Contents Chapter 1
General introduction (review): Macrophages in colorectal cancer: current diagnostic opportunities
9
Chapter 2
Activated macrophages containing tumor marker in colon carcinoma: immunohistochemical proof of a concept
37
Chapter 3
Visualising CEA in activated macrophages using electron microscopy
53
Chapter 4
CEA in activated macrophages. New diagnostic possibilities for tumor markers in early colorectal cancer
73
Chapter 5
Reproducibility studies for experimental epitope detection in macrophages (EDIM)
89
Chapter 6
Predicting response using blood biomarkers and PET-CT during neoadjuvant chemoradiation in rectal cancer patients
107
Chapter 7
General discussion
135
Summary
157
Samenvatting
175
Valorisation
193
Dankwoord
201
Curriculum Vitae
211
List of publications
215
Abbreviations
219