The 4th Paradigm

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Workflow Inputs qtl_end_position

qtl_start_position

chromosome_name

genes_in_qtl mmusculus_gene_ensembl remove_uniprot_duplicates

remove_entrez_duplicates

create_report

merge_entrez_genes

merge_reports

merge_uniprot_ids REMOVE_NULLS_2

remove_Nulls

add_uniprot_to_string

add_ncbi_to_string

Kegg_gene_ids

Kegg_gene_ids_2

concat_kegg_genes regex_2

split_gene_ids

merge_kegg_references

split_for_duplicates remove_duplicate_kegg_genes Get_pathways Workflow Inputs regex

gene_ids

split_by_regex lister get_pathways_by_genes1 Merge_pathways concat_ids concat_gene_pathway_ids Merge_gene_pathways

pathway_desc Merge_pathway_desc

Workflow Outputs pathway_genes

merge_genes_and_pathways kegg_pathway_release binfo

pathway_desc

remove_pathway_duplicates

pathway_ids

merge_pathway_list_1

gene_descriptions

merge_genes_and_pathways_2

merge_pathway_desc

merge_pathway_list_2

merge_gene_desc

species

merge_genes_and_pathways_3

remove_pathway_nulls

remove_pathway_nulls_2

remove_nulls_3

getcurrentdatabase

Workflow Outputs kegg_pathway_release

merged_pathways

Workflow Outputs

Workflow Inputs

An_output_port

An_input_port

pathway_descriptions

A_local_service

pathway_ids

Beanshell

gene_descriptions

A_Soaplab_service

kegg_external_gene_reference

String_constant

report

ensembl_database_release

A_Biomart_Service

Figure 1.

A Taverna workflow that connects several internationally distributed datasets to identify candidate genes that could be implicated in resistance to African trypanosomiasis [11].

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