Lung Cancer •
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The conventional treatments of cancer like chemotherapy, surgery, and radiation have failed to eradicate lung cancer completely. In a report by World Health Organisation (WHO), dated 12 September 2018, it was observed that 1.8 million deaths happened due to Lung cancer that year which is the largest number as compared to other cancers! Henceforth it won’t be wrong to say that lung cancer is the deadliest cancer Now these days Lung Cancer is one of the most common forms of cancer. In United States it is one of the most frequent causes of cancer related mortality In United States breast cancer is also increasing which is the development of malignant tissue in the breast. There is a major difference between lung cancer and breast cancer.
Types of Lung Cancer We have two types of Lung Cancer • •
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Small cell lung cancer Non – small cell lung cancer Apart from these two types there is one more type that is mixed small cell/ large cell lung cancer. Some people think that smoking is the only cause of lung cancer but it has been found in non- smokers as well. The reasons of lung cancer in non-smokers are: Air pollution Hereditary causes Arsenic in drinking water Sometimes due to the exposure of chest area to radiation therapy Inhalation of asbestos fibers Inhalation of marijuana fumes also causes lung cancer
Why Tocotrienol?
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Antioxidants, especially Tocotrienol was observed to exhibit anti-cancer activity against lung cancer cells. Angiogenesis which is the process of formation of blood vessels in cancer cells like in your brain cancer. Apoptosis or programmed cell death is the process of elimination and death of cancer cellscaspase-8 and mitochondrial cyt.c release. Cell Proliferation is the process by which cancer cells copy their DNA and divide into two cancer cells during mitosis and rapidly multiply into more cancer cells. Chemoprevention and anti-cancer activity against lung cancer have been observed in Tocotrienols. Hypoxia adaptation of lung cancer cells was observed to be suppressed by Tocotrienol through the inhibition of Src-induced Akt activation and decreased HIF-2 alpha.
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