ciliberti-Vargas MA, Wang K, Dong C, Carrasquillo O, Garcia-Rivera EJ, Carrasquillo O, Garcia-Rivera EJ, Nobo U, Santiago FL, Perez EJ, Rundek T, Romano JG, Burgin WS, Koch S, Meschia JF, Nelson JA, Robichaux M, Rose DZ, Waters MF, Sacco RL. Stroke care improvement trends in Puerto Rico hospitals participating in the Florida-Puerto Rico Collaboration to Reduce Stroke Disparities (FL-PR CReSD) study-the NINDS Stroke Prevention Intervention Research Program [abstract]. Stroke. 2015;46(suppl 1). ATP261.

Sacco RL, Gardener H, Wang K, Dong C, Ciliberti-Vargas MA, Romano JG, Burgin WS, Carrasquillo O, Garcia-Rivera EJ, Koch S, Meschia JF, Nelson JA, Nobo U, Robichaux M, Rose DZ, Sanrtiago FL, Waters MF, Zevallos JC, Rundek T. Race-ethnic stroke disparities in the Florida-Puerto Rico Collaboration to Reduce Stroke Disparities Study-the NINDS Stroke Prevention Intervention Research Program [abstract]. Stroke. 2015;46(suppl 1). AWP283.

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Asdaghi N, Wang K, Gardener H, Dong C, Ciliberti-Vargas MA, Rose DZ, Santiago FL, Romano JG, Burgin WS, Carrasquillo O, GarciaRivera EJ, Koch S, Meschia JF, Nelson JA, Nobo U, Robichaux M, Waters MF, Zevallos JC, Sacco RL, Rundek T. Lower thrombolysis rates in women with acute ischemic stroke in the Florida-Puerto Rico Collaboration to Reduce Stroke Disparities Study-the NINDS Stroke Prevention Intervention Research Program [abstract]. Stroke. 2015;46(suppl 1). ATP262.

Zevallos JC, Zevallos R, Collada B, Marticorena R, Pandya R, Paredes ML, Lozano JM. High troponin levels and increased risk of serious cardiac complications and death in Puerto Ricans with acute myocardial infarction. Revista DesafĂ­os. 2015;9:9-16.

Alanazi B, Aljodai M, Almutairi M, Acuna J, Aldaham S, Zevallos JC. Gender difference in mortality among Hispanics hospitalized with acute ischemic stroke in Puerto Rico. Hamdan Med J. 2016;8(suppl).

Smirnoff L, Moses A, Zevallos JC. Alcoholism and in-hospital mortality among hemorrhagic stroke patients in Puerto Rico. (P1. 263).

Neurol. 2016;86(suppl). P1.263.

Rodriguez-Vila O, Campos MA, Lapetina F, Escabi J, Nieves C, Bermudez E, Zevallos JC, Mehta S; VA Caribbean Healthcare System.

Status of STEMI-PCI in the US territories: the Puerto Rico Infarction National Collaborative Experience (PRINCE) Initiative. JACC. 2016;67(13_S):608.

Zevallos JC, Ciliberti-Vargas MA, Wang K, Gutierrez CM, Garcia-Rivera EJ, Nobo U, Santiago F, Romano JG, Asdaghi N, Dong C, Carrasquillo O, Waddy SP, Robichaux M, Perez EJ, Waters MF, Rundek T, Sacco RL. Sex disparities in stroke care in Puerto Rico hospitals participating in the Florida-Puerto Rico Collaboration to Reduce Stroke Disparities (FL-PR CReSD) Study. Stroke.

2016;47(suppl 1). AWP285.

Collaborations Alexander Agoulnik, PhD, Professor, Human and Molecular Genetics Irina Agoulnik, PhD, Associate Professor, Human and Molecular Genetics Huang Z, Myhr C, Bathgate RAD, Ho B, Bueno A, Hu X, Xiao J, Southall N, Barnaeva E, Agoulnik IU, Marugan J, Ferrer M, Agoulnik AI. Activation of relaxin family receptor 1 from different mammalian species by relaxin peptide and small-molecule agonist ML290.

Front Endocrinol (Lausanne). 2015;6:128. doi: 10.3389/fendo.2015.00128. PMID:26347712.

Agoulnik IU, Agoulnik AI. Long-lasting consequences of testosterone exposure (News and Views). Endocrinol. 2015;156:3488-3489. doi: 10.1210/en.2015-1719. PMID:26380936.

Hu X, Myhr C, Huang Z, Xiao J, Barnaeva E, Ho BA, Agoulnik IU, Ferrer M, Marugan JJ, Southall N, Agoulnik AI. Structural insights into the activation of human relaxin family peptide receptor 1 by small-molecule agonists. Biochemistry. 2016;55:1772-1783. doi: 10.1021/acs.biochem.5b01195. PMID:26866459.

Lopez SM, Agoulnik AI, Zhang M, Peterson LE, Suarez E, Gandarillas GA, Frolov A, Li R, Rajapakshe K, Coarfa C, Ittmann M, Weigel NL, Agoulnik IU. Nuclear receptor corepressor 1 expression and output declines with prostate cancer progression. Clin Cancer Res. 2016;22:3937-3949. PMID: 26968201.

Marisela Agudelo, PhD, Assistant Professor, Immunology Venkata Atluri, PhD, Assistant Professor, Immunology Nazira El-Hage, PhD, Associate Professor, Immunology Ajeet Kaushik, PhD, Assistant Professor, Immunology Madhavan Nair, PhD, Chair and Distinguished Professor, Immunology Sudheesh Pilakka-Kanthikeel, PhD, Assistant Professor, Immunology Aileen Marty, MD, Professor, Humanities, Health, and Society Andrea Raymond, PhD, Assistant Professor, Immunology Upal Roy, PhD, PhD, Assistant Professor, Immunology Samikkannu Thangavel, PhD, Assistant Professor, Immunology Kaushik A, Jayant RD, Nair M. Advancements in nano-enabled therapeutics for neuroHIV management. Int J Nanomed.

2016;11:4317-4325.

Kaushik A, Jayant RD, Nikkhah-Moshaie R, Bhardwaj V, Roy U, Huang Z, Ruiz A, Yndart A, Atluri V, El-Hage N, Khalili K, Nair M. Magnetically guided central nervous system delivery and toxicity evaluation of magneto-electric nanocarriers. Sci Rep. 2016;6:25309. PMID: 27143580.

Kaushik A, Jayant RD, Tiwari S, Vashist A, Nair M. Nano-biosensors to detect beta-amyloid for Alzheimer’s disease management.

Biosens Bioelectron. 2016;80:273-287. PMID: 26851586.

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selected published articles

Kaushik A, Runowicz CD, Jayant RD, and Nair M. Lab-on-a-chip for ovarian cancer monitoring. J Pers Nanomed. 2015;1:38-39.

Kaushik A, Tiwari S, Jayant RD, Marty A, Nair M. Towards detection and diagnosis of Ebola virus disease at point-of-care. Biosens Bioelectron. 2016;75:254-272. PMID: 26319169.

Kaushik A, Kumar R, Jayant RD, Nair M. Nanostructured gas sensors for health care: an overview. J Pers Nanomed. 2015;1:10-23.

PMID: 26491544.

Agudelo M, Figueroa G, Parira T, Yndart A, MuĂąoz K, Atluri V, Samikkannu T, Nair MP. Profile of class I histone deacetylases (HDAC) by human dendritic cells after alcohol consumption and in vitro alcohol treatment and their Implication in oxidative stress: role of HDAC inhibitors trichostatin A and mocetinostat. PLOS One. 2016;11:e0156421. PMID: 27249803.

Tomitaka A, Takemura Y, Huang Z, Roy U, Nair M. Recent advances in magnetoliposomes as drug delivery carriers. J Pers Nanomed.

2015;1:51-57.

Sagar V, Atluri VSR, Tomitaka A, Shah P, Nagasetti A, Pilakka-Kanthikeel S, El-Hage N, McGoron A, Takemura Y, Nair M. Coupling of transient near infrared photonic with magnetic nanoparticle for potential dissipation-free biomedical application in brain. Sci Rep. 2016;6:29792.

Figueroa G, Parira T, Laverde A, Casteleiro G, El-Mabhouh A, Nair MP, Agudelo M. Characterization of human monocyte-derived dendritic cells by imaging flow cytometry: a comparison between two monocyte isolation protocols. J Vis Exp. 2016;(116):e54296.

Agudelo M, Figueroa G, Yndart A, Casteleiro G, MuĂąoz K, Samikkannu T, Atluri V, Nair MP. Alcohol and cannabinoids differentially affect HIV infection and function of human monocyte-derived dendritic cells (MDDC). Front Microbiol. 2015;6:1452. PMID: 26733986.

Raymond AD, Diaz P, Chevelon S, Agudelo M, Yndart-Arias A, Ding H, Kaushik A, Jayant RD, Nikkhah-Moshaie R, Roy U, PilakkaKanthikeel S, Nair MP. Microglia-derived HIV Nef+ exosome impairment of the blood-brain barrier is treatable by nanomedicinebased delivery of Nef peptides. J Neurovirol. 2016;22:129-139. PMID: 26631079.

Yndart A, Kaushik A, Agudelo M, Raymond A, Atluri VS, Saxena S, Nair M. Investigation of neuropathogenesis in HIV-1 clade B and C infection associated with IL-33 and ST2 regulation. ACS Chem Neurosci. 2015;6:1600-1612. PMID: 26110635.

Roy U, Atluri VS, Agudelo M, Yndart A, Huang Z, Nair M. DJ1 expression downregulates in neuroblastoma cells (SK-N-MC) chronically exposed to HIV-1 and cocaine. Front Microbiol. 2015;6:749. PMID: 26284039.

Roy U, Ding H, Pilakka-Kanthikeel S, Raymond AD, Atluri V, Yndart A, Kaftanovskaya EM, Batrakova E, Agudelo M, Nair M. Preparation and characterization of anti-HIV nanodrug targeted to microfold cell of gut-associated lymphoid tissue. Int J Nanomedicine.

2015;10:5819-5835. PMID: 26425084.

Jayant RD, Sosa D, Kaushik A, Vashist A, Nair M. Current status of non-viral gene therapy for CNS disorders. Expert Opin Drug Deliv.

2016;1:1-13. PMID: 27249310.

Atluri V, Jayant RD, Pilakka-Kanthikeel S, Kaushik A, Yndart A, Nair M. Development TIMP1 magnetic nanoformulation for regulation of synaptic plasticity in HIV-1 infection. Int J Nanomedicine. 2016;11:4287-4298.

Dimitrios Ioannou, PhD, Assistant Professor, Human and Molecular Genetics Helen Tempest, PhD, Assistant Professor, Human and Molecular Genetics Ioannou D, Kandukuri L, Simpson JL, Tempest HG. Chromosome territory repositioning induced by PHA-activation of lymphocytes: a 2D and 3D appraisal. Mol Cytogenet. 2015;8:47. doi: 10.1186/s13039-015-0146-3. eCollection 2015. PMID: 26146516.

Ioannou D, Miller D, Griffin DK, Tempest HG. Impact of sperm DNA chromatin in the clinic. J Assist Reprod Genet. 2016; 33:157-166. doi: 10.1007/s10815-015-0624-x. PMID: 26678492.

Ajeet Kaushik, PhD, Assistant Professor Immunology Aileen Marty, MD, Professor, Humanities, Health, and Society Madhavan Nair, PhD, Chair and Distinguished Professor, Immunology Kaushik A, Tiwari S, Jayant D, Marty A, Nair M. Towards detection and diagnosis of Ebola virus disease at point-of-care. Biosens Bioelectron. 2016;75:254-272.

Jenny Fortun, PhD, Associate Professor, Cellular Biology and Pharmacology Marin Gillis, PhD, Professor, Humanities, Health, and Society Helen Tempest, PhD, Assistant Professor, Human and Molecular Genetics Tracey Weiler, PhD, Assistant Professor, Humanities, Health, and Society Tempest H, Gillis M, Weiler T, Fortun J. Design of a platform to discuss ethical considerations of preimplantation genetic diagnosis: a case for integration of ethics in foundational science medical curriculum. Med Sci Educ. 2016;26:213-219.

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Carolyn Runowicz, MD, Executive Associate Dean, Academic Affairs and Professor, Obstetrics and Gynecology Sakhrat Khizroev, PhD, Professor, Cellular Biology and Pharmacology Rodzinski A, Guduru R, Liang P, Hadjikhani A, Stewart T, Stimphil E, Runowicz C, Cote R, Altman N, Datar R, Khizroev S. Targeted and controlled anticancer drug delivery and release with magnetoelectric nanoparticles. Sci Rep. 2016;6:20867.

Sanaz Kashan, MD, Assistant Professor, Humanities, Health, and Society Suzanne Minor, MD, Associate Professor, Humanities, Health, and Society Minor S, Kashan S, Castillo M. A team reacts to a patient’s death. Fam Med. 2015;47:813-814.

David Brown, MD, Associate Professor, Humanities, Health, and Society Jorge Camilo Mora, MD, Associate Professor, Humanities, Health, and Society Osondu CU, Aneni EC, Shaharyar S, Robertson L, Rouseff M, Das S, Spatz E, Younus A, Guzman H, Brown D, Santiago-Charles J, Ochoa T, Mora J, Gilliam C, Lehn V, Sherriff S, Tran T, Gonzalez A, Virani S, Feldman T, Agatston AS, Nasir K. The effectiveness of a worksite lifestyle intervention program on high-risk individuals as potential candidates for bariatric surgery: My Unlimited Potential (MyUP).

Popul Health Manag. 2016;19:368-375.

Jeremy Chambers, PhD, Assistant Professor, Cellular Biology and Pharmacology Dietrich Lorke, MD, PhD, Professor, Cellular Biology and Pharmacology Georg Petroianu, MD, PhD, Chair and Professor, Cellular Biology and Pharmacology Petroianu GA, Nurulain SM, Hasan MY, Kuča K, Lorke DE. Reversible cholinesterase inhibitors as pre-treatment for exposure to organophosphates: assessment using azinphos-methyl. J Appl Toxicol. 2015;35:493-499.

Prado A, Petroianu GA, Lorke DE, Chambers JW. A trivalent approach for determining in vitro toxicology: examination of oxime K027.

J Appl Toxicol. 2015;35:219-227.

Nurulain S, Prytkova T, Sultan AM, Ievglevskyi O, Lorke D, Yang KS, Petroianu G, Howarth FC, Kabbani N, Oz M. Inhibitory actions of bisabolol on α7-nicotinic acetylcholine receptors. Neuroscience. 2015;306:91-99.

Jenny Fortun, PhD, Associate Professor, Cellular Biology and Pharmacology Rebecca Toonkel, MD, Assistant Professor, Humanities, Health, and Society Fortun J, Toonkel R, Berrocal Y. Case-based discussion: hypertension. MedEdPORTAL Publications. 2015;11:9994.

Juan Acuña, MD, Chair and Associate Professor, Department of Medical and Population Health Sciences Research Juan Manuel Lozano, MD, Professor, Department of Medical and Population Health Juan Zevallos, MD, Professor, Medical and Population Health Sciences Research Zevallos JC, Zevallos R, Collada B, Marticorena R, Pandya R, Paredes ML, Lozano JM. High troponin levels and increased risk of serious cardiac complications and death in Puerto Ricans with acute myocardial infarction. Revista Desafíos. 2015;9:9-16.

Alanazi B, Aljodai M, Almutairi M, Acuna J, Aldaham S, Zevallos JC. Gender difference in mortality among Hispanics hospitalized with acute ischemic stroke in Puerto Rico. Hamdan Med J. 2016;8(suppl).

Zevallos JC, Wilcox ML, Jean N, Acuña JM. Profile of the older population living in Miami-Dade County, Florida: an observational study. Medicine (Baltimore). 2016;95:e3630.

Paulo Chaves, MD, PhD, Associate Professor, Humanities, Health, and Society Iveris Martinez, PhD, Associate Professor, Humanities, Health, and Society Alan Wells, PhD, Assistant Professor, Humanities, Health, and Society Martinez IL, Castellanos N, Carr C, Plescia CJ, Rodriguez AL, Thommi S, Weithorn D, Zaremski L, Maisel M, Wells A. Increasing awareness on health care access in Florida: a community-based medical-legal practicum project. Prog Community Health Partnersh.

2016;10:141-147. DOI: 10.1353/cpr.2016.0007. PMID: 27018363.

Martinez I, Chaves PHM, Pelaez M. Envejecimiento activo y participacion social. In: Abizanda SP, Rodriguez ML, eds. Tratado de Medicina Geriátrica. Madrid, Spain: Elsevier España; 2015.

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